Amino acid dipepetide frequency for Salmonella phage 103203_sal5

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
8.791AlaAla: 8.791 ± 1.426
1.232AlaCys: 1.232 ± 0.338
6.327AlaAsp: 6.327 ± 0.854
6.244AlaGlu: 6.244 ± 0.717
3.369AlaPhe: 3.369 ± 0.504
6.655AlaGly: 6.655 ± 0.828
1.232AlaHis: 1.232 ± 0.317
5.834AlaIle: 5.834 ± 0.735
5.258AlaLys: 5.258 ± 0.725
6.08AlaLeu: 6.08 ± 0.879
3.287AlaMet: 3.287 ± 0.629
6.409AlaAsn: 6.409 ± 0.962
2.301AlaPro: 2.301 ± 0.384
3.369AlaGln: 3.369 ± 0.583
5.258AlaArg: 5.258 ± 0.673
4.93AlaSer: 4.93 ± 0.651
4.519AlaThr: 4.519 ± 0.812
5.505AlaVal: 5.505 ± 0.694
1.397AlaTrp: 1.397 ± 0.386
2.218AlaTyr: 2.218 ± 0.386
0.0AlaXaa: 0.0 ± 0.0
Cys
0.739CysAla: 0.739 ± 0.278
0.246CysCys: 0.246 ± 0.159
0.329CysAsp: 0.329 ± 0.155
0.575CysGlu: 0.575 ± 0.245
0.493CysPhe: 0.493 ± 0.167
1.232CysGly: 1.232 ± 0.32
0.411CysHis: 0.411 ± 0.166
0.822CysIle: 0.822 ± 0.354
0.411CysLys: 0.411 ± 0.202
0.411CysLeu: 0.411 ± 0.227
0.164CysMet: 0.164 ± 0.111
0.493CysAsn: 0.493 ± 0.187
0.164CysPro: 0.164 ± 0.124
0.411CysGln: 0.411 ± 0.174
1.15CysArg: 1.15 ± 0.29
0.411CysSer: 0.411 ± 0.178
0.411CysThr: 0.411 ± 0.191
1.15CysVal: 1.15 ± 0.284
0.164CysTrp: 0.164 ± 0.113
0.411CysTyr: 0.411 ± 0.164
0.0CysXaa: 0.0 ± 0.0
Asp
6.491AspAla: 6.491 ± 0.834
0.411AspCys: 0.411 ± 0.21
3.697AspAsp: 3.697 ± 0.573
4.108AspGlu: 4.108 ± 0.722
2.054AspPhe: 2.054 ± 0.367
5.094AspGly: 5.094 ± 0.926
0.904AspHis: 0.904 ± 0.326
4.519AspIle: 4.519 ± 0.476
3.204AspLys: 3.204 ± 0.467
5.176AspLeu: 5.176 ± 0.66
1.725AspMet: 1.725 ± 0.368
2.383AspAsn: 2.383 ± 0.472
1.643AspPro: 1.643 ± 0.372
1.397AspGln: 1.397 ± 0.306
1.972AspArg: 1.972 ± 0.398
3.369AspSer: 3.369 ± 0.531
1.972AspThr: 1.972 ± 0.399
4.19AspVal: 4.19 ± 0.657
1.068AspTrp: 1.068 ± 0.32
2.876AspTyr: 2.876 ± 0.457
0.0AspXaa: 0.0 ± 0.0
Glu
5.423GluAla: 5.423 ± 0.613
1.315GluCys: 1.315 ± 0.284
2.711GluAsp: 2.711 ± 0.462
4.108GluGlu: 4.108 ± 0.891
2.218GluPhe: 2.218 ± 0.49
3.287GluGly: 3.287 ± 0.422
1.315GluHis: 1.315 ± 0.31
3.862GluIle: 3.862 ± 0.536
3.944GluLys: 3.944 ± 0.542
5.998GluLeu: 5.998 ± 0.648
2.054GluMet: 2.054 ± 0.456
2.958GluAsn: 2.958 ± 0.531
2.794GluPro: 2.794 ± 0.431
4.026GluGln: 4.026 ± 0.595
4.108GluArg: 4.108 ± 0.718
3.04GluSer: 3.04 ± 0.373
2.711GluThr: 2.711 ± 0.465
3.369GluVal: 3.369 ± 0.523
1.808GluTrp: 1.808 ± 0.374
2.383GluTyr: 2.383 ± 0.386
0.0GluXaa: 0.0 ± 0.0
Phe
3.122PheAla: 3.122 ± 0.49
0.657PheCys: 0.657 ± 0.249
2.301PheAsp: 2.301 ± 0.467
1.972PheGlu: 1.972 ± 0.386
1.479PhePhe: 1.479 ± 0.451
2.629PheGly: 2.629 ± 0.461
0.246PheHis: 0.246 ± 0.148
2.794PheIle: 2.794 ± 0.801
2.136PheLys: 2.136 ± 0.409
1.972PheLeu: 1.972 ± 0.42
1.479PheMet: 1.479 ± 0.295
2.301PheAsn: 2.301 ± 0.472
1.561PhePro: 1.561 ± 0.312
1.15PheGln: 1.15 ± 0.348
1.643PheArg: 1.643 ± 0.334
3.287PheSer: 3.287 ± 0.64
2.547PheThr: 2.547 ± 0.47
1.725PheVal: 1.725 ± 0.323
0.739PheTrp: 0.739 ± 0.256
1.397PheTyr: 1.397 ± 0.368
0.0PheXaa: 0.0 ± 0.0
Gly
5.505GlyAla: 5.505 ± 0.929
0.575GlyCys: 0.575 ± 0.189
4.272GlyAsp: 4.272 ± 0.652
3.944GlyGlu: 3.944 ± 0.482
2.711GlyPhe: 2.711 ± 0.488
5.669GlyGly: 5.669 ± 1.03
0.904GlyHis: 0.904 ± 0.312
4.601GlyIle: 4.601 ± 0.605
5.012GlyLys: 5.012 ± 0.714
5.176GlyLeu: 5.176 ± 0.715
2.629GlyMet: 2.629 ± 0.561
3.04GlyAsn: 3.04 ± 0.521
0.904GlyPro: 0.904 ± 0.245
3.615GlyGln: 3.615 ± 0.762
5.423GlyArg: 5.423 ± 0.705
4.272GlySer: 4.272 ± 0.875
3.779GlyThr: 3.779 ± 0.543
5.834GlyVal: 5.834 ± 0.677
1.972GlyTrp: 1.972 ± 0.376
1.89GlyTyr: 1.89 ± 0.351
0.0GlyXaa: 0.0 ± 0.0
His
0.986HisAla: 0.986 ± 0.278
0.164HisCys: 0.164 ± 0.114
0.904HisAsp: 0.904 ± 0.314
1.068HisGlu: 1.068 ± 0.297
0.575HisPhe: 0.575 ± 0.198
1.15HisGly: 1.15 ± 0.327
0.246HisHis: 0.246 ± 0.136
0.739HisIle: 0.739 ± 0.229
0.739HisLys: 0.739 ± 0.245
1.89HisLeu: 1.89 ± 0.433
0.493HisMet: 0.493 ± 0.195
0.493HisAsn: 0.493 ± 0.203
1.15HisPro: 1.15 ± 0.272
0.904HisGln: 0.904 ± 0.258
1.397HisArg: 1.397 ± 0.387
0.904HisSer: 0.904 ± 0.218
0.575HisThr: 0.575 ± 0.206
1.15HisVal: 1.15 ± 0.302
0.329HisTrp: 0.329 ± 0.155
0.493HisTyr: 0.493 ± 0.216
0.0HisXaa: 0.0 ± 0.0
Ile
6.244IleAla: 6.244 ± 0.7
0.493IleCys: 0.493 ± 0.156
3.615IleAsp: 3.615 ± 0.472
4.355IleGlu: 4.355 ± 0.656
2.218IlePhe: 2.218 ± 0.629
5.012IleGly: 5.012 ± 0.706
1.397IleHis: 1.397 ± 0.307
4.19IleIle: 4.19 ± 1.01
3.369IleLys: 3.369 ± 0.555
4.437IleLeu: 4.437 ± 0.831
1.397IleMet: 1.397 ± 0.376
2.876IleAsn: 2.876 ± 0.654
3.204IlePro: 3.204 ± 0.604
2.383IleGln: 2.383 ± 0.456
3.533IleArg: 3.533 ± 0.456
5.012IleSer: 5.012 ± 0.914
4.437IleThr: 4.437 ± 0.698
3.04IleVal: 3.04 ± 0.557
0.657IleTrp: 0.657 ± 0.209
2.301IleTyr: 2.301 ± 0.492
0.0IleXaa: 0.0 ± 0.0
Lys
4.848LysAla: 4.848 ± 0.668
0.493LysCys: 0.493 ± 0.232
3.533LysAsp: 3.533 ± 0.514
3.779LysGlu: 3.779 ± 0.637
2.136LysPhe: 2.136 ± 0.405
4.108LysGly: 4.108 ± 0.623
0.904LysHis: 0.904 ± 0.291
3.122LysIle: 3.122 ± 0.518
4.683LysLys: 4.683 ± 0.664
5.012LysLeu: 5.012 ± 0.612
2.054LysMet: 2.054 ± 0.442
2.465LysAsn: 2.465 ± 0.428
3.944LysPro: 3.944 ± 0.632
3.287LysGln: 3.287 ± 0.541
4.848LysArg: 4.848 ± 0.878
3.615LysSer: 3.615 ± 0.528
3.369LysThr: 3.369 ± 0.558
2.876LysVal: 2.876 ± 0.487
0.575LysTrp: 0.575 ± 0.187
2.218LysTyr: 2.218 ± 0.459
0.0LysXaa: 0.0 ± 0.0
Leu
7.312LeuAla: 7.312 ± 0.757
0.822LeuCys: 0.822 ± 0.255
3.779LeuAsp: 3.779 ± 0.602
4.765LeuGlu: 4.765 ± 0.541
2.958LeuPhe: 2.958 ± 0.543
4.601LeuGly: 4.601 ± 0.801
1.15LeuHis: 1.15 ± 0.303
5.916LeuIle: 5.916 ± 1.009
5.587LeuLys: 5.587 ± 0.664
6.573LeuLeu: 6.573 ± 0.827
2.794LeuMet: 2.794 ± 0.421
4.272LeuAsn: 4.272 ± 0.651
3.122LeuPro: 3.122 ± 0.515
2.711LeuGln: 2.711 ± 0.468
3.944LeuArg: 3.944 ± 0.605
5.916LeuSer: 5.916 ± 0.745
5.012LeuThr: 5.012 ± 0.511
4.683LeuVal: 4.683 ± 0.562
1.15LeuTrp: 1.15 ± 0.316
2.629LeuTyr: 2.629 ± 0.465
0.0LeuXaa: 0.0 ± 0.0
Met
2.958MetAla: 2.958 ± 0.615
0.411MetCys: 0.411 ± 0.243
1.397MetAsp: 1.397 ± 0.335
1.315MetGlu: 1.315 ± 0.279
0.575MetPhe: 0.575 ± 0.283
1.643MetGly: 1.643 ± 0.381
0.164MetHis: 0.164 ± 0.118
1.808MetIle: 1.808 ± 0.388
3.122MetLys: 3.122 ± 0.563
2.301MetLeu: 2.301 ± 0.307
0.986MetMet: 0.986 ± 0.313
1.397MetAsn: 1.397 ± 0.329
0.986MetPro: 0.986 ± 0.259
1.725MetGln: 1.725 ± 0.431
2.629MetArg: 2.629 ± 0.559
2.383MetSer: 2.383 ± 0.515
1.972MetThr: 1.972 ± 0.434
1.643MetVal: 1.643 ± 0.349
0.164MetTrp: 0.164 ± 0.115
1.15MetTyr: 1.15 ± 0.277
0.0MetXaa: 0.0 ± 0.0
Asn
4.93AsnAla: 4.93 ± 0.777
0.082AsnCys: 0.082 ± 0.096
2.629AsnAsp: 2.629 ± 0.448
2.958AsnGlu: 2.958 ± 0.411
1.397AsnPhe: 1.397 ± 0.351
4.848AsnGly: 4.848 ± 0.561
0.986AsnHis: 0.986 ± 0.294
2.876AsnIle: 2.876 ± 0.515
2.958AsnLys: 2.958 ± 0.544
2.958AsnLeu: 2.958 ± 0.516
1.479AsnMet: 1.479 ± 0.333
2.629AsnAsn: 2.629 ± 0.526
3.204AsnPro: 3.204 ± 0.467
1.972AsnGln: 1.972 ± 0.507
2.301AsnArg: 2.301 ± 0.417
2.547AsnSer: 2.547 ± 0.459
2.958AsnThr: 2.958 ± 0.576
2.876AsnVal: 2.876 ± 0.678
0.411AsnTrp: 0.411 ± 0.175
1.315AsnTyr: 1.315 ± 0.351
0.0AsnXaa: 0.0 ± 0.0
Pro
2.629ProAla: 2.629 ± 0.414
0.082ProCys: 0.082 ± 0.08
3.204ProAsp: 3.204 ± 0.507
4.765ProGlu: 4.765 ± 0.655
1.725ProPhe: 1.725 ± 0.359
2.218ProGly: 2.218 ± 0.423
0.657ProHis: 0.657 ± 0.225
2.383ProIle: 2.383 ± 0.388
2.465ProLys: 2.465 ± 0.444
3.287ProLeu: 3.287 ± 0.579
1.232ProMet: 1.232 ± 0.336
1.479ProAsn: 1.479 ± 0.371
1.808ProPro: 1.808 ± 0.416
1.89ProGln: 1.89 ± 0.335
1.808ProArg: 1.808 ± 0.388
3.04ProSer: 3.04 ± 0.411
1.725ProThr: 1.725 ± 0.259
3.204ProVal: 3.204 ± 0.543
0.411ProTrp: 0.411 ± 0.179
0.822ProTyr: 0.822 ± 0.286
0.0ProXaa: 0.0 ± 0.0
Gln
4.026GlnAla: 4.026 ± 0.582
0.411GlnCys: 0.411 ± 0.193
3.04GlnAsp: 3.04 ± 0.449
2.465GlnGlu: 2.465 ± 0.429
1.561GlnPhe: 1.561 ± 0.487
3.122GlnGly: 3.122 ± 0.613
0.904GlnHis: 0.904 ± 0.272
3.04GlnIle: 3.04 ± 0.425
1.725GlnLys: 1.725 ± 0.378
4.026GlnLeu: 4.026 ± 0.528
1.315GlnMet: 1.315 ± 0.27
2.054GlnAsn: 2.054 ± 0.665
1.808GlnPro: 1.808 ± 0.353
3.615GlnGln: 3.615 ± 0.908
2.629GlnArg: 2.629 ± 0.442
2.794GlnSer: 2.794 ± 0.503
1.561GlnThr: 1.561 ± 0.389
2.465GlnVal: 2.465 ± 0.493
0.822GlnTrp: 0.822 ± 0.233
1.89GlnTyr: 1.89 ± 0.46
0.0GlnXaa: 0.0 ± 0.0
Arg
4.93ArgAla: 4.93 ± 0.645
0.493ArgCys: 0.493 ± 0.192
3.944ArgAsp: 3.944 ± 0.539
4.026ArgGlu: 4.026 ± 0.549
2.218ArgPhe: 2.218 ± 0.502
3.287ArgGly: 3.287 ± 0.42
1.561ArgHis: 1.561 ± 0.323
4.601ArgIle: 4.601 ± 0.683
4.108ArgLys: 4.108 ± 0.762
4.848ArgLeu: 4.848 ± 0.533
2.136ArgMet: 2.136 ± 0.393
2.958ArgAsn: 2.958 ± 0.483
2.383ArgPro: 2.383 ± 0.407
2.301ArgGln: 2.301 ± 0.484
3.862ArgArg: 3.862 ± 0.773
3.451ArgSer: 3.451 ± 0.419
1.972ArgThr: 1.972 ± 0.397
3.204ArgVal: 3.204 ± 0.445
0.575ArgTrp: 0.575 ± 0.232
2.054ArgTyr: 2.054 ± 0.489
0.0ArgXaa: 0.0 ± 0.0
Ser
5.834SerAla: 5.834 ± 0.926
0.822SerCys: 0.822 ± 0.374
3.451SerAsp: 3.451 ± 0.425
3.615SerGlu: 3.615 ± 0.566
2.876SerPhe: 2.876 ± 0.523
5.341SerGly: 5.341 ± 0.902
1.15SerHis: 1.15 ± 0.322
3.779SerIle: 3.779 ± 0.597
3.697SerLys: 3.697 ± 0.46
5.423SerLeu: 5.423 ± 0.797
1.643SerMet: 1.643 ± 0.304
2.301SerAsn: 2.301 ± 0.358
2.876SerPro: 2.876 ± 0.475
3.122SerGln: 3.122 ± 0.468
3.369SerArg: 3.369 ± 0.467
3.451SerSer: 3.451 ± 0.706
2.876SerThr: 2.876 ± 0.59
3.779SerVal: 3.779 ± 0.635
0.904SerTrp: 0.904 ± 0.281
2.054SerTyr: 2.054 ± 0.458
0.0SerXaa: 0.0 ± 0.0
Thr
5.669ThrAla: 5.669 ± 0.754
0.493ThrCys: 0.493 ± 0.198
2.547ThrAsp: 2.547 ± 0.597
2.794ThrGlu: 2.794 ± 0.532
1.808ThrPhe: 1.808 ± 0.486
4.683ThrGly: 4.683 ± 0.561
0.904ThrHis: 0.904 ± 0.211
2.794ThrIle: 2.794 ± 0.516
3.04ThrLys: 3.04 ± 0.474
4.026ThrLeu: 4.026 ± 0.611
0.986ThrMet: 0.986 ± 0.264
2.301ThrAsn: 2.301 ± 0.491
3.04ThrPro: 3.04 ± 0.448
2.301ThrGln: 2.301 ± 0.419
2.136ThrArg: 2.136 ± 0.407
3.533ThrSer: 3.533 ± 0.643
2.794ThrThr: 2.794 ± 0.599
2.711ThrVal: 2.711 ± 0.491
0.575ThrTrp: 0.575 ± 0.236
1.068ThrTyr: 1.068 ± 0.258
0.0ThrXaa: 0.0 ± 0.0
Val
5.669ValAla: 5.669 ± 0.634
0.739ValCys: 0.739 ± 0.223
3.533ValAsp: 3.533 ± 0.506
4.272ValGlu: 4.272 ± 0.592
2.876ValPhe: 2.876 ± 0.514
3.944ValGly: 3.944 ± 0.626
0.411ValHis: 0.411 ± 0.145
3.779ValIle: 3.779 ± 0.598
3.944ValLys: 3.944 ± 0.499
5.669ValLeu: 5.669 ± 0.741
1.232ValMet: 1.232 ± 0.347
3.615ValAsn: 3.615 ± 0.564
1.725ValPro: 1.725 ± 0.389
2.054ValGln: 2.054 ± 0.352
3.122ValArg: 3.122 ± 0.426
3.779ValSer: 3.779 ± 0.706
3.369ValThr: 3.369 ± 0.632
5.012ValVal: 5.012 ± 0.471
0.822ValTrp: 0.822 ± 0.301
2.136ValTyr: 2.136 ± 0.483
0.0ValXaa: 0.0 ± 0.0
Trp
0.986TrpAla: 0.986 ± 0.27
0.164TrpCys: 0.164 ± 0.112
0.739TrpAsp: 0.739 ± 0.232
0.493TrpGlu: 0.493 ± 0.243
0.246TrpPhe: 0.246 ± 0.137
0.986TrpGly: 0.986 ± 0.272
0.411TrpHis: 0.411 ± 0.167
0.575TrpIle: 0.575 ± 0.218
1.068TrpLys: 1.068 ± 0.337
1.972TrpLeu: 1.972 ± 0.467
0.822TrpMet: 0.822 ± 0.246
0.329TrpAsn: 0.329 ± 0.16
0.739TrpPro: 0.739 ± 0.253
1.068TrpGln: 1.068 ± 0.238
1.397TrpArg: 1.397 ± 0.355
0.904TrpSer: 0.904 ± 0.241
0.493TrpThr: 0.493 ± 0.153
1.068TrpVal: 1.068 ± 0.289
0.246TrpTrp: 0.246 ± 0.141
0.575TrpTyr: 0.575 ± 0.219
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.204TyrAla: 3.204 ± 0.569
0.493TyrCys: 0.493 ± 0.213
2.301TyrAsp: 2.301 ± 0.501
1.808TyrGlu: 1.808 ± 0.435
1.643TyrPhe: 1.643 ± 0.374
2.218TyrGly: 2.218 ± 0.514
0.493TyrHis: 0.493 ± 0.177
2.136TyrIle: 2.136 ± 0.482
1.397TyrLys: 1.397 ± 0.329
2.465TyrLeu: 2.465 ± 0.339
0.739TyrMet: 0.739 ± 0.276
1.561TyrAsn: 1.561 ± 0.461
1.479TyrPro: 1.479 ± 0.431
1.972TyrGln: 1.972 ± 0.39
2.383TyrArg: 2.383 ± 0.462
1.725TyrSer: 1.725 ± 0.349
1.15TyrThr: 1.15 ± 0.246
2.218TyrVal: 2.218 ± 0.433
0.493TyrTrp: 0.493 ± 0.179
1.068TyrTyr: 1.068 ± 0.343
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 60 proteins (12172 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski