Amino acid dipepetide frequency for Wenzhou tapeworm virus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.092AlaAla: 6.092 ± 2.339
0.29AlaCys: 0.29 ± 0.172
5.512AlaAsp: 5.512 ± 0.994
4.352AlaGlu: 4.352 ± 1.202
2.611AlaPhe: 2.611 ± 0.364
2.611AlaGly: 2.611 ± 0.755
1.451AlaHis: 1.451 ± 0.832
2.031AlaIle: 2.031 ± 1.01
3.771AlaLys: 3.771 ± 0.805
8.703AlaLeu: 8.703 ± 1.433
1.16AlaMet: 1.16 ± 1.19
1.741AlaAsn: 1.741 ± 0.782
2.321AlaPro: 2.321 ± 1.578
2.321AlaGln: 2.321 ± 0.98
4.062AlaArg: 4.062 ± 0.671
6.672AlaSer: 6.672 ± 1.276
2.611AlaThr: 2.611 ± 1.112
5.222AlaVal: 5.222 ± 0.776
1.451AlaTrp: 1.451 ± 0.803
3.771AlaTyr: 3.771 ± 0.659
0.0AlaXaa: 0.0 ± 0.0
Cys
1.16CysAla: 1.16 ± 0.69
0.29CysCys: 0.29 ± 0.401
1.16CysAsp: 1.16 ± 0.36
0.29CysGlu: 0.29 ± 0.172
0.29CysPhe: 0.29 ± 0.172
0.87CysGly: 0.87 ± 1.152
0.0CysHis: 0.0 ± 0.0
1.16CysIle: 1.16 ± 1.038
0.29CysLys: 0.29 ± 0.325
3.771CysLeu: 3.771 ± 1.702
0.29CysMet: 0.29 ± 0.962
0.58CysAsn: 0.58 ± 0.232
1.16CysPro: 1.16 ± 0.465
1.451CysGln: 1.451 ± 0.45
1.741CysArg: 1.741 ± 0.758
0.87CysSer: 0.87 ± 0.379
1.451CysThr: 1.451 ± 0.941
1.451CysVal: 1.451 ± 0.286
0.0CysTrp: 0.0 ± 0.0
1.741CysTyr: 1.741 ± 0.666
0.0CysXaa: 0.0 ± 0.0
Asp
3.481AspAla: 3.481 ± 1.455
0.58AspCys: 0.58 ± 0.232
2.321AspAsp: 2.321 ± 0.66
1.451AspGlu: 1.451 ± 0.849
2.031AspPhe: 2.031 ± 0.508
2.901AspGly: 2.901 ± 0.903
1.451AspHis: 1.451 ± 0.601
3.191AspIle: 3.191 ± 0.644
2.611AspLys: 2.611 ± 0.641
6.092AspLeu: 6.092 ± 1.487
1.451AspMet: 1.451 ± 1.089
1.451AspAsn: 1.451 ± 0.849
4.642AspPro: 4.642 ± 1.23
3.191AspGln: 3.191 ± 1.104
2.611AspArg: 2.611 ± 0.981
4.062AspSer: 4.062 ± 0.951
1.741AspThr: 1.741 ± 0.748
3.481AspVal: 3.481 ± 1.088
0.58AspTrp: 0.58 ± 0.345
2.611AspTyr: 2.611 ± 0.638
0.0AspXaa: 0.0 ± 0.0
Glu
4.352GluAla: 4.352 ± 1.238
0.58GluCys: 0.58 ± 0.232
2.901GluAsp: 2.901 ± 1.004
3.191GluGlu: 3.191 ± 0.774
2.031GluPhe: 2.031 ± 1.082
3.191GluGly: 3.191 ± 1.189
1.16GluHis: 1.16 ± 1.05
4.062GluIle: 4.062 ± 0.842
3.191GluLys: 3.191 ± 1.073
4.642GluLeu: 4.642 ± 1.84
1.16GluMet: 1.16 ± 0.36
2.031GluAsn: 2.031 ± 0.508
3.191GluPro: 3.191 ± 0.947
1.741GluGln: 1.741 ± 0.666
2.901GluArg: 2.901 ± 1.485
5.222GluSer: 5.222 ± 0.776
2.611GluThr: 2.611 ± 0.899
4.932GluVal: 4.932 ± 1.433
1.451GluTrp: 1.451 ± 0.506
1.741GluTyr: 1.741 ± 0.499
0.0GluXaa: 0.0 ± 0.0
Phe
1.741PheAla: 1.741 ± 0.781
1.451PheCys: 1.451 ± 1.018
2.031PheAsp: 2.031 ± 0.508
3.481PheGlu: 3.481 ± 0.864
2.901PhePhe: 2.901 ± 1.025
1.451PheGly: 1.451 ± 0.454
1.16PheHis: 1.16 ± 0.288
3.481PheIle: 3.481 ± 0.738
2.031PheLys: 2.031 ± 0.907
4.932PheLeu: 4.932 ± 1.156
0.58PheMet: 0.58 ± 0.499
0.58PheAsn: 0.58 ± 0.354
1.16PhePro: 1.16 ± 0.471
1.451PheGln: 1.451 ± 0.601
2.321PheArg: 2.321 ± 0.627
2.901PheSer: 2.901 ± 0.839
1.741PheThr: 1.741 ± 1.796
1.741PheVal: 1.741 ± 0.499
0.0PheTrp: 0.0 ± 0.0
0.58PheTyr: 0.58 ± 0.232
0.0PheXaa: 0.0 ± 0.0
Gly
2.611GlyAla: 2.611 ± 1.109
1.451GlyCys: 1.451 ± 0.83
2.901GlyAsp: 2.901 ± 1.583
2.611GlyGlu: 2.611 ± 1.166
1.741GlyPhe: 1.741 ± 0.666
3.481GlyGly: 3.481 ± 1.825
3.481GlyHis: 3.481 ± 2.488
2.031GlyIle: 2.031 ± 0.659
1.451GlyLys: 1.451 ± 0.485
6.092GlyLeu: 6.092 ± 1.892
1.16GlyMet: 1.16 ± 0.745
1.16GlyAsn: 1.16 ± 0.36
2.611GlyPro: 2.611 ± 0.898
2.031GlyGln: 2.031 ± 0.508
4.352GlyArg: 4.352 ± 1.11
4.062GlySer: 4.062 ± 1.919
2.321GlyThr: 2.321 ± 1.849
4.642GlyVal: 4.642 ± 1.031
0.87GlyTrp: 0.87 ± 0.517
2.031GlyTyr: 2.031 ± 0.361
0.0GlyXaa: 0.0 ± 0.0
His
0.87HisAla: 0.87 ± 0.923
1.16HisCys: 1.16 ± 0.857
0.87HisAsp: 0.87 ± 0.379
0.87HisGlu: 0.87 ± 0.76
1.741HisPhe: 1.741 ± 0.923
2.031HisGly: 2.031 ± 0.462
0.58HisHis: 0.58 ± 0.345
1.16HisIle: 1.16 ± 0.69
1.451HisLys: 1.451 ± 1.808
4.352HisLeu: 4.352 ± 1.925
1.16HisMet: 1.16 ± 0.304
0.58HisAsn: 0.58 ± 0.232
2.321HisPro: 2.321 ± 0.71
0.58HisGln: 0.58 ± 0.348
2.901HisArg: 2.901 ± 0.549
1.451HisSer: 1.451 ± 0.832
1.16HisThr: 1.16 ± 0.465
1.16HisVal: 1.16 ± 0.69
0.87HisTrp: 0.87 ± 0.377
2.031HisTyr: 2.031 ± 0.716
0.0HisXaa: 0.0 ± 0.0
Ile
3.191IleAla: 3.191 ± 0.613
1.16IleCys: 1.16 ± 0.915
1.741IleAsp: 1.741 ± 0.596
4.932IleGlu: 4.932 ± 1.194
1.741IlePhe: 1.741 ± 0.666
2.031IleGly: 2.031 ± 0.904
0.87IleHis: 0.87 ± 0.249
2.611IleIle: 2.611 ± 0.364
3.481IleLys: 3.481 ± 1.553
6.092IleLeu: 6.092 ± 1.542
1.741IleMet: 1.741 ± 0.684
2.901IleAsn: 2.901 ± 1.207
4.062IlePro: 4.062 ± 1.016
1.741IleGln: 1.741 ± 0.773
5.222IleArg: 5.222 ± 1.178
5.512IleSer: 5.512 ± 1.382
4.352IleThr: 4.352 ± 0.695
4.352IleVal: 4.352 ± 2.591
0.29IleTrp: 0.29 ± 0.172
1.16IleTyr: 1.16 ± 0.915
0.0IleXaa: 0.0 ± 0.0
Lys
4.642LysAla: 4.642 ± 1.843
1.451LysCys: 1.451 ± 0.45
2.901LysAsp: 2.901 ± 0.623
1.741LysGlu: 1.741 ± 0.748
1.451LysPhe: 1.451 ± 1.953
2.321LysGly: 2.321 ± 0.998
1.16LysHis: 1.16 ± 1.829
2.031LysIle: 2.031 ± 0.83
1.16LysLys: 1.16 ± 1.829
3.771LysLeu: 3.771 ± 1.704
0.87LysMet: 0.87 ± 0.379
1.16LysAsn: 1.16 ± 0.915
2.031LysPro: 2.031 ± 0.565
1.16LysGln: 1.16 ± 1.829
2.611LysArg: 2.611 ± 1.332
1.451LysSer: 1.451 ± 0.601
2.321LysThr: 2.321 ± 1.486
2.611LysVal: 2.611 ± 0.827
1.16LysTrp: 1.16 ± 0.69
1.451LysTyr: 1.451 ± 0.805
0.0LysXaa: 0.0 ± 0.0
Leu
6.963LeuAla: 6.963 ± 0.594
2.321LeuCys: 2.321 ± 0.935
5.802LeuAsp: 5.802 ± 1.328
4.932LeuGlu: 4.932 ± 1.185
2.611LeuPhe: 2.611 ± 0.82
5.802LeuGly: 5.802 ± 2.207
2.611LeuHis: 2.611 ± 0.82
6.092LeuIle: 6.092 ± 1.042
2.611LeuLys: 2.611 ± 0.82
10.734LeuLeu: 10.734 ± 2.175
2.611LeuMet: 2.611 ± 0.513
2.321LeuAsn: 2.321 ± 1.03
7.833LeuPro: 7.833 ± 2.456
4.642LeuGln: 4.642 ± 1.338
6.382LeuArg: 6.382 ± 1.022
9.574LeuSer: 9.574 ± 2.181
5.222LeuThr: 5.222 ± 1.461
5.222LeuVal: 5.222 ± 2.06
2.321LeuTrp: 2.321 ± 0.721
6.092LeuTyr: 6.092 ± 2.115
0.0LeuXaa: 0.0 ± 0.0
Met
2.321MetAla: 2.321 ± 1.066
0.58MetCys: 0.58 ± 0.232
1.741MetAsp: 1.741 ± 0.914
1.16MetGlu: 1.16 ± 0.288
0.29MetPhe: 0.29 ± 0.172
1.451MetGly: 1.451 ± 0.862
0.87MetHis: 0.87 ± 0.538
2.031MetIle: 2.031 ± 0.716
1.16MetLys: 1.16 ± 0.69
1.451MetLeu: 1.451 ± 0.803
0.29MetMet: 0.29 ± 0.401
0.29MetAsn: 0.29 ± 0.401
1.16MetPro: 1.16 ± 0.36
0.87MetGln: 0.87 ± 0.731
1.741MetArg: 1.741 ± 0.499
2.321MetSer: 2.321 ± 0.508
3.771MetThr: 3.771 ± 1.205
1.16MetVal: 1.16 ± 1.233
0.0MetTrp: 0.0 ± 0.0
0.87MetTyr: 0.87 ± 0.377
0.0MetXaa: 0.0 ± 0.0
Asn
2.901AsnAla: 2.901 ± 0.709
0.58AsnCys: 0.58 ± 0.345
1.451AsnAsp: 1.451 ± 0.601
0.87AsnGlu: 0.87 ± 0.76
2.031AsnPhe: 2.031 ± 0.361
0.58AsnGly: 0.58 ± 0.232
0.58AsnHis: 0.58 ± 0.348
2.611AsnIle: 2.611 ± 1.179
1.741AsnLys: 1.741 ± 0.621
3.481AsnLeu: 3.481 ± 0.953
0.87AsnMet: 0.87 ± 0.517
1.451AsnAsn: 1.451 ± 0.83
3.191AsnPro: 3.191 ± 0.911
2.031AsnGln: 2.031 ± 0.668
0.87AsnArg: 0.87 ± 0.731
1.16AsnSer: 1.16 ± 0.471
2.031AsnThr: 2.031 ± 0.587
2.901AsnVal: 2.901 ± 1.152
0.29AsnTrp: 0.29 ± 0.172
0.87AsnTyr: 0.87 ± 0.249
0.0AsnXaa: 0.0 ± 0.0
Pro
4.062ProAla: 4.062 ± 1.662
0.58ProCys: 0.58 ± 0.649
2.321ProAsp: 2.321 ± 0.715
6.382ProGlu: 6.382 ± 0.271
2.321ProPhe: 2.321 ± 0.576
3.481ProGly: 3.481 ± 0.924
1.451ProHis: 1.451 ± 0.506
2.321ProIle: 2.321 ± 0.627
1.451ProLys: 1.451 ± 0.485
4.642ProLeu: 4.642 ± 1.404
1.16ProMet: 1.16 ± 0.288
2.611ProAsn: 2.611 ± 0.548
2.611ProPro: 2.611 ± 1.092
2.901ProGln: 2.901 ± 0.821
2.611ProArg: 2.611 ± 0.708
3.481ProSer: 3.481 ± 1.156
5.222ProThr: 5.222 ± 2.021
3.481ProVal: 3.481 ± 1.12
1.451ProTrp: 1.451 ± 0.862
3.481ProTyr: 3.481 ± 0.953
0.0ProXaa: 0.0 ± 0.0
Gln
2.901GlnAla: 2.901 ± 0.964
0.87GlnCys: 0.87 ± 1.054
2.031GlnAsp: 2.031 ± 1.126
3.481GlnGlu: 3.481 ± 1.908
0.29GlnPhe: 0.29 ± 0.396
2.611GlnGly: 2.611 ± 0.628
1.741GlnHis: 1.741 ± 0.773
2.031GlnIle: 2.031 ± 0.926
1.16GlnLys: 1.16 ± 0.471
1.741GlnLeu: 1.741 ± 1.075
0.0GlnMet: 0.0 ± 0.0
1.451GlnAsn: 1.451 ± 1.047
1.741GlnPro: 1.741 ± 1.035
1.451GlnGln: 1.451 ± 0.454
3.771GlnArg: 3.771 ± 1.499
1.741GlnSer: 1.741 ± 0.379
4.062GlnThr: 4.062 ± 0.813
3.771GlnVal: 3.771 ± 0.839
0.58GlnTrp: 0.58 ± 0.232
0.87GlnTyr: 0.87 ± 0.377
0.0GlnXaa: 0.0 ± 0.0
Arg
3.481ArgAla: 3.481 ± 0.608
1.451ArgCys: 1.451 ± 0.507
3.771ArgAsp: 3.771 ± 0.729
3.771ArgGlu: 3.771 ± 1.496
4.062ArgPhe: 4.062 ± 1.948
4.642ArgGly: 4.642 ± 1.362
1.741ArgHis: 1.741 ± 0.77
4.932ArgIle: 4.932 ± 0.964
2.031ArgLys: 2.031 ± 0.375
6.963ArgLeu: 6.963 ± 1.428
1.16ArgMet: 1.16 ± 0.697
2.321ArgAsn: 2.321 ± 0.408
3.191ArgPro: 3.191 ± 1.109
2.031ArgGln: 2.031 ± 0.375
2.901ArgArg: 2.901 ± 0.647
4.932ArgSer: 4.932 ± 1.01
3.481ArgThr: 3.481 ± 0.714
4.932ArgVal: 4.932 ± 0.975
2.031ArgTrp: 2.031 ± 0.907
1.16ArgTyr: 1.16 ± 0.662
0.0ArgXaa: 0.0 ± 0.0
Ser
4.062SerAla: 4.062 ± 1.135
1.16SerCys: 1.16 ± 0.36
3.191SerAsp: 3.191 ± 0.644
5.222SerGlu: 5.222 ± 0.728
4.062SerPhe: 4.062 ± 1.016
4.352SerGly: 4.352 ± 2.057
2.611SerHis: 2.611 ± 0.364
6.092SerIle: 6.092 ± 1.749
2.901SerLys: 2.901 ± 0.642
8.703SerLeu: 8.703 ± 2.01
2.901SerMet: 2.901 ± 0.549
3.481SerAsn: 3.481 ± 1.156
3.191SerPro: 3.191 ± 0.933
0.87SerGln: 0.87 ± 0.42
5.222SerArg: 5.222 ± 1.202
7.543SerSer: 7.543 ± 1.837
5.222SerThr: 5.222 ± 1.139
5.512SerVal: 5.512 ± 2.703
0.29SerTrp: 0.29 ± 0.172
1.741SerTyr: 1.741 ± 0.666
0.0SerXaa: 0.0 ± 0.0
Thr
4.932ThrAla: 4.932 ± 0.751
1.451ThrCys: 1.451 ± 0.45
1.741ThrAsp: 1.741 ± 0.479
2.611ThrGlu: 2.611 ± 0.621
2.901ThrPhe: 2.901 ± 0.737
3.771ThrGly: 3.771 ± 3.478
1.16ThrHis: 1.16 ± 0.69
4.642ThrIle: 4.642 ± 2.04
1.741ThrLys: 1.741 ± 0.379
4.932ThrLeu: 4.932 ± 1.013
1.451ThrMet: 1.451 ± 0.286
1.741ThrAsn: 1.741 ± 0.499
4.062ThrPro: 4.062 ± 1.239
2.321ThrGln: 2.321 ± 0.93
4.352ThrArg: 4.352 ± 1.494
5.802ThrSer: 5.802 ± 1.13
3.771ThrThr: 3.771 ± 2.818
3.481ThrVal: 3.481 ± 1.806
1.16ThrTrp: 1.16 ± 0.288
2.611ThrTyr: 2.611 ± 0.899
0.0ThrXaa: 0.0 ± 0.0
Val
5.512ValAla: 5.512 ± 1.954
1.741ValCys: 1.741 ± 0.835
4.642ValAsp: 4.642 ± 1.345
2.611ValGlu: 2.611 ± 0.364
0.87ValPhe: 0.87 ± 0.517
3.191ValGly: 3.191 ± 1.482
3.191ValHis: 3.191 ± 2.057
2.901ValIle: 2.901 ± 0.572
2.901ValLys: 2.901 ± 0.722
6.092ValLeu: 6.092 ± 1.629
2.321ValMet: 2.321 ± 0.817
2.611ValAsn: 2.611 ± 0.535
4.352ValPro: 4.352 ± 1.065
2.611ValGln: 2.611 ± 1.849
5.222ValArg: 5.222 ± 0.781
6.963ValSer: 6.963 ± 0.763
3.481ValThr: 3.481 ± 1.828
5.512ValVal: 5.512 ± 2.553
0.0ValTrp: 0.0 ± 0.0
2.611ValTyr: 2.611 ± 1.137
0.0ValXaa: 0.0 ± 0.0
Trp
0.87TrpAla: 0.87 ± 0.898
0.29TrpCys: 0.29 ± 0.172
1.741TrpAsp: 1.741 ± 0.748
0.29TrpGlu: 0.29 ± 0.401
0.0TrpPhe: 0.0 ± 0.0
0.58TrpGly: 0.58 ± 0.232
0.29TrpHis: 0.29 ± 0.172
1.741TrpIle: 1.741 ± 0.748
0.58TrpLys: 0.58 ± 0.345
1.16TrpLeu: 1.16 ± 0.471
0.58TrpMet: 0.58 ± 0.345
0.29TrpAsn: 0.29 ± 0.172
1.16TrpPro: 1.16 ± 0.69
0.58TrpGln: 0.58 ± 0.354
0.29TrpArg: 0.29 ± 0.401
0.87TrpSer: 0.87 ± 0.517
0.87TrpThr: 0.87 ± 0.391
2.321TrpVal: 2.321 ± 0.408
0.0TrpTrp: 0.0 ± 0.0
0.58TrpTyr: 0.58 ± 0.232
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.611TyrAla: 2.611 ± 0.559
0.58TyrCys: 0.58 ± 0.348
1.16TyrAsp: 1.16 ± 0.36
2.031TyrGlu: 2.031 ± 0.672
1.741TyrPhe: 1.741 ± 0.374
1.741TyrGly: 1.741 ± 0.748
2.031TyrHis: 2.031 ± 1.014
2.031TyrIle: 2.031 ± 0.361
1.741TyrLys: 1.741 ± 1.237
4.352TyrLeu: 4.352 ± 1.185
2.321TyrMet: 2.321 ± 0.66
1.741TyrAsn: 1.741 ± 0.578
2.031TyrPro: 2.031 ± 1.207
2.321TyrGln: 2.321 ± 0.835
2.901TyrArg: 2.901 ± 0.724
1.741TyrSer: 1.741 ± 0.499
3.191TyrThr: 3.191 ± 0.613
1.451TyrVal: 1.451 ± 0.286
0.29TyrTrp: 0.29 ± 0.172
0.87TyrTyr: 0.87 ± 0.377
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 5 proteins (3448 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski