Amino acid dipepetide frequency for Paraburkholderia susongensis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	17.648AlaAla: 17.648 ± 0.158	1.312AlaCys: 1.312 ± 0.029	6.373AlaAsp: 6.373 ± 0.064	5.871AlaGlu: 5.871 ± 0.065	4.324AlaPhe: 4.324 ± 0.053	10.392AlaGly: 10.392 ± 0.079	2.887AlaHis: 2.887 ± 0.037	5.864AlaIle: 5.864 ± 0.05	3.647AlaLys: 3.647 ± 0.049	14.167AlaLeu: 14.167 ± 0.11	3.243AlaMet: 3.243 ± 0.049	3.44AlaAsn: 3.44 ± 0.051	5.822AlaPro: 5.822 ± 0.066	5.505AlaGln: 5.505 ± 0.064	8.912AlaArg: 8.912 ± 0.089	7.644AlaSer: 7.644 ± 0.078	6.42AlaThr: 6.42 ± 0.069	8.705AlaVal: 8.705 ± 0.076	1.683AlaTrp: 1.683 ± 0.031	2.748AlaTyr: 2.748 ± 0.037	0.0AlaXaa: 0.0 ± 0.0
Cys	1.282CysAla: 1.282 ± 0.026	0.127CysCys: 0.127 ± 0.007	0.57CysAsp: 0.57 ± 0.019	0.51CysGlu: 0.51 ± 0.015	0.351CysPhe: 0.351 ± 0.013	1.041CysGly: 1.041 ± 0.024	0.25CysHis: 0.25 ± 0.01	0.423CysIle: 0.423 ± 0.015	0.214CysLys: 0.214 ± 0.011	0.827CysLeu: 0.827 ± 0.021	0.212CysMet: 0.212 ± 0.01	0.252CysAsn: 0.252 ± 0.012	0.427CysPro: 0.427 ± 0.016	0.226CysGln: 0.226 ± 0.01	0.595CysArg: 0.595 ± 0.017	0.52CysSer: 0.52 ± 0.017	0.498CysThr: 0.498 ± 0.016	0.831CysVal: 0.831 ± 0.02	0.125CysTrp: 0.125 ± 0.007	0.229CysTyr: 0.229 ± 0.009	0.0CysXaa: 0.0 ± 0.0
Asp	7.399AspAla: 7.399 ± 0.074	0.455AspCys: 0.455 ± 0.014	3.012AspAsp: 3.012 ± 0.039	3.34AspGlu: 3.34 ± 0.046	1.945AspPhe: 1.945 ± 0.03	4.507AspGly: 4.507 ± 0.057	1.129AspHis: 1.129 ± 0.027	2.531AspIle: 2.531 ± 0.036	1.417AspLys: 1.417 ± 0.03	4.978AspLeu: 4.978 ± 0.055	1.221AspMet: 1.221 ± 0.021	1.345AspAsn: 1.345 ± 0.029	2.863AspPro: 2.863 ± 0.036	1.507AspGln: 1.507 ± 0.028	3.106AspArg: 3.106 ± 0.043	2.593AspSer: 2.593 ± 0.037	2.879AspThr: 2.879 ± 0.041	4.26AspVal: 4.26 ± 0.056	0.886AspTrp: 0.886 ± 0.023	1.524AspTyr: 1.524 ± 0.027	0.0AspXaa: 0.0 ± 0.0
Glu	6.425GluAla: 6.425 ± 0.079	0.422GluCys: 0.422 ± 0.016	2.076GluAsp: 2.076 ± 0.031	2.351GluGlu: 2.351 ± 0.043	1.792GluPhe: 1.792 ± 0.031	3.274GluGly: 3.274 ± 0.039	1.504GluHis: 1.504 ± 0.024	2.76GluIle: 2.76 ± 0.04	1.787GluLys: 1.787 ± 0.033	5.44GluLeu: 5.44 ± 0.057	1.225GluMet: 1.225 ± 0.026	1.472GluAsn: 1.472 ± 0.026	2.593GluPro: 2.593 ± 0.039	2.345GluGln: 2.345 ± 0.04	4.92GluArg: 4.92 ± 0.066	2.625GluSer: 2.625 ± 0.03	2.849GluThr: 2.849 ± 0.037	3.521GluVal: 3.521 ± 0.042	0.752GluTrp: 0.752 ± 0.018	1.141GluTyr: 1.141 ± 0.026	0.0GluXaa: 0.0 ± 0.0
Phe	4.762PheAla: 4.762 ± 0.051	0.434PheCys: 0.434 ± 0.017	2.71PheAsp: 2.71 ± 0.039	2.075PheGlu: 2.075 ± 0.031	1.523PhePhe: 1.523 ± 0.029	3.809PheGly: 3.809 ± 0.046	0.774PheHis: 0.774 ± 0.019	1.679PheIle: 1.679 ± 0.03	0.977PheLys: 0.977 ± 0.02	3.029PheLeu: 3.029 ± 0.046	0.827PheMet: 0.827 ± 0.019	1.219PheAsn: 1.219 ± 0.026	1.608PhePro: 1.608 ± 0.03	0.977PheGln: 0.977 ± 0.024	2.065PheArg: 2.065 ± 0.031	2.392PheSer: 2.392 ± 0.034	1.992PheThr: 1.992 ± 0.031	3.154PheVal: 3.154 ± 0.042	0.507PheTrp: 0.507 ± 0.018	0.974PheTyr: 0.974 ± 0.022	0.0PheXaa: 0.0 ± 0.0
Gly	9.582GlyAla: 9.582 ± 0.08	0.872GlyCys: 0.872 ± 0.023	3.772GlyAsp: 3.772 ± 0.047	4.344GlyGlu: 4.344 ± 0.05	3.485GlyPhe: 3.485 ± 0.045	6.784GlyGly: 6.784 ± 0.083	1.915GlyHis: 1.915 ± 0.03	4.349GlyIle: 4.349 ± 0.046	3.155GlyLys: 3.155 ± 0.042	8.069GlyLeu: 8.069 ± 0.068	2.306GlyMet: 2.306 ± 0.035	2.458GlyAsn: 2.458 ± 0.037	2.91GlyPro: 2.91 ± 0.036	2.75GlyGln: 2.75 ± 0.039	5.182GlyArg: 5.182 ± 0.054	4.71GlySer: 4.71 ± 0.059	4.69GlyThr: 4.69 ± 0.063	6.797GlyVal: 6.797 ± 0.068	1.375GlyTrp: 1.375 ± 0.032	2.438GlyTyr: 2.438 ± 0.035	0.0GlyXaa: 0.0 ± 0.0
His	3.09HisAla: 3.09 ± 0.039	0.277HisCys: 0.277 ± 0.013	1.356HisAsp: 1.356 ± 0.029	1.242HisGlu: 1.242 ± 0.026	0.966HisPhe: 0.966 ± 0.019	2.2HisGly: 2.2 ± 0.04	0.616HisHis: 0.616 ± 0.017	0.927HisIle: 0.927 ± 0.022	0.536HisLys: 0.536 ± 0.017	2.145HisLeu: 2.145 ± 0.032	0.532HisMet: 0.532 ± 0.016	0.543HisAsn: 0.543 ± 0.016	1.415HisPro: 1.415 ± 0.026	0.639HisGln: 0.639 ± 0.017	1.54HisArg: 1.54 ± 0.028	1.133HisSer: 1.133 ± 0.026	1.173HisThr: 1.173 ± 0.022	1.756HisVal: 1.756 ± 0.03	0.407HisTrp: 0.407 ± 0.014	0.682HisTyr: 0.682 ± 0.018	0.0HisXaa: 0.0 ± 0.0
Ile	7.081IleAla: 7.081 ± 0.064	0.499IleCys: 0.499 ± 0.015	3.443IleAsp: 3.443 ± 0.039	3.285IleGlu: 3.285 ± 0.04	1.546IlePhe: 1.546 ± 0.03	4.977IleGly: 4.977 ± 0.05	0.93IleHis: 0.93 ± 0.022	1.659IleIle: 1.659 ± 0.027	1.314IleLys: 1.314 ± 0.025	3.453IleLeu: 3.453 ± 0.045	0.802IleMet: 0.802 ± 0.02	1.45IleAsn: 1.45 ± 0.029	2.144IlePro: 2.144 ± 0.035	1.277IleGln: 1.277 ± 0.026	2.908IleArg: 2.908 ± 0.04	2.628IleSer: 2.628 ± 0.041	2.446IleThr: 2.446 ± 0.039	4.457IleVal: 4.457 ± 0.049	0.523IleTrp: 0.523 ± 0.015	1.105IleTyr: 1.105 ± 0.025	0.0IleXaa: 0.0 ± 0.0
Lys	3.49LysAla: 3.49 ± 0.046	0.166LysCys: 0.166 ± 0.009	1.452LysAsp: 1.452 ± 0.032	1.394LysGlu: 1.394 ± 0.025	0.893LysPhe: 0.893 ± 0.021	2.066LysGly: 2.066 ± 0.035	0.669LysHis: 0.669 ± 0.021	1.52LysIle: 1.52 ± 0.03	1.172LysLys: 1.172 ± 0.033	3.328LysLeu: 3.328 ± 0.037	0.779LysMet: 0.779 ± 0.02	0.877LysAsn: 0.877 ± 0.023	1.933LysPro: 1.933 ± 0.028	1.271LysGln: 1.271 ± 0.025	2.338LysArg: 2.338 ± 0.032	1.665LysSer: 1.665 ± 0.03	1.813LysThr: 1.813 ± 0.032	2.277LysVal: 2.277 ± 0.034	0.367LysTrp: 0.367 ± 0.013	0.677LysTyr: 0.677 ± 0.018	0.0LysXaa: 0.0 ± 0.0
Leu	13.883LeuAla: 13.883 ± 0.098	1.053LeuCys: 1.053 ± 0.021	5.82LeuAsp: 5.82 ± 0.057	5.025LeuGlu: 5.025 ± 0.055	3.705LeuPhe: 3.705 ± 0.05	8.215LeuGly: 8.215 ± 0.075	2.261LeuHis: 2.261 ± 0.037	4.875LeuIle: 4.875 ± 0.055	3.262LeuLys: 3.262 ± 0.045	10.178LeuLeu: 10.178 ± 0.093	2.283LeuMet: 2.283 ± 0.035	2.881LeuAsn: 2.881 ± 0.04	5.777LeuPro: 5.777 ± 0.059	3.322LeuGln: 3.322 ± 0.035	7.08LeuArg: 7.08 ± 0.068	6.478LeuSer: 6.478 ± 0.059	5.592LeuThr: 5.592 ± 0.051	7.48LeuVal: 7.48 ± 0.065	1.156LeuTrp: 1.156 ± 0.022	2.184LeuTyr: 2.184 ± 0.033	0.0LeuXaa: 0.0 ± 0.0
Met	2.536MetAla: 2.536 ± 0.043	0.195MetCys: 0.195 ± 0.008	0.94MetAsp: 0.94 ± 0.02	0.901MetGlu: 0.901 ± 0.019	0.775MetPhe: 0.775 ± 0.02	1.561MetGly: 1.561 ± 0.028	0.531MetHis: 0.531 ± 0.015	1.141MetIle: 1.141 ± 0.022	1.061MetLys: 1.061 ± 0.022	2.761MetLeu: 2.761 ± 0.035	0.646MetMet: 0.646 ± 0.017	0.976MetAsn: 0.976 ± 0.02	1.509MetPro: 1.509 ± 0.026	0.998MetGln: 0.998 ± 0.02	1.809MetArg: 1.809 ± 0.029	1.845MetSer: 1.845 ± 0.027	1.705MetThr: 1.705 ± 0.03	1.574MetVal: 1.574 ± 0.038	0.231MetTrp: 0.231 ± 0.011	0.433MetTyr: 0.433 ± 0.013	0.0MetXaa: 0.0 ± 0.0
Asn	3.699AsnAla: 3.699 ± 0.055	0.271AsnCys: 0.271 ± 0.01	1.51AsnAsp: 1.51 ± 0.029	1.412AsnGlu: 1.412 ± 0.024	1.029AsnPhe: 1.029 ± 0.021	2.807AsnGly: 2.807 ± 0.048	0.566AsnHis: 0.566 ± 0.016	1.272AsnIle: 1.272 ± 0.028	0.653AsnLys: 0.653 ± 0.017	2.826AsnLeu: 2.826 ± 0.035	0.631AsnMet: 0.631 ± 0.016	0.897AsnAsn: 0.897 ± 0.028	1.854AsnPro: 1.854 ± 0.031	0.939AsnGln: 0.939 ± 0.024	1.862AsnArg: 1.862 ± 0.03	1.495AsnSer: 1.495 ± 0.031	1.572AsnThr: 1.572 ± 0.035	2.374AsnVal: 2.374 ± 0.045	0.433AsnTrp: 0.433 ± 0.013	0.783AsnTyr: 0.783 ± 0.019	0.0AsnXaa: 0.0 ± 0.0
Pro	6.574ProAla: 6.574 ± 0.069	0.342ProCys: 0.342 ± 0.012	3.133ProAsp: 3.133 ± 0.043	2.968ProGlu: 2.968 ± 0.036	1.986ProPhe: 1.986 ± 0.028	4.217ProGly: 4.217 ± 0.048	1.282ProHis: 1.282 ± 0.025	2.079ProIle: 2.079 ± 0.032	1.428ProLys: 1.428 ± 0.027	5.331ProLeu: 5.331 ± 0.055	1.12ProMet: 1.12 ± 0.022	1.477ProAsn: 1.477 ± 0.03	2.45ProPro: 2.45 ± 0.045	1.976ProGln: 1.976 ± 0.034	2.921ProArg: 2.921 ± 0.042	2.87ProSer: 2.87 ± 0.032	2.552ProThr: 2.552 ± 0.033	4.272ProVal: 4.272 ± 0.053	0.658ProTrp: 0.658 ± 0.02	1.24ProTyr: 1.24 ± 0.026	0.0ProXaa: 0.0 ± 0.0
Gln	4.351GlnAla: 4.351 ± 0.049	0.287GlnCys: 0.287 ± 0.012	1.356GlnAsp: 1.356 ± 0.023	1.35GlnGlu: 1.35 ± 0.028	1.349GlnPhe: 1.349 ± 0.025	2.498GlnGly: 2.498 ± 0.033	0.914GlnHis: 0.914 ± 0.021	2.035GlnIle: 2.035 ± 0.031	1.106GlnLys: 1.106 ± 0.02	3.834GlnLeu: 3.834 ± 0.053	1.072GlnMet: 1.072 ± 0.022	0.99GlnAsn: 0.99 ± 0.024	2.065GlnPro: 2.065 ± 0.034	1.945GlnGln: 1.945 ± 0.045	2.891GlnArg: 2.891 ± 0.042	2.127GlnSer: 2.127 ± 0.035	2.033GlnThr: 2.033 ± 0.03	2.407GlnVal: 2.407 ± 0.036	0.568GlnTrp: 0.568 ± 0.017	0.937GlnTyr: 0.937 ± 0.023	0.0GlnXaa: 0.0 ± 0.0
Arg	8.103ArgAla: 8.103 ± 0.083	0.606ArgCys: 0.606 ± 0.018	3.711ArgAsp: 3.711 ± 0.05	4.362ArgGlu: 4.362 ± 0.055	2.944ArgPhe: 2.944 ± 0.038	4.615ArgGly: 4.615 ± 0.048	1.904ArgHis: 1.904 ± 0.032	3.695ArgIle: 3.695 ± 0.036	2.132ArgLys: 2.132 ± 0.033	7.099ArgLeu: 7.099 ± 0.068	1.808ArgMet: 1.808 ± 0.03	1.991ArgAsn: 1.991 ± 0.027	2.998ArgPro: 2.998 ± 0.045	2.483ArgGln: 2.483 ± 0.037	5.243ArgArg: 5.243 ± 0.062	3.56ArgSer: 3.56 ± 0.036	3.418ArgThr: 3.418 ± 0.044	5.185ArgVal: 5.185 ± 0.05	1.018ArgTrp: 1.018 ± 0.023	1.938ArgTyr: 1.938 ± 0.032	0.0ArgXaa: 0.0 ± 0.0
Ser	7.197SerAla: 7.197 ± 0.071	0.48SerCys: 0.48 ± 0.015	2.847SerAsp: 2.847 ± 0.04	2.633SerGlu: 2.633 ± 0.035	2.291SerPhe: 2.291 ± 0.038	5.455SerGly: 5.455 ± 0.059	1.272SerHis: 1.272 ± 0.023	2.921SerIle: 2.921 ± 0.034	1.598SerLys: 1.598 ± 0.032	5.941SerLeu: 5.941 ± 0.059	1.449SerMet: 1.449 ± 0.026	1.764SerAsn: 1.764 ± 0.037	2.927SerPro: 2.927 ± 0.036	1.912SerGln: 1.912 ± 0.033	3.721SerArg: 3.721 ± 0.041	3.577SerSer: 3.577 ± 0.057	3.309SerThr: 3.309 ± 0.045	4.582SerVal: 4.582 ± 0.044	0.734SerTrp: 0.734 ± 0.021	1.345SerTyr: 1.345 ± 0.026	0.0SerXaa: 0.0 ± 0.0
Thr	6.073ThrAla: 6.073 ± 0.068	0.435ThrCys: 0.435 ± 0.014	2.607ThrAsp: 2.607 ± 0.042	2.295ThrGlu: 2.295 ± 0.034	2.025ThrPhe: 2.025 ± 0.033	4.875ThrGly: 4.875 ± 0.059	1.312ThrHis: 1.312 ± 0.023	2.66ThrIle: 2.66 ± 0.034	1.252ThrLys: 1.252 ± 0.024	6.59ThrLeu: 6.59 ± 0.052	1.203ThrMet: 1.203 ± 0.022	1.47ThrAsn: 1.47 ± 0.041	3.58ThrPro: 3.58 ± 0.043	2.055ThrGln: 2.055 ± 0.034	3.578ThrArg: 3.578 ± 0.043	3.092ThrSer: 3.092 ± 0.044	2.973ThrThr: 2.973 ± 0.044	4.329ThrVal: 4.329 ± 0.05	0.725ThrTrp: 0.725 ± 0.019	1.344ThrTyr: 1.344 ± 0.029	0.0ThrXaa: 0.0 ± 0.0
Val	9.463ValAla: 9.463 ± 0.065	0.829ValCys: 0.829 ± 0.02	4.207ValAsp: 4.207 ± 0.053	4.154ValGlu: 4.154 ± 0.051	2.923ValPhe: 2.923 ± 0.038	5.577ValGly: 5.577 ± 0.053	1.525ValHis: 1.525 ± 0.027	3.896ValIle: 3.896 ± 0.053	2.389ValLys: 2.389 ± 0.039	8.038ValLeu: 8.038 ± 0.074	1.932ValMet: 1.932 ± 0.036	2.276ValAsn: 2.276 ± 0.038	4.055ValPro: 4.055 ± 0.042	2.479ValGln: 2.479 ± 0.039	5.052ValArg: 5.052 ± 0.05	4.807ValSer: 4.807 ± 0.055	4.512ValThr: 4.512 ± 0.051	6.299ValVal: 6.299 ± 0.076	0.928ValTrp: 0.928 ± 0.02	1.751ValTyr: 1.751 ± 0.027	0.0ValXaa: 0.0 ± 0.0
Trp	1.144TrpAla: 1.144 ± 0.024	0.148TrpCys: 0.148 ± 0.009	0.605TrpAsp: 0.605 ± 0.018	0.514TrpGlu: 0.514 ± 0.014	0.573TrpPhe: 0.573 ± 0.017	0.897TrpGly: 0.897 ± 0.025	0.397TrpHis: 0.397 ± 0.015	0.723TrpIle: 0.723 ± 0.018	0.43TrpLys: 0.43 ± 0.014	1.939TrpLeu: 1.939 ± 0.035	0.362TrpMet: 0.362 ± 0.012	0.468TrpAsn: 0.468 ± 0.016	0.652TrpPro: 0.652 ± 0.019	0.661TrpGln: 0.661 ± 0.016	1.186TrpArg: 1.186 ± 0.024	0.82TrpSer: 0.82 ± 0.022	0.717TrpThr: 0.717 ± 0.022	0.899TrpVal: 0.899 ± 0.022	0.236TrpTrp: 0.236 ± 0.011	0.329TrpTyr: 0.329 ± 0.011	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.822TyrAla: 2.822 ± 0.041	0.3TyrCys: 0.3 ± 0.011	1.397TyrAsp: 1.397 ± 0.028	1.247TyrGlu: 1.247 ± 0.026	1.064TyrPhe: 1.064 ± 0.023	2.175TyrGly: 2.175 ± 0.031	0.538TyrHis: 0.538 ± 0.015	0.92TyrIle: 0.92 ± 0.022	0.619TyrLys: 0.619 ± 0.018	2.538TyrLeu: 2.538 ± 0.038	0.476TyrMet: 0.476 ± 0.017	0.639TyrAsn: 0.639 ± 0.019	1.299TyrPro: 1.299 ± 0.023	0.851TyrGln: 0.851 ± 0.021	1.903TyrArg: 1.903 ± 0.029	1.37TyrSer: 1.37 ± 0.027	1.327TyrThr: 1.327 ± 0.028	1.929TyrVal: 1.929 ± 0.032	0.388TyrTrp: 0.388 ± 0.013	0.676TyrTyr: 0.676 ± 0.018	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.007XaaXaa: 0.007 ± 0.007

Statistics based on 6846 proteins (2196354 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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