Amino acid dipepetide frequency for Sunn-hemp mosaic virus (SHMV) (TMV strain cowpea)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.375AlaAla: 3.375 ± 0.772
3.375AlaCys: 3.375 ± 0.772
2.893AlaAsp: 2.893 ± 0.874
4.822AlaGlu: 4.822 ± 4.203
1.446AlaPhe: 1.446 ± 0.702
3.857AlaGly: 3.857 ± 1.871
0.482AlaHis: 0.482 ± 0.234
2.411AlaIle: 2.411 ± 0.94
4.339AlaLys: 4.339 ± 1.154
4.339AlaLeu: 4.339 ± 0.405
1.446AlaMet: 1.446 ± 0.724
2.411AlaAsn: 2.411 ± 0.546
2.411AlaPro: 2.411 ± 1.47
1.446AlaGln: 1.446 ± 0.702
2.411AlaArg: 2.411 ± 0.94
4.339AlaSer: 4.339 ± 1.778
3.375AlaThr: 3.375 ± 1.202
4.339AlaVal: 4.339 ± 0.405
0.964AlaTrp: 0.964 ± 0.468
1.929AlaTyr: 1.929 ± 2.258
0.0AlaXaa: 0.0 ± 0.0
Cys
0.964CysAla: 0.964 ± 0.819
0.482CysCys: 0.482 ± 0.234
0.964CysAsp: 0.964 ± 0.468
1.929CysGlu: 1.929 ± 0.935
0.964CysPhe: 0.964 ± 0.468
1.929CysGly: 1.929 ± 0.935
0.0CysHis: 0.0 ± 0.0
0.964CysIle: 0.964 ± 0.468
0.964CysLys: 0.964 ± 0.468
3.375CysLeu: 3.375 ± 0.772
0.0CysMet: 0.0 ± 0.0
1.929CysAsn: 1.929 ± 0.559
0.482CysPro: 0.482 ± 0.234
0.964CysGln: 0.964 ± 0.468
1.446CysArg: 1.446 ± 0.661
1.929CysSer: 1.929 ± 0.559
0.0CysThr: 0.0 ± 0.0
1.446CysVal: 1.446 ± 0.661
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
2.893AspAla: 2.893 ± 0.874
0.482AspCys: 0.482 ± 0.234
4.822AspAsp: 4.822 ± 0.427
3.857AspGlu: 3.857 ± 0.505
2.411AspPhe: 2.411 ± 1.169
2.893AspGly: 2.893 ± 1.322
2.411AspHis: 2.411 ± 1.169
4.339AspIle: 4.339 ± 2.105
4.339AspLys: 4.339 ± 1.154
5.786AspLeu: 5.786 ± 1.805
2.411AspMet: 2.411 ± 1.169
1.446AspAsn: 1.446 ± 0.702
2.411AspPro: 2.411 ± 0.94
2.411AspGln: 2.411 ± 1.169
1.929AspArg: 1.929 ± 0.935
3.375AspSer: 3.375 ± 3.455
4.339AspThr: 4.339 ± 1.17
8.197AspVal: 8.197 ± 3.059
0.964AspTrp: 0.964 ± 0.468
3.375AspTyr: 3.375 ± 1.081
0.0AspXaa: 0.0 ± 0.0
Glu
2.893GluAla: 2.893 ± 1.403
0.482GluCys: 0.482 ± 0.234
2.411GluAsp: 2.411 ± 0.546
2.893GluGlu: 2.893 ± 1.322
4.822GluPhe: 4.822 ± 1.365
2.893GluGly: 2.893 ± 0.626
1.929GluHis: 1.929 ± 0.935
3.375GluIle: 3.375 ± 2.797
6.268GluLys: 6.268 ± 2.029
4.339GluLeu: 4.339 ± 0.405
1.446GluMet: 1.446 ± 0.702
4.339GluAsn: 4.339 ± 2.395
2.411GluPro: 2.411 ± 1.088
1.929GluGln: 1.929 ± 2.258
1.446GluArg: 1.446 ± 0.702
2.893GluSer: 2.893 ± 0.874
1.446GluThr: 1.446 ± 0.702
3.375GluVal: 3.375 ± 1.635
0.482GluTrp: 0.482 ± 0.234
4.822GluTyr: 4.822 ± 1.092
0.0GluXaa: 0.0 ± 0.0
Phe
0.964PheAla: 0.964 ± 0.468
2.411PheCys: 2.411 ± 1.169
4.339PheAsp: 4.339 ± 1.08
4.339PheGlu: 4.339 ± 0.405
2.411PhePhe: 2.411 ± 1.169
1.929PheGly: 1.929 ± 0.935
0.964PheHis: 0.964 ± 0.468
1.446PheIle: 1.446 ± 0.702
3.857PheLys: 3.857 ± 0.954
4.822PheLeu: 4.822 ± 1.365
0.0PheMet: 0.0 ± 0.0
2.411PheAsn: 2.411 ± 1.088
1.929PhePro: 1.929 ± 0.951
2.893PheGln: 2.893 ± 0.874
4.339PheArg: 4.339 ± 2.105
3.375PheSer: 3.375 ± 1.202
3.375PheThr: 3.375 ± 1.635
3.857PheVal: 3.857 ± 0.505
0.0PheTrp: 0.0 ± 0.0
1.446PheTyr: 1.446 ± 0.702
0.0PheXaa: 0.0 ± 0.0
Gly
1.929GlyAla: 1.929 ± 0.935
1.446GlyCys: 1.446 ± 0.702
3.375GlyAsp: 3.375 ± 1.637
2.411GlyGlu: 2.411 ± 1.169
2.411GlyPhe: 2.411 ± 0.546
1.446GlyGly: 1.446 ± 0.702
0.964GlyHis: 0.964 ± 0.819
1.929GlyIle: 1.929 ± 0.559
4.822GlyLys: 4.822 ± 2.94
6.268GlyLeu: 6.268 ± 0.267
0.964GlyMet: 0.964 ± 0.468
1.929GlyAsn: 1.929 ± 0.935
1.446GlyPro: 1.446 ± 0.702
1.929GlyGln: 1.929 ± 0.559
3.375GlyArg: 3.375 ± 0.675
2.411GlySer: 2.411 ± 1.47
2.411GlyThr: 2.411 ± 1.088
3.857GlyVal: 3.857 ± 0.505
0.482GlyTrp: 0.482 ± 0.234
1.929GlyTyr: 1.929 ± 0.559
0.0GlyXaa: 0.0 ± 0.0
His
1.929HisAla: 1.929 ± 0.559
0.482HisCys: 0.482 ± 0.234
0.964HisAsp: 0.964 ± 0.468
0.482HisGlu: 0.482 ± 0.234
1.929HisPhe: 1.929 ± 0.935
1.446HisGly: 1.446 ± 0.702
0.0HisHis: 0.0 ± 0.0
1.929HisIle: 1.929 ± 0.935
0.0HisLys: 0.0 ± 0.0
2.411HisLeu: 2.411 ± 0.546
1.446HisMet: 1.446 ± 0.702
0.482HisAsn: 0.482 ± 1.274
0.482HisPro: 0.482 ± 0.234
0.0HisGln: 0.0 ± 0.0
0.482HisArg: 0.482 ± 0.234
1.929HisSer: 1.929 ± 0.935
0.964HisThr: 0.964 ± 0.468
1.929HisVal: 1.929 ± 0.935
0.0HisTrp: 0.0 ± 0.0
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
1.929IleAla: 1.929 ± 0.559
0.482IleCys: 0.482 ± 0.234
2.411IleAsp: 2.411 ± 0.546
4.339IleGlu: 4.339 ± 0.405
2.411IlePhe: 2.411 ± 1.169
2.411IleGly: 2.411 ± 1.169
0.482IleHis: 0.482 ± 1.274
2.893IleIle: 2.893 ± 0.626
3.375IleLys: 3.375 ± 1.081
6.268IleLeu: 6.268 ± 0.267
0.0IleMet: 0.0 ± 0.0
3.857IleAsn: 3.857 ± 1.215
4.339IlePro: 4.339 ± 1.876
0.964IleGln: 0.964 ± 0.468
1.929IleArg: 1.929 ± 0.935
8.679IleSer: 8.679 ± 2.34
1.929IleThr: 1.929 ± 0.559
3.375IleVal: 3.375 ± 0.772
0.482IleTrp: 0.482 ± 0.234
2.411IleTyr: 2.411 ± 0.94
0.0IleXaa: 0.0 ± 0.0
Lys
5.786LysAla: 5.786 ± 1.253
0.482LysCys: 0.482 ± 0.234
3.857LysAsp: 3.857 ± 1.119
3.857LysGlu: 3.857 ± 1.119
3.857LysPhe: 3.857 ± 1.119
2.893LysGly: 2.893 ± 2.457
0.964LysHis: 0.964 ± 0.819
2.893LysIle: 2.893 ± 0.626
5.304LysLys: 5.304 ± 1.754
5.786LysLeu: 5.786 ± 1.253
0.482LysMet: 0.482 ± 0.234
1.929LysAsn: 1.929 ± 0.559
2.893LysPro: 2.893 ± 0.626
0.964LysGln: 0.964 ± 0.468
5.786LysArg: 5.786 ± 1.678
4.822LysSer: 4.822 ± 0.938
3.375LysThr: 3.375 ± 1.637
4.339LysVal: 4.339 ± 2.105
0.964LysTrp: 0.964 ± 0.819
2.893LysTyr: 2.893 ± 1.403
0.482LysXaa: 0.482 ± 0.234
Leu
5.786LeuAla: 5.786 ± 1.253
0.482LeuCys: 0.482 ± 0.234
7.232LeuAsp: 7.232 ± 1.72
6.75LeuGlu: 6.75 ± 2.369
2.411LeuPhe: 2.411 ± 0.546
5.786LeuGly: 5.786 ± 2.644
2.893LeuHis: 2.893 ± 1.403
5.304LeuIle: 5.304 ± 1.51
6.268LeuLys: 6.268 ± 3.596
12.536LeuLeu: 12.536 ± 1.682
0.482LeuMet: 0.482 ± 0.234
4.822LeuAsn: 4.822 ± 1.555
5.786LeuPro: 5.786 ± 1.253
2.893LeuGln: 2.893 ± 0.985
5.786LeuArg: 5.786 ± 1.749
8.197LeuSer: 8.197 ± 1.901
4.822LeuThr: 4.822 ± 2.176
6.75LeuVal: 6.75 ± 1.335
0.482LeuTrp: 0.482 ± 0.234
2.411LeuTyr: 2.411 ± 1.169
0.0LeuXaa: 0.0 ± 0.0
Met
1.929MetAla: 1.929 ± 0.951
0.0MetCys: 0.0 ± 0.0
0.482MetAsp: 0.482 ± 0.234
0.964MetGlu: 0.964 ± 0.468
0.482MetPhe: 0.482 ± 0.234
0.0MetGly: 0.0 ± 0.0
0.0MetHis: 0.0 ± 0.0
1.446MetIle: 1.446 ± 0.702
1.446MetLys: 1.446 ± 0.661
1.446MetLeu: 1.446 ± 0.702
0.482MetMet: 0.482 ± 0.234
1.446MetAsn: 1.446 ± 0.702
0.964MetPro: 0.964 ± 0.468
1.446MetGln: 1.446 ± 0.702
0.482MetArg: 0.482 ± 0.234
1.929MetSer: 1.929 ± 0.559
1.446MetThr: 1.446 ± 1.82
0.964MetVal: 0.964 ± 0.468
0.482MetTrp: 0.482 ± 0.234
0.964MetTyr: 0.964 ± 0.468
0.0MetXaa: 0.0 ± 0.0
Asn
2.411AsnAla: 2.411 ± 2.136
1.446AsnCys: 1.446 ± 1.82
1.929AsnAsp: 1.929 ± 0.559
1.929AsnGlu: 1.929 ± 0.559
3.857AsnPhe: 3.857 ± 1.871
2.893AsnGly: 2.893 ± 0.874
0.964AsnHis: 0.964 ± 0.468
0.964AsnIle: 0.964 ± 0.468
3.375AsnLys: 3.375 ± 1.637
4.339AsnLeu: 4.339 ± 1.375
0.482AsnMet: 0.482 ± 0.234
2.411AsnAsn: 2.411 ± 0.94
1.929AsnPro: 1.929 ± 0.559
0.964AsnGln: 0.964 ± 0.468
3.857AsnArg: 3.857 ± 3.15
3.375AsnSer: 3.375 ± 1.955
2.411AsnThr: 2.411 ± 0.546
5.786AsnVal: 5.786 ± 0.481
0.482AsnTrp: 0.482 ± 0.234
2.411AsnTyr: 2.411 ± 0.94
0.0AsnXaa: 0.0 ± 0.0
Pro
4.822ProAla: 4.822 ± 1.633
0.0ProCys: 0.0 ± 0.0
4.339ProAsp: 4.339 ± 2.105
1.929ProGlu: 1.929 ± 0.559
2.411ProPhe: 2.411 ± 1.088
5.304ProGly: 5.304 ± 1.754
0.482ProHis: 0.482 ± 0.234
2.411ProIle: 2.411 ± 0.94
2.411ProLys: 2.411 ± 0.546
3.375ProLeu: 3.375 ± 0.772
0.482ProMet: 0.482 ± 0.234
0.964ProAsn: 0.964 ± 0.819
1.446ProPro: 1.446 ± 0.702
0.482ProGln: 0.482 ± 0.234
2.893ProArg: 2.893 ± 0.985
2.411ProSer: 2.411 ± 2.497
1.446ProThr: 1.446 ± 1.017
2.411ProVal: 2.411 ± 0.546
0.0ProTrp: 0.0 ± 0.0
0.964ProTyr: 0.964 ± 0.468
0.0ProXaa: 0.0 ± 0.0
Gln
0.0GlnAla: 0.0 ± 0.0
1.446GlnCys: 1.446 ± 0.702
0.964GlnAsp: 0.964 ± 0.468
1.929GlnGlu: 1.929 ± 0.559
1.446GlnPhe: 1.446 ± 1.82
2.411GlnGly: 2.411 ± 0.546
0.0GlnHis: 0.0 ± 0.0
2.893GlnIle: 2.893 ± 1.403
3.857GlnLys: 3.857 ± 1.871
3.857GlnLeu: 3.857 ± 3.15
0.482GlnMet: 0.482 ± 0.234
2.411GlnAsn: 2.411 ± 1.169
0.0GlnPro: 0.0 ± 0.0
0.0GlnGln: 0.0 ± 0.0
1.929GlnArg: 1.929 ± 0.935
2.411GlnSer: 2.411 ± 2.497
1.929GlnThr: 1.929 ± 0.951
1.446GlnVal: 1.446 ± 1.017
2.411GlnTrp: 2.411 ± 0.546
0.964GlnTyr: 0.964 ± 0.468
0.0GlnXaa: 0.0 ± 0.0
Arg
1.929ArgAla: 1.929 ± 0.559
0.964ArgCys: 0.964 ± 0.468
4.339ArgAsp: 4.339 ± 1.876
0.964ArgGlu: 0.964 ± 1.129
2.411ArgPhe: 2.411 ± 0.94
1.446ArgGly: 1.446 ± 0.702
2.411ArgHis: 2.411 ± 1.169
3.857ArgIle: 3.857 ± 1.871
4.339ArgLys: 4.339 ± 1.154
3.857ArgLeu: 3.857 ± 0.505
0.0ArgMet: 0.0 ± 0.0
3.857ArgAsn: 3.857 ± 1.215
1.446ArgPro: 1.446 ± 0.702
0.482ArgGln: 0.482 ± 0.234
2.893ArgArg: 2.893 ± 0.874
5.786ArgSer: 5.786 ± 2.897
6.75ArgThr: 6.75 ± 2.791
4.339ArgVal: 4.339 ± 1.17
0.0ArgTrp: 0.0 ± 0.0
2.411ArgTyr: 2.411 ± 1.169
0.0ArgXaa: 0.0 ± 0.0
Ser
5.304SerAla: 5.304 ± 3.111
1.929SerCys: 1.929 ± 0.559
5.304SerAsp: 5.304 ± 1.754
5.304SerGlu: 5.304 ± 1.152
4.339SerPhe: 4.339 ± 1.876
3.375SerGly: 3.375 ± 2.117
0.482SerHis: 0.482 ± 0.234
5.786SerIle: 5.786 ± 1.749
1.929SerLys: 1.929 ± 0.559
5.786SerLeu: 5.786 ± 2.897
2.893SerMet: 2.893 ± 2.053
3.857SerAsn: 3.857 ± 0.505
2.411SerPro: 2.411 ± 1.088
2.411SerGln: 2.411 ± 2.136
5.304SerArg: 5.304 ± 0.708
2.411SerSer: 2.411 ± 1.169
4.822SerThr: 4.822 ± 4.487
9.161SerVal: 9.161 ± 5.105
0.482SerTrp: 0.482 ± 0.234
2.411SerTyr: 2.411 ± 1.169
0.0SerXaa: 0.0 ± 0.0
Thr
5.304ThrAla: 5.304 ± 4.327
0.964ThrCys: 0.964 ± 0.819
1.929ThrAsp: 1.929 ± 2.258
1.929ThrGlu: 1.929 ± 1.308
4.339ThrPhe: 4.339 ± 1.08
1.929ThrGly: 1.929 ± 0.951
1.929ThrHis: 1.929 ± 0.935
3.857ThrIle: 3.857 ± 0.954
2.411ThrLys: 2.411 ± 0.546
5.304ThrLeu: 5.304 ± 1.152
1.446ThrMet: 1.446 ± 0.661
2.893ThrAsn: 2.893 ± 2.034
3.857ThrPro: 3.857 ± 3.586
3.857ThrGln: 3.857 ± 0.505
2.893ThrArg: 2.893 ± 1.868
2.411ThrSer: 2.411 ± 0.94
5.304ThrThr: 5.304 ± 2.901
5.786ThrVal: 5.786 ± 1.949
0.482ThrTrp: 0.482 ± 1.274
2.411ThrTyr: 2.411 ± 0.546
0.0ThrXaa: 0.0 ± 0.0
Val
3.375ValAla: 3.375 ± 1.637
1.929ValCys: 1.929 ± 0.559
6.75ValAsp: 6.75 ± 1.618
3.857ValGlu: 3.857 ± 0.505
4.822ValPhe: 4.822 ± 0.938
1.929ValGly: 1.929 ± 0.935
1.446ValHis: 1.446 ± 0.702
3.857ValIle: 3.857 ± 1.402
3.857ValLys: 3.857 ± 3.276
4.822ValLeu: 4.822 ± 4.095
2.893ValMet: 2.893 ± 1.552
3.857ValAsn: 3.857 ± 0.505
2.411ValPro: 2.411 ± 1.169
4.339ValGln: 4.339 ± 1.983
2.411ValArg: 2.411 ± 0.94
10.608ValSer: 10.608 ± 1.416
5.786ValThr: 5.786 ± 1.971
7.232ValVal: 7.232 ± 0.28
0.964ValTrp: 0.964 ± 0.468
4.339ValTyr: 4.339 ± 1.876
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.0TrpCys: 0.0 ± 0.0
1.446TrpAsp: 1.446 ± 0.702
1.929TrpGlu: 1.929 ± 0.935
0.0TrpPhe: 0.0 ± 0.0
0.482TrpGly: 0.482 ± 0.234
0.0TrpHis: 0.0 ± 0.0
0.482TrpIle: 0.482 ± 0.234
0.482TrpLys: 0.482 ± 1.007
2.411TrpLeu: 2.411 ± 1.088
0.0TrpMet: 0.0 ± 0.0
0.482TrpAsn: 0.482 ± 0.234
0.0TrpPro: 0.0 ± 0.0
0.482TrpGln: 0.482 ± 0.234
0.0TrpArg: 0.0 ± 0.0
0.482TrpSer: 0.482 ± 0.234
0.482TrpThr: 0.482 ± 0.234
1.446TrpVal: 1.446 ± 0.702
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.893TyrAla: 2.893 ± 0.985
1.446TyrCys: 1.446 ± 0.702
4.339TyrAsp: 4.339 ± 1.154
0.482TyrGlu: 0.482 ± 0.234
1.929TyrPhe: 1.929 ± 0.951
0.482TyrGly: 0.482 ± 0.234
0.482TyrHis: 0.482 ± 0.234
1.929TyrIle: 1.929 ± 2.258
0.964TyrLys: 0.964 ± 0.468
6.268TyrLeu: 6.268 ± 2.157
0.482TyrMet: 0.482 ± 0.234
0.482TyrAsn: 0.482 ± 0.234
1.929TyrPro: 1.929 ± 0.935
1.446TyrGln: 1.446 ± 0.702
2.893TyrArg: 2.893 ± 1.403
1.929TyrSer: 1.929 ± 1.308
4.822TyrThr: 4.822 ± 0.427
1.929TyrVal: 1.929 ± 0.559
0.482TyrTrp: 0.482 ± 0.234
1.929TyrTyr: 1.929 ± 0.951
0.482TyrXaa: 0.482 ± 0.234
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.482XaaLeu: 0.482 ± 0.234
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.482XaaGln: 0.482 ± 0.234
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (2075 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski