Amino acid dipepetide frequency for Agrilactobacillus composti DSM 18527 = JCM 14202

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	9.126AlaAla: 9.126 ± 0.134	0.543AlaCys: 0.543 ± 0.028	5.478AlaAsp: 5.478 ± 0.077	4.012AlaGlu: 4.012 ± 0.078	3.69AlaPhe: 3.69 ± 0.06	6.504AlaGly: 6.504 ± 0.098	1.761AlaHis: 1.761 ± 0.044	6.727AlaIle: 6.727 ± 0.096	6.334AlaLys: 6.334 ± 0.085	9.491AlaLeu: 9.491 ± 0.122	2.362AlaMet: 2.362 ± 0.055	4.079AlaAsn: 4.079 ± 0.064	2.956AlaPro: 2.956 ± 0.062	5.163AlaGln: 5.163 ± 0.099	2.776AlaArg: 2.776 ± 0.061	4.623AlaSer: 4.623 ± 0.068	5.877AlaThr: 5.877 ± 0.101	6.412AlaVal: 6.412 ± 0.082	0.804AlaTrp: 0.804 ± 0.029	3.114AlaTyr: 3.114 ± 0.054	0.004AlaXaa: 0.004 ± 0.002
Cys	0.453CysAla: 0.453 ± 0.023	0.055CysCys: 0.055 ± 0.007	0.28CysAsp: 0.28 ± 0.016	0.211CysGlu: 0.211 ± 0.014	0.254CysPhe: 0.254 ± 0.018	0.583CysGly: 0.583 ± 0.026	0.178CysHis: 0.178 ± 0.015	0.279CysIle: 0.279 ± 0.016	0.148CysLys: 0.148 ± 0.012	0.611CysLeu: 0.611 ± 0.028	0.098CysMet: 0.098 ± 0.01	0.2CysAsn: 0.2 ± 0.014	0.295CysPro: 0.295 ± 0.02	0.262CysGln: 0.262 ± 0.017	0.236CysArg: 0.236 ± 0.014	0.298CysSer: 0.298 ± 0.019	0.297CysThr: 0.297 ± 0.018	0.342CysVal: 0.342 ± 0.02	0.061CysTrp: 0.061 ± 0.008	0.203CysTyr: 0.203 ± 0.015	0.0CysXaa: 0.0 ± 0.0
Asp	4.519AspAla: 4.519 ± 0.072	0.269AspCys: 0.269 ± 0.018	3.041AspAsp: 3.041 ± 0.065	2.882AspGlu: 2.882 ± 0.073	2.933AspPhe: 2.933 ± 0.052	3.471AspGly: 3.471 ± 0.065	1.346AspHis: 1.346 ± 0.036	3.709AspIle: 3.709 ± 0.072	3.357AspLys: 3.357 ± 0.066	6.061AspLeu: 6.061 ± 0.091	1.49AspMet: 1.49 ± 0.044	2.491AspAsn: 2.491 ± 0.051	2.757AspPro: 2.757 ± 0.049	3.221AspGln: 3.221 ± 0.063	2.122AspArg: 2.122 ± 0.052	2.669AspSer: 2.669 ± 0.05	3.38AspThr: 3.38 ± 0.061	3.756AspVal: 3.756 ± 0.068	0.702AspTrp: 0.702 ± 0.025	2.497AspTyr: 2.497 ± 0.052	0.0AspXaa: 0.0 ± 0.0
Glu	4.265GluAla: 4.265 ± 0.074	0.175GluCys: 0.175 ± 0.012	2.447GluAsp: 2.447 ± 0.052	1.885GluGlu: 1.885 ± 0.059	1.834GluPhe: 1.834 ± 0.049	2.193GluGly: 2.193 ± 0.053	0.937GluHis: 0.937 ± 0.032	3.404GluIle: 3.404 ± 0.062	3.019GluLys: 3.019 ± 0.065	4.754GluLeu: 4.754 ± 0.076	1.319GluMet: 1.319 ± 0.041	2.341GluAsn: 2.341 ± 0.048	1.677GluPro: 1.677 ± 0.049	2.066GluGln: 2.066 ± 0.054	1.758GluArg: 1.758 ± 0.049	2.1GluSer: 2.1 ± 0.048	2.831GluThr: 2.831 ± 0.064	3.123GluVal: 3.123 ± 0.062	0.376GluTrp: 0.376 ± 0.019	1.284GluTyr: 1.284 ± 0.034	0.001GluXaa: 0.001 ± 0.001
Phe	3.528PheAla: 3.528 ± 0.065	0.289PheCys: 0.289 ± 0.016	2.797PheAsp: 2.797 ± 0.056	2.144PheGlu: 2.144 ± 0.047	1.995PhePhe: 1.995 ± 0.048	3.459PheGly: 3.459 ± 0.067	0.784PheHis: 0.784 ± 0.03	3.063PheIle: 3.063 ± 0.062	2.697PheLys: 2.697 ± 0.054	4.201PheLeu: 4.201 ± 0.077	1.125PheMet: 1.125 ± 0.036	2.189PheAsn: 2.189 ± 0.05	1.546PhePro: 1.546 ± 0.039	1.748PheGln: 1.748 ± 0.044	1.333PheArg: 1.333 ± 0.034	2.755PheSer: 2.755 ± 0.059	2.599PheThr: 2.599 ± 0.053	3.091PheVal: 3.091 ± 0.065	0.548PheTrp: 0.548 ± 0.026	1.668PheTyr: 1.668 ± 0.039	0.001PheXaa: 0.001 ± 0.001
Gly	5.773GlyAla: 5.773 ± 0.084	0.458GlyCys: 0.458 ± 0.022	3.519GlyAsp: 3.519 ± 0.058	2.799GlyGlu: 2.799 ± 0.06	3.392GlyPhe: 3.392 ± 0.063	4.628GlyGly: 4.628 ± 0.095	1.594GlyHis: 1.594 ± 0.043	5.536GlyIle: 5.536 ± 0.095	4.02GlyLys: 4.02 ± 0.071	7.266GlyLeu: 7.266 ± 0.091	1.874GlyMet: 1.874 ± 0.049	2.822GlyAsn: 2.822 ± 0.056	1.988GlyPro: 1.988 ± 0.047	3.597GlyGln: 3.597 ± 0.066	2.527GlyArg: 2.527 ± 0.057	3.894GlySer: 3.894 ± 0.062	4.593GlyThr: 4.593 ± 0.09	4.986GlyVal: 4.986 ± 0.091	0.741GlyTrp: 0.741 ± 0.031	2.803GlyTyr: 2.803 ± 0.06	0.001GlyXaa: 0.001 ± 0.001
His	1.379HisAla: 1.379 ± 0.041	0.162HisCys: 0.162 ± 0.012	1.18HisAsp: 1.18 ± 0.035	1.062HisGlu: 1.062 ± 0.029	1.135HisPhe: 1.135 ± 0.028	1.408HisGly: 1.408 ± 0.037	0.716HisHis: 0.716 ± 0.029	1.475HisIle: 1.475 ± 0.041	1.022HisLys: 1.022 ± 0.03	2.246HisLeu: 2.246 ± 0.051	0.505HisMet: 0.505 ± 0.025	0.949HisAsn: 0.949 ± 0.031	1.022HisPro: 1.022 ± 0.033	1.29HisGln: 1.29 ± 0.045	0.848HisArg: 0.848 ± 0.029	0.999HisSer: 0.999 ± 0.035	1.149HisThr: 1.149 ± 0.034	1.371HisVal: 1.371 ± 0.039	0.319HisTrp: 0.319 ± 0.02	1.002HisTyr: 1.002 ± 0.033	0.002HisXaa: 0.002 ± 0.001
Ile	6.708IleAla: 6.708 ± 0.104	0.495IleCys: 0.495 ± 0.023	4.027IleAsp: 4.027 ± 0.077	3.066IleGlu: 3.066 ± 0.062	3.236IlePhe: 3.236 ± 0.07	5.332IleGly: 5.332 ± 0.094	1.406IleHis: 1.406 ± 0.039	4.822IleIle: 4.822 ± 0.085	3.782IleLys: 3.782 ± 0.062	6.991IleLeu: 6.991 ± 0.112	1.644IleMet: 1.644 ± 0.036	3.268IleAsn: 3.268 ± 0.06	3.15IlePro: 3.15 ± 0.065	3.153IleGln: 3.153 ± 0.062	2.392IleArg: 2.392 ± 0.051	4.364IleSer: 4.364 ± 0.072	4.419IleThr: 4.419 ± 0.067	4.804IleVal: 4.804 ± 0.08	0.648IleTrp: 0.648 ± 0.03	2.334IleTyr: 2.334 ± 0.044	0.002IleXaa: 0.002 ± 0.001
Lys	5.88LysAla: 5.88 ± 0.081	0.169LysCys: 0.169 ± 0.016	3.512LysAsp: 3.512 ± 0.064	2.702LysGlu: 2.702 ± 0.059	1.919LysPhe: 1.919 ± 0.045	3.27LysGly: 3.27 ± 0.05	1.227LysHis: 1.227 ± 0.034	4.183LysIle: 4.183 ± 0.077	3.633LysLys: 3.633 ± 0.071	5.449LysLeu: 5.449 ± 0.079	1.71LysMet: 1.71 ± 0.038	2.838LysAsn: 2.838 ± 0.058	2.36LysPro: 2.36 ± 0.056	3.097LysGln: 3.097 ± 0.057	2.765LysArg: 2.765 ± 0.049	2.962LysSer: 2.962 ± 0.052	4.305LysThr: 4.305 ± 0.072	4.054LysVal: 4.054 ± 0.059	0.5LysTrp: 0.5 ± 0.024	1.954LysTyr: 1.954 ± 0.041	0.0LysXaa: 0.0 ± 0.0
Leu	10.538LeuAla: 10.538 ± 0.109	0.566LeuCys: 0.566 ± 0.026	5.622LeuAsp: 5.622 ± 0.088	4.023LeuGlu: 4.023 ± 0.079	4.3LeuPhe: 4.3 ± 0.08	7.409LeuGly: 7.409 ± 0.096	1.876LeuHis: 1.876 ± 0.041	7.034LeuIle: 7.034 ± 0.111	6.436LeuLys: 6.436 ± 0.085	10.546LeuLeu: 10.546 ± 0.169	2.573LeuMet: 2.573 ± 0.055	4.712LeuAsn: 4.712 ± 0.068	4.719LeuPro: 4.719 ± 0.083	4.648LeuGln: 4.648 ± 0.087	3.683LeuArg: 3.683 ± 0.071	6.145LeuSer: 6.145 ± 0.087	7.503LeuThr: 7.503 ± 0.101	6.934LeuVal: 6.934 ± 0.094	0.97LeuTrp: 0.97 ± 0.033	2.83LeuTyr: 2.83 ± 0.057	0.0LeuXaa: 0.0 ± 0.0
Met	2.904MetAla: 2.904 ± 0.056	0.123MetCys: 0.123 ± 0.014	1.266MetAsp: 1.266 ± 0.035	0.787MetGlu: 0.787 ± 0.031	0.86MetPhe: 0.86 ± 0.028	1.781MetGly: 1.781 ± 0.044	0.455MetHis: 0.455 ± 0.02	1.896MetIle: 1.896 ± 0.052	1.456MetLys: 1.456 ± 0.04	2.333MetLeu: 2.333 ± 0.05	0.689MetMet: 0.689 ± 0.031	1.22MetAsn: 1.22 ± 0.037	1.169MetPro: 1.169 ± 0.035	1.096MetGln: 1.096 ± 0.033	0.96MetArg: 0.96 ± 0.035	1.491MetSer: 1.491 ± 0.04	1.946MetThr: 1.946 ± 0.046	1.817MetVal: 1.817 ± 0.045	0.166MetTrp: 0.166 ± 0.015	0.635MetTyr: 0.635 ± 0.025	0.0MetXaa: 0.0 ± 0.0
Asn	3.588AsnAla: 3.588 ± 0.066	0.24AsnCys: 0.24 ± 0.017	2.595AsnAsp: 2.595 ± 0.052	1.978AsnGlu: 1.978 ± 0.043	2.12AsnPhe: 2.12 ± 0.05	3.324AsnGly: 3.324 ± 0.069	1.165AsnHis: 1.165 ± 0.037	3.084AsnIle: 3.084 ± 0.062	2.236AsnLys: 2.236 ± 0.056	4.599AsnLeu: 4.599 ± 0.067	1.195AsnMet: 1.195 ± 0.034	2.278AsnAsn: 2.278 ± 0.06	2.306AsnPro: 2.306 ± 0.063	2.694AsnGln: 2.694 ± 0.056	1.91AsnArg: 1.91 ± 0.052	2.341AsnSer: 2.341 ± 0.054	2.713AsnThr: 2.713 ± 0.055	3.071AsnVal: 3.071 ± 0.062	0.626AsnTrp: 0.626 ± 0.027	1.846AsnTyr: 1.846 ± 0.051	0.002AsnXaa: 0.002 ± 0.001
Pro	3.685ProAla: 3.685 ± 0.071	0.185ProCys: 0.185 ± 0.014	2.683ProAsp: 2.683 ± 0.052	2.755ProGlu: 2.755 ± 0.054	1.71ProPhe: 1.71 ± 0.044	2.676ProGly: 2.676 ± 0.073	0.681ProHis: 0.681 ± 0.026	2.763ProIle: 2.763 ± 0.047	2.877ProLys: 2.877 ± 0.063	3.863ProLeu: 3.863 ± 0.066	0.89ProMet: 0.89 ± 0.033	2.036ProAsn: 2.036 ± 0.048	0.746ProPro: 0.746 ± 0.029	1.957ProGln: 1.957 ± 0.041	1.177ProArg: 1.177 ± 0.037	1.952ProSer: 1.952 ± 0.047	2.862ProThr: 2.862 ± 0.077	3.094ProVal: 3.094 ± 0.057	0.441ProTrp: 0.441 ± 0.023	1.427ProTyr: 1.427 ± 0.04	0.001ProXaa: 0.001 ± 0.001
Gln	5.506GlnAla: 5.506 ± 0.097	0.146GlnCys: 0.146 ± 0.013	2.585GlnAsp: 2.585 ± 0.047	2.068GlnGlu: 2.068 ± 0.05	1.84GlnPhe: 1.84 ± 0.045	2.923GlnGly: 2.923 ± 0.057	1.181GlnHis: 1.181 ± 0.035	3.347GlnIle: 3.347 ± 0.064	3.061GlnLys: 3.061 ± 0.063	5.883GlnLeu: 5.883 ± 0.108	1.258GlnMet: 1.258 ± 0.037	2.387GlnAsn: 2.387 ± 0.058	2.064GlnPro: 2.064 ± 0.051	3.72GlnGln: 3.72 ± 0.103	2.561GlnArg: 2.561 ± 0.059	2.41GlnSer: 2.41 ± 0.05	3.444GlnThr: 3.444 ± 0.061	3.9GlnVal: 3.9 ± 0.069	0.712GlnTrp: 0.712 ± 0.035	1.688GlnTyr: 1.688 ± 0.038	0.0GlnXaa: 0.0 ± 0.0
Arg	2.716ArgAla: 2.716 ± 0.056	0.217ArgCys: 0.217 ± 0.015	2.01ArgAsp: 2.01 ± 0.042	1.654ArgGlu: 1.654 ± 0.042	1.901ArgPhe: 1.901 ± 0.047	2.122ArgGly: 2.122 ± 0.049	1.056ArgHis: 1.056 ± 0.035	2.631ArgIle: 2.631 ± 0.053	2.098ArgLys: 2.098 ± 0.048	4.089ArgLeu: 4.089 ± 0.07	0.929ArgMet: 0.929 ± 0.029	1.638ArgAsn: 1.638 ± 0.047	1.516ArgPro: 1.516 ± 0.041	2.705ArgGln: 2.705 ± 0.069	1.972ArgArg: 1.972 ± 0.047	1.844ArgSer: 1.844 ± 0.044	2.014ArgThr: 2.014 ± 0.047	2.361ArgVal: 2.361 ± 0.05	0.416ArgTrp: 0.416 ± 0.02	1.653ArgTyr: 1.653 ± 0.043	0.001ArgXaa: 0.001 ± 0.001
Ser	4.586SerAla: 4.586 ± 0.083	0.269SerCys: 0.269 ± 0.018	3.238SerAsp: 3.238 ± 0.068	2.638SerGlu: 2.638 ± 0.053	2.527SerPhe: 2.527 ± 0.056	4.556SerGly: 4.556 ± 0.083	1.14SerHis: 1.14 ± 0.034	3.562SerIle: 3.562 ± 0.057	2.962SerLys: 2.962 ± 0.058	5.376SerLeu: 5.376 ± 0.094	1.294SerMet: 1.294 ± 0.035	2.394SerAsn: 2.394 ± 0.05	1.939SerPro: 1.939 ± 0.039	2.847SerGln: 2.847 ± 0.056	2.039SerArg: 2.039 ± 0.045	3.081SerSer: 3.081 ± 0.093	3.183SerThr: 3.183 ± 0.065	3.569SerVal: 3.569 ± 0.059	0.651SerTrp: 0.651 ± 0.026	1.943SerTyr: 1.943 ± 0.045	0.001SerXaa: 0.001 ± 0.001
Thr	6.088ThrAla: 6.088 ± 0.098	0.294ThrCys: 0.294 ± 0.019	3.63ThrAsp: 3.63 ± 0.072	2.605ThrGlu: 2.605 ± 0.05	2.634ThrPhe: 2.634 ± 0.049	4.88ThrGly: 4.88 ± 0.076	1.229ThrHis: 1.229 ± 0.034	4.741ThrIle: 4.741 ± 0.067	3.759ThrLys: 3.759 ± 0.06	6.624ThrLeu: 6.624 ± 0.079	1.42ThrMet: 1.42 ± 0.04	2.958ThrAsn: 2.958 ± 0.064	3.435ThrPro: 3.435 ± 0.107	3.111ThrGln: 3.111 ± 0.063	2.036ThrArg: 2.036 ± 0.046	3.516ThrSer: 3.516 ± 0.072	5.068ThrThr: 5.068 ± 0.138	4.751ThrVal: 4.751 ± 0.085	0.744ThrTrp: 0.744 ± 0.029	2.377ThrTyr: 2.377 ± 0.05	0.001ThrXaa: 0.001 ± 0.001
Val	7.151ValAla: 7.151 ± 0.105	0.41ValCys: 0.41 ± 0.023	3.973ValAsp: 3.973 ± 0.07	2.592ValGlu: 2.592 ± 0.056	2.882ValPhe: 2.882 ± 0.06	5.001ValGly: 5.001 ± 0.079	1.215ValHis: 1.215 ± 0.034	5.111ValIle: 5.111 ± 0.071	3.805ValLys: 3.805 ± 0.074	7.213ValLeu: 7.213 ± 0.119	1.741ValMet: 1.741 ± 0.048	3.146ValAsn: 3.146 ± 0.058	2.918ValPro: 2.918 ± 0.058	3.039ValGln: 3.039 ± 0.051	2.252ValArg: 2.252 ± 0.051	4.133ValSer: 4.133 ± 0.07	5.057ValThr: 5.057 ± 0.081	5.235ValVal: 5.235 ± 0.088	0.588ValTrp: 0.588 ± 0.025	2.227ValTyr: 2.227 ± 0.051	0.0ValXaa: 0.0 ± 0.0
Trp	0.804TrpAla: 0.804 ± 0.029	0.056TrpCys: 0.056 ± 0.007	0.515TrpAsp: 0.515 ± 0.024	0.34TrpGlu: 0.34 ± 0.018	0.564TrpPhe: 0.564 ± 0.022	0.713TrpGly: 0.713 ± 0.028	0.313TrpHis: 0.313 ± 0.018	0.677TrpIle: 0.677 ± 0.028	0.275TrpLys: 0.275 ± 0.019	1.487TrpLeu: 1.487 ± 0.042	0.195TrpMet: 0.195 ± 0.013	0.418TrpAsn: 0.418 ± 0.024	0.375TrpPro: 0.375 ± 0.019	0.879TrpGln: 0.879 ± 0.031	0.554TrpArg: 0.554 ± 0.024	0.517TrpSer: 0.517 ± 0.023	0.585TrpThr: 0.585 ± 0.023	0.796TrpVal: 0.796 ± 0.033	0.158TrpTrp: 0.158 ± 0.015	0.406TrpTyr: 0.406 ± 0.023	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.637TyrAla: 2.637 ± 0.062	0.222TyrCys: 0.222 ± 0.015	2.275TyrAsp: 2.275 ± 0.055	1.592TyrGlu: 1.592 ± 0.041	1.833TyrPhe: 1.833 ± 0.044	2.577TyrGly: 2.577 ± 0.062	0.981TyrHis: 0.981 ± 0.036	1.999TyrIle: 1.999 ± 0.045	1.509TyrLys: 1.509 ± 0.04	3.983TyrLeu: 3.983 ± 0.066	0.739TyrMet: 0.739 ± 0.024	1.543TyrAsn: 1.543 ± 0.041	1.52TyrPro: 1.52 ± 0.039	2.388TyrGln: 2.388 ± 0.054	1.642TyrArg: 1.642 ± 0.038	1.699TyrSer: 1.699 ± 0.048	2.074TyrThr: 2.074 ± 0.049	2.223TyrVal: 2.223 ± 0.051	0.454TyrTrp: 0.454 ± 0.024	1.498TyrTyr: 1.498 ± 0.042	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.001XaaAla: 0.001 ± 0.001	0.0XaaCys: 0.0 ± 0.0	0.001XaaAsp: 0.001 ± 0.001	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.001XaaGly: 0.001 ± 0.001	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.001XaaLys: 0.001 ± 0.001	0.0XaaLeu: 0.0 ± 0.0	0.001XaaMet: 0.001 ± 0.001	0.004XaaAsn: 0.004 ± 0.002	0.002XaaPro: 0.002 ± 0.001	0.001XaaGln: 0.001 ± 0.001	0.001XaaArg: 0.001 ± 0.001	0.003XaaSer: 0.003 ± 0.002	0.0XaaThr: 0.0 ± 0.0	0.001XaaVal: 0.001 ± 0.001	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.091XaaXaa: 0.091 ± 0.034

Statistics based on 3260 proteins (1004349 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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