Amino acid dipepetide frequency for Myroides indicus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.779AlaAla: 3.779 ± 0.081
0.614AlaCys: 0.614 ± 0.031
3.383AlaAsp: 3.383 ± 0.073
4.197AlaGlu: 4.197 ± 0.079
3.121AlaPhe: 3.121 ± 0.07
4.013AlaGly: 4.013 ± 0.088
1.04AlaHis: 1.04 ± 0.03
5.053AlaIle: 5.053 ± 0.086
4.512AlaLys: 4.512 ± 0.083
6.105AlaLeu: 6.105 ± 0.099
1.469AlaMet: 1.469 ± 0.041
3.057AlaAsn: 3.057 ± 0.073
1.691AlaPro: 1.691 ± 0.047
2.43AlaGln: 2.43 ± 0.055
1.861AlaArg: 1.861 ± 0.058
3.772AlaSer: 3.772 ± 0.066
3.282AlaThr: 3.282 ± 0.07
4.26AlaVal: 4.26 ± 0.077
0.608AlaTrp: 0.608 ± 0.031
2.534AlaTyr: 2.534 ± 0.059
0.0AlaXaa: 0.0 ± 0.0
Cys
0.457CysAla: 0.457 ± 0.024
0.116CysCys: 0.116 ± 0.012
0.403CysAsp: 0.403 ± 0.025
0.498CysGlu: 0.498 ± 0.026
0.473CysPhe: 0.473 ± 0.024
0.685CysGly: 0.685 ± 0.033
0.175CysHis: 0.175 ± 0.016
0.693CysIle: 0.693 ± 0.024
0.509CysLys: 0.509 ± 0.024
0.643CysLeu: 0.643 ± 0.03
0.15CysMet: 0.15 ± 0.012
0.429CysAsn: 0.429 ± 0.023
0.427CysPro: 0.427 ± 0.026
0.242CysGln: 0.242 ± 0.018
0.236CysArg: 0.236 ± 0.017
0.657CysSer: 0.657 ± 0.026
0.46CysThr: 0.46 ± 0.028
0.425CysVal: 0.425 ± 0.022
0.155CysTrp: 0.155 ± 0.023
0.314CysTyr: 0.314 ± 0.018
0.0CysXaa: 0.0 ± 0.0
Asp
3.071AspAla: 3.071 ± 0.09
0.547AspCys: 0.547 ± 0.04
2.621AspAsp: 2.621 ± 0.067
3.618AspGlu: 3.618 ± 0.066
3.621AspPhe: 3.621 ± 0.065
3.182AspGly: 3.182 ± 0.086
0.818AspHis: 0.818 ± 0.032
4.642AspIle: 4.642 ± 0.062
4.384AspLys: 4.384 ± 0.082
5.146AspLeu: 5.146 ± 0.072
1.06AspMet: 1.06 ± 0.036
3.199AspAsn: 3.199 ± 0.063
1.473AspPro: 1.473 ± 0.056
1.681AspGln: 1.681 ± 0.049
1.869AspArg: 1.869 ± 0.048
3.149AspSer: 3.149 ± 0.066
2.607AspThr: 2.607 ± 0.05
3.242AspVal: 3.242 ± 0.065
0.777AspTrp: 0.777 ± 0.034
2.919AspTyr: 2.919 ± 0.06
0.0AspXaa: 0.0 ± 0.0
Glu
4.153GluAla: 4.153 ± 0.081
0.4GluCys: 0.4 ± 0.023
3.355GluAsp: 3.355 ± 0.061
5.562GluGlu: 5.562 ± 0.088
2.99GluPhe: 2.99 ± 0.065
3.899GluGly: 3.899 ± 0.082
1.125GluHis: 1.125 ± 0.039
6.129GluIle: 6.129 ± 0.099
6.313GluLys: 6.313 ± 0.102
6.298GluLeu: 6.298 ± 0.098
1.664GluMet: 1.664 ± 0.05
4.78GluAsn: 4.78 ± 0.077
1.587GluPro: 1.587 ± 0.044
2.853GluGln: 2.853 ± 0.07
2.559GluArg: 2.559 ± 0.061
3.464GluSer: 3.464 ± 0.056
3.428GluThr: 3.428 ± 0.071
4.42GluVal: 4.42 ± 0.078
0.703GluTrp: 0.703 ± 0.03
3.052GluTyr: 3.052 ± 0.087
0.0GluXaa: 0.0 ± 0.0
Phe
3.006PheAla: 3.006 ± 0.063
0.53PheCys: 0.53 ± 0.026
3.164PheAsp: 3.164 ± 0.068
3.521PheGlu: 3.521 ± 0.06
2.883PhePhe: 2.883 ± 0.073
3.392PheGly: 3.392 ± 0.074
0.766PheHis: 0.766 ± 0.03
4.095PheIle: 4.095 ± 0.089
3.702PheLys: 3.702 ± 0.073
4.752PheLeu: 4.752 ± 0.101
1.125PheMet: 1.125 ± 0.037
3.122PheAsn: 3.122 ± 0.068
1.666PhePro: 1.666 ± 0.041
1.616PheGln: 1.616 ± 0.047
1.554PheArg: 1.554 ± 0.041
3.919PheSer: 3.919 ± 0.065
3.043PheThr: 3.043 ± 0.059
3.208PheVal: 3.208 ± 0.068
0.651PheTrp: 0.651 ± 0.034
2.311PheTyr: 2.311 ± 0.054
0.0PheXaa: 0.0 ± 0.0
Gly
4.005GlyAla: 4.005 ± 0.093
0.63GlyCys: 0.63 ± 0.035
3.189GlyAsp: 3.189 ± 0.079
3.769GlyGlu: 3.769 ± 0.076
3.406GlyPhe: 3.406 ± 0.075
4.522GlyGly: 4.522 ± 0.126
0.991GlyHis: 0.991 ± 0.038
5.62GlyIle: 5.62 ± 0.087
5.08GlyLys: 5.08 ± 0.085
5.272GlyLeu: 5.272 ± 0.099
1.623GlyMet: 1.623 ± 0.048
3.622GlyAsn: 3.622 ± 0.071
1.162GlyPro: 1.162 ± 0.042
1.95GlyGln: 1.95 ± 0.057
2.009GlyArg: 2.009 ± 0.059
3.826GlySer: 3.826 ± 0.086
4.026GlyThr: 4.026 ± 0.12
4.209GlyVal: 4.209 ± 0.081
0.678GlyTrp: 0.678 ± 0.026
2.86GlyTyr: 2.86 ± 0.069
0.0GlyXaa: 0.0 ± 0.0
His
0.909HisAla: 0.909 ± 0.03
0.163HisCys: 0.163 ± 0.013
0.795HisAsp: 0.795 ± 0.031
0.852HisGlu: 0.852 ± 0.029
1.164HisPhe: 1.164 ± 0.041
0.968HisGly: 0.968 ± 0.032
0.41HisHis: 0.41 ± 0.023
1.455HisIle: 1.455 ± 0.039
1.158HisLys: 1.158 ± 0.035
1.748HisLeu: 1.748 ± 0.059
0.312HisMet: 0.312 ± 0.017
1.008HisAsn: 1.008 ± 0.032
0.786HisPro: 0.786 ± 0.032
0.711HisGln: 0.711 ± 0.032
0.698HisArg: 0.698 ± 0.03
1.064HisSer: 1.064 ± 0.032
0.981HisThr: 0.981 ± 0.03
0.833HisVal: 0.833 ± 0.036
0.18HisTrp: 0.18 ± 0.015
0.923HisTyr: 0.923 ± 0.033
0.0HisXaa: 0.0 ± 0.0
Ile
5.621IleAla: 5.621 ± 0.084
0.71IleCys: 0.71 ± 0.029
5.071IleAsp: 5.071 ± 0.08
5.972IleGlu: 5.972 ± 0.108
3.708IlePhe: 3.708 ± 0.085
5.209IleGly: 5.209 ± 0.078
1.438IleHis: 1.438 ± 0.04
6.172IleIle: 6.172 ± 0.121
6.051IleLys: 6.051 ± 0.097
7.347IleLeu: 7.347 ± 0.118
1.449IleMet: 1.449 ± 0.044
4.864IleAsn: 4.864 ± 0.08
3.314IlePro: 3.314 ± 0.059
3.021IleGln: 3.021 ± 0.057
2.802IleArg: 2.802 ± 0.057
5.836IleSer: 5.836 ± 0.098
4.702IleThr: 4.702 ± 0.085
5.089IleVal: 5.089 ± 0.083
0.729IleTrp: 0.729 ± 0.027
3.317IleTyr: 3.317 ± 0.066
0.0IleXaa: 0.0 ± 0.0
Lys
4.837LysAla: 4.837 ± 0.096
0.346LysCys: 0.346 ± 0.019
4.449LysAsp: 4.449 ± 0.068
6.556LysGlu: 6.556 ± 0.103
2.845LysPhe: 2.845 ± 0.069
4.473LysGly: 4.473 ± 0.072
1.37LysHis: 1.37 ± 0.041
6.791LysIle: 6.791 ± 0.101
7.03LysLys: 7.03 ± 0.12
6.435LysLeu: 6.435 ± 0.103
2.173LysMet: 2.173 ± 0.049
5.505LysAsn: 5.505 ± 0.083
2.332LysPro: 2.332 ± 0.048
3.136LysGln: 3.136 ± 0.07
2.795LysArg: 2.795 ± 0.068
4.43LysSer: 4.43 ± 0.078
4.703LysThr: 4.703 ± 0.069
4.645LysVal: 4.645 ± 0.08
0.745LysTrp: 0.745 ± 0.028
3.385LysTyr: 3.385 ± 0.078
0.0LysXaa: 0.0 ± 0.0
Leu
5.505LeuAla: 5.505 ± 0.095
0.726LeuCys: 0.726 ± 0.03
4.746LeuAsp: 4.746 ± 0.066
6.109LeuGlu: 6.109 ± 0.098
5.099LeuPhe: 5.099 ± 0.112
5.585LeuGly: 5.585 ± 0.104
1.561LeuHis: 1.561 ± 0.047
7.342LeuIle: 7.342 ± 0.113
7.715LeuLys: 7.715 ± 0.12
9.086LeuLeu: 9.086 ± 0.161
2.213LeuMet: 2.213 ± 0.056
5.518LeuAsn: 5.518 ± 0.098
3.51LeuPro: 3.51 ± 0.059
3.397LeuGln: 3.397 ± 0.075
2.946LeuArg: 2.946 ± 0.061
6.912LeuSer: 6.912 ± 0.088
5.221LeuThr: 5.221 ± 0.097
4.802LeuVal: 4.802 ± 0.084
0.788LeuTrp: 0.788 ± 0.031
3.579LeuTyr: 3.579 ± 0.074
0.0LeuXaa: 0.0 ± 0.0
Met
1.551MetAla: 1.551 ± 0.046
0.142MetCys: 0.142 ± 0.012
1.189MetAsp: 1.189 ± 0.039
1.423MetGlu: 1.423 ± 0.041
0.932MetPhe: 0.932 ± 0.034
1.396MetGly: 1.396 ± 0.043
0.384MetHis: 0.384 ± 0.021
1.648MetIle: 1.648 ± 0.046
2.225MetLys: 2.225 ± 0.054
2.069MetLeu: 2.069 ± 0.049
0.577MetMet: 0.577 ± 0.029
1.379MetAsn: 1.379 ± 0.035
0.775MetPro: 0.775 ± 0.026
0.821MetGln: 0.821 ± 0.032
0.916MetArg: 0.916 ± 0.032
1.437MetSer: 1.437 ± 0.041
1.193MetThr: 1.193 ± 0.042
1.197MetVal: 1.197 ± 0.031
0.178MetTrp: 0.178 ± 0.016
0.874MetTyr: 0.874 ± 0.036
0.0MetXaa: 0.0 ± 0.0
Asn
3.508AsnAla: 3.508 ± 0.059
0.505AsnCys: 0.505 ± 0.03
2.932AsnAsp: 2.932 ± 0.071
3.658AsnGlu: 3.658 ± 0.069
2.86AsnPhe: 2.86 ± 0.051
3.67AsnGly: 3.67 ± 0.095
1.05AsnHis: 1.05 ± 0.037
5.191AsnIle: 5.191 ± 0.089
4.862AsnLys: 4.862 ± 0.072
5.457AsnLeu: 5.457 ± 0.076
1.271AsnMet: 1.271 ± 0.037
4.131AsnAsn: 4.131 ± 0.093
2.646AsnPro: 2.646 ± 0.059
2.581AsnGln: 2.581 ± 0.054
2.245AsnArg: 2.245 ± 0.057
3.868AsnSer: 3.868 ± 0.087
3.69AsnThr: 3.69 ± 0.081
3.198AsnVal: 3.198 ± 0.067
0.744AsnTrp: 0.744 ± 0.027
2.851AsnTyr: 2.851 ± 0.067
0.0AsnXaa: 0.0 ± 0.0
Pro
1.911ProAla: 1.911 ± 0.056
0.23ProCys: 0.23 ± 0.015
2.061ProAsp: 2.061 ± 0.045
2.676ProGlu: 2.676 ± 0.06
1.985ProPhe: 1.985 ± 0.046
1.814ProGly: 1.814 ± 0.057
0.626ProHis: 0.626 ± 0.028
2.557ProIle: 2.557 ± 0.049
2.24ProLys: 2.24 ± 0.052
2.806ProLeu: 2.806 ± 0.058
0.742ProMet: 0.742 ± 0.031
1.903ProAsn: 1.903 ± 0.047
0.799ProPro: 0.799 ± 0.033
1.199ProGln: 1.199 ± 0.038
0.827ProArg: 0.827 ± 0.031
1.99ProSer: 1.99 ± 0.045
1.857ProThr: 1.857 ± 0.055
2.541ProVal: 2.541 ± 0.055
0.257ProTrp: 0.257 ± 0.018
1.455ProTyr: 1.455 ± 0.038
0.0ProXaa: 0.0 ± 0.0
Gln
2.172GlnAla: 2.172 ± 0.057
0.186GlnCys: 0.186 ± 0.016
1.667GlnAsp: 1.667 ± 0.054
2.501GlnGlu: 2.501 ± 0.061
1.705GlnPhe: 1.705 ± 0.04
1.986GlnGly: 1.986 ± 0.055
0.618GlnHis: 0.618 ± 0.027
3.023GlnIle: 3.023 ± 0.067
3.468GlnLys: 3.468 ± 0.074
3.467GlnLeu: 3.467 ± 0.073
0.896GlnMet: 0.896 ± 0.032
2.611GlnAsn: 2.611 ± 0.064
1.106GlnPro: 1.106 ± 0.038
1.657GlnGln: 1.657 ± 0.049
1.276GlnArg: 1.276 ± 0.042
2.14GlnSer: 2.14 ± 0.052
2.221GlnThr: 2.221 ± 0.053
2.038GlnVal: 2.038 ± 0.046
0.451GlnTrp: 0.451 ± 0.023
1.676GlnTyr: 1.676 ± 0.037
0.0GlnXaa: 0.0 ± 0.0
Arg
1.872ArgAla: 1.872 ± 0.045
0.207ArgCys: 0.207 ± 0.016
1.563ArgAsp: 1.563 ± 0.05
2.374ArgGlu: 2.374 ± 0.064
1.912ArgPhe: 1.912 ± 0.056
1.9ArgGly: 1.9 ± 0.053
0.542ArgHis: 0.542 ± 0.025
3.014ArgIle: 3.014 ± 0.061
2.763ArgLys: 2.763 ± 0.075
3.23ArgLeu: 3.23 ± 0.067
0.951ArgMet: 0.951 ± 0.032
2.006ArgAsn: 2.006 ± 0.051
0.98ArgPro: 0.98 ± 0.036
1.181ArgGln: 1.181 ± 0.037
1.224ArgArg: 1.224 ± 0.043
1.841ArgSer: 1.841 ± 0.046
1.95ArgThr: 1.95 ± 0.048
2.059ArgVal: 2.059 ± 0.047
0.435ArgTrp: 0.435 ± 0.023
1.543ArgTyr: 1.543 ± 0.044
0.0ArgXaa: 0.0 ± 0.0
Ser
3.77SerAla: 3.77 ± 0.06
0.675SerCys: 0.675 ± 0.03
3.59SerAsp: 3.59 ± 0.076
4.004SerGlu: 4.004 ± 0.066
3.895SerPhe: 3.895 ± 0.07
4.658SerGly: 4.658 ± 0.109
1.056SerHis: 1.056 ± 0.038
5.073SerIle: 5.073 ± 0.081
4.667SerLys: 4.667 ± 0.075
5.943SerLeu: 5.943 ± 0.084
1.266SerMet: 1.266 ± 0.04
3.626SerAsn: 3.626 ± 0.075
2.112SerPro: 2.112 ± 0.06
2.13SerGln: 2.13 ± 0.051
1.963SerArg: 1.963 ± 0.051
4.508SerSer: 4.508 ± 0.158
3.403SerThr: 3.403 ± 0.084
4.217SerVal: 4.217 ± 0.075
0.688SerTrp: 0.688 ± 0.028
2.891SerTyr: 2.891 ± 0.075
0.0SerXaa: 0.0 ± 0.0
Thr
3.909ThrAla: 3.909 ± 0.086
0.393ThrCys: 0.393 ± 0.025
3.244ThrAsp: 3.244 ± 0.08
3.757ThrGlu: 3.757 ± 0.068
2.756ThrPhe: 2.756 ± 0.058
4.061ThrGly: 4.061 ± 0.097
1.031ThrHis: 1.031 ± 0.041
4.751ThrIle: 4.751 ± 0.077
3.669ThrLys: 3.669 ± 0.072
5.249ThrLeu: 5.249 ± 0.087
0.994ThrMet: 0.994 ± 0.033
3.06ThrAsn: 3.06 ± 0.07
2.404ThrPro: 2.404 ± 0.059
2.05ThrGln: 2.05 ± 0.054
1.514ThrArg: 1.514 ± 0.044
3.635ThrSer: 3.635 ± 0.09
3.442ThrThr: 3.442 ± 0.108
3.884ThrVal: 3.884 ± 0.085
0.482ThrTrp: 0.482 ± 0.022
2.424ThrTyr: 2.424 ± 0.071
0.0ThrXaa: 0.0 ± 0.0
Val
3.662ValAla: 3.662 ± 0.075
0.588ValCys: 0.588 ± 0.03
3.298ValAsp: 3.298 ± 0.065
4.051ValGlu: 4.051 ± 0.07
3.545ValPhe: 3.545 ± 0.071
3.697ValGly: 3.697 ± 0.078
0.953ValHis: 0.953 ± 0.033
4.973ValIle: 4.973 ± 0.086
4.528ValLys: 4.528 ± 0.082
6.242ValLeu: 6.242 ± 0.092
1.274ValMet: 1.274 ± 0.043
3.626ValAsn: 3.626 ± 0.065
2.009ValPro: 2.009 ± 0.051
2.035ValGln: 2.035 ± 0.043
2.083ValArg: 2.083 ± 0.053
4.163ValSer: 4.163 ± 0.074
3.34ValThr: 3.34 ± 0.083
4.19ValVal: 4.19 ± 0.083
0.574ValTrp: 0.574 ± 0.023
2.685ValTyr: 2.685 ± 0.061
0.0ValXaa: 0.0 ± 0.0
Trp
0.538TrpAla: 0.538 ± 0.026
0.099TrpCys: 0.099 ± 0.01
0.584TrpAsp: 0.584 ± 0.023
0.854TrpGlu: 0.854 ± 0.052
0.514TrpPhe: 0.514 ± 0.024
0.656TrpGly: 0.656 ± 0.025
0.283TrpHis: 0.283 ± 0.023
0.823TrpIle: 0.823 ± 0.027
0.83TrpLys: 0.83 ± 0.032
0.995TrpLeu: 0.995 ± 0.035
0.284TrpMet: 0.284 ± 0.016
0.691TrpAsn: 0.691 ± 0.026
0.141TrpPro: 0.141 ± 0.013
0.406TrpGln: 0.406 ± 0.02
0.374TrpArg: 0.374 ± 0.024
0.609TrpSer: 0.609 ± 0.028
0.606TrpThr: 0.606 ± 0.028
0.594TrpVal: 0.594 ± 0.025
0.122TrpTrp: 0.122 ± 0.011
0.43TrpTyr: 0.43 ± 0.023
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.545TyrAla: 2.545 ± 0.059
0.339TyrCys: 0.339 ± 0.022
2.32TyrAsp: 2.32 ± 0.06
2.786TyrGlu: 2.786 ± 0.06
2.614TyrPhe: 2.614 ± 0.053
2.681TyrGly: 2.681 ± 0.062
0.882TyrHis: 0.882 ± 0.029
3.376TyrIle: 3.376 ± 0.069
3.276TyrLys: 3.276 ± 0.07
4.068TyrLeu: 4.068 ± 0.076
0.811TyrMet: 0.811 ± 0.028
2.779TyrAsn: 2.779 ± 0.063
1.557TyrPro: 1.557 ± 0.05
1.769TyrGln: 1.769 ± 0.042
1.797TyrArg: 1.797 ± 0.043
2.914TyrSer: 2.914 ± 0.065
2.553TyrThr: 2.553 ± 0.064
2.465TyrVal: 2.465 ± 0.063
0.488TyrTrp: 0.488 ± 0.026
2.441TyrTyr: 2.441 ± 0.066
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2689 proteins (898407 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski