Amino acid dipepetide frequency for Beihai sobemo-like virus 16

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
8.704AlaAla: 8.704 ± 2.38
0.0AlaCys: 0.0 ± 0.0
5.803AlaAsp: 5.803 ± 0.929
4.836AlaGlu: 4.836 ± 1.527
2.901AlaPhe: 2.901 ± 1.451
3.868AlaGly: 3.868 ± 0.038
0.967AlaHis: 0.967 ± 0.484
4.836AlaIle: 4.836 ± 1.527
3.868AlaLys: 3.868 ± 0.038
3.868AlaLeu: 3.868 ± 2.011
1.934AlaMet: 1.934 ± 1.005
0.967AlaAsn: 0.967 ± 1.489
6.77AlaPro: 6.77 ± 0.56
4.836AlaGln: 4.836 ± 2.418
3.868AlaArg: 3.868 ± 0.038
8.704AlaSer: 8.704 ± 0.407
2.901AlaThr: 2.901 ± 0.522
6.77AlaVal: 6.77 ± 1.413
0.0AlaTrp: 0.0 ± 0.0
3.868AlaTyr: 3.868 ± 2.011
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.967CysCys: 0.967 ± 1.489
0.0CysAsp: 0.0 ± 0.0
0.0CysGlu: 0.0 ± 0.0
0.967CysPhe: 0.967 ± 0.484
1.934CysGly: 1.934 ± 1.005
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
0.0CysLys: 0.0 ± 0.0
1.934CysLeu: 1.934 ± 1.005
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.967CysPro: 0.967 ± 0.484
0.967CysGln: 0.967 ± 0.484
0.967CysArg: 0.967 ± 0.484
0.967CysSer: 0.967 ± 1.489
0.967CysThr: 0.967 ± 1.489
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
5.803AspAla: 5.803 ± 2.901
1.934AspCys: 1.934 ± 1.005
6.77AspAsp: 6.77 ± 1.413
1.934AspGlu: 1.934 ± 0.967
1.934AspPhe: 1.934 ± 0.967
1.934AspGly: 1.934 ± 1.005
0.0AspHis: 0.0 ± 0.0
2.901AspIle: 2.901 ± 1.451
1.934AspLys: 1.934 ± 1.005
4.836AspLeu: 4.836 ± 1.527
0.0AspMet: 0.0 ± 0.0
1.934AspAsn: 1.934 ± 2.978
3.868AspPro: 3.868 ± 0.038
2.901AspGln: 2.901 ± 1.451
1.934AspArg: 1.934 ± 1.005
5.803AspSer: 5.803 ± 2.901
3.868AspThr: 3.868 ± 0.038
4.836AspVal: 4.836 ± 2.418
1.934AspTrp: 1.934 ± 2.978
1.934AspTyr: 1.934 ± 0.967
0.0AspXaa: 0.0 ± 0.0
Glu
1.934GluAla: 1.934 ± 1.005
0.0GluCys: 0.0 ± 0.0
2.901GluAsp: 2.901 ± 1.451
0.967GluGlu: 0.967 ± 0.484
2.901GluPhe: 2.901 ± 4.467
1.934GluGly: 1.934 ± 0.967
0.0GluHis: 0.0 ± 0.0
1.934GluIle: 1.934 ± 0.967
4.836GluLys: 4.836 ± 1.527
7.737GluLeu: 7.737 ± 0.076
0.967GluMet: 0.967 ± 0.484
4.836GluAsn: 4.836 ± 2.418
3.868GluPro: 3.868 ± 0.038
0.967GluGln: 0.967 ± 0.484
1.934GluArg: 1.934 ± 0.967
2.901GluSer: 2.901 ± 1.451
3.868GluThr: 3.868 ± 0.038
1.934GluVal: 1.934 ± 0.967
0.0GluTrp: 0.0 ± 0.0
3.868GluTyr: 3.868 ± 1.934
0.0GluXaa: 0.0 ± 0.0
Phe
0.967PheAla: 0.967 ± 0.484
0.967PheCys: 0.967 ± 1.489
1.934PheAsp: 1.934 ± 1.005
1.934PheGlu: 1.934 ± 1.005
4.836PhePhe: 4.836 ± 2.418
0.0PheGly: 0.0 ± 0.0
3.868PheHis: 3.868 ± 2.011
1.934PheIle: 1.934 ± 0.967
1.934PheLys: 1.934 ± 0.967
5.803PheLeu: 5.803 ± 2.901
0.967PheMet: 0.967 ± 0.484
0.967PheAsn: 0.967 ± 0.484
0.0PhePro: 0.0 ± 0.0
0.967PheGln: 0.967 ± 0.484
0.967PheArg: 0.967 ± 1.489
3.868PheSer: 3.868 ± 0.038
2.901PheThr: 2.901 ± 2.494
2.901PheVal: 2.901 ± 0.522
0.0PheTrp: 0.0 ± 0.0
0.967PheTyr: 0.967 ± 0.484
0.0PheXaa: 0.0 ± 0.0
Gly
4.836GlyAla: 4.836 ± 0.445
0.0GlyCys: 0.0 ± 0.0
2.901GlyAsp: 2.901 ± 0.522
2.901GlyGlu: 2.901 ± 1.451
3.868GlyPhe: 3.868 ± 1.934
2.901GlyGly: 2.901 ± 2.494
2.901GlyHis: 2.901 ± 0.522
2.901GlyIle: 2.901 ± 2.494
0.0GlyLys: 0.0 ± 0.0
2.901GlyLeu: 2.901 ± 0.522
1.934GlyMet: 1.934 ± 1.005
0.967GlyAsn: 0.967 ± 0.484
3.868GlyPro: 3.868 ± 0.038
1.934GlyGln: 1.934 ± 0.967
1.934GlyArg: 1.934 ± 0.967
3.868GlySer: 3.868 ± 2.011
1.934GlyThr: 1.934 ± 0.967
4.836GlyVal: 4.836 ± 1.527
2.901GlyTrp: 2.901 ± 4.467
0.967GlyTyr: 0.967 ± 0.484
0.0GlyXaa: 0.0 ± 0.0
His
3.868HisAla: 3.868 ± 1.934
0.967HisCys: 0.967 ± 1.489
0.967HisAsp: 0.967 ± 1.489
1.934HisGlu: 1.934 ± 2.978
0.0HisPhe: 0.0 ± 0.0
0.0HisGly: 0.0 ± 0.0
0.967HisHis: 0.967 ± 1.489
1.934HisIle: 1.934 ± 1.005
0.0HisLys: 0.0 ± 0.0
0.967HisLeu: 0.967 ± 1.489
0.967HisMet: 0.967 ± 0.484
0.967HisAsn: 0.967 ± 0.484
2.901HisPro: 2.901 ± 0.522
0.0HisGln: 0.0 ± 0.0
0.0HisArg: 0.0 ± 0.0
3.868HisSer: 3.868 ± 0.038
1.934HisThr: 1.934 ± 0.967
0.0HisVal: 0.0 ± 0.0
0.0HisTrp: 0.0 ± 0.0
0.967HisTyr: 0.967 ± 0.484
0.0HisXaa: 0.0 ± 0.0
Ile
2.901IleAla: 2.901 ± 2.494
0.0IleCys: 0.0 ± 0.0
4.836IleAsp: 4.836 ± 2.418
0.967IleGlu: 0.967 ± 0.484
1.934IlePhe: 1.934 ± 0.967
4.836IleGly: 4.836 ± 3.499
1.934IleHis: 1.934 ± 0.967
1.934IleIle: 1.934 ± 1.005
0.967IleLys: 0.967 ± 1.489
4.836IleLeu: 4.836 ± 1.527
1.934IleMet: 1.934 ± 1.005
0.0IleAsn: 0.0 ± 0.0
3.868IlePro: 3.868 ± 0.038
2.901IleGln: 2.901 ± 2.494
2.901IleArg: 2.901 ± 0.522
2.901IleSer: 2.901 ± 0.522
0.967IleThr: 0.967 ± 0.484
2.901IleVal: 2.901 ± 1.451
0.967IleTrp: 0.967 ± 0.484
0.0IleTyr: 0.0 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
2.901LysAla: 2.901 ± 0.522
0.0LysCys: 0.0 ± 0.0
3.868LysAsp: 3.868 ± 0.038
0.967LysGlu: 0.967 ± 0.484
0.967LysPhe: 0.967 ± 0.484
1.934LysGly: 1.934 ± 0.967
0.967LysHis: 0.967 ± 1.489
0.0LysIle: 0.0 ± 0.0
0.967LysLys: 0.967 ± 0.484
5.803LysLeu: 5.803 ± 0.929
1.934LysMet: 1.934 ± 0.967
0.0LysAsn: 0.0 ± 0.0
1.934LysPro: 1.934 ± 1.005
0.0LysGln: 0.0 ± 0.0
0.967LysArg: 0.967 ± 0.484
5.803LysSer: 5.803 ± 0.929
3.868LysThr: 3.868 ± 0.038
4.836LysVal: 4.836 ± 0.445
0.967LysTrp: 0.967 ± 0.484
0.967LysTyr: 0.967 ± 1.489
0.0LysXaa: 0.0 ± 0.0
Leu
7.737LeuAla: 7.737 ± 2.049
1.934LeuCys: 1.934 ± 1.005
1.934LeuAsp: 1.934 ± 0.967
4.836LeuGlu: 4.836 ± 0.445
2.901LeuPhe: 2.901 ± 0.522
6.77LeuGly: 6.77 ± 2.532
0.0LeuHis: 0.0 ± 0.0
0.967LeuIle: 0.967 ± 1.489
5.803LeuLys: 5.803 ± 0.929
8.704LeuLeu: 8.704 ± 4.352
1.934LeuMet: 1.934 ± 0.783
3.868LeuAsn: 3.868 ± 1.934
9.671LeuPro: 9.671 ± 1.082
7.737LeuGln: 7.737 ± 2.049
9.671LeuArg: 9.671 ± 0.891
9.671LeuSer: 9.671 ± 1.082
3.868LeuThr: 3.868 ± 0.038
6.77LeuVal: 6.77 ± 2.532
2.901LeuTrp: 2.901 ± 0.522
0.967LeuTyr: 0.967 ± 1.489
0.0LeuXaa: 0.0 ± 0.0
Met
0.0MetAla: 0.0 ± 0.0
0.0MetCys: 0.0 ± 0.0
0.0MetAsp: 0.0 ± 0.0
4.836MetGlu: 4.836 ± 3.499
0.967MetPhe: 0.967 ± 1.489
0.967MetGly: 0.967 ± 1.489
0.967MetHis: 0.967 ± 0.484
1.934MetIle: 1.934 ± 0.967
1.934MetLys: 1.934 ± 0.967
0.967MetLeu: 0.967 ± 1.489
0.967MetMet: 0.967 ± 1.489
0.0MetAsn: 0.0 ± 0.0
0.0MetPro: 0.0 ± 0.0
2.901MetGln: 2.901 ± 1.451
1.934MetArg: 1.934 ± 2.978
1.934MetSer: 1.934 ± 0.967
1.934MetThr: 1.934 ± 0.967
0.967MetVal: 0.967 ± 0.484
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
1.934AsnAla: 1.934 ± 1.005
0.0AsnCys: 0.0 ± 0.0
0.967AsnAsp: 0.967 ± 0.484
2.901AsnGlu: 2.901 ± 1.451
0.967AsnPhe: 0.967 ± 0.484
2.901AsnGly: 2.901 ± 0.522
2.901AsnHis: 2.901 ± 0.522
0.0AsnIle: 0.0 ± 0.0
2.901AsnLys: 2.901 ± 0.522
3.868AsnLeu: 3.868 ± 0.038
0.0AsnMet: 0.0 ± 0.0
0.967AsnAsn: 0.967 ± 0.484
2.901AsnPro: 2.901 ± 1.451
2.901AsnGln: 2.901 ± 1.451
0.967AsnArg: 0.967 ± 0.484
4.836AsnSer: 4.836 ± 1.527
0.967AsnThr: 0.967 ± 1.489
0.967AsnVal: 0.967 ± 0.484
0.967AsnTrp: 0.967 ± 0.484
0.0AsnTyr: 0.0 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
4.836ProAla: 4.836 ± 1.527
0.0ProCys: 0.0 ± 0.0
3.868ProAsp: 3.868 ± 0.038
2.901ProGlu: 2.901 ± 1.451
0.967ProPhe: 0.967 ± 0.484
6.77ProGly: 6.77 ± 0.56
1.934ProHis: 1.934 ± 1.005
5.803ProIle: 5.803 ± 1.043
1.934ProLys: 1.934 ± 0.967
5.803ProLeu: 5.803 ± 0.929
0.0ProMet: 0.0 ± 0.0
1.934ProAsn: 1.934 ± 1.005
8.704ProPro: 8.704 ± 4.352
4.836ProGln: 4.836 ± 2.418
2.901ProArg: 2.901 ± 2.494
9.671ProSer: 9.671 ± 2.863
4.836ProThr: 4.836 ± 2.418
4.836ProVal: 4.836 ± 0.445
0.967ProTrp: 0.967 ± 1.489
0.0ProTyr: 0.0 ± 0.0
0.0ProXaa: 0.0 ± 0.0
Gln
3.868GlnAla: 3.868 ± 0.038
0.0GlnCys: 0.0 ± 0.0
2.901GlnAsp: 2.901 ± 2.494
1.934GlnGlu: 1.934 ± 0.967
1.934GlnPhe: 1.934 ± 1.005
3.868GlnGly: 3.868 ± 1.934
0.967GlnHis: 0.967 ± 0.484
1.934GlnIle: 1.934 ± 0.967
1.934GlnLys: 1.934 ± 0.967
6.77GlnLeu: 6.77 ± 2.532
0.0GlnMet: 0.0 ± 0.0
1.934GlnAsn: 1.934 ± 0.967
2.901GlnPro: 2.901 ± 0.522
1.934GlnGln: 1.934 ± 0.967
3.868GlnArg: 3.868 ± 1.934
1.934GlnSer: 1.934 ± 0.967
1.934GlnThr: 1.934 ± 0.967
2.901GlnVal: 2.901 ± 1.451
0.0GlnTrp: 0.0 ± 0.0
0.967GlnTyr: 0.967 ± 1.489
0.0GlnXaa: 0.0 ± 0.0
Arg
0.0ArgAla: 0.0 ± 0.0
0.0ArgCys: 0.0 ± 0.0
3.868ArgAsp: 3.868 ± 1.934
8.704ArgGlu: 8.704 ± 4.352
0.967ArgPhe: 0.967 ± 0.484
1.934ArgGly: 1.934 ± 1.005
1.934ArgHis: 1.934 ± 1.005
0.0ArgIle: 0.0 ± 0.0
4.836ArgLys: 4.836 ± 2.418
4.836ArgLeu: 4.836 ± 3.499
0.967ArgMet: 0.967 ± 0.484
2.901ArgAsn: 2.901 ± 0.522
4.836ArgPro: 4.836 ± 0.445
1.934ArgGln: 1.934 ± 1.005
9.671ArgArg: 9.671 ± 4.836
5.803ArgSer: 5.803 ± 0.929
2.901ArgThr: 2.901 ± 0.522
1.934ArgVal: 1.934 ± 1.005
0.0ArgTrp: 0.0 ± 0.0
2.901ArgTyr: 2.901 ± 1.451
0.0ArgXaa: 0.0 ± 0.0
Ser
4.836SerAla: 4.836 ± 2.418
0.967SerCys: 0.967 ± 0.484
5.803SerAsp: 5.803 ± 2.901
0.967SerGlu: 0.967 ± 0.484
4.836SerPhe: 4.836 ± 3.499
4.836SerGly: 4.836 ± 0.445
2.901SerHis: 2.901 ± 0.522
3.868SerIle: 3.868 ± 3.983
2.901SerLys: 2.901 ± 1.451
7.737SerLeu: 7.737 ± 1.896
0.967SerMet: 0.967 ± 1.489
6.77SerAsn: 6.77 ± 1.413
7.737SerPro: 7.737 ± 1.896
1.934SerGln: 1.934 ± 0.967
8.704SerArg: 8.704 ± 2.38
19.342SerSer: 19.342 ± 5.727
8.704SerThr: 8.704 ± 2.38
4.836SerVal: 4.836 ± 1.527
1.934SerTrp: 1.934 ± 0.967
4.836SerTyr: 4.836 ± 3.499
0.0SerXaa: 0.0 ± 0.0
Thr
8.704ThrAla: 8.704 ± 0.407
0.967ThrCys: 0.967 ± 0.484
3.868ThrAsp: 3.868 ± 0.038
2.901ThrGlu: 2.901 ± 1.451
2.901ThrPhe: 2.901 ± 0.522
0.967ThrGly: 0.967 ± 0.484
0.0ThrHis: 0.0 ± 0.0
6.77ThrIle: 6.77 ± 2.532
0.967ThrLys: 0.967 ± 0.484
5.803ThrLeu: 5.803 ± 1.043
0.967ThrMet: 0.967 ± 0.484
0.967ThrAsn: 0.967 ± 0.484
5.803ThrPro: 5.803 ± 0.929
0.967ThrGln: 0.967 ± 0.484
1.934ThrArg: 1.934 ± 0.967
3.868ThrSer: 3.868 ± 1.934
3.868ThrThr: 3.868 ± 1.934
4.836ThrVal: 4.836 ± 1.527
0.0ThrTrp: 0.0 ± 0.0
0.967ThrTyr: 0.967 ± 0.484
0.0ThrXaa: 0.0 ± 0.0
Val
7.737ValAla: 7.737 ± 2.049
0.967ValCys: 0.967 ± 0.484
3.868ValAsp: 3.868 ± 2.011
2.901ValGlu: 2.901 ± 0.522
0.0ValPhe: 0.0 ± 0.0
2.901ValGly: 2.901 ± 1.451
0.0ValHis: 0.0 ± 0.0
1.934ValIle: 1.934 ± 0.967
0.967ValLys: 0.967 ± 1.489
8.704ValLeu: 8.704 ± 2.38
2.901ValMet: 2.901 ± 1.451
2.901ValAsn: 2.901 ± 0.522
1.934ValPro: 1.934 ± 0.967
1.934ValGln: 1.934 ± 2.978
3.868ValArg: 3.868 ± 1.934
6.77ValSer: 6.77 ± 1.413
4.836ValThr: 4.836 ± 2.418
2.901ValVal: 2.901 ± 0.522
0.0ValTrp: 0.0 ± 0.0
3.868ValTyr: 3.868 ± 2.011
0.0ValXaa: 0.0 ± 0.0
Trp
2.901TrpAla: 2.901 ± 0.522
0.0TrpCys: 0.0 ± 0.0
0.0TrpAsp: 0.0 ± 0.0
0.0TrpGlu: 0.0 ± 0.0
0.0TrpPhe: 0.0 ± 0.0
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
1.934TrpIle: 1.934 ± 0.967
0.967TrpLys: 0.967 ± 1.489
0.967TrpLeu: 0.967 ± 0.484
1.934TrpMet: 1.934 ± 2.978
0.0TrpAsn: 0.0 ± 0.0
0.967TrpPro: 0.967 ± 0.484
0.967TrpGln: 0.967 ± 0.484
0.0TrpArg: 0.0 ± 0.0
1.934TrpSer: 1.934 ± 2.978
0.967TrpThr: 0.967 ± 1.489
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
5.803TyrAla: 5.803 ± 1.043
0.967TyrCys: 0.967 ± 0.484
1.934TyrAsp: 1.934 ± 1.005
0.967TyrGlu: 0.967 ± 0.484
1.934TyrPhe: 1.934 ± 0.967
0.0TyrGly: 0.0 ± 0.0
0.0TyrHis: 0.0 ± 0.0
0.967TyrIle: 0.967 ± 0.484
0.0TyrLys: 0.0 ± 0.0
5.803TyrLeu: 5.803 ± 3.016
0.967TyrMet: 0.967 ± 2.241
1.934TyrAsn: 1.934 ± 1.005
0.0TyrPro: 0.0 ± 0.0
0.967TyrGln: 0.967 ± 1.489
1.934TyrArg: 1.934 ± 0.967
0.967TyrSer: 0.967 ± 0.484
0.0TyrThr: 0.0 ± 0.0
1.934TyrVal: 1.934 ± 0.967
0.0TyrTrp: 0.0 ± 0.0
0.967TyrTyr: 0.967 ± 0.484
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (1035 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski