Amino acid dipepetide frequency for Moellerella wisconsensis ATCC 35017

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
7.921AlaAla: 7.921 ± 0.144
0.918AlaCys: 0.918 ± 0.034
4.508AlaAsp: 4.508 ± 0.068
5.766AlaGlu: 5.766 ± 0.119
3.038AlaPhe: 3.038 ± 0.061
6.215AlaGly: 6.215 ± 0.104
1.524AlaHis: 1.524 ± 0.043
6.494AlaIle: 6.494 ± 0.092
4.555AlaLys: 4.555 ± 0.079
9.413AlaLeu: 9.413 ± 0.125
2.423AlaMet: 2.423 ± 0.052
3.39AlaAsn: 3.39 ± 0.064
2.959AlaPro: 2.959 ± 0.067
4.074AlaGln: 4.074 ± 0.076
3.781AlaArg: 3.781 ± 0.074
4.679AlaSer: 4.679 ± 0.076
4.229AlaThr: 4.229 ± 0.065
5.56AlaVal: 5.56 ± 0.094
0.978AlaTrp: 0.978 ± 0.035
2.31AlaTyr: 2.31 ± 0.061
0.0AlaXaa: 0.0 ± 0.0
Cys
0.83CysAla: 0.83 ± 0.034
0.178CysCys: 0.178 ± 0.015
0.578CysAsp: 0.578 ± 0.026
0.545CysGlu: 0.545 ± 0.026
0.43CysPhe: 0.43 ± 0.02
0.966CysGly: 0.966 ± 0.034
0.34CysHis: 0.34 ± 0.02
0.631CysIle: 0.631 ± 0.029
0.347CysLys: 0.347 ± 0.02
1.042CysLeu: 1.042 ± 0.04
0.212CysMet: 0.212 ± 0.016
0.327CysAsn: 0.327 ± 0.017
0.469CysPro: 0.469 ± 0.022
0.525CysGln: 0.525 ± 0.028
0.525CysArg: 0.525 ± 0.024
0.704CysSer: 0.704 ± 0.033
0.461CysThr: 0.461 ± 0.024
0.676CysVal: 0.676 ± 0.028
0.162CysTrp: 0.162 ± 0.015
0.393CysTyr: 0.393 ± 0.019
0.0CysXaa: 0.0 ± 0.0
Asp
4.096AspAla: 4.096 ± 0.063
0.512AspCys: 0.512 ± 0.025
2.853AspAsp: 2.853 ± 0.068
3.466AspGlu: 3.466 ± 0.066
2.297AspPhe: 2.297 ± 0.053
3.351AspGly: 3.351 ± 0.073
1.061AspHis: 1.061 ± 0.036
4.364AspIle: 4.364 ± 0.072
3.279AspLys: 3.279 ± 0.065
4.756AspLeu: 4.756 ± 0.061
1.374AspMet: 1.374 ± 0.042
2.989AspAsn: 2.989 ± 0.081
2.192AspPro: 2.192 ± 0.052
1.935AspGln: 1.935 ± 0.052
2.171AspArg: 2.171 ± 0.055
3.138AspSer: 3.138 ± 0.06
2.421AspThr: 2.421 ± 0.053
3.34AspVal: 3.34 ± 0.068
0.757AspTrp: 0.757 ± 0.029
2.121AspTyr: 2.121 ± 0.05
0.0AspXaa: 0.0 ± 0.0
Glu
4.455GluAla: 4.455 ± 0.098
0.51GluCys: 0.51 ± 0.025
2.485GluAsp: 2.485 ± 0.059
3.059GluGlu: 3.059 ± 0.077
2.056GluPhe: 2.056 ± 0.05
3.289GluGly: 3.289 ± 0.062
1.414GluHis: 1.414 ± 0.046
4.2GluIle: 4.2 ± 0.073
3.815GluLys: 3.815 ± 0.068
6.348GluLeu: 6.348 ± 0.109
1.682GluMet: 1.682 ± 0.041
2.909GluAsn: 2.909 ± 0.06
1.927GluPro: 1.927 ± 0.051
3.879GluGln: 3.879 ± 0.095
3.12GluArg: 3.12 ± 0.07
3.071GluSer: 3.071 ± 0.061
2.815GluThr: 2.815 ± 0.066
3.522GluVal: 3.522 ± 0.064
0.768GluTrp: 0.768 ± 0.029
1.724GluTyr: 1.724 ± 0.041
0.0GluXaa: 0.0 ± 0.0
Phe
3.258PheAla: 3.258 ± 0.066
0.505PheCys: 0.505 ± 0.027
2.456PheAsp: 2.456 ± 0.058
1.954PheGlu: 1.954 ± 0.048
1.756PhePhe: 1.756 ± 0.059
3.049PheGly: 3.049 ± 0.058
0.781PheHis: 0.781 ± 0.03
3.342PheIle: 3.342 ± 0.069
1.73PheLys: 1.73 ± 0.046
3.388PheLeu: 3.388 ± 0.075
1.065PheMet: 1.065 ± 0.032
2.193PheAsn: 2.193 ± 0.052
1.414PhePro: 1.414 ± 0.045
1.153PheGln: 1.153 ± 0.036
1.6PheArg: 1.6 ± 0.039
3.56PheSer: 3.56 ± 0.071
2.365PheThr: 2.365 ± 0.06
2.31PheVal: 2.31 ± 0.06
0.552PheTrp: 0.552 ± 0.025
1.382PheTyr: 1.382 ± 0.04
0.0PheXaa: 0.0 ± 0.0
Gly
5.31GlyAla: 5.31 ± 0.083
0.935GlyCys: 0.935 ± 0.036
3.479GlyAsp: 3.479 ± 0.073
3.982GlyGlu: 3.982 ± 0.078
3.162GlyPhe: 3.162 ± 0.062
4.702GlyGly: 4.702 ± 0.096
1.61GlyHis: 1.61 ± 0.044
5.487GlyIle: 5.487 ± 0.09
3.922GlyLys: 3.922 ± 0.075
6.983GlyLeu: 6.983 ± 0.093
2.033GlyMet: 2.033 ± 0.047
2.722GlyAsn: 2.722 ± 0.077
1.751GlyPro: 1.751 ± 0.047
2.933GlyGln: 2.933 ± 0.06
3.25GlyArg: 3.25 ± 0.066
4.01GlySer: 4.01 ± 0.076
3.412GlyThr: 3.412 ± 0.066
4.839GlyVal: 4.839 ± 0.089
1.02GlyTrp: 1.02 ± 0.033
2.581GlyTyr: 2.581 ± 0.059
0.0GlyXaa: 0.0 ± 0.0
His
1.665HisAla: 1.665 ± 0.045
0.309HisCys: 0.309 ± 0.022
1.079HisAsp: 1.079 ± 0.039
1.04HisGlu: 1.04 ± 0.035
1.07HisPhe: 1.07 ± 0.037
1.567HisGly: 1.567 ± 0.047
0.74HisHis: 0.74 ± 0.035
1.517HisIle: 1.517 ± 0.043
0.964HisLys: 0.964 ± 0.033
2.101HisLeu: 2.101 ± 0.06
0.485HisMet: 0.485 ± 0.025
0.98HisAsn: 0.98 ± 0.032
1.267HisPro: 1.267 ± 0.036
1.457HisGln: 1.457 ± 0.044
1.125HisArg: 1.125 ± 0.036
1.315HisSer: 1.315 ± 0.04
1.031HisThr: 1.031 ± 0.036
1.082HisVal: 1.082 ± 0.037
0.402HisTrp: 0.402 ± 0.022
0.928HisTyr: 0.928 ± 0.032
0.0HisXaa: 0.0 ± 0.0
Ile
6.955IleAla: 6.955 ± 0.09
0.784IleCys: 0.784 ± 0.032
4.659IleAsp: 4.659 ± 0.07
4.633IleGlu: 4.633 ± 0.077
2.817IlePhe: 2.817 ± 0.065
5.31IleGly: 5.31 ± 0.092
1.378IleHis: 1.378 ± 0.038
5.674IleIle: 5.674 ± 0.098
3.745IleLys: 3.745 ± 0.058
6.703IleLeu: 6.703 ± 0.117
1.633IleMet: 1.633 ± 0.052
4.147IleAsn: 4.147 ± 0.092
3.15IlePro: 3.15 ± 0.057
2.543IleGln: 2.543 ± 0.057
3.198IleArg: 3.198 ± 0.065
5.154IleSer: 5.154 ± 0.089
4.212IleThr: 4.212 ± 0.075
4.253IleVal: 4.253 ± 0.066
0.786IleTrp: 0.786 ± 0.03
2.168IleTyr: 2.168 ± 0.055
0.0IleXaa: 0.0 ± 0.0
Lys
4.167LysAla: 4.167 ± 0.076
0.308LysCys: 0.308 ± 0.021
2.585LysAsp: 2.585 ± 0.06
2.835LysGlu: 2.835 ± 0.065
1.468LysPhe: 1.468 ± 0.04
3.16LysGly: 3.16 ± 0.067
1.08LysHis: 1.08 ± 0.032
3.768LysIle: 3.768 ± 0.061
3.193LysLys: 3.193 ± 0.071
5.421LysLeu: 5.421 ± 0.077
1.621LysMet: 1.621 ± 0.038
2.735LysAsn: 2.735 ± 0.057
2.249LysPro: 2.249 ± 0.05
2.993LysGln: 2.993 ± 0.058
2.504LysArg: 2.504 ± 0.055
3.109LysSer: 3.109 ± 0.064
2.885LysThr: 2.885 ± 0.06
3.379LysVal: 3.379 ± 0.064
0.486LysTrp: 0.486 ± 0.023
1.53LysTyr: 1.53 ± 0.046
0.0LysXaa: 0.0 ± 0.0
Leu
10.056LeuAla: 10.056 ± 0.122
1.113LeuCys: 1.113 ± 0.032
5.402LeuAsp: 5.402 ± 0.079
5.315LeuGlu: 5.315 ± 0.089
4.338LeuPhe: 4.338 ± 0.089
6.787LeuGly: 6.787 ± 0.096
2.029LeuHis: 2.029 ± 0.051
7.574LeuIle: 7.574 ± 0.121
5.255LeuLys: 5.255 ± 0.081
11.408LeuLeu: 11.408 ± 0.181
2.76LeuMet: 2.76 ± 0.057
4.982LeuAsn: 4.982 ± 0.091
5.154LeuPro: 5.154 ± 0.088
4.135LeuGln: 4.135 ± 0.081
4.909LeuArg: 4.909 ± 0.085
8.107LeuSer: 8.107 ± 0.113
6.308LeuThr: 6.308 ± 0.098
6.377LeuVal: 6.377 ± 0.102
1.204LeuTrp: 1.204 ± 0.045
2.867LeuTyr: 2.867 ± 0.056
0.0LeuXaa: 0.0 ± 0.0
Met
2.542MetAla: 2.542 ± 0.055
0.195MetCys: 0.195 ± 0.014
1.22MetAsp: 1.22 ± 0.041
1.267MetGlu: 1.267 ± 0.041
0.86MetPhe: 0.86 ± 0.03
1.799MetGly: 1.799 ± 0.047
0.478MetHis: 0.478 ± 0.024
1.775MetIle: 1.775 ± 0.054
1.522MetLys: 1.522 ± 0.044
2.862MetLeu: 2.862 ± 0.067
0.82MetMet: 0.82 ± 0.033
1.251MetAsn: 1.251 ± 0.037
1.25MetPro: 1.25 ± 0.037
1.1MetGln: 1.1 ± 0.036
1.216MetArg: 1.216 ± 0.037
1.91MetSer: 1.91 ± 0.042
1.62MetThr: 1.62 ± 0.042
1.717MetVal: 1.717 ± 0.045
0.224MetTrp: 0.224 ± 0.016
0.557MetTyr: 0.557 ± 0.025
0.0MetXaa: 0.0 ± 0.0
Asn
3.415AsnAla: 3.415 ± 0.073
0.397AsnCys: 0.397 ± 0.022
2.339AsnAsp: 2.339 ± 0.049
2.463AsnGlu: 2.463 ± 0.056
1.684AsnPhe: 1.684 ± 0.042
2.968AsnGly: 2.968 ± 0.071
1.032AsnHis: 1.032 ± 0.039
3.806AsnIle: 3.806 ± 0.082
2.713AsnLys: 2.713 ± 0.066
4.203AsnLeu: 4.203 ± 0.084
1.131AsnMet: 1.131 ± 0.033
2.684AsnAsn: 2.684 ± 0.093
2.131AsnPro: 2.131 ± 0.051
2.516AsnGln: 2.516 ± 0.081
2.052AsnArg: 2.052 ± 0.051
3.017AsnSer: 3.017 ± 0.07
2.461AsnThr: 2.461 ± 0.072
2.448AsnVal: 2.448 ± 0.057
0.554AsnTrp: 0.554 ± 0.025
1.66AsnTyr: 1.66 ± 0.049
0.0AsnXaa: 0.0 ± 0.0
Pro
3.643ProAla: 3.643 ± 0.073
0.356ProCys: 0.356 ± 0.021
2.366ProAsp: 2.366 ± 0.048
3.293ProGlu: 3.293 ± 0.073
1.819ProPhe: 1.819 ± 0.048
2.498ProGly: 2.498 ± 0.055
0.939ProHis: 0.939 ± 0.037
2.752ProIle: 2.752 ± 0.052
1.86ProLys: 1.86 ± 0.043
4.613ProLeu: 4.613 ± 0.081
0.979ProMet: 0.979 ± 0.032
1.693ProAsn: 1.693 ± 0.05
1.362ProPro: 1.362 ± 0.036
2.094ProGln: 2.094 ± 0.053
1.586ProArg: 1.586 ± 0.037
2.401ProSer: 2.401 ± 0.064
2.251ProThr: 2.251 ± 0.054
3.039ProVal: 3.039 ± 0.054
0.567ProTrp: 0.567 ± 0.025
1.332ProTyr: 1.332 ± 0.039
0.0ProXaa: 0.0 ± 0.0
Gln
4.324GlnAla: 4.324 ± 0.086
0.396GlnCys: 0.396 ± 0.026
2.008GlnAsp: 2.008 ± 0.048
2.175GlnGlu: 2.175 ± 0.057
1.816GlnPhe: 1.816 ± 0.046
3.24GlnGly: 3.24 ± 0.082
1.371GlnHis: 1.371 ± 0.046
3.112GlnIle: 3.112 ± 0.058
2.392GlnLys: 2.392 ± 0.06
5.969GlnLeu: 5.969 ± 0.1
1.158GlnMet: 1.158 ± 0.034
1.747GlnAsn: 1.747 ± 0.042
2.227GlnPro: 2.227 ± 0.057
4.294GlnGln: 4.294 ± 0.124
2.911GlnArg: 2.911 ± 0.064
2.728GlnSer: 2.728 ± 0.065
2.146GlnThr: 2.146 ± 0.049
3.043GlnVal: 3.043 ± 0.059
0.701GlnTrp: 0.701 ± 0.031
1.53GlnTyr: 1.53 ± 0.044
0.0GlnXaa: 0.0 ± 0.0
Arg
3.367ArgAla: 3.367 ± 0.07
0.477ArgCys: 0.477 ± 0.025
2.508ArgAsp: 2.508 ± 0.057
3.015ArgGlu: 3.015 ± 0.076
2.232ArgPhe: 2.232 ± 0.052
2.783ArgGly: 2.783 ± 0.067
1.235ArgHis: 1.235 ± 0.038
3.383ArgIle: 3.383 ± 0.065
2.349ArgLys: 2.349 ± 0.053
5.331ArgLeu: 5.331 ± 0.087
1.22ArgMet: 1.22 ± 0.041
1.963ArgAsn: 1.963 ± 0.051
1.868ArgPro: 1.868 ± 0.052
2.74ArgGln: 2.74 ± 0.059
2.696ArgArg: 2.696 ± 0.071
2.521ArgSer: 2.521 ± 0.057
2.113ArgThr: 2.113 ± 0.045
2.962ArgVal: 2.962 ± 0.062
0.728ArgTrp: 0.728 ± 0.029
1.935ArgTyr: 1.935 ± 0.046
0.0ArgXaa: 0.0 ± 0.0
Ser
5.458SerAla: 5.458 ± 0.08
0.622SerCys: 0.622 ± 0.032
3.264SerAsp: 3.264 ± 0.062
3.519SerGlu: 3.519 ± 0.063
2.547SerPhe: 2.547 ± 0.06
5.103SerGly: 5.103 ± 0.086
1.515SerHis: 1.515 ± 0.046
4.477SerIle: 4.477 ± 0.084
2.697SerLys: 2.697 ± 0.055
7.3SerLeu: 7.3 ± 0.097
1.649SerMet: 1.649 ± 0.044
2.411SerAsn: 2.411 ± 0.065
2.648SerPro: 2.648 ± 0.072
3.174SerGln: 3.174 ± 0.059
2.938SerArg: 2.938 ± 0.055
4.048SerSer: 4.048 ± 0.071
3.229SerThr: 3.229 ± 0.068
4.208SerVal: 4.208 ± 0.063
0.917SerTrp: 0.917 ± 0.038
2.008SerTyr: 2.008 ± 0.051
0.0SerXaa: 0.0 ± 0.0
Thr
4.541ThrAla: 4.541 ± 0.074
0.498ThrCys: 0.498 ± 0.028
2.873ThrAsp: 2.873 ± 0.06
3.19ThrGlu: 3.19 ± 0.057
1.925ThrPhe: 1.925 ± 0.044
3.958ThrGly: 3.958 ± 0.071
1.257ThrHis: 1.257 ± 0.043
3.482ThrIle: 3.482 ± 0.065
2.124ThrLys: 2.124 ± 0.051
6.509ThrLeu: 6.509 ± 0.094
1.051ThrMet: 1.051 ± 0.037
1.945ThrAsn: 1.945 ± 0.049
2.885ThrPro: 2.885 ± 0.067
2.434ThrGln: 2.434 ± 0.067
2.404ThrArg: 2.404 ± 0.048
3.133ThrSer: 3.133 ± 0.058
2.774ThrThr: 2.774 ± 0.07
3.645ThrVal: 3.645 ± 0.064
0.519ThrTrp: 0.519 ± 0.023
1.433ThrTyr: 1.433 ± 0.043
0.0ThrXaa: 0.0 ± 0.0
Val
5.588ValAla: 5.588 ± 0.087
0.714ValCys: 0.714 ± 0.029
3.561ValAsp: 3.561 ± 0.067
3.614ValGlu: 3.614 ± 0.07
2.372ValPhe: 2.372 ± 0.053
4.395ValGly: 4.395 ± 0.084
1.069ValHis: 1.069 ± 0.042
5.262ValIle: 5.262 ± 0.096
3.266ValLys: 3.266 ± 0.063
6.182ValLeu: 6.182 ± 0.1
1.854ValMet: 1.854 ± 0.047
2.891ValAsn: 2.891 ± 0.061
2.515ValPro: 2.515 ± 0.056
2.079ValGln: 2.079 ± 0.051
2.81ValArg: 2.81 ± 0.063
4.319ValSer: 4.319 ± 0.072
3.855ValThr: 3.855 ± 0.061
4.356ValVal: 4.356 ± 0.082
0.744ValTrp: 0.744 ± 0.031
1.71ValTyr: 1.71 ± 0.044
0.0ValXaa: 0.0 ± 0.0
Trp
0.827TrpAla: 0.827 ± 0.029
0.158TrpCys: 0.158 ± 0.013
0.63TrpAsp: 0.63 ± 0.026
0.556TrpGlu: 0.556 ± 0.024
0.587TrpPhe: 0.587 ± 0.025
0.758TrpGly: 0.758 ± 0.029
0.342TrpHis: 0.342 ± 0.023
0.8TrpIle: 0.8 ± 0.032
0.525TrpLys: 0.525 ± 0.025
1.998TrpLeu: 1.998 ± 0.059
0.381TrpMet: 0.381 ± 0.021
0.439TrpAsn: 0.439 ± 0.022
0.495TrpPro: 0.495 ± 0.024
1.065TrpGln: 1.065 ± 0.038
0.752TrpArg: 0.752 ± 0.031
0.729TrpSer: 0.729 ± 0.034
0.426TrpThr: 0.426 ± 0.022
0.745TrpVal: 0.745 ± 0.029
0.178TrpTrp: 0.178 ± 0.014
0.359TrpTyr: 0.359 ± 0.022
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.317TyrAla: 2.317 ± 0.047
0.457TyrCys: 0.457 ± 0.022
1.62TyrAsp: 1.62 ± 0.05
1.364TyrGlu: 1.364 ± 0.039
1.539TyrPhe: 1.539 ± 0.045
2.224TyrGly: 2.224 ± 0.053
0.927TyrHis: 0.927 ± 0.032
2.004TyrIle: 2.004 ± 0.051
1.223TyrLys: 1.223 ± 0.036
3.551TyrLeu: 3.551 ± 0.063
0.654TyrMet: 0.654 ± 0.026
1.272TyrAsn: 1.272 ± 0.04
1.531TyrPro: 1.531 ± 0.042
2.165TyrGln: 2.165 ± 0.051
1.878TyrArg: 1.878 ± 0.05
2.077TyrSer: 2.077 ± 0.053
1.566TyrThr: 1.566 ± 0.043
1.655TyrVal: 1.655 ± 0.04
0.504TyrTrp: 0.504 ± 0.025
1.112TyrTyr: 1.112 ± 0.037
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2776 proteins (888818 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski