Amino acid dipepetide frequency for Chaetothyriales sp. CBS 132003

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	11.582AlaAla: 11.582 ± 0.085	0.997AlaCys: 0.997 ± 0.019	5.399AlaAsp: 5.399 ± 0.042	5.674AlaGlu: 5.674 ± 0.042	3.315AlaPhe: 3.315 ± 0.031	6.399AlaGly: 6.399 ± 0.053	2.161AlaHis: 2.161 ± 0.028	4.49AlaIle: 4.49 ± 0.039	4.834AlaLys: 4.834 ± 0.049	8.628AlaLeu: 8.628 ± 0.061	1.943AlaMet: 1.943 ± 0.025	3.276AlaAsn: 3.276 ± 0.035	5.06AlaPro: 5.06 ± 0.049	3.884AlaGln: 3.884 ± 0.039	5.799AlaArg: 5.799 ± 0.043	8.286AlaSer: 8.286 ± 0.057	5.777AlaThr: 5.777 ± 0.047	6.022AlaVal: 6.022 ± 0.045	1.186AlaTrp: 1.186 ± 0.017	2.326AlaTyr: 2.326 ± 0.027	0.0AlaXaa: 0.0 ± 0.0
Cys	0.874CysAla: 0.874 ± 0.017	0.176CysCys: 0.176 ± 0.008	0.56CysAsp: 0.56 ± 0.013	0.508CysGlu: 0.508 ± 0.013	0.488CysPhe: 0.488 ± 0.014	0.784CysGly: 0.784 ± 0.017	0.3CysHis: 0.3 ± 0.01	0.607CysIle: 0.607 ± 0.013	0.454CysLys: 0.454 ± 0.011	1.146CysLeu: 1.146 ± 0.019	0.222CysMet: 0.222 ± 0.009	0.365CysAsn: 0.365 ± 0.01	0.545CysPro: 0.545 ± 0.015	0.411CysGln: 0.411 ± 0.012	0.641CysArg: 0.641 ± 0.013	0.753CysSer: 0.753 ± 0.014	0.623CysThr: 0.623 ± 0.014	0.724CysVal: 0.724 ± 0.013	0.159CysTrp: 0.159 ± 0.006	0.313CysTyr: 0.313 ± 0.01	0.0CysXaa: 0.0 ± 0.0
Asp	5.561AspAla: 5.561 ± 0.05	0.562AspCys: 0.562 ± 0.011	4.74AspAsp: 4.74 ± 0.062	4.587AspGlu: 4.587 ± 0.049	2.304AspPhe: 2.304 ± 0.028	4.412AspGly: 4.412 ± 0.041	1.347AspHis: 1.347 ± 0.019	2.925AspIle: 2.925 ± 0.029	2.601AspLys: 2.601 ± 0.032	5.411AspLeu: 5.411 ± 0.046	1.242AspMet: 1.242 ± 0.022	1.849AspAsn: 1.849 ± 0.027	3.192AspPro: 3.192 ± 0.033	2.254AspGln: 2.254 ± 0.028	3.249AspArg: 3.249 ± 0.037	4.291AspSer: 4.291 ± 0.041	2.966AspThr: 2.966 ± 0.033	3.865AspVal: 3.865 ± 0.035	0.847AspTrp: 0.847 ± 0.016	1.588AspTyr: 1.588 ± 0.022	0.0AspXaa: 0.0 ± 0.0
Glu	5.986GluAla: 5.986 ± 0.052	0.559GluCys: 0.559 ± 0.015	3.734GluAsp: 3.734 ± 0.044	4.756GluGlu: 4.756 ± 0.058	1.776GluPhe: 1.776 ± 0.023	3.433GluGly: 3.433 ± 0.033	1.424GluHis: 1.424 ± 0.023	2.875GluIle: 2.875 ± 0.03	3.316GluLys: 3.316 ± 0.039	5.306GluLeu: 5.306 ± 0.051	1.367GluMet: 1.367 ± 0.021	1.842GluAsn: 1.842 ± 0.028	2.609GluPro: 2.609 ± 0.033	2.698GluGln: 2.698 ± 0.034	4.019GluArg: 4.019 ± 0.04	3.967GluSer: 3.967 ± 0.032	3.034GluThr: 3.034 ± 0.026	3.407GluVal: 3.407 ± 0.037	0.871GluTrp: 0.871 ± 0.017	1.618GluTyr: 1.618 ± 0.022	0.0GluXaa: 0.0 ± 0.0
Phe	3.141PheAla: 3.141 ± 0.032	0.5PheCys: 0.5 ± 0.013	2.389PheAsp: 2.389 ± 0.03	2.045PheGlu: 2.045 ± 0.026	1.526PhePhe: 1.526 ± 0.024	2.709PheGly: 2.709 ± 0.04	0.899PheHis: 0.899 ± 0.017	1.677PheIle: 1.677 ± 0.024	1.485PheLys: 1.485 ± 0.022	3.321PheLeu: 3.321 ± 0.035	0.678PheMet: 0.678 ± 0.016	1.375PheAsn: 1.375 ± 0.023	1.753PhePro: 1.753 ± 0.023	1.294PheGln: 1.294 ± 0.018	1.853PheArg: 1.853 ± 0.029	2.798PheSer: 2.798 ± 0.031	2.001PheThr: 2.001 ± 0.028	2.411PheVal: 2.411 ± 0.029	0.601PheTrp: 0.601 ± 0.014	1.063PheTyr: 1.063 ± 0.015	0.0PheXaa: 0.0 ± 0.0
Gly	5.54GlyAla: 5.54 ± 0.05	0.692GlyCys: 0.692 ± 0.016	3.729GlyAsp: 3.729 ± 0.03	3.502GlyGlu: 3.502 ± 0.037	2.629GlyPhe: 2.629 ± 0.034	5.608GlyGly: 5.608 ± 0.06	1.796GlyHis: 1.796 ± 0.022	3.305GlyIle: 3.305 ± 0.037	3.346GlyLys: 3.346 ± 0.036	6.134GlyLeu: 6.134 ± 0.048	1.425GlyMet: 1.425 ± 0.021	2.23GlyAsn: 2.23 ± 0.03	3.398GlyPro: 3.398 ± 0.039	2.88GlyGln: 2.88 ± 0.034	4.311GlyArg: 4.311 ± 0.037	5.534GlySer: 5.534 ± 0.07	3.775GlyThr: 3.775 ± 0.037	4.349GlyVal: 4.349 ± 0.043	1.09GlyTrp: 1.09 ± 0.021	1.96GlyTyr: 1.96 ± 0.029	0.0GlyXaa: 0.0 ± 0.0
His	2.229HisAla: 2.229 ± 0.028	0.285HisCys: 0.285 ± 0.009	1.532HisAsp: 1.532 ± 0.025	1.405HisGlu: 1.405 ± 0.023	0.928HisPhe: 0.928 ± 0.018	1.824HisGly: 1.824 ± 0.022	0.89HisHis: 0.89 ± 0.021	1.197HisIle: 1.197 ± 0.019	0.955HisLys: 0.955 ± 0.017	2.366HisLeu: 2.366 ± 0.027	0.451HisMet: 0.451 ± 0.012	0.823HisAsn: 0.823 ± 0.016	1.652HisPro: 1.652 ± 0.024	1.073HisGln: 1.073 ± 0.021	1.599HisArg: 1.599 ± 0.023	1.978HisSer: 1.978 ± 0.029	1.355HisThr: 1.355 ± 0.019	1.602HisVal: 1.602 ± 0.021	0.32HisTrp: 0.32 ± 0.011	0.705HisTyr: 0.705 ± 0.014	0.0HisXaa: 0.0 ± 0.0
Ile	4.303IleAla: 4.303 ± 0.042	0.642IleCys: 0.642 ± 0.012	3.061IleAsp: 3.061 ± 0.033	2.75IleGlu: 2.75 ± 0.034	1.833IlePhe: 1.833 ± 0.026	3.057IleGly: 3.057 ± 0.034	1.166IleHis: 1.166 ± 0.02	2.366IleIle: 2.366 ± 0.039	2.241IleLys: 2.241 ± 0.026	4.313IleLeu: 4.313 ± 0.044	0.902IleMet: 0.902 ± 0.015	1.832IleAsn: 1.832 ± 0.03	2.639IlePro: 2.639 ± 0.028	1.802IleGln: 1.802 ± 0.026	2.722IleArg: 2.722 ± 0.025	3.609IleSer: 3.609 ± 0.032	2.659IleThr: 2.659 ± 0.029	3.089IleVal: 3.089 ± 0.033	0.657IleTrp: 0.657 ± 0.016	1.307IleTyr: 1.307 ± 0.021	0.0IleXaa: 0.0 ± 0.0
Lys	4.92LysAla: 4.92 ± 0.049	0.43LysCys: 0.43 ± 0.013	2.772LysAsp: 2.772 ± 0.035	3.175LysGlu: 3.175 ± 0.042	1.431LysPhe: 1.431 ± 0.022	2.824LysGly: 2.824 ± 0.031	1.229LysHis: 1.229 ± 0.019	2.201LysIle: 2.201 ± 0.028	3.17LysLys: 3.17 ± 0.053	4.198LysLeu: 4.198 ± 0.045	0.984LysMet: 0.984 ± 0.021	1.549LysAsn: 1.549 ± 0.022	2.584LysPro: 2.584 ± 0.033	2.093LysGln: 2.093 ± 0.029	3.451LysArg: 3.451 ± 0.037	3.421LysSer: 3.421 ± 0.04	2.867LysThr: 2.867 ± 0.033	2.781LysVal: 2.781 ± 0.034	0.657LysTrp: 0.657 ± 0.013	1.396LysTyr: 1.396 ± 0.019	0.0LysXaa: 0.0 ± 0.0
Leu	8.939LeuAla: 8.939 ± 0.056	1.112LeuCys: 1.112 ± 0.019	5.686LeuAsp: 5.686 ± 0.049	5.194LeuGlu: 5.194 ± 0.05	3.196LeuPhe: 3.196 ± 0.039	5.897LeuGly: 5.897 ± 0.045	2.362LeuHis: 2.362 ± 0.028	3.986LeuIle: 3.986 ± 0.039	4.348LeuLys: 4.348 ± 0.046	8.723LeuLeu: 8.723 ± 0.066	1.653LeuMet: 1.653 ± 0.023	3.084LeuAsn: 3.084 ± 0.034	5.635LeuPro: 5.635 ± 0.044	3.946LeuGln: 3.946 ± 0.044	5.906LeuArg: 5.906 ± 0.042	7.451LeuSer: 7.451 ± 0.052	5.045LeuThr: 5.045 ± 0.045	5.744LeuVal: 5.744 ± 0.053	1.171LeuTrp: 1.171 ± 0.022	2.34LeuTyr: 2.34 ± 0.024	0.0LeuXaa: 0.0 ± 0.0
Met	2.316MetAla: 2.316 ± 0.025	0.218MetCys: 0.218 ± 0.009	1.151MetAsp: 1.151 ± 0.02	1.055MetGlu: 1.055 ± 0.019	0.625MetPhe: 0.625 ± 0.014	1.244MetGly: 1.244 ± 0.019	0.472MetHis: 0.472 ± 0.012	0.898MetIle: 0.898 ± 0.017	0.875MetLys: 0.875 ± 0.019	1.832MetLeu: 1.832 ± 0.023	0.496MetMet: 0.496 ± 0.014	0.669MetAsn: 0.669 ± 0.015	1.186MetPro: 1.186 ± 0.018	0.88MetGln: 0.88 ± 0.015	1.209MetArg: 1.209 ± 0.018	1.664MetSer: 1.664 ± 0.025	1.181MetThr: 1.181 ± 0.017	1.188MetVal: 1.188 ± 0.018	0.227MetTrp: 0.227 ± 0.009	0.483MetTyr: 0.483 ± 0.01	0.0MetXaa: 0.0 ± 0.0
Asn	3.218AsnAla: 3.218 ± 0.033	0.353AsnCys: 0.353 ± 0.01	1.964AsnAsp: 1.964 ± 0.029	1.866AsnGlu: 1.866 ± 0.027	1.254AsnPhe: 1.254 ± 0.019	2.799AsnGly: 2.799 ± 0.036	0.832AsnHis: 0.832 ± 0.017	1.826AsnIle: 1.826 ± 0.026	1.488AsnLys: 1.488 ± 0.021	3.076AsnLeu: 3.076 ± 0.028	0.71AsnMet: 0.71 ± 0.016	1.301AsnAsn: 1.301 ± 0.03	2.15AsnPro: 2.15 ± 0.029	1.28AsnGln: 1.28 ± 0.022	1.802AsnArg: 1.802 ± 0.022	2.484AsnSer: 2.484 ± 0.033	1.961AsnThr: 1.961 ± 0.029	2.248AsnVal: 2.248 ± 0.031	0.482AsnTrp: 0.482 ± 0.011	1.006AsnTyr: 1.006 ± 0.018	0.0AsnXaa: 0.0 ± 0.0
Pro	6.003ProAla: 6.003 ± 0.054	0.432ProCys: 0.432 ± 0.01	3.391ProAsp: 3.391 ± 0.032	3.262ProGlu: 3.262 ± 0.039	2.002ProPhe: 2.002 ± 0.029	3.863ProGly: 3.863 ± 0.041	1.431ProHis: 1.431 ± 0.024	2.326ProIle: 2.326 ± 0.029	2.455ProLys: 2.455 ± 0.035	4.894ProLeu: 4.894 ± 0.042	0.906ProMet: 0.906 ± 0.017	1.945ProAsn: 1.945 ± 0.025	5.168ProPro: 5.168 ± 0.076	2.378ProGln: 2.378 ± 0.036	3.464ProArg: 3.464 ± 0.04	5.893ProSer: 5.893 ± 0.052	3.83ProThr: 3.83 ± 0.034	3.535ProVal: 3.535 ± 0.038	0.665ProTrp: 0.665 ± 0.014	1.429ProTyr: 1.429 ± 0.022	0.0ProXaa: 0.0 ± 0.0
Gln	4.181GlnAla: 4.181 ± 0.042	0.39GlnCys: 0.39 ± 0.011	2.295GlnAsp: 2.295 ± 0.031	2.334GlnGlu: 2.334 ± 0.029	1.256GlnPhe: 1.256 ± 0.019	2.409GlnGly: 2.409 ± 0.03	1.289GlnHis: 1.289 ± 0.023	1.91GlnIle: 1.91 ± 0.025	2.048GlnLys: 2.048 ± 0.03	3.759GlnLeu: 3.759 ± 0.04	0.875GlnMet: 0.875 ± 0.019	1.398GlnAsn: 1.398 ± 0.022	2.727GlnPro: 2.727 ± 0.036	2.615GlnGln: 2.615 ± 0.039	2.884GlnArg: 2.884 ± 0.036	3.242GlnSer: 3.242 ± 0.036	2.295GlnThr: 2.295 ± 0.028	2.35GlnVal: 2.35 ± 0.026	0.56GlnTrp: 0.56 ± 0.014	1.18GlnTyr: 1.18 ± 0.023	0.0GlnXaa: 0.0 ± 0.0
Arg	5.439ArgAla: 5.439 ± 0.043	0.633ArgCys: 0.633 ± 0.015	3.558ArgAsp: 3.558 ± 0.039	3.839ArgGlu: 3.839 ± 0.038	2.045ArgPhe: 2.045 ± 0.026	3.732ArgGly: 3.732 ± 0.033	1.695ArgHis: 1.695 ± 0.023	2.856ArgIle: 2.856 ± 0.028	3.511ArgLys: 3.511 ± 0.036	5.905ArgLeu: 5.905 ± 0.049	1.241ArgMet: 1.241 ± 0.02	2.046ArgAsn: 2.046 ± 0.029	3.822ArgPro: 3.822 ± 0.044	3.01ArgGln: 3.01 ± 0.036	5.32ArgArg: 5.32 ± 0.054	4.781ArgSer: 4.781 ± 0.047	3.248ArgThr: 3.248 ± 0.031	3.49ArgVal: 3.49 ± 0.033	0.876ArgTrp: 0.876 ± 0.018	1.591ArgTyr: 1.591 ± 0.022	0.0ArgXaa: 0.0 ± 0.0
Ser	7.62SerAla: 7.62 ± 0.052	0.724SerCys: 0.724 ± 0.016	4.331SerAsp: 4.331 ± 0.037	3.811SerGlu: 3.811 ± 0.041	2.81SerPhe: 2.81 ± 0.026	5.423SerGly: 5.423 ± 0.068	2.009SerHis: 2.009 ± 0.028	3.821SerIle: 3.821 ± 0.034	3.641SerLys: 3.641 ± 0.035	7.432SerLeu: 7.432 ± 0.053	1.574SerMet: 1.574 ± 0.021	2.753SerAsn: 2.753 ± 0.032	5.505SerPro: 5.505 ± 0.059	3.265SerGln: 3.265 ± 0.036	5.086SerArg: 5.086 ± 0.049	8.517SerSer: 8.517 ± 0.077	5.402SerThr: 5.402 ± 0.051	4.642SerVal: 4.642 ± 0.041	1.003SerTrp: 1.003 ± 0.019	1.93SerTyr: 1.93 ± 0.026	0.0SerXaa: 0.0 ± 0.0
Thr	5.965ThrAla: 5.965 ± 0.046	0.624ThrCys: 0.624 ± 0.013	2.923ThrAsp: 2.923 ± 0.028	2.809ThrGlu: 2.809 ± 0.03	2.097ThrPhe: 2.097 ± 0.025	3.929ThrGly: 3.929 ± 0.039	1.3ThrHis: 1.3 ± 0.02	2.876ThrIle: 2.876 ± 0.03	2.562ThrLys: 2.562 ± 0.031	5.298ThrLeu: 5.298 ± 0.046	1.096ThrMet: 1.096 ± 0.017	1.992ThrAsn: 1.992 ± 0.027	4.132ThrPro: 4.132 ± 0.039	1.993ThrGln: 1.993 ± 0.026	3.146ThrArg: 3.146 ± 0.027	5.087ThrSer: 5.087 ± 0.051	4.064ThrThr: 4.064 ± 0.042	3.69ThrVal: 3.69 ± 0.035	0.771ThrTrp: 0.771 ± 0.015	1.475ThrTyr: 1.475 ± 0.022	0.0ThrXaa: 0.0 ± 0.0
Val	5.779ValAla: 5.779 ± 0.049	0.791ValCys: 0.791 ± 0.016	4.077ValAsp: 4.077 ± 0.033	3.79ValGlu: 3.79 ± 0.043	2.361ValPhe: 2.361 ± 0.031	4.056ValGly: 4.056 ± 0.039	1.478ValHis: 1.478 ± 0.019	2.819ValIle: 2.819 ± 0.035	3.008ValLys: 3.008 ± 0.032	5.683ValLeu: 5.683 ± 0.051	1.231ValMet: 1.231 ± 0.02	2.197ValAsn: 2.197 ± 0.03	3.551ValPro: 3.551 ± 0.035	2.554ValGln: 2.554 ± 0.025	3.649ValArg: 3.649 ± 0.032	4.639ValSer: 4.639 ± 0.039	3.327ValThr: 3.327 ± 0.037	4.524ValVal: 4.524 ± 0.05	0.851ValTrp: 0.851 ± 0.017	1.731ValTyr: 1.731 ± 0.025	0.0ValXaa: 0.0 ± 0.0
Trp	1.129TrpAla: 1.129 ± 0.018	0.174TrpCys: 0.174 ± 0.007	0.828TrpAsp: 0.828 ± 0.018	0.756TrpGlu: 0.756 ± 0.014	0.491TrpPhe: 0.491 ± 0.013	0.772TrpGly: 0.772 ± 0.017	0.359TrpHis: 0.359 ± 0.01	0.712TrpIle: 0.712 ± 0.015	0.751TrpLys: 0.751 ± 0.013	1.347TrpLeu: 1.347 ± 0.022	0.343TrpMet: 0.343 ± 0.011	0.548TrpAsn: 0.548 ± 0.014	0.6TrpPro: 0.6 ± 0.015	0.607TrpGln: 0.607 ± 0.013	0.939TrpArg: 0.939 ± 0.017	0.985TrpSer: 0.985 ± 0.019	0.875TrpThr: 0.875 ± 0.016	0.769TrpVal: 0.769 ± 0.014	0.267TrpTrp: 0.267 ± 0.008	0.398TrpTyr: 0.398 ± 0.013	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.313TyrAla: 2.313 ± 0.025	0.358TyrCys: 0.358 ± 0.011	1.676TyrAsp: 1.676 ± 0.023	1.481TyrGlu: 1.481 ± 0.023	1.149TyrPhe: 1.149 ± 0.019	2.062TyrGly: 2.062 ± 0.031	0.73TyrHis: 0.73 ± 0.017	1.276TyrIle: 1.276 ± 0.019	1.048TyrLys: 1.048 ± 0.019	2.645TyrLeu: 2.645 ± 0.028	0.529TyrMet: 0.529 ± 0.013	1.027TyrAsn: 1.027 ± 0.019	1.364TyrPro: 1.364 ± 0.026	1.081TyrGln: 1.081 ± 0.02	1.587TyrArg: 1.587 ± 0.023	1.915TyrSer: 1.915 ± 0.028	1.542TyrThr: 1.542 ± 0.021	1.666TyrVal: 1.666 ± 0.019	0.391TyrTrp: 0.391 ± 0.011	0.9TyrTyr: 0.9 ± 0.019	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 5726 proteins (3461870 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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