Amino acid dipepetide frequency for Aeromicrobium camelliae

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	18.914AlaAla: 18.914 ± 0.223	0.875AlaCys: 0.875 ± 0.026	8.075AlaAsp: 8.075 ± 0.107	8.75AlaGlu: 8.75 ± 0.11	3.725AlaPhe: 3.725 ± 0.068	11.608AlaGly: 11.608 ± 0.134	2.536AlaHis: 2.536 ± 0.055	5.416AlaIle: 5.416 ± 0.086	2.525AlaLys: 2.525 ± 0.058	13.72AlaLeu: 13.72 ± 0.166	2.978AlaMet: 2.978 ± 0.057	2.047AlaAsn: 2.047 ± 0.051	5.908AlaPro: 5.908 ± 0.099	3.989AlaGln: 3.989 ± 0.075	9.323AlaArg: 9.323 ± 0.119	6.495AlaSer: 6.495 ± 0.096	7.25AlaThr: 7.25 ± 0.115	11.898AlaVal: 11.898 ± 0.16	1.903AlaTrp: 1.903 ± 0.041	2.418AlaTyr: 2.418 ± 0.048	0.0AlaXaa: 0.0 ± 0.0
Cys	0.799CysAla: 0.799 ± 0.034	0.058CysCys: 0.058 ± 0.008	0.423CysAsp: 0.423 ± 0.019	0.386CysGlu: 0.386 ± 0.021	0.21CysPhe: 0.21 ± 0.016	0.762CysGly: 0.762 ± 0.032	0.178CysHis: 0.178 ± 0.016	0.22CysIle: 0.22 ± 0.015	0.077CysLys: 0.077 ± 0.009	0.527CysLeu: 0.527 ± 0.023	0.091CysMet: 0.091 ± 0.009	0.109CysAsn: 0.109 ± 0.012	0.374CysPro: 0.374 ± 0.019	0.152CysGln: 0.152 ± 0.012	0.504CysArg: 0.504 ± 0.025	0.388CysSer: 0.388 ± 0.021	0.328CysThr: 0.328 ± 0.018	0.529CysVal: 0.529 ± 0.024	0.081CysTrp: 0.081 ± 0.008	0.107CysTyr: 0.107 ± 0.011	0.0CysXaa: 0.0 ± 0.0
Asp	8.538AspAla: 8.538 ± 0.1	0.274AspCys: 0.274 ± 0.017	4.83AspAsp: 4.83 ± 0.095	4.889AspGlu: 4.889 ± 0.084	1.698AspPhe: 1.698 ± 0.045	5.862AspGly: 5.862 ± 0.085	1.514AspHis: 1.514 ± 0.041	2.439AspIle: 2.439 ± 0.059	1.035AspLys: 1.035 ± 0.038	6.88AspLeu: 6.88 ± 0.095	0.874AspMet: 0.874 ± 0.03	0.868AspAsn: 0.868 ± 0.035	4.441AspPro: 4.441 ± 0.067	1.78AspGln: 1.78 ± 0.042	4.88AspArg: 4.88 ± 0.076	2.383AspSer: 2.383 ± 0.049	2.847AspThr: 2.847 ± 0.063	6.055AspVal: 6.055 ± 0.092	0.889AspTrp: 0.889 ± 0.03	1.179AspTyr: 1.179 ± 0.036	0.0AspXaa: 0.0 ± 0.0
Glu	7.476GluAla: 7.476 ± 0.113	0.3GluCys: 0.3 ± 0.021	3.353GluAsp: 3.353 ± 0.068	3.695GluGlu: 3.695 ± 0.07	1.794GluPhe: 1.794 ± 0.043	4.704GluGly: 4.704 ± 0.081	1.659GluHis: 1.659 ± 0.046	2.866GluIle: 2.866 ± 0.057	1.409GluLys: 1.409 ± 0.04	7.066GluLeu: 7.066 ± 0.1	1.01GluMet: 1.01 ± 0.031	1.349GluAsn: 1.349 ± 0.037	3.466GluPro: 3.466 ± 0.066	2.624GluGln: 2.624 ± 0.064	6.012GluArg: 6.012 ± 0.095	3.018GluSer: 3.018 ± 0.062	2.964GluThr: 2.964 ± 0.053	5.351GluVal: 5.351 ± 0.083	0.787GluTrp: 0.787 ± 0.027	1.156GluTyr: 1.156 ± 0.044	0.0GluXaa: 0.0 ± 0.0
Phe	4.062PheAla: 4.062 ± 0.068	0.239PheCys: 0.239 ± 0.015	2.269PheAsp: 2.269 ± 0.052	1.682PheGlu: 1.682 ± 0.046	0.931PhePhe: 0.931 ± 0.036	3.456PheGly: 3.456 ± 0.071	0.572PheHis: 0.572 ± 0.023	1.066PheIle: 1.066 ± 0.04	0.436PheLys: 0.436 ± 0.023	2.626PheLeu: 2.626 ± 0.057	0.483PheMet: 0.483 ± 0.02	0.56PheAsn: 0.56 ± 0.027	1.269PhePro: 1.269 ± 0.036	0.638PheGln: 0.638 ± 0.031	1.709PheArg: 1.709 ± 0.041	1.584PheSer: 1.584 ± 0.047	1.962PheThr: 1.962 ± 0.047	2.831PheVal: 2.831 ± 0.065	0.414PheTrp: 0.414 ± 0.022	0.635PheTyr: 0.635 ± 0.025	0.0PheXaa: 0.0 ± 0.0
Gly	10.316GlyAla: 10.316 ± 0.131	0.653GlyCys: 0.653 ± 0.026	5.354GlyAsp: 5.354 ± 0.084	5.265GlyGlu: 5.265 ± 0.086	3.028GlyPhe: 3.028 ± 0.058	7.592GlyGly: 7.592 ± 0.119	1.962GlyHis: 1.962 ± 0.046	4.151GlyIle: 4.151 ± 0.069	2.079GlyLys: 2.079 ± 0.054	8.968GlyLeu: 8.968 ± 0.102	1.817GlyMet: 1.817 ± 0.048	1.569GlyAsn: 1.569 ± 0.049	4.115GlyPro: 4.115 ± 0.066	2.742GlyGln: 2.742 ± 0.061	6.789GlyArg: 6.789 ± 0.086	4.932GlySer: 4.932 ± 0.079	5.475GlyThr: 5.475 ± 0.074	8.111GlyVal: 8.111 ± 0.107	1.597GlyTrp: 1.597 ± 0.046	2.137GlyTyr: 2.137 ± 0.046	0.0GlyXaa: 0.0 ± 0.0
His	2.516HisAla: 2.516 ± 0.056	0.152HisCys: 0.152 ± 0.013	1.486HisAsp: 1.486 ± 0.038	1.373HisGlu: 1.373 ± 0.042	0.561HisPhe: 0.561 ± 0.023	2.126HisGly: 2.126 ± 0.053	0.673HisHis: 0.673 ± 0.029	0.655HisIle: 0.655 ± 0.027	0.279HisLys: 0.279 ± 0.018	2.343HisLeu: 2.343 ± 0.051	0.288HisMet: 0.288 ± 0.019	0.325HisAsn: 0.325 ± 0.019	1.482HisPro: 1.482 ± 0.039	0.662HisGln: 0.662 ± 0.032	1.912HisArg: 1.912 ± 0.046	0.852HisSer: 0.852 ± 0.032	0.976HisThr: 0.976 ± 0.03	1.942HisVal: 1.942 ± 0.046	0.302HisTrp: 0.302 ± 0.02	0.421HisTyr: 0.421 ± 0.026	0.0HisXaa: 0.0 ± 0.0
Ile	6.633IleAla: 6.633 ± 0.09	0.294IleCys: 0.294 ± 0.019	3.34IleAsp: 3.34 ± 0.058	3.011IleGlu: 3.011 ± 0.066	0.99IlePhe: 0.99 ± 0.035	4.404IleGly: 4.404 ± 0.074	0.739IleHis: 0.739 ± 0.032	1.467IleIle: 1.467 ± 0.044	0.745IleLys: 0.745 ± 0.031	3.28IleLeu: 3.28 ± 0.068	0.604IleMet: 0.604 ± 0.027	0.869IleAsn: 0.869 ± 0.031	2.002IlePro: 2.002 ± 0.051	0.834IleGln: 0.834 ± 0.03	2.433IleArg: 2.433 ± 0.052	2.043IleSer: 2.043 ± 0.049	2.627IleThr: 2.627 ± 0.057	4.515IleVal: 4.515 ± 0.072	0.435IleTrp: 0.435 ± 0.021	0.664IleTyr: 0.664 ± 0.029	0.0IleXaa: 0.0 ± 0.0
Lys	2.398LysAla: 2.398 ± 0.066	0.076LysCys: 0.076 ± 0.008	1.019LysAsp: 1.019 ± 0.036	1.024LysGlu: 1.024 ± 0.036	0.438LysPhe: 0.438 ± 0.024	1.515LysGly: 1.515 ± 0.046	0.393LysHis: 0.393 ± 0.017	0.901LysIle: 0.901 ± 0.036	0.709LysLys: 0.709 ± 0.036	1.822LysLeu: 1.822 ± 0.041	0.358LysMet: 0.358 ± 0.02	0.515LysAsn: 0.515 ± 0.028	1.16LysPro: 1.16 ± 0.038	0.609LysGln: 0.609 ± 0.027	1.513LysArg: 1.513 ± 0.044	1.098LysSer: 1.098 ± 0.033	1.145LysThr: 1.145 ± 0.04	1.784LysVal: 1.784 ± 0.049	0.193LysTrp: 0.193 ± 0.014	0.39LysTyr: 0.39 ± 0.021	0.0LysXaa: 0.0 ± 0.0
Leu	14.754LeuAla: 14.754 ± 0.194	0.641LeuCys: 0.641 ± 0.027	7.248LeuAsp: 7.248 ± 0.095	5.546LeuGlu: 5.546 ± 0.09	2.52LeuPhe: 2.52 ± 0.058	9.301LeuGly: 9.301 ± 0.126	1.957LeuHis: 1.957 ± 0.047	3.866LeuIle: 3.866 ± 0.074	1.713LeuLys: 1.713 ± 0.045	10.119LeuLeu: 10.119 ± 0.149	1.781LeuMet: 1.781 ± 0.043	1.692LeuAsn: 1.692 ± 0.044	5.448LeuPro: 5.448 ± 0.081	2.478LeuGln: 2.478 ± 0.055	7.721LeuArg: 7.721 ± 0.109	5.62LeuSer: 5.62 ± 0.08	6.489LeuThr: 6.489 ± 0.081	10.137LeuVal: 10.137 ± 0.123	1.139LeuTrp: 1.139 ± 0.034	1.597LeuTyr: 1.597 ± 0.044	0.0LeuXaa: 0.0 ± 0.0
Met	2.345MetAla: 2.345 ± 0.052	0.123MetCys: 0.123 ± 0.011	0.864MetAsp: 0.864 ± 0.03	0.831MetGlu: 0.831 ± 0.03	0.552MetPhe: 0.552 ± 0.028	1.392MetGly: 1.392 ± 0.041	0.346MetHis: 0.346 ± 0.019	0.836MetIle: 0.836 ± 0.033	0.435MetLys: 0.435 ± 0.022	1.977MetLeu: 1.977 ± 0.048	0.377MetMet: 0.377 ± 0.022	0.446MetAsn: 0.446 ± 0.02	1.103MetPro: 1.103 ± 0.037	0.476MetGln: 0.476 ± 0.022	1.531MetArg: 1.531 ± 0.039	1.567MetSer: 1.567 ± 0.042	1.739MetThr: 1.739 ± 0.041	1.504MetVal: 1.504 ± 0.043	0.213MetTrp: 0.213 ± 0.015	0.298MetTyr: 0.298 ± 0.021	0.0MetXaa: 0.0 ± 0.0
Asn	2.369AsnAla: 2.369 ± 0.052	0.126AsnCys: 0.126 ± 0.012	1.074AsnAsp: 1.074 ± 0.033	0.987AsnGlu: 0.987 ± 0.032	0.542AsnPhe: 0.542 ± 0.027	1.73AsnGly: 1.73 ± 0.049	0.343AsnHis: 0.343 ± 0.02	0.732AsnIle: 0.732 ± 0.033	0.321AsnLys: 0.321 ± 0.018	1.742AsnLeu: 1.742 ± 0.046	0.297AsnMet: 0.297 ± 0.021	0.368AsnAsn: 0.368 ± 0.021	1.378AsnPro: 1.378 ± 0.038	0.544AsnGln: 0.544 ± 0.028	1.268AsnArg: 1.268 ± 0.039	0.831AsnSer: 0.831 ± 0.028	0.997AsnThr: 0.997 ± 0.037	1.679AsnVal: 1.679 ± 0.048	0.225AsnTrp: 0.225 ± 0.016	0.35AsnTyr: 0.35 ± 0.02	0.0AsnXaa: 0.0 ± 0.0
Pro	6.603ProAla: 6.603 ± 0.092	0.269ProCys: 0.269 ± 0.017	4.091ProAsp: 4.091 ± 0.067	4.096ProGlu: 4.096 ± 0.074	1.641ProPhe: 1.641 ± 0.042	4.991ProGly: 4.991 ± 0.086	1.216ProHis: 1.216 ± 0.04	2.025ProIle: 2.025 ± 0.049	1.024ProLys: 1.024 ± 0.033	4.821ProLeu: 4.821 ± 0.083	0.998ProMet: 0.998 ± 0.036	0.878ProAsn: 0.878 ± 0.035	2.502ProPro: 2.502 ± 0.067	1.7ProGln: 1.7 ± 0.046	3.619ProArg: 3.619 ± 0.068	3.033ProSer: 3.033 ± 0.054	3.223ProThr: 3.223 ± 0.064	4.813ProVal: 4.813 ± 0.082	0.907ProTrp: 0.907 ± 0.032	1.037ProTyr: 1.037 ± 0.034	0.0ProXaa: 0.0 ± 0.0
Gln	3.562GlnAla: 3.562 ± 0.068	0.148GlnCys: 0.148 ± 0.013	1.251GlnAsp: 1.251 ± 0.036	1.479GlnGlu: 1.479 ± 0.038	0.848GlnPhe: 0.848 ± 0.033	2.04GlnGly: 2.04 ± 0.052	0.695GlnHis: 0.695 ± 0.032	1.611GlnIle: 1.611 ± 0.038	0.586GlnLys: 0.586 ± 0.028	3.396GlnLeu: 3.396 ± 0.057	0.617GlnMet: 0.617 ± 0.026	0.575GlnAsn: 0.575 ± 0.026	1.538GlnPro: 1.538 ± 0.039	1.325GlnGln: 1.325 ± 0.043	2.848GlnArg: 2.848 ± 0.061	1.337GlnSer: 1.337 ± 0.042	1.478GlnThr: 1.478 ± 0.041	2.696GlnVal: 2.696 ± 0.059	0.517GlnTrp: 0.517 ± 0.025	0.576GlnTyr: 0.576 ± 0.028	0.0GlnXaa: 0.0 ± 0.0
Arg	8.551ArgAla: 8.551 ± 0.108	0.481ArgCys: 0.481 ± 0.023	4.776ArgAsp: 4.776 ± 0.079	5.218ArgGlu: 5.218 ± 0.074	2.482ArgPhe: 2.482 ± 0.05	5.677ArgGly: 5.677 ± 0.076	1.887ArgHis: 1.887 ± 0.049	3.423ArgIle: 3.423 ± 0.059	1.425ArgLys: 1.425 ± 0.047	8.002ArgLeu: 8.002 ± 0.124	1.751ArgMet: 1.751 ± 0.039	1.22ArgAsn: 1.22 ± 0.039	4.112ArgPro: 4.112 ± 0.07	2.318ArgGln: 2.318 ± 0.049	7.585ArgArg: 7.585 ± 0.124	4.195ArgSer: 4.195 ± 0.069	4.341ArgThr: 4.341 ± 0.079	6.233ArgVal: 6.233 ± 0.077	1.444ArgTrp: 1.444 ± 0.045	1.638ArgTyr: 1.638 ± 0.042	0.0ArgXaa: 0.0 ± 0.0
Ser	6.492SerAla: 6.492 ± 0.085	0.318SerCys: 0.318 ± 0.021	2.986SerAsp: 2.986 ± 0.06	2.814SerGlu: 2.814 ± 0.052	1.722SerPhe: 1.722 ± 0.047	5.35SerGly: 5.35 ± 0.089	1.007SerHis: 1.007 ± 0.032	2.21SerIle: 2.21 ± 0.052	0.962SerLys: 0.962 ± 0.033	5.134SerLeu: 5.134 ± 0.078	1.283SerMet: 1.283 ± 0.04	0.958SerAsn: 0.958 ± 0.036	2.85SerPro: 2.85 ± 0.057	1.449SerGln: 1.449 ± 0.041	3.807SerArg: 3.807 ± 0.067	3.211SerSer: 3.211 ± 0.07	3.414SerThr: 3.414 ± 0.057	4.558SerVal: 4.558 ± 0.071	0.869SerTrp: 0.869 ± 0.028	1.167SerTyr: 1.167 ± 0.037	0.0SerXaa: 0.0 ± 0.0
Thr	7.437ThrAla: 7.437 ± 0.096	0.373ThrCys: 0.373 ± 0.021	3.342ThrAsp: 3.342 ± 0.063	3.092ThrGlu: 3.092 ± 0.055	1.872ThrPhe: 1.872 ± 0.042	5.468ThrGly: 5.468 ± 0.085	1.138ThrHis: 1.138 ± 0.036	2.831ThrIle: 2.831 ± 0.062	1.069ThrLys: 1.069 ± 0.038	5.885ThrLeu: 5.885 ± 0.084	1.117ThrMet: 1.117 ± 0.038	1.084ThrAsn: 1.084 ± 0.037	3.587ThrPro: 3.587 ± 0.066	1.519ThrGln: 1.519 ± 0.047	3.809ThrArg: 3.809 ± 0.067	3.372ThrSer: 3.372 ± 0.07	3.836ThrThr: 3.836 ± 0.065	5.871ThrVal: 5.871 ± 0.08	0.889ThrTrp: 0.889 ± 0.03	1.32ThrTyr: 1.32 ± 0.04	0.0ThrXaa: 0.0 ± 0.0
Val	12.48ValAla: 12.48 ± 0.141	0.639ValCys: 0.639 ± 0.024	6.178ValAsp: 6.178 ± 0.103	6.023ValGlu: 6.023 ± 0.086	2.701ValPhe: 2.701 ± 0.055	7.696ValGly: 7.696 ± 0.11	1.85ValHis: 1.85 ± 0.046	3.964ValIle: 3.964 ± 0.064	1.663ValLys: 1.663 ± 0.051	9.72ValLeu: 9.72 ± 0.127	1.702ValMet: 1.702 ± 0.05	1.768ValAsn: 1.768 ± 0.044	4.989ValPro: 4.989 ± 0.073	2.212ValGln: 2.212 ± 0.056	6.503ValArg: 6.503 ± 0.085	4.776ValSer: 4.776 ± 0.079	5.949ValThr: 5.949 ± 0.105	9.893ValVal: 9.893 ± 0.124	1.134ValTrp: 1.134 ± 0.039	1.51ValTyr: 1.51 ± 0.04	0.0ValXaa: 0.0 ± 0.0
Trp	1.577TrpAla: 1.577 ± 0.045	0.132TrpCys: 0.132 ± 0.012	0.806TrpAsp: 0.806 ± 0.031	0.687TrpGlu: 0.687 ± 0.025	0.517TrpPhe: 0.517 ± 0.027	1.036TrpGly: 1.036 ± 0.035	0.334TrpHis: 0.334 ± 0.022	0.641TrpIle: 0.641 ± 0.028	0.3TrpLys: 0.3 ± 0.018	1.674TrpLeu: 1.674 ± 0.047	0.302TrpMet: 0.302 ± 0.017	0.36TrpAsn: 0.36 ± 0.021	0.764TrpPro: 0.764 ± 0.03	0.519TrpGln: 0.519 ± 0.023	1.29TrpArg: 1.29 ± 0.042	0.957TrpSer: 0.957 ± 0.035	0.892TrpThr: 0.892 ± 0.031	1.127TrpVal: 1.127 ± 0.035	0.377TrpTrp: 0.377 ± 0.022	0.303TrpTyr: 0.303 ± 0.019	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.534TyrAla: 2.534 ± 0.053	0.132TyrCys: 0.132 ± 0.012	1.387TyrAsp: 1.387 ± 0.041	1.213TyrGlu: 1.213 ± 0.037	0.653TyrPhe: 0.653 ± 0.028	1.941TyrGly: 1.941 ± 0.049	0.325TyrHis: 0.325 ± 0.022	0.615TyrIle: 0.615 ± 0.029	0.269TyrLys: 0.269 ± 0.019	2.062TyrLeu: 2.062 ± 0.053	0.226TyrMet: 0.226 ± 0.016	0.342TyrAsn: 0.342 ± 0.02	0.999TyrPro: 0.999 ± 0.033	0.552TyrGln: 0.552 ± 0.026	1.702TyrArg: 1.702 ± 0.047	0.869TyrSer: 0.869 ± 0.033	0.981TyrThr: 0.981 ± 0.036	1.821TyrVal: 1.821 ± 0.041	0.279TyrTrp: 0.279 ± 0.017	0.428TyrTyr: 0.428 ± 0.024	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 2929 proteins (930471 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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