Amino acid dipepetide frequency for Fusarium kuroshium

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	8.635AlaAla: 8.635 ± 0.049	1.171AlaCys: 1.171 ± 0.012	4.212AlaAsp: 4.212 ± 0.025	5.125AlaGlu: 5.125 ± 0.044	3.219AlaPhe: 3.219 ± 0.027	5.634AlaGly: 5.634 ± 0.034	1.697AlaHis: 1.697 ± 0.017	4.471AlaIle: 4.471 ± 0.029	4.096AlaLys: 4.096 ± 0.03	7.745AlaLeu: 7.745 ± 0.045	2.041AlaMet: 2.041 ± 0.016	2.789AlaAsn: 2.789 ± 0.019	4.667AlaPro: 4.667 ± 0.044	3.243AlaGln: 3.243 ± 0.027	4.675AlaArg: 4.675 ± 0.028	6.955AlaSer: 6.955 ± 0.038	5.136AlaThr: 5.136 ± 0.032	5.338AlaVal: 5.338 ± 0.028	1.297AlaTrp: 1.297 ± 0.015	2.145AlaTyr: 2.145 ± 0.018	0.0AlaXaa: 0.0 ± 0.0
Cys	0.962CysAla: 0.962 ± 0.012	0.277CysCys: 0.277 ± 0.008	0.747CysAsp: 0.747 ± 0.011	0.677CysGlu: 0.677 ± 0.011	0.596CysPhe: 0.596 ± 0.008	0.993CysGly: 0.993 ± 0.014	0.376CysHis: 0.376 ± 0.008	0.796CysIle: 0.796 ± 0.009	0.574CysLys: 0.574 ± 0.01	1.376CysLeu: 1.376 ± 0.015	0.277CysMet: 0.277 ± 0.007	0.456CysAsn: 0.456 ± 0.008	0.732CysPro: 0.732 ± 0.011	0.521CysGln: 0.521 ± 0.008	0.834CysArg: 0.834 ± 0.011	0.982CysSer: 0.982 ± 0.013	0.747CysThr: 0.747 ± 0.013	0.875CysVal: 0.875 ± 0.014	0.25CysTrp: 0.25 ± 0.006	0.385CysTyr: 0.385 ± 0.007	0.0CysXaa: 0.0 ± 0.0
Asp	4.773AspAla: 4.773 ± 0.028	0.702AspCys: 0.702 ± 0.011	4.636AspAsp: 4.636 ± 0.04	4.657AspGlu: 4.657 ± 0.029	2.302AspPhe: 2.302 ± 0.017	4.267AspGly: 4.267 ± 0.029	1.271AspHis: 1.271 ± 0.014	3.133AspIle: 3.133 ± 0.023	2.641AspLys: 2.641 ± 0.021	5.254AspLeu: 5.254 ± 0.031	1.377AspMet: 1.377 ± 0.014	1.955AspAsn: 1.955 ± 0.016	3.41AspPro: 3.41 ± 0.025	1.999AspGln: 1.999 ± 0.02	3.027AspArg: 3.027 ± 0.026	4.151AspSer: 4.151 ± 0.028	3.024AspThr: 3.024 ± 0.022	3.747AspVal: 3.747 ± 0.029	1.003AspTrp: 1.003 ± 0.012	1.593AspTyr: 1.593 ± 0.016	0.0AspXaa: 0.0 ± 0.0
Glu	5.658GluAla: 5.658 ± 0.033	0.703GluCys: 0.703 ± 0.01	4.254GluAsp: 4.254 ± 0.03	5.454GluGlu: 5.454 ± 0.045	2.042GluPhe: 2.042 ± 0.019	3.838GluGly: 3.838 ± 0.025	1.418GluHis: 1.418 ± 0.015	3.013GluIle: 3.013 ± 0.023	3.684GluLys: 3.684 ± 0.033	5.246GluLeu: 5.246 ± 0.029	1.536GluMet: 1.536 ± 0.015	2.251GluAsn: 2.251 ± 0.02	3.12GluPro: 3.12 ± 0.041	2.366GluGln: 2.366 ± 0.02	3.79GluArg: 3.79 ± 0.03	4.295GluSer: 4.295 ± 0.03	3.772GluThr: 3.772 ± 0.03	3.675GluVal: 3.675 ± 0.027	0.958GluTrp: 0.958 ± 0.011	1.687GluTyr: 1.687 ± 0.016	0.0GluXaa: 0.0 ± 0.0
Phe	3.058PheAla: 3.058 ± 0.022	0.617PheCys: 0.617 ± 0.009	2.377PheAsp: 2.377 ± 0.019	2.209PheGlu: 2.209 ± 0.019	1.72PhePhe: 1.72 ± 0.016	2.957PheGly: 2.957 ± 0.021	0.942PheHis: 0.942 ± 0.011	1.958PheIle: 1.958 ± 0.021	1.623PheLys: 1.623 ± 0.014	3.599PheLeu: 3.599 ± 0.029	0.845PheMet: 0.845 ± 0.013	1.49PheAsn: 1.49 ± 0.014	1.973PhePro: 1.973 ± 0.017	1.444PheGln: 1.444 ± 0.014	2.005PheArg: 2.005 ± 0.016	2.992PheSer: 2.992 ± 0.021	2.186PheThr: 2.186 ± 0.018	2.462PheVal: 2.462 ± 0.018	0.736PheTrp: 0.736 ± 0.009	1.134PheTyr: 1.134 ± 0.014	0.0PheXaa: 0.0 ± 0.0
Gly	5.205GlyAla: 5.205 ± 0.029	0.972GlyCys: 0.972 ± 0.013	3.786GlyAsp: 3.786 ± 0.025	3.666GlyGlu: 3.666 ± 0.026	2.969GlyPhe: 2.969 ± 0.023	5.466GlyGly: 5.466 ± 0.048	1.74GlyHis: 1.74 ± 0.017	3.694GlyIle: 3.694 ± 0.026	3.394GlyLys: 3.394 ± 0.027	6.241GlyLeu: 6.241 ± 0.034	1.631GlyMet: 1.631 ± 0.015	2.544GlyAsn: 2.544 ± 0.02	3.375GlyPro: 3.375 ± 0.026	2.659GlyGln: 2.659 ± 0.026	4.053GlyArg: 4.053 ± 0.027	5.626GlySer: 5.626 ± 0.037	4.037GlyThr: 4.037 ± 0.037	4.36GlyVal: 4.36 ± 0.029	1.284GlyTrp: 1.284 ± 0.012	2.174GlyTyr: 2.174 ± 0.019	0.0GlyXaa: 0.0 ± 0.0
His	1.747HisAla: 1.747 ± 0.017	0.348HisCys: 0.348 ± 0.008	1.396HisAsp: 1.396 ± 0.015	1.351HisGlu: 1.351 ± 0.015	0.955HisPhe: 0.955 ± 0.012	1.784HisGly: 1.784 ± 0.02	0.872HisHis: 0.872 ± 0.014	1.235HisIle: 1.235 ± 0.013	0.931HisLys: 0.931 ± 0.011	2.352HisLeu: 2.352 ± 0.019	0.499HisMet: 0.499 ± 0.008	0.801HisAsn: 0.801 ± 0.012	1.578HisPro: 1.578 ± 0.014	1.014HisGln: 1.014 ± 0.015	1.514HisArg: 1.514 ± 0.016	1.689HisSer: 1.689 ± 0.017	1.18HisThr: 1.18 ± 0.015	1.49HisVal: 1.49 ± 0.015	0.382HisTrp: 0.382 ± 0.008	0.689HisTyr: 0.689 ± 0.012	0.0HisXaa: 0.0 ± 0.0
Ile	4.152IleAla: 4.152 ± 0.026	0.813IleCys: 0.813 ± 0.011	2.961IleAsp: 2.961 ± 0.022	2.962IleGlu: 2.962 ± 0.026	2.072IlePhe: 2.072 ± 0.02	3.334IleGly: 3.334 ± 0.025	1.203IleHis: 1.203 ± 0.012	2.681IleIle: 2.681 ± 0.028	2.263IleLys: 2.263 ± 0.018	4.675IleLeu: 4.675 ± 0.029	1.102IleMet: 1.102 ± 0.012	1.871IleAsn: 1.871 ± 0.016	3.012IlePro: 3.012 ± 0.021	1.946IleGln: 1.946 ± 0.015	2.847IleArg: 2.847 ± 0.02	3.786IleSer: 3.786 ± 0.023	2.954IleThr: 2.954 ± 0.038	3.232IleVal: 3.232 ± 0.021	0.814IleTrp: 0.814 ± 0.011	1.423IleTyr: 1.423 ± 0.015	0.0IleXaa: 0.0 ± 0.0
Lys	4.318LysAla: 4.318 ± 0.032	0.554LysCys: 0.554 ± 0.01	2.956LysAsp: 2.956 ± 0.025	3.368LysGlu: 3.368 ± 0.027	1.512LysPhe: 1.512 ± 0.015	3.031LysGly: 3.031 ± 0.022	1.164LysHis: 1.164 ± 0.012	2.23LysIle: 2.23 ± 0.018	3.182LysLys: 3.182 ± 0.036	4.105LysLeu: 4.105 ± 0.026	1.057LysMet: 1.057 ± 0.011	1.731LysAsn: 1.731 ± 0.018	2.821LysPro: 2.821 ± 0.025	1.744LysGln: 1.744 ± 0.02	3.186LysArg: 3.186 ± 0.026	3.349LysSer: 3.349 ± 0.023	2.963LysThr: 2.963 ± 0.019	2.886LysVal: 2.886 ± 0.025	0.735LysTrp: 0.735 ± 0.011	1.348LysTyr: 1.348 ± 0.014	0.0LysXaa: 0.0 ± 0.0
Leu	7.926LeuAla: 7.926 ± 0.039	1.322LeuCys: 1.322 ± 0.013	5.43LeuAsp: 5.43 ± 0.031	5.692LeuGlu: 5.692 ± 0.039	3.466LeuPhe: 3.466 ± 0.025	6.206LeuGly: 6.206 ± 0.032	2.199LeuHis: 2.199 ± 0.019	4.081LeuIle: 4.081 ± 0.028	4.178LeuLys: 4.178 ± 0.028	8.384LeuLeu: 8.384 ± 0.055	1.874LeuMet: 1.874 ± 0.017	3.118LeuAsn: 3.118 ± 0.022	5.325LeuPro: 5.325 ± 0.029	3.711LeuGln: 3.711 ± 0.023	5.627LeuArg: 5.627 ± 0.034	7.155LeuSer: 7.155 ± 0.036	4.832LeuThr: 4.832 ± 0.026	5.674LeuVal: 5.674 ± 0.034	1.33LeuTrp: 1.33 ± 0.017	2.372LeuTyr: 2.372 ± 0.019	0.0LeuXaa: 0.0 ± 0.0
Met	2.403MetAla: 2.403 ± 0.015	0.272MetCys: 0.272 ± 0.006	1.324MetAsp: 1.324 ± 0.014	1.311MetGlu: 1.311 ± 0.014	0.788MetPhe: 0.788 ± 0.012	1.527MetGly: 1.527 ± 0.016	0.477MetHis: 0.477 ± 0.007	1.064MetIle: 1.064 ± 0.013	1.01MetLys: 1.01 ± 0.012	1.886MetLeu: 1.886 ± 0.015	0.637MetMet: 0.637 ± 0.009	0.795MetAsn: 0.795 ± 0.01	1.339MetPro: 1.339 ± 0.014	0.796MetGln: 0.796 ± 0.011	1.258MetArg: 1.258 ± 0.014	1.926MetSer: 1.926 ± 0.017	1.397MetThr: 1.397 ± 0.013	1.39MetVal: 1.39 ± 0.015	0.298MetTrp: 0.298 ± 0.007	0.531MetTyr: 0.531 ± 0.009	0.0MetXaa: 0.0 ± 0.0
Asn	2.895AsnAla: 2.895 ± 0.023	0.485AsnCys: 0.485 ± 0.01	1.986AsnAsp: 1.986 ± 0.017	1.99AsnGlu: 1.99 ± 0.018	1.35AsnPhe: 1.35 ± 0.016	2.87AsnGly: 2.87 ± 0.024	0.847AsnHis: 0.847 ± 0.01	1.978AsnIle: 1.978 ± 0.016	1.623AsnLys: 1.623 ± 0.016	3.276AsnLeu: 3.276 ± 0.023	0.879AsnMet: 0.879 ± 0.011	1.464AsnAsn: 1.464 ± 0.019	2.432AsnPro: 2.432 ± 0.017	1.309AsnGln: 1.309 ± 0.015	1.867AsnArg: 1.867 ± 0.016	2.583AsnSer: 2.583 ± 0.018	2.101AsnThr: 2.101 ± 0.017	2.252AsnVal: 2.252 ± 0.017	0.597AsnTrp: 0.597 ± 0.008	1.043AsnTyr: 1.043 ± 0.011	0.0AsnXaa: 0.0 ± 0.0
Pro	4.939ProAla: 4.939 ± 0.047	0.584ProCys: 0.584 ± 0.01	3.414ProAsp: 3.414 ± 0.021	4.164ProGlu: 4.164 ± 0.032	2.104ProPhe: 2.104 ± 0.019	4.021ProGly: 4.021 ± 0.041	1.269ProHis: 1.269 ± 0.014	2.583ProIle: 2.583 ± 0.019	2.737ProLys: 2.737 ± 0.021	4.665ProLeu: 4.665 ± 0.028	1.103ProMet: 1.103 ± 0.012	2.132ProAsn: 2.132 ± 0.017	4.705ProPro: 4.705 ± 0.057	2.402ProGln: 2.402 ± 0.028	3.37ProArg: 3.37 ± 0.026	5.628ProSer: 5.628 ± 0.042	3.875ProThr: 3.875 ± 0.03	3.575ProVal: 3.575 ± 0.03	0.857ProTrp: 0.857 ± 0.012	1.48ProTyr: 1.48 ± 0.016	0.0ProXaa: 0.0 ± 0.0
Gln	3.446GlnAla: 3.446 ± 0.028	0.46GlnCys: 0.46 ± 0.008	2.262GlnAsp: 2.262 ± 0.018	2.448GlnGlu: 2.448 ± 0.022	1.286GlnPhe: 1.286 ± 0.013	2.506GlnGly: 2.506 ± 0.022	1.066GlnHis: 1.066 ± 0.013	1.774GlnIle: 1.774 ± 0.015	1.836GlnLys: 1.836 ± 0.019	3.43GlnLeu: 3.43 ± 0.025	0.863GlnMet: 0.863 ± 0.011	1.403GlnAsn: 1.403 ± 0.017	2.552GlnPro: 2.552 ± 0.031	2.267GlnGln: 2.267 ± 0.045	2.503GlnArg: 2.503 ± 0.019	2.9GlnSer: 2.9 ± 0.023	2.255GlnThr: 2.255 ± 0.019	2.313GlnVal: 2.313 ± 0.021	0.595GlnTrp: 0.595 ± 0.009	1.093GlnTyr: 1.093 ± 0.012	0.0GlnXaa: 0.0 ± 0.0
Arg	4.45ArgAla: 4.45 ± 0.027	0.774ArgCys: 0.774 ± 0.01	3.52ArgAsp: 3.52 ± 0.028	3.681ArgGlu: 3.681 ± 0.027	2.196ArgPhe: 2.196 ± 0.017	3.689ArgGly: 3.689 ± 0.028	1.605ArgHis: 1.605 ± 0.017	2.849ArgIle: 2.849 ± 0.021	3.167ArgLys: 3.167 ± 0.024	5.499ArgLeu: 5.499 ± 0.033	1.293ArgMet: 1.293 ± 0.016	2.154ArgAsn: 2.154 ± 0.016	3.477ArgPro: 3.477 ± 0.028	2.573ArgGln: 2.573 ± 0.019	4.961ArgArg: 4.961 ± 0.031	4.421ArgSer: 4.421 ± 0.034	3.093ArgThr: 3.093 ± 0.02	3.438ArgVal: 3.438 ± 0.023	1.032ArgTrp: 1.032 ± 0.011	1.665ArgTyr: 1.665 ± 0.014	0.0ArgXaa: 0.0 ± 0.0
Ser	6.061SerAla: 6.061 ± 0.031	0.953SerCys: 0.953 ± 0.013	4.274SerAsp: 4.274 ± 0.032	4.15SerGlu: 4.15 ± 0.029	3.061SerPhe: 3.061 ± 0.023	5.366SerGly: 5.366 ± 0.041	1.862SerHis: 1.862 ± 0.019	4.003SerIle: 4.003 ± 0.028	3.619SerLys: 3.619 ± 0.027	7.13SerLeu: 7.13 ± 0.035	1.748SerMet: 1.748 ± 0.015	2.829SerAsn: 2.829 ± 0.02	5.12SerPro: 5.12 ± 0.04	3.137SerGln: 3.137 ± 0.021	4.847SerArg: 4.847 ± 0.036	7.965SerSer: 7.965 ± 0.06	5.344SerThr: 5.344 ± 0.037	4.484SerVal: 4.484 ± 0.026	1.276SerTrp: 1.276 ± 0.014	2.031SerTyr: 2.031 ± 0.018	0.0SerXaa: 0.0 ± 0.0
Thr	5.015ThrAla: 5.015 ± 0.032	0.84ThrCys: 0.84 ± 0.012	2.909ThrAsp: 2.909 ± 0.023	3.337ThrGlu: 3.337 ± 0.028	2.299ThrPhe: 2.299 ± 0.02	4.168ThrGly: 4.168 ± 0.029	1.241ThrHis: 1.241 ± 0.012	3.185ThrIle: 3.185 ± 0.036	2.715ThrLys: 2.715 ± 0.024	5.248ThrLeu: 5.248 ± 0.032	1.252ThrMet: 1.252 ± 0.012	2.07ThrAsn: 2.07 ± 0.018	4.195ThrPro: 4.195 ± 0.037	2.064ThrGln: 2.064 ± 0.018	3.157ThrArg: 3.157 ± 0.021	5.104ThrSer: 5.104 ± 0.037	4.4ThrThr: 4.4 ± 0.053	3.793ThrVal: 3.793 ± 0.039	0.985ThrTrp: 0.985 ± 0.011	1.623ThrTyr: 1.623 ± 0.015	0.0ThrXaa: 0.0 ± 0.0
Val	5.278ValAla: 5.278 ± 0.027	0.89ValCys: 0.89 ± 0.012	3.841ValAsp: 3.841 ± 0.025	4.02ValGlu: 4.02 ± 0.031	2.554ValPhe: 2.554 ± 0.021	4.065ValGly: 4.065 ± 0.028	1.388ValHis: 1.388 ± 0.013	3.106ValIle: 3.106 ± 0.025	2.948ValLys: 2.948 ± 0.023	5.625ValLeu: 5.625 ± 0.027	1.365ValMet: 1.365 ± 0.015	2.216ValAsn: 2.216 ± 0.018	3.607ValPro: 3.607 ± 0.027	2.34ValGln: 2.34 ± 0.019	3.369ValArg: 3.369 ± 0.024	4.631ValSer: 4.631 ± 0.025	3.666ValThr: 3.666 ± 0.035	4.447ValVal: 4.447 ± 0.03	0.933ValTrp: 0.933 ± 0.012	1.775ValTyr: 1.775 ± 0.018	0.0ValXaa: 0.0 ± 0.0
Trp	1.291TrpAla: 1.291 ± 0.014	0.23TrpCys: 0.23 ± 0.006	0.973TrpAsp: 0.973 ± 0.011	0.944TrpGlu: 0.944 ± 0.011	0.629TrpPhe: 0.629 ± 0.009	1.045TrpGly: 1.045 ± 0.014	0.399TrpHis: 0.399 ± 0.008	0.873TrpIle: 0.873 ± 0.011	0.886TrpLys: 0.886 ± 0.013	1.511TrpLeu: 1.511 ± 0.014	0.41TrpMet: 0.41 ± 0.008	0.67TrpAsn: 0.67 ± 0.009	0.705TrpPro: 0.705 ± 0.01	0.609TrpGln: 0.609 ± 0.01	1.014TrpArg: 1.014 ± 0.011	1.154TrpSer: 1.154 ± 0.012	1.049TrpThr: 1.049 ± 0.012	0.988TrpVal: 0.988 ± 0.011	0.319TrpTrp: 0.319 ± 0.007	0.475TrpTyr: 0.475 ± 0.008	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.078TyrAla: 2.078 ± 0.017	0.464TyrCys: 0.464 ± 0.009	1.665TyrAsp: 1.665 ± 0.017	1.555TyrGlu: 1.555 ± 0.015	1.211TyrPhe: 1.211 ± 0.014	2.108TyrGly: 2.108 ± 0.021	0.774TyrHis: 0.774 ± 0.01	1.393TyrIle: 1.393 ± 0.015	1.135TyrLys: 1.135 ± 0.012	2.654TyrLeu: 2.654 ± 0.022	0.635TyrMet: 0.635 ± 0.01	1.089TyrAsn: 1.089 ± 0.01	1.462TyrPro: 1.462 ± 0.017	1.112TyrGln: 1.112 ± 0.014	1.633TyrArg: 1.633 ± 0.017	1.966TyrSer: 1.966 ± 0.015	1.591TyrThr: 1.591 ± 0.018	1.645TyrVal: 1.645 ± 0.018	0.495TyrTrp: 0.495 ± 0.008	0.916TyrTyr: 0.916 ± 0.012	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 16484 proteins (7632786 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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