Amino acid dipepetide frequency for Scyliorhinus torazame (Cloudy catshark)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	6.436AlaAla: 6.436 ± 0.085	1.206AlaCys: 1.206 ± 0.014	3.114AlaAsp: 3.114 ± 0.023	4.958AlaGlu: 4.958 ± 0.057	2.272AlaPhe: 2.272 ± 0.018	4.104AlaGly: 4.104 ± 0.037	1.37AlaHis: 1.37 ± 0.019	3.06AlaIle: 3.06 ± 0.022	3.527AlaLys: 3.527 ± 0.026	6.06AlaLeu: 6.06 ± 0.044	1.57AlaMet: 1.57 ± 0.025	2.377AlaAsn: 2.377 ± 0.019	2.821AlaPro: 2.821 ± 0.028	2.805AlaGln: 2.805 ± 0.029	3.144AlaArg: 3.144 ± 0.032	4.909AlaSer: 4.909 ± 0.034	3.486AlaThr: 3.486 ± 0.023	4.899AlaVal: 4.899 ± 0.043	0.653AlaTrp: 0.653 ± 0.012	1.423AlaTyr: 1.423 ± 0.017	0.0AlaXaa: 0.0 ± 0.0
Cys	1.18CysAla: 1.18 ± 0.015	0.611CysCys: 0.611 ± 0.011	1.21CysAsp: 1.21 ± 0.026	1.474CysGlu: 1.474 ± 0.029	0.827CysPhe: 0.827 ± 0.011	1.45CysGly: 1.45 ± 0.021	0.594CysHis: 0.594 ± 0.01	1.092CysIle: 1.092 ± 0.013	1.241CysLys: 1.241 ± 0.014	2.01CysLeu: 2.01 ± 0.02	0.441CysMet: 0.441 ± 0.007	0.962CysAsn: 0.962 ± 0.013	1.139CysPro: 1.139 ± 0.017	1.023CysGln: 1.023 ± 0.014	1.254CysArg: 1.254 ± 0.016	1.939CysSer: 1.939 ± 0.019	1.232CysThr: 1.232 ± 0.016	1.419CysVal: 1.419 ± 0.021	0.279CysTrp: 0.279 ± 0.006	0.609CysTyr: 0.609 ± 0.009	0.0CysXaa: 0.0 ± 0.0
Asp	3.035AspAla: 3.035 ± 0.03	1.214AspCys: 1.214 ± 0.017	3.248AspAsp: 3.248 ± 0.042	3.909AspGlu: 3.909 ± 0.036	2.029AspPhe: 2.029 ± 0.017	3.647AspGly: 3.647 ± 0.044	1.25AspHis: 1.25 ± 0.018	3.123AspIle: 3.123 ± 0.031	2.772AspLys: 2.772 ± 0.024	5.04AspLeu: 5.04 ± 0.034	1.222AspMet: 1.222 ± 0.016	2.165AspAsn: 2.165 ± 0.023	2.783AspPro: 2.783 ± 0.035	2.101AspGln: 2.101 ± 0.022	2.957AspArg: 2.957 ± 0.043	4.47AspSer: 4.47 ± 0.043	3.118AspThr: 3.118 ± 0.052	3.61AspVal: 3.61 ± 0.049	0.699AspTrp: 0.699 ± 0.01	1.657AspTyr: 1.657 ± 0.018	0.0AspXaa: 0.0 ± 0.0
Glu	4.531GluAla: 4.531 ± 0.036	1.413GluCys: 1.413 ± 0.02	4.495GluAsp: 4.495 ± 0.038	7.532GluGlu: 7.532 ± 0.075	2.172GluPhe: 2.172 ± 0.023	4.004GluGly: 4.004 ± 0.04	1.714GluHis: 1.714 ± 0.021	3.774GluIle: 3.774 ± 0.034	5.263GluLys: 5.263 ± 0.044	6.482GluLeu: 6.482 ± 0.052	2.005GluMet: 2.005 ± 0.022	3.464GluAsn: 3.464 ± 0.024	2.628GluPro: 2.628 ± 0.026	3.562GluGln: 3.562 ± 0.033	5.106GluArg: 5.106 ± 0.067	4.917GluSer: 4.917 ± 0.04	4.079GluThr: 4.079 ± 0.042	4.246GluVal: 4.246 ± 0.035	0.754GluTrp: 0.754 ± 0.011	1.869GluTyr: 1.869 ± 0.026	0.0GluXaa: 0.0 ± 0.0
Phe	2.02PheAla: 2.02 ± 0.017	0.872PheCys: 0.872 ± 0.011	1.886PheAsp: 1.886 ± 0.02	2.105PheGlu: 2.105 ± 0.02	1.396PhePhe: 1.396 ± 0.015	2.18PheGly: 2.18 ± 0.019	0.957PheHis: 0.957 ± 0.013	1.951PheIle: 1.951 ± 0.017	1.919PheLys: 1.919 ± 0.015	3.627PheLeu: 3.627 ± 0.031	0.761PheMet: 0.761 ± 0.014	1.557PheAsn: 1.557 ± 0.016	1.742PhePro: 1.742 ± 0.015	1.7PheGln: 1.7 ± 0.015	1.797PheArg: 1.797 ± 0.019	2.98PheSer: 2.98 ± 0.021	2.159PheThr: 2.159 ± 0.023	2.238PheVal: 2.238 ± 0.021	0.448PheTrp: 0.448 ± 0.007	1.146PheTyr: 1.146 ± 0.012	0.0PheXaa: 0.0 ± 0.0
Gly	3.7GlyAla: 3.7 ± 0.033	1.178GlyCys: 1.178 ± 0.014	3.284GlyAsp: 3.284 ± 0.044	4.136GlyGlu: 4.136 ± 0.041	2.283GlyPhe: 2.283 ± 0.022	3.991GlyGly: 3.991 ± 0.039	1.478GlyHis: 1.478 ± 0.018	3.245GlyIle: 3.245 ± 0.03	3.832GlyLys: 3.832 ± 0.025	5.169GlyLeu: 5.169 ± 0.045	1.442GlyMet: 1.442 ± 0.016	2.832GlyAsn: 2.832 ± 0.026	2.705GlyPro: 2.705 ± 0.049	2.655GlyGln: 2.655 ± 0.027	3.348GlyArg: 3.348 ± 0.028	5.124GlySer: 5.124 ± 0.031	3.567GlyThr: 3.567 ± 0.035	3.689GlyVal: 3.689 ± 0.043	0.717GlyTrp: 0.717 ± 0.011	1.804GlyTyr: 1.804 ± 0.021	0.0GlyXaa: 0.0 ± 0.0
His	1.303HisAla: 1.303 ± 0.021	0.758HisCys: 0.758 ± 0.012	0.996HisAsp: 0.996 ± 0.015	1.31HisGlu: 1.31 ± 0.016	1.042HisPhe: 1.042 ± 0.012	1.435HisGly: 1.435 ± 0.016	0.833HisHis: 0.833 ± 0.013	1.329HisIle: 1.329 ± 0.014	1.319HisLys: 1.319 ± 0.012	2.602HisLeu: 2.602 ± 0.024	0.568HisMet: 0.568 ± 0.011	1.007HisAsn: 1.007 ± 0.012	1.371HisPro: 1.371 ± 0.016	1.278HisGln: 1.278 ± 0.013	1.482HisArg: 1.482 ± 0.017	2.205HisSer: 2.205 ± 0.021	1.312HisThr: 1.312 ± 0.016	1.489HisVal: 1.489 ± 0.016	0.346HisTrp: 0.346 ± 0.006	0.834HisTyr: 0.834 ± 0.012	0.0HisXaa: 0.0 ± 0.0
Ile	3.057IleAla: 3.057 ± 0.03	1.219IleCys: 1.219 ± 0.013	2.71IleAsp: 2.71 ± 0.037	3.197IleGlu: 3.197 ± 0.032	1.988IlePhe: 1.988 ± 0.018	2.75IleGly: 2.75 ± 0.023	1.337IleHis: 1.337 ± 0.016	2.837IleIle: 2.837 ± 0.023	2.957IleLys: 2.957 ± 0.021	4.921IleLeu: 4.921 ± 0.032	1.128IleMet: 1.128 ± 0.014	2.335IleAsn: 2.335 ± 0.022	2.866IlePro: 2.866 ± 0.024	2.557IleGln: 2.557 ± 0.022	2.601IleArg: 2.601 ± 0.028	4.197IleSer: 4.197 ± 0.033	3.069IleThr: 3.069 ± 0.03	3.08IleVal: 3.08 ± 0.027	0.578IleTrp: 0.578 ± 0.01	1.498IleTyr: 1.498 ± 0.016	0.0IleXaa: 0.0 ± 0.0
Lys	3.749LysAla: 3.749 ± 0.023	1.214LysCys: 1.214 ± 0.015	3.378LysAsp: 3.378 ± 0.028	5.398LysGlu: 5.398 ± 0.043	1.759LysPhe: 1.759 ± 0.015	3.309LysGly: 3.309 ± 0.028	1.522LysHis: 1.522 ± 0.017	3.109LysIle: 3.109 ± 0.024	4.679LysLys: 4.679 ± 0.037	5.641LysLeu: 5.641 ± 0.033	1.653LysMet: 1.653 ± 0.015	2.64LysAsn: 2.64 ± 0.02	2.809LysPro: 2.809 ± 0.024	2.936LysGln: 2.936 ± 0.025	3.558LysArg: 3.558 ± 0.023	4.175LysSer: 4.175 ± 0.03	3.302LysThr: 3.302 ± 0.023	3.727LysVal: 3.727 ± 0.027	0.648LysTrp: 0.648 ± 0.009	1.714LysTyr: 1.714 ± 0.018	0.0LysXaa: 0.0 ± 0.0
Leu	5.836LeuAla: 5.836 ± 0.04	2.095LeuCys: 2.095 ± 0.027	4.987LeuAsp: 4.987 ± 0.044	6.631LeuGlu: 6.631 ± 0.042	3.255LeuPhe: 3.255 ± 0.025	5.051LeuGly: 5.051 ± 0.039	2.619LeuHis: 2.619 ± 0.022	4.365LeuIle: 4.365 ± 0.042	6.048LeuLys: 6.048 ± 0.034	9.627LeuLeu: 9.627 ± 0.078	2.153LeuMet: 2.153 ± 0.021	4.103LeuAsn: 4.103 ± 0.03	4.801LeuPro: 4.801 ± 0.031	5.456LeuGln: 5.456 ± 0.041	5.07LeuArg: 5.07 ± 0.038	7.422LeuSer: 7.422 ± 0.041	5.273LeuThr: 5.273 ± 0.046	5.33LeuVal: 5.33 ± 0.044	0.989LeuTrp: 0.989 ± 0.014	2.648LeuTyr: 2.648 ± 0.031	0.0LeuXaa: 0.0 ± 0.0
Met	1.767MetAla: 1.767 ± 0.016	0.486MetCys: 0.486 ± 0.01	1.493MetAsp: 1.493 ± 0.022	2.05MetGlu: 2.05 ± 0.019	0.832MetPhe: 0.832 ± 0.01	1.346MetGly: 1.346 ± 0.021	0.52MetHis: 0.52 ± 0.009	1.043MetIle: 1.043 ± 0.012	1.653MetLys: 1.653 ± 0.013	2.095MetLeu: 2.095 ± 0.02	0.691MetMet: 0.691 ± 0.011	1.049MetAsn: 1.049 ± 0.013	1.052MetPro: 1.052 ± 0.016	1.061MetGln: 1.061 ± 0.011	1.145MetArg: 1.145 ± 0.017	1.728MetSer: 1.728 ± 0.018	1.251MetThr: 1.251 ± 0.018	1.548MetVal: 1.548 ± 0.021	0.257MetTrp: 0.257 ± 0.005	0.681MetTyr: 0.681 ± 0.018	0.0MetXaa: 0.0 ± 0.0
Asn	2.515AsnAla: 2.515 ± 0.024	1.034AsnCys: 1.034 ± 0.014	2.048AsnAsp: 2.048 ± 0.021	2.864AsnGlu: 2.864 ± 0.027	1.538AsnPhe: 1.538 ± 0.014	2.953AsnGly: 2.953 ± 0.028	1.015AsnHis: 1.015 ± 0.012	2.589AsnIle: 2.589 ± 0.016	2.624AsnLys: 2.624 ± 0.022	4.155AsnLeu: 4.155 ± 0.028	1.085AsnMet: 1.085 ± 0.013	2.016AsnAsn: 2.016 ± 0.023	2.315AsnPro: 2.315 ± 0.025	1.926AsnGln: 1.926 ± 0.018	2.154AsnArg: 2.154 ± 0.016	3.55AsnSer: 3.55 ± 0.023	2.485AsnThr: 2.485 ± 0.025	2.795AsnVal: 2.795 ± 0.025	0.508AsnTrp: 0.508 ± 0.008	1.305AsnTyr: 1.305 ± 0.012	0.0AsnXaa: 0.0 ± 0.0
Pro	3.456ProAla: 3.456 ± 0.03	0.954ProCys: 0.954 ± 0.012	2.739ProAsp: 2.739 ± 0.031	3.769ProGlu: 3.769 ± 0.035	1.696ProPhe: 1.696 ± 0.013	3.707ProGly: 3.707 ± 0.063	1.191ProHis: 1.191 ± 0.015	2.094ProIle: 2.094 ± 0.02	2.523ProLys: 2.523 ± 0.023	4.265ProLeu: 4.265 ± 0.034	0.951ProMet: 0.951 ± 0.011	1.982ProAsn: 1.982 ± 0.021	3.678ProPro: 3.678 ± 0.045	2.16ProGln: 2.16 ± 0.02	2.457ProArg: 2.457 ± 0.019	4.394ProSer: 4.394 ± 0.035	2.686ProThr: 2.686 ± 0.025	3.558ProVal: 3.558 ± 0.031	0.501ProTrp: 0.501 ± 0.008	1.257ProTyr: 1.257 ± 0.015	0.0ProXaa: 0.0 ± 0.0
Gln	2.943GlnAla: 2.943 ± 0.026	1.056GlnCys: 1.056 ± 0.023	2.422GlnAsp: 2.422 ± 0.035	3.605GlnGlu: 3.605 ± 0.031	1.471GlnPhe: 1.471 ± 0.016	2.493GlnGly: 2.493 ± 0.026	1.315GlnHis: 1.315 ± 0.016	2.348GlnIle: 2.348 ± 0.019	2.962GlnLys: 2.962 ± 0.023	4.637GlnLeu: 4.637 ± 0.034	1.198GlnMet: 1.198 ± 0.012	2.178GlnAsn: 2.178 ± 0.017	2.227GlnPro: 2.227 ± 0.021	3.239GlnGln: 3.239 ± 0.037	3.046GlnArg: 3.046 ± 0.034	3.53GlnSer: 3.53 ± 0.028	2.586GlnThr: 2.586 ± 0.022	2.647GlnVal: 2.647 ± 0.021	0.542GlnTrp: 0.542 ± 0.009	1.363GlnTyr: 1.363 ± 0.018	0.0GlnXaa: 0.0 ± 0.0
Arg	3.561ArgAla: 3.561 ± 0.045	1.13ArgCys: 1.13 ± 0.015	3.014ArgAsp: 3.014 ± 0.035	4.469ArgGlu: 4.469 ± 0.057	1.86ArgPhe: 1.86 ± 0.017	3.03ArgGly: 3.03 ± 0.033	1.436ArgHis: 1.436 ± 0.018	2.689ArgIle: 2.689 ± 0.027	3.846ArgLys: 3.846 ± 0.024	4.881ArgLeu: 4.881 ± 0.036	1.322ArgMet: 1.322 ± 0.014	2.504ArgAsn: 2.504 ± 0.021	2.419ArgPro: 2.419 ± 0.024	2.651ArgGln: 2.651 ± 0.027	3.744ArgArg: 3.744 ± 0.035	4.171ArgSer: 4.171 ± 0.041	2.813ArgThr: 2.813 ± 0.029	3.066ArgVal: 3.066 ± 0.031	0.632ArgTrp: 0.632 ± 0.009	1.536ArgTyr: 1.536 ± 0.016	0.0ArgXaa: 0.0 ± 0.0
Ser	5.041SerAla: 5.041 ± 0.034	1.79SerCys: 1.79 ± 0.022	4.427SerAsp: 4.427 ± 0.037	5.589SerGlu: 5.589 ± 0.05	2.828SerPhe: 2.828 ± 0.022	5.211SerGly: 5.211 ± 0.04	1.891SerHis: 1.891 ± 0.017	3.704SerIle: 3.704 ± 0.022	4.434SerLys: 4.434 ± 0.027	7.411SerLeu: 7.411 ± 0.042	1.729SerMet: 1.729 ± 0.017	3.401SerAsn: 3.401 ± 0.026	4.657SerPro: 4.657 ± 0.044	3.585SerGln: 3.585 ± 0.025	4.104SerArg: 4.104 ± 0.03	8.132SerSer: 8.132 ± 0.062	4.653SerThr: 4.653 ± 0.037	5.17SerVal: 5.17 ± 0.034	0.897SerTrp: 0.897 ± 0.011	2.002SerTyr: 2.002 ± 0.019	0.0SerXaa: 0.0 ± 0.0
Thr	3.972ThrAla: 3.972 ± 0.033	1.29ThrCys: 1.29 ± 0.021	3.166ThrAsp: 3.166 ± 0.033	4.419ThrGlu: 4.419 ± 0.039	2.129ThrPhe: 2.129 ± 0.018	3.838ThrGly: 3.838 ± 0.041	1.198ThrHis: 1.198 ± 0.015	2.91ThrIle: 2.91 ± 0.025	2.955ThrLys: 2.955 ± 0.026	5.305ThrLeu: 5.305 ± 0.039	1.3ThrMet: 1.3 ± 0.016	2.2ThrAsn: 2.2 ± 0.018	3.048ThrPro: 3.048 ± 0.03	2.34ThrGln: 2.34 ± 0.036	2.447ThrArg: 2.447 ± 0.023	4.617ThrSer: 4.617 ± 0.031	3.185ThrThr: 3.185 ± 0.032	4.41ThrVal: 4.41 ± 0.046	0.658ThrTrp: 0.658 ± 0.013	1.417ThrTyr: 1.417 ± 0.014	0.0ThrXaa: 0.0 ± 0.0
Val	4.023ValAla: 4.023 ± 0.035	1.489ValCys: 1.489 ± 0.02	3.352ValAsp: 3.352 ± 0.038	4.202ValGlu: 4.202 ± 0.035	2.378ValPhe: 2.378 ± 0.029	3.484ValGly: 3.484 ± 0.04	1.543ValHis: 1.543 ± 0.017	3.38ValIle: 3.38 ± 0.038	3.963ValLys: 3.963 ± 0.031	6.013ValLeu: 6.013 ± 0.049	1.556ValMet: 1.556 ± 0.024	2.799ValAsn: 2.799 ± 0.026	3.22ValPro: 3.22 ± 0.03	3.007ValGln: 3.007 ± 0.028	3.047ValArg: 3.047 ± 0.024	4.985ValSer: 4.985 ± 0.043	4.191ValThr: 4.191 ± 0.042	4.048ValVal: 4.048 ± 0.038	0.709ValTrp: 0.709 ± 0.011	1.776ValTyr: 1.776 ± 0.024	0.0ValXaa: 0.0 ± 0.0
Trp	0.656TrpAla: 0.656 ± 0.011	0.245TrpCys: 0.245 ± 0.005	0.654TrpAsp: 0.654 ± 0.014	0.751TrpGlu: 0.751 ± 0.01	0.441TrpPhe: 0.441 ± 0.008	0.58TrpGly: 0.58 ± 0.01	0.274TrpHis: 0.274 ± 0.005	0.663TrpIle: 0.663 ± 0.011	0.843TrpLys: 0.843 ± 0.01	1.095TrpLeu: 1.095 ± 0.014	0.32TrpMet: 0.32 ± 0.007	0.61TrpAsn: 0.61 ± 0.008	0.394TrpPro: 0.394 ± 0.007	0.491TrpGln: 0.491 ± 0.007	0.676TrpArg: 0.676 ± 0.011	0.871TrpSer: 0.871 ± 0.014	0.663TrpThr: 0.663 ± 0.011	0.625TrpVal: 0.625 ± 0.009	0.179TrpTrp: 0.179 ± 0.005	0.35TrpTyr: 0.35 ± 0.007	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.415TyrAla: 1.415 ± 0.024	0.733TyrCys: 0.733 ± 0.01	1.424TyrAsp: 1.424 ± 0.025	1.643TyrGlu: 1.643 ± 0.02	1.246TyrPhe: 1.246 ± 0.013	1.616TyrGly: 1.616 ± 0.02	0.763TyrHis: 0.763 ± 0.012	1.575TyrIle: 1.575 ± 0.018	1.561TyrLys: 1.561 ± 0.015	2.727TyrLeu: 2.727 ± 0.025	0.653TyrMet: 0.653 ± 0.01	1.292TyrAsn: 1.292 ± 0.014	1.343TyrPro: 1.343 ± 0.024	1.274TyrGln: 1.274 ± 0.013	1.634TyrArg: 1.634 ± 0.018	2.342TyrSer: 2.342 ± 0.023	1.693TyrThr: 1.693 ± 0.024	1.57TyrVal: 1.57 ± 0.018	0.385TyrTrp: 0.385 ± 0.008	1.047TyrTyr: 1.047 ± 0.015	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 27602 proteins (10337261 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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