Amino acid dipepetide frequency for Candidatus Electronema sp. GS

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	13.068AlaAla: 13.068 ± 0.2	1.195AlaCys: 1.195 ± 0.041	5.456AlaAsp: 5.456 ± 0.094	7.721AlaGlu: 7.721 ± 0.122	3.287AlaPhe: 3.287 ± 0.069	7.371AlaGly: 7.371 ± 0.107	1.611AlaHis: 1.611 ± 0.048	4.539AlaIle: 4.539 ± 0.068	4.711AlaLys: 4.711 ± 0.085	9.689AlaLeu: 9.689 ± 0.129	2.468AlaMet: 2.468 ± 0.06	2.603AlaAsn: 2.603 ± 0.054	3.07AlaPro: 3.07 ± 0.062	3.647AlaGln: 3.647 ± 0.095	4.366AlaArg: 4.366 ± 0.083	4.668AlaSer: 4.668 ± 0.08	3.943AlaThr: 3.943 ± 0.085	8.206AlaVal: 8.206 ± 0.131	1.061AlaTrp: 1.061 ± 0.037	2.102AlaTyr: 2.102 ± 0.065	0.0AlaXaa: 0.0 ± 0.0
Cys	1.184CysAla: 1.184 ± 0.037	0.391CysCys: 0.391 ± 0.024	0.607CysAsp: 0.607 ± 0.029	0.737CysGlu: 0.737 ± 0.031	0.606CysPhe: 0.606 ± 0.027	1.441CysGly: 1.441 ± 0.046	0.453CysHis: 0.453 ± 0.033	0.719CysIle: 0.719 ± 0.033	0.586CysLys: 0.586 ± 0.033	1.433CysLeu: 1.433 ± 0.046	0.298CysMet: 0.298 ± 0.018	0.489CysAsn: 0.489 ± 0.026	0.787CysPro: 0.787 ± 0.038	0.508CysGln: 0.508 ± 0.024	1.037CysArg: 1.037 ± 0.039	0.955CysSer: 0.955 ± 0.038	0.724CysThr: 0.724 ± 0.035	0.796CysVal: 0.796 ± 0.033	0.19CysTrp: 0.19 ± 0.014	0.381CysTyr: 0.381 ± 0.024	0.0CysXaa: 0.0 ± 0.0
Asp	4.212AspAla: 4.212 ± 0.079	0.785AspCys: 0.785 ± 0.036	2.575AspAsp: 2.575 ± 0.093	3.63AspGlu: 3.63 ± 0.091	2.488AspPhe: 2.488 ± 0.062	3.76AspGly: 3.76 ± 0.09	0.996AspHis: 0.996 ± 0.033	3.528AspIle: 3.528 ± 0.071	2.973AspLys: 2.973 ± 0.065	5.003AspLeu: 5.003 ± 0.096	1.297AspMet: 1.297 ± 0.041	1.781AspAsn: 1.781 ± 0.053	2.2AspPro: 2.2 ± 0.056	1.743AspGln: 1.743 ± 0.048	2.827AspArg: 2.827 ± 0.062	3.117AspSer: 3.117 ± 0.062	2.257AspThr: 2.257 ± 0.06	3.077AspVal: 3.077 ± 0.065	0.763AspTrp: 0.763 ± 0.03	1.729AspTyr: 1.729 ± 0.048	0.0AspXaa: 0.0 ± 0.0
Glu	6.087GluAla: 6.087 ± 0.108	0.665GluCys: 0.665 ± 0.029	2.923GluAsp: 2.923 ± 0.065	5.142GluGlu: 5.142 ± 0.106	2.203GluPhe: 2.203 ± 0.06	3.882GluGly: 3.882 ± 0.077	1.555GluHis: 1.555 ± 0.049	4.683GluIle: 4.683 ± 0.089	4.524GluLys: 4.524 ± 0.09	7.731GluLeu: 7.731 ± 0.115	1.861GluMet: 1.861 ± 0.043	2.532GluAsn: 2.532 ± 0.057	2.345GluPro: 2.345 ± 0.058	4.443GluGln: 4.443 ± 0.099	4.272GluArg: 4.272 ± 0.085	2.984GluSer: 2.984 ± 0.064	3.255GluThr: 3.255 ± 0.068	4.052GluVal: 4.052 ± 0.075	0.659GluTrp: 0.659 ± 0.027	1.799GluTyr: 1.799 ± 0.05	0.0GluXaa: 0.0 ± 0.0
Phe	3.72PheAla: 3.72 ± 0.077	0.742PheCys: 0.742 ± 0.036	2.298PheAsp: 2.298 ± 0.056	2.031PheGlu: 2.031 ± 0.06	2.398PhePhe: 2.398 ± 0.068	3.01PheGly: 3.01 ± 0.057	0.943PheHis: 0.943 ± 0.033	2.433PheIle: 2.433 ± 0.062	1.775PheLys: 1.775 ± 0.044	4.313PheLeu: 4.313 ± 0.097	0.889PheMet: 0.889 ± 0.039	1.5PheAsn: 1.5 ± 0.044	1.723PhePro: 1.723 ± 0.051	1.379PheGln: 1.379 ± 0.045	2.208PheArg: 2.208 ± 0.053	3.244PheSer: 3.244 ± 0.074	2.199PheThr: 2.199 ± 0.05	2.462PheVal: 2.462 ± 0.06	0.488PheTrp: 0.488 ± 0.026	1.249PheTyr: 1.249 ± 0.04	0.0PheXaa: 0.0 ± 0.0
Gly	5.445GlyAla: 5.445 ± 0.109	1.347GlyCys: 1.347 ± 0.048	3.321GlyAsp: 3.321 ± 0.071	4.376GlyGlu: 4.376 ± 0.073	3.023GlyPhe: 3.023 ± 0.056	5.446GlyGly: 5.446 ± 0.096	1.519GlyHis: 1.519 ± 0.044	5.007GlyIle: 5.007 ± 0.083	4.858GlyLys: 4.858 ± 0.093	7.308GlyLeu: 7.308 ± 0.104	2.074GlyMet: 2.074 ± 0.057	2.547GlyAsn: 2.547 ± 0.063	2.074GlyPro: 2.074 ± 0.057	2.804GlyGln: 2.804 ± 0.066	4.345GlyArg: 4.345 ± 0.079	4.659GlySer: 4.659 ± 0.083	3.856GlyThr: 3.856 ± 0.099	4.434GlyVal: 4.434 ± 0.094	1.007GlyTrp: 1.007 ± 0.04	2.179GlyTyr: 2.179 ± 0.062	0.0GlyXaa: 0.0 ± 0.0
His	1.651HisAla: 1.651 ± 0.05	0.41HisCys: 0.41 ± 0.024	1.163HisAsp: 1.163 ± 0.038	1.384HisGlu: 1.384 ± 0.042	0.958HisPhe: 0.958 ± 0.032	1.639HisGly: 1.639 ± 0.053	0.608HisHis: 0.608 ± 0.034	1.29HisIle: 1.29 ± 0.038	0.885HisLys: 0.885 ± 0.031	2.375HisLeu: 2.375 ± 0.059	0.298HisMet: 0.298 ± 0.019	0.729HisAsn: 0.729 ± 0.036	1.338HisPro: 1.338 ± 0.044	0.888HisGln: 0.888 ± 0.036	1.267HisArg: 1.267 ± 0.044	1.292HisSer: 1.292 ± 0.041	0.844HisThr: 0.844 ± 0.035	1.294HisVal: 1.294 ± 0.04	0.267HisTrp: 0.267 ± 0.018	0.674HisTyr: 0.674 ± 0.027	0.0HisXaa: 0.0 ± 0.0
Ile	5.985IleAla: 5.985 ± 0.096	0.942IleCys: 0.942 ± 0.039	3.373IleAsp: 3.373 ± 0.073	4.133IleGlu: 4.133 ± 0.072	2.537IlePhe: 2.537 ± 0.068	4.658IleGly: 4.658 ± 0.096	1.238IleHis: 1.238 ± 0.037	3.933IleIle: 3.933 ± 0.083	3.23IleLys: 3.23 ± 0.062	5.554IleLeu: 5.554 ± 0.091	1.3IleMet: 1.3 ± 0.041	2.441IleAsn: 2.441 ± 0.062	2.575IlePro: 2.575 ± 0.057	1.894IleGln: 1.894 ± 0.047	3.57IleArg: 3.57 ± 0.071	4.527IleSer: 4.527 ± 0.085	3.375IleThr: 3.375 ± 0.067	3.882IleVal: 3.882 ± 0.081	0.6IleTrp: 0.6 ± 0.035	1.662IleTyr: 1.662 ± 0.047	0.0IleXaa: 0.0 ± 0.0
Lys	4.918LysAla: 4.918 ± 0.097	0.468LysCys: 0.468 ± 0.026	2.66LysAsp: 2.66 ± 0.064	4.406LysGlu: 4.406 ± 0.085	1.621LysPhe: 1.621 ± 0.048	3.619LysGly: 3.619 ± 0.081	1.04LysHis: 1.04 ± 0.042	3.833LysIle: 3.833 ± 0.073	4.27LysLys: 4.27 ± 0.085	4.716LysLeu: 4.716 ± 0.091	1.521LysMet: 1.521 ± 0.048	2.432LysAsn: 2.432 ± 0.065	2.118LysPro: 2.118 ± 0.05	2.438LysGln: 2.438 ± 0.058	2.635LysArg: 2.635 ± 0.068	2.698LysSer: 2.698 ± 0.06	3.036LysThr: 3.036 ± 0.07	3.512LysVal: 3.512 ± 0.068	0.43LysTrp: 0.43 ± 0.027	1.605LysTyr: 1.605 ± 0.048	0.0LysXaa: 0.0 ± 0.0
Leu	10.976LeuAla: 10.976 ± 0.139	1.454LeuCys: 1.454 ± 0.044	5.339LeuAsp: 5.339 ± 0.089	6.265LeuGlu: 6.265 ± 0.091	4.483LeuPhe: 4.483 ± 0.089	6.476LeuGly: 6.476 ± 0.103	2.681LeuHis: 2.681 ± 0.068	6.125LeuIle: 6.125 ± 0.113	5.174LeuLys: 5.174 ± 0.081	12.903LeuLeu: 12.903 ± 0.217	2.239LeuMet: 2.239 ± 0.058	3.698LeuAsn: 3.698 ± 0.08	5.722LeuPro: 5.722 ± 0.103	3.75LeuGln: 3.75 ± 0.081	6.835LeuArg: 6.835 ± 0.121	6.685LeuSer: 6.685 ± 0.109	5.926LeuThr: 5.926 ± 0.094	6.011LeuVal: 6.011 ± 0.098	0.974LeuTrp: 0.974 ± 0.037	2.55LeuTyr: 2.55 ± 0.07	0.0LeuXaa: 0.0 ± 0.0
Met	2.311MetAla: 2.311 ± 0.051	0.192MetCys: 0.192 ± 0.016	1.202MetAsp: 1.202 ± 0.04	1.488MetGlu: 1.488 ± 0.047	0.781MetPhe: 0.781 ± 0.036	1.511MetGly: 1.511 ± 0.05	0.406MetHis: 0.406 ± 0.024	1.527MetIle: 1.527 ± 0.043	1.559MetLys: 1.559 ± 0.039	2.542MetLeu: 2.542 ± 0.066	0.699MetMet: 0.699 ± 0.035	1.253MetAsn: 1.253 ± 0.039	1.328MetPro: 1.328 ± 0.04	1.222MetGln: 1.222 ± 0.041	1.348MetArg: 1.348 ± 0.043	1.517MetSer: 1.517 ± 0.042	1.491MetThr: 1.491 ± 0.041	1.399MetVal: 1.399 ± 0.046	0.151MetTrp: 0.151 ± 0.013	0.509MetTyr: 0.509 ± 0.029	0.0MetXaa: 0.0 ± 0.0
Asn	2.899AsnAla: 2.899 ± 0.068	0.55AsnCys: 0.55 ± 0.028	1.723AsnAsp: 1.723 ± 0.044	2.058AsnGlu: 2.058 ± 0.054	1.446AsnPhe: 1.446 ± 0.049	2.631AsnGly: 2.631 ± 0.073	0.677AsnHis: 0.677 ± 0.032	2.52AsnIle: 2.52 ± 0.073	1.8AsnLys: 1.8 ± 0.057	3.656AsnLeu: 3.656 ± 0.082	0.865AsnMet: 0.865 ± 0.034	1.471AsnAsn: 1.471 ± 0.055	2.051AsnPro: 2.051 ± 0.058	1.467AsnGln: 1.467 ± 0.042	2.15AsnArg: 2.15 ± 0.052	2.304AsnSer: 2.304 ± 0.054	1.665AsnThr: 1.665 ± 0.049	2.119AsnVal: 2.119 ± 0.057	0.413AsnTrp: 0.413 ± 0.024	1.066AsnTyr: 1.066 ± 0.038	0.0AsnXaa: 0.0 ± 0.0
Pro	4.318ProAla: 4.318 ± 0.082	0.524ProCys: 0.524 ± 0.033	3.0ProAsp: 3.0 ± 0.063	3.794ProGlu: 3.794 ± 0.069	1.831ProPhe: 1.831 ± 0.047	2.986ProGly: 2.986 ± 0.066	0.894ProHis: 0.894 ± 0.03	1.935ProIle: 1.935 ± 0.055	2.012ProLys: 2.012 ± 0.053	4.516ProLeu: 4.516 ± 0.099	0.965ProMet: 0.965 ± 0.035	1.295ProAsn: 1.295 ± 0.041	2.201ProPro: 2.201 ± 0.082	1.752ProGln: 1.752 ± 0.047	1.584ProArg: 1.584 ± 0.048	2.357ProSer: 2.357 ± 0.055	1.924ProThr: 1.924 ± 0.052	3.65ProVal: 3.65 ± 0.072	0.57ProTrp: 0.57 ± 0.03	1.151ProTyr: 1.151 ± 0.038	0.0ProXaa: 0.0 ± 0.0
Gln	4.381GlnAla: 4.381 ± 0.088	0.505GlnCys: 0.505 ± 0.027	1.769GlnAsp: 1.769 ± 0.048	3.318GlnGlu: 3.318 ± 0.082	1.435GlnPhe: 1.435 ± 0.046	3.061GlnGly: 3.061 ± 0.066	1.13GlnHis: 1.13 ± 0.039	2.407GlnIle: 2.407 ± 0.059	2.077GlnLys: 2.077 ± 0.06	4.592GlnLeu: 4.592 ± 0.092	1.044GlnMet: 1.044 ± 0.037	1.3GlnAsn: 1.3 ± 0.043	1.971GlnPro: 1.971 ± 0.051	2.746GlnGln: 2.746 ± 0.087	2.506GlnArg: 2.506 ± 0.068	2.083GlnSer: 2.083 ± 0.053	1.909GlnThr: 1.909 ± 0.057	2.679GlnVal: 2.679 ± 0.062	0.423GlnTrp: 0.423 ± 0.025	1.06GlnTyr: 1.06 ± 0.04	0.0GlnXaa: 0.0 ± 0.0
Arg	4.115ArgAla: 4.115 ± 0.074	0.884ArgCys: 0.884 ± 0.036	2.647ArgAsp: 2.647 ± 0.063	3.905ArgGlu: 3.905 ± 0.081	2.516ArgPhe: 2.516 ± 0.06	2.917ArgGly: 2.917 ± 0.057	1.338ArgHis: 1.338 ± 0.041	4.053ArgIle: 4.053 ± 0.077	3.363ArgLys: 3.363 ± 0.071	6.44ArgLeu: 6.44 ± 0.108	1.608ArgMet: 1.608 ± 0.05	2.078ArgAsn: 2.078 ± 0.051	2.247ArgPro: 2.247 ± 0.055	3.209ArgGln: 3.209 ± 0.064	3.687ArgArg: 3.687 ± 0.073	3.308ArgSer: 3.308 ± 0.069	2.624ArgThr: 2.624 ± 0.058	3.238ArgVal: 3.238 ± 0.068	0.693ArgTrp: 0.693 ± 0.033	1.687ArgTyr: 1.687 ± 0.048	0.0ArgXaa: 0.0 ± 0.0
Ser	5.074SerAla: 5.074 ± 0.099	1.033SerCys: 1.033 ± 0.038	2.753SerAsp: 2.753 ± 0.067	3.476SerGlu: 3.476 ± 0.057	2.916SerPhe: 2.916 ± 0.065	5.717SerGly: 5.717 ± 0.097	1.058SerHis: 1.058 ± 0.034	3.652SerIle: 3.652 ± 0.075	2.969SerLys: 2.969 ± 0.07	6.414SerLeu: 6.414 ± 0.114	1.446SerMet: 1.446 ± 0.042	1.934SerAsn: 1.934 ± 0.06	2.531SerPro: 2.531 ± 0.058	2.129SerGln: 2.129 ± 0.044	3.354SerArg: 3.354 ± 0.065	4.357SerSer: 4.357 ± 0.103	2.804SerThr: 2.804 ± 0.077	4.047SerVal: 4.047 ± 0.072	0.925SerTrp: 0.925 ± 0.034	1.826SerTyr: 1.826 ± 0.054	0.0SerXaa: 0.0 ± 0.0
Thr	5.638ThrAla: 5.638 ± 0.114	0.663ThrCys: 0.663 ± 0.032	2.608ThrAsp: 2.608 ± 0.064	3.269ThrGlu: 3.269 ± 0.066	1.801ThrPhe: 1.801 ± 0.049	4.611ThrGly: 4.611 ± 0.084	0.885ThrHis: 0.885 ± 0.037	2.798ThrIle: 2.798 ± 0.061	2.136ThrLys: 2.136 ± 0.054	5.218ThrLeu: 5.218 ± 0.092	1.028ThrMet: 1.028 ± 0.034	1.497ThrAsn: 1.497 ± 0.051	2.374ThrPro: 2.374 ± 0.06	1.553ThrGln: 1.553 ± 0.037	2.079ThrArg: 2.079 ± 0.054	2.739ThrSer: 2.739 ± 0.076	2.395ThrThr: 2.395 ± 0.071	4.46ThrVal: 4.46 ± 0.084	0.629ThrTrp: 0.629 ± 0.034	1.255ThrTyr: 1.255 ± 0.046	0.0ThrXaa: 0.0 ± 0.0
Val	5.823ValAla: 5.823 ± 0.094	0.986ValCys: 0.986 ± 0.037	3.292ValAsp: 3.292 ± 0.065	4.156ValGlu: 4.156 ± 0.077	2.819ValPhe: 2.819 ± 0.064	4.218ValGly: 4.218 ± 0.094	1.279ValHis: 1.279 ± 0.041	4.258ValIle: 4.258 ± 0.079	3.208ValLys: 3.208 ± 0.057	7.391ValLeu: 7.391 ± 0.095	1.699ValMet: 1.699 ± 0.046	2.465ValAsn: 2.465 ± 0.059	2.856ValPro: 2.856 ± 0.063	2.727ValGln: 2.727 ± 0.063	4.038ValArg: 4.038 ± 0.073	4.324ValSer: 4.324 ± 0.077	3.498ValThr: 3.498 ± 0.084	4.498ValVal: 4.498 ± 0.088	0.65ValTrp: 0.65 ± 0.028	1.728ValTyr: 1.728 ± 0.048	0.0ValXaa: 0.0 ± 0.0
Trp	0.783TrpAla: 0.783 ± 0.035	0.173TrpCys: 0.173 ± 0.014	0.531TrpAsp: 0.531 ± 0.028	0.641TrpGlu: 0.641 ± 0.027	0.521TrpPhe: 0.521 ± 0.027	0.628TrpGly: 0.628 ± 0.028	0.303TrpHis: 0.303 ± 0.02	0.632TrpIle: 0.632 ± 0.033	0.587TrpLys: 0.587 ± 0.031	1.466TrpLeu: 1.466 ± 0.055	0.293TrpMet: 0.293 ± 0.017	0.526TrpAsn: 0.526 ± 0.029	0.49TrpPro: 0.49 ± 0.026	0.914TrpGln: 0.914 ± 0.037	0.737TrpArg: 0.737 ± 0.029	0.672TrpSer: 0.672 ± 0.033	0.5TrpThr: 0.5 ± 0.028	0.564TrpVal: 0.564 ± 0.029	0.159TrpTrp: 0.159 ± 0.016	0.315TrpTyr: 0.315 ± 0.018	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.194TyrAla: 2.194 ± 0.055	0.412TyrCys: 0.412 ± 0.022	1.5TyrAsp: 1.5 ± 0.05	1.667TyrGlu: 1.667 ± 0.05	1.332TyrPhe: 1.332 ± 0.044	2.047TyrGly: 2.047 ± 0.053	0.639TyrHis: 0.639 ± 0.027	1.537TyrIle: 1.537 ± 0.046	1.279TyrLys: 1.279 ± 0.041	3.009TyrLeu: 3.009 ± 0.066	0.544TyrMet: 0.544 ± 0.027	0.96TyrAsn: 0.96 ± 0.041	1.256TyrPro: 1.256 ± 0.038	1.184TyrGln: 1.184 ± 0.044	1.711TyrArg: 1.711 ± 0.048	1.927TyrSer: 1.927 ± 0.052	1.41TyrThr: 1.41 ± 0.046	1.538TyrVal: 1.538 ± 0.046	0.382TyrTrp: 0.382 ± 0.021	0.91TyrTyr: 0.91 ± 0.044	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 2614 proteins (805550 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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