Treponema denticola (strain ATCC 35405 / DSM 14222 / CIP 103919 / JCM 8153 / KCTC 15104)

Taxonomy: cellular organisms; Bacteria; Spirochaetes; Spirochaetia; Spirochaetales; Treponemataceae; Treponema; Treponema denticola

Average proteome isoelectric point is 6.84

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 2753 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|Q73LP7|Q73LP7_TREDE Uncharacterized protein OS=Treponema denticola (strain ATCC 35405 / DSM 14222 / CIP 103919 / JCM 8153 / KCTC 15104) OX=243275 GN=TDE_1815 PE=4 SV=1
MM1 pKa = 7.73EE2 pKa = 5.96IDD4 pKa = 3.06IADD7 pKa = 5.24FISGYY12 pKa = 10.18KK13 pKa = 9.79SEE15 pKa = 4.47QFVSNYY21 pKa = 10.63DD22 pKa = 3.02DD23 pKa = 3.42WNYY26 pKa = 11.12KK27 pKa = 10.3DD28 pKa = 4.56VISHH32 pKa = 6.19LFEE35 pKa = 5.49WIMM38 pKa = 4.17

Molecular weight: 4.65 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|Q73Q91|Q73Q91_TREDE Ankyrin repeat protein OS=Treponema denticola (strain ATCC 35405 / DSM 14222 / CIP 103919 / JCM 8153 / KCTC 15104) OX=243275 GN=TDE_0552 PE=4 SV=1
MM1 pKa = 7.58GNFPITNYY9 pKa = 10.15KK10 pKa = 9.73LKK12 pKa = 10.77NRR14 pKa = 11.84LEE16 pKa = 4.6CGEE19 pKa = 4.22SSGSGRR25 pKa = 11.84FFIRR29 pKa = 11.84RR30 pKa = 11.84GHH32 pKa = 7.24ADD34 pKa = 2.92TCLRR38 pKa = 11.84AGTLRR43 pKa = 11.84KK44 pKa = 7.82TCRR47 pKa = 11.84LPP49 pKa = 3.59

Molecular weight: 5.53 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

2753

0

2753

863642

30

3320

313.7

35.36

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

6.978 ± 0.057

1.155 ± 0.018

5.3 ± 0.037

7.162 ± 0.051

5.356 ± 0.045

6.306 ± 0.052

1.455 ± 0.015

8.517 ± 0.048

8.62 ± 0.048

9.559 ± 0.05

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.344 ± 0.025

5.126 ± 0.04

3.407 ± 0.029

2.722 ± 0.021

3.754 ± 0.029

6.78 ± 0.038

5.001 ± 0.036

5.674 ± 0.036

0.882 ± 0.014

3.9 ± 0.042
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski