Amino acid dipepetide frequency for Bombyx mori cytoplasmic polyhedrosis virus (BmCPV)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.065AlaAla: 5.065 ± 0.998
0.482AlaCys: 0.482 ± 0.235
5.667AlaAsp: 5.667 ± 0.676
3.015AlaGlu: 3.015 ± 0.499
2.653AlaPhe: 2.653 ± 0.481
3.015AlaGly: 3.015 ± 0.617
1.447AlaHis: 1.447 ± 0.395
3.738AlaIle: 3.738 ± 0.429
2.412AlaLys: 2.412 ± 0.591
8.32AlaLeu: 8.32 ± 1.019
1.568AlaMet: 1.568 ± 0.454
3.979AlaAsn: 3.979 ± 1.099
2.412AlaPro: 2.412 ± 0.511
2.894AlaGln: 2.894 ± 0.509
3.497AlaArg: 3.497 ± 0.627
5.306AlaSer: 5.306 ± 1.168
4.823AlaThr: 4.823 ± 0.599
5.065AlaVal: 5.065 ± 0.698
0.724AlaTrp: 0.724 ± 0.434
2.532AlaTyr: 2.532 ± 0.799
0.0AlaXaa: 0.0 ± 0.0
Cys
1.085CysAla: 1.085 ± 0.373
0.121CysCys: 0.121 ± 0.113
0.362CysAsp: 0.362 ± 0.191
0.241CysGlu: 0.241 ± 0.261
0.0CysPhe: 0.0 ± 0.0
0.482CysGly: 0.482 ± 0.235
0.121CysHis: 0.121 ± 0.115
0.121CysIle: 0.121 ± 0.13
0.241CysLys: 0.241 ± 0.23
0.482CysLeu: 0.482 ± 0.227
0.121CysMet: 0.121 ± 0.115
0.482CysAsn: 0.482 ± 0.285
0.482CysPro: 0.482 ± 0.285
0.482CysGln: 0.482 ± 0.217
0.362CysArg: 0.362 ± 0.228
0.603CysSer: 0.603 ± 0.327
0.603CysThr: 0.603 ± 0.207
0.362CysVal: 0.362 ± 0.23
0.0CysTrp: 0.0 ± 0.0
0.241CysTyr: 0.241 ± 0.155
0.0CysXaa: 0.0 ± 0.0
Asp
3.256AspAla: 3.256 ± 0.545
0.0AspCys: 0.0 ± 0.0
4.22AspAsp: 4.22 ± 1.032
4.944AspGlu: 4.944 ± 0.871
2.05AspPhe: 2.05 ± 0.447
3.015AspGly: 3.015 ± 0.606
1.568AspHis: 1.568 ± 0.447
4.703AspIle: 4.703 ± 0.426
1.326AspLys: 1.326 ± 0.42
5.065AspLeu: 5.065 ± 0.63
1.809AspMet: 1.809 ± 0.381
2.532AspAsn: 2.532 ± 0.428
2.412AspPro: 2.412 ± 0.585
1.809AspGln: 1.809 ± 0.693
2.412AspArg: 2.412 ± 0.504
3.135AspSer: 3.135 ± 0.57
5.426AspThr: 5.426 ± 1.12
5.909AspVal: 5.909 ± 0.712
0.362AspTrp: 0.362 ± 0.156
2.412AspTyr: 2.412 ± 0.357
0.0AspXaa: 0.0 ± 0.0
Glu
4.1GluAla: 4.1 ± 0.37
0.0GluCys: 0.0 ± 0.0
3.376GluAsp: 3.376 ± 0.551
1.688GluGlu: 1.688 ± 0.648
2.532GluPhe: 2.532 ± 0.357
2.412GluGly: 2.412 ± 0.478
1.326GluHis: 1.326 ± 0.299
3.859GluIle: 3.859 ± 0.924
2.412GluLys: 2.412 ± 0.414
5.306GluLeu: 5.306 ± 0.937
2.171GluMet: 2.171 ± 0.575
2.653GluAsn: 2.653 ± 0.752
1.809GluPro: 1.809 ± 0.524
3.135GluGln: 3.135 ± 0.411
3.256GluArg: 3.256 ± 0.467
3.859GluSer: 3.859 ± 0.802
3.256GluThr: 3.256 ± 0.531
4.1GluVal: 4.1 ± 0.642
0.121GluTrp: 0.121 ± 0.106
3.135GluTyr: 3.135 ± 0.648
0.0GluXaa: 0.0 ± 0.0
Phe
3.256PheAla: 3.256 ± 0.622
0.603PheCys: 0.603 ± 0.227
2.05PheAsp: 2.05 ± 0.616
2.05PheGlu: 2.05 ± 0.383
1.568PhePhe: 1.568 ± 0.471
1.326PheGly: 1.326 ± 0.402
0.724PheHis: 0.724 ± 0.212
1.929PheIle: 1.929 ± 0.489
2.653PheLys: 2.653 ± 0.469
3.015PheLeu: 3.015 ± 0.654
0.724PheMet: 0.724 ± 0.289
3.859PheAsn: 3.859 ± 0.469
1.568PhePro: 1.568 ± 0.387
1.206PheGln: 1.206 ± 0.275
1.929PheArg: 1.929 ± 0.266
3.015PheSer: 3.015 ± 0.551
3.135PheThr: 3.135 ± 0.584
2.171PheVal: 2.171 ± 0.394
0.121PheTrp: 0.121 ± 0.113
0.965PheTyr: 0.965 ± 0.412
0.0PheXaa: 0.0 ± 0.0
Gly
3.738GlyAla: 3.738 ± 0.662
0.362GlyCys: 0.362 ± 0.186
3.256GlyAsp: 3.256 ± 0.532
3.135GlyGlu: 3.135 ± 0.454
1.085GlyPhe: 1.085 ± 0.456
2.05GlyGly: 2.05 ± 0.49
1.326GlyHis: 1.326 ± 0.452
3.497GlyIle: 3.497 ± 0.54
2.05GlyLys: 2.05 ± 0.583
3.497GlyLeu: 3.497 ± 0.659
1.326GlyMet: 1.326 ± 0.536
3.015GlyAsn: 3.015 ± 0.639
1.447GlyPro: 1.447 ± 0.342
1.929GlyGln: 1.929 ± 0.377
2.653GlyArg: 2.653 ± 0.425
2.773GlySer: 2.773 ± 0.43
3.497GlyThr: 3.497 ± 0.718
3.618GlyVal: 3.618 ± 0.643
0.121GlyTrp: 0.121 ± 0.113
2.653GlyTyr: 2.653 ± 0.368
0.0GlyXaa: 0.0 ± 0.0
His
2.412HisAla: 2.412 ± 0.332
0.121HisCys: 0.121 ± 0.113
1.085HisAsp: 1.085 ± 0.335
1.929HisGlu: 1.929 ± 0.448
1.085HisPhe: 1.085 ± 0.223
0.724HisGly: 0.724 ± 0.321
0.241HisHis: 0.241 ± 0.226
1.568HisIle: 1.568 ± 0.33
1.809HisLys: 1.809 ± 0.401
2.894HisLeu: 2.894 ± 0.411
0.482HisMet: 0.482 ± 0.199
1.568HisAsn: 1.568 ± 0.406
1.206HisPro: 1.206 ± 0.285
0.965HisGln: 0.965 ± 0.436
1.085HisArg: 1.085 ± 0.196
2.291HisSer: 2.291 ± 0.516
1.809HisThr: 1.809 ± 0.442
1.929HisVal: 1.929 ± 0.277
0.241HisTrp: 0.241 ± 0.142
0.965HisTyr: 0.965 ± 0.405
0.0HisXaa: 0.0 ± 0.0
Ile
4.341IleAla: 4.341 ± 0.784
0.482IleCys: 0.482 ± 0.184
5.426IleAsp: 5.426 ± 0.714
3.376IleGlu: 3.376 ± 0.324
2.412IlePhe: 2.412 ± 0.479
3.376IleGly: 3.376 ± 0.74
1.447IleHis: 1.447 ± 0.367
3.376IleIle: 3.376 ± 0.564
3.859IleLys: 3.859 ± 1.007
5.065IleLeu: 5.065 ± 0.878
2.171IleMet: 2.171 ± 0.379
4.462IleAsn: 4.462 ± 0.725
4.1IlePro: 4.1 ± 0.631
1.688IleGln: 1.688 ± 0.366
4.22IleArg: 4.22 ± 0.739
5.909IleSer: 5.909 ± 0.825
5.185IleThr: 5.185 ± 0.835
4.1IleVal: 4.1 ± 0.742
0.482IleTrp: 0.482 ± 0.284
2.412IleTyr: 2.412 ± 0.388
0.0IleXaa: 0.0 ± 0.0
Lys
1.809LysAla: 1.809 ± 0.398
0.482LysCys: 0.482 ± 0.239
1.326LysAsp: 1.326 ± 0.352
2.291LysGlu: 2.291 ± 0.782
0.965LysPhe: 0.965 ± 0.477
2.773LysGly: 2.773 ± 0.351
1.447LysHis: 1.447 ± 0.484
2.894LysIle: 2.894 ± 0.419
2.532LysLys: 2.532 ± 0.767
4.462LysLeu: 4.462 ± 0.895
1.447LysMet: 1.447 ± 0.415
1.809LysAsn: 1.809 ± 0.505
3.015LysPro: 3.015 ± 1.09
2.412LysGln: 2.412 ± 0.68
2.532LysArg: 2.532 ± 0.565
2.532LysSer: 2.532 ± 0.642
2.773LysThr: 2.773 ± 0.576
2.05LysVal: 2.05 ± 0.367
0.603LysTrp: 0.603 ± 0.247
2.773LysTyr: 2.773 ± 0.454
0.0LysXaa: 0.0 ± 0.0
Leu
5.426LeuAla: 5.426 ± 0.696
1.206LeuCys: 1.206 ± 0.347
4.823LeuAsp: 4.823 ± 0.723
4.462LeuGlu: 4.462 ± 0.627
4.341LeuPhe: 4.341 ± 0.877
4.341LeuGly: 4.341 ± 1.13
3.376LeuHis: 3.376 ± 0.868
5.426LeuIle: 5.426 ± 1.156
3.618LeuLys: 3.618 ± 0.601
7.597LeuLeu: 7.597 ± 1.118
2.894LeuMet: 2.894 ± 0.212
3.618LeuAsn: 3.618 ± 0.578
3.618LeuPro: 3.618 ± 0.764
3.015LeuGln: 3.015 ± 0.457
6.27LeuArg: 6.27 ± 1.062
10.008LeuSer: 10.008 ± 0.436
5.306LeuThr: 5.306 ± 0.689
5.788LeuVal: 5.788 ± 0.516
0.241LeuTrp: 0.241 ± 0.226
3.979LeuTyr: 3.979 ± 0.85
0.0LeuXaa: 0.0 ± 0.0
Met
1.085MetAla: 1.085 ± 0.314
0.121MetCys: 0.121 ± 0.115
1.809MetAsp: 1.809 ± 0.319
1.206MetGlu: 1.206 ± 0.379
0.965MetPhe: 0.965 ± 0.217
0.241MetGly: 0.241 ± 0.146
1.085MetHis: 1.085 ± 0.245
2.171MetIle: 2.171 ± 0.415
1.085MetLys: 1.085 ± 0.361
2.532MetLeu: 2.532 ± 0.422
1.447MetMet: 1.447 ± 0.44
2.05MetAsn: 2.05 ± 0.513
1.326MetPro: 1.326 ± 0.366
0.844MetGln: 0.844 ± 0.315
2.171MetArg: 2.171 ± 0.487
2.171MetSer: 2.171 ± 0.268
3.618MetThr: 3.618 ± 0.588
1.326MetVal: 1.326 ± 0.428
0.241MetTrp: 0.241 ± 0.142
1.447MetTyr: 1.447 ± 0.295
0.0MetXaa: 0.0 ± 0.0
Asn
3.859AsnAla: 3.859 ± 0.72
0.362AsnCys: 0.362 ± 0.227
4.1AsnAsp: 4.1 ± 0.891
3.015AsnGlu: 3.015 ± 0.861
1.326AsnPhe: 1.326 ± 0.434
2.412AsnGly: 2.412 ± 0.471
1.809AsnHis: 1.809 ± 0.374
4.341AsnIle: 4.341 ± 0.789
1.688AsnLys: 1.688 ± 0.407
3.015AsnLeu: 3.015 ± 0.576
1.809AsnMet: 1.809 ± 0.462
3.497AsnAsn: 3.497 ± 0.73
2.05AsnPro: 2.05 ± 0.368
1.809AsnGln: 1.809 ± 0.367
3.497AsnArg: 3.497 ± 0.517
4.462AsnSer: 4.462 ± 1.034
4.1AsnThr: 4.1 ± 0.554
5.667AsnVal: 5.667 ± 0.727
0.844AsnTrp: 0.844 ± 0.237
2.532AsnTyr: 2.532 ± 0.485
0.0AsnXaa: 0.0 ± 0.0
Pro
3.738ProAla: 3.738 ± 0.706
0.121ProCys: 0.121 ± 0.115
2.05ProAsp: 2.05 ± 1.102
2.291ProGlu: 2.291 ± 0.493
1.929ProPhe: 1.929 ± 0.603
1.326ProGly: 1.326 ± 0.341
1.326ProHis: 1.326 ± 0.452
3.135ProIle: 3.135 ± 0.803
2.05ProLys: 2.05 ± 0.501
3.979ProLeu: 3.979 ± 0.641
1.326ProMet: 1.326 ± 0.372
2.653ProAsn: 2.653 ± 0.696
1.206ProPro: 1.206 ± 0.379
1.447ProGln: 1.447 ± 0.361
2.532ProArg: 2.532 ± 0.457
4.1ProSer: 4.1 ± 0.588
3.256ProThr: 3.256 ± 0.757
3.376ProVal: 3.376 ± 0.556
0.362ProTrp: 0.362 ± 0.238
1.447ProTyr: 1.447 ± 0.33
0.0ProXaa: 0.0 ± 0.0
Gln
2.291GlnAla: 2.291 ± 0.538
0.482GlnCys: 0.482 ± 0.176
1.447GlnAsp: 1.447 ± 0.317
1.809GlnGlu: 1.809 ± 0.465
1.809GlnPhe: 1.809 ± 0.491
2.412GlnGly: 2.412 ± 0.655
1.206GlnHis: 1.206 ± 0.259
3.738GlnIle: 3.738 ± 0.715
1.447GlnLys: 1.447 ± 0.292
4.1GlnLeu: 4.1 ± 0.756
0.724GlnMet: 0.724 ± 0.261
1.447GlnAsn: 1.447 ± 0.37
0.844GlnPro: 0.844 ± 0.347
1.929GlnGln: 1.929 ± 0.63
3.015GlnArg: 3.015 ± 0.51
3.135GlnSer: 3.135 ± 0.523
2.773GlnThr: 2.773 ± 0.552
1.809GlnVal: 1.809 ± 0.478
0.362GlnTrp: 0.362 ± 0.16
1.326GlnTyr: 1.326 ± 0.442
0.0GlnXaa: 0.0 ± 0.0
Arg
4.944ArgAla: 4.944 ± 0.878
0.362ArgCys: 0.362 ± 0.184
2.653ArgAsp: 2.653 ± 0.352
3.256ArgGlu: 3.256 ± 0.377
2.291ArgPhe: 2.291 ± 0.413
2.291ArgGly: 2.291 ± 0.645
1.326ArgHis: 1.326 ± 0.458
4.823ArgIle: 4.823 ± 0.718
2.05ArgLys: 2.05 ± 0.501
7.476ArgLeu: 7.476 ± 0.62
1.568ArgMet: 1.568 ± 0.369
3.015ArgAsn: 3.015 ± 0.645
2.412ArgPro: 2.412 ± 0.529
2.532ArgGln: 2.532 ± 0.547
3.738ArgArg: 3.738 ± 0.877
4.341ArgSer: 4.341 ± 0.644
4.341ArgThr: 4.341 ± 0.415
3.859ArgVal: 3.859 ± 0.865
0.603ArgTrp: 0.603 ± 0.318
2.171ArgTyr: 2.171 ± 0.381
0.0ArgXaa: 0.0 ± 0.0
Ser
4.1SerAla: 4.1 ± 0.823
0.603SerCys: 0.603 ± 0.264
5.185SerAsp: 5.185 ± 0.676
5.547SerGlu: 5.547 ± 0.65
2.412SerPhe: 2.412 ± 0.656
4.22SerGly: 4.22 ± 0.942
1.929SerHis: 1.929 ± 0.583
5.306SerIle: 5.306 ± 0.447
3.015SerLys: 3.015 ± 0.699
5.667SerLeu: 5.667 ± 0.776
2.291SerMet: 2.291 ± 0.449
4.462SerAsn: 4.462 ± 0.653
3.135SerPro: 3.135 ± 0.434
2.894SerGln: 2.894 ± 0.596
5.185SerArg: 5.185 ± 0.871
5.788SerSer: 5.788 ± 0.632
6.994SerThr: 6.994 ± 0.906
5.065SerVal: 5.065 ± 0.866
0.724SerTrp: 0.724 ± 0.313
3.376SerTyr: 3.376 ± 0.492
0.0SerXaa: 0.0 ± 0.0
Thr
5.065ThrAla: 5.065 ± 0.639
0.603ThrCys: 0.603 ± 0.225
3.376ThrAsp: 3.376 ± 0.83
3.497ThrGlu: 3.497 ± 0.435
3.376ThrPhe: 3.376 ± 0.66
3.497ThrGly: 3.497 ± 0.608
1.809ThrHis: 1.809 ± 0.431
5.667ThrIle: 5.667 ± 0.823
3.618ThrLys: 3.618 ± 0.828
6.632ThrLeu: 6.632 ± 0.671
1.688ThrMet: 1.688 ± 0.524
3.618ThrAsn: 3.618 ± 0.696
4.1ThrPro: 4.1 ± 0.95
2.894ThrGln: 2.894 ± 0.566
4.1ThrArg: 4.1 ± 0.631
5.185ThrSer: 5.185 ± 0.679
4.944ThrThr: 4.944 ± 0.651
4.944ThrVal: 4.944 ± 0.622
0.844ThrTrp: 0.844 ± 0.347
4.582ThrTyr: 4.582 ± 0.554
0.0ThrXaa: 0.0 ± 0.0
Val
5.667ValAla: 5.667 ± 0.902
0.362ValCys: 0.362 ± 0.167
3.256ValAsp: 3.256 ± 0.753
3.859ValGlu: 3.859 ± 0.639
3.135ValPhe: 3.135 ± 0.611
3.738ValGly: 3.738 ± 0.714
1.206ValHis: 1.206 ± 0.285
4.582ValIle: 4.582 ± 0.575
3.015ValLys: 3.015 ± 0.565
6.632ValLeu: 6.632 ± 0.489
1.568ValMet: 1.568 ± 0.394
4.462ValAsn: 4.462 ± 0.725
3.256ValPro: 3.256 ± 0.507
2.412ValGln: 2.412 ± 0.644
4.582ValArg: 4.582 ± 0.56
6.391ValSer: 6.391 ± 0.784
3.979ValThr: 3.979 ± 0.557
4.1ValVal: 4.1 ± 1.144
0.603ValTrp: 0.603 ± 0.282
2.532ValTyr: 2.532 ± 0.405
0.0ValXaa: 0.0 ± 0.0
Trp
0.121TrpAla: 0.121 ± 0.131
0.0TrpCys: 0.0 ± 0.0
0.241TrpAsp: 0.241 ± 0.141
0.482TrpGlu: 0.482 ± 0.238
0.241TrpPhe: 0.241 ± 0.159
0.121TrpGly: 0.121 ± 0.113
0.724TrpHis: 0.724 ± 0.426
0.121TrpIle: 0.121 ± 0.106
0.362TrpLys: 0.362 ± 0.244
0.603TrpLeu: 0.603 ± 0.258
0.603TrpMet: 0.603 ± 0.279
0.482TrpAsn: 0.482 ± 0.199
0.482TrpPro: 0.482 ± 0.159
0.362TrpGln: 0.362 ± 0.216
0.482TrpArg: 0.482 ± 0.24
0.844TrpSer: 0.844 ± 0.222
0.482TrpThr: 0.482 ± 0.269
0.603TrpVal: 0.603 ± 0.24
0.121TrpTrp: 0.121 ± 0.106
0.482TrpTyr: 0.482 ± 0.247
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.256TyrAla: 3.256 ± 0.669
0.121TyrCys: 0.121 ± 0.109
2.653TyrAsp: 2.653 ± 0.611
2.412TyrGlu: 2.412 ± 0.504
1.688TyrPhe: 1.688 ± 0.505
3.256TyrGly: 3.256 ± 0.657
0.965TyrHis: 0.965 ± 0.279
2.894TyrIle: 2.894 ± 0.79
1.688TyrLys: 1.688 ± 0.5
3.015TyrLeu: 3.015 ± 0.422
1.085TyrMet: 1.085 ± 0.356
2.532TyrAsn: 2.532 ± 0.528
2.773TyrPro: 2.773 ± 0.713
1.447TyrGln: 1.447 ± 0.186
2.532TyrArg: 2.532 ± 0.718
2.171TyrSer: 2.171 ± 0.556
3.738TyrThr: 3.738 ± 0.795
3.497TyrVal: 3.497 ± 0.448
0.241TyrTrp: 0.241 ± 0.17
1.929TyrTyr: 1.929 ± 0.553
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 11 proteins (8294 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski