Amino acid dipepetide frequency for Desulfomicrobium baculatum (strain DSM 4028 / VKM B-1378 / X) (Desulfovibrio baculatus)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
10.417AlaAla: 10.417 ± 0.154
1.357AlaCys: 1.357 ± 0.042
5.054AlaAsp: 5.054 ± 0.095
6.015AlaGlu: 6.015 ± 0.078
3.618AlaPhe: 3.618 ± 0.064
8.551AlaGly: 8.551 ± 0.154
1.985AlaHis: 1.985 ± 0.041
4.725AlaIle: 4.725 ± 0.075
4.06AlaLys: 4.06 ± 0.079
11.366AlaLeu: 11.366 ± 0.131
3.117AlaMet: 3.117 ± 0.062
2.42AlaAsn: 2.42 ± 0.048
3.846AlaPro: 3.846 ± 0.069
3.726AlaGln: 3.726 ± 0.054
6.35AlaArg: 6.35 ± 0.09
5.487AlaSer: 5.487 ± 0.092
4.509AlaThr: 4.509 ± 0.083
7.182AlaVal: 7.182 ± 0.115
1.249AlaTrp: 1.249 ± 0.033
2.347AlaTyr: 2.347 ± 0.044
0.0AlaXaa: 0.0 ± 0.0
Cys
1.308CysAla: 1.308 ± 0.036
0.245CysCys: 0.245 ± 0.016
0.594CysAsp: 0.594 ± 0.023
0.63CysGlu: 0.63 ± 0.024
0.47CysPhe: 0.47 ± 0.022
1.369CysGly: 1.369 ± 0.04
0.413CysHis: 0.413 ± 0.027
0.643CysIle: 0.643 ± 0.025
0.47CysLys: 0.47 ± 0.018
1.442CysLeu: 1.442 ± 0.041
0.33CysMet: 0.33 ± 0.018
0.316CysAsn: 0.316 ± 0.017
0.909CysPro: 0.909 ± 0.032
0.354CysGln: 0.354 ± 0.018
0.909CysArg: 0.909 ± 0.026
0.79CysSer: 0.79 ± 0.03
0.627CysThr: 0.627 ± 0.025
0.972CysVal: 0.972 ± 0.031
0.143CysTrp: 0.143 ± 0.011
0.283CysTyr: 0.283 ± 0.015
0.0CysXaa: 0.0 ± 0.0
Asp
4.875AspAla: 4.875 ± 0.076
0.673AspCys: 0.673 ± 0.029
2.812AspAsp: 2.812 ± 0.095
3.547AspGlu: 3.547 ± 0.063
2.593AspPhe: 2.593 ± 0.05
4.445AspGly: 4.445 ± 0.192
1.196AspHis: 1.196 ± 0.03
3.404AspIle: 3.404 ± 0.063
2.311AspLys: 2.311 ± 0.054
6.322AspLeu: 6.322 ± 0.079
1.604AspMet: 1.604 ± 0.04
1.597AspAsn: 1.597 ± 0.044
2.879AspPro: 2.879 ± 0.054
1.737AspGln: 1.737 ± 0.038
3.202AspArg: 3.202 ± 0.059
3.037AspSer: 3.037 ± 0.084
2.747AspThr: 2.747 ± 0.141
3.915AspVal: 3.915 ± 0.064
0.776AspTrp: 0.776 ± 0.027
1.57AspTyr: 1.57 ± 0.043
0.0AspXaa: 0.0 ± 0.0
Glu
6.236GluAla: 6.236 ± 0.079
0.635GluCys: 0.635 ± 0.025
3.235GluAsp: 3.235 ± 0.056
4.386GluGlu: 4.386 ± 0.079
2.373GluPhe: 2.373 ± 0.048
3.935GluGly: 3.935 ± 0.065
1.463GluHis: 1.463 ± 0.035
4.027GluIle: 4.027 ± 0.073
3.406GluLys: 3.406 ± 0.066
6.95GluLeu: 6.95 ± 0.092
1.862GluMet: 1.862 ± 0.042
2.42GluAsn: 2.42 ± 0.045
2.357GluPro: 2.357 ± 0.048
2.439GluGln: 2.439 ± 0.057
4.235GluArg: 4.235 ± 0.067
3.276GluSer: 3.276 ± 0.052
3.09GluThr: 3.09 ± 0.052
4.179GluVal: 4.179 ± 0.063
0.651GluTrp: 0.651 ± 0.023
1.62GluTyr: 1.62 ± 0.036
0.0GluXaa: 0.0 ± 0.0
Phe
3.687PheAla: 3.687 ± 0.064
0.653PheCys: 0.653 ± 0.024
2.472PheAsp: 2.472 ± 0.049
2.438PheGlu: 2.438 ± 0.041
2.098PhePhe: 2.098 ± 0.054
3.314PheGly: 3.314 ± 0.055
0.862PheHis: 0.862 ± 0.023
2.07PheIle: 2.07 ± 0.051
1.509PheLys: 1.509 ± 0.042
4.649PheLeu: 4.649 ± 0.087
1.141PheMet: 1.141 ± 0.036
1.276PheAsn: 1.276 ± 0.032
1.81PhePro: 1.81 ± 0.043
1.19PheGln: 1.19 ± 0.034
2.231PheArg: 2.231 ± 0.049
2.986PheSer: 2.986 ± 0.056
2.16PheThr: 2.16 ± 0.044
3.036PheVal: 3.036 ± 0.056
0.639PheTrp: 0.639 ± 0.027
1.039PheTyr: 1.039 ± 0.034
0.0PheXaa: 0.0 ± 0.0
Gly
6.979GlyAla: 6.979 ± 0.139
1.263GlyCys: 1.263 ± 0.036
4.048GlyAsp: 4.048 ± 0.187
4.739GlyGlu: 4.739 ± 0.073
3.498GlyPhe: 3.498 ± 0.06
6.61GlyGly: 6.61 ± 0.264
1.87GlyHis: 1.87 ± 0.044
4.842GlyIle: 4.842 ± 0.071
3.958GlyLys: 3.958 ± 0.07
9.164GlyLeu: 9.164 ± 0.113
2.54GlyMet: 2.54 ± 0.05
2.448GlyAsn: 2.448 ± 0.122
2.743GlyPro: 2.743 ± 0.056
3.135GlyGln: 3.135 ± 0.049
5.084GlyArg: 5.084 ± 0.083
4.509GlySer: 4.509 ± 0.122
4.142GlyThr: 4.142 ± 0.087
6.098GlyVal: 6.098 ± 0.086
1.081GlyTrp: 1.081 ± 0.04
2.308GlyTyr: 2.308 ± 0.042
0.0GlyXaa: 0.0 ± 0.0
His
2.074HisAla: 2.074 ± 0.048
0.338HisCys: 0.338 ± 0.017
1.298HisAsp: 1.298 ± 0.037
1.388HisGlu: 1.388 ± 0.034
1.01HisPhe: 1.01 ± 0.033
1.998HisGly: 1.998 ± 0.048
0.588HisHis: 0.588 ± 0.026
1.139HisIle: 1.139 ± 0.033
0.778HisLys: 0.778 ± 0.025
2.343HisLeu: 2.343 ± 0.047
0.5HisMet: 0.5 ± 0.02
0.596HisAsn: 0.596 ± 0.026
1.332HisPro: 1.332 ± 0.036
0.692HisGln: 0.692 ± 0.023
1.235HisArg: 1.235 ± 0.037
1.177HisSer: 1.177 ± 0.03
0.942HisThr: 0.942 ± 0.031
1.521HisVal: 1.521 ± 0.039
0.248HisTrp: 0.248 ± 0.013
0.617HisTyr: 0.617 ± 0.026
0.0HisXaa: 0.0 ± 0.0
Ile
4.982IleAla: 4.982 ± 0.072
0.755IleCys: 0.755 ± 0.026
2.932IleAsp: 2.932 ± 0.057
3.237IleGlu: 3.237 ± 0.052
2.416IlePhe: 2.416 ± 0.049
4.263IleGly: 4.263 ± 0.084
1.138IleHis: 1.138 ± 0.032
3.155IleIle: 3.155 ± 0.066
2.305IleLys: 2.305 ± 0.053
6.346IleLeu: 6.346 ± 0.084
1.534IleMet: 1.534 ± 0.038
1.765IleAsn: 1.765 ± 0.039
2.878IlePro: 2.878 ± 0.052
1.645IleGln: 1.645 ± 0.039
3.568IleArg: 3.568 ± 0.056
3.563IleSer: 3.563 ± 0.063
2.987IleThr: 2.987 ± 0.068
4.024IleVal: 4.024 ± 0.067
0.608IleTrp: 0.608 ± 0.025
1.382IleTyr: 1.382 ± 0.035
0.0IleXaa: 0.0 ± 0.0
Lys
4.257LysAla: 4.257 ± 0.071
0.429LysCys: 0.429 ± 0.021
2.552LysAsp: 2.552 ± 0.063
2.778LysGlu: 2.778 ± 0.065
1.441LysPhe: 1.441 ± 0.038
3.196LysGly: 3.196 ± 0.064
0.814LysHis: 0.814 ± 0.029
2.738LysIle: 2.738 ± 0.057
2.613LysLys: 2.613 ± 0.065
3.74LysLeu: 3.74 ± 0.07
1.163LysMet: 1.163 ± 0.033
1.799LysAsn: 1.799 ± 0.046
1.927LysPro: 1.927 ± 0.042
1.321LysGln: 1.321 ± 0.038
2.451LysArg: 2.451 ± 0.052
2.49LysSer: 2.49 ± 0.055
2.448LysThr: 2.448 ± 0.045
2.899LysVal: 2.899 ± 0.056
0.42LysTrp: 0.42 ± 0.023
1.118LysTyr: 1.118 ± 0.038
0.0LysXaa: 0.0 ± 0.0
Leu
12.182LeuAla: 12.182 ± 0.149
1.529LeuCys: 1.529 ± 0.044
6.639LeuAsp: 6.639 ± 0.095
6.885LeuGlu: 6.885 ± 0.08
4.363LeuPhe: 4.363 ± 0.081
9.401LeuGly: 9.401 ± 0.11
2.312LeuHis: 2.312 ± 0.046
5.111LeuIle: 5.111 ± 0.078
4.428LeuLys: 4.428 ± 0.072
11.188LeuLeu: 11.188 ± 0.15
2.457LeuMet: 2.457 ± 0.052
2.904LeuAsn: 2.904 ± 0.048
5.607LeuPro: 5.607 ± 0.103
3.352LeuGln: 3.352 ± 0.059
7.113LeuArg: 7.113 ± 0.116
6.795LeuSer: 6.795 ± 0.091
5.782LeuThr: 5.782 ± 0.09
7.658LeuVal: 7.658 ± 0.092
1.161LeuTrp: 1.161 ± 0.035
2.373LeuTyr: 2.373 ± 0.064
0.0LeuXaa: 0.0 ± 0.0
Met
3.051MetAla: 3.051 ± 0.06
0.271MetCys: 0.271 ± 0.015
1.724MetAsp: 1.724 ± 0.038
1.673MetGlu: 1.673 ± 0.046
0.864MetPhe: 0.864 ± 0.027
2.157MetGly: 2.157 ± 0.046
0.714MetHis: 0.714 ± 0.026
1.468MetIle: 1.468 ± 0.041
1.249MetLys: 1.249 ± 0.037
2.726MetLeu: 2.726 ± 0.056
0.525MetMet: 0.525 ± 0.021
1.17MetAsn: 1.17 ± 0.032
1.4MetPro: 1.4 ± 0.031
0.973MetGln: 0.973 ± 0.03
1.729MetArg: 1.729 ± 0.037
1.731MetSer: 1.731 ± 0.039
1.678MetThr: 1.678 ± 0.039
1.845MetVal: 1.845 ± 0.045
0.187MetTrp: 0.187 ± 0.013
0.506MetTyr: 0.506 ± 0.022
0.0MetXaa: 0.0 ± 0.0
Asn
2.794AsnAla: 2.794 ± 0.057
0.381AsnCys: 0.381 ± 0.017
1.627AsnAsp: 1.627 ± 0.113
1.526AsnGlu: 1.526 ± 0.041
1.33AsnPhe: 1.33 ± 0.034
2.11AsnGly: 2.11 ± 0.058
0.62AsnHis: 0.62 ± 0.027
2.023AsnIle: 2.023 ± 0.046
1.125AsnLys: 1.125 ± 0.037
3.521AsnLeu: 3.521 ± 0.056
0.937AsnMet: 0.937 ± 0.03
0.941AsnAsn: 0.941 ± 0.044
2.032AsnPro: 2.032 ± 0.044
0.966AsnGln: 0.966 ± 0.03
1.671AsnArg: 1.671 ± 0.041
1.654AsnSer: 1.654 ± 0.046
1.544AsnThr: 1.544 ± 0.044
2.236AsnVal: 2.236 ± 0.061
0.383AsnTrp: 0.383 ± 0.016
0.815AsnTyr: 0.815 ± 0.031
0.0AsnXaa: 0.0 ± 0.0
Pro
4.722ProAla: 4.722 ± 0.09
0.601ProCys: 0.601 ± 0.024
3.149ProAsp: 3.149 ± 0.061
4.002ProGlu: 4.002 ± 0.062
1.941ProPhe: 1.941 ± 0.048
4.288ProGly: 4.288 ± 0.071
0.932ProHis: 0.932 ± 0.033
1.886ProIle: 1.886 ± 0.043
1.869ProLys: 1.869 ± 0.045
4.616ProLeu: 4.616 ± 0.072
1.184ProMet: 1.184 ± 0.031
1.138ProAsn: 1.138 ± 0.037
1.793ProPro: 1.793 ± 0.049
1.609ProGln: 1.609 ± 0.04
2.422ProArg: 2.422 ± 0.055
2.536ProSer: 2.536 ± 0.05
1.915ProThr: 1.915 ± 0.043
3.957ProVal: 3.957 ± 0.068
0.635ProTrp: 0.635 ± 0.026
1.122ProTyr: 1.122 ± 0.035
0.0ProXaa: 0.0 ± 0.0
Gln
4.119GlnAla: 4.119 ± 0.072
0.363GlnCys: 0.363 ± 0.02
1.965GlnAsp: 1.965 ± 0.043
2.408GlnGlu: 2.408 ± 0.05
1.082GlnPhe: 1.082 ± 0.03
2.944GlnGly: 2.944 ± 0.058
0.616GlnHis: 0.616 ± 0.023
1.923GlnIle: 1.923 ± 0.041
1.555GlnLys: 1.555 ± 0.042
2.913GlnLeu: 2.913 ± 0.054
0.911GlnMet: 0.911 ± 0.029
1.212GlnAsn: 1.212 ± 0.035
1.324GlnPro: 1.324 ± 0.037
1.165GlnGln: 1.165 ± 0.035
2.002GlnArg: 2.002 ± 0.05
2.049GlnSer: 2.049 ± 0.046
1.935GlnThr: 1.935 ± 0.043
2.508GlnVal: 2.508 ± 0.045
0.384GlnTrp: 0.384 ± 0.018
0.784GlnTyr: 0.784 ± 0.026
0.0GlnXaa: 0.0 ± 0.0
Arg
5.244ArgAla: 5.244 ± 0.081
0.714ArgCys: 0.714 ± 0.027
3.418ArgAsp: 3.418 ± 0.053
4.634ArgGlu: 4.634 ± 0.08
2.801ArgPhe: 2.801 ± 0.053
3.899ArgGly: 3.899 ± 0.07
1.596ArgHis: 1.596 ± 0.044
4.288ArgIle: 4.288 ± 0.055
2.939ArgLys: 2.939 ± 0.056
7.033ArgLeu: 7.033 ± 0.099
1.801ArgMet: 1.801 ± 0.043
1.878ArgAsn: 1.878 ± 0.041
2.682ArgPro: 2.682 ± 0.059
2.542ArgGln: 2.542 ± 0.047
3.938ArgArg: 3.938 ± 0.078
3.36ArgSer: 3.36 ± 0.057
3.168ArgThr: 3.168 ± 0.051
4.124ArgVal: 4.124 ± 0.069
0.666ArgTrp: 0.666 ± 0.026
1.643ArgTyr: 1.643 ± 0.039
0.0ArgXaa: 0.0 ± 0.0
Ser
5.327SerAla: 5.327 ± 0.09
0.832SerCys: 0.832 ± 0.028
2.798SerAsp: 2.798 ± 0.058
3.223SerGlu: 3.223 ± 0.063
2.586SerPhe: 2.586 ± 0.051
5.459SerGly: 5.459 ± 0.111
1.222SerHis: 1.222 ± 0.033
3.374SerIle: 3.374 ± 0.065
2.173SerLys: 2.173 ± 0.047
6.704SerLeu: 6.704 ± 0.093
1.877SerMet: 1.877 ± 0.041
1.46SerAsn: 1.46 ± 0.042
2.863SerPro: 2.863 ± 0.045
1.837SerGln: 1.837 ± 0.041
3.789SerArg: 3.789 ± 0.067
3.618SerSer: 3.618 ± 0.082
2.911SerThr: 2.911 ± 0.079
4.256SerVal: 4.256 ± 0.077
0.798SerTrp: 0.798 ± 0.029
1.452SerTyr: 1.452 ± 0.038
0.0SerXaa: 0.0 ± 0.0
Thr
4.928ThrAla: 4.928 ± 0.102
0.614ThrCys: 0.614 ± 0.021
2.675ThrAsp: 2.675 ± 0.064
2.735ThrGlu: 2.735 ± 0.058
1.968ThrPhe: 1.968 ± 0.038
4.902ThrGly: 4.902 ± 0.108
1.07ThrHis: 1.07 ± 0.03
2.785ThrIle: 2.785 ± 0.062
1.771ThrLys: 1.771 ± 0.042
6.018ThrLeu: 6.018 ± 0.115
1.259ThrMet: 1.259 ± 0.031
1.372ThrAsn: 1.372 ± 0.033
2.873ThrPro: 2.873 ± 0.058
1.626ThrGln: 1.626 ± 0.043
2.959ThrArg: 2.959 ± 0.057
2.835ThrSer: 2.835 ± 0.068
2.688ThrThr: 2.688 ± 0.072
4.125ThrVal: 4.125 ± 0.083
0.583ThrTrp: 0.583 ± 0.025
1.274ThrTyr: 1.274 ± 0.031
0.0ThrXaa: 0.0 ± 0.0
Val
6.816ValAla: 6.816 ± 0.102
1.071ValCys: 1.071 ± 0.034
4.204ValAsp: 4.204 ± 0.07
4.417ValGlu: 4.417 ± 0.069
3.134ValPhe: 3.134 ± 0.054
5.239ValGly: 5.239 ± 0.096
1.591ValHis: 1.591 ± 0.037
4.024ValIle: 4.024 ± 0.063
2.576ValLys: 2.576 ± 0.052
8.158ValLeu: 8.158 ± 0.101
1.947ValMet: 1.947 ± 0.042
2.29ValAsn: 2.29 ± 0.057
3.219ValPro: 3.219 ± 0.058
2.504ValGln: 2.504 ± 0.044
5.005ValArg: 5.005 ± 0.077
4.392ValSer: 4.392 ± 0.076
3.942ValThr: 3.942 ± 0.084
5.559ValVal: 5.559 ± 0.096
0.773ValTrp: 0.773 ± 0.03
1.725ValTyr: 1.725 ± 0.035
0.0ValXaa: 0.0 ± 0.0
Trp
1.013TrpAla: 1.013 ± 0.035
0.13TrpCys: 0.13 ± 0.012
0.643TrpAsp: 0.643 ± 0.025
0.691TrpGlu: 0.691 ± 0.027
0.509TrpPhe: 0.509 ± 0.025
0.868TrpGly: 0.868 ± 0.035
0.282TrpHis: 0.282 ± 0.016
0.725TrpIle: 0.725 ± 0.03
0.571TrpLys: 0.571 ± 0.025
1.227TrpLeu: 1.227 ± 0.04
0.342TrpMet: 0.342 ± 0.017
0.476TrpAsn: 0.476 ± 0.02
0.603TrpPro: 0.603 ± 0.024
0.493TrpGln: 0.493 ± 0.018
0.819TrpArg: 0.819 ± 0.028
0.715TrpSer: 0.715 ± 0.029
0.657TrpThr: 0.657 ± 0.022
0.766TrpVal: 0.766 ± 0.029
0.182TrpTrp: 0.182 ± 0.013
0.253TrpTyr: 0.253 ± 0.016
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.374TyrAla: 2.374 ± 0.046
0.362TyrCys: 0.362 ± 0.017
1.404TyrAsp: 1.404 ± 0.035
1.422TyrGlu: 1.422 ± 0.036
1.167TyrPhe: 1.167 ± 0.037
2.109TyrGly: 2.109 ± 0.064
0.529TyrHis: 0.529 ± 0.022
1.131TyrIle: 1.131 ± 0.032
0.927TyrLys: 0.927 ± 0.033
2.813TyrLeu: 2.813 ± 0.051
0.61TyrMet: 0.61 ± 0.022
0.76TyrAsn: 0.76 ± 0.027
1.241TyrPro: 1.241 ± 0.028
0.855TyrGln: 0.855 ± 0.027
1.656TyrArg: 1.656 ± 0.042
1.562TyrSer: 1.562 ± 0.042
1.188TyrThr: 1.188 ± 0.032
1.725TyrVal: 1.725 ± 0.04
0.394TyrTrp: 0.394 ± 0.019
0.821TyrTyr: 0.821 ± 0.026
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3421 proteins (1171290 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski