Amino acid dipepetide frequency for Hubei sobemo-like virus 34

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
2.938AlaAla: 2.938 ± 0.054
0.0AlaCys: 0.0 ± 0.0
2.938AlaAsp: 2.938 ± 1.559
3.918AlaGlu: 3.918 ± 0.574
1.959AlaPhe: 1.959 ± 1.04
2.938AlaGly: 2.938 ± 0.054
0.979AlaHis: 0.979 ± 0.52
2.938AlaIle: 2.938 ± 1.452
2.938AlaLys: 2.938 ± 1.559
1.959AlaLeu: 1.959 ± 0.466
1.959AlaMet: 1.959 ± 0.466
0.0AlaAsn: 0.0 ± 0.0
0.0AlaPro: 0.0 ± 0.0
0.0AlaGln: 0.0 ± 0.0
2.938AlaArg: 2.938 ± 1.559
1.959AlaSer: 1.959 ± 0.466
0.979AlaThr: 0.979 ± 0.52
0.979AlaVal: 0.979 ± 0.52
0.0AlaTrp: 0.0 ± 0.0
4.897AlaTyr: 4.897 ± 0.412
0.0AlaXaa: 0.0 ± 0.0
Cys
0.979CysAla: 0.979 ± 0.52
0.0CysCys: 0.0 ± 0.0
0.979CysAsp: 0.979 ± 0.52
0.979CysGlu: 0.979 ± 0.52
0.0CysPhe: 0.0 ± 0.0
0.0CysGly: 0.0 ± 0.0
0.979CysHis: 0.979 ± 0.986
1.959CysIle: 1.959 ± 0.466
0.0CysLys: 0.0 ± 0.0
0.979CysLeu: 0.979 ± 0.52
0.0CysMet: 0.0 ± 0.611
0.979CysAsn: 0.979 ± 0.986
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
0.0CysArg: 0.0 ± 0.0
0.0CysSer: 0.0 ± 0.0
0.0CysThr: 0.0 ± 0.0
2.938CysVal: 2.938 ± 1.452
0.0CysTrp: 0.0 ± 0.0
1.959CysTyr: 1.959 ± 1.04
0.0CysXaa: 0.0 ± 0.0
Asp
1.959AspAla: 1.959 ± 0.466
0.0AspCys: 0.0 ± 0.0
1.959AspAsp: 1.959 ± 0.466
0.0AspGlu: 0.0 ± 0.0
3.918AspPhe: 3.918 ± 0.574
2.938AspGly: 2.938 ± 1.452
3.918AspHis: 3.918 ± 0.932
1.959AspIle: 1.959 ± 0.466
5.877AspLys: 5.877 ± 0.108
4.897AspLeu: 4.897 ± 1.093
1.959AspMet: 1.959 ± 1.04
3.918AspAsn: 3.918 ± 2.438
1.959AspPro: 1.959 ± 0.466
2.938AspGln: 2.938 ± 1.452
0.979AspArg: 0.979 ± 0.52
1.959AspSer: 1.959 ± 0.466
0.979AspThr: 0.979 ± 0.52
0.979AspVal: 0.979 ± 0.986
1.959AspTrp: 1.959 ± 1.972
1.959AspTyr: 1.959 ± 0.466
0.0AspXaa: 0.0 ± 0.0
Glu
1.959GluAla: 1.959 ± 1.04
1.959GluCys: 1.959 ± 0.466
2.938GluAsp: 2.938 ± 1.559
5.877GluGlu: 5.877 ± 1.613
4.897GluPhe: 4.897 ± 0.412
2.938GluGly: 2.938 ± 1.559
0.0GluHis: 0.0 ± 0.0
3.918GluIle: 3.918 ± 0.932
3.918GluLys: 3.918 ± 2.079
7.835GluLeu: 7.835 ± 1.864
2.938GluMet: 2.938 ± 1.559
1.959GluAsn: 1.959 ± 1.04
4.897GluPro: 4.897 ± 0.412
0.979GluGln: 0.979 ± 0.52
0.979GluArg: 0.979 ± 0.986
7.835GluSer: 7.835 ± 2.653
3.918GluThr: 3.918 ± 0.574
2.938GluVal: 2.938 ± 0.054
0.979GluTrp: 0.979 ± 0.986
1.959GluTyr: 1.959 ± 0.466
0.0GluXaa: 0.0 ± 0.0
Phe
0.979PheAla: 0.979 ± 0.986
0.0PheCys: 0.0 ± 0.0
1.959PheAsp: 1.959 ± 1.972
2.938PheGlu: 2.938 ± 0.054
0.979PhePhe: 0.979 ± 0.52
1.959PheGly: 1.959 ± 0.466
0.979PheHis: 0.979 ± 0.52
5.877PheIle: 5.877 ± 0.108
1.959PheLys: 1.959 ± 0.466
0.979PheLeu: 0.979 ± 0.52
1.959PheMet: 1.959 ± 1.04
0.979PheAsn: 0.979 ± 0.52
2.938PhePro: 2.938 ± 1.559
2.938PheGln: 2.938 ± 1.452
2.938PheArg: 2.938 ± 1.452
0.979PheSer: 0.979 ± 0.52
3.918PheThr: 3.918 ± 0.932
3.918PheVal: 3.918 ± 0.574
0.979PheTrp: 0.979 ± 0.52
0.979PheTyr: 0.979 ± 0.986
0.0PheXaa: 0.0 ± 0.0
Gly
1.959GlyAla: 1.959 ± 1.04
1.959GlyCys: 1.959 ± 1.972
2.938GlyAsp: 2.938 ± 0.054
3.918GlyGlu: 3.918 ± 0.574
2.938GlyPhe: 2.938 ± 1.559
2.938GlyGly: 2.938 ± 1.452
1.959GlyHis: 1.959 ± 0.466
3.918GlyIle: 3.918 ± 0.932
3.918GlyLys: 3.918 ± 0.574
4.897GlyLeu: 4.897 ± 1.093
1.959GlyMet: 1.959 ± 0.466
1.959GlyAsn: 1.959 ± 1.04
2.938GlyPro: 2.938 ± 0.054
0.979GlyGln: 0.979 ± 0.986
0.979GlyArg: 0.979 ± 0.52
4.897GlySer: 4.897 ± 2.599
3.918GlyThr: 3.918 ± 2.079
6.856GlyVal: 6.856 ± 0.627
2.938GlyTrp: 2.938 ± 1.452
1.959GlyTyr: 1.959 ± 0.466
0.0GlyXaa: 0.0 ± 0.0
His
0.979HisAla: 0.979 ± 0.986
0.979HisCys: 0.979 ± 0.986
0.979HisAsp: 0.979 ± 0.52
0.0HisGlu: 0.0 ± 0.0
0.979HisPhe: 0.979 ± 0.52
0.979HisGly: 0.979 ± 0.986
0.0HisHis: 0.0 ± 0.0
0.979HisIle: 0.979 ± 0.52
2.938HisLys: 2.938 ± 0.054
1.959HisLeu: 1.959 ± 1.04
2.938HisMet: 2.938 ± 2.957
0.0HisAsn: 0.0 ± 0.0
0.0HisPro: 0.0 ± 0.0
2.938HisGln: 2.938 ± 0.054
1.959HisArg: 1.959 ± 1.972
1.959HisSer: 1.959 ± 1.04
0.0HisThr: 0.0 ± 0.0
1.959HisVal: 1.959 ± 0.466
0.0HisTrp: 0.0 ± 0.0
1.959HisTyr: 1.959 ± 0.466
0.0HisXaa: 0.0 ± 0.0
Ile
3.918IleAla: 3.918 ± 0.574
0.0IleCys: 0.0 ± 0.0
5.877IleAsp: 5.877 ± 1.398
4.897IleGlu: 4.897 ± 0.412
3.918IlePhe: 3.918 ± 0.932
5.877IleGly: 5.877 ± 1.613
0.979IleHis: 0.979 ± 0.52
6.856IleIle: 6.856 ± 0.878
5.877IleLys: 5.877 ± 1.613
8.815IleLeu: 8.815 ± 3.173
4.897IleMet: 4.897 ± 1.918
1.959IleAsn: 1.959 ± 1.04
5.877IlePro: 5.877 ± 1.613
0.0IleGln: 0.0 ± 0.0
2.938IleArg: 2.938 ± 1.452
1.959IleSer: 1.959 ± 1.972
0.0IleThr: 0.0 ± 0.0
2.938IleVal: 2.938 ± 0.054
1.959IleTrp: 1.959 ± 1.04
1.959IleTyr: 1.959 ± 1.04
0.0IleXaa: 0.0 ± 0.0
Lys
1.959LysAla: 1.959 ± 1.972
0.979LysCys: 0.979 ± 0.52
1.959LysAsp: 1.959 ± 1.972
5.877LysGlu: 5.877 ± 1.613
3.918LysPhe: 3.918 ± 0.932
3.918LysGly: 3.918 ± 0.932
2.938LysHis: 2.938 ± 1.452
6.856LysIle: 6.856 ± 2.133
9.794LysLys: 9.794 ± 0.824
6.856LysLeu: 6.856 ± 0.878
2.938LysMet: 2.938 ± 0.054
3.918LysAsn: 3.918 ± 0.932
8.815LysPro: 8.815 ± 3.173
4.897LysGln: 4.897 ± 2.599
0.979LysArg: 0.979 ± 0.986
4.897LysSer: 4.897 ± 3.423
3.918LysThr: 3.918 ± 2.079
3.918LysVal: 3.918 ± 0.574
0.979LysTrp: 0.979 ± 0.986
4.897LysTyr: 4.897 ± 2.599
0.0LysXaa: 0.0 ± 0.0
Leu
4.897LeuAla: 4.897 ± 0.412
0.979LeuCys: 0.979 ± 0.986
1.959LeuAsp: 1.959 ± 1.972
9.794LeuGlu: 9.794 ± 0.681
5.877LeuPhe: 5.877 ± 2.904
2.938LeuGly: 2.938 ± 1.559
2.938LeuHis: 2.938 ± 1.452
4.897LeuIle: 4.897 ± 0.412
6.856LeuLys: 6.856 ± 2.133
8.815LeuLeu: 8.815 ± 1.344
3.918LeuMet: 3.918 ± 0.574
3.918LeuAsn: 3.918 ± 0.574
2.938LeuPro: 2.938 ± 0.054
3.918LeuGln: 3.918 ± 0.574
4.897LeuArg: 4.897 ± 3.423
0.979LeuSer: 0.979 ± 0.52
2.938LeuThr: 2.938 ± 1.559
9.794LeuVal: 9.794 ± 0.681
0.979LeuTrp: 0.979 ± 0.52
5.877LeuTyr: 5.877 ± 2.904
0.0LeuXaa: 0.0 ± 0.0
Met
1.959MetAla: 1.959 ± 0.466
0.979MetCys: 0.979 ± 0.52
1.959MetAsp: 1.959 ± 1.04
0.979MetGlu: 0.979 ± 0.986
0.0MetPhe: 0.0 ± 0.0
1.959MetGly: 1.959 ± 0.466
0.979MetHis: 0.979 ± 0.52
1.959MetIle: 1.959 ± 1.04
1.959MetLys: 1.959 ± 0.466
1.959MetLeu: 1.959 ± 0.466
0.979MetMet: 0.979 ± 0.52
0.979MetAsn: 0.979 ± 0.986
3.918MetPro: 3.918 ± 0.574
0.979MetGln: 0.979 ± 0.986
0.979MetArg: 0.979 ± 0.52
3.918MetSer: 3.918 ± 0.574
1.959MetThr: 1.959 ± 1.04
3.918MetVal: 3.918 ± 0.932
0.979MetTrp: 0.979 ± 0.986
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
0.979AsnAla: 0.979 ± 0.52
0.0AsnCys: 0.0 ± 0.0
1.959AsnAsp: 1.959 ± 1.04
0.979AsnGlu: 0.979 ± 0.986
0.979AsnPhe: 0.979 ± 0.986
0.979AsnGly: 0.979 ± 0.986
1.959AsnHis: 1.959 ± 0.466
0.979AsnIle: 0.979 ± 0.52
5.877AsnLys: 5.877 ± 2.904
1.959AsnLeu: 1.959 ± 0.466
2.938AsnMet: 2.938 ± 1.348
0.979AsnAsn: 0.979 ± 0.986
3.918AsnPro: 3.918 ± 0.574
0.0AsnGln: 0.0 ± 0.0
1.959AsnArg: 1.959 ± 0.466
5.877AsnSer: 5.877 ± 0.108
1.959AsnThr: 1.959 ± 0.466
1.959AsnVal: 1.959 ± 1.04
1.959AsnTrp: 1.959 ± 0.466
1.959AsnTyr: 1.959 ± 0.466
0.0AsnXaa: 0.0 ± 0.0
Pro
0.979ProAla: 0.979 ± 0.52
0.0ProCys: 0.0 ± 0.0
1.959ProAsp: 1.959 ± 1.04
6.856ProGlu: 6.856 ± 2.133
1.959ProPhe: 1.959 ± 1.04
5.877ProGly: 5.877 ± 1.613
0.979ProHis: 0.979 ± 0.986
1.959ProIle: 1.959 ± 0.466
4.897ProLys: 4.897 ± 2.599
5.877ProLeu: 5.877 ± 1.398
0.0ProMet: 0.0 ± 0.0
3.918ProAsn: 3.918 ± 0.574
2.938ProPro: 2.938 ± 0.054
1.959ProGln: 1.959 ± 1.04
2.938ProArg: 2.938 ± 1.559
5.877ProSer: 5.877 ± 1.613
1.959ProThr: 1.959 ± 0.466
6.856ProVal: 6.856 ± 0.878
0.0ProTrp: 0.0 ± 0.0
2.938ProTyr: 2.938 ± 0.054
0.0ProXaa: 0.0 ± 0.0
Gln
3.918GlnAla: 3.918 ± 2.079
0.979GlnCys: 0.979 ± 0.52
1.959GlnAsp: 1.959 ± 1.972
2.938GlnGlu: 2.938 ± 0.054
0.979GlnPhe: 0.979 ± 0.986
1.959GlnGly: 1.959 ± 1.04
0.0GlnHis: 0.0 ± 0.0
3.918GlnIle: 3.918 ± 0.574
3.918GlnLys: 3.918 ± 0.574
5.877GlnLeu: 5.877 ± 1.398
0.0GlnMet: 0.0 ± 0.0
0.979GlnAsn: 0.979 ± 0.52
2.938GlnPro: 2.938 ± 0.054
0.979GlnGln: 0.979 ± 0.52
0.979GlnArg: 0.979 ± 0.52
0.979GlnSer: 0.979 ± 0.52
0.979GlnThr: 0.979 ± 0.986
0.979GlnVal: 0.979 ± 0.52
0.0GlnTrp: 0.0 ± 0.0
0.0GlnTyr: 0.0 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
0.0ArgAla: 0.0 ± 0.0
0.979ArgCys: 0.979 ± 0.52
0.979ArgAsp: 0.979 ± 0.986
1.959ArgGlu: 1.959 ± 1.04
1.959ArgPhe: 1.959 ± 0.466
1.959ArgGly: 1.959 ± 1.04
1.959ArgHis: 1.959 ± 1.04
1.959ArgIle: 1.959 ± 0.466
3.918ArgLys: 3.918 ± 0.574
6.856ArgLeu: 6.856 ± 5.395
0.0ArgMet: 0.0 ± 0.0
0.979ArgAsn: 0.979 ± 0.52
0.979ArgPro: 0.979 ± 0.52
0.979ArgGln: 0.979 ± 0.986
1.959ArgArg: 1.959 ± 1.04
2.938ArgSer: 2.938 ± 0.054
0.979ArgThr: 0.979 ± 0.52
3.918ArgVal: 3.918 ± 0.574
0.979ArgTrp: 0.979 ± 0.52
2.938ArgTyr: 2.938 ± 1.452
0.0ArgXaa: 0.0 ± 0.0
Ser
1.959SerAla: 1.959 ± 1.04
0.0SerCys: 0.0 ± 0.0
3.918SerAsp: 3.918 ± 0.574
1.959SerGlu: 1.959 ± 0.466
1.959SerPhe: 1.959 ± 0.466
4.897SerGly: 4.897 ± 0.412
0.0SerHis: 0.0 ± 0.0
6.856SerIle: 6.856 ± 2.133
4.897SerLys: 4.897 ± 0.412
6.856SerLeu: 6.856 ± 0.627
0.0SerMet: 0.0 ± 0.0
2.938SerAsn: 2.938 ± 1.559
4.897SerPro: 4.897 ± 1.918
1.959SerGln: 1.959 ± 0.466
0.0SerArg: 0.0 ± 0.0
6.856SerSer: 6.856 ± 0.878
7.835SerThr: 7.835 ± 1.147
6.856SerVal: 6.856 ± 0.627
0.979SerTrp: 0.979 ± 0.986
2.938SerTyr: 2.938 ± 1.452
0.0SerXaa: 0.0 ± 0.0
Thr
0.979ThrAla: 0.979 ± 0.52
0.979ThrCys: 0.979 ± 0.52
2.938ThrAsp: 2.938 ± 0.054
2.938ThrGlu: 2.938 ± 0.054
0.0ThrPhe: 0.0 ± 0.0
3.918ThrGly: 3.918 ± 0.574
0.979ThrHis: 0.979 ± 0.986
0.979ThrIle: 0.979 ± 0.52
5.877ThrLys: 5.877 ± 1.398
2.938ThrLeu: 2.938 ± 0.054
0.979ThrMet: 0.979 ± 0.52
1.959ThrAsn: 1.959 ± 1.972
6.856ThrPro: 6.856 ± 3.639
3.918ThrGln: 3.918 ± 2.079
2.938ThrArg: 2.938 ± 1.559
4.897ThrSer: 4.897 ± 1.093
2.938ThrThr: 2.938 ± 0.054
5.877ThrVal: 5.877 ± 1.613
0.0ThrTrp: 0.0 ± 0.0
0.0ThrTyr: 0.0 ± 0.0
0.0ThrXaa: 0.0 ± 0.0
Val
0.979ValAla: 0.979 ± 0.52
1.959ValCys: 1.959 ± 1.04
3.918ValAsp: 3.918 ± 2.438
5.877ValGlu: 5.877 ± 3.119
1.959ValPhe: 1.959 ± 0.466
7.835ValGly: 7.835 ± 0.358
0.979ValHis: 0.979 ± 0.52
7.835ValIle: 7.835 ± 2.653
3.918ValLys: 3.918 ± 2.438
3.918ValLeu: 3.918 ± 2.079
0.979ValMet: 0.979 ± 0.986
2.938ValAsn: 2.938 ± 1.452
2.938ValPro: 2.938 ± 0.054
2.938ValGln: 2.938 ± 1.559
3.918ValArg: 3.918 ± 0.574
6.856ValSer: 6.856 ± 2.384
6.856ValThr: 6.856 ± 0.627
5.877ValVal: 5.877 ± 1.398
1.959ValTrp: 1.959 ± 0.466
0.0ValTyr: 0.0 ± 0.0
0.0ValXaa: 0.0 ± 0.0
Trp
1.959TrpAla: 1.959 ± 1.04
0.0TrpCys: 0.0 ± 0.0
0.979TrpAsp: 0.979 ± 0.986
0.979TrpGlu: 0.979 ± 0.986
0.0TrpPhe: 0.0 ± 0.0
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
1.959TrpIle: 1.959 ± 0.466
0.979TrpLys: 0.979 ± 0.986
1.959TrpLeu: 1.959 ± 1.972
0.979TrpMet: 0.979 ± 0.52
2.938TrpAsn: 2.938 ± 1.452
0.979TrpPro: 0.979 ± 0.52
0.0TrpGln: 0.0 ± 0.0
0.0TrpArg: 0.0 ± 0.0
1.959TrpSer: 1.959 ± 0.466
1.959TrpThr: 1.959 ± 0.466
0.0TrpVal: 0.0 ± 0.0
1.959TrpTrp: 1.959 ± 0.466
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.979TyrAla: 0.979 ± 0.52
0.979TyrCys: 0.979 ± 0.986
1.959TyrAsp: 1.959 ± 1.972
1.959TyrGlu: 1.959 ± 0.466
1.959TyrPhe: 1.959 ± 1.04
3.918TyrGly: 3.918 ± 2.079
0.979TyrHis: 0.979 ± 0.986
2.938TyrIle: 2.938 ± 0.054
4.897TyrLys: 4.897 ± 1.918
3.918TyrLeu: 3.918 ± 0.932
0.0TyrMet: 0.0 ± 0.0
1.959TyrAsn: 1.959 ± 0.466
0.0TyrPro: 0.0 ± 0.0
1.959TyrGln: 1.959 ± 0.466
3.918TyrArg: 3.918 ± 0.574
0.979TyrSer: 0.979 ± 0.986
4.897TyrThr: 4.897 ± 1.093
0.979TyrVal: 0.979 ± 0.986
0.0TyrTrp: 0.0 ± 0.0
0.979TyrTyr: 0.979 ± 0.52
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (1022 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski