Amino acid dipepetide frequency for Anguillid herpesvirus 1 (isolate Anguilla anguilla/Netherlands/500138/1998) (AngHV-1) (European eel herpesvirus)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
9.203AlaAla: 9.203 ± 0.534
1.644AlaCys: 1.644 ± 0.221
4.974AlaAsp: 4.974 ± 0.266
5.128AlaGlu: 5.128 ± 0.259
2.684AlaPhe: 2.684 ± 0.215
4.44AlaGly: 4.44 ± 0.312
1.728AlaHis: 1.728 ± 0.162
3.428AlaIle: 3.428 ± 0.257
3.639AlaLys: 3.639 ± 0.277
6.463AlaLeu: 6.463 ± 0.344
2.178AlaMet: 2.178 ± 0.209
2.866AlaAsn: 2.866 ± 0.224
5.508AlaPro: 5.508 ± 0.523
3.344AlaGln: 3.344 ± 0.219
4.046AlaArg: 4.046 ± 0.302
4.974AlaSer: 4.974 ± 0.32
4.946AlaThr: 4.946 ± 0.311
6.336AlaVal: 6.336 ± 0.325
1.124AlaTrp: 1.124 ± 0.116
2.22AlaTyr: 2.22 ± 0.162
0.0AlaXaa: 0.0 ± 0.0
Cys
1.728CysAla: 1.728 ± 0.201
0.393CysCys: 0.393 ± 0.112
1.377CysAsp: 1.377 ± 0.174
0.969CysGlu: 0.969 ± 0.138
0.717CysPhe: 0.717 ± 0.099
1.18CysGly: 1.18 ± 0.158
0.562CysHis: 0.562 ± 0.095
0.52CysIle: 0.52 ± 0.087
0.983CysLys: 0.983 ± 0.135
1.742CysLeu: 1.742 ± 0.17
0.548CysMet: 0.548 ± 0.091
0.815CysAsn: 0.815 ± 0.129
1.25CysPro: 1.25 ± 0.156
0.562CysGln: 0.562 ± 0.094
1.026CysArg: 1.026 ± 0.118
1.405CysSer: 1.405 ± 0.149
1.068CysThr: 1.068 ± 0.164
1.826CysVal: 1.826 ± 0.184
0.309CysTrp: 0.309 ± 0.082
0.646CysTyr: 0.646 ± 0.091
0.0CysXaa: 0.0 ± 0.0
Asp
4.018AspAla: 4.018 ± 0.259
1.096AspCys: 1.096 ± 0.172
4.412AspAsp: 4.412 ± 0.386
4.37AspGlu: 4.37 ± 0.404
1.869AspPhe: 1.869 ± 0.15
3.836AspGly: 3.836 ± 0.225
1.461AspHis: 1.461 ± 0.128
2.107AspIle: 2.107 ± 0.194
2.15AspLys: 2.15 ± 0.206
5.128AspLeu: 5.128 ± 0.288
1.461AspMet: 1.461 ± 0.137
1.616AspAsn: 1.616 ± 0.134
3.611AspPro: 3.611 ± 0.219
2.417AspGln: 2.417 ± 0.18
4.44AspArg: 4.44 ± 0.274
3.597AspSer: 3.597 ± 0.288
3.091AspThr: 3.091 ± 0.222
4.187AspVal: 4.187 ± 0.264
1.236AspTrp: 1.236 ± 0.122
1.7AspTyr: 1.7 ± 0.155
0.0AspXaa: 0.0 ± 0.0
Glu
4.032GluAla: 4.032 ± 0.272
1.082GluCys: 1.082 ± 0.153
3.836GluAsp: 3.836 ± 0.338
6.07GluGlu: 6.07 ± 0.738
1.897GluPhe: 1.897 ± 0.145
3.386GluGly: 3.386 ± 0.36
1.264GluHis: 1.264 ± 0.14
2.079GluIle: 2.079 ± 0.179
2.936GluLys: 2.936 ± 0.244
6.112GluLeu: 6.112 ± 0.333
1.925GluMet: 1.925 ± 0.183
1.953GluAsn: 1.953 ± 0.181
4.44GluPro: 4.44 ± 0.391
2.543GluGln: 2.543 ± 0.222
3.569GluArg: 3.569 ± 0.345
3.906GluSer: 3.906 ± 0.292
4.37GluThr: 4.37 ± 0.223
3.372GluVal: 3.372 ± 0.226
1.391GluTrp: 1.391 ± 0.199
1.433GluTyr: 1.433 ± 0.145
0.0GluXaa: 0.0 ± 0.0
Phe
2.318PheAla: 2.318 ± 0.176
0.717PheCys: 0.717 ± 0.094
2.248PheAsp: 2.248 ± 0.179
2.487PheGlu: 2.487 ± 0.192
1.419PhePhe: 1.419 ± 0.156
2.403PheGly: 2.403 ± 0.188
0.885PheHis: 0.885 ± 0.115
1.63PheIle: 1.63 ± 0.151
2.15PheLys: 2.15 ± 0.2
2.712PheLeu: 2.712 ± 0.173
0.969PheMet: 0.969 ± 0.102
1.981PheAsn: 1.981 ± 0.202
1.672PhePro: 1.672 ± 0.157
1.447PheGln: 1.447 ± 0.142
1.728PheArg: 1.728 ± 0.133
2.936PheSer: 2.936 ± 0.242
2.431PheThr: 2.431 ± 0.176
2.627PheVal: 2.627 ± 0.179
0.745PheTrp: 0.745 ± 0.105
1.25PheTyr: 1.25 ± 0.148
0.0PheXaa: 0.0 ± 0.0
Gly
4.271GlyAla: 4.271 ± 0.265
0.983GlyCys: 0.983 ± 0.13
3.133GlyAsp: 3.133 ± 0.205
3.793GlyGlu: 3.793 ± 0.354
2.107GlyPhe: 2.107 ± 0.167
4.285GlyGly: 4.285 ± 0.632
1.377GlyHis: 1.377 ± 0.153
2.431GlyIle: 2.431 ± 0.193
2.796GlyLys: 2.796 ± 0.205
5.339GlyLeu: 5.339 ± 0.303
1.18GlyMet: 1.18 ± 0.158
2.051GlyAsn: 2.051 ± 0.257
3.934GlyPro: 3.934 ± 0.279
2.122GlyGln: 2.122 ± 0.157
3.175GlyArg: 3.175 ± 0.239
4.229GlySer: 4.229 ± 0.283
3.597GlyThr: 3.597 ± 0.203
4.285GlyVal: 4.285 ± 0.249
0.998GlyTrp: 0.998 ± 0.13
1.644GlyTyr: 1.644 ± 0.214
0.0GlyXaa: 0.0 ± 0.0
His
1.742HisAla: 1.742 ± 0.166
0.365HisCys: 0.365 ± 0.071
0.843HisAsp: 0.843 ± 0.114
1.166HisGlu: 1.166 ± 0.119
0.913HisPhe: 0.913 ± 0.113
1.279HisGly: 1.279 ± 0.108
0.843HisHis: 0.843 ± 0.112
1.166HisIle: 1.166 ± 0.151
1.293HisLys: 1.293 ± 0.15
1.841HisLeu: 1.841 ± 0.144
0.688HisMet: 0.688 ± 0.115
1.054HisAsn: 1.054 ± 0.119
1.194HisPro: 1.194 ± 0.149
0.604HisGln: 0.604 ± 0.083
1.7HisArg: 1.7 ± 0.154
1.461HisSer: 1.461 ± 0.157
1.967HisThr: 1.967 ± 0.155
1.784HisVal: 1.784 ± 0.161
0.478HisTrp: 0.478 ± 0.071
0.787HisTyr: 0.787 ± 0.103
0.0HisXaa: 0.0 ± 0.0
Ile
3.007IleAla: 3.007 ± 0.222
0.941IleCys: 0.941 ± 0.137
2.529IleAsp: 2.529 ± 0.192
2.529IleGlu: 2.529 ± 0.132
1.672IlePhe: 1.672 ± 0.153
2.585IleGly: 2.585 ± 0.209
0.983IleHis: 0.983 ± 0.126
1.293IleIle: 1.293 ± 0.152
2.501IleLys: 2.501 ± 0.189
3.414IleLeu: 3.414 ± 0.215
0.983IleMet: 0.983 ± 0.114
1.686IleAsn: 1.686 ± 0.159
2.698IlePro: 2.698 ± 0.19
1.56IleGln: 1.56 ± 0.217
2.318IleArg: 2.318 ± 0.166
2.866IleSer: 2.866 ± 0.275
2.501IleThr: 2.501 ± 0.224
3.316IleVal: 3.316 ± 0.215
0.688IleTrp: 0.688 ± 0.078
1.18IleTyr: 1.18 ± 0.123
0.0IleXaa: 0.0 ± 0.0
Lys
3.217LysAla: 3.217 ± 0.268
1.096LysCys: 1.096 ± 0.143
2.529LysAsp: 2.529 ± 0.168
2.754LysGlu: 2.754 ± 0.302
1.7LysPhe: 1.7 ± 0.17
2.417LysGly: 2.417 ± 0.174
1.012LysHis: 1.012 ± 0.137
2.051LysIle: 2.051 ± 0.206
3.33LysLys: 3.33 ± 0.282
5.1LysLeu: 5.1 ± 0.272
1.138LysMet: 1.138 ± 0.12
1.602LysAsn: 1.602 ± 0.148
3.344LysPro: 3.344 ± 0.32
2.051LysGln: 2.051 ± 0.169
3.765LysArg: 3.765 ± 0.271
2.965LysSer: 2.965 ± 0.204
3.906LysThr: 3.906 ± 0.23
3.035LysVal: 3.035 ± 0.227
1.152LysTrp: 1.152 ± 0.156
1.377LysTyr: 1.377 ± 0.147
0.0LysXaa: 0.0 ± 0.0
Leu
6.435LeuAla: 6.435 ± 0.384
1.77LeuCys: 1.77 ± 0.187
5.156LeuAsp: 5.156 ± 0.244
5.423LeuGlu: 5.423 ± 0.305
3.681LeuPhe: 3.681 ± 0.235
4.833LeuGly: 4.833 ± 0.26
1.939LeuHis: 1.939 ± 0.208
4.187LeuIle: 4.187 ± 0.293
5.142LeuLys: 5.142 ± 0.373
7.489LeuLeu: 7.489 ± 0.305
2.29LeuMet: 2.29 ± 0.18
4.243LeuAsn: 4.243 ± 0.282
5.508LeuPro: 5.508 ± 0.284
2.979LeuGln: 2.979 ± 0.262
4.665LeuArg: 4.665 ± 0.245
6.126LeuSer: 6.126 ± 0.299
7.081LeuThr: 7.081 ± 0.361
5.774LeuVal: 5.774 ± 0.292
1.321LeuTrp: 1.321 ± 0.169
2.543LeuTyr: 2.543 ± 0.176
0.0LeuXaa: 0.0 ± 0.0
Met
2.74MetAla: 2.74 ± 0.239
0.688MetCys: 0.688 ± 0.094
1.349MetAsp: 1.349 ± 0.123
1.602MetGlu: 1.602 ± 0.178
1.138MetPhe: 1.138 ± 0.124
1.363MetGly: 1.363 ± 0.137
0.464MetHis: 0.464 ± 0.078
1.068MetIle: 1.068 ± 0.138
0.955MetLys: 0.955 ± 0.109
2.388MetLeu: 2.388 ± 0.182
0.815MetMet: 0.815 ± 0.111
1.012MetAsn: 1.012 ± 0.119
1.335MetPro: 1.335 ± 0.141
0.562MetGln: 0.562 ± 0.071
1.082MetArg: 1.082 ± 0.104
1.728MetSer: 1.728 ± 0.154
1.672MetThr: 1.672 ± 0.163
1.925MetVal: 1.925 ± 0.179
0.464MetTrp: 0.464 ± 0.083
0.717MetTyr: 0.717 ± 0.102
0.0MetXaa: 0.0 ± 0.0
Asn
2.838AsnAla: 2.838 ± 0.232
0.688AsnCys: 0.688 ± 0.093
1.588AsnAsp: 1.588 ± 0.15
1.728AsnGlu: 1.728 ± 0.17
1.222AsnPhe: 1.222 ± 0.125
2.908AsnGly: 2.908 ± 0.256
0.857AsnHis: 0.857 ± 0.106
1.545AsnIle: 1.545 ± 0.167
2.107AsnLys: 2.107 ± 0.206
3.569AsnLeu: 3.569 ± 0.292
1.04AsnMet: 1.04 ± 0.141
1.63AsnAsn: 1.63 ± 0.198
2.501AsnPro: 2.501 ± 0.185
1.293AsnGln: 1.293 ± 0.159
2.768AsnArg: 2.768 ± 0.193
2.388AsnSer: 2.388 ± 0.199
2.515AsnThr: 2.515 ± 0.242
3.189AsnVal: 3.189 ± 0.203
0.618AsnTrp: 0.618 ± 0.108
0.998AsnTyr: 0.998 ± 0.101
0.0AsnXaa: 0.0 ± 0.0
Pro
6.393ProAla: 6.393 ± 0.492
1.208ProCys: 1.208 ± 0.16
3.372ProAsp: 3.372 ± 0.307
3.99ProGlu: 3.99 ± 0.341
2.29ProPhe: 2.29 ± 0.215
3.035ProGly: 3.035 ± 0.195
1.574ProHis: 1.574 ± 0.176
2.782ProIle: 2.782 ± 0.211
3.007ProLys: 3.007 ± 0.447
5.269ProLeu: 5.269 ± 0.366
1.082ProMet: 1.082 ± 0.137
2.107ProAsn: 2.107 ± 0.175
6.041ProPro: 6.041 ± 0.528
2.262ProGln: 2.262 ± 0.206
3.358ProArg: 3.358 ± 0.232
4.566ProSer: 4.566 ± 0.397
6.927ProThr: 6.927 ± 0.65
4.791ProVal: 4.791 ± 0.345
0.759ProTrp: 0.759 ± 0.106
1.335ProTyr: 1.335 ± 0.136
0.0ProXaa: 0.0 ± 0.0
Gln
2.543GlnAla: 2.543 ± 0.198
0.646GlnCys: 0.646 ± 0.098
1.672GlnAsp: 1.672 ± 0.174
1.419GlnGlu: 1.419 ± 0.117
1.517GlnPhe: 1.517 ± 0.153
1.616GlnGly: 1.616 ± 0.189
1.012GlnHis: 1.012 ± 0.126
1.7GlnIle: 1.7 ± 0.16
1.56GlnLys: 1.56 ± 0.15
4.032GlnLeu: 4.032 ± 0.311
0.983GlnMet: 0.983 ± 0.115
1.405GlnAsn: 1.405 ± 0.134
2.894GlnPro: 2.894 ± 0.298
1.897GlnGln: 1.897 ± 0.144
1.981GlnArg: 1.981 ± 0.197
2.669GlnSer: 2.669 ± 0.191
2.979GlnThr: 2.979 ± 0.282
2.29GlnVal: 2.29 ± 0.175
0.674GlnTrp: 0.674 ± 0.113
1.166GlnTyr: 1.166 ± 0.12
0.0GlnXaa: 0.0 ± 0.0
Arg
4.524ArgAla: 4.524 ± 0.276
1.236ArgCys: 1.236 ± 0.159
3.091ArgAsp: 3.091 ± 0.23
3.274ArgGlu: 3.274 ± 0.326
2.234ArgPhe: 2.234 ± 0.194
2.936ArgGly: 2.936 ± 0.219
1.391ArgHis: 1.391 ± 0.162
2.431ArgIle: 2.431 ± 0.204
2.979ArgLys: 2.979 ± 0.281
5.845ArgLeu: 5.845 ± 0.306
1.391ArgMet: 1.391 ± 0.134
2.178ArgAsn: 2.178 ± 0.159
3.217ArgPro: 3.217 ± 0.246
2.262ArgGln: 2.262 ± 0.172
4.622ArgArg: 4.622 ± 0.407
3.99ArgSer: 3.99 ± 0.352
3.836ArgThr: 3.836 ± 0.198
3.906ArgVal: 3.906 ± 0.262
1.18ArgTrp: 1.18 ± 0.139
1.602ArgTyr: 1.602 ± 0.144
0.0ArgXaa: 0.0 ± 0.0
Ser
5.873SerAla: 5.873 ± 0.345
0.955SerCys: 0.955 ± 0.126
4.468SerAsp: 4.468 ± 0.377
4.482SerGlu: 4.482 ± 0.369
2.122SerPhe: 2.122 ± 0.175
4.454SerGly: 4.454 ± 0.347
1.279SerHis: 1.279 ± 0.136
2.894SerIle: 2.894 ± 0.213
2.669SerLys: 2.669 ± 0.211
5.634SerLeu: 5.634 ± 0.296
1.56SerMet: 1.56 ± 0.137
2.388SerAsn: 2.388 ± 0.212
4.594SerPro: 4.594 ± 0.444
2.417SerGln: 2.417 ± 0.299
3.414SerArg: 3.414 ± 0.242
5.634SerSer: 5.634 ± 0.514
5.142SerThr: 5.142 ± 0.367
5.17SerVal: 5.17 ± 0.334
1.11SerTrp: 1.11 ± 0.128
1.784SerTyr: 1.784 ± 0.161
0.0SerXaa: 0.0 ± 0.0
Thr
6.983ThrAla: 6.983 ± 0.522
1.349ThrCys: 1.349 ± 0.194
4.327ThrAsp: 4.327 ± 0.289
3.85ThrGlu: 3.85 ± 0.217
3.063ThrPhe: 3.063 ± 0.206
3.962ThrGly: 3.962 ± 0.219
1.784ThrHis: 1.784 ± 0.163
3.091ThrIle: 3.091 ± 0.218
3.456ThrLys: 3.456 ± 0.241
6.14ThrLeu: 6.14 ± 0.313
1.658ThrMet: 1.658 ± 0.148
2.698ThrAsn: 2.698 ± 0.219
5.142ThrPro: 5.142 ± 0.501
2.374ThrGln: 2.374 ± 0.208
3.709ThrArg: 3.709 ± 0.206
4.777ThrSer: 4.777 ± 0.264
7.123ThrThr: 7.123 ± 1.034
6.041ThrVal: 6.041 ± 0.363
0.927ThrTrp: 0.927 ± 0.131
1.574ThrTyr: 1.574 ± 0.167
0.0ThrXaa: 0.0 ± 0.0
Val
5.985ValAla: 5.985 ± 0.352
1.616ValCys: 1.616 ± 0.196
4.159ValAsp: 4.159 ± 0.293
4.355ValGlu: 4.355 ± 0.268
2.712ValPhe: 2.712 ± 0.22
3.892ValGly: 3.892 ± 0.231
1.405ValHis: 1.405 ± 0.153
2.627ValIle: 2.627 ± 0.26
3.484ValLys: 3.484 ± 0.281
6.421ValLeu: 6.421 ± 0.295
2.037ValMet: 2.037 ± 0.206
2.796ValAsn: 2.796 ± 0.179
5.269ValPro: 5.269 ± 0.331
2.529ValGln: 2.529 ± 0.219
4.145ValArg: 4.145 ± 0.298
4.693ValSer: 4.693 ± 0.295
5.17ValThr: 5.17 ± 0.385
5.227ValVal: 5.227 ± 0.34
1.475ValTrp: 1.475 ± 0.169
2.122ValTyr: 2.122 ± 0.18
0.0ValXaa: 0.0 ± 0.0
Trp
1.293TrpAla: 1.293 ± 0.148
0.632TrpCys: 0.632 ± 0.117
0.871TrpAsp: 0.871 ± 0.118
0.787TrpGlu: 0.787 ± 0.112
0.745TrpPhe: 0.745 ± 0.112
1.18TrpGly: 1.18 ± 0.147
0.562TrpHis: 0.562 ± 0.095
0.885TrpIle: 0.885 ± 0.103
0.899TrpLys: 0.899 ± 0.134
1.644TrpLeu: 1.644 ± 0.134
0.309TrpMet: 0.309 ± 0.064
0.66TrpAsn: 0.66 ± 0.111
0.927TrpPro: 0.927 ± 0.13
0.506TrpGln: 0.506 ± 0.073
1.082TrpArg: 1.082 ± 0.142
1.25TrpSer: 1.25 ± 0.149
1.377TrpThr: 1.377 ± 0.149
0.983TrpVal: 0.983 ± 0.128
0.309TrpTrp: 0.309 ± 0.064
0.45TrpTyr: 0.45 ± 0.083
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.728TyrAla: 1.728 ± 0.157
0.534TyrCys: 0.534 ± 0.102
1.869TyrAsp: 1.869 ± 0.172
1.419TyrGlu: 1.419 ± 0.107
1.054TyrPhe: 1.054 ± 0.113
1.742TyrGly: 1.742 ± 0.167
0.787TyrHis: 0.787 ± 0.09
1.335TyrIle: 1.335 ± 0.14
1.503TyrLys: 1.503 ± 0.139
2.304TyrLeu: 2.304 ± 0.185
0.815TyrMet: 0.815 ± 0.118
1.25TyrAsn: 1.25 ± 0.172
1.068TyrPro: 1.068 ± 0.146
0.927TyrGln: 0.927 ± 0.119
1.531TyrArg: 1.531 ± 0.128
1.883TyrSer: 1.883 ± 0.176
2.332TyrThr: 2.332 ± 0.192
2.051TyrVal: 2.051 ± 0.196
0.393TyrTrp: 0.393 ± 0.081
1.026TyrTyr: 1.026 ± 0.107
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 129 proteins (71176 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski