Amino acid dipepetide frequency for Hubei narna-like virus 18

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
2.217AlaAla: 2.217 ± 0.545
1.478AlaCys: 1.478 ± 1.136
2.956AlaAsp: 2.956 ± 1.148
4.435AlaGlu: 4.435 ± 1.16
2.217AlaPhe: 2.217 ± 1.67
3.695AlaGly: 3.695 ± 1.658
2.217AlaHis: 2.217 ± 0.545
4.435AlaIle: 4.435 ± 2.214
3.695AlaLys: 3.695 ± 1.658
2.956AlaLeu: 2.956 ± 1.101
0.0AlaMet: 0.0 ± 0.0
0.739AlaAsn: 0.739 ± 0.557
2.217AlaPro: 2.217 ± 0.58
3.695AlaGln: 3.695 ± 0.533
5.913AlaArg: 5.913 ± 3.328
5.174AlaSer: 5.174 ± 1.646
4.435AlaThr: 4.435 ± 1.16
2.956AlaVal: 2.956 ± 1.101
0.0AlaTrp: 0.0 ± 0.0
2.217AlaTyr: 2.217 ± 0.545
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.739CysCys: 0.739 ± 0.557
0.739CysAsp: 0.739 ± 0.568
0.739CysGlu: 0.739 ± 0.568
0.0CysPhe: 0.0 ± 0.0
2.217CysGly: 2.217 ± 0.58
0.739CysHis: 0.739 ± 0.557
0.739CysIle: 0.739 ± 0.568
2.956CysLys: 2.956 ± 0.023
0.739CysLeu: 0.739 ± 0.568
0.739CysMet: 0.739 ± 0.568
0.739CysAsn: 0.739 ± 0.568
1.478CysPro: 1.478 ± 0.012
2.217CysGln: 2.217 ± 0.58
0.739CysArg: 0.739 ± 0.557
1.478CysSer: 1.478 ± 0.012
1.478CysThr: 1.478 ± 1.136
1.478CysVal: 1.478 ± 0.012
0.0CysTrp: 0.0 ± 0.0
1.478CysTyr: 1.478 ± 1.136
0.0CysXaa: 0.0 ± 0.0
Asp
2.956AspAla: 2.956 ± 1.101
0.739AspCys: 0.739 ± 0.568
5.174AspAsp: 5.174 ± 0.603
1.478AspGlu: 1.478 ± 0.012
2.956AspPhe: 2.956 ± 2.226
2.956AspGly: 2.956 ± 1.101
0.739AspHis: 0.739 ± 0.568
8.13AspIle: 8.13 ± 0.498
1.478AspLys: 1.478 ± 0.012
5.913AspLeu: 5.913 ± 2.203
0.0AspMet: 0.0 ± 0.0
2.956AspAsn: 2.956 ± 0.023
2.217AspPro: 2.217 ± 1.67
2.956AspGln: 2.956 ± 1.101
2.956AspArg: 2.956 ± 1.148
3.695AspSer: 3.695 ± 2.841
1.478AspThr: 1.478 ± 1.136
2.217AspVal: 2.217 ± 0.545
0.0AspTrp: 0.0 ± 0.0
3.695AspTyr: 3.695 ± 1.658
0.0AspXaa: 0.0 ± 0.0
Glu
2.956GluAla: 2.956 ± 0.023
1.478GluCys: 1.478 ± 1.136
1.478GluAsp: 1.478 ± 1.113
2.217GluGlu: 2.217 ± 0.58
0.0GluPhe: 0.0 ± 0.0
2.956GluGly: 2.956 ± 1.148
1.478GluHis: 1.478 ± 1.136
1.478GluIle: 1.478 ± 0.012
2.217GluLys: 2.217 ± 0.545
3.695GluLeu: 3.695 ± 1.716
0.0GluMet: 0.0 ± 0.0
2.956GluAsn: 2.956 ± 0.023
0.739GluPro: 0.739 ± 0.557
0.739GluGln: 0.739 ± 0.557
4.435GluArg: 4.435 ± 2.214
3.695GluSer: 3.695 ± 0.591
2.217GluThr: 2.217 ± 0.58
2.956GluVal: 2.956 ± 2.273
1.478GluTrp: 1.478 ± 0.012
2.956GluTyr: 2.956 ± 0.023
0.0GluXaa: 0.0 ± 0.0
Phe
2.956PheAla: 2.956 ± 2.226
0.739PheCys: 0.739 ± 0.557
4.435PheAsp: 4.435 ± 2.214
0.739PheGlu: 0.739 ± 0.557
0.0PhePhe: 0.0 ± 0.0
0.739PheGly: 0.739 ± 0.568
2.217PheHis: 2.217 ± 0.58
2.956PheIle: 2.956 ± 1.148
2.956PheLys: 2.956 ± 1.101
1.478PheLeu: 1.478 ± 0.012
0.0PheMet: 0.0 ± 0.0
1.478PheAsn: 1.478 ± 1.136
2.217PhePro: 2.217 ± 0.545
2.217PheGln: 2.217 ± 1.67
4.435PheArg: 4.435 ± 2.284
2.956PheSer: 2.956 ± 1.101
1.478PheThr: 1.478 ± 0.012
2.217PheVal: 2.217 ± 1.704
0.0PheTrp: 0.0 ± 0.0
0.739PheTyr: 0.739 ± 0.568
0.0PheXaa: 0.0 ± 0.0
Gly
0.0GlyAla: 0.0 ± 0.0
2.217GlyCys: 2.217 ± 0.58
6.652GlyAsp: 6.652 ± 1.739
0.739GlyGlu: 0.739 ± 0.568
2.956GlyPhe: 2.956 ± 0.023
3.695GlyGly: 3.695 ± 2.783
2.956GlyHis: 2.956 ± 1.148
5.174GlyIle: 5.174 ± 0.603
2.217GlyLys: 2.217 ± 0.545
3.695GlyLeu: 3.695 ± 0.591
0.0GlyMet: 0.0 ± 0.0
4.435GlyAsn: 4.435 ± 1.09
1.478GlyPro: 1.478 ± 0.012
2.217GlyGln: 2.217 ± 0.58
2.956GlyArg: 2.956 ± 1.101
2.956GlySer: 2.956 ± 1.148
5.913GlyThr: 5.913 ± 1.078
2.956GlyVal: 2.956 ± 0.023
1.478GlyTrp: 1.478 ± 0.012
4.435GlyTyr: 4.435 ± 0.035
0.0GlyXaa: 0.0 ± 0.0
His
0.739HisAla: 0.739 ± 0.557
0.0HisCys: 0.0 ± 0.0
0.739HisAsp: 0.739 ± 0.568
2.956HisGlu: 2.956 ± 2.226
0.0HisPhe: 0.0 ± 0.0
1.478HisGly: 1.478 ± 1.136
0.0HisHis: 0.0 ± 0.0
1.478HisIle: 1.478 ± 1.136
2.956HisLys: 2.956 ± 1.101
3.695HisLeu: 3.695 ± 1.716
0.0HisMet: 0.0 ± 0.0
2.217HisAsn: 2.217 ± 0.58
2.956HisPro: 2.956 ± 1.148
0.739HisGln: 0.739 ± 0.557
5.174HisArg: 5.174 ± 1.646
2.217HisSer: 2.217 ± 0.58
2.956HisThr: 2.956 ± 1.148
2.217HisVal: 2.217 ± 0.58
0.739HisTrp: 0.739 ± 0.568
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
1.478IleAla: 1.478 ± 0.012
2.217IleCys: 2.217 ± 1.704
2.217IleAsp: 2.217 ± 0.545
2.956IleGlu: 2.956 ± 1.148
1.478IlePhe: 1.478 ± 0.012
3.695IleGly: 3.695 ± 1.658
2.217IleHis: 2.217 ± 1.67
3.695IleIle: 3.695 ± 0.591
2.217IleLys: 2.217 ± 0.545
4.435IleLeu: 4.435 ± 1.16
0.0IleMet: 0.0 ± 0.367
1.478IleAsn: 1.478 ± 0.012
5.174IlePro: 5.174 ± 2.771
2.217IleGln: 2.217 ± 0.58
14.043IleArg: 14.043 ± 1.798
4.435IleSer: 4.435 ± 2.284
5.913IleThr: 5.913 ± 1.171
6.652IleVal: 6.652 ± 0.615
0.0IleTrp: 0.0 ± 0.0
2.217IleTyr: 2.217 ± 1.67
0.0IleXaa: 0.0 ± 0.0
Lys
2.217LysAla: 2.217 ± 1.67
0.739LysCys: 0.739 ± 0.568
0.739LysAsp: 0.739 ± 0.557
2.217LysGlu: 2.217 ± 0.545
2.956LysPhe: 2.956 ± 1.101
3.695LysGly: 3.695 ± 1.658
4.435LysHis: 4.435 ± 1.16
2.956LysIle: 2.956 ± 1.148
2.217LysLys: 2.217 ± 0.545
3.695LysLeu: 3.695 ± 0.533
1.478LysMet: 1.478 ± 1.113
0.0LysAsn: 0.0 ± 0.0
3.695LysPro: 3.695 ± 0.591
0.0LysGln: 0.0 ± 0.0
2.956LysArg: 2.956 ± 0.023
2.217LysSer: 2.217 ± 1.67
1.478LysThr: 1.478 ± 0.012
7.391LysVal: 7.391 ± 1.183
0.0LysTrp: 0.0 ± 0.0
2.217LysTyr: 2.217 ± 0.545
0.0LysXaa: 0.0 ± 0.0
Leu
8.13LeuAla: 8.13 ± 1.623
3.695LeuCys: 3.695 ± 0.591
4.435LeuAsp: 4.435 ± 3.339
4.435LeuGlu: 4.435 ± 1.16
2.217LeuPhe: 2.217 ± 1.704
2.956LeuGly: 2.956 ± 0.023
2.956LeuHis: 2.956 ± 0.023
4.435LeuIle: 4.435 ± 0.035
2.956LeuLys: 2.956 ± 2.273
8.13LeuLeu: 8.13 ± 0.626
1.478LeuMet: 1.478 ± 1.136
2.217LeuAsn: 2.217 ± 0.545
7.391LeuPro: 7.391 ± 3.432
0.0LeuGln: 0.0 ± 0.0
7.391LeuArg: 7.391 ± 1.067
9.608LeuSer: 9.608 ± 1.611
2.956LeuThr: 2.956 ± 0.023
7.391LeuVal: 7.391 ± 2.308
2.956LeuTrp: 2.956 ± 0.023
1.478LeuTyr: 1.478 ± 1.113
0.0LeuXaa: 0.0 ± 0.0
Met
0.739MetAla: 0.739 ± 0.557
0.0MetCys: 0.0 ± 0.0
2.217MetAsp: 2.217 ± 0.58
2.217MetGlu: 2.217 ± 0.545
2.217MetPhe: 2.217 ± 1.67
0.739MetGly: 0.739 ± 0.557
0.0MetHis: 0.0 ± 0.0
0.739MetIle: 0.739 ± 0.568
0.0MetLys: 0.0 ± 0.0
3.695MetLeu: 3.695 ± 0.533
0.0MetMet: 0.0 ± 0.0
0.0MetAsn: 0.0 ± 0.0
0.0MetPro: 0.0 ± 0.0
1.478MetGln: 1.478 ± 0.012
0.739MetArg: 0.739 ± 0.568
1.478MetSer: 1.478 ± 1.113
1.478MetThr: 1.478 ± 1.136
0.0MetVal: 0.0 ± 0.0
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
3.695AsnAla: 3.695 ± 1.658
0.0AsnCys: 0.0 ± 0.0
1.478AsnAsp: 1.478 ± 1.136
0.0AsnGlu: 0.0 ± 0.0
1.478AsnPhe: 1.478 ± 1.113
1.478AsnGly: 1.478 ± 1.136
0.0AsnHis: 0.0 ± 0.0
2.217AsnIle: 2.217 ± 1.704
3.695AsnLys: 3.695 ± 0.533
4.435AsnLeu: 4.435 ± 1.16
1.478AsnMet: 1.478 ± 0.012
0.739AsnAsn: 0.739 ± 0.557
0.739AsnPro: 0.739 ± 0.568
0.0AsnGln: 0.0 ± 0.0
4.435AsnArg: 4.435 ± 0.035
2.217AsnSer: 2.217 ± 1.704
2.956AsnThr: 2.956 ± 1.148
3.695AsnVal: 3.695 ± 0.533
1.478AsnTrp: 1.478 ± 0.012
2.217AsnTyr: 2.217 ± 1.67
0.0AsnXaa: 0.0 ± 0.0
Pro
2.956ProAla: 2.956 ± 1.101
0.0ProCys: 0.0 ± 0.0
2.956ProAsp: 2.956 ± 1.148
3.695ProGlu: 3.695 ± 0.591
3.695ProPhe: 3.695 ± 0.591
2.956ProGly: 2.956 ± 0.023
1.478ProHis: 1.478 ± 0.012
4.435ProIle: 4.435 ± 2.214
2.217ProLys: 2.217 ± 0.545
3.695ProLeu: 3.695 ± 0.533
0.739ProMet: 0.739 ± 0.557
4.435ProAsn: 4.435 ± 1.09
1.478ProPro: 1.478 ± 0.012
0.739ProGln: 0.739 ± 0.568
5.174ProArg: 5.174 ± 0.603
1.478ProSer: 1.478 ± 0.012
2.217ProThr: 2.217 ± 0.545
4.435ProVal: 4.435 ± 1.16
0.739ProTrp: 0.739 ± 0.568
2.956ProTyr: 2.956 ± 2.226
0.0ProXaa: 0.0 ± 0.0
Gln
1.478GlnAla: 1.478 ± 0.012
0.0GlnCys: 0.0 ± 0.0
1.478GlnAsp: 1.478 ± 0.012
0.0GlnGlu: 0.0 ± 0.0
1.478GlnPhe: 1.478 ± 0.012
1.478GlnGly: 1.478 ± 1.136
1.478GlnHis: 1.478 ± 1.113
4.435GlnIle: 4.435 ± 0.035
2.217GlnLys: 2.217 ± 0.545
5.913GlnLeu: 5.913 ± 1.171
1.478GlnMet: 1.478 ± 0.012
0.739GlnAsn: 0.739 ± 0.557
0.0GlnPro: 0.0 ± 0.0
0.739GlnGln: 0.739 ± 0.557
2.956GlnArg: 2.956 ± 1.148
0.739GlnSer: 0.739 ± 0.568
1.478GlnThr: 1.478 ± 0.012
0.739GlnVal: 0.739 ± 0.557
1.478GlnTrp: 1.478 ± 0.012
1.478GlnTyr: 1.478 ± 0.012
0.0GlnXaa: 0.0 ± 0.0
Arg
7.391ArgAla: 7.391 ± 0.058
1.478ArgCys: 1.478 ± 1.113
5.174ArgAsp: 5.174 ± 2.771
3.695ArgGlu: 3.695 ± 2.841
2.217ArgPhe: 2.217 ± 1.704
5.913ArgGly: 5.913 ± 0.047
2.956ArgHis: 2.956 ± 2.273
5.174ArgIle: 5.174 ± 0.522
5.174ArgLys: 5.174 ± 1.646
6.652ArgLeu: 6.652 ± 1.739
4.435ArgMet: 4.435 ± 1.394
2.956ArgAsn: 2.956 ± 1.148
5.174ArgPro: 5.174 ± 0.522
4.435ArgGln: 4.435 ± 1.09
8.869ArgArg: 8.869 ± 2.18
5.913ArgSer: 5.913 ± 2.203
3.695ArgThr: 3.695 ± 1.716
8.13ArgVal: 8.13 ± 0.498
3.695ArgTrp: 3.695 ± 0.533
0.739ArgTyr: 0.739 ± 0.568
0.0ArgXaa: 0.0 ± 0.0
Ser
5.913SerAla: 5.913 ± 2.296
2.956SerCys: 2.956 ± 1.148
3.695SerAsp: 3.695 ± 1.658
2.956SerGlu: 2.956 ± 2.226
4.435SerPhe: 4.435 ± 1.16
5.913SerGly: 5.913 ± 0.047
3.695SerHis: 3.695 ± 0.533
3.695SerIle: 3.695 ± 0.533
2.217SerLys: 2.217 ± 0.58
5.913SerLeu: 5.913 ± 2.203
0.739SerMet: 0.739 ± 0.568
2.956SerAsn: 2.956 ± 1.148
4.435SerPro: 4.435 ± 1.09
2.217SerGln: 2.217 ± 0.58
5.913SerArg: 5.913 ± 1.078
6.652SerSer: 6.652 ± 0.51
1.478SerThr: 1.478 ± 0.012
4.435SerVal: 4.435 ± 1.16
0.739SerTrp: 0.739 ± 0.568
1.478SerTyr: 1.478 ± 0.012
0.0SerXaa: 0.0 ± 0.0
Thr
4.435ThrAla: 4.435 ± 0.035
1.478ThrCys: 1.478 ± 0.012
2.956ThrAsp: 2.956 ± 1.101
2.217ThrGlu: 2.217 ± 0.58
1.478ThrPhe: 1.478 ± 0.012
5.174ThrGly: 5.174 ± 2.852
0.0ThrHis: 0.0 ± 0.0
2.956ThrIle: 2.956 ± 0.023
0.739ThrLys: 0.739 ± 0.557
5.913ThrLeu: 5.913 ± 2.296
0.739ThrMet: 0.739 ± 0.557
3.695ThrAsn: 3.695 ± 0.591
2.217ThrPro: 2.217 ± 0.545
1.478ThrGln: 1.478 ± 1.136
5.174ThrArg: 5.174 ± 1.728
1.478ThrSer: 1.478 ± 0.012
5.174ThrThr: 5.174 ± 2.852
6.652ThrVal: 6.652 ± 0.615
0.739ThrTrp: 0.739 ± 0.557
0.739ThrTyr: 0.739 ± 0.557
0.0ThrXaa: 0.0 ± 0.0
Val
2.956ValAla: 2.956 ± 1.101
1.478ValCys: 1.478 ± 0.012
2.217ValAsp: 2.217 ± 0.545
3.695ValGlu: 3.695 ± 0.591
4.435ValPhe: 4.435 ± 1.16
5.174ValGly: 5.174 ± 0.603
2.956ValHis: 2.956 ± 1.148
6.652ValIle: 6.652 ± 0.615
2.956ValLys: 2.956 ± 1.148
6.652ValLeu: 6.652 ± 0.615
2.217ValMet: 2.217 ± 0.545
0.739ValAsn: 0.739 ± 0.568
5.913ValPro: 5.913 ± 1.078
2.956ValGln: 2.956 ± 2.273
4.435ValArg: 4.435 ± 2.284
8.13ValSer: 8.13 ± 1.751
4.435ValThr: 4.435 ± 2.214
4.435ValVal: 4.435 ± 0.035
0.739ValTrp: 0.739 ± 0.557
2.956ValTyr: 2.956 ± 1.148
0.0ValXaa: 0.0 ± 0.0
Trp
0.739TrpAla: 0.739 ± 0.557
0.0TrpCys: 0.0 ± 0.0
0.739TrpAsp: 0.739 ± 0.568
0.739TrpGlu: 0.739 ± 0.568
0.0TrpPhe: 0.0 ± 0.0
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
1.478TrpLys: 1.478 ± 0.012
2.956TrpLeu: 2.956 ± 1.101
0.739TrpMet: 0.739 ± 0.568
0.739TrpAsn: 0.739 ± 0.568
0.739TrpPro: 0.739 ± 0.557
0.739TrpGln: 0.739 ± 0.568
0.739TrpArg: 0.739 ± 0.568
2.956TrpSer: 2.956 ± 0.023
0.0TrpThr: 0.0 ± 0.0
2.217TrpVal: 2.217 ± 0.545
0.0TrpTrp: 0.0 ± 0.0
1.478TrpTyr: 1.478 ± 0.012
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.695TyrAla: 3.695 ± 1.658
0.0TyrCys: 0.0 ± 0.0
2.217TyrAsp: 2.217 ± 0.58
0.0TyrGlu: 0.0 ± 0.0
0.739TyrPhe: 0.739 ± 0.557
2.217TyrGly: 2.217 ± 0.58
0.739TyrHis: 0.739 ± 0.557
3.695TyrIle: 3.695 ± 0.533
0.739TyrLys: 0.739 ± 0.568
2.956TyrLeu: 2.956 ± 1.101
0.739TyrMet: 0.739 ± 0.557
2.217TyrAsn: 2.217 ± 0.58
2.217TyrPro: 2.217 ± 0.545
0.0TyrGln: 0.0 ± 0.0
4.435TyrArg: 4.435 ± 1.09
2.956TyrSer: 2.956 ± 2.226
2.217TyrThr: 2.217 ± 0.545
2.956TyrVal: 2.956 ± 0.023
0.739TyrTrp: 0.739 ± 0.568
0.739TyrTyr: 0.739 ± 0.557
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (1354 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski