Amino acid dipepetide frequency for Changjiang tombus-like virus 2

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.31AlaAla: 4.31 ± 0.109
1.437AlaCys: 1.437 ± 0.696
2.874AlaAsp: 2.874 ± 0.805
1.437AlaGlu: 1.437 ± 0.696
1.437AlaPhe: 1.437 ± 0.696
5.747AlaGly: 5.747 ± 3.806
1.437AlaHis: 1.437 ± 1.501
4.31AlaIle: 4.31 ± 2.306
4.31AlaLys: 4.31 ± 0.109
2.874AlaLeu: 2.874 ± 1.392
0.0AlaMet: 0.0 ± 0.0
4.31AlaAsn: 4.31 ± 0.109
4.31AlaPro: 4.31 ± 0.109
2.874AlaGln: 2.874 ± 1.392
4.31AlaArg: 4.31 ± 2.306
4.31AlaSer: 4.31 ± 2.088
1.437AlaThr: 1.437 ± 0.696
4.31AlaVal: 4.31 ± 2.088
2.874AlaTrp: 2.874 ± 3.002
1.437AlaTyr: 1.437 ± 0.696
0.0AlaXaa: 0.0 ± 0.0
Cys
2.874CysAla: 2.874 ± 1.392
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
1.437CysGlu: 1.437 ± 0.696
0.0CysPhe: 0.0 ± 0.0
1.437CysGly: 1.437 ± 0.696
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
4.31CysLys: 4.31 ± 0.109
1.437CysLeu: 1.437 ± 0.696
1.437CysMet: 1.437 ± 0.696
1.437CysAsn: 1.437 ± 0.696
0.0CysPro: 0.0 ± 0.0
2.874CysGln: 2.874 ± 0.805
0.0CysArg: 0.0 ± 0.0
1.437CysSer: 1.437 ± 0.696
1.437CysThr: 1.437 ± 0.696
1.437CysVal: 1.437 ± 1.501
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
4.31AspAla: 4.31 ± 2.088
2.874AspCys: 2.874 ± 1.392
5.747AspAsp: 5.747 ± 0.587
0.0AspGlu: 0.0 ± 0.0
1.437AspPhe: 1.437 ± 0.696
2.874AspGly: 2.874 ± 1.392
0.0AspHis: 0.0 ± 0.0
2.874AspIle: 2.874 ± 0.805
4.31AspLys: 4.31 ± 0.109
4.31AspLeu: 4.31 ± 0.109
2.874AspMet: 2.874 ± 0.805
2.874AspAsn: 2.874 ± 0.805
2.874AspPro: 2.874 ± 0.805
5.747AspGln: 5.747 ± 0.587
1.437AspArg: 1.437 ± 0.696
1.437AspSer: 1.437 ± 0.696
1.437AspThr: 1.437 ± 0.696
2.874AspVal: 2.874 ± 0.805
0.0AspTrp: 0.0 ± 0.0
1.437AspTyr: 1.437 ± 0.696
0.0AspXaa: 0.0 ± 0.0
Glu
0.0GluAla: 0.0 ± 0.0
0.0GluCys: 0.0 ± 0.0
1.437GluAsp: 1.437 ± 0.696
1.437GluGlu: 1.437 ± 1.501
5.747GluPhe: 5.747 ± 2.784
2.874GluGly: 2.874 ± 1.392
2.874GluHis: 2.874 ± 1.392
1.437GluIle: 1.437 ± 0.696
1.437GluLys: 1.437 ± 0.696
4.31GluLeu: 4.31 ± 0.109
0.0GluMet: 0.0 ± 0.0
2.874GluAsn: 2.874 ± 0.805
2.874GluPro: 2.874 ± 1.392
4.31GluGln: 4.31 ± 2.088
2.874GluArg: 2.874 ± 1.392
0.0GluSer: 0.0 ± 0.0
2.874GluThr: 2.874 ± 0.805
5.747GluVal: 5.747 ± 1.61
0.0GluTrp: 0.0 ± 0.0
2.874GluTyr: 2.874 ± 0.805
0.0GluXaa: 0.0 ± 0.0
Phe
2.874PheAla: 2.874 ± 1.392
2.874PheCys: 2.874 ± 0.805
2.874PheAsp: 2.874 ± 1.392
5.747PheGlu: 5.747 ± 0.587
1.437PhePhe: 1.437 ± 1.501
7.184PheGly: 7.184 ± 1.283
0.0PheHis: 0.0 ± 0.0
4.31PheIle: 4.31 ± 2.306
4.31PheLys: 4.31 ± 2.088
0.0PheLeu: 0.0 ± 0.0
1.437PheMet: 1.437 ± 1.501
2.874PheAsn: 2.874 ± 1.392
0.0PhePro: 0.0 ± 0.0
2.874PheGln: 2.874 ± 3.002
1.437PheArg: 1.437 ± 0.696
2.874PheSer: 2.874 ± 1.392
1.437PheThr: 1.437 ± 0.696
7.184PheVal: 7.184 ± 0.914
1.437PheTrp: 1.437 ± 0.696
2.874PheTyr: 2.874 ± 1.392
0.0PheXaa: 0.0 ± 0.0
Gly
4.31GlyAla: 4.31 ± 2.306
1.437GlyCys: 1.437 ± 0.696
4.31GlyAsp: 4.31 ± 2.088
4.31GlyGlu: 4.31 ± 2.088
2.874GlyPhe: 2.874 ± 1.392
1.437GlyGly: 1.437 ± 0.696
2.874GlyHis: 2.874 ± 1.392
5.747GlyIle: 5.747 ± 2.784
1.437GlyLys: 1.437 ± 0.696
5.747GlyLeu: 5.747 ± 3.806
0.0GlyMet: 0.0 ± 0.0
7.184GlyAsn: 7.184 ± 3.11
2.874GlyPro: 2.874 ± 0.805
2.874GlyGln: 2.874 ± 0.805
10.057GlyArg: 10.057 ± 0.478
7.184GlySer: 7.184 ± 0.914
4.31GlyThr: 4.31 ± 4.502
5.747GlyVal: 5.747 ± 0.587
1.437GlyTrp: 1.437 ± 0.696
1.437GlyTyr: 1.437 ± 1.501
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
1.437HisCys: 1.437 ± 1.501
4.31HisAsp: 4.31 ± 2.088
0.0HisGlu: 0.0 ± 0.0
0.0HisPhe: 0.0 ± 0.0
2.874HisGly: 2.874 ± 1.392
0.0HisHis: 0.0 ± 0.0
2.874HisIle: 2.874 ± 1.392
2.874HisLys: 2.874 ± 1.392
2.874HisLeu: 2.874 ± 0.805
0.0HisMet: 0.0 ± 0.0
2.874HisAsn: 2.874 ± 1.392
0.0HisPro: 0.0 ± 0.0
1.437HisGln: 1.437 ± 0.696
0.0HisArg: 0.0 ± 0.0
2.874HisSer: 2.874 ± 0.805
0.0HisThr: 0.0 ± 0.0
1.437HisVal: 1.437 ± 0.696
0.0HisTrp: 0.0 ± 0.0
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
2.874IleAla: 2.874 ± 0.805
1.437IleCys: 1.437 ± 0.696
2.874IleAsp: 2.874 ± 1.392
5.747IleGlu: 5.747 ± 2.784
4.31IlePhe: 4.31 ± 0.109
0.0IleGly: 0.0 ± 0.0
1.437IleHis: 1.437 ± 0.696
8.621IleIle: 8.621 ± 0.218
0.0IleLys: 0.0 ± 0.0
0.0IleLeu: 0.0 ± 0.0
0.0IleMet: 0.0 ± 0.0
5.747IleAsn: 5.747 ± 0.587
4.31IlePro: 4.31 ± 0.109
1.437IleGln: 1.437 ± 0.696
4.31IleArg: 4.31 ± 2.306
4.31IleSer: 4.31 ± 2.306
1.437IleThr: 1.437 ± 0.696
4.31IleVal: 4.31 ± 0.109
1.437IleTrp: 1.437 ± 0.696
1.437IleTyr: 1.437 ± 0.696
0.0IleXaa: 0.0 ± 0.0
Lys
1.437LysAla: 1.437 ± 0.696
2.874LysCys: 2.874 ± 1.392
2.874LysAsp: 2.874 ± 1.392
1.437LysGlu: 1.437 ± 0.696
2.874LysPhe: 2.874 ± 1.392
5.747LysGly: 5.747 ± 0.587
2.874LysHis: 2.874 ± 1.392
2.874LysIle: 2.874 ± 1.392
1.437LysLys: 1.437 ± 0.696
2.874LysLeu: 2.874 ± 1.392
2.874LysMet: 2.874 ± 0.805
0.0LysAsn: 0.0 ± 0.0
2.874LysPro: 2.874 ± 1.392
0.0LysGln: 0.0 ± 0.0
4.31LysArg: 4.31 ± 0.109
4.31LysSer: 4.31 ± 0.109
5.747LysThr: 5.747 ± 3.806
1.437LysVal: 1.437 ± 0.696
0.0LysTrp: 0.0 ± 0.0
4.31LysTyr: 4.31 ± 2.088
0.0LysXaa: 0.0 ± 0.0
Leu
7.184LeuAla: 7.184 ± 3.11
1.437LeuCys: 1.437 ± 0.696
5.747LeuAsp: 5.747 ± 0.587
1.437LeuGlu: 1.437 ± 0.696
4.31LeuPhe: 4.31 ± 0.109
7.184LeuGly: 7.184 ± 1.283
2.874LeuHis: 2.874 ± 1.392
0.0LeuIle: 0.0 ± 0.0
8.621LeuLys: 8.621 ± 4.176
7.184LeuLeu: 7.184 ± 0.914
1.437LeuMet: 1.437 ± 0.696
7.184LeuAsn: 7.184 ± 5.307
4.31LeuPro: 4.31 ± 0.109
0.0LeuGln: 0.0 ± 0.0
5.747LeuArg: 5.747 ± 0.587
5.747LeuSer: 5.747 ± 1.61
4.31LeuThr: 4.31 ± 2.306
4.31LeuVal: 4.31 ± 0.109
0.0LeuTrp: 0.0 ± 0.0
2.874LeuTyr: 2.874 ± 0.805
0.0LeuXaa: 0.0 ± 0.0
Met
1.437MetAla: 1.437 ± 1.501
2.874MetCys: 2.874 ± 1.392
0.0MetAsp: 0.0 ± 0.0
0.0MetGlu: 0.0 ± 0.0
0.0MetPhe: 0.0 ± 0.0
1.437MetGly: 1.437 ± 0.696
0.0MetHis: 0.0 ± 0.0
1.437MetIle: 1.437 ± 1.501
1.437MetLys: 1.437 ± 0.696
1.437MetLeu: 1.437 ± 0.696
1.437MetMet: 1.437 ± 0.696
1.437MetAsn: 1.437 ± 0.696
0.0MetPro: 0.0 ± 0.0
0.0MetGln: 0.0 ± 0.0
1.437MetArg: 1.437 ± 1.501
4.31MetSer: 4.31 ± 2.088
1.437MetThr: 1.437 ± 0.696
1.437MetVal: 1.437 ± 1.501
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
5.747AsnAla: 5.747 ± 1.61
0.0AsnCys: 0.0 ± 0.0
1.437AsnAsp: 1.437 ± 0.696
2.874AsnGlu: 2.874 ± 3.002
4.31AsnPhe: 4.31 ± 2.306
4.31AsnGly: 4.31 ± 0.109
1.437AsnHis: 1.437 ± 0.696
4.31AsnIle: 4.31 ± 0.109
1.437AsnLys: 1.437 ± 0.696
10.057AsnLeu: 10.057 ± 1.719
0.0AsnMet: 0.0 ± 0.652
2.874AsnAsn: 2.874 ± 1.392
2.874AsnPro: 2.874 ± 0.805
0.0AsnGln: 0.0 ± 0.0
0.0AsnArg: 0.0 ± 0.0
5.747AsnSer: 5.747 ± 2.784
7.184AsnThr: 7.184 ± 3.11
2.874AsnVal: 2.874 ± 0.805
0.0AsnTrp: 0.0 ± 0.0
1.437AsnTyr: 1.437 ± 0.696
0.0AsnXaa: 0.0 ± 0.0
Pro
1.437ProAla: 1.437 ± 0.696
0.0ProCys: 0.0 ± 0.0
1.437ProAsp: 1.437 ± 1.501
1.437ProGlu: 1.437 ± 0.696
0.0ProPhe: 0.0 ± 0.0
4.31ProGly: 4.31 ± 4.502
0.0ProHis: 0.0 ± 0.0
2.874ProIle: 2.874 ± 1.392
1.437ProLys: 1.437 ± 0.696
2.874ProLeu: 2.874 ± 0.805
0.0ProMet: 0.0 ± 0.0
1.437ProAsn: 1.437 ± 0.696
2.874ProPro: 2.874 ± 0.805
2.874ProGln: 2.874 ± 3.002
8.621ProArg: 8.621 ± 0.218
2.874ProSer: 2.874 ± 3.002
1.437ProThr: 1.437 ± 0.696
7.184ProVal: 7.184 ± 1.283
0.0ProTrp: 0.0 ± 0.0
2.874ProTyr: 2.874 ± 1.392
0.0ProXaa: 0.0 ± 0.0
Gln
1.437GlnAla: 1.437 ± 0.696
1.437GlnCys: 1.437 ± 0.696
0.0GlnAsp: 0.0 ± 0.0
2.874GlnGlu: 2.874 ± 0.805
1.437GlnPhe: 1.437 ± 0.696
2.874GlnGly: 2.874 ± 0.805
4.31GlnHis: 4.31 ± 0.109
2.874GlnIle: 2.874 ± 1.392
2.874GlnLys: 2.874 ± 0.805
4.31GlnLeu: 4.31 ± 2.306
1.437GlnMet: 1.437 ± 0.93
0.0GlnAsn: 0.0 ± 0.0
4.31GlnPro: 4.31 ± 0.109
1.437GlnGln: 1.437 ± 0.696
2.874GlnArg: 2.874 ± 3.002
2.874GlnSer: 2.874 ± 0.805
1.437GlnThr: 1.437 ± 0.696
0.0GlnVal: 0.0 ± 0.0
0.0GlnTrp: 0.0 ± 0.0
1.437GlnTyr: 1.437 ± 0.696
0.0GlnXaa: 0.0 ± 0.0
Arg
7.184ArgAla: 7.184 ± 3.11
0.0ArgCys: 0.0 ± 0.0
4.31ArgAsp: 4.31 ± 0.109
2.874ArgGlu: 2.874 ± 0.805
7.184ArgPhe: 7.184 ± 0.914
2.874ArgGly: 2.874 ± 1.392
0.0ArgHis: 0.0 ± 0.0
1.437ArgIle: 1.437 ± 0.696
2.874ArgLys: 2.874 ± 0.805
4.31ArgLeu: 4.31 ± 0.109
4.31ArgMet: 4.31 ± 2.088
4.31ArgAsn: 4.31 ± 2.088
1.437ArgPro: 1.437 ± 0.696
2.874ArgGln: 2.874 ± 1.392
5.747ArgArg: 5.747 ± 0.587
4.31ArgSer: 4.31 ± 0.109
4.31ArgThr: 4.31 ± 2.306
4.31ArgVal: 4.31 ± 0.109
2.874ArgTrp: 2.874 ± 1.392
2.874ArgTyr: 2.874 ± 0.805
0.0ArgXaa: 0.0 ± 0.0
Ser
4.31SerAla: 4.31 ± 0.109
1.437SerCys: 1.437 ± 1.501
0.0SerAsp: 0.0 ± 0.0
2.874SerGlu: 2.874 ± 1.392
4.31SerPhe: 4.31 ± 0.109
7.184SerGly: 7.184 ± 0.914
0.0SerHis: 0.0 ± 0.0
4.31SerIle: 4.31 ± 2.088
1.437SerLys: 1.437 ± 0.696
8.621SerLeu: 8.621 ± 2.415
1.437SerMet: 1.437 ± 0.696
2.874SerAsn: 2.874 ± 3.002
4.31SerPro: 4.31 ± 0.109
1.437SerGln: 1.437 ± 1.501
7.184SerArg: 7.184 ± 3.48
2.874SerSer: 2.874 ± 0.805
1.437SerThr: 1.437 ± 0.696
8.621SerVal: 8.621 ± 0.218
0.0SerTrp: 0.0 ± 0.0
4.31SerTyr: 4.31 ± 0.109
0.0SerXaa: 0.0 ± 0.0
Thr
5.747ThrAla: 5.747 ± 0.587
0.0ThrCys: 0.0 ± 0.0
2.874ThrAsp: 2.874 ± 0.805
1.437ThrGlu: 1.437 ± 1.501
4.31ThrPhe: 4.31 ± 2.306
4.31ThrGly: 4.31 ± 2.306
2.874ThrHis: 2.874 ± 1.392
0.0ThrIle: 0.0 ± 0.0
2.874ThrLys: 2.874 ± 0.805
2.874ThrLeu: 2.874 ± 1.392
0.0ThrMet: 0.0 ± 0.0
0.0ThrAsn: 0.0 ± 0.0
2.874ThrPro: 2.874 ± 3.002
2.874ThrGln: 2.874 ± 3.002
2.874ThrArg: 2.874 ± 1.392
2.874ThrSer: 2.874 ± 1.392
0.0ThrThr: 0.0 ± 0.0
4.31ThrVal: 4.31 ± 2.306
0.0ThrTrp: 0.0 ± 0.0
2.874ThrTyr: 2.874 ± 0.805
0.0ThrXaa: 0.0 ± 0.0
Val
2.874ValAla: 2.874 ± 1.392
0.0ValCys: 0.0 ± 0.0
5.747ValAsp: 5.747 ± 3.806
4.31ValGlu: 4.31 ± 2.088
5.747ValPhe: 5.747 ± 0.587
8.621ValGly: 8.621 ± 0.218
2.874ValHis: 2.874 ± 0.805
1.437ValIle: 1.437 ± 0.696
2.874ValLys: 2.874 ± 0.805
5.747ValLeu: 5.747 ± 2.784
1.437ValMet: 1.437 ± 0.696
4.31ValAsn: 4.31 ± 0.109
2.874ValPro: 2.874 ± 3.002
1.437ValGln: 1.437 ± 0.696
2.874ValArg: 2.874 ± 0.805
7.184ValSer: 7.184 ± 3.11
2.874ValThr: 2.874 ± 0.805
1.437ValVal: 1.437 ± 0.696
2.874ValTrp: 2.874 ± 0.805
1.437ValTyr: 1.437 ± 0.696
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.0TrpCys: 0.0 ± 0.0
0.0TrpAsp: 0.0 ± 0.0
0.0TrpGlu: 0.0 ± 0.0
1.437TrpPhe: 1.437 ± 0.696
1.437TrpGly: 1.437 ± 0.696
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
0.0TrpLys: 0.0 ± 0.0
5.747TrpLeu: 5.747 ± 0.587
0.0TrpMet: 0.0 ± 0.0
1.437TrpAsn: 1.437 ± 1.501
0.0TrpPro: 0.0 ± 0.0
1.437TrpGln: 1.437 ± 1.501
1.437TrpArg: 1.437 ± 0.696
0.0TrpSer: 0.0 ± 0.0
0.0TrpThr: 0.0 ± 0.0
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.0TyrAla: 0.0 ± 0.0
0.0TyrCys: 0.0 ± 0.0
2.874TyrAsp: 2.874 ± 1.392
4.31TyrGlu: 4.31 ± 2.088
2.874TyrPhe: 2.874 ± 1.392
2.874TyrGly: 2.874 ± 3.002
0.0TyrHis: 0.0 ± 0.0
4.31TyrIle: 4.31 ± 2.306
2.874TyrLys: 2.874 ± 1.392
4.31TyrLeu: 4.31 ± 0.109
0.0TyrMet: 0.0 ± 0.0
4.31TyrAsn: 4.31 ± 0.109
0.0TyrPro: 0.0 ± 0.0
1.437TyrGln: 1.437 ± 0.696
2.874TyrArg: 2.874 ± 1.392
1.437TyrSer: 1.437 ± 0.696
1.437TyrThr: 1.437 ± 0.696
0.0TyrVal: 0.0 ± 0.0
0.0TyrTrp: 0.0 ± 0.0
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (697 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski