Amino acid dipepetide frequency for Leptotrichia goodfellowii F0264

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	3.828AlaAla: 3.828 ± 0.095	0.398AlaCys: 0.398 ± 0.025	2.778AlaAsp: 2.778 ± 0.054	4.045AlaGlu: 4.045 ± 0.08	2.335AlaPhe: 2.335 ± 0.063	4.429AlaGly: 4.429 ± 0.114	0.747AlaHis: 0.747 ± 0.035	4.362AlaIle: 4.362 ± 0.089	4.818AlaLys: 4.818 ± 0.102	4.935AlaLeu: 4.935 ± 0.104	1.358AlaMet: 1.358 ± 0.046	2.355AlaAsn: 2.355 ± 0.065	1.276AlaPro: 1.276 ± 0.051	1.41AlaGln: 1.41 ± 0.048	1.697AlaArg: 1.697 ± 0.049	2.81AlaSer: 2.81 ± 0.075	2.728AlaThr: 2.728 ± 0.074	4.185AlaVal: 4.185 ± 0.093	0.346AlaTrp: 0.346 ± 0.025	2.015AlaTyr: 2.015 ± 0.06	0.0AlaXaa: 0.0 ± 0.0
Cys	0.322CysAla: 0.322 ± 0.023	0.083CysCys: 0.083 ± 0.01	0.309CysAsp: 0.309 ± 0.019	0.47CysGlu: 0.47 ± 0.032	0.324CysPhe: 0.324 ± 0.024	0.634CysGly: 0.634 ± 0.03	0.106CysHis: 0.106 ± 0.012	0.595CysIle: 0.595 ± 0.026	0.496CysLys: 0.496 ± 0.032	0.551CysLeu: 0.551 ± 0.032	0.162CysMet: 0.162 ± 0.016	0.356CysAsn: 0.356 ± 0.022	0.248CysPro: 0.248 ± 0.019	0.131CysGln: 0.131 ± 0.014	0.214CysArg: 0.214 ± 0.017	0.446CysSer: 0.446 ± 0.027	0.331CysThr: 0.331 ± 0.021	0.379CysVal: 0.379 ± 0.025	0.058CysTrp: 0.058 ± 0.01	0.244CysTyr: 0.244 ± 0.018	0.0CysXaa: 0.0 ± 0.0
Asp	2.26AspAla: 2.26 ± 0.066	0.343AspCys: 0.343 ± 0.023	2.428AspAsp: 2.428 ± 0.058	4.494AspGlu: 4.494 ± 0.098	3.078AspPhe: 3.078 ± 0.066	3.243AspGly: 3.243 ± 0.065	0.499AspHis: 0.499 ± 0.029	5.458AspIle: 5.458 ± 0.093	5.733AspLys: 5.733 ± 0.094	4.656AspLeu: 4.656 ± 0.094	1.312AspMet: 1.312 ± 0.042	2.903AspAsn: 2.903 ± 0.074	1.296AspPro: 1.296 ± 0.051	0.789AspGln: 0.789 ± 0.029	1.894AspArg: 1.894 ± 0.057	2.785AspSer: 2.785 ± 0.063	2.549AspThr: 2.549 ± 0.058	3.108AspVal: 3.108 ± 0.076	0.487AspTrp: 0.487 ± 0.026	2.855AspTyr: 2.855 ± 0.065	0.0AspXaa: 0.0 ± 0.0
Glu	4.038GluAla: 4.038 ± 0.092	0.36GluCys: 0.36 ± 0.022	3.831GluAsp: 3.831 ± 0.077	7.63GluGlu: 7.63 ± 0.138	3.42GluPhe: 3.42 ± 0.067	3.993GluGly: 3.993 ± 0.085	0.958GluHis: 0.958 ± 0.038	8.903GluIle: 8.903 ± 0.144	11.869GluLys: 11.869 ± 0.188	6.799GluLeu: 6.799 ± 0.112	2.217GluMet: 2.217 ± 0.058	7.159GluAsn: 7.159 ± 0.132	1.311GluPro: 1.311 ± 0.042	1.74GluGln: 1.74 ± 0.056	2.982GluArg: 2.982 ± 0.071	3.409GluSer: 3.409 ± 0.077	3.646GluThr: 3.646 ± 0.082	4.693GluVal: 4.693 ± 0.1	0.566GluTrp: 0.566 ± 0.032	3.646GluTyr: 3.646 ± 0.073	0.0GluXaa: 0.0 ± 0.0
Phe	2.32PheAla: 2.32 ± 0.072	0.35PheCys: 0.35 ± 0.022	2.756PheAsp: 2.756 ± 0.061	3.703PheGlu: 3.703 ± 0.076	2.577PhePhe: 2.577 ± 0.082	3.431PheGly: 3.431 ± 0.076	0.569PheHis: 0.569 ± 0.03	4.359PheIle: 4.359 ± 0.094	3.986PheLys: 3.986 ± 0.078	4.546PheLeu: 4.546 ± 0.103	1.207PheMet: 1.207 ± 0.044	2.586PheAsn: 2.586 ± 0.066	1.39PhePro: 1.39 ± 0.04	1.181PheGln: 1.181 ± 0.044	1.455PheArg: 1.455 ± 0.041	3.605PheSer: 3.605 ± 0.087	2.362PheThr: 2.362 ± 0.063	2.858PheVal: 2.858 ± 0.072	0.386PheTrp: 0.386 ± 0.026	2.12PheTyr: 2.12 ± 0.073	0.0PheXaa: 0.0 ± 0.0
Gly	3.885GlyAla: 3.885 ± 0.099	0.44GlyCys: 0.44 ± 0.026	2.991GlyAsp: 2.991 ± 0.074	4.653GlyGlu: 4.653 ± 0.1	3.051GlyPhe: 3.051 ± 0.075	4.499GlyGly: 4.499 ± 0.115	1.024GlyHis: 1.024 ± 0.044	7.273GlyIle: 7.273 ± 0.126	6.978GlyLys: 6.978 ± 0.117	5.406GlyLeu: 5.406 ± 0.113	1.867GlyMet: 1.867 ± 0.054	4.035GlyAsn: 4.035 ± 0.098	1.205GlyPro: 1.205 ± 0.051	1.549GlyGln: 1.549 ± 0.048	2.26GlyArg: 2.26 ± 0.052	3.571GlySer: 3.571 ± 0.089	3.885GlyThr: 3.885 ± 0.114	4.639GlyVal: 4.639 ± 0.091	0.497GlyTrp: 0.497 ± 0.025	3.02GlyTyr: 3.02 ± 0.065	0.0GlyXaa: 0.0 ± 0.0
His	0.646HisAla: 0.646 ± 0.033	0.111HisCys: 0.111 ± 0.011	0.627HisAsp: 0.627 ± 0.031	0.853HisGlu: 0.853 ± 0.039	0.601HisPhe: 0.601 ± 0.032	0.92HisGly: 0.92 ± 0.042	0.258HisHis: 0.258 ± 0.024	1.114HisIle: 1.114 ± 0.039	0.955HisLys: 0.955 ± 0.039	1.046HisLeu: 1.046 ± 0.043	0.287HisMet: 0.287 ± 0.02	0.732HisAsn: 0.732 ± 0.035	0.586HisPro: 0.586 ± 0.031	0.295HisGln: 0.295 ± 0.022	0.49HisArg: 0.49 ± 0.024	0.857HisSer: 0.857 ± 0.036	0.739HisThr: 0.739 ± 0.035	0.707HisVal: 0.707 ± 0.034	0.095HisTrp: 0.095 ± 0.011	0.548HisTyr: 0.548 ± 0.026	0.0HisXaa: 0.0 ± 0.0
Ile	5.108IleAla: 5.108 ± 0.099	0.688IleCys: 0.688 ± 0.034	4.955IleAsp: 4.955 ± 0.101	7.348IleGlu: 7.348 ± 0.122	4.855IlePhe: 4.855 ± 0.106	6.01IleGly: 6.01 ± 0.1	1.089IleHis: 1.089 ± 0.04	9.09IleIle: 9.09 ± 0.161	9.132IleLys: 9.132 ± 0.157	9.06IleLeu: 9.06 ± 0.15	2.25IleMet: 2.25 ± 0.068	5.925IleAsn: 5.925 ± 0.102	3.084IlePro: 3.084 ± 0.071	2.011IleGln: 2.011 ± 0.052	3.004IleArg: 3.004 ± 0.067	6.449IleSer: 6.449 ± 0.107	4.669IleThr: 4.669 ± 0.081	5.787IleVal: 5.787 ± 0.096	0.567IleTrp: 0.567 ± 0.029	3.729IleTyr: 3.729 ± 0.08	0.0IleXaa: 0.0 ± 0.0
Lys	4.772LysAla: 4.772 ± 0.103	0.465LysCys: 0.465 ± 0.031	5.899LysAsp: 5.899 ± 0.12	10.615LysGlu: 10.615 ± 0.16	4.104LysPhe: 4.104 ± 0.082	5.894LysGly: 5.894 ± 0.086	1.027LysHis: 1.027 ± 0.039	10.714LysIle: 10.714 ± 0.158	11.56LysLys: 11.56 ± 0.174	7.974LysLeu: 7.974 ± 0.108	2.944LysMet: 2.944 ± 0.072	8.185LysAsn: 8.185 ± 0.14	2.015LysPro: 2.015 ± 0.05	2.097LysGln: 2.097 ± 0.055	3.44LysArg: 3.44 ± 0.073	5.327LysSer: 5.327 ± 0.092	4.767LysThr: 4.767 ± 0.09	6.024LysVal: 6.024 ± 0.1	0.785LysTrp: 0.785 ± 0.038	5.177LysTyr: 5.177 ± 0.098	0.0LysXaa: 0.0 ± 0.0
Leu	4.688LeuAla: 4.688 ± 0.098	0.569LeuCys: 0.569 ± 0.029	4.487LeuAsp: 4.487 ± 0.086	6.976LeuGlu: 6.976 ± 0.129	4.19LeuPhe: 4.19 ± 0.098	6.014LeuGly: 6.014 ± 0.107	1.06LeuHis: 1.06 ± 0.043	7.496LeuIle: 7.496 ± 0.131	9.69LeuLys: 9.69 ± 0.118	7.703LeuLeu: 7.703 ± 0.14	2.247LeuMet: 2.247 ± 0.062	5.418LeuAsn: 5.418 ± 0.106	2.747LeuPro: 2.747 ± 0.074	2.015LeuGln: 2.015 ± 0.058	2.95LeuArg: 2.95 ± 0.065	6.153LeuSer: 6.153 ± 0.109	4.471LeuThr: 4.471 ± 0.09	4.645LeuVal: 4.645 ± 0.102	0.556LeuTrp: 0.556 ± 0.028	3.057LeuTyr: 3.057 ± 0.075	0.001LeuXaa: 0.001 ± 0.001
Met	1.528MetAla: 1.528 ± 0.053	0.156MetCys: 0.156 ± 0.016	1.156MetAsp: 1.156 ± 0.045	1.964MetGlu: 1.964 ± 0.047	1.069MetPhe: 1.069 ± 0.039	1.604MetGly: 1.604 ± 0.05	0.279MetHis: 0.279 ± 0.019	2.243MetIle: 2.243 ± 0.07	3.274MetLys: 3.274 ± 0.063	2.284MetLeu: 2.284 ± 0.063	0.601MetMet: 0.601 ± 0.03	1.482MetAsn: 1.482 ± 0.048	0.763MetPro: 0.763 ± 0.04	0.521MetGln: 0.521 ± 0.027	0.927MetArg: 0.927 ± 0.034	1.625MetSer: 1.625 ± 0.046	1.38MetThr: 1.38 ± 0.05	1.193MetVal: 1.193 ± 0.041	0.171MetTrp: 0.171 ± 0.015	0.903MetTyr: 0.903 ± 0.039	0.0MetXaa: 0.0 ± 0.0
Asn	2.803AsnAla: 2.803 ± 0.073	0.373AsnCys: 0.373 ± 0.026	3.122AsnAsp: 3.122 ± 0.067	4.958AsnGlu: 4.958 ± 0.105	3.052AsnPhe: 3.052 ± 0.069	4.216AsnGly: 4.216 ± 0.117	0.719AsnHis: 0.719 ± 0.033	6.949AsnIle: 6.949 ± 0.125	6.209AsnLys: 6.209 ± 0.115	5.423AsnLeu: 5.423 ± 0.097	1.559AsnMet: 1.559 ± 0.049	4.058AsnAsn: 4.058 ± 0.107	2.288AsnPro: 2.288 ± 0.055	1.38AsnGln: 1.38 ± 0.041	2.139AsnArg: 2.139 ± 0.068	3.66AsnSer: 3.66 ± 0.096	3.032AsnThr: 3.032 ± 0.077	3.964AsnVal: 3.964 ± 0.09	0.491AsnTrp: 0.491 ± 0.029	2.79AsnTyr: 2.79 ± 0.068	0.0AsnXaa: 0.0 ± 0.0
Pro	1.423ProAla: 1.423 ± 0.047	0.165ProCys: 0.165 ± 0.016	1.674ProAsp: 1.674 ± 0.053	2.876ProGlu: 2.876 ± 0.068	1.39ProPhe: 1.39 ± 0.054	1.627ProGly: 1.627 ± 0.061	0.432ProHis: 0.432 ± 0.029	1.957ProIle: 1.957 ± 0.059	2.227ProLys: 2.227 ± 0.056	2.408ProLeu: 2.408 ± 0.064	0.604ProMet: 0.604 ± 0.028	1.476ProAsn: 1.476 ± 0.048	0.487ProPro: 0.487 ± 0.026	0.76ProGln: 0.76 ± 0.032	0.693ProArg: 0.693 ± 0.032	1.496ProSer: 1.496 ± 0.053	1.394ProThr: 1.394 ± 0.056	2.3ProVal: 2.3 ± 0.055	0.217ProTrp: 0.217 ± 0.018	1.253ProTyr: 1.253 ± 0.037	0.0ProXaa: 0.0 ± 0.0
Gln	1.31GlnAla: 1.31 ± 0.048	0.125GlnCys: 0.125 ± 0.015	1.015GlnAsp: 1.015 ± 0.041	1.8GlnGlu: 1.8 ± 0.055	0.938GlnPhe: 0.938 ± 0.034	1.46GlnGly: 1.46 ± 0.041	0.249GlnHis: 0.249 ± 0.017	2.128GlnIle: 2.128 ± 0.053	2.562GlnLys: 2.562 ± 0.066	1.823GlnLeu: 1.823 ± 0.053	0.652GlnMet: 0.652 ± 0.029	1.595GlnAsn: 1.595 ± 0.047	0.5GlnPro: 0.5 ± 0.027	0.61GlnGln: 0.61 ± 0.033	0.881GlnArg: 0.881 ± 0.036	1.17GlnSer: 1.17 ± 0.043	1.181GlnThr: 1.181 ± 0.041	1.251GlnVal: 1.251 ± 0.048	0.211GlnTrp: 0.211 ± 0.018	0.97GlnTyr: 0.97 ± 0.038	0.0GlnXaa: 0.0 ± 0.0
Arg	1.817ArgAla: 1.817 ± 0.057	0.19ArgCys: 0.19 ± 0.015	1.76ArgAsp: 1.76 ± 0.048	3.183ArgGlu: 3.183 ± 0.079	1.46ArgPhe: 1.46 ± 0.042	2.037ArgGly: 2.037 ± 0.069	0.465ArgHis: 0.465 ± 0.029	3.108ArgIle: 3.108 ± 0.067	3.955ArgLys: 3.955 ± 0.075	2.794ArgLeu: 2.794 ± 0.067	0.892ArgMet: 0.892 ± 0.037	2.17ArgAsn: 2.17 ± 0.062	0.808ArgPro: 0.808 ± 0.037	0.913ArgGln: 0.913 ± 0.032	1.272ArgArg: 1.272 ± 0.041	1.412ArgSer: 1.412 ± 0.043	1.565ArgThr: 1.565 ± 0.054	2.069ArgVal: 2.069 ± 0.06	0.2ArgTrp: 0.2 ± 0.017	1.485ArgTyr: 1.485 ± 0.055	0.0ArgXaa: 0.0 ± 0.0
Ser	2.952SerAla: 2.952 ± 0.074	0.471SerCys: 0.471 ± 0.028	3.297SerAsp: 3.297 ± 0.079	5.053SerGlu: 5.053 ± 0.083	3.089SerPhe: 3.089 ± 0.077	4.637SerGly: 4.637 ± 0.11	0.817SerHis: 0.817 ± 0.031	4.853SerIle: 4.853 ± 0.078	5.528SerLys: 5.528 ± 0.084	5.019SerLeu: 5.019 ± 0.087	1.295SerMet: 1.295 ± 0.047	3.131SerAsn: 3.131 ± 0.073	1.608SerPro: 1.608 ± 0.048	1.512SerGln: 1.512 ± 0.049	1.951SerArg: 1.951 ± 0.054	3.401SerSer: 3.401 ± 0.095	2.852SerThr: 2.852 ± 0.076	4.01SerVal: 4.01 ± 0.083	0.429SerTrp: 0.429 ± 0.028	2.485SerTyr: 2.485 ± 0.058	0.0SerXaa: 0.0 ± 0.0
Thr	3.226ThrAla: 3.226 ± 0.079	0.303ThrCys: 0.303 ± 0.023	2.902ThrAsp: 2.902 ± 0.065	3.924ThrGlu: 3.924 ± 0.069	2.294ThrPhe: 2.294 ± 0.061	4.642ThrGly: 4.642 ± 0.096	0.734ThrHis: 0.734 ± 0.037	3.942ThrIle: 3.942 ± 0.086	4.025ThrLys: 4.025 ± 0.084	4.462ThrLeu: 4.462 ± 0.082	1.059ThrMet: 1.059 ± 0.046	2.387ThrAsn: 2.387 ± 0.07	1.747ThrPro: 1.747 ± 0.045	1.094ThrGln: 1.094 ± 0.039	1.527ThrArg: 1.527 ± 0.055	2.698ThrSer: 2.698 ± 0.076	2.578ThrThr: 2.578 ± 0.076	4.306ThrVal: 4.306 ± 0.084	0.324ThrTrp: 0.324 ± 0.021	1.765ThrTyr: 1.765 ± 0.051	0.0ThrXaa: 0.0 ± 0.0
Val	3.526ValAla: 3.526 ± 0.081	0.483ValCys: 0.483 ± 0.029	3.328ValAsp: 3.328 ± 0.073	4.675ValGlu: 4.675 ± 0.091	3.214ValPhe: 3.214 ± 0.083	4.012ValGly: 4.012 ± 0.095	0.755ValHis: 0.755 ± 0.036	5.893ValIle: 5.893 ± 0.124	6.015ValLys: 6.015 ± 0.097	5.899ValLeu: 5.899 ± 0.104	1.439ValMet: 1.439 ± 0.055	3.78ValAsn: 3.78 ± 0.092	1.98ValPro: 1.98 ± 0.054	1.314ValGln: 1.314 ± 0.046	1.923ValArg: 1.923 ± 0.049	4.236ValSer: 4.236 ± 0.078	3.386ValThr: 3.386 ± 0.076	3.891ValVal: 3.891 ± 0.091	0.451ValTrp: 0.451 ± 0.026	2.616ValTyr: 2.616 ± 0.065	0.0ValXaa: 0.0 ± 0.0
Trp	0.417TrpAla: 0.417 ± 0.025	0.048TrpCys: 0.048 ± 0.007	0.449TrpAsp: 0.449 ± 0.029	0.618TrpGlu: 0.618 ± 0.028	0.353TrpPhe: 0.353 ± 0.023	0.522TrpGly: 0.522 ± 0.032	0.112TrpHis: 0.112 ± 0.012	0.607TrpIle: 0.607 ± 0.032	0.694TrpLys: 0.694 ± 0.032	0.596TrpLeu: 0.596 ± 0.03	0.174TrpMet: 0.174 ± 0.016	0.499TrpAsn: 0.499 ± 0.026	0.153TrpPro: 0.153 ± 0.014	0.216TrpGln: 0.216 ± 0.017	0.239TrpArg: 0.239 ± 0.021	0.379TrpSer: 0.379 ± 0.022	0.389TrpThr: 0.389 ± 0.028	0.375TrpVal: 0.375 ± 0.027	0.099TrpTrp: 0.099 ± 0.012	0.337TrpTyr: 0.337 ± 0.025	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.986TyrAla: 1.986 ± 0.056	0.338TyrCys: 0.338 ± 0.021	2.408TyrAsp: 2.408 ± 0.066	3.328TyrGlu: 3.328 ± 0.082	2.357TyrPhe: 2.357 ± 0.067	2.902TyrGly: 2.902 ± 0.067	0.57TyrHis: 0.57 ± 0.032	3.771TyrIle: 3.771 ± 0.077	4.079TyrLys: 4.079 ± 0.089	3.749TyrLeu: 3.749 ± 0.094	0.993TyrMet: 0.993 ± 0.039	2.955TyrAsn: 2.955 ± 0.082	1.364TyrPro: 1.364 ± 0.044	0.894TyrGln: 0.894 ± 0.036	1.611TyrArg: 1.611 ± 0.049	2.902TyrSer: 2.902 ± 0.074	2.031TyrThr: 2.031 ± 0.059	2.434TyrVal: 2.434 ± 0.06	0.341TyrTrp: 0.341 ± 0.022	2.084TyrTyr: 2.084 ± 0.064	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.001XaaArg: 0.001 ± 0.001	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 2374 proteins (685734 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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