Amino acid dipepetide frequency for Desulfotignum phosphitoxidans DSM 13687

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	8.916AlaAla: 8.916 ± 0.109	1.359AlaCys: 1.359 ± 0.038	5.08AlaAsp: 5.08 ± 0.062	4.116AlaGlu: 4.116 ± 0.06	3.804AlaPhe: 3.804 ± 0.047	7.695AlaGly: 7.695 ± 0.088	1.812AlaHis: 1.812 ± 0.035	4.84AlaIle: 4.84 ± 0.069	3.918AlaLys: 3.918 ± 0.062	8.599AlaLeu: 8.599 ± 0.084	2.855AlaMet: 2.855 ± 0.046	2.147AlaAsn: 2.147 ± 0.039	2.898AlaPro: 2.898 ± 0.054	2.896AlaGln: 2.896 ± 0.046	5.225AlaArg: 5.225 ± 0.062	4.057AlaSer: 4.057 ± 0.06	3.541AlaThr: 3.541 ± 0.055	6.988AlaVal: 6.988 ± 0.081	1.019AlaTrp: 1.019 ± 0.028	2.232AlaTyr: 2.232 ± 0.041	0.0AlaXaa: 0.0 ± 0.0
Cys	1.074CysAla: 1.074 ± 0.029	0.251CysCys: 0.251 ± 0.015	0.787CysAsp: 0.787 ± 0.022	0.633CysGlu: 0.633 ± 0.019	0.655CysPhe: 0.655 ± 0.02	1.262CysGly: 1.262 ± 0.036	0.518CysHis: 0.518 ± 0.027	0.808CysIle: 0.808 ± 0.025	0.565CysLys: 0.565 ± 0.018	1.394CysLeu: 1.394 ± 0.03	0.353CysMet: 0.353 ± 0.015	0.437CysAsn: 0.437 ± 0.018	0.839CysPro: 0.839 ± 0.035	0.394CysGln: 0.394 ± 0.017	0.958CysArg: 0.958 ± 0.026	0.734CysSer: 0.734 ± 0.025	0.696CysThr: 0.696 ± 0.026	0.86CysVal: 0.86 ± 0.026	0.128CysTrp: 0.128 ± 0.009	0.324CysTyr: 0.324 ± 0.015	0.0CysXaa: 0.0 ± 0.0
Asp	4.548AspAla: 4.548 ± 0.055	0.661AspCys: 0.661 ± 0.024	3.007AspAsp: 3.007 ± 0.048	3.238AspGlu: 3.238 ± 0.047	2.75AspPhe: 2.75 ± 0.045	3.373AspGly: 3.373 ± 0.056	1.571AspHis: 1.571 ± 0.032	4.859AspIle: 4.859 ± 0.061	2.948AspLys: 2.948 ± 0.043	6.769AspLeu: 6.769 ± 0.085	1.85AspMet: 1.85 ± 0.037	1.955AspAsn: 1.955 ± 0.038	3.662AspPro: 3.662 ± 0.059	2.42AspGln: 2.42 ± 0.044	3.667AspArg: 3.667 ± 0.051	2.551AspSer: 2.551 ± 0.046	3.692AspThr: 3.692 ± 0.056	3.589AspVal: 3.589 ± 0.053	0.71AspTrp: 0.71 ± 0.025	1.771AspTyr: 1.771 ± 0.035	0.0AspXaa: 0.0 ± 0.0
Glu	4.297GluAla: 4.297 ± 0.062	0.537GluCys: 0.537 ± 0.021	3.002GluAsp: 3.002 ± 0.044	3.171GluGlu: 3.171 ± 0.051	2.132GluPhe: 2.132 ± 0.038	2.784GluGly: 2.784 ± 0.047	1.106GluHis: 1.106 ± 0.033	4.563GluIle: 4.563 ± 0.066	5.719GluLys: 5.719 ± 0.067	4.831GluLeu: 4.831 ± 0.059	1.772GluMet: 1.772 ± 0.036	3.07GluAsn: 3.07 ± 0.054	2.071GluPro: 2.071 ± 0.041	2.439GluGln: 2.439 ± 0.046	2.675GluArg: 2.675 ± 0.047	2.95GluSer: 2.95 ± 0.04	4.011GluThr: 4.011 ± 0.055	3.1GluVal: 3.1 ± 0.056	0.62GluTrp: 0.62 ± 0.021	1.626GluTyr: 1.626 ± 0.034	0.0GluXaa: 0.0 ± 0.0
Phe	3.359PheAla: 3.359 ± 0.055	0.743PheCys: 0.743 ± 0.024	3.03PheAsp: 3.03 ± 0.045	2.525PheGlu: 2.525 ± 0.045	2.666PhePhe: 2.666 ± 0.052	3.079PheGly: 3.079 ± 0.059	1.122PheHis: 1.122 ± 0.029	2.871PheIle: 2.871 ± 0.05	2.311PheLys: 2.311 ± 0.041	4.609PheLeu: 4.609 ± 0.061	1.296PheMet: 1.296 ± 0.033	1.756PheAsn: 1.756 ± 0.03	1.925PhePro: 1.925 ± 0.037	1.572PheGln: 1.572 ± 0.036	2.051PheArg: 2.051 ± 0.04	3.443PheSer: 3.443 ± 0.052	2.392PheThr: 2.392 ± 0.043	2.935PheVal: 2.935 ± 0.05	0.57PheTrp: 0.57 ± 0.021	1.449PheTyr: 1.449 ± 0.031	0.0PheXaa: 0.0 ± 0.0
Gly	5.361GlyAla: 5.361 ± 0.083	1.173GlyCys: 1.173 ± 0.034	3.342GlyAsp: 3.342 ± 0.055	3.472GlyGlu: 3.472 ± 0.053	3.784GlyPhe: 3.784 ± 0.056	4.846GlyGly: 4.846 ± 0.071	1.692GlyHis: 1.692 ± 0.036	6.09GlyIle: 6.09 ± 0.064	4.432GlyLys: 4.432 ± 0.063	7.063GlyLeu: 7.063 ± 0.077	2.552GlyMet: 2.552 ± 0.052	2.454GlyAsn: 2.454 ± 0.041	2.537GlyPro: 2.537 ± 0.046	2.496GlyGln: 2.496 ± 0.043	4.049GlyArg: 4.049 ± 0.064	3.965GlySer: 3.965 ± 0.06	4.235GlyThr: 4.235 ± 0.057	4.958GlyVal: 4.958 ± 0.069	0.937GlyTrp: 0.937 ± 0.029	2.568GlyTyr: 2.568 ± 0.053	0.0GlyXaa: 0.0 ± 0.0
His	1.801HisAla: 1.801 ± 0.039	0.382HisCys: 0.382 ± 0.016	1.341HisAsp: 1.341 ± 0.029	1.194HisGlu: 1.194 ± 0.027	1.053HisPhe: 1.053 ± 0.028	1.682HisGly: 1.682 ± 0.039	0.681HisHis: 0.681 ± 0.026	1.597HisIle: 1.597 ± 0.032	1.019HisLys: 1.019 ± 0.025	2.587HisLeu: 2.587 ± 0.04	0.677HisMet: 0.677 ± 0.023	0.718HisAsn: 0.718 ± 0.024	1.557HisPro: 1.557 ± 0.032	0.941HisGln: 0.941 ± 0.025	1.333HisArg: 1.333 ± 0.034	1.117HisSer: 1.117 ± 0.029	1.353HisThr: 1.353 ± 0.029	1.506HisVal: 1.506 ± 0.034	0.249HisTrp: 0.249 ± 0.014	0.697HisTyr: 0.697 ± 0.026	0.0HisXaa: 0.0 ± 0.0
Ile	5.321IleAla: 5.321 ± 0.06	1.061IleCys: 1.061 ± 0.027	4.102IleAsp: 4.102 ± 0.059	3.894IleGlu: 3.894 ± 0.053	2.999IlePhe: 2.999 ± 0.051	4.511IleGly: 4.511 ± 0.055	1.989IleHis: 1.989 ± 0.038	4.491IleIle: 4.491 ± 0.069	3.716IleLys: 3.716 ± 0.055	6.851IleLeu: 6.851 ± 0.07	1.747IleMet: 1.747 ± 0.035	2.553IleAsn: 2.553 ± 0.041	3.664IlePro: 3.664 ± 0.055	3.052IleGln: 3.052 ± 0.049	4.325IleArg: 4.325 ± 0.054	4.454IleSer: 4.454 ± 0.054	4.089IleThr: 4.089 ± 0.055	4.094IleVal: 4.094 ± 0.061	0.66IleTrp: 0.66 ± 0.026	1.801IleTyr: 1.801 ± 0.037	0.0IleXaa: 0.0 ± 0.0
Lys	4.498LysAla: 4.498 ± 0.06	0.491LysCys: 0.491 ± 0.022	3.592LysAsp: 3.592 ± 0.059	3.957LysGlu: 3.957 ± 0.055	1.656LysPhe: 1.656 ± 0.04	4.077LysGly: 4.077 ± 0.05	1.077LysHis: 1.077 ± 0.027	4.51LysIle: 4.51 ± 0.072	5.182LysLys: 5.182 ± 0.072	4.146LysLeu: 4.146 ± 0.061	1.753LysMet: 1.753 ± 0.039	2.957LysAsn: 2.957 ± 0.047	2.312LysPro: 2.312 ± 0.042	2.654LysGln: 2.654 ± 0.043	2.578LysArg: 2.578 ± 0.044	2.915LysSer: 2.915 ± 0.046	4.056LysThr: 4.056 ± 0.056	2.889LysVal: 2.889 ± 0.046	0.555LysTrp: 0.555 ± 0.019	1.552LysTyr: 1.552 ± 0.036	0.0LysXaa: 0.0 ± 0.0
Leu	9.241LeuAla: 9.241 ± 0.092	1.355LeuCys: 1.355 ± 0.031	5.94LeuAsp: 5.94 ± 0.073	6.11LeuGlu: 6.11 ± 0.068	4.602LeuPhe: 4.602 ± 0.061	6.764LeuGly: 6.764 ± 0.077	1.816LeuHis: 1.816 ± 0.034	6.088LeuIle: 6.088 ± 0.075	6.092LeuLys: 6.092 ± 0.061	8.604LeuLeu: 8.604 ± 0.098	2.739LeuMet: 2.739 ± 0.041	3.689LeuAsn: 3.689 ± 0.057	4.729LeuPro: 4.729 ± 0.058	2.632LeuGln: 2.632 ± 0.045	3.895LeuArg: 3.895 ± 0.06	6.59LeuSer: 6.59 ± 0.065	5.949LeuThr: 5.949 ± 0.065	6.668LeuVal: 6.668 ± 0.079	0.938LeuTrp: 0.938 ± 0.028	2.516LeuTyr: 2.516 ± 0.043	0.0LeuXaa: 0.0 ± 0.0
Met	3.277MetAla: 3.277 ± 0.051	0.252MetCys: 0.252 ± 0.013	2.237MetAsp: 2.237 ± 0.038	1.935MetGlu: 1.935 ± 0.041	0.902MetPhe: 0.902 ± 0.024	2.343MetGly: 2.343 ± 0.046	0.527MetHis: 0.527 ± 0.019	2.068MetIle: 2.068 ± 0.041	1.861MetLys: 1.861 ± 0.038	2.419MetLeu: 2.419 ± 0.045	0.813MetMet: 0.813 ± 0.026	1.174MetAsn: 1.174 ± 0.03	1.431MetPro: 1.431 ± 0.029	0.88MetGln: 0.88 ± 0.024	1.091MetArg: 1.091 ± 0.026	1.401MetSer: 1.401 ± 0.033	2.126MetThr: 2.126 ± 0.034	2.228MetVal: 2.228 ± 0.041	0.206MetTrp: 0.206 ± 0.012	0.546MetTyr: 0.546 ± 0.017	0.0MetXaa: 0.0 ± 0.0
Asn	2.86AsnAla: 2.86 ± 0.046	0.486AsnCys: 0.486 ± 0.019	1.874AsnAsp: 1.874 ± 0.033	1.794AsnGlu: 1.794 ± 0.04	1.417AsnPhe: 1.417 ± 0.037	2.364AsnGly: 2.364 ± 0.042	0.924AsnHis: 0.924 ± 0.029	2.691AsnIle: 2.691 ± 0.05	1.726AsnLys: 1.726 ± 0.037	3.693AsnLeu: 3.693 ± 0.066	0.98AsnMet: 0.98 ± 0.025	1.3AsnAsn: 1.3 ± 0.034	2.258AsnPro: 2.258 ± 0.039	1.735AsnGln: 1.735 ± 0.035	2.397AsnArg: 2.397 ± 0.041	1.529AsnSer: 1.529 ± 0.031	2.01AsnThr: 2.01 ± 0.038	2.061AsnVal: 2.061 ± 0.039	0.407AsnTrp: 0.407 ± 0.015	0.993AsnTyr: 0.993 ± 0.025	0.0AsnXaa: 0.0 ± 0.0
Pro	4.093ProAla: 4.093 ± 0.055	0.589ProCys: 0.589 ± 0.02	4.254ProAsp: 4.254 ± 0.067	3.872ProGlu: 3.872 ± 0.057	2.228ProPhe: 2.228 ± 0.041	4.22ProGly: 4.22 ± 0.067	1.014ProHis: 1.014 ± 0.026	2.079ProIle: 2.079 ± 0.041	2.053ProLys: 2.053 ± 0.036	4.135ProLeu: 4.135 ± 0.058	1.268ProMet: 1.268 ± 0.027	1.12ProAsn: 1.12 ± 0.028	1.786ProPro: 1.786 ± 0.043	1.239ProGln: 1.239 ± 0.029	2.007ProArg: 2.007 ± 0.038	2.23ProSer: 2.23 ± 0.041	1.664ProThr: 1.664 ± 0.037	4.523ProVal: 4.523 ± 0.061	0.583ProTrp: 0.583 ± 0.021	1.282ProTyr: 1.282 ± 0.033	0.0ProXaa: 0.0 ± 0.0
Gln	3.753GlnAla: 3.753 ± 0.056	0.407GlnCys: 0.407 ± 0.019	1.929GlnAsp: 1.929 ± 0.034	2.081GlnGlu: 2.081 ± 0.031	1.39GlnPhe: 1.39 ± 0.03	2.7GlnGly: 2.7 ± 0.046	0.723GlnHis: 0.723 ± 0.026	2.991GlnIle: 2.991 ± 0.046	2.542GlnLys: 2.542 ± 0.039	2.977GlnLeu: 2.977 ± 0.05	1.283GlnMet: 1.283 ± 0.032	1.406GlnAsn: 1.406 ± 0.028	1.315GlnPro: 1.315 ± 0.032	1.358GlnGln: 1.358 ± 0.033	1.704GlnArg: 1.704 ± 0.038	1.778GlnSer: 1.778 ± 0.038	2.51GlnThr: 2.51 ± 0.041	2.942GlnVal: 2.942 ± 0.051	0.444GlnTrp: 0.444 ± 0.017	1.023GlnTyr: 1.023 ± 0.029	0.0GlnXaa: 0.0 ± 0.0
Arg	3.645ArgAla: 3.645 ± 0.051	0.694ArgCys: 0.694 ± 0.025	2.815ArgAsp: 2.815 ± 0.05	3.16ArgGlu: 3.16 ± 0.055	3.031ArgPhe: 3.031 ± 0.044	2.643ArgGly: 2.643 ± 0.047	1.489ArgHis: 1.489 ± 0.036	4.436ArgIle: 4.436 ± 0.058	3.314ArgLys: 3.314 ± 0.049	5.665ArgLeu: 5.665 ± 0.068	1.643ArgMet: 1.643 ± 0.032	1.935ArgAsn: 1.935 ± 0.036	2.32ArgPro: 2.32 ± 0.042	2.697ArgGln: 2.697 ± 0.045	2.792ArgArg: 2.792 ± 0.042	2.749ArgSer: 2.749 ± 0.042	2.737ArgThr: 2.737 ± 0.047	3.626ArgVal: 3.626 ± 0.053	0.561ArgTrp: 0.561 ± 0.02	1.794ArgTyr: 1.794 ± 0.036	0.0ArgXaa: 0.0 ± 0.0
Ser	4.36SerAla: 4.36 ± 0.05	0.732SerCys: 0.732 ± 0.022	3.35SerAsp: 3.35 ± 0.053	2.951SerGlu: 2.951 ± 0.045	2.653SerPhe: 2.653 ± 0.045	5.123SerGly: 5.123 ± 0.064	1.367SerHis: 1.367 ± 0.029	3.363SerIle: 3.363 ± 0.049	2.392SerLys: 2.392 ± 0.045	5.637SerLeu: 5.637 ± 0.059	1.632SerMet: 1.632 ± 0.032	1.559SerAsn: 1.559 ± 0.036	2.639SerPro: 2.639 ± 0.039	1.863SerGln: 1.863 ± 0.036	3.677SerArg: 3.677 ± 0.056	3.018SerSer: 3.018 ± 0.052	2.48SerThr: 2.48 ± 0.044	3.765SerVal: 3.765 ± 0.056	0.678SerTrp: 0.678 ± 0.024	1.467SerTyr: 1.467 ± 0.036	0.0SerXaa: 0.0 ± 0.0
Thr	5.163ThrAla: 5.163 ± 0.07	0.809ThrCys: 0.809 ± 0.026	3.513ThrAsp: 3.513 ± 0.046	2.523ThrGlu: 2.523 ± 0.041	2.26ThrPhe: 2.26 ± 0.042	5.765ThrGly: 5.765 ± 0.066	1.489ThrHis: 1.489 ± 0.031	3.688ThrIle: 3.688 ± 0.055	2.032ThrLys: 2.032 ± 0.041	6.174ThrLeu: 6.174 ± 0.073	1.289ThrMet: 1.289 ± 0.031	1.457ThrAsn: 1.457 ± 0.031	3.19ThrPro: 3.19 ± 0.053	1.962ThrGln: 1.962 ± 0.041	3.82ThrArg: 3.82 ± 0.051	2.758ThrSer: 2.758 ± 0.042	2.739ThrThr: 2.739 ± 0.05	3.953ThrVal: 3.953 ± 0.051	0.64ThrTrp: 0.64 ± 0.022	1.485ThrTyr: 1.485 ± 0.034	0.0ThrXaa: 0.0 ± 0.0
Val	5.44ValAla: 5.44 ± 0.075	1.134ValCys: 1.134 ± 0.035	3.898ValAsp: 3.898 ± 0.055	3.613ValGlu: 3.613 ± 0.051	3.658ValPhe: 3.658 ± 0.049	3.938ValGly: 3.938 ± 0.056	1.473ValHis: 1.473 ± 0.028	4.79ValIle: 4.79 ± 0.052	3.672ValLys: 3.672 ± 0.053	6.726ValLeu: 6.726 ± 0.071	2.173ValMet: 2.173 ± 0.041	2.467ValAsn: 2.467 ± 0.04	3.203ValPro: 3.203 ± 0.051	2.2ValGln: 2.2 ± 0.038	3.364ValArg: 3.364 ± 0.045	4.427ValSer: 4.427 ± 0.055	4.361ValThr: 4.361 ± 0.065	4.924ValVal: 4.924 ± 0.07	0.708ValTrp: 0.708 ± 0.026	1.862ValTyr: 1.862 ± 0.037	0.0ValXaa: 0.0 ± 0.0
Trp	0.785TrpAla: 0.785 ± 0.025	0.14TrpCys: 0.14 ± 0.008	0.674TrpAsp: 0.674 ± 0.025	0.693TrpGlu: 0.693 ± 0.021	0.567TrpPhe: 0.567 ± 0.022	0.747TrpGly: 0.747 ± 0.024	0.325TrpHis: 0.325 ± 0.014	0.852TrpIle: 0.852 ± 0.026	0.596TrpLys: 0.596 ± 0.02	1.133TrpLeu: 1.133 ± 0.033	0.331TrpMet: 0.331 ± 0.014	0.375TrpAsn: 0.375 ± 0.018	0.474TrpPro: 0.474 ± 0.021	0.604TrpGln: 0.604 ± 0.021	0.498TrpArg: 0.498 ± 0.019	0.516TrpSer: 0.516 ± 0.02	0.54TrpThr: 0.54 ± 0.019	0.771TrpVal: 0.771 ± 0.025	0.154TrpTrp: 0.154 ± 0.013	0.343TrpTyr: 0.343 ± 0.015	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.207TyrAla: 2.207 ± 0.037	0.415TyrCys: 0.415 ± 0.016	1.822TyrAsp: 1.822 ± 0.036	1.544TyrGlu: 1.544 ± 0.034	1.495TyrPhe: 1.495 ± 0.035	2.089TyrGly: 2.089 ± 0.039	0.771TyrHis: 0.771 ± 0.025	1.699TyrIle: 1.699 ± 0.035	1.318TyrLys: 1.318 ± 0.034	2.946TyrLeu: 2.946 ± 0.049	0.709TyrMet: 0.709 ± 0.021	0.972TyrAsn: 0.972 ± 0.029	1.431TyrPro: 1.431 ± 0.034	1.224TyrGln: 1.224 ± 0.029	1.64TyrArg: 1.64 ± 0.034	1.523TyrSer: 1.523 ± 0.039	1.526TyrThr: 1.526 ± 0.033	1.65TyrVal: 1.65 ± 0.038	0.352TyrTrp: 0.352 ± 0.016	0.975TyrTyr: 0.975 ± 0.028	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4515 proteins (1467878 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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