Amino acid dipepetide frequency for Hubei permutotetra-like virus 11

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
1.318AlaAla: 1.318 ± 0.677
1.318AlaCys: 1.318 ± 0.677
3.296AlaAsp: 3.296 ± 0.486
1.318AlaGlu: 1.318 ± 0.677
3.296AlaPhe: 3.296 ± 0.486
3.296AlaGly: 3.296 ± 0.486
2.637AlaHis: 2.637 ± 1.059
1.318AlaIle: 1.318 ± 0.677
3.296AlaLys: 3.296 ± 1.927
1.318AlaLeu: 1.318 ± 0.677
0.659AlaMet: 0.659 ± 0.868
1.318AlaAsn: 1.318 ± 0.53
4.614AlaPro: 4.614 ± 0.044
0.659AlaGln: 0.659 ± 0.868
4.614AlaArg: 4.614 ± 0.044
5.933AlaSer: 5.933 ± 2.987
1.978AlaThr: 1.978 ± 1.015
5.933AlaVal: 5.933 ± 4.193
0.659AlaTrp: 0.659 ± 0.338
1.318AlaTyr: 1.318 ± 0.53
0.0AlaXaa: 0.0 ± 0.0
Cys
0.659CysAla: 0.659 ± 0.338
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
2.637CysGlu: 2.637 ± 0.147
0.0CysPhe: 0.0 ± 0.0
1.318CysGly: 1.318 ± 1.736
0.0CysHis: 0.0 ± 0.0
1.978CysIle: 1.978 ± 1.015
0.659CysLys: 0.659 ± 0.868
1.318CysLeu: 1.318 ± 0.677
0.659CysMet: 0.659 ± 0.338
0.0CysAsn: 0.0 ± 0.0
0.659CysPro: 0.659 ± 0.338
0.0CysGln: 0.0 ± 0.0
0.659CysArg: 0.659 ± 0.868
0.659CysSer: 0.659 ± 0.338
0.0CysThr: 0.0 ± 0.0
0.659CysVal: 0.659 ± 0.338
0.0CysTrp: 0.0 ± 0.0
0.659CysTyr: 0.659 ± 0.338
0.0CysXaa: 0.0 ± 0.0
Asp
5.274AspAla: 5.274 ± 0.294
0.659AspCys: 0.659 ± 0.338
5.933AspAsp: 5.933 ± 1.839
3.296AspGlu: 3.296 ± 1.692
1.318AspPhe: 1.318 ± 0.677
1.978AspGly: 1.978 ± 1.015
1.318AspHis: 1.318 ± 0.677
6.592AspIle: 6.592 ± 0.971
5.933AspLys: 5.933 ± 1.839
5.274AspLeu: 5.274 ± 0.912
0.659AspMet: 0.659 ± 0.338
0.659AspAsn: 0.659 ± 0.338
4.614AspPro: 4.614 ± 1.251
0.659AspGln: 0.659 ± 0.338
5.933AspArg: 5.933 ± 0.633
1.978AspSer: 1.978 ± 0.191
2.637AspThr: 2.637 ± 1.059
3.955AspVal: 3.955 ± 0.383
0.659AspTrp: 0.659 ± 0.338
0.0AspTyr: 0.0 ± 0.0
0.0AspXaa: 0.0 ± 0.0
Glu
3.296GluAla: 3.296 ± 1.692
2.637GluCys: 2.637 ± 0.147
5.274GluAsp: 5.274 ± 0.294
2.637GluGlu: 2.637 ± 0.147
1.318GluPhe: 1.318 ± 0.677
3.296GluGly: 3.296 ± 0.721
0.659GluHis: 0.659 ± 0.338
1.978GluIle: 1.978 ± 0.191
5.933GluLys: 5.933 ± 0.633
5.274GluLeu: 5.274 ± 0.294
2.637GluMet: 2.637 ± 1.354
3.296GluAsn: 3.296 ± 0.721
0.659GluPro: 0.659 ± 0.338
1.978GluGln: 1.978 ± 0.191
1.978GluArg: 1.978 ± 1.015
3.955GluSer: 3.955 ± 0.824
3.955GluThr: 3.955 ± 4.002
4.614GluVal: 4.614 ± 2.369
0.659GluTrp: 0.659 ± 0.338
1.978GluTyr: 1.978 ± 1.398
0.0GluXaa: 0.0 ± 0.0
Phe
0.0PheAla: 0.0 ± 0.0
0.659PheCys: 0.659 ± 0.338
3.955PheAsp: 3.955 ± 0.383
1.318PheGlu: 1.318 ± 0.677
0.0PhePhe: 0.0 ± 0.0
0.659PheGly: 0.659 ± 0.338
0.0PheHis: 0.0 ± 0.0
1.318PheIle: 1.318 ± 0.53
3.955PheLys: 3.955 ± 0.824
4.614PheLeu: 4.614 ± 0.044
2.637PheMet: 2.637 ± 2.266
2.637PheAsn: 2.637 ± 1.354
1.318PhePro: 1.318 ± 0.677
0.659PheGln: 0.659 ± 0.338
0.659PheArg: 0.659 ± 0.868
1.978PheSer: 1.978 ± 1.015
1.318PheThr: 1.318 ± 0.53
3.296PheVal: 3.296 ± 0.486
1.318PheTrp: 1.318 ± 0.53
1.318PheTyr: 1.318 ± 0.53
0.0PheXaa: 0.0 ± 0.0
Gly
1.978GlyAla: 1.978 ± 1.398
0.0GlyCys: 0.0 ± 0.0
5.274GlyAsp: 5.274 ± 0.294
3.296GlyGlu: 3.296 ± 1.927
4.614GlyPhe: 4.614 ± 0.044
3.955GlyGly: 3.955 ± 1.589
0.0GlyHis: 0.0 ± 0.0
3.296GlyIle: 3.296 ± 1.692
4.614GlyLys: 4.614 ± 1.162
6.592GlyLeu: 6.592 ± 2.177
0.659GlyMet: 0.659 ± 0.868
1.318GlyAsn: 1.318 ± 0.53
0.0GlyPro: 0.0 ± 0.0
1.978GlyGln: 1.978 ± 0.191
2.637GlyArg: 2.637 ± 1.059
3.296GlySer: 3.296 ± 1.927
5.933GlyThr: 5.933 ± 0.574
7.251GlyVal: 7.251 ± 3.722
1.318GlyTrp: 1.318 ± 0.677
3.955GlyTyr: 3.955 ± 0.383
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
0.0HisCys: 0.0 ± 0.0
0.659HisAsp: 0.659 ± 0.338
0.0HisGlu: 0.0 ± 0.0
1.318HisPhe: 1.318 ± 0.53
0.659HisGly: 0.659 ± 0.338
0.659HisHis: 0.659 ± 0.338
0.659HisIle: 0.659 ± 0.338
1.318HisLys: 1.318 ± 0.53
0.659HisLeu: 0.659 ± 0.338
0.0HisMet: 0.0 ± 0.0
1.978HisAsn: 1.978 ± 0.191
1.318HisPro: 1.318 ± 0.677
1.318HisGln: 1.318 ± 0.53
0.0HisArg: 0.0 ± 0.0
0.659HisSer: 0.659 ± 0.338
0.659HisThr: 0.659 ± 0.868
1.318HisVal: 1.318 ± 0.53
1.318HisTrp: 1.318 ± 0.677
0.659HisTyr: 0.659 ± 0.868
0.0HisXaa: 0.0 ± 0.0
Ile
2.637IleAla: 2.637 ± 2.266
0.659IleCys: 0.659 ± 0.338
3.296IleAsp: 3.296 ± 1.692
2.637IleGlu: 2.637 ± 0.147
1.978IlePhe: 1.978 ± 1.015
1.318IleGly: 1.318 ± 0.53
0.659IleHis: 0.659 ± 0.338
3.296IleIle: 3.296 ± 0.721
4.614IleLys: 4.614 ± 1.162
5.274IleLeu: 5.274 ± 1.501
0.0IleMet: 0.0 ± 0.0
2.637IleAsn: 2.637 ± 1.059
5.274IlePro: 5.274 ± 1.501
3.296IleGln: 3.296 ± 0.486
0.659IleArg: 0.659 ± 0.338
3.955IleSer: 3.955 ± 1.589
1.978IleThr: 1.978 ± 1.015
5.274IleVal: 5.274 ± 0.912
0.659IleTrp: 0.659 ± 0.338
0.659IleTyr: 0.659 ± 0.338
0.0IleXaa: 0.0 ± 0.0
Lys
3.296LysAla: 3.296 ± 0.486
0.0LysCys: 0.0 ± 0.0
3.955LysAsp: 3.955 ± 0.824
3.296LysGlu: 3.296 ± 1.692
4.614LysPhe: 4.614 ± 0.044
1.978LysGly: 1.978 ± 1.015
0.659LysHis: 0.659 ± 0.338
5.933LysIle: 5.933 ± 0.633
6.592LysLys: 6.592 ± 1.442
9.229LysLeu: 9.229 ± 1.295
1.318LysMet: 1.318 ± 1.736
1.978LysAsn: 1.978 ± 0.191
5.933LysPro: 5.933 ± 0.633
3.296LysGln: 3.296 ± 0.486
3.955LysArg: 3.955 ± 0.824
3.955LysSer: 3.955 ± 0.383
7.251LysThr: 7.251 ± 1.309
5.933LysVal: 5.933 ± 3.046
1.978LysTrp: 1.978 ± 0.191
2.637LysTyr: 2.637 ± 0.147
0.0LysXaa: 0.0 ± 0.0
Leu
1.978LeuAla: 1.978 ± 1.015
0.659LeuCys: 0.659 ± 0.338
5.933LeuAsp: 5.933 ± 3.046
7.251LeuGlu: 7.251 ± 2.31
5.933LeuPhe: 5.933 ± 0.633
5.274LeuGly: 5.274 ± 2.707
0.659LeuHis: 0.659 ± 0.338
1.318LeuIle: 1.318 ± 0.677
4.614LeuLys: 4.614 ± 1.251
7.251LeuLeu: 7.251 ± 1.103
4.614LeuMet: 4.614 ± 0.457
5.933LeuAsn: 5.933 ± 3.046
4.614LeuPro: 4.614 ± 0.044
3.955LeuGln: 3.955 ± 2.03
5.274LeuArg: 5.274 ± 2.119
3.955LeuSer: 3.955 ± 2.795
5.933LeuThr: 5.933 ± 0.574
5.274LeuVal: 5.274 ± 0.912
0.0LeuTrp: 0.0 ± 0.0
2.637LeuTyr: 2.637 ± 1.059
0.0LeuXaa: 0.0 ± 0.0
Met
1.318MetAla: 1.318 ± 0.53
0.0MetCys: 0.0 ± 0.0
1.318MetAsp: 1.318 ± 0.677
3.296MetGlu: 3.296 ± 0.486
0.659MetPhe: 0.659 ± 0.338
2.637MetGly: 2.637 ± 1.354
0.0MetHis: 0.0 ± 0.0
2.637MetIle: 2.637 ± 2.266
1.318MetLys: 1.318 ± 0.53
2.637MetLeu: 2.637 ± 1.354
0.0MetMet: 0.0 ± 0.0
1.318MetAsn: 1.318 ± 0.677
1.978MetPro: 1.978 ± 1.398
1.318MetGln: 1.318 ± 0.53
0.659MetArg: 0.659 ± 0.338
1.978MetSer: 1.978 ± 1.398
1.978MetThr: 1.978 ± 0.191
4.614MetVal: 4.614 ± 0.044
0.659MetTrp: 0.659 ± 0.868
0.659MetTyr: 0.659 ± 0.338
0.0MetXaa: 0.0 ± 0.0
Asn
1.978AsnAla: 1.978 ± 0.191
0.659AsnCys: 0.659 ± 0.338
0.0AsnAsp: 0.0 ± 0.0
1.978AsnGlu: 1.978 ± 0.191
0.659AsnPhe: 0.659 ± 0.338
3.955AsnGly: 3.955 ± 0.383
0.659AsnHis: 0.659 ± 0.338
1.978AsnIle: 1.978 ± 0.191
4.614AsnLys: 4.614 ± 2.369
5.933AsnLeu: 5.933 ± 2.987
0.659AsnMet: 0.659 ± 0.338
1.318AsnAsn: 1.318 ± 0.53
4.614AsnPro: 4.614 ± 1.162
2.637AsnGln: 2.637 ± 0.147
1.318AsnArg: 1.318 ± 0.677
5.933AsnSer: 5.933 ± 0.574
1.978AsnThr: 1.978 ± 1.015
2.637AsnVal: 2.637 ± 0.147
1.978AsnTrp: 1.978 ± 1.015
2.637AsnTyr: 2.637 ± 1.059
0.0AsnXaa: 0.0 ± 0.0
Pro
4.614ProAla: 4.614 ± 2.457
0.659ProCys: 0.659 ± 0.868
3.296ProAsp: 3.296 ± 1.692
2.637ProGlu: 2.637 ± 1.354
0.659ProPhe: 0.659 ± 0.338
3.955ProGly: 3.955 ± 2.795
0.0ProHis: 0.0 ± 0.0
1.318ProIle: 1.318 ± 0.677
2.637ProLys: 2.637 ± 0.147
3.955ProLeu: 3.955 ± 0.824
0.0ProMet: 0.0 ± 0.294
3.955ProAsn: 3.955 ± 0.383
3.296ProPro: 3.296 ± 0.721
2.637ProGln: 2.637 ± 1.059
3.296ProArg: 3.296 ± 0.721
7.251ProSer: 7.251 ± 1.103
5.274ProThr: 5.274 ± 0.912
4.614ProVal: 4.614 ± 2.369
1.318ProTrp: 1.318 ± 0.677
2.637ProTyr: 2.637 ± 1.354
0.0ProXaa: 0.0 ± 0.0
Gln
1.318GlnAla: 1.318 ± 1.736
0.0GlnCys: 0.0 ± 0.0
3.296GlnAsp: 3.296 ± 0.486
5.933GlnGlu: 5.933 ± 1.839
0.659GlnPhe: 0.659 ± 0.338
3.296GlnGly: 3.296 ± 0.721
0.659GlnHis: 0.659 ± 0.868
1.978GlnIle: 1.978 ± 1.015
3.296GlnLys: 3.296 ± 0.721
3.296GlnLeu: 3.296 ± 0.486
1.978GlnMet: 1.978 ± 1.015
1.978GlnAsn: 1.978 ± 0.191
0.659GlnPro: 0.659 ± 0.868
0.659GlnGln: 0.659 ± 0.338
1.978GlnArg: 1.978 ± 0.191
2.637GlnSer: 2.637 ± 1.354
1.318GlnThr: 1.318 ± 1.736
1.978GlnVal: 1.978 ± 1.015
0.0GlnTrp: 0.0 ± 0.0
1.318GlnTyr: 1.318 ± 0.677
0.0GlnXaa: 0.0 ± 0.0
Arg
3.296ArgAla: 3.296 ± 1.927
0.0ArgCys: 0.0 ± 0.0
1.318ArgAsp: 1.318 ± 1.736
2.637ArgGlu: 2.637 ± 0.147
0.0ArgPhe: 0.0 ± 0.0
3.296ArgGly: 3.296 ± 0.721
0.659ArgHis: 0.659 ± 0.338
3.955ArgIle: 3.955 ± 0.383
7.251ArgLys: 7.251 ± 2.516
3.955ArgLeu: 3.955 ± 1.589
1.318ArgMet: 1.318 ± 0.677
1.978ArgAsn: 1.978 ± 1.015
2.637ArgPro: 2.637 ± 1.354
2.637ArgGln: 2.637 ± 1.354
5.274ArgArg: 5.274 ± 1.501
2.637ArgSer: 2.637 ± 1.354
3.955ArgThr: 3.955 ± 1.589
1.978ArgVal: 1.978 ± 1.398
0.0ArgTrp: 0.0 ± 0.0
1.318ArgTyr: 1.318 ± 0.53
0.0ArgXaa: 0.0 ± 0.0
Ser
6.592SerAla: 6.592 ± 2.648
0.659SerCys: 0.659 ± 0.868
3.296SerAsp: 3.296 ± 0.721
2.637SerGlu: 2.637 ± 2.266
1.318SerPhe: 1.318 ± 1.736
7.251SerGly: 7.251 ± 1.309
1.318SerHis: 1.318 ± 0.53
1.318SerIle: 1.318 ± 0.53
3.955SerLys: 3.955 ± 0.383
7.251SerLeu: 7.251 ± 2.516
2.637SerMet: 2.637 ± 2.266
6.592SerAsn: 6.592 ± 0.235
2.637SerPro: 2.637 ± 2.266
3.296SerGln: 3.296 ± 0.721
1.978SerArg: 1.978 ± 0.191
11.866SerSer: 11.866 ± 0.059
4.614SerThr: 4.614 ± 0.044
6.592SerVal: 6.592 ± 0.235
0.0SerTrp: 0.0 ± 0.0
0.659SerTyr: 0.659 ± 0.338
0.0SerXaa: 0.0 ± 0.0
Thr
3.296ThrAla: 3.296 ± 0.721
0.659ThrCys: 0.659 ± 0.338
1.978ThrAsp: 1.978 ± 1.398
1.978ThrGlu: 1.978 ± 1.015
3.296ThrPhe: 3.296 ± 0.721
5.274ThrGly: 5.274 ± 0.912
1.318ThrHis: 1.318 ± 0.677
3.296ThrIle: 3.296 ± 1.927
5.933ThrLys: 5.933 ± 0.633
5.933ThrLeu: 5.933 ± 1.78
3.955ThrMet: 3.955 ± 0.383
3.955ThrAsn: 3.955 ± 0.383
4.614ThrPro: 4.614 ± 1.251
1.318ThrGln: 1.318 ± 0.677
2.637ThrArg: 2.637 ± 1.059
3.955ThrSer: 3.955 ± 2.795
6.592ThrThr: 6.592 ± 0.235
3.955ThrVal: 3.955 ± 0.824
1.318ThrTrp: 1.318 ± 0.677
1.318ThrTyr: 1.318 ± 0.677
0.0ThrXaa: 0.0 ± 0.0
Val
3.955ValAla: 3.955 ± 0.824
2.637ValCys: 2.637 ± 0.147
4.614ValAsp: 4.614 ± 0.044
6.592ValGlu: 6.592 ± 0.235
1.318ValPhe: 1.318 ± 0.53
5.933ValGly: 5.933 ± 0.574
1.978ValHis: 1.978 ± 0.191
4.614ValIle: 4.614 ± 2.369
5.933ValLys: 5.933 ± 1.839
2.637ValLeu: 2.637 ± 0.147
1.978ValMet: 1.978 ± 1.015
3.296ValAsn: 3.296 ± 1.692
7.251ValPro: 7.251 ± 1.103
2.637ValGln: 2.637 ± 1.354
2.637ValArg: 2.637 ± 0.147
5.933ValSer: 5.933 ± 0.633
4.614ValThr: 4.614 ± 1.251
6.592ValVal: 6.592 ± 1.442
1.978ValTrp: 1.978 ± 0.191
3.955ValTyr: 3.955 ± 0.383
0.0ValXaa: 0.0 ± 0.0
Trp
1.978TrpAla: 1.978 ± 1.015
0.0TrpCys: 0.0 ± 0.0
0.659TrpAsp: 0.659 ± 0.868
0.0TrpGlu: 0.0 ± 0.0
0.0TrpPhe: 0.0 ± 0.0
0.659TrpGly: 0.659 ± 0.338
0.0TrpHis: 0.0 ± 0.0
1.318TrpIle: 1.318 ± 0.53
1.318TrpLys: 1.318 ± 0.677
0.0TrpLeu: 0.0 ± 0.0
1.318TrpMet: 1.318 ± 0.677
1.318TrpAsn: 1.318 ± 0.53
1.318TrpPro: 1.318 ± 0.677
0.659TrpGln: 0.659 ± 0.868
1.318TrpArg: 1.318 ± 0.677
1.978TrpSer: 1.978 ± 1.015
1.318TrpThr: 1.318 ± 0.677
1.318TrpVal: 1.318 ± 0.677
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.318TyrAla: 1.318 ± 0.677
0.659TyrCys: 0.659 ± 0.868
1.978TyrAsp: 1.978 ± 1.015
2.637TyrGlu: 2.637 ± 0.147
0.659TyrPhe: 0.659 ± 0.868
1.978TyrGly: 1.978 ± 1.015
1.318TyrHis: 1.318 ± 1.736
0.659TyrIle: 0.659 ± 0.338
0.0TyrLys: 0.0 ± 0.0
0.659TyrLeu: 0.659 ± 0.338
2.637TyrMet: 2.637 ± 0.147
0.659TyrAsn: 0.659 ± 0.868
0.659TyrPro: 0.659 ± 0.338
2.637TyrGln: 2.637 ± 1.059
2.637TyrArg: 2.637 ± 1.354
1.978TyrSer: 1.978 ± 2.604
3.296TyrThr: 3.296 ± 0.486
3.296TyrVal: 3.296 ± 0.721
0.659TyrTrp: 0.659 ± 0.338
1.318TyrTyr: 1.318 ± 0.53
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (1518 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski