Amino acid dipepetide frequency for Silvanigrellales bacterium RF1110005

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	4.606AlaAla: 4.606 ± 0.105	0.803AlaCys: 0.803 ± 0.031	2.837AlaAsp: 2.837 ± 0.052	3.914AlaGlu: 3.914 ± 0.08	3.178AlaPhe: 3.178 ± 0.056	3.801AlaGly: 3.801 ± 0.071	1.394AlaHis: 1.394 ± 0.035	5.238AlaIle: 5.238 ± 0.073	5.411AlaLys: 5.411 ± 0.083	6.69AlaLeu: 6.69 ± 0.078	1.448AlaMet: 1.448 ± 0.043	3.522AlaAsn: 3.522 ± 0.07	1.894AlaPro: 1.894 ± 0.055	2.853AlaGln: 2.853 ± 0.056	2.586AlaArg: 2.586 ± 0.05	4.323AlaSer: 4.323 ± 0.081	2.942AlaThr: 2.942 ± 0.066	3.548AlaVal: 3.548 ± 0.071	0.608AlaTrp: 0.608 ± 0.025	1.962AlaTyr: 1.962 ± 0.048	0.0AlaXaa: 0.0 ± 0.0
Cys	0.796CysAla: 0.796 ± 0.028	0.149CysCys: 0.149 ± 0.011	0.618CysAsp: 0.618 ± 0.025	0.753CysGlu: 0.753 ± 0.029	0.681CysPhe: 0.681 ± 0.027	0.83CysGly: 0.83 ± 0.032	0.295CysHis: 0.295 ± 0.018	0.973CysIle: 0.973 ± 0.031	0.761CysLys: 0.761 ± 0.027	1.219CysLeu: 1.219 ± 0.038	0.206CysMet: 0.206 ± 0.014	0.549CysAsn: 0.549 ± 0.029	0.437CysPro: 0.437 ± 0.023	0.395CysGln: 0.395 ± 0.021	0.39CysArg: 0.39 ± 0.02	0.927CysSer: 0.927 ± 0.028	0.563CysThr: 0.563 ± 0.024	0.672CysVal: 0.672 ± 0.028	0.11CysTrp: 0.11 ± 0.014	0.43CysTyr: 0.43 ± 0.02	0.0CysXaa: 0.0 ± 0.0
Asp	2.745AspAla: 2.745 ± 0.061	0.557AspCys: 0.557 ± 0.024	2.217AspAsp: 2.217 ± 0.06	3.305AspGlu: 3.305 ± 0.063	3.08AspPhe: 3.08 ± 0.059	2.566AspGly: 2.566 ± 0.054	0.838AspHis: 0.838 ± 0.029	4.449AspIle: 4.449 ± 0.075	4.037AspLys: 4.037 ± 0.066	5.067AspLeu: 5.067 ± 0.075	0.899AspMet: 0.899 ± 0.028	2.611AspAsn: 2.611 ± 0.064	1.882AspPro: 1.882 ± 0.045	1.223AspGln: 1.223 ± 0.037	1.652AspArg: 1.652 ± 0.037	3.336AspSer: 3.336 ± 0.052	1.917AspThr: 1.917 ± 0.044	2.506AspVal: 2.506 ± 0.05	0.55AspTrp: 0.55 ± 0.02	1.858AspTyr: 1.858 ± 0.047	0.0AspXaa: 0.0 ± 0.0
Glu	3.723GluAla: 3.723 ± 0.076	0.618GluCys: 0.618 ± 0.025	2.758GluAsp: 2.758 ± 0.051	4.495GluGlu: 4.495 ± 0.08	3.268GluPhe: 3.268 ± 0.056	2.842GluGly: 2.842 ± 0.061	1.222GluHis: 1.222 ± 0.037	6.409GluIle: 6.409 ± 0.086	7.181GluLys: 7.181 ± 0.099	6.063GluLeu: 6.063 ± 0.096	1.543GluMet: 1.543 ± 0.046	5.702GluAsn: 5.702 ± 0.081	1.485GluPro: 1.485 ± 0.041	2.285GluGln: 2.285 ± 0.046	2.814GluArg: 2.814 ± 0.057	4.103GluSer: 4.103 ± 0.071	2.991GluThr: 2.991 ± 0.05	3.419GluVal: 3.419 ± 0.066	0.593GluTrp: 0.593 ± 0.026	2.248GluTyr: 2.248 ± 0.051	0.0GluXaa: 0.0 ± 0.0
Phe	3.556PheAla: 3.556 ± 0.057	0.784PheCys: 0.784 ± 0.03	2.699PheAsp: 2.699 ± 0.055	3.211PheGlu: 3.211 ± 0.058	3.123PhePhe: 3.123 ± 0.07	3.083PheGly: 3.083 ± 0.063	1.003PheHis: 1.003 ± 0.03	5.023PheIle: 5.023 ± 0.088	3.719PheLys: 3.719 ± 0.066	5.606PheLeu: 5.606 ± 0.103	1.041PheMet: 1.041 ± 0.033	2.821PheAsn: 2.821 ± 0.058	1.985PhePro: 1.985 ± 0.048	1.781PheGln: 1.781 ± 0.037	1.658PheArg: 1.658 ± 0.039	4.952PheSer: 4.952 ± 0.077	2.395PheThr: 2.395 ± 0.042	2.914PheVal: 2.914 ± 0.061	0.561PheTrp: 0.561 ± 0.029	2.112PheTyr: 2.112 ± 0.053	0.0PheXaa: 0.0 ± 0.0
Gly	3.724GlyAla: 3.724 ± 0.072	0.727GlyCys: 0.727 ± 0.029	2.463GlyAsp: 2.463 ± 0.053	3.094GlyGlu: 3.094 ± 0.062	3.229GlyPhe: 3.229 ± 0.065	3.726GlyGly: 3.726 ± 0.092	1.06GlyHis: 1.06 ± 0.031	5.027GlyIle: 5.027 ± 0.075	4.589GlyLys: 4.589 ± 0.073	4.932GlyLeu: 4.932 ± 0.08	1.382GlyMet: 1.382 ± 0.038	2.875GlyAsn: 2.875 ± 0.06	1.276GlyPro: 1.276 ± 0.053	1.693GlyGln: 1.693 ± 0.04	2.14GlyArg: 2.14 ± 0.05	3.699GlySer: 3.699 ± 0.065	2.907GlyThr: 2.907 ± 0.062	3.647GlyVal: 3.647 ± 0.063	0.635GlyTrp: 0.635 ± 0.029	2.114GlyTyr: 2.114 ± 0.044	0.0GlyXaa: 0.0 ± 0.0
His	1.227HisAla: 1.227 ± 0.029	0.279HisCys: 0.279 ± 0.014	0.855HisAsp: 0.855 ± 0.028	1.223HisGlu: 1.223 ± 0.033	1.267HisPhe: 1.267 ± 0.036	1.091HisGly: 1.091 ± 0.033	0.426HisHis: 0.426 ± 0.025	1.553HisIle: 1.553 ± 0.042	1.347HisLys: 1.347 ± 0.037	1.846HisLeu: 1.846 ± 0.044	0.399HisMet: 0.399 ± 0.019	1.061HisAsn: 1.061 ± 0.029	0.901HisPro: 0.901 ± 0.035	0.439HisGln: 0.439 ± 0.02	0.663HisArg: 0.663 ± 0.026	1.506HisSer: 1.506 ± 0.038	0.892HisThr: 0.892 ± 0.031	0.954HisVal: 0.954 ± 0.03	0.237HisTrp: 0.237 ± 0.014	0.698HisTyr: 0.698 ± 0.026	0.0HisXaa: 0.0 ± 0.0
Ile	5.983IleAla: 5.983 ± 0.088	1.119IleCys: 1.119 ± 0.029	4.641IleAsp: 4.641 ± 0.073	6.031IleGlu: 6.031 ± 0.089	4.893IlePhe: 4.893 ± 0.087	4.782IleGly: 4.782 ± 0.078	1.695IleHis: 1.695 ± 0.044	7.212IleIle: 7.212 ± 0.093	6.538IleLys: 6.538 ± 0.084	9.141IleLeu: 9.141 ± 0.107	1.526IleMet: 1.526 ± 0.044	5.185IleAsn: 5.185 ± 0.088	3.678IlePro: 3.678 ± 0.066	2.985IleGln: 2.985 ± 0.054	2.954IleArg: 2.954 ± 0.053	7.288IleSer: 7.288 ± 0.09	3.905IleThr: 3.905 ± 0.071	4.653IleVal: 4.653 ± 0.074	0.746IleTrp: 0.746 ± 0.029	3.092IleTyr: 3.092 ± 0.065	0.0IleXaa: 0.0 ± 0.0
Lys	4.159LysAla: 4.159 ± 0.059	0.797LysCys: 0.797 ± 0.029	3.943LysAsp: 3.943 ± 0.072	6.221LysGlu: 6.221 ± 0.101	3.454LysPhe: 3.454 ± 0.066	3.431LysGly: 3.431 ± 0.059	1.2LysHis: 1.2 ± 0.032	8.613LysIle: 8.613 ± 0.105	8.118LysLys: 8.118 ± 0.121	7.296LysLeu: 7.296 ± 0.097	1.975LysMet: 1.975 ± 0.047	7.262LysAsn: 7.262 ± 0.108	2.231LysPro: 2.231 ± 0.043	2.417LysGln: 2.417 ± 0.058	2.881LysArg: 2.881 ± 0.066	5.93LysSer: 5.93 ± 0.081	4.055LysThr: 4.055 ± 0.065	4.495LysVal: 4.495 ± 0.08	0.723LysTrp: 0.723 ± 0.029	3.34LysTyr: 3.34 ± 0.062	0.0LysXaa: 0.0 ± 0.0
Leu	6.763LeuAla: 6.763 ± 0.088	1.229LeuCys: 1.229 ± 0.039	4.69LeuAsp: 4.69 ± 0.063	6.332LeuGlu: 6.332 ± 0.097	5.27LeuPhe: 5.27 ± 0.102	5.549LeuGly: 5.549 ± 0.083	1.763LeuHis: 1.763 ± 0.039	7.773LeuIle: 7.773 ± 0.116	8.634LeuLys: 8.634 ± 0.105	9.115LeuLeu: 9.115 ± 0.117	1.968LeuMet: 1.968 ± 0.045	6.926LeuAsn: 6.926 ± 0.088	3.898LeuPro: 3.898 ± 0.064	3.375LeuGln: 3.375 ± 0.057	3.811LeuArg: 3.811 ± 0.07	8.493LeuSer: 8.493 ± 0.097	4.851LeuThr: 4.851 ± 0.054	4.873LeuVal: 4.873 ± 0.079	0.817LeuTrp: 0.817 ± 0.03	2.951LeuTyr: 2.951 ± 0.063	0.0LeuXaa: 0.0 ± 0.0
Met	1.32MetAla: 1.32 ± 0.04	0.23MetCys: 0.23 ± 0.016	0.915MetAsp: 0.915 ± 0.025	1.141MetGlu: 1.141 ± 0.035	0.767MetPhe: 0.767 ± 0.023	1.315MetGly: 1.315 ± 0.033	0.496MetHis: 0.496 ± 0.021	1.552MetIle: 1.552 ± 0.041	1.776MetLys: 1.776 ± 0.042	1.995MetLeu: 1.995 ± 0.041	0.425MetMet: 0.425 ± 0.022	1.41MetAsn: 1.41 ± 0.035	0.903MetPro: 0.903 ± 0.029	1.034MetGln: 1.034 ± 0.035	1.081MetArg: 1.081 ± 0.035	1.766MetSer: 1.766 ± 0.036	1.15MetThr: 1.15 ± 0.032	0.95MetVal: 0.95 ± 0.032	0.139MetTrp: 0.139 ± 0.013	0.495MetTyr: 0.495 ± 0.021	0.0MetXaa: 0.0 ± 0.0
Asn	3.624AsnAla: 3.624 ± 0.061	0.713AsnCys: 0.713 ± 0.027	2.93AsnAsp: 2.93 ± 0.054	4.182AsnGlu: 4.182 ± 0.073	3.415AsnPhe: 3.415 ± 0.064	3.118AsnGly: 3.118 ± 0.06	1.081AsnHis: 1.081 ± 0.036	6.469AsnIle: 6.469 ± 0.1	5.611AsnLys: 5.611 ± 0.079	6.449AsnLeu: 6.449 ± 0.098	1.312AsnMet: 1.312 ± 0.032	4.367AsnAsn: 4.367 ± 0.086	2.597AsnPro: 2.597 ± 0.055	2.047AsnGln: 2.047 ± 0.049	2.019AsnArg: 2.019 ± 0.04	5.13AsnSer: 5.13 ± 0.077	2.794AsnThr: 2.794 ± 0.062	2.855AsnVal: 2.855 ± 0.055	0.697AsnTrp: 0.697 ± 0.026	2.611AsnTyr: 2.611 ± 0.06	0.0AsnXaa: 0.0 ± 0.0
Pro	2.058ProAla: 2.058 ± 0.057	0.332ProCys: 0.332 ± 0.021	1.699ProAsp: 1.699 ± 0.04	2.656ProGlu: 2.656 ± 0.052	2.062ProPhe: 2.062 ± 0.05	1.661ProGly: 1.661 ± 0.049	0.746ProHis: 0.746 ± 0.026	3.029ProIle: 3.029 ± 0.052	2.743ProLys: 2.743 ± 0.047	3.291ProLeu: 3.291 ± 0.061	0.676ProMet: 0.676 ± 0.027	2.121ProAsn: 2.121 ± 0.048	1.134ProPro: 1.134 ± 0.041	1.344ProGln: 1.344 ± 0.046	1.106ProArg: 1.106 ± 0.035	2.451ProSer: 2.451 ± 0.046	1.793ProThr: 1.793 ± 0.044	2.086ProVal: 2.086 ± 0.043	0.432ProTrp: 0.432 ± 0.022	1.295ProTyr: 1.295 ± 0.038	0.0ProXaa: 0.0 ± 0.0
Gln	2.299GlnAla: 2.299 ± 0.048	0.315GlnCys: 0.315 ± 0.017	1.501GlnAsp: 1.501 ± 0.037	2.439GlnGlu: 2.439 ± 0.046	1.677GlnPhe: 1.677 ± 0.038	1.748GlnGly: 1.748 ± 0.065	0.534GlnHis: 0.534 ± 0.024	3.177GlnIle: 3.177 ± 0.049	3.36GlnLys: 3.36 ± 0.066	2.987GlnLeu: 2.987 ± 0.061	0.819GlnMet: 0.819 ± 0.029	2.841GlnAsn: 2.841 ± 0.05	0.9GlnPro: 0.9 ± 0.031	1.128GlnGln: 1.128 ± 0.032	1.312GlnArg: 1.312 ± 0.042	2.459GlnSer: 2.459 ± 0.057	1.772GlnThr: 1.772 ± 0.043	1.778GlnVal: 1.778 ± 0.041	0.314GlnTrp: 0.314 ± 0.017	1.151GlnTyr: 1.151 ± 0.036	0.0GlnXaa: 0.0 ± 0.0
Arg	2.415ArgAla: 2.415 ± 0.051	0.377ArgCys: 0.377 ± 0.021	1.736ArgAsp: 1.736 ± 0.038	2.592ArgGlu: 2.592 ± 0.056	1.882ArgPhe: 1.882 ± 0.047	1.912ArgGly: 1.912 ± 0.05	0.621ArgHis: 0.621 ± 0.025	3.348ArgIle: 3.348 ± 0.056	3.15ArgLys: 3.15 ± 0.059	3.398ArgLeu: 3.398 ± 0.059	0.933ArgMet: 0.933 ± 0.028	2.436ArgAsn: 2.436 ± 0.056	1.178ArgPro: 1.178 ± 0.037	1.148ArgGln: 1.148 ± 0.034	1.541ArgArg: 1.541 ± 0.043	2.449ArgSer: 2.449 ± 0.047	1.727ArgThr: 1.727 ± 0.044	2.192ArgVal: 2.192 ± 0.052	0.338ArgTrp: 0.338 ± 0.018	1.309ArgTyr: 1.309 ± 0.032	0.0ArgXaa: 0.0 ± 0.0
Ser	4.881SerAla: 4.881 ± 0.091	0.875SerCys: 0.875 ± 0.03	3.634SerAsp: 3.634 ± 0.059	5.134SerGlu: 5.134 ± 0.075	4.509SerPhe: 4.509 ± 0.08	4.46SerGly: 4.46 ± 0.067	1.53SerHis: 1.53 ± 0.037	6.583SerIle: 6.583 ± 0.086	4.924SerLys: 4.924 ± 0.076	8.618SerLeu: 8.618 ± 0.117	1.551SerMet: 1.551 ± 0.041	4.047SerAsn: 4.047 ± 0.074	2.653SerPro: 2.653 ± 0.05	2.911SerGln: 2.911 ± 0.058	2.555SerArg: 2.555 ± 0.052	5.948SerSer: 5.948 ± 0.101	3.549SerThr: 3.549 ± 0.067	4.29SerVal: 4.29 ± 0.076	0.677SerTrp: 0.677 ± 0.024	2.74SerTyr: 2.74 ± 0.053	0.0SerXaa: 0.0 ± 0.0
Thr	3.271ThrAla: 3.271 ± 0.067	0.53ThrCys: 0.53 ± 0.024	2.208ThrAsp: 2.208 ± 0.046	2.908ThrGlu: 2.908 ± 0.05	2.438ThrPhe: 2.438 ± 0.051	3.167ThrGly: 3.167 ± 0.06	1.084ThrHis: 1.084 ± 0.03	3.554ThrIle: 3.554 ± 0.066	3.398ThrLys: 3.398 ± 0.054	5.117ThrLeu: 5.117 ± 0.064	0.802ThrMet: 0.802 ± 0.028	2.666ThrAsn: 2.666 ± 0.058	2.016ThrPro: 2.016 ± 0.053	1.976ThrGln: 1.976 ± 0.04	1.749ThrArg: 1.749 ± 0.045	3.559ThrSer: 3.559 ± 0.074	2.353ThrThr: 2.353 ± 0.067	2.751ThrVal: 2.751 ± 0.058	0.487ThrTrp: 0.487 ± 0.021	1.679ThrTyr: 1.679 ± 0.048	0.0ThrXaa: 0.0 ± 0.0
Val	3.648ValAla: 3.648 ± 0.067	0.706ValCys: 0.706 ± 0.026	2.713ValAsp: 2.713 ± 0.058	3.417ValGlu: 3.417 ± 0.067	2.91ValPhe: 2.91 ± 0.065	3.356ValGly: 3.356 ± 0.064	1.042ValHis: 1.042 ± 0.033	4.402ValIle: 4.402 ± 0.069	3.837ValLys: 3.837 ± 0.072	5.265ValLeu: 5.265 ± 0.072	1.049ValMet: 1.049 ± 0.031	2.985ValAsn: 2.985 ± 0.057	2.019ValPro: 2.019 ± 0.044	1.845ValGln: 1.845 ± 0.041	2.088ValArg: 2.088 ± 0.049	4.186ValSer: 4.186 ± 0.071	3.067ValThr: 3.067 ± 0.069	3.311ValVal: 3.311 ± 0.069	0.499ValTrp: 0.499 ± 0.024	1.791ValTyr: 1.791 ± 0.043	0.0ValXaa: 0.0 ± 0.0
Trp	0.529TrpAla: 0.529 ± 0.027	0.145TrpCys: 0.145 ± 0.011	0.483TrpAsp: 0.483 ± 0.02	0.59TrpGlu: 0.59 ± 0.023	0.494TrpPhe: 0.494 ± 0.02	0.543TrpGly: 0.543 ± 0.026	0.226TrpHis: 0.226 ± 0.014	0.765TrpIle: 0.765 ± 0.028	0.753TrpLys: 0.753 ± 0.027	1.075TrpLeu: 1.075 ± 0.034	0.216TrpMet: 0.216 ± 0.014	0.603TrpAsn: 0.603 ± 0.022	0.33TrpPro: 0.33 ± 0.021	0.467TrpGln: 0.467 ± 0.022	0.427TrpArg: 0.427 ± 0.018	0.684TrpSer: 0.684 ± 0.026	0.395TrpThr: 0.395 ± 0.02	0.534TrpVal: 0.534 ± 0.024	0.119TrpTrp: 0.119 ± 0.011	0.328TrpTyr: 0.328 ± 0.019	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.231TyrAla: 2.231 ± 0.05	0.467TyrCys: 0.467 ± 0.024	1.756TyrAsp: 1.756 ± 0.044	2.12TyrGlu: 2.12 ± 0.054	2.429TyrPhe: 2.429 ± 0.056	1.957TyrGly: 1.957 ± 0.037	0.61TyrHis: 0.61 ± 0.024	2.898TyrIle: 2.898 ± 0.068	2.652TyrLys: 2.652 ± 0.058	3.913TyrLeu: 3.913 ± 0.068	0.691TyrMet: 0.691 ± 0.03	2.036TyrAsn: 2.036 ± 0.046	1.319TyrPro: 1.319 ± 0.035	1.163TyrGln: 1.163 ± 0.035	1.254TyrArg: 1.254 ± 0.036	2.882TyrSer: 2.882 ± 0.059	1.694TyrThr: 1.694 ± 0.045	1.707TyrVal: 1.707 ± 0.038	0.424TyrTrp: 0.424 ± 0.022	1.514TyrTyr: 1.514 ± 0.045	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3167 proteins (1068353 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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