Amino acid dipepetide frequency for Sulfitobacter marinus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	15.059AlaAla: 15.059 ± 0.179	1.087AlaCys: 1.087 ± 0.033	7.161AlaAsp: 7.161 ± 0.089	7.145AlaGlu: 7.145 ± 0.118	4.235AlaPhe: 4.235 ± 0.071	9.745AlaGly: 9.745 ± 0.104	2.259AlaHis: 2.259 ± 0.047	6.165AlaIle: 6.165 ± 0.079	4.384AlaLys: 4.384 ± 0.073	12.687AlaLeu: 12.687 ± 0.147	3.781AlaMet: 3.781 ± 0.064	2.96AlaAsn: 2.96 ± 0.049	5.357AlaPro: 5.357 ± 0.079	4.965AlaGln: 4.965 ± 0.074	7.232AlaArg: 7.232 ± 0.093	5.777AlaSer: 5.777 ± 0.081	5.86AlaThr: 5.86 ± 0.092	8.079AlaVal: 8.079 ± 0.099	1.36AlaTrp: 1.36 ± 0.039	2.503AlaTyr: 2.503 ± 0.042	0.0AlaXaa: 0.0 ± 0.0
Cys	1.109CysAla: 1.109 ± 0.031	0.107CysCys: 0.107 ± 0.01	0.649CysAsp: 0.649 ± 0.026	0.446CysGlu: 0.446 ± 0.024	0.361CysPhe: 0.361 ± 0.02	0.903CysGly: 0.903 ± 0.029	0.246CysHis: 0.246 ± 0.015	0.496CysIle: 0.496 ± 0.02	0.257CysLys: 0.257 ± 0.016	0.825CysLeu: 0.825 ± 0.028	0.188CysMet: 0.188 ± 0.013	0.246CysAsn: 0.246 ± 0.016	0.46CysPro: 0.46 ± 0.023	0.238CysGln: 0.238 ± 0.016	0.462CysArg: 0.462 ± 0.02	0.447CysSer: 0.447 ± 0.02	0.483CysThr: 0.483 ± 0.021	0.668CysVal: 0.668 ± 0.027	0.109CysTrp: 0.109 ± 0.01	0.224CysTyr: 0.224 ± 0.014	0.0CysXaa: 0.0 ± 0.0
Asp	7.792AspAla: 7.792 ± 0.109	0.503AspCys: 0.503 ± 0.022	3.727AspAsp: 3.727 ± 0.071	3.383AspGlu: 3.383 ± 0.062	2.279AspPhe: 2.279 ± 0.054	5.542AspGly: 5.542 ± 0.091	1.482AspHis: 1.482 ± 0.038	3.642AspIle: 3.642 ± 0.066	1.956AspLys: 1.956 ± 0.044	6.32AspLeu: 6.32 ± 0.075	1.956AspMet: 1.956 ± 0.046	1.48AspAsn: 1.48 ± 0.039	3.435AspPro: 3.435 ± 0.054	2.278AspGln: 2.278 ± 0.05	3.753AspArg: 3.753 ± 0.06	2.292AspSer: 2.292 ± 0.047	3.329AspThr: 3.329 ± 0.059	4.822AspVal: 4.822 ± 0.071	1.104AspTrp: 1.104 ± 0.036	1.533AspTyr: 1.533 ± 0.037	0.0AspXaa: 0.0 ± 0.0
Glu	6.774GluAla: 6.774 ± 0.105	0.36GluCys: 0.36 ± 0.018	3.107GluAsp: 3.107 ± 0.055	2.933GluGlu: 2.933 ± 0.064	1.776GluPhe: 1.776 ± 0.039	4.182GluGly: 4.182 ± 0.066	1.141GluHis: 1.141 ± 0.034	3.553GluIle: 3.553 ± 0.059	2.384GluLys: 2.384 ± 0.062	4.906GluLeu: 4.906 ± 0.075	1.903GluMet: 1.903 ± 0.038	2.099GluAsn: 2.099 ± 0.043	2.136GluPro: 2.136 ± 0.046	1.959GluGln: 1.959 ± 0.047	3.522GluArg: 3.522 ± 0.063	1.976GluSer: 1.976 ± 0.041	3.797GluThr: 3.797 ± 0.062	3.997GluVal: 3.997 ± 0.069	0.662GluTrp: 0.662 ± 0.027	1.124GluTyr: 1.124 ± 0.033	0.0GluXaa: 0.0 ± 0.0
Phe	4.362PheAla: 4.362 ± 0.069	0.451PheCys: 0.451 ± 0.02	3.032PheAsp: 3.032 ± 0.059	2.302PheGlu: 2.302 ± 0.044	1.495PhePhe: 1.495 ± 0.044	3.773PheGly: 3.773 ± 0.063	0.752PheHis: 0.752 ± 0.027	1.925PheIle: 1.925 ± 0.052	1.226PheLys: 1.226 ± 0.035	3.393PheLeu: 3.393 ± 0.071	0.97PheMet: 0.97 ± 0.033	1.216PheAsn: 1.216 ± 0.032	1.471PhePro: 1.471 ± 0.036	1.127PheGln: 1.127 ± 0.033	1.82PheArg: 1.82 ± 0.042	2.262PheSer: 2.262 ± 0.05	2.236PheThr: 2.236 ± 0.043	2.721PheVal: 2.721 ± 0.054	0.57PheTrp: 0.57 ± 0.023	0.978PheTyr: 0.978 ± 0.033	0.0PheXaa: 0.0 ± 0.0
Gly	9.226GlyAla: 9.226 ± 0.114	0.875GlyCys: 0.875 ± 0.031	4.878GlyAsp: 4.878 ± 0.077	4.052GlyGlu: 4.052 ± 0.068	3.742GlyPhe: 3.742 ± 0.059	7.193GlyGly: 7.193 ± 0.108	1.891GlyHis: 1.891 ± 0.045	4.713GlyIle: 4.713 ± 0.078	3.463GlyLys: 3.463 ± 0.068	8.674GlyLeu: 8.674 ± 0.1	2.769GlyMet: 2.769 ± 0.055	2.295GlyAsn: 2.295 ± 0.063	3.519GlyPro: 3.519 ± 0.056	3.292GlyGln: 3.292 ± 0.06	4.945GlyArg: 4.945 ± 0.073	4.335GlySer: 4.335 ± 0.064	4.877GlyThr: 4.877 ± 0.069	6.38GlyVal: 6.38 ± 0.082	1.405GlyTrp: 1.405 ± 0.039	2.342GlyTyr: 2.342 ± 0.045	0.0GlyXaa: 0.0 ± 0.0
His	2.286HisAla: 2.286 ± 0.046	0.219HisCys: 0.219 ± 0.014	1.318HisAsp: 1.318 ± 0.036	1.013HisGlu: 1.013 ± 0.031	0.889HisPhe: 0.889 ± 0.028	1.86HisGly: 1.86 ± 0.045	0.557HisHis: 0.557 ± 0.023	1.136HisIle: 1.136 ± 0.039	0.612HisLys: 0.612 ± 0.02	2.066HisLeu: 2.066 ± 0.045	0.565HisMet: 0.565 ± 0.021	0.536HisAsn: 0.536 ± 0.023	1.327HisPro: 1.327 ± 0.033	0.679HisGln: 0.679 ± 0.029	1.153HisArg: 1.153 ± 0.037	1.028HisSer: 1.028 ± 0.029	0.917HisThr: 0.917 ± 0.031	1.52HisVal: 1.52 ± 0.037	0.325HisTrp: 0.325 ± 0.017	0.549HisTyr: 0.549 ± 0.022	0.0HisXaa: 0.0 ± 0.0
Ile	7.202IleAla: 7.202 ± 0.087	0.691IleCys: 0.691 ± 0.026	3.898IleAsp: 3.898 ± 0.057	3.554IleGlu: 3.554 ± 0.054	1.957IlePhe: 1.957 ± 0.055	5.171IleGly: 5.171 ± 0.079	0.932IleHis: 0.932 ± 0.031	2.836IleIle: 2.836 ± 0.049	2.029IleLys: 2.029 ± 0.041	5.078IleLeu: 5.078 ± 0.087	1.331IleMet: 1.331 ± 0.04	1.733IleAsn: 1.733 ± 0.043	2.48IlePro: 2.48 ± 0.05	1.408IleGln: 1.408 ± 0.04	2.967IleArg: 2.967 ± 0.049	3.518IleSer: 3.518 ± 0.068	3.399IleThr: 3.399 ± 0.061	4.034IleVal: 4.034 ± 0.066	0.838IleTrp: 0.838 ± 0.028	1.3IleTyr: 1.3 ± 0.035	0.0IleXaa: 0.0 ± 0.0
Lys	4.231LysAla: 4.231 ± 0.068	0.222LysCys: 0.222 ± 0.014	2.134LysAsp: 2.134 ± 0.05	1.671LysGlu: 1.671 ± 0.042	1.152LysPhe: 1.152 ± 0.033	3.027LysGly: 3.027 ± 0.06	0.743LysHis: 0.743 ± 0.028	2.124LysIle: 2.124 ± 0.045	1.48LysLys: 1.48 ± 0.044	3.48LysLeu: 3.48 ± 0.052	1.162LysMet: 1.162 ± 0.036	1.086LysAsn: 1.086 ± 0.036	2.07LysPro: 2.07 ± 0.05	1.152LysGln: 1.152 ± 0.032	2.503LysArg: 2.503 ± 0.049	2.169LysSer: 2.169 ± 0.042	2.407LysThr: 2.407 ± 0.048	2.48LysVal: 2.48 ± 0.05	0.452LysTrp: 0.452 ± 0.019	0.786LysTyr: 0.786 ± 0.032	0.0LysXaa: 0.0 ± 0.0
Leu	11.781LeuAla: 11.781 ± 0.125	0.978LeuCys: 0.978 ± 0.029	5.839LeuAsp: 5.839 ± 0.081	5.136LeuGlu: 5.136 ± 0.082	3.609LeuPhe: 3.609 ± 0.059	8.087LeuGly: 8.087 ± 0.1	1.88LeuHis: 1.88 ± 0.045	5.636LeuIle: 5.636 ± 0.084	3.434LeuLys: 3.434 ± 0.055	8.664LeuLeu: 8.664 ± 0.136	2.902LeuMet: 2.902 ± 0.052	3.035LeuAsn: 3.035 ± 0.054	5.296LeuPro: 5.296 ± 0.073	2.829LeuGln: 2.829 ± 0.057	6.526LeuArg: 6.526 ± 0.077	6.648LeuSer: 6.648 ± 0.087	6.043LeuThr: 6.043 ± 0.079	6.527LeuVal: 6.527 ± 0.085	1.258LeuTrp: 1.258 ± 0.042	1.985LeuTyr: 1.985 ± 0.042	0.0LeuXaa: 0.0 ± 0.0
Met	3.576MetAla: 3.576 ± 0.062	0.214MetCys: 0.214 ± 0.014	1.588MetAsp: 1.588 ± 0.038	1.306MetGlu: 1.306 ± 0.036	0.919MetPhe: 0.919 ± 0.036	2.585MetGly: 2.585 ± 0.056	0.513MetHis: 0.513 ± 0.024	1.887MetIle: 1.887 ± 0.041	1.233MetLys: 1.233 ± 0.038	2.797MetLeu: 2.797 ± 0.052	0.949MetMet: 0.949 ± 0.035	1.034MetAsn: 1.034 ± 0.031	1.603MetPro: 1.603 ± 0.039	1.155MetGln: 1.155 ± 0.033	1.928MetArg: 1.928 ± 0.037	1.887MetSer: 1.887 ± 0.041	2.34MetThr: 2.34 ± 0.045	2.013MetVal: 2.013 ± 0.039	0.275MetTrp: 0.275 ± 0.017	0.398MetTyr: 0.398 ± 0.02	0.0MetXaa: 0.0 ± 0.0
Asn	3.636AsnAla: 3.636 ± 0.057	0.293AsnCys: 0.293 ± 0.017	1.703AsnAsp: 1.703 ± 0.049	1.316AsnGlu: 1.316 ± 0.036	1.089AsnPhe: 1.089 ± 0.032	2.688AsnGly: 2.688 ± 0.054	0.562AsnHis: 0.562 ± 0.025	1.679AsnIle: 1.679 ± 0.045	0.925AsnLys: 0.925 ± 0.03	2.761AsnLeu: 2.761 ± 0.06	0.864AsnMet: 0.864 ± 0.033	0.874AsnAsn: 0.874 ± 0.03	2.034AsnPro: 2.034 ± 0.037	0.854AsnGln: 0.854 ± 0.027	1.755AsnArg: 1.755 ± 0.037	1.343AsnSer: 1.343 ± 0.04	1.624AsnThr: 1.624 ± 0.042	2.102AsnVal: 2.102 ± 0.047	0.475AsnTrp: 0.475 ± 0.024	0.719AsnTyr: 0.719 ± 0.026	0.0AsnXaa: 0.0 ± 0.0
Pro	5.261ProAla: 5.261 ± 0.082	0.349ProCys: 0.349 ± 0.02	3.904ProAsp: 3.904 ± 0.067	3.458ProGlu: 3.458 ± 0.066	2.029ProPhe: 2.029 ± 0.046	3.798ProGly: 3.798 ± 0.061	1.0ProHis: 1.0 ± 0.028	2.484ProIle: 2.484 ± 0.048	1.969ProLys: 1.969 ± 0.048	4.524ProLeu: 4.524 ± 0.061	1.366ProMet: 1.366 ± 0.034	1.526ProAsn: 1.526 ± 0.045	1.986ProPro: 1.986 ± 0.049	1.822ProGln: 1.822 ± 0.047	2.409ProArg: 2.409 ± 0.05	2.65ProSer: 2.65 ± 0.046	2.514ProThr: 2.514 ± 0.054	3.978ProVal: 3.978 ± 0.068	0.584ProTrp: 0.584 ± 0.026	1.166ProTyr: 1.166 ± 0.034	0.0ProXaa: 0.0 ± 0.0
Gln	4.167GlnAla: 4.167 ± 0.065	0.202GlnCys: 0.202 ± 0.014	1.965GlnAsp: 1.965 ± 0.039	1.623GlnGlu: 1.623 ± 0.048	1.207GlnPhe: 1.207 ± 0.032	2.813GlnGly: 2.813 ± 0.054	0.698GlnHis: 0.698 ± 0.026	2.382GlnIle: 2.382 ± 0.049	1.28GlnLys: 1.28 ± 0.036	3.125GlnLeu: 3.125 ± 0.056	1.249GlnMet: 1.249 ± 0.03	1.101GlnAsn: 1.101 ± 0.036	1.6GlnPro: 1.6 ± 0.038	1.279GlnGln: 1.279 ± 0.038	2.161GlnArg: 2.161 ± 0.049	2.082GlnSer: 2.082 ± 0.049	2.183GlnThr: 2.183 ± 0.049	2.426GlnVal: 2.426 ± 0.049	0.432GlnTrp: 0.432 ± 0.019	0.674GlnTyr: 0.674 ± 0.025	0.0GlnXaa: 0.0 ± 0.0
Arg	6.981ArgAla: 6.981 ± 0.092	0.425ArgCys: 0.425 ± 0.02	3.974ArgAsp: 3.974 ± 0.068	3.233ArgGlu: 3.233 ± 0.062	2.463ArgPhe: 2.463 ± 0.047	4.156ArgGly: 4.156 ± 0.065	1.28ArgHis: 1.28 ± 0.035	3.511ArgIle: 3.511 ± 0.058	2.446ArgLys: 2.446 ± 0.049	6.166ArgLeu: 6.166 ± 0.091	1.908ArgMet: 1.908 ± 0.036	1.779ArgAsn: 1.779 ± 0.039	2.779ArgPro: 2.779 ± 0.055	2.146ArgGln: 2.146 ± 0.046	3.871ArgArg: 3.871 ± 0.067	3.121ArgSer: 3.121 ± 0.052	2.677ArgThr: 2.677 ± 0.055	4.276ArgVal: 4.276 ± 0.069	0.809ArgTrp: 0.809 ± 0.026	1.414ArgTyr: 1.414 ± 0.037	0.0ArgXaa: 0.0 ± 0.0
Ser	5.859SerAla: 5.859 ± 0.076	0.403SerCys: 0.403 ± 0.024	3.575SerAsp: 3.575 ± 0.06	2.826SerGlu: 2.826 ± 0.051	2.439SerPhe: 2.439 ± 0.047	5.355SerGly: 5.355 ± 0.091	1.139SerHis: 1.139 ± 0.033	2.839SerIle: 2.839 ± 0.058	1.914SerLys: 1.914 ± 0.039	5.196SerLeu: 5.196 ± 0.078	1.612SerMet: 1.612 ± 0.044	1.575SerAsn: 1.575 ± 0.039	2.52SerPro: 2.52 ± 0.047	1.781SerGln: 1.781 ± 0.048	3.039SerArg: 3.039 ± 0.057	2.879SerSer: 2.879 ± 0.062	2.745SerThr: 2.745 ± 0.047	3.965SerVal: 3.965 ± 0.062	0.687SerTrp: 0.687 ± 0.024	1.402SerTyr: 1.402 ± 0.035	0.0SerXaa: 0.0 ± 0.0
Thr	6.289ThrAla: 6.289 ± 0.087	0.509ThrCys: 0.509 ± 0.022	3.502ThrAsp: 3.502 ± 0.058	2.828ThrGlu: 2.828 ± 0.055	1.992ThrPhe: 1.992 ± 0.042	5.242ThrGly: 5.242 ± 0.076	1.22ThrHis: 1.22 ± 0.037	2.946ThrIle: 2.946 ± 0.053	1.931ThrLys: 1.931 ± 0.043	6.286ThrLeu: 6.286 ± 0.08	1.503ThrMet: 1.503 ± 0.034	1.497ThrAsn: 1.497 ± 0.04	3.521ThrPro: 3.521 ± 0.053	2.007ThrGln: 2.007 ± 0.044	3.245ThrArg: 3.245 ± 0.049	3.039ThrSer: 3.039 ± 0.048	3.053ThrThr: 3.053 ± 0.057	4.387ThrVal: 4.387 ± 0.065	0.641ThrTrp: 0.641 ± 0.023	1.362ThrTyr: 1.362 ± 0.043	0.0ThrXaa: 0.0 ± 0.0
Val	8.327ValAla: 8.327 ± 0.092	0.664ValCys: 0.664 ± 0.025	4.205ValAsp: 4.205 ± 0.062	4.248ValGlu: 4.248 ± 0.067	2.94ValPhe: 2.94 ± 0.049	5.601ValGly: 5.601 ± 0.074	1.35ValHis: 1.35 ± 0.038	4.573ValIle: 4.573 ± 0.073	2.419ValLys: 2.419 ± 0.051	7.28ValLeu: 7.28 ± 0.092	2.253ValMet: 2.253 ± 0.051	2.098ValAsn: 2.098 ± 0.043	3.442ValPro: 3.442 ± 0.06	2.331ValGln: 2.331 ± 0.042	3.739ValArg: 3.739 ± 0.06	4.333ValSer: 4.333 ± 0.065	4.586ValThr: 4.586 ± 0.067	5.573ValVal: 5.573 ± 0.077	0.932ValTrp: 0.932 ± 0.029	1.557ValTyr: 1.557 ± 0.044	0.0ValXaa: 0.0 ± 0.0
Trp	1.296TrpAla: 1.296 ± 0.037	0.132TrpCys: 0.132 ± 0.011	0.777TrpAsp: 0.777 ± 0.027	0.58TrpGlu: 0.58 ± 0.022	0.546TrpPhe: 0.546 ± 0.021	1.027TrpGly: 1.027 ± 0.037	0.366TrpHis: 0.366 ± 0.018	0.731TrpIle: 0.731 ± 0.026	0.483TrpLys: 0.483 ± 0.021	1.513TrpLeu: 1.513 ± 0.035	0.436TrpMet: 0.436 ± 0.02	0.448TrpAsn: 0.448 ± 0.022	0.649TrpPro: 0.649 ± 0.025	0.603TrpGln: 0.603 ± 0.024	0.981TrpArg: 0.981 ± 0.031	0.755TrpSer: 0.755 ± 0.029	0.747TrpThr: 0.747 ± 0.027	0.943TrpVal: 0.943 ± 0.031	0.21TrpTrp: 0.21 ± 0.016	0.259TrpTyr: 0.259 ± 0.015	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.589TyrAla: 2.589 ± 0.055	0.24TyrCys: 0.24 ± 0.013	1.673TyrAsp: 1.673 ± 0.044	1.239TyrGlu: 1.239 ± 0.035	0.963TyrPhe: 0.963 ± 0.03	2.121TyrGly: 2.121 ± 0.048	0.545TyrHis: 0.545 ± 0.022	1.097TyrIle: 1.097 ± 0.029	0.704TyrLys: 0.704 ± 0.028	2.35TyrLeu: 2.35 ± 0.052	0.535TyrMet: 0.535 ± 0.022	0.677TyrAsn: 0.677 ± 0.027	1.091TyrPro: 1.091 ± 0.033	0.742TyrGln: 0.742 ± 0.027	1.403TyrArg: 1.403 ± 0.035	1.208TyrSer: 1.208 ± 0.035	1.184TyrThr: 1.184 ± 0.031	1.559TyrVal: 1.559 ± 0.037	0.353TyrTrp: 0.353 ± 0.017	0.604TyrTyr: 0.604 ± 0.027	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3434 proteins (1079271 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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