Amino acid dipepetide frequency for Harpegnathos saltator (Jerdon s jumping ant)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	5.864AlaAla: 5.864 ± 0.055	1.45AlaCys: 1.45 ± 0.046	3.265AlaAsp: 3.265 ± 0.029	4.379AlaGlu: 4.379 ± 0.049	2.102AlaPhe: 2.102 ± 0.02	3.701AlaGly: 3.701 ± 0.037	1.457AlaHis: 1.457 ± 0.018	3.544AlaIle: 3.544 ± 0.029	3.83AlaLys: 3.83 ± 0.044	5.847AlaLeu: 5.847 ± 0.042	1.573AlaMet: 1.573 ± 0.017	2.845AlaAsn: 2.845 ± 0.027	2.867AlaPro: 2.867 ± 0.034	2.496AlaGln: 2.496 ± 0.024	3.846AlaArg: 3.846 ± 0.033	5.261AlaSer: 5.261 ± 0.043	4.226AlaThr: 4.226 ± 0.037	4.249AlaVal: 4.249 ± 0.032	0.652AlaTrp: 0.652 ± 0.011	1.718AlaTyr: 1.718 ± 0.017	0.0AlaXaa: 0.0 ± 0.0
Cys	1.163CysAla: 1.163 ± 0.019	0.47CysCys: 0.47 ± 0.011	1.139CysAsp: 1.139 ± 0.02	1.172CysGlu: 1.172 ± 0.021	0.735CysPhe: 0.735 ± 0.012	1.296CysGly: 1.296 ± 0.032	0.538CysHis: 0.538 ± 0.01	1.157CysIle: 1.157 ± 0.024	1.128CysLys: 1.128 ± 0.018	1.889CysLeu: 1.889 ± 0.033	0.48CysMet: 0.48 ± 0.015	0.959CysAsn: 0.959 ± 0.017	1.034CysPro: 1.034 ± 0.031	0.783CysGln: 0.783 ± 0.017	1.173CysArg: 1.173 ± 0.033	1.516CysSer: 1.516 ± 0.031	1.115CysThr: 1.115 ± 0.025	1.43CysVal: 1.43 ± 0.043	0.232CysTrp: 0.232 ± 0.007	0.62CysTyr: 0.62 ± 0.012	0.0CysXaa: 0.0 ± 0.0
Asp	3.363AspAla: 3.363 ± 0.037	0.998AspCys: 0.998 ± 0.02	3.984AspAsp: 3.984 ± 0.063	4.36AspGlu: 4.36 ± 0.038	2.102AspPhe: 2.102 ± 0.023	3.161AspGly: 3.161 ± 0.032	1.17AspHis: 1.17 ± 0.014	3.56AspIle: 3.56 ± 0.025	3.351AspLys: 3.351 ± 0.035	4.763AspLeu: 4.763 ± 0.032	1.35AspMet: 1.35 ± 0.015	2.747AspAsn: 2.747 ± 0.026	2.389AspPro: 2.389 ± 0.027	1.677AspGln: 1.677 ± 0.018	2.937AspArg: 2.937 ± 0.037	4.209AspSer: 4.209 ± 0.035	3.013AspThr: 3.013 ± 0.028	3.721AspVal: 3.721 ± 0.032	0.654AspTrp: 0.654 ± 0.012	1.871AspTyr: 1.871 ± 0.02	0.0AspXaa: 0.0 ± 0.0
Glu	4.295GluAla: 4.295 ± 0.042	1.234GluCys: 1.234 ± 0.033	4.285GluAsp: 4.285 ± 0.034	6.761GluGlu: 6.761 ± 0.103	2.044GluPhe: 2.044 ± 0.02	2.989GluGly: 2.989 ± 0.027	1.567GluHis: 1.567 ± 0.017	3.933GluIle: 3.933 ± 0.034	5.158GluLys: 5.158 ± 0.06	5.827GluLeu: 5.827 ± 0.044	1.651GluMet: 1.651 ± 0.022	3.673GluAsn: 3.673 ± 0.032	2.556GluPro: 2.556 ± 0.039	2.926GluGln: 2.926 ± 0.04	4.496GluArg: 4.496 ± 0.062	4.61GluSer: 4.61 ± 0.042	3.912GluThr: 3.912 ± 0.037	3.868GluVal: 3.868 ± 0.038	0.725GluTrp: 0.725 ± 0.013	1.972GluTyr: 1.972 ± 0.017	0.0GluXaa: 0.0 ± 0.0
Phe	2.151PheAla: 2.151 ± 0.023	0.786PheCys: 0.786 ± 0.013	1.956PheAsp: 1.956 ± 0.019	2.081PheGlu: 2.081 ± 0.02	1.437PhePhe: 1.437 ± 0.019	2.09PheGly: 2.09 ± 0.022	0.941PheHis: 0.941 ± 0.013	1.925PheIle: 1.925 ± 0.024	1.914PheLys: 1.914 ± 0.018	3.446PheLeu: 3.446 ± 0.031	0.804PheMet: 0.804 ± 0.012	1.654PheAsn: 1.654 ± 0.019	1.6PhePro: 1.6 ± 0.018	1.347PheGln: 1.347 ± 0.015	1.886PheArg: 1.886 ± 0.021	2.662PheSer: 2.662 ± 0.025	1.946PheThr: 1.946 ± 0.021	2.496PheVal: 2.496 ± 0.034	0.445PheTrp: 0.445 ± 0.01	1.253PheTyr: 1.253 ± 0.018	0.0PheXaa: 0.0 ± 0.0
Gly	3.306GlyAla: 3.306 ± 0.032	1.021GlyCys: 1.021 ± 0.02	2.901GlyAsp: 2.901 ± 0.029	3.209GlyGlu: 3.209 ± 0.035	1.996GlyPhe: 1.996 ± 0.022	4.255GlyGly: 4.255 ± 0.067	1.428GlyHis: 1.428 ± 0.02	3.118GlyIle: 3.118 ± 0.03	3.353GlyLys: 3.353 ± 0.029	4.407GlyLeu: 4.407 ± 0.039	1.223GlyMet: 1.223 ± 0.016	2.631GlyAsn: 2.631 ± 0.024	2.388GlyPro: 2.388 ± 0.04	2.047GlyGln: 2.047 ± 0.024	3.269GlyArg: 3.269 ± 0.037	4.436GlySer: 4.436 ± 0.036	3.175GlyThr: 3.175 ± 0.027	3.224GlyVal: 3.224 ± 0.03	0.671GlyTrp: 0.671 ± 0.012	1.913GlyTyr: 1.913 ± 0.021	0.0GlyXaa: 0.0 ± 0.0
His	1.527HisAla: 1.527 ± 0.025	0.59HisCys: 0.59 ± 0.011	1.199HisAsp: 1.199 ± 0.012	1.455HisGlu: 1.455 ± 0.019	0.963HisPhe: 0.963 ± 0.01	1.413HisGly: 1.413 ± 0.02	1.103HisHis: 1.103 ± 0.024	1.43HisIle: 1.43 ± 0.016	1.321HisLys: 1.321 ± 0.016	2.388HisLeu: 2.388 ± 0.023	0.622HisMet: 0.622 ± 0.011	1.132HisAsn: 1.132 ± 0.016	1.393HisPro: 1.393 ± 0.023	1.109HisGln: 1.109 ± 0.017	1.549HisArg: 1.549 ± 0.018	1.964HisSer: 1.964 ± 0.038	1.393HisThr: 1.393 ± 0.02	1.62HisVal: 1.62 ± 0.017	0.3HisTrp: 0.3 ± 0.007	0.847HisTyr: 0.847 ± 0.012	0.0HisXaa: 0.0 ± 0.0
Ile	3.745IleAla: 3.745 ± 0.029	1.26IleCys: 1.26 ± 0.019	3.143IleAsp: 3.143 ± 0.025	3.651IleGlu: 3.651 ± 0.033	2.13IlePhe: 2.13 ± 0.024	2.956IleGly: 2.956 ± 0.028	1.38IleHis: 1.38 ± 0.023	3.248IleIle: 3.248 ± 0.033	3.311IleLys: 3.311 ± 0.027	5.374IleLeu: 5.374 ± 0.038	1.277IleMet: 1.277 ± 0.017	2.685IleAsn: 2.685 ± 0.03	2.801IlePro: 2.801 ± 0.024	2.171IleGln: 2.171 ± 0.025	2.889IleArg: 2.889 ± 0.022	4.368IleSer: 4.368 ± 0.028	3.317IleThr: 3.317 ± 0.03	3.643IleVal: 3.643 ± 0.03	0.601IleTrp: 0.601 ± 0.012	1.894IleTyr: 1.894 ± 0.03	0.0IleXaa: 0.0 ± 0.0
Lys	3.465LysAla: 3.465 ± 0.033	1.18LysCys: 1.18 ± 0.021	3.574LysAsp: 3.574 ± 0.043	4.907LysGlu: 4.907 ± 0.058	2.017LysPhe: 2.017 ± 0.022	2.59LysGly: 2.59 ± 0.034	1.512LysHis: 1.512 ± 0.017	3.704LysIle: 3.704 ± 0.034	5.321LysLys: 5.321 ± 0.085	5.674LysLeu: 5.674 ± 0.043	1.547LysMet: 1.547 ± 0.018	3.052LysAsn: 3.052 ± 0.03	2.788LysPro: 2.788 ± 0.046	2.72LysGln: 2.72 ± 0.028	3.927LysArg: 3.927 ± 0.035	4.48LysSer: 4.48 ± 0.046	3.485LysThr: 3.485 ± 0.025	3.509LysVal: 3.509 ± 0.025	0.721LysTrp: 0.721 ± 0.012	2.14LysTyr: 2.14 ± 0.023	0.0LysXaa: 0.0 ± 0.0
Leu	6.09LeuAla: 6.09 ± 0.042	1.791LeuCys: 1.791 ± 0.022	4.831LeuAsp: 4.831 ± 0.037	6.125LeuGlu: 6.125 ± 0.043	3.058LeuPhe: 3.058 ± 0.03	4.383LeuGly: 4.383 ± 0.033	2.479LeuHis: 2.479 ± 0.026	4.518LeuIle: 4.518 ± 0.036	5.772LeuLys: 5.772 ± 0.039	8.871LeuLeu: 8.871 ± 0.072	2.096LeuMet: 2.096 ± 0.022	4.072LeuAsn: 4.072 ± 0.033	5.022LeuPro: 5.022 ± 0.046	4.425LeuGln: 4.425 ± 0.039	5.595LeuArg: 5.595 ± 0.041	7.187LeuSer: 7.187 ± 0.047	5.108LeuThr: 5.108 ± 0.044	5.071LeuVal: 5.071 ± 0.038	0.95LeuTrp: 0.95 ± 0.014	2.744LeuTyr: 2.744 ± 0.029	0.0LeuXaa: 0.0 ± 0.0
Met	1.616MetAla: 1.616 ± 0.02	0.441MetCys: 0.441 ± 0.009	1.369MetAsp: 1.369 ± 0.018	1.714MetGlu: 1.714 ± 0.019	0.834MetPhe: 0.834 ± 0.013	1.131MetGly: 1.131 ± 0.019	0.573MetHis: 0.573 ± 0.011	1.253MetIle: 1.253 ± 0.016	1.615MetLys: 1.615 ± 0.018	2.167MetLeu: 2.167 ± 0.021	0.647MetMet: 0.647 ± 0.01	1.082MetAsn: 1.082 ± 0.016	1.153MetPro: 1.153 ± 0.014	1.104MetGln: 1.104 ± 0.016	1.353MetArg: 1.353 ± 0.017	1.871MetSer: 1.871 ± 0.02	1.331MetThr: 1.331 ± 0.016	1.299MetVal: 1.299 ± 0.017	0.259MetTrp: 0.259 ± 0.007	0.776MetTyr: 0.776 ± 0.017	0.0MetXaa: 0.0 ± 0.0
Asn	3.06AsnAla: 3.06 ± 0.031	0.908AsnCys: 0.908 ± 0.016	2.678AsnAsp: 2.678 ± 0.026	3.31AsnGlu: 3.31 ± 0.056	1.727AsnPhe: 1.727 ± 0.021	2.796AsnGly: 2.796 ± 0.032	1.065AsnHis: 1.065 ± 0.017	3.27AsnIle: 3.27 ± 0.034	2.9AsnLys: 2.9 ± 0.028	4.27AsnLeu: 4.27 ± 0.033	1.212AsnMet: 1.212 ± 0.015	2.94AsnAsn: 2.94 ± 0.036	2.188AsnPro: 2.188 ± 0.026	1.717AsnGln: 1.717 ± 0.02	2.358AsnArg: 2.358 ± 0.023	3.709AsnSer: 3.709 ± 0.029	2.72AsnThr: 2.72 ± 0.025	3.443AsnVal: 3.443 ± 0.025	0.513AsnTrp: 0.513 ± 0.01	1.575AsnTyr: 1.575 ± 0.02	0.0AsnXaa: 0.0 ± 0.0
Pro	3.397ProAla: 3.397 ± 0.037	0.837ProCys: 0.837 ± 0.039	2.58ProAsp: 2.58 ± 0.024	3.25ProGlu: 3.25 ± 0.046	1.548ProPhe: 1.548 ± 0.021	2.845ProGly: 2.845 ± 0.065	1.253ProHis: 1.253 ± 0.016	2.501ProIle: 2.501 ± 0.025	2.625ProLys: 2.625 ± 0.033	4.068ProLeu: 4.068 ± 0.032	1.057ProMet: 1.057 ± 0.015	2.169ProAsn: 2.169 ± 0.025	4.298ProPro: 4.298 ± 0.09	2.102ProGln: 2.102 ± 0.027	2.807ProArg: 2.807 ± 0.027	4.408ProSer: 4.408 ± 0.05	3.338ProThr: 3.338 ± 0.043	3.193ProVal: 3.193 ± 0.034	0.498ProTrp: 0.498 ± 0.009	1.506ProTyr: 1.506 ± 0.018	0.0ProXaa: 0.0 ± 0.0
Gln	2.631GlnAla: 2.631 ± 0.037	0.799GlnCys: 0.799 ± 0.019	2.074GlnAsp: 2.074 ± 0.02	2.97GlnGlu: 2.97 ± 0.036	1.325GlnPhe: 1.325 ± 0.017	1.849GlnGly: 1.849 ± 0.023	1.266GlnHis: 1.266 ± 0.019	2.169GlnIle: 2.169 ± 0.021	2.51GlnLys: 2.51 ± 0.023	3.884GlnLeu: 3.884 ± 0.032	0.996GlnMet: 0.996 ± 0.013	2.067GlnAsn: 2.067 ± 0.025	2.158GlnPro: 2.158 ± 0.034	3.806GlnGln: 3.806 ± 0.093	2.689GlnArg: 2.689 ± 0.026	3.012GlnSer: 3.012 ± 0.027	2.298GlnThr: 2.298 ± 0.026	2.309GlnVal: 2.309 ± 0.025	0.471GlnTrp: 0.471 ± 0.01	1.299GlnTyr: 1.299 ± 0.021	0.0GlnXaa: 0.0 ± 0.0
Arg	3.652ArgAla: 3.652 ± 0.046	1.202ArgCys: 1.202 ± 0.02	3.254ArgAsp: 3.254 ± 0.042	4.009ArgGlu: 4.009 ± 0.037	1.987ArgPhe: 1.987 ± 0.02	3.049ArgGly: 3.049 ± 0.032	1.596ArgHis: 1.596 ± 0.017	3.106ArgIle: 3.106 ± 0.025	4.072ArgLys: 4.072 ± 0.034	5.238ArgLeu: 5.238 ± 0.042	1.361ArgMet: 1.361 ± 0.018	2.871ArgAsn: 2.871 ± 0.023	2.756ArgPro: 2.756 ± 0.035	2.539ArgGln: 2.539 ± 0.037	4.589ArgArg: 4.589 ± 0.048	4.752ArgSer: 4.752 ± 0.052	3.335ArgThr: 3.335 ± 0.053	3.144ArgVal: 3.144 ± 0.028	0.681ArgTrp: 0.681 ± 0.012	1.874ArgTyr: 1.874 ± 0.02	0.0ArgXaa: 0.0 ± 0.0
Ser	5.012SerAla: 5.012 ± 0.044	1.483SerCys: 1.483 ± 0.03	4.34SerAsp: 4.34 ± 0.033	4.685SerGlu: 4.685 ± 0.036	2.812SerPhe: 2.812 ± 0.037	4.664SerGly: 4.664 ± 0.038	1.873SerHis: 1.873 ± 0.019	4.078SerIle: 4.078 ± 0.04	4.536SerLys: 4.536 ± 0.036	7.006SerLeu: 7.006 ± 0.056	1.784SerMet: 1.784 ± 0.019	3.839SerAsn: 3.839 ± 0.03	4.534SerPro: 4.534 ± 0.057	3.205SerGln: 3.205 ± 0.03	4.566SerArg: 4.566 ± 0.049	8.48SerSer: 8.48 ± 0.083	5.28SerThr: 5.28 ± 0.047	4.835SerVal: 4.835 ± 0.033	0.833SerTrp: 0.833 ± 0.013	2.277SerTyr: 2.277 ± 0.024	0.0SerXaa: 0.0 ± 0.0
Thr	4.041ThrAla: 4.041 ± 0.028	1.238ThrCys: 1.238 ± 0.026	3.039ThrAsp: 3.039 ± 0.029	3.737ThrGlu: 3.737 ± 0.051	2.041ThrPhe: 2.041 ± 0.022	3.282ThrGly: 3.282 ± 0.032	1.404ThrHis: 1.404 ± 0.04	3.328ThrIle: 3.328 ± 0.025	3.373ThrLys: 3.373 ± 0.028	5.282ThrLeu: 5.282 ± 0.035	1.404ThrMet: 1.404 ± 0.017	2.91ThrAsn: 2.91 ± 0.051	3.258ThrPro: 3.258 ± 0.035	2.146ThrGln: 2.146 ± 0.021	3.007ThrArg: 3.007 ± 0.026	5.339ThrSer: 5.339 ± 0.042	4.581ThrThr: 4.581 ± 0.08	3.946ThrVal: 3.946 ± 0.035	0.677ThrTrp: 0.677 ± 0.013	1.916ThrTyr: 1.916 ± 0.037	0.0ThrXaa: 0.0 ± 0.0
Val	4.374ValAla: 4.374 ± 0.04	1.39ValCys: 1.39 ± 0.029	3.392ValAsp: 3.392 ± 0.026	4.07ValGlu: 4.07 ± 0.037	2.173ValPhe: 2.173 ± 0.023	3.129ValGly: 3.129 ± 0.026	1.504ValHis: 1.504 ± 0.014	3.453ValIle: 3.453 ± 0.032	3.654ValLys: 3.654 ± 0.032	5.565ValLeu: 5.565 ± 0.043	1.402ValMet: 1.402 ± 0.018	2.855ValAsn: 2.855 ± 0.031	3.199ValPro: 3.199 ± 0.027	2.555ValGln: 2.555 ± 0.021	3.595ValArg: 3.595 ± 0.053	4.753ValSer: 4.753 ± 0.031	3.979ValThr: 3.979 ± 0.034	4.048ValVal: 4.048 ± 0.033	0.69ValTrp: 0.69 ± 0.013	1.893ValTyr: 1.893 ± 0.021	0.0ValXaa: 0.0 ± 0.0
Trp	0.618TrpAla: 0.618 ± 0.01	0.232TrpCys: 0.232 ± 0.007	0.631TrpAsp: 0.631 ± 0.012	0.677TrpGlu: 0.677 ± 0.012	0.467TrpPhe: 0.467 ± 0.009	0.559TrpGly: 0.559 ± 0.011	0.298TrpHis: 0.298 ± 0.007	0.696TrpIle: 0.696 ± 0.012	0.719TrpLys: 0.719 ± 0.015	1.143TrpLeu: 1.143 ± 0.016	0.299TrpMet: 0.299 ± 0.007	0.568TrpAsn: 0.568 ± 0.012	0.438TrpPro: 0.438 ± 0.009	0.474TrpGln: 0.474 ± 0.008	0.726TrpArg: 0.726 ± 0.012	0.834TrpSer: 0.834 ± 0.013	0.618TrpThr: 0.618 ± 0.01	0.591TrpVal: 0.591 ± 0.012	0.185TrpTrp: 0.185 ± 0.006	0.371TrpTyr: 0.371 ± 0.008	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.801TyrAla: 1.801 ± 0.02	0.719TyrCys: 0.719 ± 0.013	1.747TyrAsp: 1.747 ± 0.022	1.96TyrGlu: 1.96 ± 0.024	1.321TyrPhe: 1.321 ± 0.02	1.832TyrGly: 1.832 ± 0.021	0.912TyrHis: 0.912 ± 0.015	1.851TyrIle: 1.851 ± 0.026	1.852TyrLys: 1.852 ± 0.019	3.079TyrLeu: 3.079 ± 0.043	0.807TyrMet: 0.807 ± 0.012	1.609TyrAsn: 1.609 ± 0.02	1.461TyrPro: 1.461 ± 0.021	1.231TyrGln: 1.231 ± 0.018	1.809TyrArg: 1.809 ± 0.02	2.272TyrSer: 2.272 ± 0.023	1.781TyrThr: 1.781 ± 0.023	2.03TyrVal: 2.03 ± 0.025	0.385TyrTrp: 0.385 ± 0.01	1.251TyrTyr: 1.251 ± 0.019	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 15029 proteins (6112760 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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