Amino acid dipepetide frequency for Rice dwarf virus (isolate Fujian) (RDV)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.465AlaAla: 4.465 ± 0.829
0.765AlaCys: 0.765 ± 0.329
4.337AlaAsp: 4.337 ± 0.885
2.551AlaGlu: 2.551 ± 0.488
2.551AlaPhe: 2.551 ± 0.505
2.934AlaGly: 2.934 ± 0.749
1.531AlaHis: 1.531 ± 0.397
4.72AlaIle: 4.72 ± 0.732
3.189AlaLys: 3.189 ± 0.612
7.782AlaLeu: 7.782 ± 1.328
1.914AlaMet: 1.914 ± 0.513
4.465AlaAsn: 4.465 ± 0.56
2.296AlaPro: 2.296 ± 0.429
2.424AlaGln: 2.424 ± 0.553
2.806AlaArg: 2.806 ± 0.455
5.485AlaSer: 5.485 ± 0.822
4.21AlaThr: 4.21 ± 0.479
3.189AlaVal: 3.189 ± 0.617
0.893AlaTrp: 0.893 ± 0.222
4.592AlaTyr: 4.592 ± 0.711
0.0AlaXaa: 0.0 ± 0.0
Cys
0.893CysAla: 0.893 ± 0.401
0.0CysCys: 0.0 ± 0.0
0.638CysAsp: 0.638 ± 0.175
0.51CysGlu: 0.51 ± 0.241
0.638CysPhe: 0.638 ± 0.261
1.276CysGly: 1.276 ± 0.38
0.383CysHis: 0.383 ± 0.235
0.383CysIle: 0.383 ± 0.214
0.383CysLys: 0.383 ± 0.215
2.041CysLeu: 2.041 ± 0.596
0.383CysMet: 0.383 ± 0.224
0.383CysAsn: 0.383 ± 0.194
0.765CysPro: 0.765 ± 0.295
0.255CysGln: 0.255 ± 0.193
0.638CysArg: 0.638 ± 0.336
0.893CysSer: 0.893 ± 0.351
0.128CysThr: 0.128 ± 0.107
0.383CysVal: 0.383 ± 0.219
0.128CysTrp: 0.128 ± 0.107
0.51CysTyr: 0.51 ± 0.21
0.0CysXaa: 0.0 ± 0.0
Asp
4.465AspAla: 4.465 ± 0.673
1.148AspCys: 1.148 ± 0.344
4.082AspAsp: 4.082 ± 0.558
3.572AspGlu: 3.572 ± 0.839
3.189AspPhe: 3.189 ± 0.52
3.827AspGly: 3.827 ± 0.677
0.51AspHis: 0.51 ± 0.199
3.572AspIle: 3.572 ± 0.471
2.679AspLys: 2.679 ± 0.595
6.889AspLeu: 6.889 ± 1.376
1.403AspMet: 1.403 ± 0.481
2.424AspAsn: 2.424 ± 0.511
2.551AspPro: 2.551 ± 0.385
1.531AspGln: 1.531 ± 0.468
2.551AspArg: 2.551 ± 0.364
5.23AspSer: 5.23 ± 0.69
3.827AspThr: 3.827 ± 0.552
5.868AspVal: 5.868 ± 1.296
1.021AspTrp: 1.021 ± 0.342
2.806AspTyr: 2.806 ± 0.691
0.0AspXaa: 0.0 ± 0.0
Glu
4.082GluAla: 4.082 ± 0.536
0.51GluCys: 0.51 ± 0.227
2.424GluAsp: 2.424 ± 0.817
2.424GluGlu: 2.424 ± 0.551
1.914GluPhe: 1.914 ± 0.319
2.169GluGly: 2.169 ± 0.457
1.021GluHis: 1.021 ± 0.282
3.444GluIle: 3.444 ± 0.628
2.551GluLys: 2.551 ± 0.71
4.337GluLeu: 4.337 ± 0.467
0.893GluMet: 0.893 ± 0.468
1.786GluAsn: 1.786 ± 0.358
2.169GluPro: 2.169 ± 0.494
1.276GluGln: 1.276 ± 0.254
2.806GluArg: 2.806 ± 0.483
3.827GluSer: 3.827 ± 0.833
2.296GluThr: 2.296 ± 0.317
4.082GluVal: 4.082 ± 0.505
0.255GluTrp: 0.255 ± 0.164
1.531GluTyr: 1.531 ± 0.58
0.0GluXaa: 0.0 ± 0.0
Phe
1.786PheAla: 1.786 ± 0.304
0.893PheCys: 0.893 ± 0.305
2.296PheAsp: 2.296 ± 0.691
2.169PheGlu: 2.169 ± 0.375
1.914PhePhe: 1.914 ± 0.434
2.679PheGly: 2.679 ± 0.65
0.638PheHis: 0.638 ± 0.276
2.806PheIle: 2.806 ± 0.499
2.551PheLys: 2.551 ± 0.521
2.934PheLeu: 2.934 ± 0.651
1.403PheMet: 1.403 ± 0.345
1.786PheAsn: 1.786 ± 0.478
1.276PhePro: 1.276 ± 0.536
1.658PheGln: 1.658 ± 0.506
2.551PheArg: 2.551 ± 0.485
4.082PheSer: 4.082 ± 0.714
3.955PheThr: 3.955 ± 0.695
3.827PheVal: 3.827 ± 0.489
0.51PheTrp: 0.51 ± 0.255
0.893PheTyr: 0.893 ± 0.228
0.0PheXaa: 0.0 ± 0.0
Gly
3.062GlyAla: 3.062 ± 0.698
0.255GlyCys: 0.255 ± 0.168
3.827GlyAsp: 3.827 ± 0.837
2.424GlyGlu: 2.424 ± 0.705
2.551GlyPhe: 2.551 ± 0.439
3.572GlyGly: 3.572 ± 0.433
1.531GlyHis: 1.531 ± 0.429
3.827GlyIle: 3.827 ± 0.566
2.806GlyLys: 2.806 ± 0.577
4.848GlyLeu: 4.848 ± 0.754
1.276GlyMet: 1.276 ± 0.361
2.934GlyAsn: 2.934 ± 0.725
2.041GlyPro: 2.041 ± 0.62
1.403GlyGln: 1.403 ± 0.299
2.806GlyArg: 2.806 ± 0.368
5.868GlySer: 5.868 ± 0.96
2.424GlyThr: 2.424 ± 0.545
4.082GlyVal: 4.082 ± 0.639
0.383GlyTrp: 0.383 ± 0.215
1.786GlyTyr: 1.786 ± 0.492
0.0GlyXaa: 0.0 ± 0.0
His
1.403HisAla: 1.403 ± 0.463
0.255HisCys: 0.255 ± 0.153
1.021HisAsp: 1.021 ± 0.259
2.041HisGlu: 2.041 ± 0.467
0.893HisPhe: 0.893 ± 0.326
0.765HisGly: 0.765 ± 0.239
0.765HisHis: 0.765 ± 0.367
0.765HisIle: 0.765 ± 0.399
1.658HisLys: 1.658 ± 0.343
2.551HisLeu: 2.551 ± 0.374
0.51HisMet: 0.51 ± 0.274
0.893HisAsn: 0.893 ± 0.287
1.021HisPro: 1.021 ± 0.317
0.51HisGln: 0.51 ± 0.227
1.021HisArg: 1.021 ± 0.386
1.148HisSer: 1.148 ± 0.37
0.638HisThr: 0.638 ± 0.226
1.658HisVal: 1.658 ± 0.36
0.383HisTrp: 0.383 ± 0.173
1.021HisTyr: 1.021 ± 0.348
0.0HisXaa: 0.0 ± 0.0
Ile
3.699IleAla: 3.699 ± 0.376
0.765IleCys: 0.765 ± 0.427
3.955IleAsp: 3.955 ± 0.938
2.041IleGlu: 2.041 ± 0.543
1.914IlePhe: 1.914 ± 0.378
3.317IleGly: 3.317 ± 0.438
1.148IleHis: 1.148 ± 0.415
3.827IleIle: 3.827 ± 0.848
3.317IleLys: 3.317 ± 0.266
6.889IleLeu: 6.889 ± 0.67
1.276IleMet: 1.276 ± 0.323
3.955IleAsn: 3.955 ± 0.443
2.551IlePro: 2.551 ± 0.788
1.658IleGln: 1.658 ± 0.381
2.934IleArg: 2.934 ± 0.399
6.378IleSer: 6.378 ± 1.073
5.868IleThr: 5.868 ± 0.625
4.082IleVal: 4.082 ± 0.757
0.255IleTrp: 0.255 ± 0.151
2.551IleTyr: 2.551 ± 0.8
0.0IleXaa: 0.0 ± 0.0
Lys
3.444LysAla: 3.444 ± 0.641
0.638LysCys: 0.638 ± 0.321
2.296LysAsp: 2.296 ± 0.498
1.786LysGlu: 1.786 ± 0.564
2.296LysPhe: 2.296 ± 0.612
2.169LysGly: 2.169 ± 0.572
1.276LysHis: 1.276 ± 0.328
3.062LysIle: 3.062 ± 0.413
2.679LysLys: 2.679 ± 0.521
6.251LysLeu: 6.251 ± 0.745
1.531LysMet: 1.531 ± 0.469
2.934LysAsn: 2.934 ± 0.615
2.041LysPro: 2.041 ± 0.532
0.765LysGln: 0.765 ± 0.277
3.572LysArg: 3.572 ± 0.908
6.123LysSer: 6.123 ± 1.18
2.551LysThr: 2.551 ± 0.347
3.955LysVal: 3.955 ± 0.383
0.255LysTrp: 0.255 ± 0.273
2.934LysTyr: 2.934 ± 0.763
0.0LysXaa: 0.0 ± 0.0
Leu
7.271LeuAla: 7.271 ± 0.886
1.276LeuCys: 1.276 ± 0.33
6.251LeuAsp: 6.251 ± 0.9
3.062LeuGlu: 3.062 ± 0.893
3.572LeuPhe: 3.572 ± 0.644
5.358LeuGly: 5.358 ± 1.031
2.041LeuHis: 2.041 ± 0.705
6.123LeuIle: 6.123 ± 0.739
6.123LeuLys: 6.123 ± 0.892
7.909LeuLeu: 7.909 ± 0.562
2.424LeuMet: 2.424 ± 0.528
5.358LeuAsn: 5.358 ± 0.786
4.465LeuPro: 4.465 ± 0.395
2.806LeuGln: 2.806 ± 0.575
5.741LeuArg: 5.741 ± 0.654
11.481LeuSer: 11.481 ± 1.337
6.378LeuThr: 6.378 ± 0.782
5.23LeuVal: 5.23 ± 1.16
0.638LeuTrp: 0.638 ± 0.25
2.424LeuTyr: 2.424 ± 0.461
0.0LeuXaa: 0.0 ± 0.0
Met
1.531MetAla: 1.531 ± 0.296
0.255MetCys: 0.255 ± 0.147
1.786MetAsp: 1.786 ± 0.398
1.148MetGlu: 1.148 ± 0.385
1.786MetPhe: 1.786 ± 0.475
0.765MetGly: 0.765 ± 0.364
0.765MetHis: 0.765 ± 0.284
1.786MetIle: 1.786 ± 0.493
1.914MetLys: 1.914 ± 0.494
3.955MetLeu: 3.955 ± 0.541
0.893MetMet: 0.893 ± 0.234
1.658MetAsn: 1.658 ± 0.414
1.148MetPro: 1.148 ± 0.287
1.403MetGln: 1.403 ± 0.281
1.148MetArg: 1.148 ± 0.354
3.444MetSer: 3.444 ± 0.929
1.276MetThr: 1.276 ± 0.326
1.531MetVal: 1.531 ± 0.353
0.383MetTrp: 0.383 ± 0.163
0.51MetTyr: 0.51 ± 0.165
0.0MetXaa: 0.0 ± 0.0
Asn
4.848AsnAla: 4.848 ± 0.614
0.893AsnCys: 0.893 ± 0.34
2.679AsnAsp: 2.679 ± 0.419
2.551AsnGlu: 2.551 ± 0.671
2.551AsnPhe: 2.551 ± 0.395
2.934AsnGly: 2.934 ± 0.583
0.765AsnHis: 0.765 ± 0.266
3.827AsnIle: 3.827 ± 0.563
2.551AsnLys: 2.551 ± 0.642
5.358AsnLeu: 5.358 ± 0.542
2.551AsnMet: 2.551 ± 0.672
2.296AsnAsn: 2.296 ± 0.581
2.679AsnPro: 2.679 ± 0.705
1.531AsnGln: 1.531 ± 0.443
1.914AsnArg: 1.914 ± 0.322
4.337AsnSer: 4.337 ± 0.453
3.189AsnThr: 3.189 ± 0.728
4.337AsnVal: 4.337 ± 0.612
0.255AsnTrp: 0.255 ± 0.131
1.531AsnTyr: 1.531 ± 0.299
0.0AsnXaa: 0.0 ± 0.0
Pro
3.699ProAla: 3.699 ± 0.712
0.128ProCys: 0.128 ± 0.148
3.189ProAsp: 3.189 ± 0.41
1.403ProGlu: 1.403 ± 0.429
1.786ProPhe: 1.786 ± 0.427
2.169ProGly: 2.169 ± 0.572
0.893ProHis: 0.893 ± 0.475
2.551ProIle: 2.551 ± 0.77
1.914ProLys: 1.914 ± 0.591
3.062ProLeu: 3.062 ± 0.352
0.765ProMet: 0.765 ± 0.288
2.679ProAsn: 2.679 ± 0.803
2.424ProPro: 2.424 ± 0.569
2.041ProGln: 2.041 ± 0.301
1.914ProArg: 1.914 ± 0.571
4.337ProSer: 4.337 ± 0.764
2.424ProThr: 2.424 ± 0.356
3.317ProVal: 3.317 ± 0.654
0.383ProTrp: 0.383 ± 0.215
1.531ProTyr: 1.531 ± 0.364
0.0ProXaa: 0.0 ± 0.0
Gln
2.934GlnAla: 2.934 ± 0.468
0.128GlnCys: 0.128 ± 0.157
2.041GlnAsp: 2.041 ± 0.405
1.276GlnGlu: 1.276 ± 0.483
0.638GlnPhe: 0.638 ± 0.258
1.276GlnGly: 1.276 ± 0.26
0.255GlnHis: 0.255 ± 0.131
1.148GlnIle: 1.148 ± 0.488
1.914GlnLys: 1.914 ± 0.413
3.955GlnLeu: 3.955 ± 0.942
1.021GlnMet: 1.021 ± 0.297
1.786GlnAsn: 1.786 ± 0.315
1.276GlnPro: 1.276 ± 0.363
0.765GlnGln: 0.765 ± 0.473
1.276GlnArg: 1.276 ± 0.551
3.189GlnSer: 3.189 ± 0.442
2.296GlnThr: 2.296 ± 0.561
1.786GlnVal: 1.786 ± 0.313
0.255GlnTrp: 0.255 ± 0.181
1.276GlnTyr: 1.276 ± 0.257
0.0GlnXaa: 0.0 ± 0.0
Arg
3.317ArgAla: 3.317 ± 0.636
0.638ArgCys: 0.638 ± 0.379
2.806ArgAsp: 2.806 ± 0.613
2.169ArgGlu: 2.169 ± 0.36
1.658ArgPhe: 1.658 ± 0.311
2.424ArgGly: 2.424 ± 0.378
1.403ArgHis: 1.403 ± 0.234
2.806ArgIle: 2.806 ± 0.517
3.572ArgLys: 3.572 ± 0.971
3.955ArgLeu: 3.955 ± 0.736
1.914ArgMet: 1.914 ± 0.436
3.572ArgAsn: 3.572 ± 0.732
1.786ArgPro: 1.786 ± 0.242
1.276ArgGln: 1.276 ± 0.449
2.424ArgArg: 2.424 ± 0.55
4.72ArgSer: 4.72 ± 0.686
3.062ArgThr: 3.062 ± 0.583
3.444ArgVal: 3.444 ± 0.503
0.383ArgTrp: 0.383 ± 0.275
1.658ArgTyr: 1.658 ± 0.225
0.0ArgXaa: 0.0 ± 0.0
Ser
4.975SerAla: 4.975 ± 0.672
0.383SerCys: 0.383 ± 0.227
7.016SerAsp: 7.016 ± 1.138
6.123SerGlu: 6.123 ± 0.988
4.082SerPhe: 4.082 ± 0.498
6.123SerGly: 6.123 ± 1.225
2.169SerHis: 2.169 ± 0.366
5.358SerIle: 5.358 ± 0.467
5.741SerLys: 5.741 ± 1.021
7.144SerLeu: 7.144 ± 0.767
3.444SerMet: 3.444 ± 0.516
5.996SerAsn: 5.996 ± 0.476
2.934SerPro: 2.934 ± 0.539
3.189SerGln: 3.189 ± 0.533
4.465SerArg: 4.465 ± 0.65
8.292SerSer: 8.292 ± 1.081
5.868SerThr: 5.868 ± 1.15
8.93SerVal: 8.93 ± 1.207
0.638SerTrp: 0.638 ± 0.215
3.444SerTyr: 3.444 ± 0.517
0.0SerXaa: 0.0 ± 0.0
Thr
4.21ThrAla: 4.21 ± 0.676
0.51ThrCys: 0.51 ± 0.219
4.21ThrAsp: 4.21 ± 0.526
3.062ThrGlu: 3.062 ± 0.619
2.679ThrPhe: 2.679 ± 0.605
4.337ThrGly: 4.337 ± 0.523
1.021ThrHis: 1.021 ± 0.395
4.592ThrIle: 4.592 ± 0.797
1.914ThrLys: 1.914 ± 0.703
5.103ThrLeu: 5.103 ± 0.582
1.658ThrMet: 1.658 ± 0.359
2.041ThrAsn: 2.041 ± 0.514
3.062ThrPro: 3.062 ± 0.656
2.296ThrGln: 2.296 ± 0.506
2.551ThrArg: 2.551 ± 0.669
6.633ThrSer: 6.633 ± 0.728
4.21ThrThr: 4.21 ± 0.768
4.465ThrVal: 4.465 ± 0.771
0.51ThrTrp: 0.51 ± 0.247
2.679ThrTyr: 2.679 ± 0.478
0.0ThrXaa: 0.0 ± 0.0
Val
3.444ValAla: 3.444 ± 0.755
1.148ValCys: 1.148 ± 0.371
5.103ValAsp: 5.103 ± 0.866
2.424ValGlu: 2.424 ± 0.678
3.444ValPhe: 3.444 ± 0.739
3.062ValGly: 3.062 ± 0.515
1.786ValHis: 1.786 ± 0.532
5.103ValIle: 5.103 ± 0.575
3.444ValLys: 3.444 ± 0.582
7.016ValLeu: 7.016 ± 0.973
1.786ValMet: 1.786 ± 0.302
3.955ValAsn: 3.955 ± 0.696
4.465ValPro: 4.465 ± 0.823
1.914ValGln: 1.914 ± 0.501
3.699ValArg: 3.699 ± 0.652
6.761ValSer: 6.761 ± 0.628
4.72ValThr: 4.72 ± 0.731
4.592ValVal: 4.592 ± 0.774
0.638ValTrp: 0.638 ± 0.157
4.082ValTyr: 4.082 ± 0.985
0.0ValXaa: 0.0 ± 0.0
Trp
0.638TrpAla: 0.638 ± 0.324
0.128TrpCys: 0.128 ± 0.097
0.893TrpAsp: 0.893 ± 0.255
0.255TrpGlu: 0.255 ± 0.179
0.765TrpPhe: 0.765 ± 0.397
0.128TrpGly: 0.128 ± 0.107
0.255TrpHis: 0.255 ± 0.153
0.638TrpIle: 0.638 ± 0.246
0.255TrpLys: 0.255 ± 0.178
1.021TrpLeu: 1.021 ± 0.387
0.128TrpMet: 0.128 ± 0.106
0.383TrpAsn: 0.383 ± 0.175
0.128TrpPro: 0.128 ± 0.134
0.255TrpGln: 0.255 ± 0.133
0.51TrpArg: 0.51 ± 0.236
0.51TrpSer: 0.51 ± 0.235
0.51TrpThr: 0.51 ± 0.404
0.51TrpVal: 0.51 ± 0.224
0.0TrpTrp: 0.0 ± 0.0
0.51TrpTyr: 0.51 ± 0.412
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.062TyrAla: 3.062 ± 0.544
0.893TyrCys: 0.893 ± 0.341
2.296TyrAsp: 2.296 ± 0.67
2.806TyrGlu: 2.806 ± 0.562
1.786TyrPhe: 1.786 ± 0.521
2.424TyrGly: 2.424 ± 0.422
0.765TyrHis: 0.765 ± 0.337
2.041TyrIle: 2.041 ± 0.482
1.403TyrLys: 1.403 ± 0.351
2.934TyrLeu: 2.934 ± 0.565
1.786TyrMet: 1.786 ± 0.445
2.296TyrAsn: 2.296 ± 0.589
1.531TyrPro: 1.531 ± 0.306
1.531TyrGln: 1.531 ± 0.32
1.658TyrArg: 1.658 ± 0.506
3.572TyrSer: 3.572 ± 0.614
1.914TyrThr: 1.914 ± 0.677
3.317TyrVal: 3.317 ± 0.805
0.255TyrTrp: 0.255 ± 0.153
2.169TyrTyr: 2.169 ± 0.851
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 13 proteins (7840 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski