Amino acid dipepetide frequency for Choiromyces venosus 120613-1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	7.17AlaAla: 7.17 ± 0.059	0.991AlaCys: 0.991 ± 0.013	3.293AlaAsp: 3.293 ± 0.029	4.669AlaGlu: 4.669 ± 0.036	2.643AlaPhe: 2.643 ± 0.028	5.393AlaGly: 5.393 ± 0.036	1.594AlaHis: 1.594 ± 0.017	4.05AlaIle: 4.05 ± 0.035	3.915AlaLys: 3.915 ± 0.036	6.872AlaLeu: 6.872 ± 0.034	1.718AlaMet: 1.718 ± 0.019	2.585AlaAsn: 2.585 ± 0.025	4.197AlaPro: 4.197 ± 0.042	2.732AlaGln: 2.732 ± 0.027	4.379AlaArg: 4.379 ± 0.031	5.994AlaSer: 5.994 ± 0.04	4.646AlaThr: 4.646 ± 0.037	4.798AlaVal: 4.798 ± 0.032	0.925AlaTrp: 0.925 ± 0.014	1.862AlaTyr: 1.862 ± 0.022	0.0AlaXaa: 0.0 ± 0.0
Cys	0.884CysAla: 0.884 ± 0.014	0.336CysCys: 0.336 ± 0.009	0.66CysAsp: 0.66 ± 0.01	0.723CysGlu: 0.723 ± 0.013	0.643CysPhe: 0.643 ± 0.012	1.067CysGly: 1.067 ± 0.016	0.407CysHis: 0.407 ± 0.01	0.783CysIle: 0.783 ± 0.013	0.648CysLys: 0.648 ± 0.012	1.466CysLeu: 1.466 ± 0.017	0.324CysMet: 0.324 ± 0.007	0.509CysAsn: 0.509 ± 0.01	0.808CysPro: 0.808 ± 0.02	0.537CysGln: 0.537 ± 0.013	0.806CysArg: 0.806 ± 0.014	1.073CysSer: 1.073 ± 0.017	0.844CysThr: 0.844 ± 0.014	0.814CysVal: 0.814 ± 0.014	0.248CysTrp: 0.248 ± 0.007	0.432CysTyr: 0.432 ± 0.009	0.0CysXaa: 0.0 ± 0.0
Asp	3.505AspAla: 3.505 ± 0.032	0.64AspCys: 0.64 ± 0.01	3.589AspAsp: 3.589 ± 0.041	4.234AspGlu: 4.234 ± 0.036	1.975AspPhe: 1.975 ± 0.023	3.825AspGly: 3.825 ± 0.03	1.166AspHis: 1.166 ± 0.018	3.003AspIle: 3.003 ± 0.026	2.459AspLys: 2.459 ± 0.023	4.589AspLeu: 4.589 ± 0.042	1.187AspMet: 1.187 ± 0.016	1.912AspAsn: 1.912 ± 0.019	2.906AspPro: 2.906 ± 0.025	1.568AspGln: 1.568 ± 0.021	2.74AspArg: 2.74 ± 0.024	3.863AspSer: 3.863 ± 0.03	2.675AspThr: 2.675 ± 0.023	3.271AspVal: 3.271 ± 0.029	0.784AspTrp: 0.784 ± 0.014	1.47AspTyr: 1.47 ± 0.015	0.0AspXaa: 0.0 ± 0.0
Glu	4.842GluAla: 4.842 ± 0.037	0.755GluCys: 0.755 ± 0.014	4.265GluAsp: 4.265 ± 0.036	6.757GluGlu: 6.757 ± 0.06	2.22GluPhe: 2.22 ± 0.026	4.476GluGly: 4.476 ± 0.036	1.309GluHis: 1.309 ± 0.018	3.478GluIle: 3.478 ± 0.029	4.486GluLys: 4.486 ± 0.045	5.207GluLeu: 5.207 ± 0.041	1.632GluMet: 1.632 ± 0.019	2.547GluAsn: 2.547 ± 0.025	2.364GluPro: 2.364 ± 0.028	2.149GluGln: 2.149 ± 0.026	4.28GluArg: 4.28 ± 0.039	4.254GluSer: 4.254 ± 0.03	3.252GluThr: 3.252 ± 0.025	4.143GluVal: 4.143 ± 0.032	0.948GluTrp: 0.948 ± 0.016	1.812GluTyr: 1.812 ± 0.018	0.0GluXaa: 0.0 ± 0.0
Phe	2.56PheAla: 2.56 ± 0.025	0.667PheCys: 0.667 ± 0.012	1.984PheAsp: 1.984 ± 0.022	2.147PheGlu: 2.147 ± 0.024	1.945PhePhe: 1.945 ± 0.028	2.696PheGly: 2.696 ± 0.029	1.004PheHis: 1.004 ± 0.016	1.864PheIle: 1.864 ± 0.021	1.654PheLys: 1.654 ± 0.02	3.885PheLeu: 3.885 ± 0.032	0.754PheMet: 0.754 ± 0.012	1.481PheAsn: 1.481 ± 0.018	2.134PhePro: 2.134 ± 0.026	1.298PheGln: 1.298 ± 0.016	1.972PheArg: 1.972 ± 0.021	3.213PheSer: 3.213 ± 0.027	2.298PheThr: 2.298 ± 0.023	2.294PheVal: 2.294 ± 0.023	0.576PheTrp: 0.576 ± 0.01	1.168PheTyr: 1.168 ± 0.015	0.0PheXaa: 0.0 ± 0.0
Gly	4.681GlyAla: 4.681 ± 0.038	0.988GlyCys: 0.988 ± 0.015	3.714GlyAsp: 3.714 ± 0.03	4.361GlyGlu: 4.361 ± 0.031	2.695GlyPhe: 2.695 ± 0.025	7.156GlyGly: 7.156 ± 0.058	1.623GlyHis: 1.623 ± 0.02	3.736GlyIle: 3.736 ± 0.031	4.03GlyLys: 4.03 ± 0.033	5.669GlyLeu: 5.669 ± 0.035	1.734GlyMet: 1.734 ± 0.019	2.831GlyAsn: 2.831 ± 0.032	2.946GlyPro: 2.946 ± 0.031	2.257GlyGln: 2.257 ± 0.025	4.518GlyArg: 4.518 ± 0.038	5.629GlySer: 5.629 ± 0.035	3.79GlyThr: 3.79 ± 0.031	4.792GlyVal: 4.792 ± 0.032	1.206GlyTrp: 1.206 ± 0.016	2.083GlyTyr: 2.083 ± 0.023	0.0GlyXaa: 0.0 ± 0.0
His	1.578HisAla: 1.578 ± 0.017	0.43HisCys: 0.43 ± 0.01	1.107HisAsp: 1.107 ± 0.016	1.311HisGlu: 1.311 ± 0.018	0.966HisPhe: 0.966 ± 0.012	1.636HisGly: 1.636 ± 0.02	1.062HisHis: 1.062 ± 0.018	1.334HisIle: 1.334 ± 0.017	1.082HisLys: 1.082 ± 0.013	2.425HisLeu: 2.425 ± 0.024	0.495HisMet: 0.495 ± 0.011	0.974HisAsn: 0.974 ± 0.014	1.901HisPro: 1.901 ± 0.024	1.087HisGln: 1.087 ± 0.015	1.563HisArg: 1.563 ± 0.02	2.154HisSer: 2.154 ± 0.022	1.443HisThr: 1.443 ± 0.019	1.333HisVal: 1.333 ± 0.016	0.339HisTrp: 0.339 ± 0.007	0.752HisTyr: 0.752 ± 0.011	0.0HisXaa: 0.0 ± 0.0
Ile	3.824IleAla: 3.824 ± 0.028	0.887IleCys: 0.887 ± 0.013	2.692IleAsp: 2.692 ± 0.024	3.116IleGlu: 3.116 ± 0.025	2.08IlePhe: 2.08 ± 0.021	3.152IleGly: 3.152 ± 0.029	1.354IleHis: 1.354 ± 0.016	2.843IleIle: 2.843 ± 0.027	2.581IleLys: 2.581 ± 0.026	5.051IleLeu: 5.051 ± 0.034	1.114IleMet: 1.114 ± 0.013	1.943IleAsn: 1.943 ± 0.02	3.526IlePro: 3.526 ± 0.027	1.872IleGln: 1.872 ± 0.021	2.915IleArg: 2.915 ± 0.026	4.448IleSer: 4.448 ± 0.033	3.241IleThr: 3.241 ± 0.025	3.253IleVal: 3.253 ± 0.03	0.765IleTrp: 0.765 ± 0.012	1.472IleTyr: 1.472 ± 0.019	0.0IleXaa: 0.0 ± 0.0
Lys	4.128LysAla: 4.128 ± 0.036	0.648LysCys: 0.648 ± 0.013	2.838LysAsp: 2.838 ± 0.023	4.126LysGlu: 4.126 ± 0.04	1.694LysPhe: 1.694 ± 0.018	3.478LysGly: 3.478 ± 0.03	1.307LysHis: 1.307 ± 0.019	2.768LysIle: 2.768 ± 0.022	4.416LysLys: 4.416 ± 0.049	4.488LysLeu: 4.488 ± 0.033	1.196LysMet: 1.196 ± 0.015	2.072LysAsn: 2.072 ± 0.02	2.791LysPro: 2.791 ± 0.03	1.887LysGln: 1.887 ± 0.022	3.776LysArg: 3.776 ± 0.028	3.813LysSer: 3.813 ± 0.034	3.046LysThr: 3.046 ± 0.026	3.321LysVal: 3.321 ± 0.023	0.736LysTrp: 0.736 ± 0.011	1.562LysTyr: 1.562 ± 0.019	0.0LysXaa: 0.0 ± 0.0
Leu	7.023LeuAla: 7.023 ± 0.044	1.369LeuCys: 1.369 ± 0.023	4.722LeuAsp: 4.722 ± 0.031	5.812LeuGlu: 5.812 ± 0.044	3.591LeuPhe: 3.591 ± 0.032	5.779LeuGly: 5.779 ± 0.04	2.438LeuHis: 2.438 ± 0.025	4.004LeuIle: 4.004 ± 0.031	4.705LeuLys: 4.705 ± 0.037	9.29LeuLeu: 9.29 ± 0.066	1.853LeuMet: 1.853 ± 0.019	3.206LeuAsn: 3.206 ± 0.03	5.703LeuPro: 5.703 ± 0.039	3.743LeuGln: 3.743 ± 0.027	5.468LeuArg: 5.468 ± 0.042	7.605LeuSer: 7.605 ± 0.042	4.998LeuThr: 4.998 ± 0.029	5.372LeuVal: 5.372 ± 0.035	1.206LeuTrp: 1.206 ± 0.018	2.399LeuTyr: 2.399 ± 0.023	0.0LeuXaa: 0.0 ± 0.0
Met	1.87MetAla: 1.87 ± 0.019	0.275MetCys: 0.275 ± 0.007	1.229MetAsp: 1.229 ± 0.013	1.512MetGlu: 1.512 ± 0.019	0.794MetPhe: 0.794 ± 0.013	1.594MetGly: 1.594 ± 0.017	0.477MetHis: 0.477 ± 0.011	1.118MetIle: 1.118 ± 0.015	1.194MetLys: 1.194 ± 0.017	1.829MetLeu: 1.829 ± 0.019	0.581MetMet: 0.581 ± 0.012	0.832MetAsn: 0.832 ± 0.013	1.268MetPro: 1.268 ± 0.018	0.773MetGln: 0.773 ± 0.013	1.25MetArg: 1.25 ± 0.018	1.858MetSer: 1.858 ± 0.017	1.222MetThr: 1.222 ± 0.015	1.426MetVal: 1.426 ± 0.018	0.287MetTrp: 0.287 ± 0.007	0.504MetTyr: 0.504 ± 0.012	0.0MetXaa: 0.0 ± 0.0
Asn	2.694AsnAla: 2.694 ± 0.027	0.57AsnCys: 0.57 ± 0.011	1.738AsnAsp: 1.738 ± 0.017	1.995AsnGlu: 1.995 ± 0.025	1.446AsnPhe: 1.446 ± 0.017	2.855AsnGly: 2.855 ± 0.03	0.999AsnHis: 0.999 ± 0.015	2.297AsnIle: 2.297 ± 0.022	1.86AsnLys: 1.86 ± 0.022	3.525AsnLeu: 3.525 ± 0.028	0.855AsnMet: 0.855 ± 0.013	1.844AsnAsn: 1.844 ± 0.025	2.721AsnPro: 2.721 ± 0.024	1.368AsnGln: 1.368 ± 0.02	2.091AsnArg: 2.091 ± 0.022	3.247AsnSer: 3.247 ± 0.026	2.428AsnThr: 2.428 ± 0.025	2.221AsnVal: 2.221 ± 0.022	0.548AsnTrp: 0.548 ± 0.01	1.117AsnTyr: 1.117 ± 0.015	0.0AsnXaa: 0.0 ± 0.0
Pro	4.666ProAla: 4.666 ± 0.046	0.603ProCys: 0.603 ± 0.013	2.894ProAsp: 2.894 ± 0.026	3.669ProGlu: 3.669 ± 0.035	2.01ProPhe: 2.01 ± 0.02	3.845ProGly: 3.845 ± 0.037	1.582ProHis: 1.582 ± 0.022	2.878ProIle: 2.878 ± 0.026	2.795ProLys: 2.795 ± 0.028	5.188ProLeu: 5.188 ± 0.042	1.021ProMet: 1.021 ± 0.016	2.303ProAsn: 2.303 ± 0.026	6.513ProPro: 6.513 ± 0.09	2.397ProGln: 2.397 ± 0.032	3.327ProArg: 3.327 ± 0.033	5.975ProSer: 5.975 ± 0.047	4.565ProThr: 4.565 ± 0.035	3.535ProVal: 3.535 ± 0.03	0.61ProTrp: 0.61 ± 0.011	1.478ProTyr: 1.478 ± 0.035	0.0ProXaa: 0.0 ± 0.0
Gln	2.84GlnAla: 2.84 ± 0.028	0.496GlnCys: 0.496 ± 0.011	1.721GlnAsp: 1.721 ± 0.02	2.477GlnGlu: 2.477 ± 0.028	1.229GlnPhe: 1.229 ± 0.017	2.118GlnGly: 2.118 ± 0.025	1.003GlnHis: 1.003 ± 0.018	1.842GlnIle: 1.842 ± 0.021	2.157GlnLys: 2.157 ± 0.023	3.223GlnLeu: 3.223 ± 0.032	0.824GlnMet: 0.824 ± 0.014	1.538GlnAsn: 1.538 ± 0.017	2.235GlnPro: 2.235 ± 0.029	2.498GlnGln: 2.498 ± 0.06	2.313GlnArg: 2.313 ± 0.026	2.755GlnSer: 2.755 ± 0.026	2.162GlnThr: 2.162 ± 0.018	2.097GlnVal: 2.097 ± 0.022	0.476GlnTrp: 0.476 ± 0.008	1.069GlnTyr: 1.069 ± 0.015	0.0GlnXaa: 0.0 ± 0.0
Arg	4.264ArgAla: 4.264 ± 0.031	0.816ArgCys: 0.816 ± 0.012	3.024ArgAsp: 3.024 ± 0.026	4.24ArgGlu: 4.24 ± 0.039	2.182ArgPhe: 2.182 ± 0.025	4.123ArgGly: 4.123 ± 0.032	1.499ArgHis: 1.499 ± 0.018	3.216ArgIle: 3.216 ± 0.026	3.918ArgLys: 3.918 ± 0.027	5.121ArgLeu: 5.121 ± 0.033	1.443ArgMet: 1.443 ± 0.017	2.403ArgAsn: 2.403 ± 0.021	3.108ArgPro: 3.108 ± 0.031	2.252ArgGln: 2.252 ± 0.022	5.014ArgArg: 5.014 ± 0.045	4.559ArgSer: 4.559 ± 0.041	3.19ArgThr: 3.19 ± 0.026	3.556ArgVal: 3.556 ± 0.028	0.897ArgTrp: 0.897 ± 0.014	1.683ArgTyr: 1.683 ± 0.018	0.0ArgXaa: 0.0 ± 0.0
Ser	5.864SerAla: 5.864 ± 0.043	1.065SerCys: 1.065 ± 0.017	3.767SerAsp: 3.767 ± 0.029	4.271SerGlu: 4.271 ± 0.036	3.138SerPhe: 3.138 ± 0.025	5.847SerGly: 5.847 ± 0.039	2.091SerHis: 2.091 ± 0.022	4.114SerIle: 4.114 ± 0.031	3.81SerLys: 3.81 ± 0.032	7.45SerLeu: 7.45 ± 0.043	1.677SerMet: 1.677 ± 0.02	3.073SerAsn: 3.073 ± 0.03	6.101SerPro: 6.101 ± 0.058	3.012SerGln: 3.012 ± 0.028	4.841SerArg: 4.841 ± 0.041	9.174SerSer: 9.174 ± 0.078	5.836SerThr: 5.836 ± 0.043	4.385SerVal: 4.385 ± 0.03	1.03SerTrp: 1.03 ± 0.014	2.168SerTyr: 2.168 ± 0.025	0.0SerXaa: 0.0 ± 0.0
Thr	4.654ThrAla: 4.654 ± 0.034	0.809ThrCys: 0.809 ± 0.014	2.491ThrAsp: 2.491 ± 0.025	3.029ThrGlu: 3.029 ± 0.027	2.211ThrPhe: 2.211 ± 0.021	4.05ThrGly: 4.05 ± 0.03	1.465ThrHis: 1.465 ± 0.017	3.438ThrIle: 3.438 ± 0.026	2.791ThrLys: 2.791 ± 0.024	5.416ThrLeu: 5.416 ± 0.034	1.123ThrMet: 1.123 ± 0.015	2.276ThrAsn: 2.276 ± 0.022	5.115ThrPro: 5.115 ± 0.044	1.996ThrGln: 1.996 ± 0.022	3.122ThrArg: 3.122 ± 0.025	5.505ThrSer: 5.505 ± 0.042	4.945ThrThr: 4.945 ± 0.054	3.558ThrVal: 3.558 ± 0.033	0.749ThrTrp: 0.749 ± 0.013	1.65ThrTyr: 1.65 ± 0.018	0.0ThrXaa: 0.0 ± 0.0
Val	4.484ValAla: 4.484 ± 0.035	0.909ValCys: 0.909 ± 0.014	3.331ValAsp: 3.331 ± 0.027	4.268ValGlu: 4.268 ± 0.034	2.387ValPhe: 2.387 ± 0.025	4.35ValGly: 4.35 ± 0.031	1.379ValHis: 1.379 ± 0.016	3.14ValIle: 3.14 ± 0.026	3.423ValLys: 3.423 ± 0.027	5.591ValLeu: 5.591 ± 0.035	1.381ValMet: 1.381 ± 0.018	2.352ValAsn: 2.352 ± 0.023	3.433ValPro: 3.433 ± 0.028	2.129ValGln: 2.129 ± 0.021	3.542ValArg: 3.542 ± 0.025	4.441ValSer: 4.441 ± 0.03	3.373ValThr: 3.373 ± 0.033	4.416ValVal: 4.416 ± 0.039	0.899ValTrp: 0.899 ± 0.014	1.713ValTyr: 1.713 ± 0.016	0.0ValXaa: 0.0 ± 0.0
Trp	1.039TrpAla: 1.039 ± 0.016	0.24TrpCys: 0.24 ± 0.007	0.82TrpAsp: 0.82 ± 0.013	0.963TrpGlu: 0.963 ± 0.014	0.514TrpPhe: 0.514 ± 0.011	1.04TrpGly: 1.04 ± 0.014	0.333TrpHis: 0.333 ± 0.009	0.77TrpIle: 0.77 ± 0.014	0.874TrpLys: 0.874 ± 0.015	1.243TrpLeu: 1.243 ± 0.015	0.376TrpMet: 0.376 ± 0.008	0.575TrpAsn: 0.575 ± 0.011	0.525TrpPro: 0.525 ± 0.011	0.453TrpGln: 0.453 ± 0.01	0.945TrpArg: 0.945 ± 0.015	0.927TrpSer: 0.927 ± 0.015	0.766TrpThr: 0.766 ± 0.013	0.863TrpVal: 0.863 ± 0.013	0.289TrpTrp: 0.289 ± 0.009	0.403TrpTyr: 0.403 ± 0.009	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.856TyrAla: 1.856 ± 0.02	0.519TyrCys: 0.519 ± 0.011	1.483TyrAsp: 1.483 ± 0.017	1.499TyrGlu: 1.499 ± 0.018	1.236TyrPhe: 1.236 ± 0.017	1.958TyrGly: 1.958 ± 0.024	0.879TyrHis: 0.879 ± 0.014	1.452TyrIle: 1.452 ± 0.017	1.292TyrLys: 1.292 ± 0.025	2.756TyrLeu: 2.756 ± 0.026	0.605TyrMet: 0.605 ± 0.011	1.163TyrAsn: 1.163 ± 0.017	1.56TyrPro: 1.56 ± 0.017	1.064TyrGln: 1.064 ± 0.014	1.646TyrArg: 1.646 ± 0.016	2.226TyrSer: 2.226 ± 0.023	1.669TyrThr: 1.669 ± 0.022	1.495TyrVal: 1.495 ± 0.018	0.44TyrTrp: 0.44 ± 0.009	0.954TyrTyr: 0.954 ± 0.015	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.003XaaXaa: 0.003 ± 0.002

Statistics based on 17720 proteins (5377989 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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