Treponema primitia (strain ATCC BAA-887 / DSM 12427 / ZAS-2)

Taxonomy: cellular organisms; Bacteria; Spirochaetes; Spirochaetia; Spirochaetales; Treponemataceae; Treponema; Treponema primitia

Average proteome isoelectric point is 6.38

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 3512 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|F5YRI1|F5YRI1_TREPZ Uncharacterized protein OS=Treponema primitia (strain ATCC BAA-887 / DSM 12427 / ZAS-2) OX=545694 GN=TREPR_1248 PE=4 SV=1
MM1 pKa = 7.57KK2 pKa = 10.72LFGNKK7 pKa = 7.39QRR9 pKa = 11.84ALSPITCAAGIVLLAGLLALTGCANPLNSPADD41 pKa = 3.6NTVGQGLGLVTITIGEE57 pKa = 4.12TGARR61 pKa = 11.84NLYY64 pKa = 9.41PNPTGFTNYY73 pKa = 9.28EE74 pKa = 3.86LSFAPISGPAFYY86 pKa = 10.41GAIPASVAKK95 pKa = 9.93SDD97 pKa = 3.87SSFPPISLIPGTWTITAKK115 pKa = 10.45AYY117 pKa = 10.67NGSTQVAEE125 pKa = 4.24TAVEE129 pKa = 4.28VTVVAGEE136 pKa = 4.33LVTKK140 pKa = 10.63NIILKK145 pKa = 9.67PITGAGAGTFDD156 pKa = 4.73YY157 pKa = 10.85EE158 pKa = 4.29VTNADD163 pKa = 5.13DD164 pKa = 3.94VDD166 pKa = 4.4FDD168 pKa = 5.12DD169 pKa = 6.33GSEE172 pKa = 4.11LTLSDD177 pKa = 4.26LSGNPIYY184 pKa = 10.19TYY186 pKa = 10.92NLSSVQSGTDD196 pKa = 3.34SVPAGIYY203 pKa = 10.11DD204 pKa = 3.74LSIVIKK210 pKa = 10.23KK211 pKa = 10.56DD212 pKa = 3.13GGITGTTEE220 pKa = 3.75VVFIYY225 pKa = 10.39PGLTTVAHH233 pKa = 6.82FIFGNGEE240 pKa = 4.01IYY242 pKa = 10.7SGTTSNPAFVATSLSKK258 pKa = 10.08TEE260 pKa = 4.04VVQPSITFEE269 pKa = 4.28LKK271 pKa = 10.58NDD273 pKa = 3.86TEE275 pKa = 4.5LTGATWKK282 pKa = 10.93VYY284 pKa = 10.18DD285 pKa = 5.01AEE287 pKa = 5.99DD288 pKa = 4.64DD289 pKa = 4.18GDD291 pKa = 5.53DD292 pKa = 3.5ITDD295 pKa = 3.67TVVPTIEE302 pKa = 4.39SSNKK306 pKa = 8.36LTLTAVSNNITAGDD320 pKa = 3.77YY321 pKa = 9.27WVTAQAPGKK330 pKa = 9.78FEE332 pKa = 3.95SATRR336 pKa = 11.84VKK338 pKa = 10.22LTVEE342 pKa = 4.06PNPLQNEE349 pKa = 4.44TFTVVDD355 pKa = 4.97GIGDD359 pKa = 3.8PGLNNIYY366 pKa = 10.71LEE368 pKa = 4.39GGFVKK373 pKa = 10.43IGDD376 pKa = 4.2DD377 pKa = 3.45DD378 pKa = 5.05GGFIDD383 pKa = 5.5HH384 pKa = 7.07NPDD387 pKa = 2.86TDD389 pKa = 3.72PAYY392 pKa = 10.03KK393 pKa = 10.09PLAVFLGLTGVEE405 pKa = 4.31PDD407 pKa = 3.58DD408 pKa = 4.4QIVFDD413 pKa = 4.86EE414 pKa = 4.3YY415 pKa = 11.82GKK417 pKa = 10.06ILKK420 pKa = 8.04LTKK423 pKa = 10.17VDD425 pKa = 2.99ITYY428 pKa = 10.4DD429 pKa = 2.9ITFAVDD435 pKa = 4.29DD436 pKa = 4.85KK437 pKa = 10.82YY438 pKa = 11.6LPAIADD444 pKa = 3.77VLTLTGNASKK454 pKa = 10.73SFEE457 pKa = 4.24VTGDD461 pKa = 3.33ALTGKK466 pKa = 7.74TVILDD471 pKa = 3.79STSSPTYY478 pKa = 8.98NFYY481 pKa = 10.97GVSVLPYY488 pKa = 8.72DD489 pKa = 4.1TNDD492 pKa = 3.19VTISAEE498 pKa = 4.92DD499 pKa = 4.32DD500 pKa = 3.59DD501 pKa = 4.69TDD503 pKa = 4.01GKK505 pKa = 11.23VVTLLDD511 pKa = 4.19GGSADD516 pKa = 3.47ATVSVLDD523 pKa = 3.76EE524 pKa = 4.57AVDD527 pKa = 3.73KK528 pKa = 11.32LVLGTNAPSAISNEE542 pKa = 3.77KK543 pKa = 9.97SGLVIDD549 pKa = 4.28VGTNAGITITATQPTTVVTDD569 pKa = 3.75KK570 pKa = 11.06LATGTVTVDD579 pKa = 3.99GYY581 pKa = 9.63STAAITIDD589 pKa = 3.62GVSITPVGYY598 pKa = 9.24TDD600 pKa = 6.04AIVTKK605 pKa = 9.44TDD607 pKa = 3.45YY608 pKa = 9.88YY609 pKa = 10.89TLEE612 pKa = 5.11LDD614 pKa = 5.02AGDD617 pKa = 3.79TTATVAIEE625 pKa = 3.95YY626 pKa = 10.43DD627 pKa = 3.63SAITEE632 pKa = 4.19LTLVDD637 pKa = 4.04TNLEE641 pKa = 4.46AISNANTATVINVGSISGVEE661 pKa = 3.46ITAAVDD667 pKa = 3.43TTVVTTEE674 pKa = 4.38LSDD677 pKa = 3.72SNTVVLIGDD686 pKa = 3.6KK687 pKa = 10.76TFTLLVLDD695 pKa = 4.67DD696 pKa = 5.18GGYY699 pKa = 10.86EE700 pKa = 4.49DD701 pKa = 6.13DD702 pKa = 4.3PTPGTVTGSTNGYY715 pKa = 9.79VYY717 pKa = 10.38TYY719 pKa = 11.15LNDD722 pKa = 3.58NGNEE726 pKa = 4.0NTEE729 pKa = 4.13FAPIDD734 pKa = 4.19DD735 pKa = 5.37DD736 pKa = 5.11SFSLTSDD743 pKa = 3.02SGTVTVTVSDD753 pKa = 3.53ITPP756 pKa = 3.46

Molecular weight: 78.72 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|F5YLI7|F5YLI7_TREPZ Precorrin-2 dehydrogenase OS=Treponema primitia (strain ATCC BAA-887 / DSM 12427 / ZAS-2) OX=545694 GN=TREPR_0259 PE=4 SV=1
MM1 pKa = 7.04KK2 pKa = 10.01TVDD5 pKa = 3.27PVQAYY10 pKa = 8.89RR11 pKa = 11.84AIRR14 pKa = 11.84KK15 pKa = 9.24RR16 pKa = 11.84CFLLGLLLWVALVLAVIFTLGMGAMDD42 pKa = 4.48IPASSILRR50 pKa = 11.84ILSAKK55 pKa = 9.93LRR57 pKa = 11.84TAFFGPVGSPEE68 pKa = 3.87ALAGISSGMVAVVWEE83 pKa = 4.14LRR85 pKa = 11.84LPRR88 pKa = 11.84ILLSILAGAGLAVAGVIFQGILQNPLADD116 pKa = 4.89PYY118 pKa = 11.1TLGISTGAAFGASLAIFFNITLGLLLPVSSAALVFAALTLALVLLIAQRR167 pKa = 11.84SSGLVSANLIMAGIILSAILSAGISFLKK195 pKa = 9.83MLSGEE200 pKa = 4.19NVGAIVFWLMGSLSAKK216 pKa = 9.21GWNEE220 pKa = 3.5ALLLATVVPAALVLARR236 pKa = 11.84IFAADD241 pKa = 4.23LNILTLGSRR250 pKa = 11.84SAEE253 pKa = 4.0SLGVQVKK260 pKa = 7.83RR261 pKa = 11.84TRR263 pKa = 11.84LFYY266 pKa = 11.0LFLGATISAVCVSTCGVIGFVGLIVPHH293 pKa = 6.74LLRR296 pKa = 11.84MAVTSDD302 pKa = 2.91NRR304 pKa = 11.84LLIPLSALLGGLLLCAADD322 pKa = 3.7TFARR326 pKa = 11.84LLSGGEE332 pKa = 3.88IPVGVLTTLLGGPFFIFIFLRR353 pKa = 11.84QKK355 pKa = 10.58GGRR358 pKa = 11.84GLL360 pKa = 3.58

Molecular weight: 37.38 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

3512

0

3512

1208744

30

6174

344.2

38.06

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

8.727 ± 0.052

0.989 ± 0.018

5.433 ± 0.035

6.495 ± 0.049

4.497 ± 0.033

7.972 ± 0.048

1.533 ± 0.018

7.241 ± 0.04

5.52 ± 0.051

9.84 ± 0.053

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.255 ± 0.023

4.091 ± 0.032

4.506 ± 0.032

2.962 ± 0.023

5.277 ± 0.044

6.345 ± 0.039

5.489 ± 0.072

6.298 ± 0.039

1.063 ± 0.016

3.466 ± 0.029
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski