Amino acid dipepetide frequency for Simian foamy virus type 1 (SFVmac) (SFV-1)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.009AlaAla: 6.009 ± 3.286
0.858AlaCys: 0.858 ± 0.496
3.72AlaAsp: 3.72 ± 0.356
3.147AlaGlu: 3.147 ± 1.125
1.431AlaPhe: 1.431 ± 0.466
2.861AlaGly: 2.861 ± 1.204
2.003AlaHis: 2.003 ± 0.822
2.003AlaIle: 2.003 ± 0.704
2.575AlaLys: 2.575 ± 1.051
6.867AlaLeu: 6.867 ± 0.752
2.003AlaMet: 2.003 ± 0.485
3.433AlaAsn: 3.433 ± 0.51
4.292AlaPro: 4.292 ± 2.325
3.72AlaGln: 3.72 ± 0.764
4.006AlaArg: 4.006 ± 1.682
4.864AlaSer: 4.864 ± 1.771
4.864AlaThr: 4.864 ± 0.204
4.006AlaVal: 4.006 ± 1.273
0.286AlaTrp: 0.286 ± 0.29
2.289AlaTyr: 2.289 ± 0.517
0.0AlaXaa: 0.0 ± 0.0
Cys
0.286CysAla: 0.286 ± 0.235
0.286CysCys: 0.286 ± 0.235
0.858CysAsp: 0.858 ± 0.689
0.572CysGlu: 0.572 ± 0.723
1.144CysPhe: 1.144 ± 0.688
1.144CysGly: 1.144 ± 0.678
0.0CysHis: 0.0 ± 0.0
1.431CysIle: 1.431 ± 0.722
1.717CysLys: 1.717 ± 0.909
2.003CysLeu: 2.003 ± 0.871
0.572CysMet: 0.572 ± 0.366
1.431CysAsn: 1.431 ± 0.432
0.572CysPro: 0.572 ± 0.471
0.286CysGln: 0.286 ± 0.362
0.572CysArg: 0.572 ± 0.339
1.144CysSer: 1.144 ± 0.941
0.0CysThr: 0.0 ± 0.0
0.572CysVal: 0.572 ± 0.234
0.858CysTrp: 0.858 ± 0.294
0.572CysTyr: 0.572 ± 0.366
0.0CysXaa: 0.0 ± 0.0
Asp
2.003AspAla: 2.003 ± 0.423
0.858AspCys: 0.858 ± 0.706
2.003AspAsp: 2.003 ± 0.396
2.861AspGlu: 2.861 ± 0.693
1.144AspPhe: 1.144 ± 0.941
0.858AspGly: 0.858 ± 0.4
1.717AspHis: 1.717 ± 0.941
2.575AspIle: 2.575 ± 0.921
1.717AspLys: 1.717 ± 0.491
5.15AspLeu: 5.15 ± 1.102
0.858AspMet: 0.858 ± 0.447
2.289AspAsn: 2.289 ± 0.755
4.292AspPro: 4.292 ± 1.627
4.006AspGln: 4.006 ± 0.989
1.431AspArg: 1.431 ± 0.316
2.289AspSer: 2.289 ± 0.906
1.144AspThr: 1.144 ± 0.468
4.006AspVal: 4.006 ± 0.746
2.289AspTrp: 2.289 ± 0.86
2.289AspTyr: 2.289 ± 0.234
0.0AspXaa: 0.0 ± 0.0
Glu
2.861GluAla: 2.861 ± 0.307
1.144GluCys: 1.144 ± 0.636
3.433GluAsp: 3.433 ± 1.027
4.578GluGlu: 4.578 ± 1.072
2.575GluPhe: 2.575 ± 0.61
5.15GluGly: 5.15 ± 1.479
0.858GluHis: 0.858 ± 0.31
4.292GluIle: 4.292 ± 0.564
2.861GluLys: 2.861 ± 1.16
4.864GluLeu: 4.864 ± 1.789
1.717GluMet: 1.717 ± 0.979
3.433GluAsn: 3.433 ± 1.168
1.431GluPro: 1.431 ± 0.808
2.289GluGln: 2.289 ± 0.464
4.006GluArg: 4.006 ± 1.161
2.289GluSer: 2.289 ± 0.459
2.289GluThr: 2.289 ± 1.072
3.72GluVal: 3.72 ± 0.99
0.286GluTrp: 0.286 ± 0.235
1.717GluTyr: 1.717 ± 0.683
0.0GluXaa: 0.0 ± 0.0
Phe
2.861PheAla: 2.861 ± 0.828
0.286PheCys: 0.286 ± 0.235
0.858PheAsp: 0.858 ± 0.371
0.858PheGlu: 0.858 ± 0.489
0.286PhePhe: 0.286 ± 0.362
2.003PheGly: 2.003 ± 0.731
0.858PheHis: 0.858 ± 0.294
1.717PheIle: 1.717 ± 0.702
1.144PheLys: 1.144 ± 0.362
3.72PheLeu: 3.72 ± 0.667
0.0PheMet: 0.0 ± 0.0
0.572PheAsn: 0.572 ± 0.275
2.003PhePro: 2.003 ± 1.069
0.572PheGln: 0.572 ± 0.366
0.572PheArg: 0.572 ± 0.339
2.003PheSer: 2.003 ± 0.568
2.003PheThr: 2.003 ± 0.619
1.144PheVal: 1.144 ± 0.369
0.858PheTrp: 0.858 ± 0.31
1.717PheTyr: 1.717 ± 0.702
0.0PheXaa: 0.0 ± 0.0
Gly
2.289GlyAla: 2.289 ± 0.919
0.286GlyCys: 0.286 ± 0.235
3.433GlyAsp: 3.433 ± 1.098
2.289GlyGlu: 2.289 ± 0.908
3.147GlyPhe: 3.147 ± 0.976
3.147GlyGly: 3.147 ± 2.247
2.003GlyHis: 2.003 ± 0.623
3.147GlyIle: 3.147 ± 0.827
2.289GlyLys: 2.289 ± 0.975
2.861GlyLeu: 2.861 ± 0.81
1.717GlyMet: 1.717 ± 0.73
4.006GlyAsn: 4.006 ± 1.682
4.578GlyPro: 4.578 ± 2.037
3.72GlyGln: 3.72 ± 2.35
4.864GlyArg: 4.864 ± 2.85
4.292GlySer: 4.292 ± 1.25
2.861GlyThr: 2.861 ± 0.963
2.861GlyVal: 2.861 ± 0.831
1.144GlyTrp: 1.144 ± 0.65
2.289GlyTyr: 2.289 ± 0.56
0.0GlyXaa: 0.0 ± 0.0
His
1.717HisAla: 1.717 ± 1.75
0.858HisCys: 0.858 ± 0.225
0.858HisAsp: 0.858 ± 0.294
1.431HisGlu: 1.431 ± 0.448
0.286HisPhe: 0.286 ± 0.318
1.144HisGly: 1.144 ± 0.369
0.286HisHis: 0.286 ± 0.318
0.858HisIle: 0.858 ± 0.225
1.144HisLys: 1.144 ± 0.362
3.433HisLeu: 3.433 ± 1.299
0.0HisMet: 0.0 ± 0.0
0.572HisAsn: 0.572 ± 0.43
3.147HisPro: 3.147 ± 0.701
2.289HisGln: 2.289 ± 0.663
1.431HisArg: 1.431 ± 0.801
1.431HisSer: 1.431 ± 0.697
1.144HisThr: 1.144 ± 0.575
1.717HisVal: 1.717 ± 0.834
0.858HisTrp: 0.858 ± 0.5
1.144HisTyr: 1.144 ± 0.565
0.0HisXaa: 0.0 ± 0.0
Ile
4.578IleAla: 4.578 ± 1.425
1.144IleCys: 1.144 ± 0.732
2.575IleAsp: 2.575 ± 1.178
1.144IleGlu: 1.144 ± 0.65
1.144IlePhe: 1.144 ± 0.412
3.147IleGly: 3.147 ± 0.849
0.572IleHis: 0.572 ± 0.234
3.433IleIle: 3.433 ± 1.195
3.72IleLys: 3.72 ± 1.382
4.578IleLeu: 4.578 ± 1.286
1.144IleMet: 1.144 ± 0.412
3.147IleAsn: 3.147 ± 1.522
4.864IlePro: 4.864 ± 0.912
4.864IleGln: 4.864 ± 0.873
4.292IleArg: 4.292 ± 1.032
3.433IleSer: 3.433 ± 0.62
2.861IleThr: 2.861 ± 0.781
3.72IleVal: 3.72 ± 0.991
0.286IleTrp: 0.286 ± 0.235
1.431IleTyr: 1.431 ± 0.634
0.0IleXaa: 0.0 ± 0.0
Lys
4.006LysAla: 4.006 ± 1.584
2.289LysCys: 2.289 ± 1.464
2.003LysAsp: 2.003 ± 1.049
3.433LysGlu: 3.433 ± 1.008
1.144LysPhe: 1.144 ± 0.575
2.575LysGly: 2.575 ± 0.732
1.717LysHis: 1.717 ± 0.408
2.575LysIle: 2.575 ± 0.83
3.147LysLys: 3.147 ± 0.998
4.578LysLeu: 4.578 ± 1.237
1.717LysMet: 1.717 ± 1.311
1.431LysAsn: 1.431 ± 0.576
4.292LysPro: 4.292 ± 1.872
4.292LysGln: 4.292 ± 1.472
2.575LysArg: 2.575 ± 0.9
2.861LysSer: 2.861 ± 1.185
3.147LysThr: 3.147 ± 1.178
3.72LysVal: 3.72 ± 1.07
2.003LysTrp: 2.003 ± 0.571
2.289LysTyr: 2.289 ± 0.836
0.0LysXaa: 0.0 ± 0.0
Leu
6.581LeuAla: 6.581 ± 1.115
1.144LeuCys: 1.144 ± 0.546
4.864LeuAsp: 4.864 ± 1.181
5.722LeuGlu: 5.722 ± 1.174
2.575LeuPhe: 2.575 ± 0.539
5.436LeuGly: 5.436 ± 1.707
3.433LeuHis: 3.433 ± 0.619
4.292LeuIle: 4.292 ± 1.09
7.153LeuLys: 7.153 ± 1.838
13.734LeuLeu: 13.734 ± 1.286
1.144LeuMet: 1.144 ± 0.468
4.864LeuAsn: 4.864 ± 1.339
7.153LeuPro: 7.153 ± 1.513
6.581LeuGln: 6.581 ± 1.656
5.722LeuArg: 5.722 ± 1.613
3.72LeuSer: 3.72 ± 1.071
6.867LeuThr: 6.867 ± 1.314
4.292LeuVal: 4.292 ± 0.867
1.717LeuTrp: 1.717 ± 0.678
2.861LeuTyr: 2.861 ± 0.732
0.0LeuXaa: 0.0 ± 0.0
Met
2.003MetAla: 2.003 ± 0.914
0.286MetCys: 0.286 ± 0.318
1.431MetAsp: 1.431 ± 0.433
1.431MetGlu: 1.431 ± 0.432
0.286MetPhe: 0.286 ± 0.29
0.858MetGly: 0.858 ± 0.383
0.858MetHis: 0.858 ± 0.5
0.858MetIle: 0.858 ± 0.706
1.144MetLys: 1.144 ± 0.616
1.431MetLeu: 1.431 ± 0.355
0.572MetMet: 0.572 ± 0.325
1.431MetAsn: 1.431 ± 0.316
0.858MetPro: 0.858 ± 0.489
1.717MetGln: 1.717 ± 1.741
0.572MetArg: 0.572 ± 0.339
1.144MetSer: 1.144 ± 0.678
2.003MetThr: 2.003 ± 0.619
2.003MetVal: 2.003 ± 0.883
0.286MetTrp: 0.286 ± 0.29
0.572MetTyr: 0.572 ± 0.36
0.0MetXaa: 0.0 ± 0.0
Asn
2.861AsnAla: 2.861 ± 1.141
0.572AsnCys: 0.572 ± 0.515
2.003AsnAsp: 2.003 ± 0.706
2.575AsnGlu: 2.575 ± 1.331
1.144AsnPhe: 1.144 ± 0.468
3.147AsnGly: 3.147 ± 0.858
0.858AsnHis: 0.858 ± 0.488
3.433AsnIle: 3.433 ± 0.619
2.575AsnLys: 2.575 ± 0.83
4.864AsnLeu: 4.864 ± 1.407
1.431AsnMet: 1.431 ± 0.53
3.72AsnAsn: 3.72 ± 0.851
3.72AsnPro: 3.72 ± 1.388
3.433AsnGln: 3.433 ± 1.378
1.431AsnArg: 1.431 ± 0.74
4.578AsnSer: 4.578 ± 1.617
2.289AsnThr: 2.289 ± 0.546
2.003AsnVal: 2.003 ± 0.724
0.286AsnTrp: 0.286 ± 0.235
1.431AsnTyr: 1.431 ± 0.238
0.0AsnXaa: 0.0 ± 0.0
Pro
5.436ProAla: 5.436 ± 2.292
0.572ProCys: 0.572 ± 0.339
1.431ProAsp: 1.431 ± 0.58
4.578ProGlu: 4.578 ± 1.311
1.717ProPhe: 1.717 ± 0.304
3.72ProGly: 3.72 ± 1.608
2.003ProHis: 2.003 ± 0.506
4.006ProIle: 4.006 ± 0.521
4.578ProLys: 4.578 ± 1.231
8.011ProLeu: 8.011 ± 1.165
2.861ProMet: 2.861 ± 1.379
2.289ProAsn: 2.289 ± 0.961
7.439ProPro: 7.439 ± 2.644
3.72ProGln: 3.72 ± 0.943
3.72ProArg: 3.72 ± 1.408
7.439ProSer: 7.439 ± 1.785
3.433ProThr: 3.433 ± 0.609
3.147ProVal: 3.147 ± 0.945
1.144ProTrp: 1.144 ± 0.689
3.147ProTyr: 3.147 ± 1.074
0.0ProXaa: 0.0 ± 0.0
Gln
3.147GlnAla: 3.147 ± 0.608
1.144GlnCys: 1.144 ± 0.362
2.289GlnAsp: 2.289 ± 1.041
4.864GlnGlu: 4.864 ± 0.614
1.144GlnPhe: 1.144 ± 0.565
5.15GlnGly: 5.15 ± 1.529
2.861GlnHis: 2.861 ± 0.774
3.147GlnIle: 3.147 ± 1.374
3.433GlnLys: 3.433 ± 0.836
6.295GlnLeu: 6.295 ± 1.674
0.858GlnMet: 0.858 ± 0.569
2.575GlnAsn: 2.575 ± 0.854
4.292GlnPro: 4.292 ± 2.281
4.864GlnGln: 4.864 ± 0.926
2.289GlnArg: 2.289 ± 1.305
2.861GlnSer: 2.861 ± 1.138
2.575GlnThr: 2.575 ± 0.318
3.147GlnVal: 3.147 ± 0.961
1.144GlnTrp: 1.144 ± 0.636
3.147GlnTyr: 3.147 ± 0.741
0.0GlnXaa: 0.0 ± 0.0
Arg
2.289ArgAla: 2.289 ± 1.3
0.572ArgCys: 0.572 ± 0.637
1.717ArgAsp: 1.717 ± 0.519
3.72ArgGlu: 3.72 ± 0.61
0.858ArgPhe: 0.858 ± 0.411
4.292ArgGly: 4.292 ± 2.731
1.144ArgHis: 1.144 ± 0.258
2.575ArgIle: 2.575 ± 0.457
3.147ArgLys: 3.147 ± 0.906
4.864ArgLeu: 4.864 ± 0.626
0.858ArgMet: 0.858 ± 0.225
2.003ArgAsn: 2.003 ± 0.643
4.292ArgPro: 4.292 ± 1.183
2.003ArgGln: 2.003 ± 1.016
3.433ArgArg: 3.433 ± 1.062
4.006ArgSer: 4.006 ± 1.48
2.575ArgThr: 2.575 ± 0.899
2.575ArgVal: 2.575 ± 1.063
1.144ArgTrp: 1.144 ± 0.55
1.717ArgTyr: 1.717 ± 0.498
0.0ArgXaa: 0.0 ± 0.0
Ser
5.722SerAla: 5.722 ± 1.926
1.717SerCys: 1.717 ± 0.866
4.578SerAsp: 4.578 ± 0.799
2.575SerGlu: 2.575 ± 0.601
1.717SerPhe: 1.717 ± 0.571
4.578SerGly: 4.578 ± 1.675
0.858SerHis: 0.858 ± 0.471
5.15SerIle: 5.15 ± 1.082
3.147SerLys: 3.147 ± 1.091
6.009SerLeu: 6.009 ± 0.654
0.858SerMet: 0.858 ± 0.383
2.861SerAsn: 2.861 ± 0.67
4.864SerPro: 4.864 ± 0.983
3.72SerGln: 3.72 ± 1.474
2.003SerArg: 2.003 ± 0.406
7.439SerSer: 7.439 ± 0.655
4.864SerThr: 4.864 ± 0.841
2.289SerVal: 2.289 ± 0.461
1.431SerTrp: 1.431 ± 0.448
2.861SerTyr: 2.861 ± 0.75
0.0SerXaa: 0.0 ± 0.0
Thr
5.15ThrAla: 5.15 ± 0.85
0.572ThrCys: 0.572 ± 0.36
2.003ThrAsp: 2.003 ± 0.389
2.575ThrGlu: 2.575 ± 0.631
2.003ThrPhe: 2.003 ± 0.729
2.575ThrGly: 2.575 ± 0.674
1.431ThrHis: 1.431 ± 0.66
1.431ThrIle: 1.431 ± 0.779
3.433ThrLys: 3.433 ± 1.109
5.15ThrLeu: 5.15 ± 0.479
2.289ThrMet: 2.289 ± 0.788
1.144ThrAsn: 1.144 ± 0.579
5.15ThrPro: 5.15 ± 1.136
2.575ThrGln: 2.575 ± 0.817
2.861ThrArg: 2.861 ± 0.884
6.295ThrSer: 6.295 ± 0.589
2.575ThrThr: 2.575 ± 0.397
3.433ThrVal: 3.433 ± 0.525
1.431ThrTrp: 1.431 ± 0.508
1.144ThrTyr: 1.144 ± 0.369
0.0ThrXaa: 0.0 ± 0.0
Val
3.147ValAla: 3.147 ± 0.942
0.572ValCys: 0.572 ± 0.471
1.717ValAsp: 1.717 ± 1.024
2.575ValGlu: 2.575 ± 0.915
1.431ValPhe: 1.431 ± 0.576
2.575ValGly: 2.575 ± 0.313
1.431ValHis: 1.431 ± 0.3
5.436ValIle: 5.436 ± 1.221
3.433ValLys: 3.433 ± 0.836
5.722ValLeu: 5.722 ± 0.954
0.572ValMet: 0.572 ± 0.325
3.72ValAsn: 3.72 ± 0.34
3.433ValPro: 3.433 ± 0.916
2.861ValGln: 2.861 ± 0.883
1.717ValArg: 1.717 ± 0.691
4.292ValSer: 4.292 ± 0.881
4.864ValThr: 4.864 ± 1.149
4.578ValVal: 4.578 ± 0.912
1.144ValTrp: 1.144 ± 0.258
2.575ValTyr: 2.575 ± 0.483
0.0ValXaa: 0.0 ± 0.0
Trp
0.858TrpAla: 0.858 ± 0.4
0.286TrpCys: 0.286 ± 0.362
1.144TrpAsp: 1.144 ± 0.636
2.003TrpGlu: 2.003 ± 0.927
0.286TrpPhe: 0.286 ± 0.29
0.572TrpGly: 0.572 ± 0.58
0.572TrpHis: 0.572 ± 0.36
1.144TrpIle: 1.144 ± 0.369
1.144TrpLys: 1.144 ± 0.362
2.575TrpLeu: 2.575 ± 0.751
0.286TrpMet: 0.286 ± 0.215
1.144TrpAsn: 1.144 ± 0.694
1.144TrpPro: 1.144 ± 0.392
2.289TrpGln: 2.289 ± 0.517
1.431TrpArg: 1.431 ± 0.587
0.572TrpSer: 0.572 ± 0.43
0.858TrpThr: 0.858 ± 0.383
0.858TrpVal: 0.858 ± 0.776
0.572TrpTrp: 0.572 ± 0.275
0.572TrpTyr: 0.572 ± 0.234
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.431TyrAla: 1.431 ± 0.899
0.572TyrCys: 0.572 ± 0.36
2.861TyrAsp: 2.861 ± 1.199
2.861TyrGlu: 2.861 ± 1.267
0.572TyrPhe: 0.572 ± 0.515
2.289TyrGly: 2.289 ± 1.8
0.286TyrHis: 0.286 ± 0.215
2.575TyrIle: 2.575 ± 1.005
2.289TyrLys: 2.289 ± 0.53
3.147TyrLeu: 3.147 ± 1.684
0.0TyrMet: 0.0 ± 0.0
2.575TyrAsn: 2.575 ± 0.947
2.575TyrPro: 2.575 ± 0.653
1.431TyrGln: 1.431 ± 0.3
0.858TyrArg: 0.858 ± 0.471
2.289TyrSer: 2.289 ± 0.893
2.003TyrThr: 2.003 ± 0.72
4.006TyrVal: 4.006 ± 1.036
1.144TyrTrp: 1.144 ± 0.637
2.575TyrTyr: 2.575 ± 1.158
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 5 proteins (3496 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski