Amino acid dipepetide frequency for Siansivirga zeaxanthinifaciens CC-SAMT-1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.09AlaAla: 4.09 ± 0.086
0.627AlaCys: 0.627 ± 0.034
3.178AlaAsp: 3.178 ± 0.081
3.867AlaGlu: 3.867 ± 0.068
3.594AlaPhe: 3.594 ± 0.064
4.052AlaGly: 4.052 ± 0.079
1.146AlaHis: 1.146 ± 0.037
5.469AlaIle: 5.469 ± 0.087
4.624AlaLys: 4.624 ± 0.093
6.371AlaLeu: 6.371 ± 0.089
1.443AlaMet: 1.443 ± 0.046
3.734AlaAsn: 3.734 ± 0.064
1.99AlaPro: 1.99 ± 0.063
2.379AlaGln: 2.379 ± 0.052
1.895AlaArg: 1.895 ± 0.047
4.728AlaSer: 4.728 ± 0.112
3.803AlaThr: 3.803 ± 0.109
3.925AlaVal: 3.925 ± 0.078
0.608AlaTrp: 0.608 ± 0.026
2.568AlaTyr: 2.568 ± 0.052
0.0AlaXaa: 0.0 ± 0.0
Cys
0.45CysAla: 0.45 ± 0.028
0.078CysCys: 0.078 ± 0.009
0.456CysAsp: 0.456 ± 0.035
0.496CysGlu: 0.496 ± 0.029
0.445CysPhe: 0.445 ± 0.023
0.682CysGly: 0.682 ± 0.056
0.166CysHis: 0.166 ± 0.015
0.616CysIle: 0.616 ± 0.028
0.537CysLys: 0.537 ± 0.024
0.652CysLeu: 0.652 ± 0.027
0.145CysMet: 0.145 ± 0.012
0.437CysAsn: 0.437 ± 0.032
0.332CysPro: 0.332 ± 0.022
0.209CysGln: 0.209 ± 0.019
0.166CysArg: 0.166 ± 0.015
0.566CysSer: 0.566 ± 0.043
0.448CysThr: 0.448 ± 0.042
0.419CysVal: 0.419 ± 0.019
0.07CysTrp: 0.07 ± 0.009
0.333CysTyr: 0.333 ± 0.018
0.0CysXaa: 0.0 ± 0.0
Asp
4.217AspAla: 4.217 ± 0.088
0.449AspCys: 0.449 ± 0.032
3.049AspAsp: 3.049 ± 0.072
3.403AspGlu: 3.403 ± 0.078
3.625AspPhe: 3.625 ± 0.057
3.621AspGly: 3.621 ± 0.086
0.822AspHis: 0.822 ± 0.029
4.764AspIle: 4.764 ± 0.086
4.168AspLys: 4.168 ± 0.075
5.294AspLeu: 5.294 ± 0.076
1.078AspMet: 1.078 ± 0.034
3.403AspAsn: 3.403 ± 0.086
1.517AspPro: 1.517 ± 0.046
1.286AspGln: 1.286 ± 0.044
1.686AspArg: 1.686 ± 0.042
3.079AspSer: 3.079 ± 0.061
2.897AspThr: 2.897 ± 0.071
3.918AspVal: 3.918 ± 0.082
0.716AspTrp: 0.716 ± 0.029
2.832AspTyr: 2.832 ± 0.055
0.0AspXaa: 0.0 ± 0.0
Glu
4.838GluAla: 4.838 ± 0.087
0.323GluCys: 0.323 ± 0.034
3.547GluAsp: 3.547 ± 0.074
3.896GluGlu: 3.896 ± 0.094
2.935GluPhe: 2.935 ± 0.066
3.486GluGly: 3.486 ± 0.069
1.097GluHis: 1.097 ± 0.035
5.189GluIle: 5.189 ± 0.088
5.157GluLys: 5.157 ± 0.111
5.824GluLeu: 5.824 ± 0.097
1.308GluMet: 1.308 ± 0.05
4.664GluAsn: 4.664 ± 0.072
1.591GluPro: 1.591 ± 0.046
2.153GluGln: 2.153 ± 0.055
2.273GluArg: 2.273 ± 0.055
3.474GluSer: 3.474 ± 0.066
4.198GluThr: 4.198 ± 0.07
4.024GluVal: 4.024 ± 0.073
0.572GluTrp: 0.572 ± 0.027
2.197GluTyr: 2.197 ± 0.054
0.0GluXaa: 0.0 ± 0.0
Phe
2.881PheAla: 2.881 ± 0.056
0.431PheCys: 0.431 ± 0.021
3.279PheAsp: 3.279 ± 0.067
3.427PheGlu: 3.427 ± 0.057
2.677PhePhe: 2.677 ± 0.067
3.599PheGly: 3.599 ± 0.065
0.796PheHis: 0.796 ± 0.031
4.098PheIle: 4.098 ± 0.085
4.348PheLys: 4.348 ± 0.082
4.609PheLeu: 4.609 ± 0.092
1.054PheMet: 1.054 ± 0.041
3.954PheAsn: 3.954 ± 0.076
1.611PhePro: 1.611 ± 0.043
1.497PheGln: 1.497 ± 0.039
1.459PheArg: 1.459 ± 0.043
3.936PheSer: 3.936 ± 0.073
3.088PheThr: 3.088 ± 0.08
3.103PheVal: 3.103 ± 0.063
0.556PheTrp: 0.556 ± 0.025
2.167PheTyr: 2.167 ± 0.054
0.0PheXaa: 0.0 ± 0.0
Gly
4.215GlyAla: 4.215 ± 0.079
0.624GlyCys: 0.624 ± 0.052
3.511GlyAsp: 3.511 ± 0.084
3.433GlyGlu: 3.433 ± 0.065
3.714GlyPhe: 3.714 ± 0.07
4.421GlyGly: 4.421 ± 0.097
1.108GlyHis: 1.108 ± 0.037
5.4GlyIle: 5.4 ± 0.084
4.684GlyLys: 4.684 ± 0.089
5.747GlyLeu: 5.747 ± 0.088
1.447GlyMet: 1.447 ± 0.042
3.947GlyAsn: 3.947 ± 0.106
1.356GlyPro: 1.356 ± 0.033
1.775GlyGln: 1.775 ± 0.047
1.975GlyArg: 1.975 ± 0.051
3.939GlySer: 3.939 ± 0.082
3.906GlyThr: 3.906 ± 0.107
4.468GlyVal: 4.468 ± 0.084
0.801GlyTrp: 0.801 ± 0.035
2.754GlyTyr: 2.754 ± 0.053
0.0GlyXaa: 0.0 ± 0.0
His
1.083HisAla: 1.083 ± 0.035
0.169HisCys: 0.169 ± 0.014
0.869HisAsp: 0.869 ± 0.031
0.896HisGlu: 0.896 ± 0.032
1.125HisPhe: 1.125 ± 0.031
1.083HisGly: 1.083 ± 0.037
0.462HisHis: 0.462 ± 0.022
1.524HisIle: 1.524 ± 0.041
1.158HisLys: 1.158 ± 0.036
1.747HisLeu: 1.747 ± 0.047
0.303HisMet: 0.303 ± 0.02
0.984HisAsn: 0.984 ± 0.034
0.83HisPro: 0.83 ± 0.03
0.683HisGln: 0.683 ± 0.03
0.585HisArg: 0.585 ± 0.024
1.003HisSer: 1.003 ± 0.032
0.906HisThr: 0.906 ± 0.035
1.063HisVal: 1.063 ± 0.035
0.224HisTrp: 0.224 ± 0.019
0.803HisTyr: 0.803 ± 0.029
0.0HisXaa: 0.0 ± 0.0
Ile
5.421IleAla: 5.421 ± 0.086
0.657IleCys: 0.657 ± 0.029
5.017IleAsp: 5.017 ± 0.07
5.655IleGlu: 5.655 ± 0.089
3.543IlePhe: 3.543 ± 0.072
5.12IleGly: 5.12 ± 0.091
1.388IleHis: 1.388 ± 0.038
6.544IleIle: 6.544 ± 0.102
6.571IleLys: 6.571 ± 0.101
7.152IleLeu: 7.152 ± 0.108
1.419IleMet: 1.419 ± 0.043
5.417IleAsn: 5.417 ± 0.073
3.198IlePro: 3.198 ± 0.056
2.452IleGln: 2.452 ± 0.054
2.389IleArg: 2.389 ± 0.054
5.892IleSer: 5.892 ± 0.087
5.158IleThr: 5.158 ± 0.091
4.78IleVal: 4.78 ± 0.073
0.693IleTrp: 0.693 ± 0.03
2.853IleTyr: 2.853 ± 0.059
0.0IleXaa: 0.0 ± 0.0
Lys
5.275LysAla: 5.275 ± 0.103
0.325LysCys: 0.325 ± 0.019
4.623LysAsp: 4.623 ± 0.078
5.61LysGlu: 5.61 ± 0.111
3.024LysPhe: 3.024 ± 0.063
4.431LysGly: 4.431 ± 0.088
1.598LysHis: 1.598 ± 0.043
6.215LysIle: 6.215 ± 0.103
6.505LysLys: 6.505 ± 0.114
6.922LysLeu: 6.922 ± 0.121
1.891LysMet: 1.891 ± 0.05
5.677LysAsn: 5.677 ± 0.092
2.701LysPro: 2.701 ± 0.06
3.012LysGln: 3.012 ± 0.069
2.907LysArg: 2.907 ± 0.068
4.722LysSer: 4.722 ± 0.092
5.153LysThr: 5.153 ± 0.098
4.531LysVal: 4.531 ± 0.072
0.75LysTrp: 0.75 ± 0.03
3.04LysTyr: 3.04 ± 0.062
0.0LysXaa: 0.0 ± 0.0
Leu
5.62LeuAla: 5.62 ± 0.09
0.675LeuCys: 0.675 ± 0.03
5.003LeuAsp: 5.003 ± 0.072
6.194LeuGlu: 6.194 ± 0.091
4.868LeuPhe: 4.868 ± 0.083
5.756LeuGly: 5.756 ± 0.095
1.457LeuHis: 1.457 ± 0.041
7.238LeuIle: 7.238 ± 0.107
8.455LeuLys: 8.455 ± 0.13
8.323LeuLeu: 8.323 ± 0.132
1.905LeuMet: 1.905 ± 0.047
6.438LeuAsn: 6.438 ± 0.093
3.542LeuPro: 3.542 ± 0.07
3.041LeuGln: 3.041 ± 0.064
2.916LeuArg: 2.916 ± 0.068
6.429LeuSer: 6.429 ± 0.095
5.179LeuThr: 5.179 ± 0.118
5.351LeuVal: 5.351 ± 0.082
0.81LeuTrp: 0.81 ± 0.029
3.079LeuTyr: 3.079 ± 0.066
0.0LeuXaa: 0.0 ± 0.0
Met
1.512MetAla: 1.512 ± 0.049
0.14MetCys: 0.14 ± 0.012
1.024MetAsp: 1.024 ± 0.031
1.129MetGlu: 1.129 ± 0.043
0.934MetPhe: 0.934 ± 0.033
1.27MetGly: 1.27 ± 0.04
0.42MetHis: 0.42 ± 0.021
1.402MetIle: 1.402 ± 0.048
1.941MetLys: 1.941 ± 0.047
1.873MetLeu: 1.873 ± 0.051
0.523MetMet: 0.523 ± 0.028
1.204MetAsn: 1.204 ± 0.035
0.828MetPro: 0.828 ± 0.026
0.796MetGln: 0.796 ± 0.028
0.8MetArg: 0.8 ± 0.033
1.379MetSer: 1.379 ± 0.039
1.049MetThr: 1.049 ± 0.029
1.269MetVal: 1.269 ± 0.045
0.156MetTrp: 0.156 ± 0.014
0.739MetTyr: 0.739 ± 0.028
0.0MetXaa: 0.0 ± 0.0
Asn
4.134AsnAla: 4.134 ± 0.066
0.545AsnCys: 0.545 ± 0.037
3.599AsnAsp: 3.599 ± 0.061
4.075AsnGlu: 4.075 ± 0.064
3.288AsnPhe: 3.288 ± 0.067
4.276AsnGly: 4.276 ± 0.118
1.134AsnHis: 1.134 ± 0.038
5.539AsnIle: 5.539 ± 0.092
5.083AsnLys: 5.083 ± 0.093
6.032AsnLeu: 6.032 ± 0.094
1.352AsnMet: 1.352 ± 0.035
4.77AsnAsn: 4.77 ± 0.101
2.874AsnPro: 2.874 ± 0.063
2.415AsnGln: 2.415 ± 0.051
2.151AsnArg: 2.151 ± 0.052
4.023AsnSer: 4.023 ± 0.083
4.324AsnThr: 4.324 ± 0.102
3.729AsnVal: 3.729 ± 0.076
0.783AsnTrp: 0.783 ± 0.032
3.108AsnTyr: 3.108 ± 0.06
0.0AsnXaa: 0.0 ± 0.0
Pro
1.835ProAla: 1.835 ± 0.054
0.189ProCys: 0.189 ± 0.014
2.032ProAsp: 2.032 ± 0.052
2.725ProGlu: 2.725 ± 0.057
1.915ProPhe: 1.915 ± 0.049
1.903ProGly: 1.903 ± 0.045
0.617ProHis: 0.617 ± 0.028
2.717ProIle: 2.717 ± 0.056
2.517ProLys: 2.517 ± 0.057
2.992ProLeu: 2.992 ± 0.058
0.653ProMet: 0.653 ± 0.027
2.425ProAsn: 2.425 ± 0.053
0.824ProPro: 0.824 ± 0.043
1.13ProGln: 1.13 ± 0.033
0.875ProArg: 0.875 ± 0.031
2.188ProSer: 2.188 ± 0.057
2.143ProThr: 2.143 ± 0.08
2.319ProVal: 2.319 ± 0.064
0.346ProTrp: 0.346 ± 0.019
1.441ProTyr: 1.441 ± 0.041
0.0ProXaa: 0.0 ± 0.0
Gln
2.044GlnAla: 2.044 ± 0.044
0.186GlnCys: 0.186 ± 0.018
1.626GlnAsp: 1.626 ± 0.047
2.066GlnGlu: 2.066 ± 0.051
1.66GlnPhe: 1.66 ± 0.04
1.865GlnGly: 1.865 ± 0.045
0.56GlnHis: 0.56 ± 0.024
2.711GlnIle: 2.711 ± 0.046
2.569GlnLys: 2.569 ± 0.067
3.403GlnLeu: 3.403 ± 0.066
0.757GlnMet: 0.757 ± 0.027
2.211GlnAsn: 2.211 ± 0.046
1.155GlnPro: 1.155 ± 0.035
1.249GlnGln: 1.249 ± 0.046
1.065GlnArg: 1.065 ± 0.034
1.85GlnSer: 1.85 ± 0.056
2.004GlnThr: 2.004 ± 0.048
2.042GlnVal: 2.042 ± 0.047
0.351GlnTrp: 0.351 ± 0.019
1.314GlnTyr: 1.314 ± 0.039
0.0GlnXaa: 0.0 ± 0.0
Arg
1.991ArgAla: 1.991 ± 0.055
0.203ArgCys: 0.203 ± 0.014
1.761ArgAsp: 1.761 ± 0.047
1.922ArgGlu: 1.922 ± 0.049
1.712ArgPhe: 1.712 ± 0.041
1.932ArgGly: 1.932 ± 0.049
0.582ArgHis: 0.582 ± 0.025
2.714ArgIle: 2.714 ± 0.058
2.41ArgLys: 2.41 ± 0.062
3.091ArgLeu: 3.091 ± 0.062
0.756ArgMet: 0.756 ± 0.034
1.967ArgAsn: 1.967 ± 0.046
1.067ArgPro: 1.067 ± 0.035
1.043ArgGln: 1.043 ± 0.033
1.203ArgArg: 1.203 ± 0.05
1.671ArgSer: 1.671 ± 0.049
1.761ArgThr: 1.761 ± 0.044
2.009ArgVal: 2.009 ± 0.046
0.386ArgTrp: 0.386 ± 0.022
1.415ArgTyr: 1.415 ± 0.038
0.0ArgXaa: 0.0 ± 0.0
Ser
3.736SerAla: 3.736 ± 0.072
0.659SerCys: 0.659 ± 0.037
3.489SerAsp: 3.489 ± 0.091
3.972SerGlu: 3.972 ± 0.073
3.705SerPhe: 3.705 ± 0.081
4.608SerGly: 4.608 ± 0.115
1.135SerHis: 1.135 ± 0.039
5.317SerIle: 5.317 ± 0.081
5.241SerLys: 5.241 ± 0.088
5.768SerLeu: 5.768 ± 0.089
1.217SerMet: 1.217 ± 0.035
4.513SerAsn: 4.513 ± 0.093
2.024SerPro: 2.024 ± 0.052
2.218SerGln: 2.218 ± 0.059
1.971SerArg: 1.971 ± 0.051
4.057SerSer: 4.057 ± 0.107
3.621SerThr: 3.621 ± 0.068
4.052SerVal: 4.052 ± 0.078
0.677SerTrp: 0.677 ± 0.03
2.637SerTyr: 2.637 ± 0.059
0.0SerXaa: 0.0 ± 0.0
Thr
3.751ThrAla: 3.751 ± 0.096
0.434ThrCys: 0.434 ± 0.041
3.312ThrAsp: 3.312 ± 0.075
3.371ThrGlu: 3.371 ± 0.058
3.205ThrPhe: 3.205 ± 0.063
4.159ThrGly: 4.159 ± 0.107
1.031ThrHis: 1.031 ± 0.035
5.243ThrIle: 5.243 ± 0.11
4.204ThrLys: 4.204 ± 0.073
5.744ThrLeu: 5.744 ± 0.102
0.957ThrMet: 0.957 ± 0.035
3.902ThrAsn: 3.902 ± 0.107
2.546ThrPro: 2.546 ± 0.077
1.888ThrGln: 1.888 ± 0.053
1.573ThrArg: 1.573 ± 0.039
3.989ThrSer: 3.989 ± 0.088
3.798ThrThr: 3.798 ± 0.109
3.997ThrVal: 3.997 ± 0.183
0.663ThrTrp: 0.663 ± 0.036
2.564ThrTyr: 2.564 ± 0.081
0.0ThrXaa: 0.0 ± 0.0
Val
3.997ValAla: 3.997 ± 0.093
0.583ValCys: 0.583 ± 0.033
3.54ValAsp: 3.54 ± 0.087
3.778ValGlu: 3.778 ± 0.063
3.542ValPhe: 3.542 ± 0.065
3.806ValGly: 3.806 ± 0.067
0.921ValHis: 0.921 ± 0.032
5.042ValIle: 5.042 ± 0.075
4.59ValLys: 4.59 ± 0.078
6.016ValLeu: 6.016 ± 0.082
1.198ValMet: 1.198 ± 0.041
3.849ValAsn: 3.849 ± 0.069
2.068ValPro: 2.068 ± 0.058
1.556ValGln: 1.556 ± 0.045
1.864ValArg: 1.864 ± 0.045
4.469ValSer: 4.469 ± 0.082
3.916ValThr: 3.916 ± 0.167
4.314ValVal: 4.314 ± 0.091
0.651ValTrp: 0.651 ± 0.029
2.432ValTyr: 2.432 ± 0.05
0.0ValXaa: 0.0 ± 0.0
Trp
0.549TrpAla: 0.549 ± 0.027
0.102TrpCys: 0.102 ± 0.011
0.647TrpAsp: 0.647 ± 0.034
0.647TrpGlu: 0.647 ± 0.028
0.624TrpPhe: 0.624 ± 0.025
0.647TrpGly: 0.647 ± 0.03
0.248TrpHis: 0.248 ± 0.018
0.721TrpIle: 0.721 ± 0.029
0.817TrpLys: 0.817 ± 0.037
0.938TrpLeu: 0.938 ± 0.04
0.28TrpMet: 0.28 ± 0.018
0.713TrpAsn: 0.713 ± 0.031
0.241TrpPro: 0.241 ± 0.018
0.415TrpGln: 0.415 ± 0.02
0.376TrpArg: 0.376 ± 0.019
0.655TrpSer: 0.655 ± 0.025
0.619TrpThr: 0.619 ± 0.04
0.628TrpVal: 0.628 ± 0.03
0.153TrpTrp: 0.153 ± 0.011
0.458TrpTyr: 0.458 ± 0.025
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.451TyrAla: 2.451 ± 0.054
0.304TyrCys: 0.304 ± 0.018
2.264TyrAsp: 2.264 ± 0.051
2.185TyrGlu: 2.185 ± 0.051
2.432TyrPhe: 2.432 ± 0.059
2.51TyrGly: 2.51 ± 0.061
0.811TyrHis: 0.811 ± 0.03
2.855TyrIle: 2.855 ± 0.064
3.335TyrLys: 3.335 ± 0.065
3.784TyrLeu: 3.784 ± 0.06
0.7TyrMet: 0.7 ± 0.028
3.024TyrAsn: 3.024 ± 0.071
1.489TyrPro: 1.489 ± 0.041
1.491TyrGln: 1.491 ± 0.042
1.471TyrArg: 1.471 ± 0.048
2.568TyrSer: 2.568 ± 0.059
2.358TyrThr: 2.358 ± 0.085
2.19TyrVal: 2.19 ± 0.047
0.511TyrTrp: 0.511 ± 0.026
1.852TyrTyr: 1.852 ± 0.053
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2744 proteins (966228 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski