Amino acid dipepetide frequency for Otolemur garnettii (Small-eared galago) (Garnett s greater bushbaby)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.602AlaAla: 6.602 ± 0.046
1.438AlaCys: 1.438 ± 0.015
2.832AlaAsp: 2.832 ± 0.018
4.608AlaGlu: 4.608 ± 0.029
2.802AlaPhe: 2.802 ± 0.021
4.657AlaGly: 4.657 ± 0.033
1.587AlaHis: 1.587 ± 0.012
2.833AlaIle: 2.833 ± 0.017
3.365AlaLys: 3.365 ± 0.025
7.237AlaLeu: 7.237 ± 0.037
1.51AlaMet: 1.51 ± 0.012
1.975AlaAsn: 1.975 ± 0.016
4.058AlaPro: 4.058 ± 0.032
3.189AlaGln: 3.189 ± 0.023
3.582AlaArg: 3.582 ± 0.025
5.624AlaSer: 5.624 ± 0.03
3.554AlaThr: 3.554 ± 0.022
4.699AlaVal: 4.699 ± 0.027
0.806AlaTrp: 0.806 ± 0.009
1.57AlaTyr: 1.57 ± 0.014
0.002AlaXaa: 0.002 ± 0.0
Cys
1.318CysAla: 1.318 ± 0.015
0.687CysCys: 0.687 ± 0.016
1.056CysAsp: 1.056 ± 0.015
1.305CysGlu: 1.305 ± 0.016
0.894CysPhe: 0.894 ± 0.011
1.933CysGly: 1.933 ± 0.03
0.691CysHis: 0.691 ± 0.01
0.967CysIle: 0.967 ± 0.011
1.198CysLys: 1.198 ± 0.016
2.231CysLeu: 2.231 ± 0.019
0.423CysMet: 0.423 ± 0.006
0.847CysAsn: 0.847 ± 0.012
1.424CysPro: 1.424 ± 0.018
1.138CysGln: 1.138 ± 0.015
1.309CysArg: 1.309 ± 0.015
2.084CysSer: 2.084 ± 0.023
1.135CysThr: 1.135 ± 0.013
1.347CysVal: 1.347 ± 0.014
0.302CysTrp: 0.302 ± 0.006
0.616CysTyr: 0.616 ± 0.009
0.001CysXaa: 0.001 ± 0.0
Asp
2.755AspAla: 2.755 ± 0.02
1.064AspCys: 1.064 ± 0.015
2.546AspAsp: 2.546 ± 0.022
3.301AspGlu: 3.301 ± 0.024
2.121AspPhe: 2.121 ± 0.013
3.178AspGly: 3.178 ± 0.025
1.129AspHis: 1.129 ± 0.011
2.583AspIle: 2.583 ± 0.017
2.485AspLys: 2.485 ± 0.017
4.934AspLeu: 4.934 ± 0.026
1.094AspMet: 1.094 ± 0.011
1.672AspAsn: 1.672 ± 0.015
2.861AspPro: 2.861 ± 0.015
1.799AspGln: 1.799 ± 0.013
2.419AspArg: 2.419 ± 0.019
4.127AspSer: 4.127 ± 0.03
2.454AspThr: 2.454 ± 0.017
3.035AspVal: 3.035 ± 0.021
0.622AspTrp: 0.622 ± 0.009
1.453AspTyr: 1.453 ± 0.013
0.001AspXaa: 0.001 ± 0.0
Glu
5.117GluAla: 5.117 ± 0.031
1.576GluCys: 1.576 ± 0.031
4.324GluAsp: 4.324 ± 0.026
7.735GluGlu: 7.735 ± 0.058
2.063GluPhe: 2.063 ± 0.016
4.116GluGly: 4.116 ± 0.024
1.495GluHis: 1.495 ± 0.014
3.121GluIle: 3.121 ± 0.024
5.404GluLys: 5.404 ± 0.044
6.338GluLeu: 6.338 ± 0.041
1.618GluMet: 1.618 ± 0.015
3.04GluAsn: 3.04 ± 0.022
3.185GluPro: 3.185 ± 0.024
3.055GluGln: 3.055 ± 0.025
3.864GluArg: 3.864 ± 0.03
4.22GluSer: 4.22 ± 0.026
3.299GluThr: 3.299 ± 0.02
4.125GluVal: 4.125 ± 0.025
0.695GluTrp: 0.695 ± 0.009
1.548GluTyr: 1.548 ± 0.014
0.001GluXaa: 0.001 ± 0.0
Phe
1.997PheAla: 1.997 ± 0.015
1.025PheCys: 1.025 ± 0.01
1.671PheAsp: 1.671 ± 0.016
1.987PheGlu: 1.987 ± 0.016
1.784PhePhe: 1.784 ± 0.016
2.268PheGly: 2.268 ± 0.021
1.071PheHis: 1.071 ± 0.011
1.945PheIle: 1.945 ± 0.016
1.818PheLys: 1.818 ± 0.015
4.41PheLeu: 4.41 ± 0.028
0.788PheMet: 0.788 ± 0.008
1.405PheAsn: 1.405 ± 0.014
2.073PhePro: 2.073 ± 0.016
1.841PheGln: 1.841 ± 0.013
1.975PheArg: 1.975 ± 0.016
3.619PheSer: 3.619 ± 0.024
2.105PheThr: 2.105 ± 0.018
2.231PheVal: 2.231 ± 0.016
0.518PheTrp: 0.518 ± 0.008
1.281PheTyr: 1.281 ± 0.013
0.001PheXaa: 0.001 ± 0.0
Gly
4.486GlyAla: 4.486 ± 0.034
1.318GlyCys: 1.318 ± 0.014
3.078GlyAsp: 3.078 ± 0.025
4.237GlyGlu: 4.237 ± 0.034
2.474GlyPhe: 2.474 ± 0.023
4.966GlyGly: 4.966 ± 0.047
1.725GlyHis: 1.725 ± 0.016
2.78GlyIle: 2.78 ± 0.022
3.93GlyLys: 3.93 ± 0.03
6.079GlyLeu: 6.079 ± 0.042
1.279GlyMet: 1.279 ± 0.013
2.386GlyAsn: 2.386 ± 0.017
4.276GlyPro: 4.276 ± 0.07
2.779GlyGln: 2.779 ± 0.025
3.685GlyArg: 3.685 ± 0.028
5.741GlySer: 5.741 ± 0.037
3.585GlyThr: 3.585 ± 0.024
3.546GlyVal: 3.546 ± 0.022
0.798GlyTrp: 0.798 ± 0.01
1.747GlyTyr: 1.747 ± 0.017
0.002GlyXaa: 0.002 ± 0.0
His
1.302HisAla: 1.302 ± 0.012
0.75HisCys: 0.75 ± 0.011
0.853HisAsp: 0.853 ± 0.009
1.303HisGlu: 1.303 ± 0.013
1.153HisPhe: 1.153 ± 0.011
1.548HisGly: 1.548 ± 0.012
0.915HisHis: 0.915 ± 0.014
1.278HisIle: 1.278 ± 0.012
1.299HisLys: 1.299 ± 0.012
3.049HisLeu: 3.049 ± 0.023
0.597HisMet: 0.597 ± 0.008
0.867HisAsn: 0.867 ± 0.011
1.643HisPro: 1.643 ± 0.016
1.457HisGln: 1.457 ± 0.02
1.618HisArg: 1.618 ± 0.014
2.386HisSer: 2.386 ± 0.021
1.658HisThr: 1.658 ± 0.023
1.501HisVal: 1.501 ± 0.013
0.369HisTrp: 0.369 ± 0.007
0.842HisTyr: 0.842 ± 0.01
0.001HisXaa: 0.001 ± 0.0
Ile
2.554IleAla: 2.554 ± 0.018
1.139IleCys: 1.139 ± 0.014
1.966IleAsp: 1.966 ± 0.016
2.507IleGlu: 2.507 ± 0.02
2.012IlePhe: 2.012 ± 0.019
2.201IleGly: 2.201 ± 0.017
1.535IleHis: 1.535 ± 0.024
2.456IleIle: 2.456 ± 0.021
2.578IleLys: 2.578 ± 0.019
4.797IleLeu: 4.797 ± 0.023
0.989IleMet: 0.989 ± 0.011
1.808IleAsn: 1.808 ± 0.016
2.637IlePro: 2.637 ± 0.018
2.26IleGln: 2.26 ± 0.017
2.352IleArg: 2.352 ± 0.015
3.751IleSer: 3.751 ± 0.021
2.557IleThr: 2.557 ± 0.019
2.533IleVal: 2.533 ± 0.017
0.523IleTrp: 0.523 ± 0.007
1.478IleTyr: 1.478 ± 0.013
0.0IleXaa: 0.0 ± 0.0
Lys
4.077LysAla: 4.077 ± 0.031
1.267LysCys: 1.267 ± 0.022
3.065LysAsp: 3.065 ± 0.021
5.056LysGlu: 5.056 ± 0.04
1.747LysPhe: 1.747 ± 0.013
3.269LysGly: 3.269 ± 0.031
1.411LysHis: 1.411 ± 0.013
2.782LysIle: 2.782 ± 0.022
4.81LysLys: 4.81 ± 0.041
5.127LysLeu: 5.127 ± 0.028
1.459LysMet: 1.459 ± 0.014
2.4LysAsn: 2.4 ± 0.018
3.182LysPro: 3.182 ± 0.028
2.56LysGln: 2.56 ± 0.02
3.25LysArg: 3.25 ± 0.024
3.875LysSer: 3.875 ± 0.026
3.105LysThr: 3.105 ± 0.02
3.466LysVal: 3.466 ± 0.018
0.599LysTrp: 0.599 ± 0.007
1.577LysTyr: 1.577 ± 0.016
0.001LysXaa: 0.001 ± 0.0
Leu
6.988LeuAla: 6.988 ± 0.035
2.282LeuCys: 2.282 ± 0.019
4.731LeuAsp: 4.731 ± 0.025
7.058LeuGlu: 7.058 ± 0.049
3.561LeuPhe: 3.561 ± 0.025
6.154LeuGly: 6.154 ± 0.033
2.784LeuHis: 2.784 ± 0.017
4.041LeuIle: 4.041 ± 0.027
5.753LeuLys: 5.753 ± 0.035
11.173LeuLeu: 11.173 ± 0.062
2.007LeuMet: 2.007 ± 0.013
3.544LeuAsn: 3.544 ± 0.022
6.068LeuPro: 6.068 ± 0.032
5.766LeuGln: 5.766 ± 0.039
5.986LeuArg: 5.986 ± 0.034
8.239LeuSer: 8.239 ± 0.036
5.208LeuThr: 5.208 ± 0.025
5.725LeuVal: 5.725 ± 0.027
1.18LeuTrp: 1.18 ± 0.013
2.643LeuTyr: 2.643 ± 0.019
0.002LeuXaa: 0.002 ± 0.001
Met
1.944MetAla: 1.944 ± 0.014
0.398MetCys: 0.398 ± 0.006
1.212MetAsp: 1.212 ± 0.011
1.783MetGlu: 1.783 ± 0.014
0.751MetPhe: 0.751 ± 0.009
1.291MetGly: 1.291 ± 0.013
0.448MetHis: 0.448 ± 0.007
0.841MetIle: 0.841 ± 0.01
1.434MetLys: 1.434 ± 0.012
2.001MetLeu: 2.001 ± 0.015
0.531MetMet: 0.531 ± 0.008
0.879MetAsn: 0.879 ± 0.01
1.071MetPro: 1.071 ± 0.013
0.884MetGln: 0.884 ± 0.009
1.016MetArg: 1.016 ± 0.011
1.547MetSer: 1.547 ± 0.013
1.087MetThr: 1.087 ± 0.009
1.392MetVal: 1.392 ± 0.014
0.246MetTrp: 0.246 ± 0.005
0.639MetTyr: 0.639 ± 0.008
0.001MetXaa: 0.001 ± 0.0
Asn
1.97AsnAla: 1.97 ± 0.015
0.861AsnCys: 0.861 ± 0.011
1.462AsnAsp: 1.462 ± 0.015
2.167AsnGlu: 2.167 ± 0.016
1.535AsnPhe: 1.535 ± 0.014
2.36AsnGly: 2.36 ± 0.022
0.965AsnHis: 0.965 ± 0.009
2.096AsnIle: 2.096 ± 0.017
2.22AsnLys: 2.22 ± 0.018
3.801AsnLeu: 3.801 ± 0.026
0.889AsnMet: 0.889 ± 0.011
1.517AsnAsn: 1.517 ± 0.014
2.219AsnPro: 2.219 ± 0.015
1.633AsnGln: 1.633 ± 0.017
1.818AsnArg: 1.818 ± 0.015
3.103AsnSer: 3.103 ± 0.019
1.932AsnThr: 1.932 ± 0.014
2.188AsnVal: 2.188 ± 0.016
0.458AsnTrp: 0.458 ± 0.007
1.132AsnTyr: 1.132 ± 0.012
0.001AsnXaa: 0.001 ± 0.0
Pro
4.68ProAla: 4.68 ± 0.033
1.175ProCys: 1.175 ± 0.016
2.768ProAsp: 2.768 ± 0.021
4.379ProGlu: 4.379 ± 0.026
1.988ProPhe: 1.988 ± 0.017
5.271ProGly: 5.271 ± 0.099
1.444ProHis: 1.444 ± 0.013
1.875ProIle: 1.875 ± 0.016
2.788ProLys: 2.788 ± 0.025
5.323ProLeu: 5.323 ± 0.028
1.088ProMet: 1.088 ± 0.011
1.792ProAsn: 1.792 ± 0.016
5.855ProPro: 5.855 ± 0.072
2.829ProGln: 2.829 ± 0.022
3.306ProArg: 3.306 ± 0.023
5.561ProSer: 5.561 ± 0.04
3.061ProThr: 3.061 ± 0.022
3.744ProVal: 3.744 ± 0.023
0.714ProTrp: 0.714 ± 0.01
1.642ProTyr: 1.642 ± 0.022
0.002ProXaa: 0.002 ± 0.0
Gln
3.467GlnAla: 3.467 ± 0.022
0.973GlnCys: 0.973 ± 0.014
2.313GlnAsp: 2.313 ± 0.016
3.877GlnGlu: 3.877 ± 0.03
1.359GlnPhe: 1.359 ± 0.013
2.881GlnGly: 2.881 ± 0.026
1.328GlnHis: 1.328 ± 0.014
1.959GlnIle: 1.959 ± 0.017
2.959GlnLys: 2.959 ± 0.021
4.772GlnLeu: 4.772 ± 0.031
1.081GlnMet: 1.081 ± 0.012
1.843GlnAsn: 1.843 ± 0.014
2.743GlnPro: 2.743 ± 0.025
2.934GlnGln: 2.934 ± 0.04
3.01GlnArg: 3.01 ± 0.023
3.081GlnSer: 3.081 ± 0.021
2.286GlnThr: 2.286 ± 0.016
2.844GlnVal: 2.844 ± 0.019
0.538GlnTrp: 0.538 ± 0.008
1.144GlnTyr: 1.144 ± 0.012
0.002GlnXaa: 0.002 ± 0.0
Arg
3.828ArgAla: 3.828 ± 0.025
1.217ArgCys: 1.217 ± 0.018
2.706ArgAsp: 2.706 ± 0.02
3.892ArgGlu: 3.892 ± 0.026
1.867ArgPhe: 1.867 ± 0.015
3.555ArgGly: 3.555 ± 0.034
1.561ArgHis: 1.561 ± 0.015
2.485ArgIle: 2.485 ± 0.022
3.667ArgLys: 3.667 ± 0.023
5.369ArgLeu: 5.369 ± 0.029
1.135ArgMet: 1.135 ± 0.012
2.113ArgAsn: 2.113 ± 0.015
3.155ArgPro: 3.155 ± 0.024
2.573ArgGln: 2.573 ± 0.017
4.223ArgArg: 4.223 ± 0.031
4.109ArgSer: 4.109 ± 0.033
2.779ArgThr: 2.779 ± 0.02
3.164ArgVal: 3.164 ± 0.019
0.695ArgTrp: 0.695 ± 0.01
1.509ArgTyr: 1.509 ± 0.012
0.002ArgXaa: 0.002 ± 0.001
Ser
5.212SerAla: 5.212 ± 0.027
1.9SerCys: 1.9 ± 0.02
3.78SerAsp: 3.78 ± 0.025
5.039SerGlu: 5.039 ± 0.034
3.174SerPhe: 3.174 ± 0.022
5.699SerGly: 5.699 ± 0.039
2.219SerHis: 2.219 ± 0.019
3.235SerIle: 3.235 ± 0.018
4.01SerLys: 4.01 ± 0.028
8.377SerLeu: 8.377 ± 0.037
1.54SerMet: 1.54 ± 0.013
2.679SerAsn: 2.679 ± 0.018
5.842SerPro: 5.842 ± 0.046
3.854SerGln: 3.854 ± 0.025
4.456SerArg: 4.456 ± 0.029
9.127SerSer: 9.127 ± 0.062
4.401SerThr: 4.401 ± 0.029
4.909SerVal: 4.909 ± 0.024
1.084SerTrp: 1.084 ± 0.011
2.174SerTyr: 2.174 ± 0.017
0.003SerXaa: 0.003 ± 0.0
Thr
3.676ThrAla: 3.676 ± 0.022
1.371ThrCys: 1.371 ± 0.019
2.417ThrAsp: 2.417 ± 0.018
3.45ThrGlu: 3.45 ± 0.021
2.224ThrPhe: 2.224 ± 0.018
3.612ThrGly: 3.612 ± 0.029
1.363ThrHis: 1.363 ± 0.015
2.429ThrIle: 2.429 ± 0.019
2.648ThrLys: 2.648 ± 0.02
5.419ThrLeu: 5.419 ± 0.023
1.117ThrMet: 1.117 ± 0.01
1.702ThrAsn: 1.702 ± 0.014
3.479ThrPro: 3.479 ± 0.026
2.309ThrGln: 2.309 ± 0.017
2.418ThrArg: 2.418 ± 0.017
4.534ThrSer: 4.534 ± 0.032
2.96ThrThr: 2.96 ± 0.032
3.886ThrVal: 3.886 ± 0.026
0.694ThrTrp: 0.694 ± 0.01
1.45ThrTyr: 1.45 ± 0.013
0.002ThrXaa: 0.002 ± 0.0
Val
4.311ValAla: 4.311 ± 0.023
1.504ValCys: 1.504 ± 0.015
2.898ValAsp: 2.898 ± 0.018
3.728ValGlu: 3.728 ± 0.023
2.522ValPhe: 2.522 ± 0.02
3.46ValGly: 3.46 ± 0.024
1.626ValHis: 1.626 ± 0.015
2.97ValIle: 2.97 ± 0.018
3.324ValLys: 3.324 ± 0.023
6.433ValLeu: 6.433 ± 0.029
1.337ValMet: 1.337 ± 0.011
2.222ValAsn: 2.222 ± 0.017
3.646ValPro: 3.646 ± 0.023
2.738ValGln: 2.738 ± 0.018
2.995ValArg: 2.995 ± 0.02
4.847ValSer: 4.847 ± 0.023
3.782ValThr: 3.782 ± 0.027
4.059ValVal: 4.059 ± 0.024
0.72ValTrp: 0.72 ± 0.01
1.663ValTyr: 1.663 ± 0.014
0.001ValXaa: 0.001 ± 0.0
Trp
0.823TrpAla: 0.823 ± 0.009
0.25TrpCys: 0.25 ± 0.005
0.656TrpAsp: 0.656 ± 0.009
0.814TrpGlu: 0.814 ± 0.009
0.46TrpPhe: 0.46 ± 0.007
0.753TrpGly: 0.753 ± 0.011
0.312TrpHis: 0.312 ± 0.006
0.556TrpIle: 0.556 ± 0.008
0.818TrpLys: 0.818 ± 0.01
1.235TrpLeu: 1.235 ± 0.013
0.304TrpMet: 0.304 ± 0.006
0.534TrpAsn: 0.534 ± 0.007
0.524TrpPro: 0.524 ± 0.007
0.543TrpGln: 0.543 ± 0.007
0.725TrpArg: 0.725 ± 0.008
0.863TrpSer: 0.863 ± 0.01
0.669TrpThr: 0.669 ± 0.01
0.741TrpVal: 0.741 ± 0.009
0.193TrpTrp: 0.193 ± 0.005
0.347TrpTyr: 0.347 ± 0.007
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.42TyrAla: 1.42 ± 0.013
0.712TyrCys: 0.712 ± 0.009
1.295TyrAsp: 1.295 ± 0.013
1.709TyrGlu: 1.709 ± 0.015
1.319TyrPhe: 1.319 ± 0.013
1.723TyrGly: 1.723 ± 0.018
0.779TyrHis: 0.779 ± 0.009
1.402TyrIle: 1.402 ± 0.012
1.575TyrLys: 1.575 ± 0.023
2.787TyrLeu: 2.787 ± 0.019
0.609TyrMet: 0.609 ± 0.008
1.103TyrAsn: 1.103 ± 0.011
1.339TyrPro: 1.339 ± 0.013
1.254TyrGln: 1.254 ± 0.011
1.594TyrArg: 1.594 ± 0.015
2.275TyrSer: 2.275 ± 0.016
1.544TyrThr: 1.544 ± 0.015
1.648TyrVal: 1.648 ± 0.015
0.368TyrTrp: 0.368 ± 0.008
0.972TyrTyr: 0.972 ± 0.011
0.001TyrXaa: 0.001 ± 0.0
Xaa
0.003XaaAla: 0.003 ± 0.0
0.001XaaCys: 0.001 ± 0.0
0.002XaaAsp: 0.002 ± 0.0
0.002XaaGlu: 0.002 ± 0.0
0.001XaaPhe: 0.001 ± 0.0
0.002XaaGly: 0.002 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.002XaaLys: 0.002 ± 0.0
0.002XaaLeu: 0.002 ± 0.0
0.001XaaMet: 0.001 ± 0.0
0.001XaaAsn: 0.001 ± 0.0
0.002XaaPro: 0.002 ± 0.0
0.001XaaGln: 0.001 ± 0.0
0.001XaaArg: 0.001 ± 0.0
0.002XaaSer: 0.002 ± 0.0
0.001XaaThr: 0.001 ± 0.0
0.001XaaVal: 0.001 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.001XaaTyr: 0.001 ± 0.0
0.049XaaXaa: 0.049 ± 0.01
Statistics based on 19931 proteins (10768681 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski