Amino acid dipepetide frequency for Human adenovirus D serotype 8 (HAdV-8) (Human adenovirus 8)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
7.273AlaAla: 7.273 ± 1.516
1.182AlaCys: 1.182 ± 0.422
2.636AlaAsp: 2.636 ± 0.377
3.545AlaGlu: 3.545 ± 0.636
3.091AlaPhe: 3.091 ± 0.427
4.545AlaGly: 4.545 ± 0.683
1.636AlaHis: 1.636 ± 0.363
2.727AlaIle: 2.727 ± 0.533
2.545AlaLys: 2.545 ± 0.414
7.455AlaLeu: 7.455 ± 1.166
1.364AlaMet: 1.364 ± 0.376
2.636AlaAsn: 2.636 ± 0.462
4.455AlaPro: 4.455 ± 0.864
2.545AlaGln: 2.545 ± 0.424
4.909AlaArg: 4.909 ± 0.82
4.545AlaSer: 4.545 ± 0.458
4.455AlaThr: 4.455 ± 0.724
5.182AlaVal: 5.182 ± 0.694
0.727AlaTrp: 0.727 ± 0.241
2.636AlaTyr: 2.636 ± 0.406
0.0AlaXaa: 0.0 ± 0.0
Cys
1.0CysAla: 1.0 ± 0.339
1.182CysCys: 1.182 ± 0.396
1.091CysAsp: 1.091 ± 0.305
1.091CysGlu: 1.091 ± 0.293
0.545CysPhe: 0.545 ± 0.231
1.727CysGly: 1.727 ± 0.455
0.727CysHis: 0.727 ± 0.296
0.636CysIle: 0.636 ± 0.265
1.091CysLys: 1.091 ± 0.337
1.364CysLeu: 1.364 ± 0.404
0.636CysMet: 0.636 ± 0.261
1.182CysAsn: 1.182 ± 0.355
1.182CysPro: 1.182 ± 0.353
0.364CysGln: 0.364 ± 0.184
1.182CysArg: 1.182 ± 0.387
1.182CysSer: 1.182 ± 0.416
1.0CysThr: 1.0 ± 0.422
1.182CysVal: 1.182 ± 0.405
0.455CysTrp: 0.455 ± 0.205
1.455CysTyr: 1.455 ± 0.339
0.0CysXaa: 0.0 ± 0.0
Asp
3.091AspAla: 3.091 ± 0.513
0.818AspCys: 0.818 ± 0.282
1.909AspAsp: 1.909 ± 0.53
4.636AspGlu: 4.636 ± 0.684
1.727AspPhe: 1.727 ± 0.449
3.091AspGly: 3.091 ± 0.679
1.182AspHis: 1.182 ± 0.388
1.727AspIle: 1.727 ± 0.331
2.818AspLys: 2.818 ± 0.504
5.091AspLeu: 5.091 ± 0.997
2.0AspMet: 2.0 ± 0.35
1.636AspAsn: 1.636 ± 0.438
3.455AspPro: 3.455 ± 0.577
1.364AspGln: 1.364 ± 0.337
3.182AspArg: 3.182 ± 0.703
3.636AspSer: 3.636 ± 0.725
2.364AspThr: 2.364 ± 0.439
3.636AspVal: 3.636 ± 0.51
0.636AspTrp: 0.636 ± 0.2
2.091AspTyr: 2.091 ± 0.518
0.0AspXaa: 0.0 ± 0.0
Glu
3.545GluAla: 3.545 ± 0.783
1.0GluCys: 1.0 ± 0.336
4.545GluAsp: 4.545 ± 1.024
7.0GluGlu: 7.0 ± 1.7
1.636GluPhe: 1.636 ± 0.425
3.364GluGly: 3.364 ± 0.632
1.545GluHis: 1.545 ± 0.393
2.909GluIle: 2.909 ± 0.565
2.182GluLys: 2.182 ± 0.389
5.727GluLeu: 5.727 ± 0.98
1.636GluMet: 1.636 ± 0.437
2.545GluAsn: 2.545 ± 0.526
2.818GluPro: 2.818 ± 0.376
3.636GluGln: 3.636 ± 0.638
4.273GluArg: 4.273 ± 0.83
2.273GluSer: 2.273 ± 0.488
3.545GluThr: 3.545 ± 0.704
2.818GluVal: 2.818 ± 0.377
0.727GluTrp: 0.727 ± 0.31
1.273GluTyr: 1.273 ± 0.363
0.0GluXaa: 0.0 ± 0.0
Phe
2.636PheAla: 2.636 ± 0.518
0.909PheCys: 0.909 ± 0.329
2.182PheAsp: 2.182 ± 0.533
1.909PheGlu: 1.909 ± 0.418
1.818PhePhe: 1.818 ± 0.409
1.091PheGly: 1.091 ± 0.385
0.909PheHis: 0.909 ± 0.286
1.455PheIle: 1.455 ± 0.324
1.545PheLys: 1.545 ± 0.404
3.909PheLeu: 3.909 ± 0.659
1.455PheMet: 1.455 ± 0.332
2.545PheAsn: 2.545 ± 0.604
2.273PhePro: 2.273 ± 0.355
1.727PheGln: 1.727 ± 0.295
2.182PheArg: 2.182 ± 0.503
3.455PheSer: 3.455 ± 0.462
2.545PheThr: 2.545 ± 0.477
2.727PheVal: 2.727 ± 0.392
0.091PheTrp: 0.091 ± 0.106
1.455PheTyr: 1.455 ± 0.433
0.0PheXaa: 0.0 ± 0.0
Gly
4.091GlyAla: 4.091 ± 0.712
1.636GlyCys: 1.636 ± 0.595
2.455GlyAsp: 2.455 ± 0.549
3.091GlyGlu: 3.091 ± 0.496
2.455GlyPhe: 2.455 ± 0.492
5.273GlyGly: 5.273 ± 0.87
1.364GlyHis: 1.364 ± 0.383
2.909GlyIle: 2.909 ± 0.438
2.545GlyLys: 2.545 ± 0.612
6.182GlyLeu: 6.182 ± 0.939
1.091GlyMet: 1.091 ± 0.368
3.455GlyAsn: 3.455 ± 0.792
3.182GlyPro: 3.182 ± 0.441
2.364GlyGln: 2.364 ± 0.655
4.909GlyArg: 4.909 ± 0.545
3.455GlySer: 3.455 ± 0.633
3.364GlyThr: 3.364 ± 0.594
4.909GlyVal: 4.909 ± 0.901
0.818GlyTrp: 0.818 ± 0.228
2.0GlyTyr: 2.0 ± 0.448
0.0GlyXaa: 0.0 ± 0.0
His
2.0HisAla: 2.0 ± 0.491
1.091HisCys: 1.091 ± 0.338
0.909HisAsp: 0.909 ± 0.218
1.091HisGlu: 1.091 ± 0.318
0.727HisPhe: 0.727 ± 0.31
1.545HisGly: 1.545 ± 0.395
0.727HisHis: 0.727 ± 0.207
1.182HisIle: 1.182 ± 0.314
0.818HisLys: 0.818 ± 0.345
2.818HisLeu: 2.818 ± 0.653
0.364HisMet: 0.364 ± 0.23
1.182HisAsn: 1.182 ± 0.291
2.0HisPro: 2.0 ± 0.543
1.091HisGln: 1.091 ± 0.322
2.182HisArg: 2.182 ± 0.516
1.636HisSer: 1.636 ± 0.361
1.0HisThr: 1.0 ± 0.241
1.455HisVal: 1.455 ± 0.33
0.545HisTrp: 0.545 ± 0.261
0.455HisTyr: 0.455 ± 0.195
0.0HisXaa: 0.0 ± 0.0
Ile
3.0IleAla: 3.0 ± 0.447
0.818IleCys: 0.818 ± 0.258
1.636IleAsp: 1.636 ± 0.399
1.364IleGlu: 1.364 ± 0.44
1.727IlePhe: 1.727 ± 0.421
2.273IleGly: 2.273 ± 0.49
0.636IleHis: 0.636 ± 0.348
2.273IleIle: 2.273 ± 0.565
3.0IleLys: 3.0 ± 0.712
4.545IleLeu: 4.545 ± 0.583
1.273IleMet: 1.273 ± 0.269
2.364IleAsn: 2.364 ± 0.449
2.545IlePro: 2.545 ± 0.632
1.545IleGln: 1.545 ± 0.432
2.091IleArg: 2.091 ± 0.559
2.091IleSer: 2.091 ± 0.426
3.091IleThr: 3.091 ± 0.768
2.818IleVal: 2.818 ± 0.513
0.455IleTrp: 0.455 ± 0.179
1.545IleTyr: 1.545 ± 0.358
0.0IleXaa: 0.0 ± 0.0
Lys
2.182LysAla: 2.182 ± 0.438
0.909LysCys: 0.909 ± 0.318
1.818LysAsp: 1.818 ± 0.517
2.636LysGlu: 2.636 ± 0.602
1.909LysPhe: 1.909 ± 0.437
2.909LysGly: 2.909 ± 0.55
0.818LysHis: 0.818 ± 0.266
2.727LysIle: 2.727 ± 0.476
3.273LysLys: 3.273 ± 0.54
4.0LysLeu: 4.0 ± 0.844
1.182LysMet: 1.182 ± 0.399
2.455LysAsn: 2.455 ± 0.35
1.818LysPro: 1.818 ± 0.565
1.909LysGln: 1.909 ± 0.521
3.364LysArg: 3.364 ± 0.763
2.455LysSer: 2.455 ± 0.432
2.364LysThr: 2.364 ± 0.649
2.455LysVal: 2.455 ± 0.553
0.545LysTrp: 0.545 ± 0.176
1.273LysTyr: 1.273 ± 0.368
0.0LysXaa: 0.0 ± 0.0
Leu
7.0LeuAla: 7.0 ± 1.08
1.545LeuCys: 1.545 ± 0.41
4.909LeuAsp: 4.909 ± 0.69
5.364LeuGlu: 5.364 ± 1.2
3.091LeuPhe: 3.091 ± 0.52
4.909LeuGly: 4.909 ± 0.72
4.0LeuHis: 4.0 ± 0.711
2.727LeuIle: 2.727 ± 0.431
4.364LeuLys: 4.364 ± 0.849
10.091LeuLeu: 10.091 ± 1.109
3.091LeuMet: 3.091 ± 0.544
4.636LeuAsn: 4.636 ± 0.589
5.909LeuPro: 5.909 ± 0.809
5.545LeuGln: 5.545 ± 0.562
6.636LeuArg: 6.636 ± 0.82
6.182LeuSer: 6.182 ± 0.647
6.636LeuThr: 6.636 ± 0.859
6.727LeuVal: 6.727 ± 0.894
1.727LeuTrp: 1.727 ± 0.335
2.636LeuTyr: 2.636 ± 0.54
0.0LeuXaa: 0.0 ± 0.0
Met
2.636MetAla: 2.636 ± 0.445
0.636MetCys: 0.636 ± 0.231
2.182MetAsp: 2.182 ± 0.36
1.545MetGlu: 1.545 ± 0.377
0.545MetPhe: 0.545 ± 0.204
1.636MetGly: 1.636 ± 0.361
0.636MetHis: 0.636 ± 0.268
1.364MetIle: 1.364 ± 0.321
0.909MetLys: 0.909 ± 0.288
2.273MetLeu: 2.273 ± 0.441
0.455MetMet: 0.455 ± 0.18
1.091MetAsn: 1.091 ± 0.353
2.0MetPro: 2.0 ± 0.445
1.364MetGln: 1.364 ± 0.363
1.636MetArg: 1.636 ± 0.441
2.091MetSer: 2.091 ± 0.37
1.455MetThr: 1.455 ± 0.285
1.273MetVal: 1.273 ± 0.357
0.364MetTrp: 0.364 ± 0.194
1.182MetTyr: 1.182 ± 0.266
0.0MetXaa: 0.0 ± 0.0
Asn
2.545AsnAla: 2.545 ± 0.6
0.545AsnCys: 0.545 ± 0.266
3.273AsnAsp: 3.273 ± 0.65
2.0AsnGlu: 2.0 ± 0.453
2.818AsnPhe: 2.818 ± 0.547
2.727AsnGly: 2.727 ± 0.552
1.364AsnHis: 1.364 ± 0.396
3.0AsnIle: 3.0 ± 0.59
1.909AsnLys: 1.909 ± 0.459
5.182AsnLeu: 5.182 ± 0.836
2.0AsnMet: 2.0 ± 0.539
1.909AsnAsn: 1.909 ± 0.57
3.0AsnPro: 3.0 ± 0.493
1.727AsnGln: 1.727 ± 0.472
2.818AsnArg: 2.818 ± 0.462
2.727AsnSer: 2.727 ± 0.433
2.091AsnThr: 2.091 ± 0.527
3.182AsnVal: 3.182 ± 0.673
1.0AsnTrp: 1.0 ± 0.261
2.273AsnTyr: 2.273 ± 0.369
0.0AsnXaa: 0.0 ± 0.0
Pro
4.636ProAla: 4.636 ± 0.677
0.909ProCys: 0.909 ± 0.302
3.545ProAsp: 3.545 ± 0.608
3.545ProGlu: 3.545 ± 0.716
3.0ProPhe: 3.0 ± 0.559
4.0ProGly: 4.0 ± 0.518
1.364ProHis: 1.364 ± 0.321
2.091ProIle: 2.091 ± 0.403
2.182ProLys: 2.182 ± 0.503
4.727ProLeu: 4.727 ± 0.801
1.273ProMet: 1.273 ± 0.394
2.818ProAsn: 2.818 ± 0.524
7.0ProPro: 7.0 ± 1.448
2.727ProGln: 2.727 ± 0.556
5.0ProArg: 5.0 ± 0.677
5.182ProSer: 5.182 ± 0.896
4.455ProThr: 4.455 ± 0.777
4.273ProVal: 4.273 ± 0.572
0.545ProTrp: 0.545 ± 0.26
1.727ProTyr: 1.727 ± 0.421
0.0ProXaa: 0.0 ± 0.0
Gln
3.727GlnAla: 3.727 ± 0.583
1.0GlnCys: 1.0 ± 0.285
2.636GlnAsp: 2.636 ± 0.432
3.909GlnGlu: 3.909 ± 0.682
1.273GlnPhe: 1.273 ± 0.355
2.182GlnGly: 2.182 ± 0.373
1.273GlnHis: 1.273 ± 0.33
1.727GlnIle: 1.727 ± 0.357
1.818GlnLys: 1.818 ± 0.449
3.636GlnLeu: 3.636 ± 0.602
1.0GlnMet: 1.0 ± 0.265
2.545GlnAsn: 2.545 ± 0.71
3.636GlnPro: 3.636 ± 0.46
3.091GlnGln: 3.091 ± 0.618
2.818GlnArg: 2.818 ± 0.43
3.091GlnSer: 3.091 ± 0.564
2.364GlnThr: 2.364 ± 0.419
2.273GlnVal: 2.273 ± 0.447
0.273GlnTrp: 0.273 ± 0.181
0.636GlnTyr: 0.636 ± 0.217
0.0GlnXaa: 0.0 ± 0.0
Arg
7.0ArgAla: 7.0 ± 1.199
1.455ArgCys: 1.455 ± 0.305
3.182ArgAsp: 3.182 ± 0.842
3.545ArgGlu: 3.545 ± 0.634
2.0ArgPhe: 2.0 ± 0.453
4.818ArgGly: 4.818 ± 0.564
1.818ArgHis: 1.818 ± 0.451
2.273ArgIle: 2.273 ± 0.275
2.455ArgLys: 2.455 ± 0.465
5.273ArgLeu: 5.273 ± 0.963
1.455ArgMet: 1.455 ± 0.319
3.727ArgAsn: 3.727 ± 0.521
5.182ArgPro: 5.182 ± 0.796
3.364ArgGln: 3.364 ± 0.673
9.364ArgArg: 9.364 ± 2.191
3.636ArgSer: 3.636 ± 0.757
3.545ArgThr: 3.545 ± 0.662
4.636ArgVal: 4.636 ± 0.871
1.273ArgTrp: 1.273 ± 0.24
2.364ArgTyr: 2.364 ± 0.465
0.0ArgXaa: 0.0 ± 0.0
Ser
3.636SerAla: 3.636 ± 0.689
1.091SerCys: 1.091 ± 0.363
2.364SerAsp: 2.364 ± 0.535
3.455SerGlu: 3.455 ± 0.647
2.818SerPhe: 2.818 ± 0.483
5.182SerGly: 5.182 ± 0.826
1.727SerHis: 1.727 ± 0.492
2.818SerIle: 2.818 ± 0.589
1.818SerLys: 1.818 ± 0.429
6.636SerLeu: 6.636 ± 0.545
1.818SerMet: 1.818 ± 0.54
1.909SerAsn: 1.909 ± 0.417
3.636SerPro: 3.636 ± 0.754
2.909SerGln: 2.909 ± 0.571
4.091SerArg: 4.091 ± 0.58
6.091SerSer: 6.091 ± 1.049
4.273SerThr: 4.273 ± 0.694
4.273SerVal: 4.273 ± 0.571
0.727SerTrp: 0.727 ± 0.253
2.364SerTyr: 2.364 ± 0.447
0.0SerXaa: 0.0 ± 0.0
Thr
3.0ThrAla: 3.0 ± 0.735
1.455ThrCys: 1.455 ± 0.387
1.818ThrAsp: 1.818 ± 0.444
2.545ThrGlu: 2.545 ± 0.452
2.909ThrPhe: 2.909 ± 0.594
3.909ThrGly: 3.909 ± 0.686
1.182ThrHis: 1.182 ± 0.272
2.455ThrIle: 2.455 ± 0.558
2.636ThrLys: 2.636 ± 0.698
8.182ThrLeu: 8.182 ± 0.973
1.091ThrMet: 1.091 ± 0.282
3.091ThrAsn: 3.091 ± 0.669
4.364ThrPro: 4.364 ± 0.712
2.273ThrGln: 2.273 ± 0.404
3.455ThrArg: 3.455 ± 0.624
3.0ThrSer: 3.0 ± 0.499
4.455ThrThr: 4.455 ± 1.001
4.636ThrVal: 4.636 ± 0.585
1.0ThrTrp: 1.0 ± 0.287
2.727ThrTyr: 2.727 ± 0.551
0.0ThrXaa: 0.0 ± 0.0
Val
4.455ValAla: 4.455 ± 0.649
1.273ValCys: 1.273 ± 0.476
4.0ValAsp: 4.0 ± 0.794
3.636ValGlu: 3.636 ± 0.645
2.364ValPhe: 2.364 ± 0.461
3.364ValGly: 3.364 ± 0.569
0.636ValHis: 0.636 ± 0.232
2.727ValIle: 2.727 ± 0.418
2.091ValLys: 2.091 ± 0.739
5.818ValLeu: 5.818 ± 0.608
1.909ValMet: 1.909 ± 0.384
3.909ValAsn: 3.909 ± 0.613
4.091ValPro: 4.091 ± 0.585
3.091ValGln: 3.091 ± 0.588
5.364ValArg: 5.364 ± 0.88
3.818ValSer: 3.818 ± 0.504
4.182ValThr: 4.182 ± 0.724
4.455ValVal: 4.455 ± 0.843
0.818ValTrp: 0.818 ± 0.23
2.727ValTyr: 2.727 ± 0.543
0.0ValXaa: 0.0 ± 0.0
Trp
0.545TrpAla: 0.545 ± 0.235
0.182TrpCys: 0.182 ± 0.126
0.909TrpAsp: 0.909 ± 0.308
1.091TrpGlu: 1.091 ± 0.293
0.636TrpPhe: 0.636 ± 0.232
0.909TrpGly: 0.909 ± 0.289
0.091TrpHis: 0.091 ± 0.098
0.364TrpIle: 0.364 ± 0.175
0.909TrpLys: 0.909 ± 0.317
1.0TrpLeu: 1.0 ± 0.222
0.818TrpMet: 0.818 ± 0.291
1.0TrpAsn: 1.0 ± 0.398
0.636TrpPro: 0.636 ± 0.215
0.818TrpGln: 0.818 ± 0.257
0.455TrpArg: 0.455 ± 0.232
1.182TrpSer: 1.182 ± 0.261
0.909TrpThr: 0.909 ± 0.357
0.182TrpVal: 0.182 ± 0.135
0.091TrpTrp: 0.091 ± 0.083
0.545TrpTyr: 0.545 ± 0.343
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.091TyrAla: 2.091 ± 0.539
0.636TyrCys: 0.636 ± 0.312
2.091TyrAsp: 2.091 ± 0.504
2.0TyrGlu: 2.0 ± 0.436
1.727TyrPhe: 1.727 ± 0.473
2.091TyrGly: 2.091 ± 0.491
1.182TyrHis: 1.182 ± 0.298
1.091TyrIle: 1.091 ± 0.23
2.091TyrLys: 2.091 ± 0.433
3.818TyrLeu: 3.818 ± 0.623
1.273TyrMet: 1.273 ± 0.299
1.455TyrAsn: 1.455 ± 0.482
1.818TyrPro: 1.818 ± 0.418
1.455TyrGln: 1.455 ± 0.343
2.455TyrArg: 2.455 ± 0.447
1.909TyrSer: 1.909 ± 0.471
2.091TyrThr: 2.091 ± 0.349
1.636TyrVal: 1.636 ± 0.329
0.455TyrTrp: 0.455 ± 0.198
0.727TyrTyr: 0.727 ± 0.308
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 36 proteins (11001 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski