Amino acid dipepetide frequency for Tenacibaculum jejuense

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.162AlaAla: 3.162 ± 0.061
0.487AlaCys: 0.487 ± 0.026
2.893AlaAsp: 2.893 ± 0.078
3.386AlaGlu: 3.386 ± 0.06
2.932AlaPhe: 2.932 ± 0.049
3.519AlaGly: 3.519 ± 0.096
0.897AlaHis: 0.897 ± 0.028
4.954AlaIle: 4.954 ± 0.074
4.529AlaLys: 4.529 ± 0.077
5.357AlaLeu: 5.357 ± 0.075
1.14AlaMet: 1.14 ± 0.033
3.36AlaAsn: 3.36 ± 0.059
1.676AlaPro: 1.676 ± 0.058
1.97AlaGln: 1.97 ± 0.04
1.705AlaArg: 1.705 ± 0.039
3.935AlaSer: 3.935 ± 0.069
3.59AlaThr: 3.59 ± 0.115
3.536AlaVal: 3.536 ± 0.052
0.53AlaTrp: 0.53 ± 0.025
2.18AlaTyr: 2.18 ± 0.041
0.0AlaXaa: 0.0 ± 0.0
Cys
0.373CysAla: 0.373 ± 0.016
0.102CysCys: 0.102 ± 0.01
0.426CysAsp: 0.426 ± 0.019
0.472CysGlu: 0.472 ± 0.018
0.442CysPhe: 0.442 ± 0.018
0.554CysGly: 0.554 ± 0.022
0.164CysHis: 0.164 ± 0.014
0.624CysIle: 0.624 ± 0.027
0.555CysLys: 0.555 ± 0.021
0.579CysLeu: 0.579 ± 0.021
0.124CysMet: 0.124 ± 0.012
0.514CysAsn: 0.514 ± 0.028
0.261CysPro: 0.261 ± 0.016
0.184CysGln: 0.184 ± 0.012
0.196CysArg: 0.196 ± 0.012
0.659CysSer: 0.659 ± 0.043
0.431CysThr: 0.431 ± 0.02
0.402CysVal: 0.402 ± 0.018
0.063CysTrp: 0.063 ± 0.007
0.3CysTyr: 0.3 ± 0.016
0.0CysXaa: 0.0 ± 0.0
Asp
3.301AspAla: 3.301 ± 0.079
0.429AspCys: 0.429 ± 0.019
2.904AspAsp: 2.904 ± 0.062
3.716AspGlu: 3.716 ± 0.061
3.855AspPhe: 3.855 ± 0.062
3.634AspGly: 3.634 ± 0.088
0.892AspHis: 0.892 ± 0.026
4.535AspIle: 4.535 ± 0.068
4.371AspLys: 4.371 ± 0.071
5.278AspLeu: 5.278 ± 0.077
0.854AspMet: 0.854 ± 0.027
3.48AspAsn: 3.48 ± 0.055
1.694AspPro: 1.694 ± 0.088
1.618AspGln: 1.618 ± 0.055
1.835AspArg: 1.835 ± 0.041
3.216AspSer: 3.216 ± 0.07
2.96AspThr: 2.96 ± 0.07
3.623AspVal: 3.623 ± 0.075
0.698AspTrp: 0.698 ± 0.028
2.77AspTyr: 2.77 ± 0.051
0.0AspXaa: 0.0 ± 0.0
Glu
3.842GluAla: 3.842 ± 0.063
0.342GluCys: 0.342 ± 0.017
3.688GluAsp: 3.688 ± 0.061
5.199GluGlu: 5.199 ± 0.089
3.185GluPhe: 3.185 ± 0.05
3.549GluGly: 3.549 ± 0.065
1.039GluHis: 1.039 ± 0.03
5.991GluIle: 5.991 ± 0.076
6.459GluLys: 6.459 ± 0.09
6.486GluLeu: 6.486 ± 0.099
1.318GluMet: 1.318 ± 0.032
5.175GluAsn: 5.175 ± 0.077
1.362GluPro: 1.362 ± 0.037
2.066GluGln: 2.066 ± 0.043
2.354GluArg: 2.354 ± 0.045
3.265GluSer: 3.265 ± 0.05
3.68GluThr: 3.68 ± 0.062
4.427GluVal: 4.427 ± 0.066
0.598GluTrp: 0.598 ± 0.02
2.521GluTyr: 2.521 ± 0.046
0.0GluXaa: 0.0 ± 0.0
Phe
2.569PheAla: 2.569 ± 0.053
0.406PheCys: 0.406 ± 0.018
3.386PheAsp: 3.386 ± 0.059
3.391PheGlu: 3.391 ± 0.055
3.024PhePhe: 3.024 ± 0.066
3.412PheGly: 3.412 ± 0.06
0.836PheHis: 0.836 ± 0.027
4.293PheIle: 4.293 ± 0.074
4.294PheLys: 4.294 ± 0.071
4.973PheLeu: 4.973 ± 0.084
0.961PheMet: 0.961 ± 0.03
3.787PheAsn: 3.787 ± 0.062
1.636PhePro: 1.636 ± 0.04
1.536PheGln: 1.536 ± 0.041
1.63PheArg: 1.63 ± 0.04
4.51PheSer: 4.51 ± 0.065
3.426PheThr: 3.426 ± 0.08
2.957PheVal: 2.957 ± 0.047
0.592PheTrp: 0.592 ± 0.021
2.342PheTyr: 2.342 ± 0.048
0.0PheXaa: 0.0 ± 0.0
Gly
3.644GlyAla: 3.644 ± 0.081
0.579GlyCys: 0.579 ± 0.033
3.399GlyAsp: 3.399 ± 0.097
3.529GlyGlu: 3.529 ± 0.063
3.545GlyPhe: 3.545 ± 0.062
4.409GlyGly: 4.409 ± 0.099
0.901GlyHis: 0.901 ± 0.03
5.173GlyIle: 5.173 ± 0.068
5.008GlyLys: 5.008 ± 0.085
5.166GlyLeu: 5.166 ± 0.071
1.252GlyMet: 1.252 ± 0.037
4.017GlyAsn: 4.017 ± 0.092
1.165GlyPro: 1.165 ± 0.042
1.58GlyGln: 1.58 ± 0.037
1.953GlyArg: 1.953 ± 0.038
3.967GlySer: 3.967 ± 0.109
4.003GlyThr: 4.003 ± 0.123
4.158GlyVal: 4.158 ± 0.069
0.67GlyTrp: 0.67 ± 0.028
2.624GlyTyr: 2.624 ± 0.047
0.0GlyXaa: 0.0 ± 0.0
His
0.803HisAla: 0.803 ± 0.027
0.168HisCys: 0.168 ± 0.009
0.8HisAsp: 0.8 ± 0.028
1.019HisGlu: 1.019 ± 0.029
1.049HisPhe: 1.049 ± 0.031
0.927HisGly: 0.927 ± 0.027
0.45HisHis: 0.45 ± 0.023
1.393HisIle: 1.393 ± 0.035
1.347HisLys: 1.347 ± 0.04
1.676HisLeu: 1.676 ± 0.041
0.271HisMet: 0.271 ± 0.014
1.042HisAsn: 1.042 ± 0.031
0.728HisPro: 0.728 ± 0.026
0.68HisGln: 0.68 ± 0.021
0.606HisArg: 0.606 ± 0.022
0.955HisSer: 0.955 ± 0.029
0.902HisThr: 0.902 ± 0.03
0.893HisVal: 0.893 ± 0.027
0.188HisTrp: 0.188 ± 0.014
0.729HisTyr: 0.729 ± 0.027
0.0HisXaa: 0.0 ± 0.0
Ile
5.092IleAla: 5.092 ± 0.069
0.637IleCys: 0.637 ± 0.028
5.119IleAsp: 5.119 ± 0.065
5.721IleGlu: 5.721 ± 0.074
3.842IlePhe: 3.842 ± 0.068
4.657IleGly: 4.657 ± 0.073
1.476IleHis: 1.476 ± 0.038
6.345IleIle: 6.345 ± 0.094
6.611IleLys: 6.611 ± 0.096
7.141IleLeu: 7.141 ± 0.113
1.175IleMet: 1.175 ± 0.035
5.552IleAsn: 5.552 ± 0.073
3.226IlePro: 3.226 ± 0.054
2.872IleGln: 2.872 ± 0.046
2.55IleArg: 2.55 ± 0.046
6.15IleSer: 6.15 ± 0.088
5.601IleThr: 5.601 ± 0.115
4.762IleVal: 4.762 ± 0.068
0.678IleTrp: 0.678 ± 0.024
2.879IleTyr: 2.879 ± 0.053
0.0IleXaa: 0.0 ± 0.0
Lys
4.762LysAla: 4.762 ± 0.083
0.378LysCys: 0.378 ± 0.018
4.766LysAsp: 4.766 ± 0.077
7.199LysGlu: 7.199 ± 0.108
3.292LysPhe: 3.292 ± 0.055
4.64LysGly: 4.64 ± 0.072
1.423LysHis: 1.423 ± 0.037
7.044LysIle: 7.044 ± 0.099
8.701LysLys: 8.701 ± 0.151
7.311LysLeu: 7.311 ± 0.104
1.844LysMet: 1.844 ± 0.046
6.139LysAsn: 6.139 ± 0.089
2.286LysPro: 2.286 ± 0.05
2.909LysGln: 2.909 ± 0.058
3.15LysArg: 3.15 ± 0.069
5.163LysSer: 5.163 ± 0.076
4.989LysThr: 4.989 ± 0.069
5.16LysVal: 5.16 ± 0.079
0.794LysTrp: 0.794 ± 0.026
3.327LysTyr: 3.327 ± 0.053
0.0LysXaa: 0.0 ± 0.0
Leu
5.087LeuAla: 5.087 ± 0.072
0.611LeuCys: 0.611 ± 0.022
5.065LeuAsp: 5.065 ± 0.08
6.004LeuGlu: 6.004 ± 0.086
4.971LeuPhe: 4.971 ± 0.086
5.539LeuGly: 5.539 ± 0.076
1.509LeuHis: 1.509 ± 0.038
7.139LeuIle: 7.139 ± 0.11
8.178LeuLys: 8.178 ± 0.124
8.555LeuLeu: 8.555 ± 0.123
1.627LeuMet: 1.627 ± 0.045
6.204LeuAsn: 6.204 ± 0.081
3.318LeuPro: 3.318 ± 0.054
3.191LeuGln: 3.191 ± 0.052
2.941LeuArg: 2.941 ± 0.056
6.806LeuSer: 6.806 ± 0.08
5.409LeuThr: 5.409 ± 0.107
5.118LeuVal: 5.118 ± 0.069
0.724LeuTrp: 0.724 ± 0.025
3.178LeuTyr: 3.178 ± 0.051
0.0LeuXaa: 0.0 ± 0.0
Met
1.074MetAla: 1.074 ± 0.032
0.12MetCys: 0.12 ± 0.009
0.849MetAsp: 0.849 ± 0.028
0.996MetGlu: 0.996 ± 0.03
0.783MetPhe: 0.783 ± 0.037
1.048MetGly: 1.048 ± 0.026
0.324MetHis: 0.324 ± 0.014
1.397MetIle: 1.397 ± 0.033
2.149MetLys: 2.149 ± 0.049
1.636MetLeu: 1.636 ± 0.041
0.458MetMet: 0.458 ± 0.021
1.284MetAsn: 1.284 ± 0.034
0.632MetPro: 0.632 ± 0.025
0.598MetGln: 0.598 ± 0.021
0.747MetArg: 0.747 ± 0.023
1.205MetSer: 1.205 ± 0.028
0.932MetThr: 0.932 ± 0.026
1.008MetVal: 1.008 ± 0.032
0.137MetTrp: 0.137 ± 0.01
0.697MetTyr: 0.697 ± 0.024
0.0MetXaa: 0.0 ± 0.0
Asn
3.776AsnAla: 3.776 ± 0.081
0.528AsnCys: 0.528 ± 0.021
3.746AsnAsp: 3.746 ± 0.069
4.323AsnGlu: 4.323 ± 0.057
3.668AsnPhe: 3.668 ± 0.062
4.477AsnGly: 4.477 ± 0.1
1.168AsnHis: 1.168 ± 0.03
5.335AsnIle: 5.335 ± 0.068
5.16AsnLys: 5.16 ± 0.077
5.943AsnLeu: 5.943 ± 0.09
1.126AsnMet: 1.126 ± 0.032
4.953AsnAsn: 4.953 ± 0.112
2.8AsnPro: 2.8 ± 0.049
2.425AsnGln: 2.425 ± 0.046
2.256AsnArg: 2.256 ± 0.046
4.702AsnSer: 4.702 ± 0.074
4.541AsnThr: 4.541 ± 0.081
3.931AsnVal: 3.931 ± 0.081
0.827AsnTrp: 0.827 ± 0.028
3.235AsnTyr: 3.235 ± 0.056
0.0AsnXaa: 0.0 ± 0.0
Pro
1.596ProAla: 1.596 ± 0.054
0.196ProCys: 0.196 ± 0.012
1.875ProAsp: 1.875 ± 0.044
2.425ProGlu: 2.425 ± 0.053
1.786ProPhe: 1.786 ± 0.044
1.666ProGly: 1.666 ± 0.062
0.55ProHis: 0.55 ± 0.02
2.573ProIle: 2.573 ± 0.052
2.631ProLys: 2.631 ± 0.053
2.612ProLeu: 2.612 ± 0.051
0.57ProMet: 0.57 ± 0.019
2.499ProAsn: 2.499 ± 0.073
0.76ProPro: 0.76 ± 0.035
0.91ProGln: 0.91 ± 0.029
0.862ProArg: 0.862 ± 0.028
2.153ProSer: 2.153 ± 0.053
1.981ProThr: 1.981 ± 0.055
2.211ProVal: 2.211 ± 0.055
0.321ProTrp: 0.321 ± 0.018
1.308ProTyr: 1.308 ± 0.035
0.0ProXaa: 0.0 ± 0.0
Gln
1.615GlnAla: 1.615 ± 0.039
0.169GlnCys: 0.169 ± 0.01
1.547GlnAsp: 1.547 ± 0.041
2.475GlnGlu: 2.475 ± 0.048
1.76GlnPhe: 1.76 ± 0.038
1.597GlnGly: 1.597 ± 0.036
0.567GlnHis: 0.567 ± 0.021
2.719GlnIle: 2.719 ± 0.042
3.114GlnLys: 3.114 ± 0.063
3.258GlnLeu: 3.258 ± 0.061
0.671GlnMet: 0.671 ± 0.02
2.252GlnAsn: 2.252 ± 0.051
0.997GlnPro: 0.997 ± 0.03
1.409GlnGln: 1.409 ± 0.04
1.146GlnArg: 1.146 ± 0.029
1.841GlnSer: 1.841 ± 0.04
1.797GlnThr: 1.797 ± 0.04
1.838GlnVal: 1.838 ± 0.043
0.343GlnTrp: 0.343 ± 0.017
1.184GlnTyr: 1.184 ± 0.032
0.0GlnXaa: 0.0 ± 0.0
Arg
1.875ArgAla: 1.875 ± 0.041
0.204ArgCys: 0.204 ± 0.013
1.626ArgAsp: 1.626 ± 0.039
2.066ArgGlu: 2.066 ± 0.044
1.93ArgPhe: 1.93 ± 0.043
1.882ArgGly: 1.882 ± 0.049
0.504ArgHis: 0.504 ± 0.021
2.929ArgIle: 2.929 ± 0.048
3.047ArgLys: 3.047 ± 0.061
3.059ArgLeu: 3.059 ± 0.053
0.739ArgMet: 0.739 ± 0.027
2.304ArgAsn: 2.304 ± 0.047
0.911ArgPro: 0.911 ± 0.028
0.923ArgGln: 0.923 ± 0.024
1.287ArgArg: 1.287 ± 0.034
1.869ArgSer: 1.869 ± 0.044
1.763ArgThr: 1.763 ± 0.039
2.136ArgVal: 2.136 ± 0.043
0.369ArgTrp: 0.369 ± 0.016
1.426ArgTyr: 1.426 ± 0.031
0.0ArgXaa: 0.0 ± 0.0
Ser
3.281SerAla: 3.281 ± 0.052
0.736SerCys: 0.736 ± 0.024
3.726SerAsp: 3.726 ± 0.073
4.338SerGlu: 4.338 ± 0.072
4.299SerPhe: 4.299 ± 0.064
4.726SerGly: 4.726 ± 0.114
1.023SerHis: 1.023 ± 0.029
5.742SerIle: 5.742 ± 0.072
5.55SerLys: 5.55 ± 0.081
6.327SerLeu: 6.327 ± 0.086
1.146SerMet: 1.146 ± 0.033
4.588SerAsn: 4.588 ± 0.091
2.027SerPro: 2.027 ± 0.055
1.958SerGln: 1.958 ± 0.037
2.07SerArg: 2.07 ± 0.047
4.944SerSer: 4.944 ± 0.09
3.674SerThr: 3.674 ± 0.071
4.069SerVal: 4.069 ± 0.096
0.785SerTrp: 0.785 ± 0.029
2.966SerTyr: 2.966 ± 0.05
0.0SerXaa: 0.0 ± 0.0
Thr
3.442ThrAla: 3.442 ± 0.094
0.411ThrCys: 0.411 ± 0.026
3.397ThrAsp: 3.397 ± 0.08
3.534ThrGlu: 3.534 ± 0.055
3.164ThrPhe: 3.164 ± 0.064
3.898ThrGly: 3.898 ± 0.12
0.997ThrHis: 0.997 ± 0.03
5.496ThrIle: 5.496 ± 0.087
4.499ThrLys: 4.499 ± 0.061
5.294ThrLeu: 5.294 ± 0.07
0.854ThrMet: 0.854 ± 0.028
4.099ThrAsn: 4.099 ± 0.087
2.496ThrPro: 2.496 ± 0.081
1.87ThrGln: 1.87 ± 0.046
1.688ThrArg: 1.688 ± 0.042
4.512ThrSer: 4.512 ± 0.091
3.898ThrThr: 3.898 ± 0.102
4.115ThrVal: 4.115 ± 0.147
0.633ThrTrp: 0.633 ± 0.027
2.548ThrTyr: 2.548 ± 0.065
0.0ThrXaa: 0.0 ± 0.0
Val
3.732ValAla: 3.732 ± 0.065
0.48ValCys: 0.48 ± 0.022
3.567ValAsp: 3.567 ± 0.084
3.739ValGlu: 3.739 ± 0.053
3.456ValPhe: 3.456 ± 0.055
3.612ValGly: 3.612 ± 0.066
0.926ValHis: 0.926 ± 0.028
4.753ValIle: 4.753 ± 0.062
4.699ValLys: 4.699 ± 0.081
5.795ValLeu: 5.795 ± 0.073
1.075ValMet: 1.075 ± 0.028
4.072ValAsn: 4.072 ± 0.069
1.953ValPro: 1.953 ± 0.046
1.756ValGln: 1.756 ± 0.04
1.926ValArg: 1.926 ± 0.045
4.648ValSer: 4.648 ± 0.082
4.015ValThr: 4.015 ± 0.114
4.068ValVal: 4.068 ± 0.073
0.607ValTrp: 0.607 ± 0.023
2.342ValTyr: 2.342 ± 0.048
0.0ValXaa: 0.0 ± 0.0
Trp
0.495TrpAla: 0.495 ± 0.021
0.102TrpCys: 0.102 ± 0.008
0.559TrpAsp: 0.559 ± 0.023
0.619TrpGlu: 0.619 ± 0.023
0.57TrpPhe: 0.57 ± 0.022
0.604TrpGly: 0.604 ± 0.03
0.182TrpHis: 0.182 ± 0.011
0.745TrpIle: 0.745 ± 0.028
0.934TrpLys: 0.934 ± 0.03
0.922TrpLeu: 0.922 ± 0.031
0.249TrpMet: 0.249 ± 0.014
0.772TrpAsn: 0.772 ± 0.033
0.186TrpPro: 0.186 ± 0.013
0.346TrpGln: 0.346 ± 0.015
0.386TrpArg: 0.386 ± 0.016
0.715TrpSer: 0.715 ± 0.03
0.568TrpThr: 0.568 ± 0.029
0.578TrpVal: 0.578 ± 0.021
0.138TrpTrp: 0.138 ± 0.011
0.465TrpTyr: 0.465 ± 0.022
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.217TyrAla: 2.217 ± 0.043
0.34TyrCys: 0.34 ± 0.018
2.322TyrAsp: 2.322 ± 0.047
2.394TyrGlu: 2.394 ± 0.048
2.41TyrPhe: 2.41 ± 0.048
2.391TyrGly: 2.391 ± 0.047
0.798TyrHis: 0.798 ± 0.03
2.904TyrIle: 2.904 ± 0.052
3.444TyrLys: 3.444 ± 0.062
3.805TyrLeu: 3.805 ± 0.059
0.621TyrMet: 0.621 ± 0.021
2.824TyrAsn: 2.824 ± 0.053
1.37TyrPro: 1.37 ± 0.033
1.496TyrGln: 1.496 ± 0.038
1.564TyrArg: 1.564 ± 0.038
2.76TyrSer: 2.76 ± 0.046
2.685TyrThr: 2.685 ± 0.07
2.232TyrVal: 2.232 ± 0.046
0.44TyrTrp: 0.44 ± 0.023
1.946TyrTyr: 1.946 ± 0.043
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3944 proteins (1390372 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski