Amino acid dipepetide frequency for Gallionella capsiferriformans (strain ES-2) (Gallionella ferruginea capsiferriformans (strain ES-2))

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
11.97AlaAla: 11.97 ± 0.168
1.23AlaCys: 1.23 ± 0.034
5.519AlaAsp: 5.519 ± 0.079
6.559AlaGlu: 6.559 ± 0.117
3.409AlaPhe: 3.409 ± 0.062
7.83AlaGly: 7.83 ± 0.123
2.382AlaHis: 2.382 ± 0.06
5.993AlaIle: 5.993 ± 0.082
4.368AlaLys: 4.368 ± 0.087
11.655AlaLeu: 11.655 ± 0.147
3.103AlaMet: 3.103 ± 0.057
3.302AlaAsn: 3.302 ± 0.064
3.527AlaPro: 3.527 ± 0.068
4.913AlaGln: 4.913 ± 0.1
6.227AlaArg: 6.227 ± 0.116
5.822AlaSer: 5.822 ± 0.083
4.95AlaThr: 4.95 ± 0.081
7.216AlaVal: 7.216 ± 0.101
1.241AlaTrp: 1.241 ± 0.036
2.461AlaTyr: 2.461 ± 0.056
0.0AlaXaa: 0.0 ± 0.0
Cys
1.018CysAla: 1.018 ± 0.037
0.137CysCys: 0.137 ± 0.013
0.609CysAsp: 0.609 ± 0.025
0.593CysGlu: 0.593 ± 0.024
0.386CysPhe: 0.386 ± 0.02
1.0CysGly: 1.0 ± 0.033
0.38CysHis: 0.38 ± 0.025
0.576CysIle: 0.576 ± 0.025
0.391CysLys: 0.391 ± 0.019
0.988CysLeu: 0.988 ± 0.038
0.238CysMet: 0.238 ± 0.016
0.408CysAsn: 0.408 ± 0.022
0.528CysPro: 0.528 ± 0.027
0.369CysGln: 0.369 ± 0.023
0.655CysArg: 0.655 ± 0.028
0.656CysSer: 0.656 ± 0.029
0.575CysThr: 0.575 ± 0.025
0.737CysVal: 0.737 ± 0.028
0.137CysTrp: 0.137 ± 0.013
0.318CysTyr: 0.318 ± 0.023
0.0CysXaa: 0.0 ± 0.0
Asp
5.926AspAla: 5.926 ± 0.08
0.552AspCys: 0.552 ± 0.027
2.778AspAsp: 2.778 ± 0.06
3.925AspGlu: 3.925 ± 0.076
2.291AspPhe: 2.291 ± 0.051
3.912AspGly: 3.912 ± 0.074
1.069AspHis: 1.069 ± 0.033
3.356AspIle: 3.356 ± 0.058
2.58AspLys: 2.58 ± 0.053
5.092AspLeu: 5.092 ± 0.074
1.468AspMet: 1.468 ± 0.039
1.778AspAsn: 1.778 ± 0.046
2.115AspPro: 2.115 ± 0.044
1.918AspGln: 1.918 ± 0.042
2.717AspArg: 2.717 ± 0.059
2.849AspSer: 2.849 ± 0.054
2.702AspThr: 2.702 ± 0.061
3.833AspVal: 3.833 ± 0.076
0.867AspTrp: 0.867 ± 0.03
1.733AspTyr: 1.733 ± 0.042
0.0AspXaa: 0.0 ± 0.0
Glu
6.433GluAla: 6.433 ± 0.128
0.509GluCys: 0.509 ± 0.023
2.415GluAsp: 2.415 ± 0.057
3.121GluGlu: 3.121 ± 0.08
2.314GluPhe: 2.314 ± 0.055
3.43GluGly: 3.43 ± 0.064
1.583GluHis: 1.583 ± 0.049
4.007GluIle: 4.007 ± 0.069
3.237GluLys: 3.237 ± 0.067
6.801GluLeu: 6.801 ± 0.094
1.781GluMet: 1.781 ± 0.046
2.171GluAsn: 2.171 ± 0.047
1.802GluPro: 1.802 ± 0.051
3.293GluGln: 3.293 ± 0.116
3.871GluArg: 3.871 ± 0.07
3.382GluSer: 3.382 ± 0.055
2.859GluThr: 2.859 ± 0.053
4.253GluVal: 4.253 ± 0.078
0.77GluTrp: 0.77 ± 0.03
1.513GluTyr: 1.513 ± 0.042
0.0GluXaa: 0.0 ± 0.0
Phe
3.882PheAla: 3.882 ± 0.069
0.44PheCys: 0.44 ± 0.019
2.597PheAsp: 2.597 ± 0.052
2.308PheGlu: 2.308 ± 0.051
1.576PhePhe: 1.576 ± 0.048
3.082PheGly: 3.082 ± 0.06
0.8PheHis: 0.8 ± 0.031
2.201PheIle: 2.201 ± 0.055
1.628PheLys: 1.628 ± 0.042
3.367PheLeu: 3.367 ± 0.068
0.924PheMet: 0.924 ± 0.031
1.496PheAsn: 1.496 ± 0.037
1.475PhePro: 1.475 ± 0.043
1.106PheGln: 1.106 ± 0.033
1.823PheArg: 1.823 ± 0.045
2.83PheSer: 2.83 ± 0.054
1.909PheThr: 1.909 ± 0.051
2.717PheVal: 2.717 ± 0.063
0.446PheTrp: 0.446 ± 0.022
1.12PheTyr: 1.12 ± 0.033
0.0PheXaa: 0.0 ± 0.0
Gly
6.267GlyAla: 6.267 ± 0.115
0.978GlyCys: 0.978 ± 0.035
3.647GlyAsp: 3.647 ± 0.073
4.458GlyGlu: 4.458 ± 0.066
3.021GlyPhe: 3.021 ± 0.057
5.163GlyGly: 5.163 ± 0.101
1.786GlyHis: 1.786 ± 0.042
4.7GlyIle: 4.7 ± 0.076
3.863GlyLys: 3.863 ± 0.078
7.324GlyLeu: 7.324 ± 0.1
2.53GlyMet: 2.53 ± 0.058
2.575GlyAsn: 2.575 ± 0.077
1.513GlyPro: 1.513 ± 0.041
2.665GlyGln: 2.665 ± 0.046
4.308GlyArg: 4.308 ± 0.071
4.148GlySer: 4.148 ± 0.068
3.476GlyThr: 3.476 ± 0.076
5.654GlyVal: 5.654 ± 0.088
1.063GlyTrp: 1.063 ± 0.036
2.389GlyTyr: 2.389 ± 0.053
0.0GlyXaa: 0.0 ± 0.0
His
2.45HisAla: 2.45 ± 0.057
0.32HisCys: 0.32 ± 0.018
1.385HisAsp: 1.385 ± 0.043
1.361HisGlu: 1.361 ± 0.039
1.025HisPhe: 1.025 ± 0.033
1.89HisGly: 1.89 ± 0.052
0.796HisHis: 0.796 ± 0.036
1.363HisIle: 1.363 ± 0.038
0.863HisLys: 0.863 ± 0.032
2.491HisLeu: 2.491 ± 0.054
0.483HisMet: 0.483 ± 0.021
0.768HisAsn: 0.768 ± 0.03
1.441HisPro: 1.441 ± 0.044
1.01HisGln: 1.01 ± 0.034
1.339HisArg: 1.339 ± 0.04
1.291HisSer: 1.291 ± 0.039
1.163HisThr: 1.163 ± 0.032
1.379HisVal: 1.379 ± 0.046
0.333HisTrp: 0.333 ± 0.019
0.828HisTyr: 0.828 ± 0.026
0.0HisXaa: 0.0 ± 0.0
Ile
6.869IleAla: 6.869 ± 0.085
0.622IleCys: 0.622 ± 0.028
3.409IleAsp: 3.409 ± 0.059
4.143IleGlu: 4.143 ± 0.071
1.962IlePhe: 1.962 ± 0.05
4.471IleGly: 4.471 ± 0.085
1.239IleHis: 1.239 ± 0.036
2.892IleIle: 2.892 ± 0.068
2.879IleLys: 2.879 ± 0.061
5.107IleLeu: 5.107 ± 0.091
1.165IleMet: 1.165 ± 0.038
2.419IleAsn: 2.419 ± 0.063
2.584IlePro: 2.584 ± 0.058
1.93IleGln: 1.93 ± 0.053
3.242IleArg: 3.242 ± 0.062
4.161IleSer: 4.161 ± 0.071
3.217IleThr: 3.217 ± 0.063
4.009IleVal: 4.009 ± 0.076
0.6IleTrp: 0.6 ± 0.024
1.378IleTyr: 1.378 ± 0.038
0.0IleXaa: 0.0 ± 0.0
Lys
3.889LysAla: 3.889 ± 0.082
0.315LysCys: 0.315 ± 0.017
1.993LysAsp: 1.993 ± 0.048
2.25LysGlu: 2.25 ± 0.055
1.437LysPhe: 1.437 ± 0.035
2.56LysGly: 2.56 ± 0.049
1.059LysHis: 1.059 ± 0.032
3.053LysIle: 3.053 ± 0.064
2.349LysLys: 2.349 ± 0.056
5.341LysLeu: 5.341 ± 0.088
1.407LysMet: 1.407 ± 0.039
1.99LysAsn: 1.99 ± 0.051
2.322LysPro: 2.322 ± 0.056
2.09LysGln: 2.09 ± 0.051
2.611LysArg: 2.611 ± 0.051
2.87LysSer: 2.87 ± 0.059
2.586LysThr: 2.586 ± 0.054
2.849LysVal: 2.849 ± 0.062
0.491LysTrp: 0.491 ± 0.023
1.081LysTyr: 1.081 ± 0.036
0.0LysXaa: 0.0 ± 0.0
Leu
11.77LeuAla: 11.77 ± 0.139
1.135LeuCys: 1.135 ± 0.036
5.873LeuAsp: 5.873 ± 0.088
5.656LeuGlu: 5.656 ± 0.09
4.107LeuPhe: 4.107 ± 0.077
7.342LeuGly: 7.342 ± 0.106
2.638LeuHis: 2.638 ± 0.056
6.038LeuIle: 6.038 ± 0.097
4.911LeuLys: 4.911 ± 0.076
12.247LeuLeu: 12.247 ± 0.173
2.794LeuMet: 2.794 ± 0.054
4.143LeuAsn: 4.143 ± 0.075
5.389LeuPro: 5.389 ± 0.084
4.392LeuGln: 4.392 ± 0.079
6.534LeuArg: 6.534 ± 0.102
7.728LeuSer: 7.728 ± 0.108
5.94LeuThr: 5.94 ± 0.086
6.749LeuVal: 6.749 ± 0.106
1.171LeuTrp: 1.171 ± 0.041
2.462LeuTyr: 2.462 ± 0.054
0.0LeuXaa: 0.0 ± 0.0
Met
2.654MetAla: 2.654 ± 0.056
0.19MetCys: 0.19 ± 0.014
1.298MetAsp: 1.298 ± 0.034
1.354MetGlu: 1.354 ± 0.043
0.79MetPhe: 0.79 ± 0.033
1.815MetGly: 1.815 ± 0.05
0.672MetHis: 0.672 ± 0.028
1.372MetIle: 1.372 ± 0.042
1.416MetLys: 1.416 ± 0.039
3.177MetLeu: 3.177 ± 0.067
0.726MetMet: 0.726 ± 0.032
1.174MetAsn: 1.174 ± 0.035
1.392MetPro: 1.392 ± 0.041
1.393MetGln: 1.393 ± 0.048
1.812MetArg: 1.812 ± 0.053
1.942MetSer: 1.942 ± 0.035
1.611MetThr: 1.611 ± 0.045
1.772MetVal: 1.772 ± 0.046
0.206MetTrp: 0.206 ± 0.014
0.514MetTyr: 0.514 ± 0.022
0.0MetXaa: 0.0 ± 0.0
Asn
3.491AsnAla: 3.491 ± 0.067
0.435AsnCys: 0.435 ± 0.024
1.908AsnAsp: 1.908 ± 0.052
1.987AsnGlu: 1.987 ± 0.048
1.409AsnPhe: 1.409 ± 0.038
2.732AsnGly: 2.732 ± 0.061
0.806AsnHis: 0.806 ± 0.025
2.096AsnIle: 2.096 ± 0.047
1.588AsnLys: 1.588 ± 0.046
4.023AsnLeu: 4.023 ± 0.072
0.909AsnMet: 0.909 ± 0.033
1.307AsnAsn: 1.307 ± 0.047
2.054AsnPro: 2.054 ± 0.05
1.454AsnGln: 1.454 ± 0.038
2.096AsnArg: 2.096 ± 0.048
1.982AsnSer: 1.982 ± 0.044
1.841AsnThr: 1.841 ± 0.049
2.234AsnVal: 2.234 ± 0.049
0.523AsnTrp: 0.523 ± 0.025
1.048AsnTyr: 1.048 ± 0.036
0.0AsnXaa: 0.0 ± 0.0
Pro
4.449ProAla: 4.449 ± 0.076
0.435ProCys: 0.435 ± 0.029
2.988ProAsp: 2.988 ± 0.061
3.137ProGlu: 3.137 ± 0.061
1.601ProPhe: 1.601 ± 0.042
2.843ProGly: 2.843 ± 0.055
0.969ProHis: 0.969 ± 0.036
1.974ProIle: 1.974 ± 0.047
1.656ProLys: 1.656 ± 0.046
4.373ProLeu: 4.373 ± 0.077
1.031ProMet: 1.031 ± 0.036
1.343ProAsn: 1.343 ± 0.037
1.648ProPro: 1.648 ± 0.04
1.586ProGln: 1.586 ± 0.044
1.818ProArg: 1.818 ± 0.053
2.162ProSer: 2.162 ± 0.048
1.764ProThr: 1.764 ± 0.044
3.921ProVal: 3.921 ± 0.077
0.519ProTrp: 0.519 ± 0.025
1.206ProTyr: 1.206 ± 0.033
0.0ProXaa: 0.0 ± 0.0
Gln
4.719GlnAla: 4.719 ± 0.094
0.359GlnCys: 0.359 ± 0.019
1.961GlnAsp: 1.961 ± 0.048
2.076GlnGlu: 2.076 ± 0.067
1.546GlnPhe: 1.546 ± 0.042
2.857GlnGly: 2.857 ± 0.057
1.157GlnHis: 1.157 ± 0.037
2.517GlnIle: 2.517 ± 0.057
1.742GlnLys: 1.742 ± 0.048
4.885GlnLeu: 4.885 ± 0.088
1.177GlnMet: 1.177 ± 0.032
1.441GlnAsn: 1.441 ± 0.043
1.744GlnPro: 1.744 ± 0.044
2.446GlnGln: 2.446 ± 0.091
2.864GlnArg: 2.864 ± 0.069
2.555GlnSer: 2.555 ± 0.06
2.099GlnThr: 2.099 ± 0.054
2.99GlnVal: 2.99 ± 0.076
0.484GlnTrp: 0.484 ± 0.023
1.056GlnTyr: 1.056 ± 0.034
0.0GlnXaa: 0.0 ± 0.0
Arg
5.602ArgAla: 5.602 ± 0.103
0.591ArgCys: 0.591 ± 0.026
3.301ArgAsp: 3.301 ± 0.07
4.036ArgGlu: 4.036 ± 0.082
2.44ArgPhe: 2.44 ± 0.054
3.573ArgGly: 3.573 ± 0.066
1.551ArgHis: 1.551 ± 0.044
3.883ArgIle: 3.883 ± 0.061
2.374ArgLys: 2.374 ± 0.058
6.669ArgLeu: 6.669 ± 0.087
1.736ArgMet: 1.736 ± 0.046
2.136ArgAsn: 2.136 ± 0.043
2.056ArgPro: 2.056 ± 0.044
2.602ArgGln: 2.602 ± 0.063
3.641ArgArg: 3.641 ± 0.073
3.058ArgSer: 3.058 ± 0.067
2.628ArgThr: 2.628 ± 0.047
4.2ArgVal: 4.2 ± 0.058
0.756ArgTrp: 0.756 ± 0.028
1.937ArgTyr: 1.937 ± 0.051
0.0ArgXaa: 0.0 ± 0.0
Ser
6.173SerAla: 6.173 ± 0.078
0.668SerCys: 0.668 ± 0.029
3.338SerAsp: 3.338 ± 0.061
3.624SerGlu: 3.624 ± 0.067
2.276SerPhe: 2.276 ± 0.045
5.572SerGly: 5.572 ± 0.085
1.392SerHis: 1.392 ± 0.036
3.408SerIle: 3.408 ± 0.073
2.42SerLys: 2.42 ± 0.049
6.359SerLeu: 6.359 ± 0.093
1.619SerMet: 1.619 ± 0.044
2.145SerAsn: 2.145 ± 0.053
2.376SerPro: 2.376 ± 0.053
2.35SerGln: 2.35 ± 0.053
3.535SerArg: 3.535 ± 0.066
3.76SerSer: 3.76 ± 0.074
3.075SerThr: 3.075 ± 0.064
4.48SerVal: 4.48 ± 0.067
0.742SerTrp: 0.742 ± 0.029
1.615SerTyr: 1.615 ± 0.049
0.0SerXaa: 0.0 ± 0.0
Thr
5.009ThrAla: 5.009 ± 0.084
0.485ThrCys: 0.485 ± 0.025
2.785ThrAsp: 2.785 ± 0.052
2.822ThrGlu: 2.822 ± 0.055
1.774ThrPhe: 1.774 ± 0.041
4.335ThrGly: 4.335 ± 0.073
1.321ThrHis: 1.321 ± 0.044
2.658ThrIle: 2.658 ± 0.065
1.603ThrLys: 1.603 ± 0.043
6.448ThrLeu: 6.448 ± 0.105
1.116ThrMet: 1.116 ± 0.034
1.501ThrAsn: 1.501 ± 0.045
2.894ThrPro: 2.894 ± 0.056
2.194ThrGln: 2.194 ± 0.052
2.883ThrArg: 2.883 ± 0.053
2.777ThrSer: 2.777 ± 0.064
2.602ThrThr: 2.602 ± 0.064
3.774ThrVal: 3.774 ± 0.071
0.489ThrTrp: 0.489 ± 0.024
1.228ThrTyr: 1.228 ± 0.039
0.0ThrXaa: 0.0 ± 0.0
Val
7.503ValAla: 7.503 ± 0.102
0.775ValCys: 0.775 ± 0.03
3.726ValAsp: 3.726 ± 0.072
4.318ValGlu: 4.318 ± 0.078
2.657ValPhe: 2.657 ± 0.05
4.493ValGly: 4.493 ± 0.081
1.368ValHis: 1.368 ± 0.039
4.303ValIle: 4.303 ± 0.072
3.176ValLys: 3.176 ± 0.065
7.73ValLeu: 7.73 ± 0.101
2.168ValMet: 2.168 ± 0.048
2.559ValAsn: 2.559 ± 0.055
2.849ValPro: 2.849 ± 0.058
2.76ValGln: 2.76 ± 0.064
4.026ValArg: 4.026 ± 0.067
4.626ValSer: 4.626 ± 0.081
3.854ValThr: 3.854 ± 0.07
5.579ValVal: 5.579 ± 0.091
0.86ValTrp: 0.86 ± 0.033
1.63ValTyr: 1.63 ± 0.041
0.0ValXaa: 0.0 ± 0.0
Trp
0.909TrpAla: 0.909 ± 0.03
0.16TrpCys: 0.16 ± 0.013
0.627TrpAsp: 0.627 ± 0.025
0.571TrpGlu: 0.571 ± 0.025
0.522TrpPhe: 0.522 ± 0.024
0.676TrpGly: 0.676 ± 0.029
0.362TrpHis: 0.362 ± 0.022
0.654TrpIle: 0.654 ± 0.028
0.488TrpLys: 0.488 ± 0.026
1.764TrpLeu: 1.764 ± 0.053
0.382TrpMet: 0.382 ± 0.02
0.432TrpAsn: 0.432 ± 0.02
0.421TrpPro: 0.421 ± 0.021
0.835TrpGln: 0.835 ± 0.034
0.914TrpArg: 0.914 ± 0.035
0.669TrpSer: 0.669 ± 0.026
0.488TrpThr: 0.488 ± 0.024
0.926TrpVal: 0.926 ± 0.036
0.194TrpTrp: 0.194 ± 0.016
0.29TrpTyr: 0.29 ± 0.021
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.696TyrAla: 2.696 ± 0.059
0.366TyrCys: 0.366 ± 0.02
1.305TyrAsp: 1.305 ± 0.038
1.245TyrGlu: 1.245 ± 0.038
1.182TyrPhe: 1.182 ± 0.039
1.95TyrGly: 1.95 ± 0.048
0.648TyrHis: 0.648 ± 0.029
1.255TyrIle: 1.255 ± 0.04
1.01TyrLys: 1.01 ± 0.035
3.176TyrLeu: 3.176 ± 0.059
0.524TyrMet: 0.524 ± 0.025
0.836TyrAsn: 0.836 ± 0.034
1.292TyrPro: 1.292 ± 0.037
1.369TyrGln: 1.369 ± 0.034
1.852TyrArg: 1.852 ± 0.045
1.66TyrSer: 1.66 ± 0.044
1.359TyrThr: 1.359 ± 0.041
1.687TyrVal: 1.687 ± 0.048
0.392TyrTrp: 0.392 ± 0.021
0.778TyrTyr: 0.778 ± 0.035
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2853 proteins (938798 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski