Amino acid dipepetide frequency for Carrot mottle mimic virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.885AlaAla: 4.885 ± 0.816
1.396AlaCys: 1.396 ± 1.029
4.187AlaAsp: 4.187 ± 1.248
3.489AlaGlu: 3.489 ± 1.78
3.489AlaPhe: 3.489 ± 2.17
7.676AlaGly: 7.676 ± 2.212
4.187AlaHis: 4.187 ± 2.249
1.396AlaIle: 1.396 ± 0.744
2.791AlaLys: 2.791 ± 2.058
9.072AlaLeu: 9.072 ± 1.731
2.791AlaMet: 2.791 ± 1.199
1.396AlaAsn: 1.396 ± 0.619
6.281AlaPro: 6.281 ± 1.699
2.094AlaGln: 2.094 ± 1.01
9.072AlaArg: 9.072 ± 2.909
7.676AlaSer: 7.676 ± 3.929
2.791AlaThr: 2.791 ± 1.971
6.281AlaVal: 6.281 ± 2.913
1.396AlaTrp: 1.396 ± 0.619
0.0AlaTyr: 0.0 ± 0.0
0.0AlaXaa: 0.0 ± 0.0
Cys
2.094CysAla: 2.094 ± 1.507
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
0.698CysGlu: 0.698 ± 0.514
0.698CysPhe: 0.698 ± 0.799
2.791CysGly: 2.791 ± 1.283
0.0CysHis: 0.0 ± 0.0
0.698CysIle: 0.698 ± 0.514
0.698CysLys: 0.698 ± 0.514
1.396CysLeu: 1.396 ± 1.246
0.698CysMet: 0.698 ± 0.354
0.0CysAsn: 0.0 ± 0.0
1.396CysPro: 1.396 ± 1.282
0.698CysGln: 0.698 ± 0.514
1.396CysArg: 1.396 ± 1.029
2.094CysSer: 2.094 ± 1.191
1.396CysThr: 1.396 ± 0.744
2.791CysVal: 2.791 ± 1.404
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
6.281AspAla: 6.281 ± 2.609
0.698AspCys: 0.698 ± 0.514
2.094AspAsp: 2.094 ± 1.262
2.791AspGlu: 2.791 ± 1.199
3.489AspPhe: 3.489 ± 0.893
4.885AspGly: 4.885 ± 0.445
0.698AspHis: 0.698 ± 0.738
0.698AspIle: 0.698 ± 0.514
3.489AspLys: 3.489 ± 0.987
4.187AspLeu: 4.187 ± 2.233
1.396AspMet: 1.396 ± 0.619
2.791AspAsn: 2.791 ± 1.283
4.885AspPro: 4.885 ± 1.674
0.698AspGln: 0.698 ± 0.514
0.698AspArg: 0.698 ± 0.514
2.094AspSer: 2.094 ± 0.579
4.885AspThr: 4.885 ± 1.303
2.791AspVal: 2.791 ± 1.283
2.094AspTrp: 2.094 ± 0.99
0.698AspTyr: 0.698 ± 0.799
0.0AspXaa: 0.0 ± 0.0
Glu
6.281GluAla: 6.281 ± 1.699
1.396GluCys: 1.396 ± 0.986
3.489GluAsp: 3.489 ± 0.987
1.396GluGlu: 1.396 ± 1.477
1.396GluPhe: 1.396 ± 1.029
5.583GluGly: 5.583 ± 2.398
2.094GluHis: 2.094 ± 0.999
1.396GluIle: 1.396 ± 0.619
3.489GluLys: 3.489 ± 1.685
4.885GluLeu: 4.885 ± 2.585
2.094GluMet: 2.094 ± 1.594
0.698GluAsn: 0.698 ± 0.738
6.281GluPro: 6.281 ± 2.405
3.489GluGln: 3.489 ± 1.079
5.583GluArg: 5.583 ± 1.432
1.396GluSer: 1.396 ± 0.744
1.396GluThr: 1.396 ± 1.477
4.187GluVal: 4.187 ± 0.958
0.0GluTrp: 0.0 ± 0.0
0.0GluTyr: 0.0 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
2.094PheAla: 2.094 ± 0.866
0.698PheCys: 0.698 ± 0.514
2.791PheAsp: 2.791 ± 1.283
2.094PheGlu: 2.094 ± 0.99
1.396PhePhe: 1.396 ± 0.921
4.187PheGly: 4.187 ± 0.582
0.0PheHis: 0.0 ± 0.0
2.094PheIle: 2.094 ± 0.999
0.698PheLys: 0.698 ± 0.514
5.583PheLeu: 5.583 ± 1.409
0.698PheMet: 0.698 ± 0.556
3.489PheAsn: 3.489 ± 2.572
0.698PhePro: 0.698 ± 0.514
0.698PheGln: 0.698 ± 0.514
0.698PheArg: 0.698 ± 0.514
3.489PheSer: 3.489 ± 1.111
2.094PheThr: 2.094 ± 0.999
1.396PheVal: 1.396 ± 0.619
0.0PheTrp: 0.0 ± 0.0
2.791PheTyr: 2.791 ± 0.594
0.0PheXaa: 0.0 ± 0.0
Gly
2.791GlyAla: 2.791 ± 1.099
2.094GlyCys: 2.094 ± 0.866
4.885GlyAsp: 4.885 ± 1.627
2.791GlyGlu: 2.791 ± 1.46
4.187GlyPhe: 4.187 ± 1.682
4.187GlyGly: 4.187 ± 1.93
0.698GlyHis: 0.698 ± 0.738
4.187GlyIle: 4.187 ± 0.916
0.698GlyLys: 0.698 ± 0.514
6.978GlyLeu: 6.978 ± 1.278
1.396GlyMet: 1.396 ± 1.029
2.094GlyAsn: 2.094 ± 0.99
5.583GlyPro: 5.583 ± 2.281
1.396GlyGln: 1.396 ± 0.657
7.676GlyArg: 7.676 ± 2.595
7.676GlySer: 7.676 ± 1.554
6.281GlyThr: 6.281 ± 1.463
4.885GlyVal: 4.885 ± 0.445
0.0GlyTrp: 0.0 ± 0.0
0.0GlyTyr: 0.0 ± 0.0
0.0GlyXaa: 0.0 ± 0.0
His
1.396HisAla: 1.396 ± 0.619
0.0HisCys: 0.0 ± 0.0
0.698HisAsp: 0.698 ± 0.799
2.094HisGlu: 2.094 ± 0.624
1.396HisPhe: 1.396 ± 0.657
0.698HisGly: 0.698 ± 0.799
0.0HisHis: 0.0 ± 0.0
1.396HisIle: 1.396 ± 0.619
0.0HisLys: 0.0 ± 0.0
1.396HisLeu: 1.396 ± 0.619
0.0HisMet: 0.0 ± 0.0
0.698HisAsn: 0.698 ± 0.514
2.791HisPro: 2.791 ± 0.918
2.094HisGln: 2.094 ± 1.558
0.698HisArg: 0.698 ± 0.641
2.791HisSer: 2.791 ± 0.513
2.791HisThr: 2.791 ± 0.716
1.396HisVal: 1.396 ± 0.744
0.0HisTrp: 0.0 ± 0.0
0.698HisTyr: 0.698 ± 0.799
0.0HisXaa: 0.0 ± 0.0
Ile
3.489IleAla: 3.489 ± 1.415
0.0IleCys: 0.0 ± 0.0
1.396IleAsp: 1.396 ± 1.029
1.396IleGlu: 1.396 ± 0.921
0.698IlePhe: 0.698 ± 0.514
2.791IleGly: 2.791 ± 0.918
0.0IleHis: 0.0 ± 0.0
2.094IleIle: 2.094 ± 0.999
2.094IleLys: 2.094 ± 1.543
1.396IleLeu: 1.396 ± 0.619
1.396IleMet: 1.396 ± 0.619
2.791IleAsn: 2.791 ± 1.404
5.583IlePro: 5.583 ± 1.835
3.489IleGln: 3.489 ± 1.19
3.489IleArg: 3.489 ± 1.111
0.0IleSer: 0.0 ± 0.0
2.791IleThr: 2.791 ± 1.199
1.396IleVal: 1.396 ± 0.744
0.0IleTrp: 0.0 ± 0.0
0.698IleTyr: 0.698 ± 0.514
0.0IleXaa: 0.0 ± 0.0
Lys
4.187LysAla: 4.187 ± 1.536
0.698LysCys: 0.698 ± 0.514
2.094LysAsp: 2.094 ± 0.866
3.489LysGlu: 3.489 ± 1.047
2.094LysPhe: 2.094 ± 1.262
1.396LysGly: 1.396 ± 1.029
0.698LysHis: 0.698 ± 0.514
1.396LysIle: 1.396 ± 1.029
0.698LysLys: 0.698 ± 0.514
2.094LysLeu: 2.094 ± 1.558
0.0LysMet: 0.0 ± 0.0
0.0LysAsn: 0.0 ± 0.0
3.489LysPro: 3.489 ± 1.915
0.0LysGln: 0.0 ± 0.0
2.791LysArg: 2.791 ± 1.404
0.0LysSer: 0.0 ± 0.0
2.094LysThr: 2.094 ± 0.579
4.187LysVal: 4.187 ± 1.406
1.396LysTrp: 1.396 ± 0.744
1.396LysTyr: 1.396 ± 1.029
0.0LysXaa: 0.0 ± 0.0
Leu
3.489LeuAla: 3.489 ± 0.893
2.791LeuCys: 2.791 ± 1.435
4.187LeuAsp: 4.187 ± 0.567
4.885LeuGlu: 4.885 ± 1.468
0.698LeuPhe: 0.698 ± 0.799
5.583LeuGly: 5.583 ± 1.847
2.791LeuHis: 2.791 ± 1.46
1.396LeuIle: 1.396 ± 0.921
2.791LeuLys: 2.791 ± 0.594
6.978LeuLeu: 6.978 ± 1.285
2.791LeuMet: 2.791 ± 1.283
3.489LeuAsn: 3.489 ± 0.191
6.281LeuPro: 6.281 ± 1.699
4.187LeuGln: 4.187 ± 2.377
3.489LeuArg: 3.489 ± 2.333
11.165LeuSer: 11.165 ± 3.37
4.885LeuThr: 4.885 ± 2.358
5.583LeuVal: 5.583 ± 1.588
1.396LeuTrp: 1.396 ± 0.986
4.885LeuTyr: 4.885 ± 1.734
0.0LeuXaa: 0.0 ± 0.0
Met
2.094MetAla: 2.094 ± 1.01
0.698MetCys: 0.698 ± 0.738
3.489MetAsp: 3.489 ± 1.415
4.187MetGlu: 4.187 ± 2.523
0.698MetPhe: 0.698 ± 0.641
0.0MetGly: 0.0 ± 0.0
0.0MetHis: 0.0 ± 0.0
0.0MetIle: 0.0 ± 0.0
0.698MetLys: 0.698 ± 0.514
1.396MetLeu: 1.396 ± 1.029
0.0MetMet: 0.0 ± 0.0
1.396MetAsn: 1.396 ± 0.892
1.396MetPro: 1.396 ± 1.477
1.396MetGln: 1.396 ± 0.619
0.0MetArg: 0.0 ± 0.0
0.698MetSer: 0.698 ± 0.514
1.396MetThr: 1.396 ± 0.619
2.094MetVal: 2.094 ± 1.543
0.698MetTrp: 0.698 ± 0.799
1.396MetTyr: 1.396 ± 0.657
0.0MetXaa: 0.0 ± 0.0
Asn
4.187AsnAla: 4.187 ± 0.958
1.396AsnCys: 1.396 ± 1.029
0.698AsnAsp: 0.698 ± 0.514
0.698AsnGlu: 0.698 ± 0.514
0.698AsnPhe: 0.698 ± 0.514
1.396AsnGly: 1.396 ± 0.657
0.0AsnHis: 0.0 ± 0.0
0.698AsnIle: 0.698 ± 0.738
0.0AsnLys: 0.0 ± 0.0
4.187AsnLeu: 4.187 ± 1.682
0.0AsnMet: 0.0 ± 0.0
2.094AsnAsn: 2.094 ± 0.624
3.489AsnPro: 3.489 ± 1.111
2.094AsnGln: 2.094 ± 0.624
3.489AsnArg: 3.489 ± 1.047
4.187AsnSer: 4.187 ± 1.227
2.791AsnThr: 2.791 ± 0.513
1.396AsnVal: 1.396 ± 0.657
0.0AsnTrp: 0.0 ± 0.0
1.396AsnTyr: 1.396 ± 0.921
0.0AsnXaa: 0.0 ± 0.0
Pro
7.676ProAla: 7.676 ± 2.588
0.698ProCys: 0.698 ± 0.514
2.791ProAsp: 2.791 ± 1.404
3.489ProGlu: 3.489 ± 2.404
0.0ProPhe: 0.0 ± 0.0
5.583ProGly: 5.583 ± 1.977
2.094ProHis: 2.094 ± 0.801
4.885ProIle: 4.885 ± 0.816
0.698ProLys: 0.698 ± 0.738
6.978ProLeu: 6.978 ± 2.331
1.396ProMet: 1.396 ± 1.029
2.094ProAsn: 2.094 ± 1.458
5.583ProPro: 5.583 ± 1.808
2.094ProGln: 2.094 ± 1.366
8.374ProArg: 8.374 ± 2.44
10.468ProSer: 10.468 ± 2.217
7.676ProThr: 7.676 ± 3.527
9.072ProVal: 9.072 ± 1.66
0.0ProTrp: 0.0 ± 0.0
1.396ProTyr: 1.396 ± 0.657
0.0ProXaa: 0.0 ± 0.0
Gln
4.187GlnAla: 4.187 ± 1.338
2.094GlnCys: 2.094 ± 0.624
1.396GlnAsp: 1.396 ± 0.921
1.396GlnGlu: 1.396 ± 1.477
1.396GlnPhe: 1.396 ± 0.619
0.698GlnGly: 0.698 ± 0.799
2.791GlnHis: 2.791 ± 0.594
3.489GlnIle: 3.489 ± 1.253
0.0GlnLys: 0.0 ± 0.0
1.396GlnLeu: 1.396 ± 0.744
1.396GlnMet: 1.396 ± 0.619
0.0GlnAsn: 0.0 ± 0.0
4.187GlnPro: 4.187 ± 1.97
1.396GlnGln: 1.396 ± 0.892
4.885GlnArg: 4.885 ± 2.215
2.094GlnSer: 2.094 ± 0.801
2.094GlnThr: 2.094 ± 0.999
0.698GlnVal: 0.698 ± 0.514
1.396GlnTrp: 1.396 ± 0.657
2.791GlnTyr: 2.791 ± 1.588
0.0GlnXaa: 0.0 ± 0.0
Arg
3.489ArgAla: 3.489 ± 2.42
0.698ArgCys: 0.698 ± 0.799
7.676ArgAsp: 7.676 ± 1.353
6.281ArgGlu: 6.281 ± 3.144
6.281ArgPhe: 6.281 ± 1.758
8.374ArgGly: 8.374 ± 1.957
2.094ArgHis: 2.094 ± 1.676
0.698ArgIle: 0.698 ± 0.514
2.791ArgLys: 2.791 ± 1.46
4.187ArgLeu: 4.187 ± 1.536
2.791ArgMet: 2.791 ± 1.238
2.791ArgAsn: 2.791 ± 1.313
6.978ArgPro: 6.978 ± 2.904
4.885ArgGln: 4.885 ± 0.816
6.978ArgArg: 6.978 ± 3.386
3.489ArgSer: 3.489 ± 2.019
1.396ArgThr: 1.396 ± 1.599
4.885ArgVal: 4.885 ± 2.128
1.396ArgTrp: 1.396 ± 0.619
1.396ArgTyr: 1.396 ± 0.657
0.0ArgXaa: 0.0 ± 0.0
Ser
8.374SerAla: 8.374 ± 2.076
0.0SerCys: 0.0 ± 0.0
2.791SerAsp: 2.791 ± 1.971
2.094SerGlu: 2.094 ± 1.366
2.791SerPhe: 2.791 ± 1.435
4.885SerGly: 4.885 ± 1.125
0.698SerHis: 0.698 ± 0.641
4.187SerIle: 4.187 ± 1.998
2.791SerLys: 2.791 ± 1.103
7.676SerLeu: 7.676 ± 4.373
2.791SerMet: 2.791 ± 1.099
1.396SerAsn: 1.396 ± 0.986
6.281SerPro: 6.281 ± 2.651
2.094SerGln: 2.094 ± 1.456
6.281SerArg: 6.281 ± 1.872
6.281SerSer: 6.281 ± 2.758
4.187SerThr: 4.187 ± 1.666
5.583SerVal: 5.583 ± 0.546
1.396SerTrp: 1.396 ± 0.657
2.094SerTyr: 2.094 ± 0.866
0.0SerXaa: 0.0 ± 0.0
Thr
6.978ThrAla: 6.978 ± 3.08
1.396ThrCys: 1.396 ± 0.744
2.094ThrAsp: 2.094 ± 0.866
4.187ThrGlu: 4.187 ± 0.736
0.698ThrPhe: 0.698 ± 0.514
4.187ThrGly: 4.187 ± 1.73
1.396ThrHis: 1.396 ± 1.029
1.396ThrIle: 1.396 ± 0.892
3.489ThrLys: 3.489 ± 1.111
3.489ThrLeu: 3.489 ± 1.854
0.698ThrMet: 0.698 ± 0.514
2.791ThrAsn: 2.791 ± 1.469
4.885ThrPro: 4.885 ± 1.594
2.791ThrGln: 2.791 ± 0.594
6.978ThrArg: 6.978 ± 2.525
2.094ThrSer: 2.094 ± 1.01
3.489ThrThr: 3.489 ± 1.891
4.885ThrVal: 4.885 ± 2.227
0.698ThrTrp: 0.698 ± 0.738
0.0ThrTyr: 0.0 ± 0.0
0.0ThrXaa: 0.0 ± 0.0
Val
6.978ValAla: 6.978 ± 3.08
2.094ValCys: 2.094 ± 0.99
4.187ValAsp: 4.187 ± 1.857
6.978ValGlu: 6.978 ± 2.314
4.187ValPhe: 4.187 ± 2.242
3.489ValGly: 3.489 ± 0.987
2.094ValHis: 2.094 ± 0.866
4.187ValIle: 4.187 ± 1.406
3.489ValLys: 3.489 ± 1.753
4.187ValLeu: 4.187 ± 1.159
0.0ValMet: 0.0 ± 0.0
4.187ValAsn: 4.187 ± 1.733
3.489ValPro: 3.489 ± 1.111
2.094ValGln: 2.094 ± 0.999
4.187ValArg: 4.187 ± 1.998
4.187ValSer: 4.187 ± 1.682
2.094ValThr: 2.094 ± 0.801
5.583ValVal: 5.583 ± 0.56
0.0ValTrp: 0.0 ± 0.0
2.791ValTyr: 2.791 ± 0.716
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.698TrpCys: 0.698 ± 0.641
0.698TrpAsp: 0.698 ± 0.514
0.698TrpGlu: 0.698 ± 0.514
0.698TrpPhe: 0.698 ± 0.514
1.396TrpGly: 1.396 ± 0.892
0.698TrpHis: 0.698 ± 0.514
0.0TrpIle: 0.0 ± 0.0
0.0TrpLys: 0.0 ± 0.0
2.791TrpLeu: 2.791 ± 1.246
0.0TrpMet: 0.0 ± 0.0
0.698TrpAsn: 0.698 ± 0.799
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
1.396TrpArg: 1.396 ± 0.744
0.698TrpSer: 0.698 ± 0.514
0.0TrpThr: 0.0 ± 0.0
0.698TrpVal: 0.698 ± 0.738
0.698TrpTrp: 0.698 ± 0.514
0.698TrpTyr: 0.698 ± 0.738
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.396TyrAla: 1.396 ± 0.986
0.0TyrCys: 0.0 ± 0.0
0.698TyrAsp: 0.698 ± 0.514
2.094TyrGlu: 2.094 ± 0.866
0.698TyrPhe: 0.698 ± 0.514
0.698TyrGly: 0.698 ± 0.641
0.0TyrHis: 0.0 ± 0.0
0.698TyrIle: 0.698 ± 0.514
2.791TyrLys: 2.791 ± 2.058
3.489TyrLeu: 3.489 ± 1.824
0.698TyrMet: 0.698 ± 0.816
0.0TyrAsn: 0.0 ± 0.0
3.489TyrPro: 3.489 ± 1.721
2.094TyrGln: 2.094 ± 0.999
1.396TyrArg: 1.396 ± 0.657
2.094TyrSer: 2.094 ± 1.01
2.094TyrThr: 2.094 ± 0.866
0.698TyrVal: 0.698 ± 0.514
0.0TyrTrp: 0.0 ± 0.0
0.698TyrTyr: 0.698 ± 0.738
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4 proteins (1434 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski