Amino acid dipepetide frequency for Neokomagataea tanensis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
12.418AlaAla: 12.418 ± 0.19
1.209AlaCys: 1.209 ± 0.042
5.342AlaAsp: 5.342 ± 0.082
6.617AlaGlu: 6.617 ± 0.125
3.89AlaPhe: 3.89 ± 0.079
8.495AlaGly: 8.495 ± 0.125
2.573AlaHis: 2.573 ± 0.07
5.32AlaIle: 5.32 ± 0.096
3.526AlaLys: 3.526 ± 0.074
13.321AlaLeu: 13.321 ± 0.188
2.725AlaMet: 2.725 ± 0.058
2.944AlaAsn: 2.944 ± 0.069
5.57AlaPro: 5.57 ± 0.107
4.929AlaGln: 4.929 ± 0.105
7.205AlaArg: 7.205 ± 0.119
6.72AlaSer: 6.72 ± 0.098
5.449AlaThr: 5.449 ± 0.091
7.427AlaVal: 7.427 ± 0.111
1.298AlaTrp: 1.298 ± 0.043
2.412AlaTyr: 2.412 ± 0.062
0.0AlaXaa: 0.0 ± 0.0
Cys
1.183CysAla: 1.183 ± 0.044
0.157CysCys: 0.157 ± 0.013
0.548CysAsp: 0.548 ± 0.031
0.419CysGlu: 0.419 ± 0.023
0.403CysPhe: 0.403 ± 0.023
1.011CysGly: 1.011 ± 0.042
0.25CysHis: 0.25 ± 0.02
0.486CysIle: 0.486 ± 0.028
0.217CysLys: 0.217 ± 0.018
0.95CysLeu: 0.95 ± 0.037
0.155CysMet: 0.155 ± 0.013
0.267CysAsn: 0.267 ± 0.02
0.478CysPro: 0.478 ± 0.028
0.255CysGln: 0.255 ± 0.019
0.564CysArg: 0.564 ± 0.031
0.669CysSer: 0.669 ± 0.031
0.556CysThr: 0.556 ± 0.026
0.805CysVal: 0.805 ± 0.04
0.125CysTrp: 0.125 ± 0.013
0.225CysTyr: 0.225 ± 0.017
0.0CysXaa: 0.0 ± 0.0
Asp
6.076AspAla: 6.076 ± 0.104
0.484AspCys: 0.484 ± 0.028
2.71AspAsp: 2.71 ± 0.067
3.133AspGlu: 3.133 ± 0.075
2.009AspPhe: 2.009 ± 0.052
4.555AspGly: 4.555 ± 0.084
1.309AspHis: 1.309 ± 0.044
3.244AspIle: 3.244 ± 0.067
1.541AspLys: 1.541 ± 0.044
5.254AspLeu: 5.254 ± 0.081
1.285AspMet: 1.285 ± 0.039
1.522AspAsn: 1.522 ± 0.043
2.844AspPro: 2.844 ± 0.074
1.783AspGln: 1.783 ± 0.046
3.468AspArg: 3.468 ± 0.072
2.322AspSer: 2.322 ± 0.055
2.847AspThr: 2.847 ± 0.066
4.297AspVal: 4.297 ± 0.065
0.851AspTrp: 0.851 ± 0.031
1.403AspTyr: 1.403 ± 0.044
0.0AspXaa: 0.0 ± 0.0
Glu
6.571GluAla: 6.571 ± 0.125
0.402GluCys: 0.402 ± 0.025
2.642GluAsp: 2.642 ± 0.069
3.119GluGlu: 3.119 ± 0.093
1.469GluPhe: 1.469 ± 0.05
4.061GluGly: 4.061 ± 0.08
1.658GluHis: 1.658 ± 0.053
3.183GluIle: 3.183 ± 0.074
2.365GluLys: 2.365 ± 0.065
4.598GluLeu: 4.598 ± 0.095
1.284GluMet: 1.284 ± 0.048
2.068GluAsn: 2.068 ± 0.054
1.997GluPro: 1.997 ± 0.056
2.467GluGln: 2.467 ± 0.062
4.596GluArg: 4.596 ± 0.096
2.528GluSer: 2.528 ± 0.063
3.518GluThr: 3.518 ± 0.075
3.232GluVal: 3.232 ± 0.07
0.727GluTrp: 0.727 ± 0.03
1.081GluTyr: 1.081 ± 0.039
0.0GluXaa: 0.0 ± 0.0
Phe
3.777PheAla: 3.777 ± 0.077
0.484PheCys: 0.484 ± 0.025
2.263PheAsp: 2.263 ± 0.056
1.948PheGlu: 1.948 ± 0.056
1.506PhePhe: 1.506 ± 0.055
3.529PheGly: 3.529 ± 0.08
0.83PheHis: 0.83 ± 0.035
1.837PheIle: 1.837 ± 0.053
1.092PheLys: 1.092 ± 0.045
3.609PheLeu: 3.609 ± 0.082
0.802PheMet: 0.802 ± 0.033
1.372PheAsn: 1.372 ± 0.049
1.522PhePro: 1.522 ± 0.052
1.187PheGln: 1.187 ± 0.038
2.065PheArg: 2.065 ± 0.057
2.864PheSer: 2.864 ± 0.072
2.077PheThr: 2.077 ± 0.05
2.577PheVal: 2.577 ± 0.061
0.54PheTrp: 0.54 ± 0.029
0.989PheTyr: 0.989 ± 0.032
0.0PheXaa: 0.0 ± 0.0
Gly
8.169GlyAla: 8.169 ± 0.113
0.844GlyCys: 0.844 ± 0.034
3.8GlyAsp: 3.8 ± 0.074
3.916GlyGlu: 3.916 ± 0.081
3.38GlyPhe: 3.38 ± 0.071
6.807GlyGly: 6.807 ± 0.142
2.184GlyHis: 2.184 ± 0.06
4.503GlyIle: 4.503 ± 0.093
3.102GlyLys: 3.102 ± 0.066
8.391GlyLeu: 8.391 ± 0.131
2.11GlyMet: 2.11 ± 0.059
2.57GlyAsn: 2.57 ± 0.074
3.136GlyPro: 3.136 ± 0.066
3.279GlyGln: 3.279 ± 0.068
5.484GlyArg: 5.484 ± 0.103
4.765GlySer: 4.765 ± 0.103
4.822GlyThr: 4.822 ± 0.104
5.943GlyVal: 5.943 ± 0.092
1.327GlyTrp: 1.327 ± 0.05
2.297GlyTyr: 2.297 ± 0.058
0.0GlyXaa: 0.0 ± 0.0
His
2.725HisAla: 2.725 ± 0.074
0.242HisCys: 0.242 ± 0.017
1.506HisAsp: 1.506 ± 0.045
1.161HisGlu: 1.161 ± 0.042
1.068HisPhe: 1.068 ± 0.035
2.136HisGly: 2.136 ± 0.063
0.818HisHis: 0.818 ± 0.038
1.403HisIle: 1.403 ± 0.04
0.801HisLys: 0.801 ± 0.032
2.445HisLeu: 2.445 ± 0.063
0.562HisMet: 0.562 ± 0.029
0.879HisAsn: 0.879 ± 0.035
1.468HisPro: 1.468 ± 0.041
0.771HisGln: 0.771 ± 0.031
1.415HisArg: 1.415 ± 0.048
1.448HisSer: 1.448 ± 0.048
1.278HisThr: 1.278 ± 0.035
1.809HisVal: 1.809 ± 0.06
0.408HisTrp: 0.408 ± 0.024
0.784HisTyr: 0.784 ± 0.036
0.0HisXaa: 0.0 ± 0.0
Ile
6.281IleAla: 6.281 ± 0.094
0.596IleCys: 0.596 ± 0.031
3.246IleAsp: 3.246 ± 0.071
3.244IleGlu: 3.244 ± 0.079
1.809IlePhe: 1.809 ± 0.062
4.696IleGly: 4.696 ± 0.084
1.136IleHis: 1.136 ± 0.039
2.971IleIle: 2.971 ± 0.084
1.665IleLys: 1.665 ± 0.052
5.122IleLeu: 5.122 ± 0.1
1.107IleMet: 1.107 ± 0.039
1.912IleAsn: 1.912 ± 0.06
2.748IlePro: 2.748 ± 0.056
1.585IleGln: 1.585 ± 0.048
3.277IleArg: 3.277 ± 0.065
3.625IleSer: 3.625 ± 0.073
3.22IleThr: 3.22 ± 0.075
3.897IleVal: 3.897 ± 0.086
0.566IleTrp: 0.566 ± 0.028
1.1IleTyr: 1.1 ± 0.039
0.0IleXaa: 0.0 ± 0.0
Lys
4.037LysAla: 4.037 ± 0.073
0.21LysCys: 0.21 ± 0.018
1.929LysAsp: 1.929 ± 0.065
1.757LysGlu: 1.757 ± 0.056
0.875LysPhe: 0.875 ± 0.038
2.545LysGly: 2.545 ± 0.054
0.86LysHis: 0.86 ± 0.032
2.251LysIle: 2.251 ± 0.058
1.681LysLys: 1.681 ± 0.062
3.202LysLeu: 3.202 ± 0.059
0.829LysMet: 0.829 ± 0.036
1.564LysAsn: 1.564 ± 0.055
1.872LysPro: 1.872 ± 0.049
1.254LysGln: 1.254 ± 0.043
2.431LysArg: 2.431 ± 0.058
1.951LysSer: 1.951 ± 0.054
2.445LysThr: 2.445 ± 0.066
2.058LysVal: 2.058 ± 0.047
0.353LysTrp: 0.353 ± 0.022
0.764LysTyr: 0.764 ± 0.038
0.0LysXaa: 0.0 ± 0.0
Leu
11.358LeuAla: 11.358 ± 0.15
1.142LeuCys: 1.142 ± 0.044
5.48LeuAsp: 5.48 ± 0.102
5.29LeuGlu: 5.29 ± 0.096
3.647LeuPhe: 3.647 ± 0.077
7.807LeuGly: 7.807 ± 0.119
2.619LeuHis: 2.619 ± 0.063
5.02LeuIle: 5.02 ± 0.092
4.102LeuLys: 4.102 ± 0.076
9.857LeuLeu: 9.857 ± 0.187
2.279LeuMet: 2.279 ± 0.071
3.583LeuAsn: 3.583 ± 0.075
6.191LeuPro: 6.191 ± 0.094
3.488LeuGln: 3.488 ± 0.077
7.076LeuArg: 7.076 ± 0.11
7.879LeuSer: 7.879 ± 0.104
6.381LeuThr: 6.381 ± 0.11
6.544LeuVal: 6.544 ± 0.096
1.183LeuTrp: 1.183 ± 0.049
2.255LeuTyr: 2.255 ± 0.055
0.0LeuXaa: 0.0 ± 0.0
Met
2.636MetAla: 2.636 ± 0.065
0.198MetCys: 0.198 ± 0.018
1.088MetAsp: 1.088 ± 0.041
0.967MetGlu: 0.967 ± 0.037
0.695MetPhe: 0.695 ± 0.031
1.72MetGly: 1.72 ± 0.046
0.514MetHis: 0.514 ± 0.03
1.195MetIle: 1.195 ± 0.042
0.836MetLys: 0.836 ± 0.034
2.404MetLeu: 2.404 ± 0.062
0.63MetMet: 0.63 ± 0.031
0.784MetAsn: 0.784 ± 0.035
1.429MetPro: 1.429 ± 0.044
0.89MetGln: 0.89 ± 0.039
1.651MetArg: 1.651 ± 0.041
1.769MetSer: 1.769 ± 0.046
1.672MetThr: 1.672 ± 0.042
1.548MetVal: 1.548 ± 0.044
0.174MetTrp: 0.174 ± 0.016
0.311MetTyr: 0.311 ± 0.022
0.0MetXaa: 0.0 ± 0.0
Asn
3.805AsnAla: 3.805 ± 0.072
0.258AsnCys: 0.258 ± 0.021
1.758AsnAsp: 1.758 ± 0.054
1.342AsnGlu: 1.342 ± 0.043
1.297AsnPhe: 1.297 ± 0.045
3.045AsnGly: 3.045 ± 0.077
0.677AsnHis: 0.677 ± 0.033
2.194AsnIle: 2.194 ± 0.058
1.03AsnLys: 1.03 ± 0.045
3.102AsnLeu: 3.102 ± 0.073
0.738AsnMet: 0.738 ± 0.032
1.38AsnAsn: 1.38 ± 0.057
2.009AsnPro: 2.009 ± 0.062
1.137AsnGln: 1.137 ± 0.042
1.925AsnArg: 1.925 ± 0.051
1.844AsnSer: 1.844 ± 0.066
2.142AsnThr: 2.142 ± 0.063
2.407AsnVal: 2.407 ± 0.068
0.537AsnTrp: 0.537 ± 0.029
0.966AsnTyr: 0.966 ± 0.046
0.0AsnXaa: 0.0 ± 0.0
Pro
5.227ProAla: 5.227 ± 0.094
0.421ProCys: 0.421 ± 0.022
3.254ProAsp: 3.254 ± 0.071
3.665ProGlu: 3.665 ± 0.082
1.981ProPhe: 1.981 ± 0.048
3.805ProGly: 3.805 ± 0.07
1.374ProHis: 1.374 ± 0.044
2.478ProIle: 2.478 ± 0.068
1.775ProLys: 1.775 ± 0.051
4.971ProLeu: 4.971 ± 0.103
1.08ProMet: 1.08 ± 0.034
1.836ProAsn: 1.836 ± 0.048
2.49ProPro: 2.49 ± 0.085
2.056ProGln: 2.056 ± 0.056
2.54ProArg: 2.54 ± 0.054
3.649ProSer: 3.649 ± 0.076
2.9ProThr: 2.9 ± 0.074
3.905ProVal: 3.905 ± 0.069
0.676ProTrp: 0.676 ± 0.025
1.275ProTyr: 1.275 ± 0.041
0.0ProXaa: 0.0 ± 0.0
Gln
4.294GlnAla: 4.294 ± 0.087
0.244GlnCys: 0.244 ± 0.021
1.982GlnAsp: 1.982 ± 0.051
1.867GlnGlu: 1.867 ± 0.055
1.197GlnPhe: 1.197 ± 0.042
2.78GlnGly: 2.78 ± 0.071
1.014GlnHis: 1.014 ± 0.037
2.167GlnIle: 2.167 ± 0.051
1.754GlnLys: 1.754 ± 0.053
3.098GlnLeu: 3.098 ± 0.071
0.814GlnMet: 0.814 ± 0.03
1.631GlnAsn: 1.631 ± 0.055
1.957GlnPro: 1.957 ± 0.059
1.568GlnGln: 1.568 ± 0.052
2.589GlnArg: 2.589 ± 0.062
2.484GlnSer: 2.484 ± 0.065
2.345GlnThr: 2.345 ± 0.063
2.383GlnVal: 2.383 ± 0.057
0.49GlnTrp: 0.49 ± 0.029
0.867GlnTyr: 0.867 ± 0.042
0.0GlnXaa: 0.0 ± 0.0
Arg
6.597ArgAla: 6.597 ± 0.119
0.517ArgCys: 0.517 ± 0.025
3.487ArgAsp: 3.487 ± 0.073
3.547ArgGlu: 3.547 ± 0.082
2.826ArgPhe: 2.826 ± 0.062
4.476ArgGly: 4.476 ± 0.079
1.782ArgHis: 1.782 ± 0.05
3.619ArgIle: 3.619 ± 0.066
2.326ArgLys: 2.326 ± 0.063
7.422ArgLeu: 7.422 ± 0.109
1.587ArgMet: 1.587 ± 0.047
2.081ArgAsn: 2.081 ± 0.058
3.072ArgPro: 3.072 ± 0.069
2.501ArgGln: 2.501 ± 0.062
4.705ArgArg: 4.705 ± 0.101
3.982ArgSer: 3.982 ± 0.087
3.149ArgThr: 3.149 ± 0.068
4.434ArgVal: 4.434 ± 0.08
0.92ArgTrp: 0.92 ± 0.037
1.829ArgTyr: 1.829 ± 0.048
0.0ArgXaa: 0.0 ± 0.0
Ser
7.004SerAla: 7.004 ± 0.111
0.593SerCys: 0.593 ± 0.03
3.217SerAsp: 3.217 ± 0.062
3.148SerGlu: 3.148 ± 0.073
2.712SerPhe: 2.712 ± 0.071
6.042SerGly: 6.042 ± 0.111
1.404SerHis: 1.404 ± 0.045
3.4SerIle: 3.4 ± 0.067
1.936SerLys: 1.936 ± 0.054
7.0SerLeu: 7.0 ± 0.113
1.354SerMet: 1.354 ± 0.043
1.957SerAsn: 1.957 ± 0.059
3.144SerPro: 3.144 ± 0.075
2.088SerGln: 2.088 ± 0.058
3.638SerArg: 3.638 ± 0.077
4.3SerSer: 4.3 ± 0.099
3.514SerThr: 3.514 ± 0.079
4.798SerVal: 4.798 ± 0.083
0.833SerTrp: 0.833 ± 0.035
1.653SerTyr: 1.653 ± 0.063
0.0SerXaa: 0.0 ± 0.0
Thr
6.145ThrAla: 6.145 ± 0.102
0.513ThrCys: 0.513 ± 0.027
2.87ThrAsp: 2.87 ± 0.064
2.729ThrGlu: 2.729 ± 0.066
1.969ThrPhe: 1.969 ± 0.057
4.97ThrGly: 4.97 ± 0.091
1.474ThrHis: 1.474 ± 0.044
3.179ThrIle: 3.179 ± 0.081
1.62ThrLys: 1.62 ± 0.048
7.049ThrLeu: 7.049 ± 0.103
1.134ThrMet: 1.134 ± 0.037
1.832ThrAsn: 1.832 ± 0.067
3.883ThrPro: 3.883 ± 0.086
2.18ThrGln: 2.18 ± 0.056
3.296ThrArg: 3.296 ± 0.07
3.67ThrSer: 3.67 ± 0.082
3.296ThrThr: 3.296 ± 0.086
4.228ThrVal: 4.228 ± 0.081
0.632ThrTrp: 0.632 ± 0.032
1.415ThrTyr: 1.415 ± 0.05
0.0ThrXaa: 0.0 ± 0.0
Val
7.391ValAla: 7.391 ± 0.117
0.763ValCys: 0.763 ± 0.034
3.628ValAsp: 3.628 ± 0.077
3.99ValGlu: 3.99 ± 0.076
2.689ValPhe: 2.689 ± 0.07
5.061ValGly: 5.061 ± 0.091
1.621ValHis: 1.621 ± 0.05
3.663ValIle: 3.663 ± 0.073
2.26ValLys: 2.26 ± 0.062
7.514ValLeu: 7.514 ± 0.123
1.864ValMet: 1.864 ± 0.053
1.984ValAsn: 1.984 ± 0.066
3.768ValPro: 3.768 ± 0.073
2.594ValGln: 2.594 ± 0.066
4.232ValArg: 4.232 ± 0.088
5.005ValSer: 5.005 ± 0.088
4.369ValThr: 4.369 ± 0.072
5.492ValVal: 5.492 ± 0.1
0.915ValTrp: 0.915 ± 0.038
1.396ValTyr: 1.396 ± 0.044
0.0ValXaa: 0.0 ± 0.0
Trp
1.133TrpAla: 1.133 ± 0.042
0.178TrpCys: 0.178 ± 0.016
0.646TrpAsp: 0.646 ± 0.035
0.505TrpGlu: 0.505 ± 0.023
0.528TrpPhe: 0.528 ± 0.027
0.925TrpGly: 0.925 ± 0.042
0.44TrpHis: 0.44 ± 0.024
0.625TrpIle: 0.625 ± 0.029
0.49TrpLys: 0.49 ± 0.026
1.639TrpLeu: 1.639 ± 0.05
0.338TrpMet: 0.338 ± 0.019
0.49TrpAsn: 0.49 ± 0.03
0.628TrpPro: 0.628 ± 0.032
0.558TrpGln: 0.558 ± 0.028
1.083TrpArg: 1.083 ± 0.039
0.883TrpSer: 0.883 ± 0.031
0.706TrpThr: 0.706 ± 0.027
0.806TrpVal: 0.806 ± 0.032
0.202TrpTrp: 0.202 ± 0.017
0.345TrpTyr: 0.345 ± 0.023
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.566TyrAla: 2.566 ± 0.071
0.269TyrCys: 0.269 ± 0.019
1.54TyrAsp: 1.54 ± 0.05
1.201TyrGlu: 1.201 ± 0.042
0.923TyrPhe: 0.923 ± 0.037
2.364TyrGly: 2.364 ± 0.062
0.589TyrHis: 0.589 ± 0.027
1.061TyrIle: 1.061 ± 0.042
0.753TyrLys: 0.753 ± 0.031
2.236TyrLeu: 2.236 ± 0.063
0.434TyrMet: 0.434 ± 0.025
0.938TyrAsn: 0.938 ± 0.046
1.149TyrPro: 1.149 ± 0.034
0.954TyrGln: 0.954 ± 0.042
1.619TyrArg: 1.619 ± 0.043
1.376TyrSer: 1.376 ± 0.045
1.398TyrThr: 1.398 ± 0.058
1.612TyrVal: 1.612 ± 0.05
0.389TyrTrp: 0.389 ± 0.023
0.718TyrTyr: 0.718 ± 0.04
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2177 proteins (737012 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski