Amino acid dipepetide frequency for Sinimarinibacterium sp. CAU 1509

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	16.499AlaAla: 16.499 ± 0.163	1.351AlaCys: 1.351 ± 0.036	6.979AlaAsp: 6.979 ± 0.077	7.059AlaGlu: 7.059 ± 0.076	3.751AlaPhe: 3.751 ± 0.052	9.654AlaGly: 9.654 ± 0.104	2.486AlaHis: 2.486 ± 0.038	5.395AlaIle: 5.395 ± 0.066	3.081AlaLys: 3.081 ± 0.058	13.989AlaLeu: 13.989 ± 0.121	3.099AlaMet: 3.099 ± 0.047	2.685AlaAsn: 2.685 ± 0.048	5.883AlaPro: 5.883 ± 0.089	5.501AlaGln: 5.501 ± 0.07	8.465AlaArg: 8.465 ± 0.103	6.312AlaSer: 6.312 ± 0.073	5.738AlaThr: 5.738 ± 0.079	8.895AlaVal: 8.895 ± 0.09	1.706AlaTrp: 1.706 ± 0.042	2.775AlaTyr: 2.775 ± 0.042	0.0AlaXaa: 0.0 ± 0.0
Cys	1.349CysAla: 1.349 ± 0.035	0.154CysCys: 0.154 ± 0.011	0.608CysAsp: 0.608 ± 0.022	0.577CysGlu: 0.577 ± 0.023	0.307CysPhe: 0.307 ± 0.013	1.109CysGly: 1.109 ± 0.029	0.358CysHis: 0.358 ± 0.034	0.435CysIle: 0.435 ± 0.018	0.257CysLys: 0.257 ± 0.014	0.916CysLeu: 0.916 ± 0.026	0.208CysMet: 0.208 ± 0.012	0.265CysAsn: 0.265 ± 0.016	0.557CysPro: 0.557 ± 0.022	0.239CysGln: 0.239 ± 0.013	0.703CysArg: 0.703 ± 0.027	0.646CysSer: 0.646 ± 0.024	0.533CysThr: 0.533 ± 0.019	0.797CysVal: 0.797 ± 0.028	0.143CysTrp: 0.143 ± 0.009	0.226CysTyr: 0.226 ± 0.013	0.0CysXaa: 0.0 ± 0.0
Asp	8.151AspAla: 8.151 ± 0.078	0.589AspCys: 0.589 ± 0.024	3.495AspAsp: 3.495 ± 0.053	3.223AspGlu: 3.223 ± 0.047	2.126AspPhe: 2.126 ± 0.042	5.344AspGly: 5.344 ± 0.077	1.249AspHis: 1.249 ± 0.034	2.553AspIle: 2.553 ± 0.046	1.435AspLys: 1.435 ± 0.037	5.706AspLeu: 5.706 ± 0.063	1.077AspMet: 1.077 ± 0.029	1.341AspAsn: 1.341 ± 0.034	3.599AspPro: 3.599 ± 0.056	1.996AspGln: 1.996 ± 0.039	3.837AspArg: 3.837 ± 0.056	2.806AspSer: 2.806 ± 0.045	2.84AspThr: 2.84 ± 0.044	4.259AspVal: 4.259 ± 0.054	1.039AspTrp: 1.039 ± 0.028	1.701AspTyr: 1.701 ± 0.036	0.0AspXaa: 0.0 ± 0.0
Glu	6.405GluAla: 6.405 ± 0.069	0.511GluCys: 0.511 ± 0.017	2.46GluAsp: 2.46 ± 0.048	2.212GluGlu: 2.212 ± 0.042	1.957GluPhe: 1.957 ± 0.04	3.452GluGly: 3.452 ± 0.048	1.454GluHis: 1.454 ± 0.031	2.889GluIle: 2.889 ± 0.05	1.599GluLys: 1.599 ± 0.041	6.108GluLeu: 6.108 ± 0.087	1.248GluMet: 1.248 ± 0.031	1.298GluAsn: 1.298 ± 0.031	2.554GluPro: 2.554 ± 0.05	2.783GluGln: 2.783 ± 0.047	4.974GluArg: 4.974 ± 0.075	2.964GluSer: 2.964 ± 0.044	2.848GluThr: 2.848 ± 0.047	3.904GluVal: 3.904 ± 0.054	0.734GluTrp: 0.734 ± 0.025	1.293GluTyr: 1.293 ± 0.03	0.0GluXaa: 0.0 ± 0.0
Phe	4.04PheAla: 4.04 ± 0.063	0.396PheCys: 0.396 ± 0.018	2.535PheAsp: 2.535 ± 0.046	2.13PheGlu: 2.13 ± 0.045	1.243PhePhe: 1.243 ± 0.035	3.422PheGly: 3.422 ± 0.055	0.707PheHis: 0.707 ± 0.025	1.406PheIle: 1.406 ± 0.029	0.978PheLys: 0.978 ± 0.029	2.909PheLeu: 2.909 ± 0.053	0.767PheMet: 0.767 ± 0.026	1.138PheAsn: 1.138 ± 0.031	1.553PhePro: 1.553 ± 0.031	0.962PheGln: 0.962 ± 0.029	2.164PheArg: 2.164 ± 0.045	2.158PheSer: 2.158 ± 0.041	1.814PheThr: 1.814 ± 0.037	2.709PheVal: 2.709 ± 0.039	0.485PheTrp: 0.485 ± 0.021	0.872PheTyr: 0.872 ± 0.027	0.0PheXaa: 0.0 ± 0.0
Gly	8.77GlyAla: 8.77 ± 0.094	0.991GlyCys: 0.991 ± 0.032	4.579GlyAsp: 4.579 ± 0.061	4.264GlyGlu: 4.264 ± 0.059	3.275GlyPhe: 3.275 ± 0.049	6.925GlyGly: 6.925 ± 0.098	1.946GlyHis: 1.946 ± 0.037	4.157GlyIle: 4.157 ± 0.067	2.689GlyLys: 2.689 ± 0.053	8.365GlyLeu: 8.365 ± 0.082	2.079GlyMet: 2.079 ± 0.044	2.15GlyAsn: 2.15 ± 0.047	3.01GlyPro: 3.01 ± 0.05	2.839GlyGln: 2.839 ± 0.044	5.469GlyArg: 5.469 ± 0.078	4.899GlySer: 4.899 ± 0.081	4.389GlyThr: 4.389 ± 0.068	6.604GlyVal: 6.604 ± 0.081	1.33GlyTrp: 1.33 ± 0.035	2.497GlyTyr: 2.497 ± 0.046	0.0GlyXaa: 0.0 ± 0.0
His	2.765HisAla: 2.765 ± 0.049	0.31HisCys: 0.31 ± 0.017	1.247HisAsp: 1.247 ± 0.029	1.108HisGlu: 1.108 ± 0.033	0.887HisPhe: 0.887 ± 0.029	2.026HisGly: 2.026 ± 0.038	0.703HisHis: 0.703 ± 0.024	0.9HisIle: 0.9 ± 0.026	0.496HisLys: 0.496 ± 0.019	2.346HisLeu: 2.346 ± 0.05	0.468HisMet: 0.468 ± 0.02	0.516HisAsn: 0.516 ± 0.022	1.519HisPro: 1.519 ± 0.031	0.83HisGln: 0.83 ± 0.023	1.697HisArg: 1.697 ± 0.039	1.185HisSer: 1.185 ± 0.03	1.026HisThr: 1.026 ± 0.029	1.462HisVal: 1.462 ± 0.03	0.459HisTrp: 0.459 ± 0.017	0.703HisTyr: 0.703 ± 0.023	0.0HisXaa: 0.0 ± 0.0
Ile	6.246IleAla: 6.246 ± 0.07	0.483IleCys: 0.483 ± 0.022	3.603IleAsp: 3.603 ± 0.052	3.508IleGlu: 3.508 ± 0.051	1.316IlePhe: 1.316 ± 0.029	4.377IleGly: 4.377 ± 0.065	0.97IleHis: 0.97 ± 0.026	1.571IleIle: 1.571 ± 0.037	1.354IleLys: 1.354 ± 0.041	3.514IleLeu: 3.514 ± 0.054	0.703IleMet: 0.703 ± 0.024	1.521IleAsn: 1.521 ± 0.037	2.31IlePro: 2.31 ± 0.041	1.427IleGln: 1.427 ± 0.035	3.065IleArg: 3.065 ± 0.048	2.555IleSer: 2.555 ± 0.048	2.449IleThr: 2.449 ± 0.046	3.683IleVal: 3.683 ± 0.055	0.556IleTrp: 0.556 ± 0.018	1.091IleTyr: 1.091 ± 0.031	0.0IleXaa: 0.0 ± 0.0
Lys	3.296LysAla: 3.296 ± 0.067	0.19LysCys: 0.19 ± 0.012	1.465LysAsp: 1.465 ± 0.038	1.183LysGlu: 1.183 ± 0.038	0.824LysPhe: 0.824 ± 0.025	1.871LysGly: 1.871 ± 0.045	0.581LysHis: 0.581 ± 0.021	1.418LysIle: 1.418 ± 0.039	1.057LysLys: 1.057 ± 0.042	3.235LysLeu: 3.235 ± 0.063	0.658LysMet: 0.658 ± 0.022	0.728LysAsn: 0.728 ± 0.023	1.801LysPro: 1.801 ± 0.04	1.241LysGln: 1.241 ± 0.033	2.103LysArg: 2.103 ± 0.041	1.538LysSer: 1.538 ± 0.031	1.718LysThr: 1.718 ± 0.04	2.082LysVal: 2.082 ± 0.048	0.31LysTrp: 0.31 ± 0.016	0.644LysTyr: 0.644 ± 0.023	0.0LysXaa: 0.0 ± 0.0
Leu	12.557LeuAla: 12.557 ± 0.118	1.123LeuCys: 1.123 ± 0.027	6.454LeuAsp: 6.454 ± 0.064	5.38LeuGlu: 5.38 ± 0.073	3.479LeuPhe: 3.479 ± 0.055	8.483LeuGly: 8.483 ± 0.09	2.349LeuHis: 2.349 ± 0.045	4.867LeuIle: 4.867 ± 0.064	3.347LeuLys: 3.347 ± 0.058	11.311LeuLeu: 11.311 ± 0.133	2.495LeuMet: 2.495 ± 0.039	2.898LeuAsn: 2.898 ± 0.048	6.01LeuPro: 6.01 ± 0.076	4.331LeuGln: 4.331 ± 0.061	8.481LeuArg: 8.481 ± 0.108	6.86LeuSer: 6.86 ± 0.084	5.353LeuThr: 5.353 ± 0.064	6.826LeuVal: 6.826 ± 0.087	1.386LeuTrp: 1.386 ± 0.034	2.286LeuTyr: 2.286 ± 0.044	0.0LeuXaa: 0.0 ± 0.0
Met	2.568MetAla: 2.568 ± 0.044	0.194MetCys: 0.194 ± 0.013	1.098MetAsp: 1.098 ± 0.029	0.955MetGlu: 0.955 ± 0.029	0.7MetPhe: 0.7 ± 0.023	1.568MetGly: 1.568 ± 0.035	0.531MetHis: 0.531 ± 0.018	1.065MetIle: 1.065 ± 0.032	0.854MetLys: 0.854 ± 0.025	2.551MetLeu: 2.551 ± 0.048	0.557MetMet: 0.557 ± 0.023	0.867MetAsn: 0.867 ± 0.025	1.39MetPro: 1.39 ± 0.038	1.058MetGln: 1.058 ± 0.028	1.88MetArg: 1.88 ± 0.037	1.677MetSer: 1.677 ± 0.036	1.505MetThr: 1.505 ± 0.034	1.475MetVal: 1.475 ± 0.036	0.194MetTrp: 0.194 ± 0.011	0.434MetTyr: 0.434 ± 0.018	0.0MetXaa: 0.0 ± 0.0
Asn	3.149AsnAla: 3.149 ± 0.048	0.278AsnCys: 0.278 ± 0.016	1.532AsnAsp: 1.532 ± 0.037	1.189AsnGlu: 1.189 ± 0.03	0.935AsnPhe: 0.935 ± 0.027	2.304AsnGly: 2.304 ± 0.053	0.558AsnHis: 0.558 ± 0.021	1.169AsnIle: 1.169 ± 0.029	0.676AsnLys: 0.676 ± 0.024	2.762AsnLeu: 2.762 ± 0.042	0.494AsnMet: 0.494 ± 0.017	0.764AsnAsn: 0.764 ± 0.032	1.868AsnPro: 1.868 ± 0.039	0.961AsnGln: 0.961 ± 0.027	1.716AsnArg: 1.716 ± 0.036	1.295AsnSer: 1.295 ± 0.033	1.429AsnThr: 1.429 ± 0.035	1.911AsnVal: 1.911 ± 0.04	0.401AsnTrp: 0.401 ± 0.017	0.725AsnTyr: 0.725 ± 0.024	0.0AsnXaa: 0.0 ± 0.0
Pro	6.409ProAla: 6.409 ± 0.085	0.367ProCys: 0.367 ± 0.016	3.648ProAsp: 3.648 ± 0.058	3.651ProGlu: 3.651 ± 0.061	1.718ProPhe: 1.718 ± 0.035	4.386ProGly: 4.386 ± 0.06	1.042ProHis: 1.042 ± 0.029	2.122ProIle: 2.122 ± 0.045	1.461ProLys: 1.461 ± 0.036	5.236ProLeu: 5.236 ± 0.069	1.362ProMet: 1.362 ± 0.034	1.325ProAsn: 1.325 ± 0.033	2.722ProPro: 2.722 ± 0.052	2.396ProGln: 2.396 ± 0.046	3.078ProArg: 3.078 ± 0.049	2.92ProSer: 2.92 ± 0.049	2.731ProThr: 2.731 ± 0.055	4.117ProVal: 4.117 ± 0.057	0.705ProTrp: 0.705 ± 0.024	1.258ProTyr: 1.258 ± 0.033	0.0ProXaa: 0.0 ± 0.0
Gln	4.903GlnAla: 4.903 ± 0.083	0.366GlnCys: 0.366 ± 0.017	1.683GlnAsp: 1.683 ± 0.036	1.384GlnGlu: 1.384 ± 0.032	1.351GlnPhe: 1.351 ± 0.031	2.559GlnGly: 2.559 ± 0.043	0.99GlnHis: 0.99 ± 0.029	2.126GlnIle: 2.126 ± 0.039	1.04GlnLys: 1.04 ± 0.027	4.685GlnLeu: 4.685 ± 0.069	0.999GlnMet: 0.999 ± 0.029	0.889GlnAsn: 0.889 ± 0.027	2.102GlnPro: 2.102 ± 0.041	2.145GlnGln: 2.145 ± 0.046	3.71GlnArg: 3.71 ± 0.06	2.133GlnSer: 2.133 ± 0.043	2.157GlnThr: 2.157 ± 0.041	2.824GlnVal: 2.824 ± 0.046	0.698GlnTrp: 0.698 ± 0.026	0.904GlnTyr: 0.904 ± 0.029	0.0GlnXaa: 0.0 ± 0.0
Arg	7.887ArgAla: 7.887 ± 0.089	0.734ArgCys: 0.734 ± 0.025	4.046ArgAsp: 4.046 ± 0.057	4.259ArgGlu: 4.259 ± 0.057	2.725ArgPhe: 2.725 ± 0.052	4.929ArgGly: 4.929 ± 0.068	1.839ArgHis: 1.839 ± 0.039	3.966ArgIle: 3.966 ± 0.06	2.098ArgLys: 2.098 ± 0.04	8.018ArgLeu: 8.018 ± 0.09	1.933ArgMet: 1.933 ± 0.037	1.965ArgAsn: 1.965 ± 0.036	3.247ArgPro: 3.247 ± 0.057	2.838ArgGln: 2.838 ± 0.053	5.757ArgArg: 5.757 ± 0.082	4.138ArgSer: 4.138 ± 0.06	3.331ArgThr: 3.331 ± 0.046	5.399ArgVal: 5.399 ± 0.078	1.275ArgTrp: 1.275 ± 0.036	2.425ArgTyr: 2.425 ± 0.044	0.0ArgXaa: 0.0 ± 0.0
Ser	6.94SerAla: 6.94 ± 0.077	0.597SerCys: 0.597 ± 0.03	3.305SerAsp: 3.305 ± 0.05	2.935SerGlu: 2.935 ± 0.05	1.949SerPhe: 1.949 ± 0.039	5.752SerGly: 5.752 ± 0.083	1.15SerHis: 1.15 ± 0.03	2.574SerIle: 2.574 ± 0.048	1.551SerLys: 1.551 ± 0.035	5.768SerLeu: 5.768 ± 0.066	1.355SerMet: 1.355 ± 0.03	1.536SerAsn: 1.536 ± 0.032	2.917SerPro: 2.917 ± 0.055	1.841SerGln: 1.841 ± 0.036	3.69SerArg: 3.69 ± 0.052	3.421SerSer: 3.421 ± 0.066	3.113SerThr: 3.113 ± 0.056	4.397SerVal: 4.397 ± 0.065	0.847SerTrp: 0.847 ± 0.027	1.427SerTyr: 1.427 ± 0.035	0.0SerXaa: 0.0 ± 0.0
Thr	6.469ThrAla: 6.469 ± 0.088	0.452ThrCys: 0.452 ± 0.021	2.81ThrAsp: 2.81 ± 0.049	2.546ThrGlu: 2.546 ± 0.042	1.617ThrPhe: 1.617 ± 0.032	4.409ThrGly: 4.409 ± 0.058	1.225ThrHis: 1.225 ± 0.034	2.24ThrIle: 2.24 ± 0.042	1.074ThrLys: 1.074 ± 0.031	6.261ThrLeu: 6.261 ± 0.067	1.039ThrMet: 1.039 ± 0.027	1.056ThrAsn: 1.056 ± 0.028	3.745ThrPro: 3.745 ± 0.065	2.116ThrGln: 2.116 ± 0.038	3.551ThrArg: 3.551 ± 0.053	2.664ThrSer: 2.664 ± 0.051	2.794ThrThr: 2.794 ± 0.057	4.197ThrVal: 4.197 ± 0.065	0.666ThrTrp: 0.666 ± 0.021	1.206ThrTyr: 1.206 ± 0.035	0.0ThrXaa: 0.0 ± 0.0
Val	8.681ValAla: 8.681 ± 0.091	0.84ValCys: 0.84 ± 0.024	4.57ValAsp: 4.57 ± 0.068	4.323ValGlu: 4.323 ± 0.064	2.645ValPhe: 2.645 ± 0.047	5.478ValGly: 5.478 ± 0.079	1.585ValHis: 1.585 ± 0.032	3.721ValIle: 3.721 ± 0.056	1.893ValLys: 1.893 ± 0.05	8.021ValLeu: 8.021 ± 0.089	1.733ValMet: 1.733 ± 0.032	2.013ValAsn: 2.013 ± 0.043	3.944ValPro: 3.944 ± 0.061	2.504ValGln: 2.504 ± 0.044	5.122ValArg: 5.122 ± 0.07	4.517ValSer: 4.517 ± 0.063	4.154ValThr: 4.154 ± 0.072	5.88ValVal: 5.88 ± 0.077	0.981ValTrp: 0.981 ± 0.028	1.642ValTyr: 1.642 ± 0.033	0.0ValXaa: 0.0 ± 0.0
Trp	1.309TrpAla: 1.309 ± 0.033	0.178TrpCys: 0.178 ± 0.011	0.707TrpAsp: 0.707 ± 0.021	0.529TrpGlu: 0.529 ± 0.019	0.544TrpPhe: 0.544 ± 0.019	0.933TrpGly: 0.933 ± 0.029	0.403TrpHis: 0.403 ± 0.018	0.808TrpIle: 0.808 ± 0.026	0.388TrpLys: 0.388 ± 0.017	1.959TrpLeu: 1.959 ± 0.042	0.41TrpMet: 0.41 ± 0.016	0.468TrpAsn: 0.468 ± 0.019	0.7TrpPro: 0.7 ± 0.024	0.661TrpGln: 0.661 ± 0.02	1.193TrpArg: 1.193 ± 0.031	0.945TrpSer: 0.945 ± 0.024	0.871TrpThr: 0.871 ± 0.028	1.0TrpVal: 1.0 ± 0.028	0.253TrpTrp: 0.253 ± 0.013	0.327TrpTyr: 0.327 ± 0.015	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.908TyrAla: 2.908 ± 0.043	0.283TyrCys: 0.283 ± 0.016	1.54TyrAsp: 1.54 ± 0.04	1.233TyrGlu: 1.233 ± 0.029	1.038TyrPhe: 1.038 ± 0.028	2.247TyrGly: 2.247 ± 0.044	0.525TyrHis: 0.525 ± 0.021	0.921TyrIle: 0.921 ± 0.027	0.617TyrLys: 0.617 ± 0.025	2.616TyrLeu: 2.616 ± 0.048	0.439TyrMet: 0.439 ± 0.018	0.69TyrAsn: 0.69 ± 0.025	1.224TyrPro: 1.224 ± 0.03	0.978TyrGln: 0.978 ± 0.028	2.153TyrArg: 2.153 ± 0.048	1.433TyrSer: 1.433 ± 0.032	1.343TyrThr: 1.343 ± 0.033	1.828TyrVal: 1.828 ± 0.045	0.418TyrTrp: 0.418 ± 0.017	0.693TyrTyr: 0.693 ± 0.024	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4153 proteins (1371815 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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