Amino acid dipepetide frequency for Tessaracoccus flavescens

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	16.717AlaAla: 16.717 ± 0.197	0.974AlaCys: 0.974 ± 0.033	7.794AlaAsp: 7.794 ± 0.087	8.33AlaGlu: 8.33 ± 0.114	3.5AlaPhe: 3.5 ± 0.057	10.426AlaGly: 10.426 ± 0.124	2.26AlaHis: 2.26 ± 0.048	5.245AlaIle: 5.245 ± 0.076	3.345AlaLys: 3.345 ± 0.066	12.644AlaLeu: 12.644 ± 0.148	2.998AlaMet: 2.998 ± 0.053	2.431AlaAsn: 2.431 ± 0.055	5.523AlaPro: 5.523 ± 0.09	3.9AlaGln: 3.9 ± 0.063	8.341AlaArg: 8.341 ± 0.108	6.855AlaSer: 6.855 ± 0.099	7.092AlaThr: 7.092 ± 0.095	10.178AlaVal: 10.178 ± 0.12	2.05AlaTrp: 2.05 ± 0.047	2.39AlaTyr: 2.39 ± 0.048	0.0AlaXaa: 0.0 ± 0.0
Cys	0.798CysAla: 0.798 ± 0.028	0.088CysCys: 0.088 ± 0.01	0.444CysAsp: 0.444 ± 0.02	0.374CysGlu: 0.374 ± 0.02	0.205CysPhe: 0.205 ± 0.015	0.802CysGly: 0.802 ± 0.027	0.172CysHis: 0.172 ± 0.012	0.244CysIle: 0.244 ± 0.015	0.097CysLys: 0.097 ± 0.009	0.638CysLeu: 0.638 ± 0.025	0.127CysMet: 0.127 ± 0.011	0.135CysAsn: 0.135 ± 0.012	0.482CysPro: 0.482 ± 0.023	0.191CysGln: 0.191 ± 0.013	0.565CysArg: 0.565 ± 0.028	0.451CysSer: 0.451 ± 0.022	0.434CysThr: 0.434 ± 0.022	0.537CysVal: 0.537 ± 0.023	0.111CysTrp: 0.111 ± 0.011	0.167CysTyr: 0.167 ± 0.013	0.0CysXaa: 0.0 ± 0.0
Asp	7.618AspAla: 7.618 ± 0.082	0.35AspCys: 0.35 ± 0.024	4.309AspAsp: 4.309 ± 0.085	4.898AspGlu: 4.898 ± 0.078	1.825AspPhe: 1.825 ± 0.044	5.993AspGly: 5.993 ± 0.087	1.338AspHis: 1.338 ± 0.041	2.285AspIle: 2.285 ± 0.049	1.475AspLys: 1.475 ± 0.042	6.98AspLeu: 6.98 ± 0.093	0.945AspMet: 0.945 ± 0.03	1.16AspAsn: 1.16 ± 0.038	4.432AspPro: 4.432 ± 0.08	2.033AspGln: 2.033 ± 0.044	4.216AspArg: 4.216 ± 0.068	2.791AspSer: 2.791 ± 0.057	2.815AspThr: 2.815 ± 0.054	5.076AspVal: 5.076 ± 0.076	1.003AspTrp: 1.003 ± 0.034	1.297AspTyr: 1.297 ± 0.034	0.0AspXaa: 0.0 ± 0.0
Glu	8.111GluAla: 8.111 ± 0.122	0.365GluCys: 0.365 ± 0.019	3.071GluAsp: 3.071 ± 0.056	3.556GluGlu: 3.556 ± 0.077	1.814GluPhe: 1.814 ± 0.047	4.758GluGly: 4.758 ± 0.069	1.422GluHis: 1.422 ± 0.04	2.777GluIle: 2.777 ± 0.061	1.62GluLys: 1.62 ± 0.048	7.005GluLeu: 7.005 ± 0.091	1.039GluMet: 1.039 ± 0.036	1.173GluAsn: 1.173 ± 0.036	3.311GluPro: 3.311 ± 0.069	2.469GluGln: 2.469 ± 0.057	5.228GluArg: 5.228 ± 0.082	2.966GluSer: 2.966 ± 0.065	3.159GluThr: 3.159 ± 0.059	5.302GluVal: 5.302 ± 0.075	0.8GluTrp: 0.8 ± 0.033	1.07GluTyr: 1.07 ± 0.035	0.0GluXaa: 0.0 ± 0.0
Phe	3.709PheAla: 3.709 ± 0.063	0.248PheCys: 0.248 ± 0.017	2.437PheAsp: 2.437 ± 0.059	1.792PheGlu: 1.792 ± 0.045	1.014PhePhe: 1.014 ± 0.039	3.071PheGly: 3.071 ± 0.063	0.608PheHis: 0.608 ± 0.026	1.194PheIle: 1.194 ± 0.043	0.635PheLys: 0.635 ± 0.028	2.739PheLeu: 2.739 ± 0.062	0.525PheMet: 0.525 ± 0.028	0.805PheAsn: 0.805 ± 0.034	1.422PhePro: 1.422 ± 0.037	0.772PheGln: 0.772 ± 0.026	1.706PheArg: 1.706 ± 0.036	1.727PheSer: 1.727 ± 0.041	2.061PheThr: 2.061 ± 0.047	2.621PheVal: 2.621 ± 0.051	0.432PheTrp: 0.432 ± 0.023	0.593PheTyr: 0.593 ± 0.025	0.0PheXaa: 0.0 ± 0.0
Gly	9.132GlyAla: 9.132 ± 0.111	0.739GlyCys: 0.739 ± 0.032	5.136GlyAsp: 5.136 ± 0.08	5.152GlyGlu: 5.152 ± 0.07	3.16GlyPhe: 3.16 ± 0.056	7.218GlyGly: 7.218 ± 0.126	1.888GlyHis: 1.888 ± 0.05	4.104GlyIle: 4.104 ± 0.07	2.482GlyLys: 2.482 ± 0.066	8.886GlyLeu: 8.886 ± 0.109	2.134GlyMet: 2.134 ± 0.047	1.876GlyAsn: 1.876 ± 0.048	3.754GlyPro: 3.754 ± 0.072	2.872GlyGln: 2.872 ± 0.062	6.705GlyArg: 6.705 ± 0.096	5.211GlySer: 5.211 ± 0.081	5.244GlyThr: 5.244 ± 0.091	7.557GlyVal: 7.557 ± 0.096	1.846GlyTrp: 1.846 ± 0.045	2.251GlyTyr: 2.251 ± 0.05	0.0GlyXaa: 0.0 ± 0.0
His	2.209HisAla: 2.209 ± 0.045	0.162HisCys: 0.162 ± 0.014	1.369HisAsp: 1.369 ± 0.042	1.194HisGlu: 1.194 ± 0.038	0.591HisPhe: 0.591 ± 0.023	1.877HisGly: 1.877 ± 0.046	0.574HisHis: 0.574 ± 0.027	0.747HisIle: 0.747 ± 0.03	0.4HisLys: 0.4 ± 0.022	2.186HisLeu: 2.186 ± 0.047	0.316HisMet: 0.316 ± 0.017	0.412HisAsn: 0.412 ± 0.018	1.397HisPro: 1.397 ± 0.039	0.595HisGln: 0.595 ± 0.026	1.738HisArg: 1.738 ± 0.045	0.974HisSer: 0.974 ± 0.033	1.11HisThr: 1.11 ± 0.031	1.651HisVal: 1.651 ± 0.042	0.317HisTrp: 0.317 ± 0.016	0.44HisTyr: 0.44 ± 0.024	0.0HisXaa: 0.0 ± 0.0
Ile	6.083IleAla: 6.083 ± 0.081	0.333IleCys: 0.333 ± 0.019	3.382IleAsp: 3.382 ± 0.052	2.912IleGlu: 2.912 ± 0.056	1.183IlePhe: 1.183 ± 0.035	4.276IleGly: 4.276 ± 0.073	0.76IleHis: 0.76 ± 0.028	1.729IleIle: 1.729 ± 0.051	0.924IleLys: 0.924 ± 0.036	3.499IleLeu: 3.499 ± 0.076	0.71IleMet: 0.71 ± 0.03	1.079IleAsn: 1.079 ± 0.033	2.142IlePro: 2.142 ± 0.049	1.065IleGln: 1.065 ± 0.039	2.632IleArg: 2.632 ± 0.051	2.501IleSer: 2.501 ± 0.048	2.699IleThr: 2.699 ± 0.06	4.132IleVal: 4.132 ± 0.07	0.539IleTrp: 0.539 ± 0.024	0.809IleTyr: 0.809 ± 0.033	0.0IleXaa: 0.0 ± 0.0
Lys	3.434LysAla: 3.434 ± 0.066	0.107LysCys: 0.107 ± 0.01	1.274LysAsp: 1.274 ± 0.04	1.279LysGlu: 1.279 ± 0.041	0.63LysPhe: 0.63 ± 0.026	2.119LysGly: 2.119 ± 0.054	0.463LysHis: 0.463 ± 0.02	1.039LysIle: 1.039 ± 0.037	0.964LysLys: 0.964 ± 0.035	2.471LysLeu: 2.471 ± 0.06	0.481LysMet: 0.481 ± 0.021	0.57LysAsn: 0.57 ± 0.027	1.356LysPro: 1.356 ± 0.035	0.851LysGln: 0.851 ± 0.032	1.717LysArg: 1.717 ± 0.047	1.337LysSer: 1.337 ± 0.037	1.527LysThr: 1.527 ± 0.043	2.347LysVal: 2.347 ± 0.056	0.343LysTrp: 0.343 ± 0.019	0.522LysTyr: 0.522 ± 0.024	0.0LysXaa: 0.0 ± 0.0
Leu	13.534LeuAla: 13.534 ± 0.156	0.615LeuCys: 0.615 ± 0.025	6.837LeuAsp: 6.837 ± 0.091	5.497LeuGlu: 5.497 ± 0.083	2.693LeuPhe: 2.693 ± 0.056	9.256LeuGly: 9.256 ± 0.11	1.919LeuHis: 1.919 ± 0.042	4.671LeuIle: 4.671 ± 0.08	2.271LeuLys: 2.271 ± 0.056	10.194LeuLeu: 10.194 ± 0.14	1.887LeuMet: 1.887 ± 0.044	2.134LeuAsn: 2.134 ± 0.048	5.515LeuPro: 5.515 ± 0.071	2.556LeuGln: 2.556 ± 0.048	7.76LeuArg: 7.76 ± 0.115	5.966LeuSer: 5.966 ± 0.092	6.675LeuThr: 6.675 ± 0.08	8.749LeuVal: 8.749 ± 0.119	1.233LeuTrp: 1.233 ± 0.038	1.55LeuTyr: 1.55 ± 0.037	0.0LeuXaa: 0.0 ± 0.0
Met	2.559MetAla: 2.559 ± 0.057	0.134MetCys: 0.134 ± 0.011	0.987MetAsp: 0.987 ± 0.035	0.873MetGlu: 0.873 ± 0.031	0.601MetPhe: 0.601 ± 0.024	1.596MetGly: 1.596 ± 0.044	0.34MetHis: 0.34 ± 0.018	0.968MetIle: 0.968 ± 0.033	0.532MetLys: 0.532 ± 0.024	2.072MetLeu: 2.072 ± 0.041	0.407MetMet: 0.407 ± 0.02	0.568MetAsn: 0.568 ± 0.022	1.13MetPro: 1.13 ± 0.037	0.586MetGln: 0.586 ± 0.022	1.466MetArg: 1.466 ± 0.033	1.606MetSer: 1.606 ± 0.032	1.626MetThr: 1.626 ± 0.036	1.579MetVal: 1.579 ± 0.043	0.251MetTrp: 0.251 ± 0.018	0.294MetTyr: 0.294 ± 0.017	0.0MetXaa: 0.0 ± 0.0
Asn	2.461AsnAla: 2.461 ± 0.054	0.129AsnCys: 0.129 ± 0.011	1.274AsnAsp: 1.274 ± 0.035	1.128AsnGlu: 1.128 ± 0.03	0.645AsnPhe: 0.645 ± 0.025	1.965AsnGly: 1.965 ± 0.048	0.478AsnHis: 0.478 ± 0.021	0.874AsnIle: 0.874 ± 0.034	0.475AsnLys: 0.475 ± 0.025	2.271AsnLeu: 2.271 ± 0.051	0.408AsnMet: 0.408 ± 0.021	0.607AsnAsn: 0.607 ± 0.027	1.716AsnPro: 1.716 ± 0.045	0.759AsnGln: 0.759 ± 0.027	1.532AsnArg: 1.532 ± 0.039	1.16AsnSer: 1.16 ± 0.037	1.19AsnThr: 1.19 ± 0.04	1.711AsnVal: 1.711 ± 0.046	0.355AsnTrp: 0.355 ± 0.019	0.567AsnTyr: 0.567 ± 0.023	0.0AsnXaa: 0.0 ± 0.0
Pro	6.434ProAla: 6.434 ± 0.089	0.279ProCys: 0.279 ± 0.017	3.963ProAsp: 3.963 ± 0.066	4.201ProGlu: 4.201 ± 0.07	1.466ProPhe: 1.466 ± 0.044	5.218ProGly: 5.218 ± 0.078	1.067ProHis: 1.067 ± 0.036	1.987ProIle: 1.987 ± 0.045	1.365ProLys: 1.365 ± 0.043	4.562ProLeu: 4.562 ± 0.071	1.079ProMet: 1.079 ± 0.031	1.138ProAsn: 1.138 ± 0.034	2.432ProPro: 2.432 ± 0.059	1.674ProGln: 1.674 ± 0.042	3.321ProArg: 3.321 ± 0.064	3.409ProSer: 3.409 ± 0.069	3.824ProThr: 3.824 ± 0.078	4.584ProVal: 4.584 ± 0.071	0.828ProTrp: 0.828 ± 0.03	1.041ProTyr: 1.041 ± 0.033	0.0ProXaa: 0.0 ± 0.0
Gln	3.952GlnAla: 3.952 ± 0.077	0.169GlnCys: 0.169 ± 0.011	1.378GlnAsp: 1.378 ± 0.043	1.551GlnGlu: 1.551 ± 0.044	0.972GlnPhe: 0.972 ± 0.032	2.279GlnGly: 2.279 ± 0.051	0.699GlnHis: 0.699 ± 0.028	1.496GlnIle: 1.496 ± 0.041	0.737GlnLys: 0.737 ± 0.029	3.536GlnLeu: 3.536 ± 0.06	0.584GlnMet: 0.584 ± 0.022	0.614GlnAsn: 0.614 ± 0.026	1.884GlnPro: 1.884 ± 0.052	1.372GlnGln: 1.372 ± 0.05	2.695GlnArg: 2.695 ± 0.047	1.491GlnSer: 1.491 ± 0.037	1.554GlnThr: 1.554 ± 0.04	2.772GlnVal: 2.772 ± 0.057	0.547GlnTrp: 0.547 ± 0.025	0.623GlnTyr: 0.623 ± 0.028	0.0GlnXaa: 0.0 ± 0.0
Arg	7.847ArgAla: 7.847 ± 0.103	0.566ArgCys: 0.566 ± 0.027	4.389ArgAsp: 4.389 ± 0.069	4.457ArgGlu: 4.457 ± 0.075	2.406ArgPhe: 2.406 ± 0.052	5.388ArgGly: 5.388 ± 0.079	1.702ArgHis: 1.702 ± 0.044	3.597ArgIle: 3.597 ± 0.065	1.737ArgLys: 1.737 ± 0.047	7.703ArgLeu: 7.703 ± 0.11	1.654ArgMet: 1.654 ± 0.042	1.591ArgAsn: 1.591 ± 0.042	3.927ArgPro: 3.927 ± 0.07	2.452ArgGln: 2.452 ± 0.047	6.839ArgArg: 6.839 ± 0.114	4.173ArgSer: 4.173 ± 0.074	3.989ArgThr: 3.989 ± 0.072	5.648ArgVal: 5.648 ± 0.086	1.314ArgTrp: 1.314 ± 0.036	1.684ArgTyr: 1.684 ± 0.045	0.0ArgXaa: 0.0 ± 0.0
Ser	6.507SerAla: 6.507 ± 0.085	0.397SerCys: 0.397 ± 0.021	3.286SerAsp: 3.286 ± 0.059	3.148SerGlu: 3.148 ± 0.056	1.794SerPhe: 1.794 ± 0.044	5.528SerGly: 5.528 ± 0.083	1.073SerHis: 1.073 ± 0.037	2.474SerIle: 2.474 ± 0.051	1.424SerLys: 1.424 ± 0.037	5.53SerLeu: 5.53 ± 0.082	1.423SerMet: 1.423 ± 0.035	1.263SerAsn: 1.263 ± 0.032	3.142SerPro: 3.142 ± 0.062	1.702SerGln: 1.702 ± 0.042	3.979SerArg: 3.979 ± 0.071	3.478SerSer: 3.478 ± 0.07	3.545SerThr: 3.545 ± 0.074	4.767SerVal: 4.767 ± 0.068	0.961SerTrp: 0.961 ± 0.034	1.337SerTyr: 1.337 ± 0.037	0.0SerXaa: 0.0 ± 0.0
Thr	6.98ThrAla: 6.98 ± 0.101	0.492ThrCys: 0.492 ± 0.023	3.471ThrAsp: 3.471 ± 0.062	3.097ThrGlu: 3.097 ± 0.068	1.832ThrPhe: 1.832 ± 0.039	5.6ThrGly: 5.6 ± 0.084	1.135ThrHis: 1.135 ± 0.031	2.607ThrIle: 2.607 ± 0.054	1.515ThrLys: 1.515 ± 0.046	5.844ThrLeu: 5.844 ± 0.071	1.206ThrMet: 1.206 ± 0.039	1.308ThrAsn: 1.308 ± 0.048	4.018ThrPro: 4.018 ± 0.079	1.775ThrGln: 1.775 ± 0.042	3.992ThrArg: 3.992 ± 0.07	3.567ThrSer: 3.567 ± 0.07	4.023ThrThr: 4.023 ± 0.101	5.537ThrVal: 5.537 ± 0.074	1.056ThrTrp: 1.056 ± 0.041	1.334ThrTyr: 1.334 ± 0.038	0.0ThrXaa: 0.0 ± 0.0
Val	10.873ValAla: 10.873 ± 0.112	0.628ValCys: 0.628 ± 0.025	5.923ValAsp: 5.923 ± 0.078	5.608ValGlu: 5.608 ± 0.083	2.489ValPhe: 2.489 ± 0.056	7.099ValGly: 7.099 ± 0.089	1.617ValHis: 1.617 ± 0.046	4.012ValIle: 4.012 ± 0.069	1.941ValLys: 1.941 ± 0.048	8.529ValLeu: 8.529 ± 0.106	1.648ValMet: 1.648 ± 0.04	1.929ValAsn: 1.929 ± 0.052	4.41ValPro: 4.41 ± 0.066	2.027ValGln: 2.027 ± 0.042	5.567ValArg: 5.567 ± 0.074	4.916ValSer: 4.916 ± 0.068	5.752ValThr: 5.752 ± 0.078	8.191ValVal: 8.191 ± 0.108	1.2ValTrp: 1.2 ± 0.035	1.404ValTyr: 1.404 ± 0.036	0.0ValXaa: 0.0 ± 0.0
Trp	1.711TrpAla: 1.711 ± 0.042	0.121TrpCys: 0.121 ± 0.01	0.796TrpAsp: 0.796 ± 0.03	0.751TrpGlu: 0.751 ± 0.027	0.594TrpPhe: 0.594 ± 0.021	1.119TrpGly: 1.119 ± 0.037	0.335TrpHis: 0.335 ± 0.019	0.686TrpIle: 0.686 ± 0.032	0.428TrpLys: 0.428 ± 0.02	1.925TrpLeu: 1.925 ± 0.046	0.332TrpMet: 0.332 ± 0.017	0.42TrpAsn: 0.42 ± 0.02	0.814TrpPro: 0.814 ± 0.029	0.617TrpGln: 0.617 ± 0.023	1.393TrpArg: 1.393 ± 0.042	1.025TrpSer: 1.025 ± 0.029	0.909TrpThr: 0.909 ± 0.031	1.221TrpVal: 1.221 ± 0.036	0.369TrpTrp: 0.369 ± 0.021	0.313TrpTyr: 0.313 ± 0.02	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.323TyrAla: 2.323 ± 0.047	0.165TyrCys: 0.165 ± 0.012	1.318TyrAsp: 1.318 ± 0.04	1.22TyrGlu: 1.22 ± 0.039	0.695TyrPhe: 0.695 ± 0.029	1.755TyrGly: 1.755 ± 0.042	0.408TyrHis: 0.408 ± 0.022	0.652TyrIle: 0.652 ± 0.028	0.465TyrLys: 0.465 ± 0.023	2.298TyrLeu: 2.298 ± 0.048	0.274TyrMet: 0.274 ± 0.017	0.494TyrAsn: 0.494 ± 0.026	1.068TyrPro: 1.068 ± 0.033	0.635TyrGln: 0.635 ± 0.024	1.672TyrArg: 1.672 ± 0.045	1.152TyrSer: 1.152 ± 0.036	1.161TyrThr: 1.161 ± 0.041	1.603TyrVal: 1.603 ± 0.044	0.324TyrTrp: 0.324 ± 0.02	0.45TyrTyr: 0.45 ± 0.023	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3222 proteins (1009990 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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