Amino acid dipepetide frequency for Joinjakaka virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
0.945AlaAla: 0.945 ± 0.85
0.708AlaCys: 0.708 ± 0.568
1.181AlaAsp: 1.181 ± 0.701
1.417AlaGlu: 1.417 ± 0.857
0.472AlaPhe: 0.472 ± 0.256
0.945AlaGly: 0.945 ± 0.512
1.653AlaHis: 1.653 ± 0.982
2.597AlaIle: 2.597 ± 0.617
1.889AlaLys: 1.889 ± 0.39
4.959AlaLeu: 4.959 ± 0.845
0.236AlaMet: 0.236 ± 0.14
3.306AlaAsn: 3.306 ± 1.106
0.472AlaPro: 0.472 ± 0.477
1.417AlaGln: 1.417 ± 0.532
1.181AlaArg: 1.181 ± 0.872
2.834AlaSer: 2.834 ± 0.915
1.653AlaThr: 1.653 ± 0.383
2.597AlaVal: 2.597 ± 0.463
0.708AlaTrp: 0.708 ± 0.504
0.708AlaTyr: 0.708 ± 0.466
0.0AlaXaa: 0.0 ± 0.0
Cys
0.236CysAla: 0.236 ± 0.275
0.0CysCys: 0.0 ± 0.0
1.417CysAsp: 1.417 ± 0.762
0.708CysGlu: 0.708 ± 0.555
0.708CysPhe: 0.708 ± 0.335
0.708CysGly: 0.708 ± 0.504
0.945CysHis: 0.945 ± 0.337
0.472CysIle: 0.472 ± 0.318
1.653CysLys: 1.653 ± 0.969
1.889CysLeu: 1.889 ± 0.612
0.708CysMet: 0.708 ± 0.674
1.417CysAsn: 1.417 ± 0.587
0.945CysPro: 0.945 ± 0.488
0.708CysGln: 0.708 ± 0.408
0.708CysArg: 0.708 ± 0.335
0.945CysSer: 0.945 ± 0.561
1.889CysThr: 1.889 ± 0.501
0.708CysVal: 0.708 ± 0.391
0.472CysTrp: 0.472 ± 0.247
0.472CysTyr: 0.472 ± 0.619
0.0CysXaa: 0.0 ± 0.0
Asp
1.181AspAla: 1.181 ± 0.592
0.236AspCys: 0.236 ± 0.14
3.542AspAsp: 3.542 ± 0.753
4.014AspGlu: 4.014 ± 1.006
3.542AspPhe: 3.542 ± 1.0
2.834AspGly: 2.834 ± 0.91
1.889AspHis: 1.889 ± 0.625
3.306AspIle: 3.306 ± 1.312
2.834AspLys: 2.834 ± 0.704
4.959AspLeu: 4.959 ± 1.585
0.708AspMet: 0.708 ± 0.276
2.361AspAsn: 2.361 ± 0.709
3.306AspPro: 3.306 ± 1.033
2.361AspGln: 2.361 ± 0.765
2.361AspArg: 2.361 ± 0.938
2.597AspSer: 2.597 ± 0.775
1.417AspThr: 1.417 ± 0.842
2.834AspVal: 2.834 ± 0.66
1.653AspTrp: 1.653 ± 0.547
3.306AspTyr: 3.306 ± 0.996
0.0AspXaa: 0.0 ± 0.0
Glu
1.417GluAla: 1.417 ± 0.352
2.361GluCys: 2.361 ± 1.111
2.597GluAsp: 2.597 ± 0.72
5.195GluGlu: 5.195 ± 1.22
2.834GluPhe: 2.834 ± 0.984
3.07GluGly: 3.07 ± 0.512
1.417GluHis: 1.417 ± 0.546
5.195GluIle: 5.195 ± 0.838
4.014GluLys: 4.014 ± 0.9
6.139GluLeu: 6.139 ± 1.854
1.653GluMet: 1.653 ± 0.383
2.125GluAsn: 2.125 ± 0.822
1.417GluPro: 1.417 ± 0.365
1.889GluGln: 1.889 ± 0.319
2.361GluArg: 2.361 ± 0.663
5.667GluSer: 5.667 ± 0.912
3.07GluThr: 3.07 ± 0.464
5.431GluVal: 5.431 ± 1.113
0.708GluTrp: 0.708 ± 0.408
2.361GluTyr: 2.361 ± 1.092
0.0GluXaa: 0.0 ± 0.0
Phe
1.889PheAla: 1.889 ± 0.478
0.472PheCys: 0.472 ± 0.247
1.889PheAsp: 1.889 ± 0.717
3.542PheGlu: 3.542 ± 0.861
3.306PhePhe: 3.306 ± 1.051
3.542PheGly: 3.542 ± 0.831
1.181PheHis: 1.181 ± 0.525
1.181PheIle: 1.181 ± 0.262
6.612PheLys: 6.612 ± 1.561
4.959PheLeu: 4.959 ± 0.981
1.417PheMet: 1.417 ± 0.365
1.653PheAsn: 1.653 ± 1.218
1.417PhePro: 1.417 ± 0.289
3.07PheGln: 3.07 ± 0.856
0.945PheArg: 0.945 ± 0.388
3.306PheSer: 3.306 ± 0.897
2.361PheThr: 2.361 ± 1.141
2.834PheVal: 2.834 ± 1.162
0.708PheTrp: 0.708 ± 0.421
1.653PheTyr: 1.653 ± 0.805
0.0PheXaa: 0.0 ± 0.0
Gly
0.945GlyAla: 0.945 ± 0.417
0.708GlyCys: 0.708 ± 0.46
4.25GlyAsp: 4.25 ± 1.134
1.653GlyGlu: 1.653 ± 0.41
2.597GlyPhe: 2.597 ± 1.123
3.542GlyGly: 3.542 ± 1.231
1.889GlyHis: 1.889 ± 0.555
3.306GlyIle: 3.306 ± 0.637
2.834GlyLys: 2.834 ± 0.932
8.028GlyLeu: 8.028 ± 2.847
0.945GlyMet: 0.945 ± 0.698
4.486GlyAsn: 4.486 ± 2.089
1.653GlyPro: 1.653 ± 0.596
2.361GlyGln: 2.361 ± 0.762
1.181GlyArg: 1.181 ± 0.389
4.25GlySer: 4.25 ± 0.812
3.542GlyThr: 3.542 ± 0.928
3.07GlyVal: 3.07 ± 0.87
0.945GlyTrp: 0.945 ± 0.578
1.889GlyTyr: 1.889 ± 0.671
0.0GlyXaa: 0.0 ± 0.0
His
0.945HisAla: 0.945 ± 0.388
0.236HisCys: 0.236 ± 0.14
1.181HisAsp: 1.181 ± 0.708
1.181HisGlu: 1.181 ± 0.755
1.181HisPhe: 1.181 ± 0.811
0.945HisGly: 0.945 ± 0.395
0.472HisHis: 0.472 ± 0.465
3.07HisIle: 3.07 ± 0.565
1.889HisLys: 1.889 ± 0.744
2.125HisLeu: 2.125 ± 0.53
0.236HisMet: 0.236 ± 0.389
1.417HisAsn: 1.417 ± 0.444
2.361HisPro: 2.361 ± 0.731
0.945HisGln: 0.945 ± 0.388
0.472HisArg: 0.472 ± 0.281
0.945HisSer: 0.945 ± 0.365
1.417HisThr: 1.417 ± 0.622
1.653HisVal: 1.653 ± 0.383
0.472HisTrp: 0.472 ± 0.281
0.945HisTyr: 0.945 ± 0.61
0.0HisXaa: 0.0 ± 0.0
Ile
1.181IleAla: 1.181 ± 0.449
1.181IleCys: 1.181 ± 0.688
4.723IleAsp: 4.723 ± 0.642
5.667IleGlu: 5.667 ± 2.147
4.723IlePhe: 4.723 ± 1.333
7.084IleGly: 7.084 ± 0.951
1.653IleHis: 1.653 ± 0.803
4.486IleIle: 4.486 ± 1.367
5.903IleLys: 5.903 ± 1.165
6.848IleLeu: 6.848 ± 1.345
2.125IleMet: 2.125 ± 1.053
5.667IleAsn: 5.667 ± 0.898
3.778IlePro: 3.778 ± 1.289
1.417IleGln: 1.417 ± 0.552
4.723IleArg: 4.723 ± 1.042
5.195IleSer: 5.195 ± 0.835
2.361IleThr: 2.361 ± 0.824
3.07IleVal: 3.07 ± 0.977
0.708IleTrp: 0.708 ± 0.293
2.361IleTyr: 2.361 ± 0.577
0.0IleXaa: 0.0 ± 0.0
Lys
1.417LysAla: 1.417 ± 0.8
1.417LysCys: 1.417 ± 1.102
2.361LysAsp: 2.361 ± 1.027
6.139LysGlu: 6.139 ± 0.767
1.417LysPhe: 1.417 ± 0.602
3.778LysGly: 3.778 ± 0.845
1.417LysHis: 1.417 ± 0.318
5.667LysIle: 5.667 ± 1.712
5.903LysLys: 5.903 ± 1.241
8.264LysLeu: 8.264 ± 1.331
1.889LysMet: 1.889 ± 0.886
6.848LysAsn: 6.848 ± 1.096
3.542LysPro: 3.542 ± 0.389
2.361LysGln: 2.361 ± 0.859
3.542LysArg: 3.542 ± 0.804
5.903LysSer: 5.903 ± 0.809
5.431LysThr: 5.431 ± 1.405
4.959LysVal: 4.959 ± 0.678
0.472LysTrp: 0.472 ± 0.281
2.361LysTyr: 2.361 ± 0.662
0.0LysXaa: 0.0 ± 0.0
Leu
4.959LeuAla: 4.959 ± 1.624
1.889LeuCys: 1.889 ± 0.928
6.139LeuAsp: 6.139 ± 1.535
6.848LeuGlu: 6.848 ± 1.257
4.959LeuPhe: 4.959 ± 1.118
4.014LeuGly: 4.014 ± 1.561
1.181LeuHis: 1.181 ± 0.524
10.862LeuIle: 10.862 ± 1.799
7.556LeuLys: 7.556 ± 1.041
8.973LeuLeu: 8.973 ± 1.087
4.014LeuMet: 4.014 ± 0.614
5.667LeuAsn: 5.667 ± 1.61
3.778LeuPro: 3.778 ± 0.725
3.306LeuGln: 3.306 ± 0.566
4.486LeuArg: 4.486 ± 1.261
8.501LeuSer: 8.501 ± 1.64
5.431LeuThr: 5.431 ± 1.022
6.139LeuVal: 6.139 ± 0.896
1.181LeuTrp: 1.181 ± 0.793
3.306LeuTyr: 3.306 ± 0.69
0.0LeuXaa: 0.0 ± 0.0
Met
2.125MetAla: 2.125 ± 0.714
0.708MetCys: 0.708 ± 0.293
1.417MetAsp: 1.417 ± 0.581
2.125MetGlu: 2.125 ± 0.502
2.125MetPhe: 2.125 ± 0.848
2.125MetGly: 2.125 ± 0.619
0.0MetHis: 0.0 ± 0.0
1.653MetIle: 1.653 ± 0.601
1.417MetLys: 1.417 ± 0.638
2.361MetLeu: 2.361 ± 0.797
0.945MetMet: 0.945 ± 0.466
1.181MetAsn: 1.181 ± 0.262
0.472MetPro: 0.472 ± 0.247
0.708MetGln: 0.708 ± 0.421
0.945MetArg: 0.945 ± 0.495
2.125MetSer: 2.125 ± 0.606
1.653MetThr: 1.653 ± 0.682
2.361MetVal: 2.361 ± 0.507
0.945MetTrp: 0.945 ± 0.438
0.708MetTyr: 0.708 ± 0.293
0.0MetXaa: 0.0 ± 0.0
Asn
2.597AsnAla: 2.597 ± 0.496
1.653AsnCys: 1.653 ± 0.339
2.597AsnAsp: 2.597 ± 0.584
2.597AsnGlu: 2.597 ± 0.909
2.125AsnPhe: 2.125 ± 0.549
3.542AsnGly: 3.542 ± 1.496
1.181AsnHis: 1.181 ± 0.464
5.903AsnIle: 5.903 ± 1.209
5.667AsnLys: 5.667 ± 0.483
6.139AsnLeu: 6.139 ± 1.031
1.417AsnMet: 1.417 ± 0.4
3.778AsnAsn: 3.778 ± 1.187
2.834AsnPro: 2.834 ± 0.476
2.597AsnGln: 2.597 ± 0.55
2.125AsnArg: 2.125 ± 1.383
3.778AsnSer: 3.778 ± 0.634
2.361AsnThr: 2.361 ± 1.42
3.306AsnVal: 3.306 ± 1.171
2.361AsnTrp: 2.361 ± 0.731
2.597AsnTyr: 2.597 ± 0.78
0.0AsnXaa: 0.0 ± 0.0
Pro
1.417ProAla: 1.417 ± 0.523
0.236ProCys: 0.236 ± 0.346
1.889ProAsp: 1.889 ± 0.684
2.125ProGlu: 2.125 ± 0.688
1.417ProPhe: 1.417 ± 0.816
1.653ProGly: 1.653 ± 0.733
1.653ProHis: 1.653 ± 0.567
4.014ProIle: 4.014 ± 1.203
3.542ProLys: 3.542 ± 0.843
3.542ProLeu: 3.542 ± 0.534
1.417ProMet: 1.417 ± 0.456
1.417ProAsn: 1.417 ± 0.587
2.361ProPro: 2.361 ± 1.533
1.181ProGln: 1.181 ± 0.52
0.945ProArg: 0.945 ± 0.388
4.959ProSer: 4.959 ± 0.902
1.889ProThr: 1.889 ± 0.453
3.07ProVal: 3.07 ± 1.362
0.472ProTrp: 0.472 ± 0.256
2.834ProTyr: 2.834 ± 0.728
0.0ProXaa: 0.0 ± 0.0
Gln
2.125GlnAla: 2.125 ± 0.806
0.708GlnCys: 0.708 ± 0.35
1.417GlnAsp: 1.417 ± 0.426
1.417GlnGlu: 1.417 ± 0.602
1.653GlnPhe: 1.653 ± 0.391
1.653GlnGly: 1.653 ± 0.551
0.708GlnHis: 0.708 ± 0.579
3.07GlnIle: 3.07 ± 0.65
3.07GlnLys: 3.07 ± 1.051
3.542GlnLeu: 3.542 ± 1.289
0.945GlnMet: 0.945 ± 0.472
2.125GlnAsn: 2.125 ± 1.036
1.653GlnPro: 1.653 ± 0.476
0.708GlnGln: 0.708 ± 0.276
0.945GlnArg: 0.945 ± 0.462
3.306GlnSer: 3.306 ± 1.144
2.361GlnThr: 2.361 ± 0.713
2.125GlnVal: 2.125 ± 0.838
0.708GlnTrp: 0.708 ± 0.276
1.181GlnTyr: 1.181 ± 0.262
0.0GlnXaa: 0.0 ± 0.0
Arg
1.889ArgAla: 1.889 ± 0.573
0.708ArgCys: 0.708 ± 0.293
1.181ArgAsp: 1.181 ± 0.591
2.361ArgGlu: 2.361 ± 0.929
4.014ArgPhe: 4.014 ± 1.315
2.361ArgGly: 2.361 ± 0.7
1.181ArgHis: 1.181 ± 0.442
1.653ArgIle: 1.653 ± 0.641
3.07ArgLys: 3.07 ± 0.78
3.306ArgLeu: 3.306 ± 0.819
1.417ArgMet: 1.417 ± 0.716
3.07ArgAsn: 3.07 ± 0.839
1.653ArgPro: 1.653 ± 0.674
2.125ArgGln: 2.125 ± 0.552
1.417ArgArg: 1.417 ± 0.683
1.889ArgSer: 1.889 ± 0.452
2.834ArgThr: 2.834 ± 1.192
2.361ArgVal: 2.361 ± 0.77
1.181ArgTrp: 1.181 ± 0.668
1.417ArgTyr: 1.417 ± 0.742
0.0ArgXaa: 0.0 ± 0.0
Ser
1.889SerAla: 1.889 ± 0.833
0.708SerCys: 0.708 ± 0.293
5.195SerAsp: 5.195 ± 1.519
4.959SerGlu: 4.959 ± 0.787
2.834SerPhe: 2.834 ± 0.739
3.542SerGly: 3.542 ± 0.777
1.653SerHis: 1.653 ± 0.574
6.375SerIle: 6.375 ± 1.347
4.25SerLys: 4.25 ± 0.852
11.57SerLeu: 11.57 ± 1.638
1.181SerMet: 1.181 ± 0.701
4.486SerAsn: 4.486 ± 1.018
2.125SerPro: 2.125 ± 0.768
1.889SerGln: 1.889 ± 0.717
3.778SerArg: 3.778 ± 0.765
4.959SerSer: 4.959 ± 1.007
4.014SerThr: 4.014 ± 1.046
4.25SerVal: 4.25 ± 0.543
2.597SerTrp: 2.597 ± 1.021
3.542SerTyr: 3.542 ± 0.74
0.0SerXaa: 0.0 ± 0.0
Thr
0.945ThrAla: 0.945 ± 0.707
0.472ThrCys: 0.472 ± 0.438
2.834ThrAsp: 2.834 ± 0.644
2.125ThrGlu: 2.125 ± 0.681
2.361ThrPhe: 2.361 ± 1.274
2.834ThrGly: 2.834 ± 0.777
1.181ThrHis: 1.181 ± 1.133
3.542ThrIle: 3.542 ± 0.921
4.723ThrLys: 4.723 ± 1.233
5.195ThrLeu: 5.195 ± 0.893
1.653ThrMet: 1.653 ± 0.761
2.834ThrAsn: 2.834 ± 0.638
3.542ThrPro: 3.542 ± 1.088
1.417ThrGln: 1.417 ± 0.722
3.07ThrArg: 3.07 ± 0.966
4.959ThrSer: 4.959 ± 1.778
4.486ThrThr: 4.486 ± 1.55
3.07ThrVal: 3.07 ± 1.118
1.653ThrTrp: 1.653 ± 0.354
1.653ThrTyr: 1.653 ± 0.606
0.0ThrXaa: 0.0 ± 0.0
Val
1.653ValAla: 1.653 ± 0.448
1.653ValCys: 1.653 ± 0.687
2.834ValAsp: 2.834 ± 1.364
3.306ValGlu: 3.306 ± 0.95
3.07ValPhe: 3.07 ± 0.836
1.889ValGly: 1.889 ± 0.898
1.653ValHis: 1.653 ± 0.787
5.195ValIle: 5.195 ± 1.855
4.959ValLys: 4.959 ± 1.074
6.139ValLeu: 6.139 ± 0.735
2.834ValMet: 2.834 ± 0.66
4.723ValAsn: 4.723 ± 1.293
2.597ValPro: 2.597 ± 0.614
2.125ValGln: 2.125 ± 0.826
3.542ValArg: 3.542 ± 0.46
4.25ValSer: 4.25 ± 0.747
3.07ValThr: 3.07 ± 1.306
2.597ValVal: 2.597 ± 0.832
1.181ValTrp: 1.181 ± 0.615
2.361ValTyr: 2.361 ± 0.975
0.0ValXaa: 0.0 ± 0.0
Trp
0.708TrpAla: 0.708 ± 0.276
0.472TrpCys: 0.472 ± 0.256
1.653TrpAsp: 1.653 ± 0.574
1.417TrpGlu: 1.417 ± 0.842
1.181TrpPhe: 1.181 ± 0.355
2.125TrpGly: 2.125 ± 0.633
0.236TrpHis: 0.236 ± 0.14
1.417TrpIle: 1.417 ± 0.444
1.181TrpLys: 1.181 ± 0.389
0.708TrpLeu: 0.708 ± 0.276
1.181TrpMet: 1.181 ± 0.513
1.181TrpAsn: 1.181 ± 0.636
0.708TrpPro: 0.708 ± 0.335
0.0TrpGln: 0.0 ± 0.0
0.945TrpArg: 0.945 ± 0.395
1.889TrpSer: 1.889 ± 0.622
0.708TrpThr: 0.708 ± 0.568
2.125TrpVal: 2.125 ± 1.075
0.708TrpTrp: 0.708 ± 0.504
0.236TrpTyr: 0.236 ± 0.275
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.417TyrAla: 1.417 ± 0.466
1.181TyrCys: 1.181 ± 0.942
0.945TyrAsp: 0.945 ± 0.421
2.125TyrGlu: 2.125 ± 0.776
1.417TyrPhe: 1.417 ± 0.503
1.889TyrGly: 1.889 ± 0.524
0.945TyrHis: 0.945 ± 0.395
1.889TyrIle: 1.889 ± 1.074
2.125TyrLys: 2.125 ± 0.421
3.542TyrLeu: 3.542 ± 0.842
0.945TyrMet: 0.945 ± 0.41
1.653TyrAsn: 1.653 ± 0.452
1.417TyrPro: 1.417 ± 0.601
2.834TyrGln: 2.834 ± 0.811
1.417TyrArg: 1.417 ± 0.83
3.542TyrSer: 3.542 ± 0.988
2.597TyrThr: 2.597 ± 0.788
3.07TyrVal: 3.07 ± 0.513
0.945TyrTrp: 0.945 ± 0.381
2.597TyrTyr: 2.597 ± 1.065
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 9 proteins (4236 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski