Amino acid dipepetide frequency for Wenling crustacean virus 12

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.591AlaAla: 6.591 ± 2.83
1.318AlaCys: 1.318 ± 0.7
0.879AlaAsp: 0.879 ± 0.704
3.515AlaGlu: 3.515 ± 1.007
2.197AlaPhe: 2.197 ± 0.543
4.394AlaGly: 4.394 ± 0.955
0.879AlaHis: 0.879 ± 0.466
5.712AlaIle: 5.712 ± 1.5
6.151AlaLys: 6.151 ± 0.929
9.227AlaLeu: 9.227 ± 2.52
2.197AlaMet: 2.197 ± 2.282
2.197AlaAsn: 2.197 ± 3.019
3.515AlaPro: 3.515 ± 4.652
3.515AlaGln: 3.515 ± 1.817
4.833AlaArg: 4.833 ± 1.54
5.272AlaSer: 5.272 ± 5.953
3.954AlaThr: 3.954 ± 1.698
4.394AlaVal: 4.394 ± 0.853
0.879AlaTrp: 0.879 ± 0.704
3.515AlaTyr: 3.515 ± 1.036
0.0AlaXaa: 0.0 ± 0.0
Cys
2.197CysAla: 2.197 ± 0.543
0.439CysCys: 0.439 ± 0.233
0.0CysAsp: 0.0 ± 0.0
0.439CysGlu: 0.439 ± 0.233
0.879CysPhe: 0.879 ± 0.704
0.439CysGly: 0.439 ± 0.233
0.879CysHis: 0.879 ± 0.466
0.879CysIle: 0.879 ± 0.466
0.879CysLys: 0.879 ± 0.704
0.879CysLeu: 0.879 ± 0.466
0.879CysMet: 0.879 ± 0.704
0.879CysAsn: 0.879 ± 0.466
1.757CysPro: 1.757 ± 0.933
0.0CysGln: 0.0 ± 0.0
0.439CysArg: 0.439 ± 0.233
3.076CysSer: 3.076 ± 1.632
0.879CysThr: 0.879 ± 0.466
0.439CysVal: 0.439 ± 0.233
0.0CysTrp: 0.0 ± 0.0
0.439CysTyr: 0.439 ± 0.233
0.0CysXaa: 0.0 ± 0.0
Asp
2.636AspAla: 2.636 ± 1.132
0.439AspCys: 0.439 ± 0.233
1.318AspAsp: 1.318 ± 0.7
2.636AspGlu: 2.636 ± 1.132
1.318AspPhe: 1.318 ± 0.7
3.076AspGly: 3.076 ± 1.046
0.439AspHis: 0.439 ± 0.883
3.515AspIle: 3.515 ± 1.036
1.757AspLys: 1.757 ± 0.933
4.833AspLeu: 4.833 ± 1.54
0.439AspMet: 0.439 ± 0.233
3.954AspAsn: 3.954 ± 0.865
3.515AspPro: 3.515 ± 1.036
0.439AspGln: 0.439 ± 0.233
2.197AspArg: 2.197 ± 1.166
2.197AspSer: 2.197 ± 0.543
7.03AspThr: 7.03 ± 0.617
4.394AspVal: 4.394 ± 0.955
1.318AspTrp: 1.318 ± 1.481
2.197AspTyr: 2.197 ± 1.256
0.0AspXaa: 0.0 ± 0.0
Glu
3.515GluAla: 3.515 ± 2.32
1.757GluCys: 1.757 ± 0.503
4.394GluAsp: 4.394 ± 1.462
3.076GluGlu: 3.076 ± 1.392
1.318GluPhe: 1.318 ± 0.7
1.318GluGly: 1.318 ± 0.7
0.879GluHis: 0.879 ± 0.704
1.757GluIle: 1.757 ± 2.462
1.318GluLys: 1.318 ± 0.7
7.469GluLeu: 7.469 ± 0.82
1.318GluMet: 1.318 ± 0.566
2.636GluAsn: 2.636 ± 1.211
1.757GluPro: 1.757 ± 0.503
2.197GluGln: 2.197 ± 1.256
4.833GluArg: 4.833 ± 1.85
5.272GluSer: 5.272 ± 4.112
1.757GluThr: 1.757 ± 0.933
4.833GluVal: 4.833 ± 1.195
1.318GluTrp: 1.318 ± 0.7
3.076GluTyr: 3.076 ± 0.84
0.0GluXaa: 0.0 ± 0.0
Phe
1.318PheAla: 1.318 ± 0.566
0.439PheCys: 0.439 ± 0.233
1.757PheAsp: 1.757 ± 0.933
3.076PheGlu: 3.076 ± 1.046
0.0PhePhe: 0.0 ± 0.0
1.757PheGly: 1.757 ± 0.503
0.0PheHis: 0.0 ± 0.0
0.439PheIle: 0.439 ± 0.883
2.636PheLys: 2.636 ± 3.161
0.879PheLeu: 0.879 ± 0.466
0.439PheMet: 0.439 ± 0.233
0.439PheAsn: 0.439 ± 1.724
0.879PhePro: 0.879 ± 0.466
1.318PheGln: 1.318 ± 0.7
1.757PheArg: 1.757 ± 0.503
1.757PheSer: 1.757 ± 0.933
1.757PheThr: 1.757 ± 0.503
0.879PheVal: 0.879 ± 0.466
0.439PheTrp: 0.439 ± 0.233
0.0PheTyr: 0.0 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
3.954GlyAla: 3.954 ± 1.698
1.318GlyCys: 1.318 ± 0.7
2.197GlyAsp: 2.197 ± 0.543
5.712GlyGlu: 5.712 ± 3.032
1.757GlyPhe: 1.757 ± 1.577
3.954GlyGly: 3.954 ± 2.099
0.879GlyHis: 0.879 ± 0.704
2.636GlyIle: 2.636 ± 2.113
3.076GlyLys: 3.076 ± 0.84
8.348GlyLeu: 8.348 ± 2.706
1.318GlyMet: 1.318 ± 0.566
2.197GlyAsn: 2.197 ± 1.166
5.712GlyPro: 5.712 ± 2.739
1.318GlyGln: 1.318 ± 0.7
2.197GlyArg: 2.197 ± 1.256
3.954GlySer: 3.954 ± 1.245
3.076GlyThr: 3.076 ± 1.626
1.318GlyVal: 1.318 ± 3.308
0.439GlyTrp: 0.439 ± 0.233
4.394GlyTyr: 4.394 ± 1.087
0.0GlyXaa: 0.0 ± 0.0
His
3.076HisAla: 3.076 ± 3.354
0.439HisCys: 0.439 ± 0.883
0.879HisAsp: 0.879 ± 1.59
0.0HisGlu: 0.0 ± 0.0
0.0HisPhe: 0.0 ± 0.0
0.439HisGly: 0.439 ± 0.883
0.439HisHis: 0.439 ± 0.233
2.636HisIle: 2.636 ± 1.399
1.757HisLys: 1.757 ± 2.315
2.197HisLeu: 2.197 ± 0.543
0.879HisMet: 0.879 ± 0.466
1.318HisAsn: 1.318 ± 0.7
2.197HisPro: 2.197 ± 0.543
2.636HisGln: 2.636 ± 1.132
2.197HisArg: 2.197 ± 0.543
0.879HisSer: 0.879 ± 0.466
2.197HisThr: 2.197 ± 1.166
0.879HisVal: 0.879 ± 0.466
0.0HisTrp: 0.0 ± 0.0
1.757HisTyr: 1.757 ± 0.933
0.0HisXaa: 0.0 ± 0.0
Ile
3.954IleAla: 3.954 ± 1.021
0.439IleCys: 0.439 ± 0.233
1.757IleAsp: 1.757 ± 0.933
3.515IleGlu: 3.515 ± 1.036
1.318IlePhe: 1.318 ± 0.7
5.272IleGly: 5.272 ± 0.547
3.515IleHis: 3.515 ± 1.399
2.197IleIle: 2.197 ± 0.543
3.515IleLys: 3.515 ± 1.036
6.591IleLeu: 6.591 ± 2.579
1.757IleMet: 1.757 ± 0.933
4.394IleAsn: 4.394 ± 2.773
2.197IlePro: 2.197 ± 1.256
0.439IleGln: 0.439 ± 0.233
3.515IleArg: 3.515 ± 0.938
4.394IleSer: 4.394 ± 1.087
6.151IleThr: 6.151 ± 1.557
4.833IleVal: 4.833 ± 1.54
0.439IleTrp: 0.439 ± 0.233
1.757IleTyr: 1.757 ± 0.933
0.0IleXaa: 0.0 ± 0.0
Lys
4.833LysAla: 4.833 ± 0.742
0.439LysCys: 0.439 ± 0.233
3.076LysAsp: 3.076 ± 1.956
3.954LysGlu: 3.954 ± 1.021
0.879LysPhe: 0.879 ± 0.466
2.197LysGly: 2.197 ± 1.166
1.757LysHis: 1.757 ± 0.503
4.394LysIle: 4.394 ± 1.7
1.318LysLys: 1.318 ± 0.7
5.712LysLeu: 5.712 ± 4.0
0.0LysMet: 0.0 ± 0.0
1.318LysAsn: 1.318 ± 0.566
1.318LysPro: 1.318 ± 0.7
1.318LysGln: 1.318 ± 1.481
4.394LysArg: 4.394 ± 4.169
3.515LysSer: 3.515 ± 2.817
2.197LysThr: 2.197 ± 1.166
3.954LysVal: 3.954 ± 2.099
1.318LysTrp: 1.318 ± 0.7
1.318LysTyr: 1.318 ± 0.7
0.0LysXaa: 0.0 ± 0.0
Leu
9.227LeuAla: 9.227 ± 2.574
1.757LeuCys: 1.757 ± 0.933
7.469LeuAsp: 7.469 ± 2.648
7.03LeuGlu: 7.03 ± 4.061
1.757LeuPhe: 1.757 ± 0.503
5.712LeuGly: 5.712 ± 1.147
2.197LeuHis: 2.197 ± 1.166
4.394LeuIle: 4.394 ± 1.087
7.469LeuLys: 7.469 ± 3.964
11.424LeuLeu: 11.424 ± 4.523
2.636LeuMet: 2.636 ± 1.997
1.757LeuAsn: 1.757 ± 0.503
7.469LeuPro: 7.469 ± 0.82
3.954LeuGln: 3.954 ± 2.752
4.833LeuArg: 4.833 ± 1.683
7.909LeuSer: 7.909 ± 1.73
7.909LeuThr: 7.909 ± 1.15
5.712LeuVal: 5.712 ± 1.5
0.879LeuTrp: 0.879 ± 0.466
5.272LeuTyr: 5.272 ± 1.51
0.0LeuXaa: 0.0 ± 0.0
Met
0.879MetAla: 0.879 ± 1.986
0.879MetCys: 0.879 ± 0.466
0.439MetAsp: 0.439 ± 0.233
2.636MetGlu: 2.636 ± 2.113
1.318MetPhe: 1.318 ± 0.7
1.757MetGly: 1.757 ± 1.577
0.879MetHis: 0.879 ± 0.466
0.879MetIle: 0.879 ± 0.466
1.318MetLys: 1.318 ± 0.566
1.318MetLeu: 1.318 ± 0.566
1.318MetMet: 1.318 ± 0.7
0.439MetAsn: 0.439 ± 0.233
1.757MetPro: 1.757 ± 0.503
0.439MetGln: 0.439 ± 0.233
0.879MetArg: 0.879 ± 0.466
2.636MetSer: 2.636 ± 1.132
1.757MetThr: 1.757 ± 0.503
0.879MetVal: 0.879 ± 0.466
0.439MetTrp: 0.439 ± 0.233
0.879MetTyr: 0.879 ± 0.466
0.0MetXaa: 0.0 ± 0.0
Asn
1.318AsnAla: 1.318 ± 1.778
0.439AsnCys: 0.439 ± 0.233
1.318AsnAsp: 1.318 ± 0.566
1.757AsnGlu: 1.757 ± 1.408
0.0AsnPhe: 0.0 ± 0.0
0.879AsnGly: 0.879 ± 0.466
1.318AsnHis: 1.318 ± 0.566
4.394AsnIle: 4.394 ± 1.7
1.318AsnLys: 1.318 ± 1.481
6.591AsnLeu: 6.591 ± 0.7
0.439AsnMet: 0.439 ± 0.233
0.439AsnAsn: 0.439 ± 0.233
2.636AsnPro: 2.636 ± 0.668
2.636AsnGln: 2.636 ± 3.088
0.439AsnArg: 0.439 ± 0.233
2.197AsnSer: 2.197 ± 1.387
2.197AsnThr: 2.197 ± 0.543
3.076AsnVal: 3.076 ± 1.046
0.439AsnTrp: 0.439 ± 0.233
3.954AsnTyr: 3.954 ± 1.021
0.0AsnXaa: 0.0 ± 0.0
Pro
4.833ProAla: 4.833 ± 1.623
1.318ProCys: 1.318 ± 0.7
3.076ProAsp: 3.076 ± 1.057
1.318ProGlu: 1.318 ± 1.581
0.439ProPhe: 0.439 ± 0.233
4.394ProGly: 4.394 ± 1.087
2.636ProHis: 2.636 ± 1.211
3.515ProIle: 3.515 ± 1.036
2.636ProLys: 2.636 ± 1.211
5.712ProLeu: 5.712 ± 1.147
0.0ProMet: 0.0 ± 0.0
1.757ProAsn: 1.757 ± 0.933
5.712ProPro: 5.712 ± 2.209
1.318ProGln: 1.318 ± 0.7
3.954ProArg: 3.954 ± 0.865
4.833ProSer: 4.833 ± 2.418
2.197ProThr: 2.197 ± 1.387
4.394ProVal: 4.394 ± 2.719
1.318ProTrp: 1.318 ± 0.7
1.757ProTyr: 1.757 ± 0.503
0.0ProXaa: 0.0 ± 0.0
Gln
1.757GlnAla: 1.757 ± 0.933
0.0GlnCys: 0.0 ± 0.0
1.757GlnAsp: 1.757 ± 0.503
2.197GlnGlu: 2.197 ± 1.359
0.439GlnPhe: 0.439 ± 0.883
1.757GlnGly: 1.757 ± 1.577
1.757GlnHis: 1.757 ± 3.18
1.757GlnIle: 1.757 ± 1.577
2.197GlnLys: 2.197 ± 0.543
4.833GlnLeu: 4.833 ± 1.54
1.318GlnMet: 1.318 ± 0.7
0.879GlnAsn: 0.879 ± 0.466
3.076GlnPro: 3.076 ± 1.626
1.757GlnGln: 1.757 ± 1.577
2.197GlnArg: 2.197 ± 1.166
2.197GlnSer: 2.197 ± 1.166
2.636GlnThr: 2.636 ± 1.855
1.757GlnVal: 1.757 ± 1.402
0.439GlnTrp: 0.439 ± 0.233
2.197GlnTyr: 2.197 ± 1.166
0.0GlnXaa: 0.0 ± 0.0
Arg
4.394ArgAla: 4.394 ± 1.462
1.318ArgCys: 1.318 ± 0.566
3.515ArgAsp: 3.515 ± 1.007
4.833ArgGlu: 4.833 ± 1.54
0.879ArgPhe: 0.879 ± 1.767
5.272ArgGly: 5.272 ± 1.906
0.879ArgHis: 0.879 ± 0.704
4.833ArgIle: 4.833 ± 0.902
3.515ArgLys: 3.515 ± 4.652
4.394ArgLeu: 4.394 ± 1.462
1.318ArgMet: 1.318 ± 0.7
1.318ArgAsn: 1.318 ± 0.7
1.757ArgPro: 1.757 ± 1.402
0.879ArgGln: 0.879 ± 0.466
3.515ArgArg: 3.515 ± 1.007
3.076ArgSer: 3.076 ± 1.046
2.197ArgThr: 2.197 ± 1.166
5.272ArgVal: 5.272 ± 1.005
0.439ArgTrp: 0.439 ± 0.233
3.076ArgTyr: 3.076 ± 1.046
0.0ArgXaa: 0.0 ± 0.0
Ser
3.954SerAla: 3.954 ± 1.698
0.439SerCys: 0.439 ± 0.883
2.636SerAsp: 2.636 ± 0.668
2.636SerGlu: 2.636 ± 1.211
0.879SerPhe: 0.879 ± 0.704
3.076SerGly: 3.076 ± 1.046
1.757SerHis: 1.757 ± 0.933
5.272SerIle: 5.272 ± 2.332
2.197SerLys: 2.197 ± 1.166
7.03SerLeu: 7.03 ± 2.209
3.076SerMet: 3.076 ± 1.392
4.394SerAsn: 4.394 ± 1.462
1.757SerPro: 1.757 ± 1.402
3.954SerGln: 3.954 ± 4.817
3.954SerArg: 3.954 ± 1.57
7.469SerSer: 7.469 ± 2.238
5.712SerThr: 5.712 ± 2.261
3.076SerVal: 3.076 ± 0.84
1.318SerTrp: 1.318 ± 0.7
4.394SerTyr: 4.394 ± 1.604
0.0SerXaa: 0.0 ± 0.0
Thr
7.469ThrAla: 7.469 ± 2.431
1.318ThrCys: 1.318 ± 0.7
4.394ThrAsp: 4.394 ± 1.087
2.197ThrGlu: 2.197 ± 1.359
2.636ThrPhe: 2.636 ± 0.668
3.515ThrGly: 3.515 ± 0.938
1.318ThrHis: 1.318 ± 0.566
3.954ThrIle: 3.954 ± 1.021
1.757ThrLys: 1.757 ± 0.503
9.227ThrLeu: 9.227 ± 4.937
2.197ThrMet: 2.197 ± 0.543
3.515ThrAsn: 3.515 ± 3.862
3.954ThrPro: 3.954 ± 2.961
1.757ThrGln: 1.757 ± 0.503
4.394ThrArg: 4.394 ± 1.462
2.197ThrSer: 2.197 ± 1.256
6.591ThrThr: 6.591 ± 0.444
6.151ThrVal: 6.151 ± 2.359
0.439ThrTrp: 0.439 ± 0.233
1.757ThrTyr: 1.757 ± 1.402
0.0ThrXaa: 0.0 ± 0.0
Val
7.03ValAla: 7.03 ± 0.617
0.879ValCys: 0.879 ± 0.466
3.954ValAsp: 3.954 ± 1.57
2.197ValGlu: 2.197 ± 1.166
1.757ValPhe: 1.757 ± 0.503
6.591ValGly: 6.591 ± 1.872
0.439ValHis: 0.439 ± 0.233
3.954ValIle: 3.954 ± 1.245
1.757ValLys: 1.757 ± 1.402
3.515ValLeu: 3.515 ± 1.866
1.318ValMet: 1.318 ± 0.566
3.515ValAsn: 3.515 ± 0.938
3.076ValPro: 3.076 ± 0.84
2.197ValGln: 2.197 ± 1.166
3.515ValArg: 3.515 ± 1.817
3.515ValSer: 3.515 ± 1.465
6.151ValThr: 6.151 ± 4.925
3.954ValVal: 3.954 ± 2.659
1.757ValTrp: 1.757 ± 0.933
2.636ValTyr: 2.636 ± 1.399
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.879TrpCys: 0.879 ± 0.466
1.757TrpAsp: 1.757 ± 1.577
0.439TrpGlu: 0.439 ± 0.233
0.439TrpPhe: 0.439 ± 0.233
0.879TrpGly: 0.879 ± 0.466
0.879TrpHis: 0.879 ± 0.466
0.439TrpIle: 0.439 ± 0.233
0.879TrpLys: 0.879 ± 0.466
1.757TrpLeu: 1.757 ± 0.933
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
0.879TrpPro: 0.879 ± 0.466
0.0TrpGln: 0.0 ± 0.0
0.879TrpArg: 0.879 ± 0.466
0.439TrpSer: 0.439 ± 0.233
1.318TrpThr: 1.318 ± 0.7
1.318TrpVal: 1.318 ± 0.7
0.0TrpTrp: 0.0 ± 0.0
0.439TrpTyr: 0.439 ± 0.233
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.197TyrAla: 2.197 ± 0.543
0.439TyrCys: 0.439 ± 0.233
3.076TyrAsp: 3.076 ± 1.632
2.636TyrGlu: 2.636 ± 1.356
1.757TyrPhe: 1.757 ± 0.503
3.076TyrGly: 3.076 ± 0.84
3.076TyrHis: 3.076 ± 0.84
4.394TyrIle: 4.394 ± 1.087
1.757TyrLys: 1.757 ± 0.503
5.272TyrLeu: 5.272 ± 2.264
0.439TyrMet: 0.439 ± 0.203
0.439TyrAsn: 0.439 ± 0.233
2.197TyrPro: 2.197 ± 0.543
4.833TyrGln: 4.833 ± 1.683
1.757TyrArg: 1.757 ± 0.503
2.197TyrSer: 2.197 ± 1.166
3.076TyrThr: 3.076 ± 1.046
2.197TyrVal: 2.197 ± 0.543
0.0TyrTrp: 0.0 ± 0.0
2.197TyrTyr: 2.197 ± 0.543
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (2277 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski