Amino acid dipepetide frequency for Tapara virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.797AlaAla: 3.797 ± 3.037
1.266AlaCys: 1.266 ± 0.622
1.519AlaAsp: 1.519 ± 0.784
3.544AlaGlu: 3.544 ± 0.957
2.785AlaPhe: 2.785 ± 1.441
3.291AlaGly: 3.291 ± 0.733
1.266AlaHis: 1.266 ± 0.592
4.051AlaIle: 4.051 ± 1.374
1.266AlaLys: 1.266 ± 0.894
5.316AlaLeu: 5.316 ± 0.822
1.266AlaMet: 1.266 ± 0.341
0.759AlaAsn: 0.759 ± 0.987
1.772AlaPro: 1.772 ± 0.463
1.266AlaGln: 1.266 ± 0.333
2.278AlaArg: 2.278 ± 0.598
6.076AlaSer: 6.076 ± 0.704
3.797AlaThr: 3.797 ± 0.32
2.785AlaVal: 2.785 ± 0.865
0.0AlaTrp: 0.0 ± 0.0
1.519AlaTyr: 1.519 ± 0.617
0.0AlaXaa: 0.0 ± 0.0
Cys
0.506CysAla: 0.506 ± 0.449
0.759CysCys: 0.759 ± 0.219
0.759CysAsp: 0.759 ± 0.219
1.266CysGlu: 1.266 ± 0.735
1.772CysPhe: 1.772 ± 0.848
1.519CysGly: 1.519 ± 0.792
1.266CysHis: 1.266 ± 0.333
1.266CysIle: 1.266 ± 0.735
1.519CysLys: 1.519 ± 0.645
2.278CysLeu: 2.278 ± 1.374
0.506CysMet: 0.506 ± 0.143
0.759CysAsn: 0.759 ± 0.323
0.506CysPro: 0.506 ± 0.143
1.266CysGln: 1.266 ± 0.592
0.759CysArg: 0.759 ± 0.323
3.038CysSer: 3.038 ± 1.309
2.025CysThr: 2.025 ± 0.57
1.519CysVal: 1.519 ± 1.436
0.0CysTrp: 0.0 ± 0.0
1.266CysTyr: 1.266 ± 0.735
0.0CysXaa: 0.0 ± 0.0
Asp
2.532AspAla: 2.532 ± 1.131
1.772AspCys: 1.772 ± 1.112
4.304AspAsp: 4.304 ± 0.69
5.063AspGlu: 5.063 ± 0.914
2.532AspPhe: 2.532 ± 1.353
2.785AspGly: 2.785 ± 0.814
0.506AspHis: 0.506 ± 0.143
3.797AspIle: 3.797 ± 1.194
4.557AspLys: 4.557 ± 0.867
4.051AspLeu: 4.051 ± 0.813
3.544AspMet: 3.544 ± 0.627
1.772AspAsn: 1.772 ± 0.571
2.785AspPro: 2.785 ± 1.125
0.759AspGln: 0.759 ± 0.441
2.278AspArg: 2.278 ± 0.663
4.051AspSer: 4.051 ± 0.677
2.025AspThr: 2.025 ± 0.835
3.544AspVal: 3.544 ± 0.63
1.519AspTrp: 1.519 ± 0.271
2.785AspTyr: 2.785 ± 0.311
0.0AspXaa: 0.0 ± 0.0
Glu
4.304GluAla: 4.304 ± 0.62
2.532GluCys: 2.532 ± 0.904
4.81GluAsp: 4.81 ± 1.581
8.861GluGlu: 8.861 ± 1.992
3.797GluPhe: 3.797 ± 0.617
5.316GluGly: 5.316 ± 0.958
1.013GluHis: 1.013 ± 0.285
3.797GluIle: 3.797 ± 0.378
5.823GluLys: 5.823 ± 1.237
7.089GluLeu: 7.089 ± 1.156
3.544GluMet: 3.544 ± 0.592
2.532GluAsn: 2.532 ± 0.899
1.266GluPro: 1.266 ± 0.614
2.278GluGln: 2.278 ± 0.866
4.051GluArg: 4.051 ± 0.677
7.089GluSer: 7.089 ± 1.53
3.291GluThr: 3.291 ± 0.777
4.051GluVal: 4.051 ± 0.523
0.253GluTrp: 0.253 ± 0.162
0.759GluTyr: 0.759 ± 0.219
0.0GluXaa: 0.0 ± 0.0
Phe
2.532PheAla: 2.532 ± 0.708
1.013PheCys: 1.013 ± 0.527
2.785PheAsp: 2.785 ± 1.012
2.785PheGlu: 2.785 ± 0.736
2.532PhePhe: 2.532 ± 0.665
1.519PheGly: 1.519 ± 0.438
1.013PheHis: 1.013 ± 0.285
3.291PheIle: 3.291 ± 0.588
3.544PheLys: 3.544 ± 0.957
3.544PheLeu: 3.544 ± 0.979
3.038PheMet: 3.038 ± 0.659
1.519PheAsn: 1.519 ± 0.265
1.266PhePro: 1.266 ± 0.51
0.759PheGln: 0.759 ± 0.404
3.291PheArg: 3.291 ± 1.546
6.582PheSer: 6.582 ± 0.837
3.544PheThr: 3.544 ± 0.716
3.038PheVal: 3.038 ± 0.391
0.506PheTrp: 0.506 ± 0.323
0.759PheTyr: 0.759 ± 0.441
0.0PheXaa: 0.0 ± 0.0
Gly
3.544GlyAla: 3.544 ± 0.684
1.013GlyCys: 1.013 ± 0.527
3.038GlyAsp: 3.038 ± 0.669
3.797GlyGlu: 3.797 ± 0.508
4.051GlyPhe: 4.051 ± 0.64
4.304GlyGly: 4.304 ± 1.197
2.532GlyHis: 2.532 ± 0.606
3.797GlyIle: 3.797 ± 0.562
4.81GlyLys: 4.81 ± 0.817
3.291GlyLeu: 3.291 ± 0.443
1.266GlyMet: 1.266 ± 0.32
1.772GlyAsn: 1.772 ± 1.073
2.532GlyPro: 2.532 ± 0.665
0.759GlyGln: 0.759 ± 1.022
2.532GlyArg: 2.532 ± 0.972
5.57GlySer: 5.57 ± 0.448
3.291GlyThr: 3.291 ± 0.869
2.532GlyVal: 2.532 ± 0.663
0.759GlyTrp: 0.759 ± 0.635
1.519GlyTyr: 1.519 ± 0.66
0.0GlyXaa: 0.0 ± 0.0
His
1.519HisAla: 1.519 ± 0.396
1.013HisCys: 1.013 ± 0.847
1.266HisAsp: 1.266 ± 0.332
0.759HisGlu: 0.759 ± 0.457
1.013HisPhe: 1.013 ± 0.517
2.278HisGly: 2.278 ± 0.598
0.506HisHis: 0.506 ± 0.323
2.532HisIle: 2.532 ± 1.02
2.025HisLys: 2.025 ± 1.054
3.038HisLeu: 3.038 ± 0.653
0.0HisMet: 0.0 ± 0.0
0.759HisAsn: 0.759 ± 0.219
2.025HisPro: 2.025 ± 0.48
0.506HisGln: 0.506 ± 0.323
1.013HisArg: 1.013 ± 0.34
1.772HisSer: 1.772 ± 0.947
0.759HisThr: 0.759 ± 0.219
1.013HisVal: 1.013 ± 0.358
0.0HisTrp: 0.0 ± 0.0
1.772HisTyr: 1.772 ± 0.463
0.0HisXaa: 0.0 ± 0.0
Ile
2.278IleAla: 2.278 ± 0.663
1.519IleCys: 1.519 ± 0.438
4.051IleAsp: 4.051 ± 0.757
5.063IleGlu: 5.063 ± 1.159
2.025IlePhe: 2.025 ± 0.978
3.544IleGly: 3.544 ± 0.998
1.772IleHis: 1.772 ± 0.347
4.304IleIle: 4.304 ± 1.128
4.557IleLys: 4.557 ± 1.56
6.329IleLeu: 6.329 ± 1.658
1.266IleMet: 1.266 ± 0.333
2.532IleAsn: 2.532 ± 1.131
2.025IlePro: 2.025 ± 0.48
2.532IleGln: 2.532 ± 0.972
3.291IleArg: 3.291 ± 1.005
7.848IleSer: 7.848 ± 1.043
5.063IleThr: 5.063 ± 1.59
5.57IleVal: 5.57 ± 1.523
0.759IleTrp: 0.759 ± 0.219
3.291IleTyr: 3.291 ± 0.803
0.0IleXaa: 0.0 ± 0.0
Lys
2.532LysAla: 2.532 ± 0.788
1.266LysCys: 1.266 ± 0.735
4.304LysAsp: 4.304 ± 1.43
6.076LysGlu: 6.076 ± 0.796
3.797LysPhe: 3.797 ± 0.998
3.291LysGly: 3.291 ± 0.838
1.266LysHis: 1.266 ± 0.333
7.848LysIle: 7.848 ± 1.998
4.557LysLys: 4.557 ± 0.565
5.57LysLeu: 5.57 ± 0.753
3.544LysMet: 3.544 ± 1.679
4.051LysAsn: 4.051 ± 0.701
1.519LysPro: 1.519 ± 0.438
2.278LysGln: 2.278 ± 0.658
3.544LysArg: 3.544 ± 0.925
5.823LysSer: 5.823 ± 0.566
3.291LysThr: 3.291 ± 0.869
4.557LysVal: 4.557 ± 2.23
1.266LysTrp: 1.266 ± 0.332
1.772LysTyr: 1.772 ± 0.287
0.0LysXaa: 0.0 ± 0.0
Leu
4.557LeuAla: 4.557 ± 1.0
1.266LeuCys: 1.266 ± 0.51
5.063LeuAsp: 5.063 ± 1.453
5.57LeuGlu: 5.57 ± 1.855
3.544LeuPhe: 3.544 ± 0.957
4.051LeuGly: 4.051 ± 0.653
1.519LeuHis: 1.519 ± 0.428
6.329LeuIle: 6.329 ± 1.86
6.329LeuLys: 6.329 ± 1.033
6.076LeuLeu: 6.076 ± 1.111
2.025LeuMet: 2.025 ± 0.637
4.304LeuAsn: 4.304 ± 0.836
3.038LeuPro: 3.038 ± 0.814
3.291LeuGln: 3.291 ± 0.719
6.835LeuArg: 6.835 ± 1.082
7.089LeuSer: 7.089 ± 0.911
4.304LeuThr: 4.304 ± 1.033
4.81LeuVal: 4.81 ± 0.726
0.0LeuTrp: 0.0 ± 0.0
2.278LeuTyr: 2.278 ± 1.201
0.0LeuXaa: 0.0 ± 0.0
Met
1.266MetAla: 1.266 ± 0.356
0.506MetCys: 0.506 ± 0.423
2.532MetAsp: 2.532 ± 1.189
2.278MetGlu: 2.278 ± 1.06
1.519MetPhe: 1.519 ± 0.667
1.772MetGly: 1.772 ± 0.463
1.266MetHis: 1.266 ± 0.614
2.785MetIle: 2.785 ± 0.771
2.278MetLys: 2.278 ± 0.282
2.278MetLeu: 2.278 ± 0.507
1.519MetMet: 1.519 ± 0.735
1.266MetAsn: 1.266 ± 0.452
0.759MetPro: 0.759 ± 0.441
1.772MetGln: 1.772 ± 0.463
1.772MetArg: 1.772 ± 0.333
3.038MetSer: 3.038 ± 1.316
1.519MetThr: 1.519 ± 0.945
1.519MetVal: 1.519 ± 0.667
0.0MetTrp: 0.0 ± 0.0
1.013MetTyr: 1.013 ± 0.897
0.0MetXaa: 0.0 ± 0.0
Asn
2.278AsnAla: 2.278 ± 1.421
0.506AsnCys: 0.506 ± 0.423
3.038AsnAsp: 3.038 ± 0.791
4.557AsnGlu: 4.557 ± 1.566
2.278AsnPhe: 2.278 ± 0.866
1.266AsnGly: 1.266 ± 0.51
0.506AsnHis: 0.506 ± 0.323
1.772AsnIle: 1.772 ± 0.545
2.532AsnLys: 2.532 ± 0.378
3.038AsnLeu: 3.038 ± 0.911
0.759AsnMet: 0.759 ± 0.219
1.772AsnAsn: 1.772 ± 0.646
2.785AsnPro: 2.785 ± 0.935
1.266AsnGln: 1.266 ± 0.622
2.532AsnArg: 2.532 ± 0.899
3.544AsnSer: 3.544 ± 1.537
0.253AsnThr: 0.253 ± 0.162
1.772AsnVal: 1.772 ± 0.978
0.253AsnTrp: 0.253 ± 0.5
2.025AsnTyr: 2.025 ± 0.81
0.0AsnXaa: 0.0 ± 0.0
Pro
1.266ProAla: 1.266 ± 0.785
0.0ProCys: 0.0 ± 0.0
2.025ProAsp: 2.025 ± 0.767
4.304ProGlu: 4.304 ± 1.843
1.772ProPhe: 1.772 ± 0.463
1.772ProGly: 1.772 ± 0.463
0.759ProHis: 0.759 ± 0.457
1.266ProIle: 1.266 ± 0.785
2.532ProLys: 2.532 ± 0.787
4.304ProLeu: 4.304 ± 1.323
1.266ProMet: 1.266 ± 0.829
1.772ProAsn: 1.772 ± 0.743
0.253ProPro: 0.253 ± 0.162
1.013ProGln: 1.013 ± 0.485
1.519ProArg: 1.519 ± 0.452
3.544ProSer: 3.544 ± 0.548
1.772ProThr: 1.772 ± 1.141
2.278ProVal: 2.278 ± 0.949
1.013ProTrp: 1.013 ± 0.646
1.266ProTyr: 1.266 ± 0.333
0.0ProXaa: 0.0 ± 0.0
Gln
1.772GlnAla: 1.772 ± 0.969
1.266GlnCys: 1.266 ± 0.622
1.013GlnAsp: 1.013 ± 0.34
2.785GlnGlu: 2.785 ± 0.627
1.772GlnPhe: 1.772 ± 0.825
1.519GlnGly: 1.519 ± 0.735
1.266GlnHis: 1.266 ± 0.51
2.278GlnIle: 2.278 ± 0.507
2.278GlnLys: 2.278 ± 0.866
0.759GlnLeu: 0.759 ± 0.219
1.013GlnMet: 1.013 ± 0.46
1.266GlnAsn: 1.266 ± 1.43
1.519GlnPro: 1.519 ± 0.617
1.013GlnGln: 1.013 ± 0.344
0.759GlnArg: 0.759 ± 0.808
2.025GlnSer: 2.025 ± 0.68
1.266GlnThr: 1.266 ± 0.51
1.266GlnVal: 1.266 ± 0.51
0.253GlnTrp: 0.253 ± 0.212
0.759GlnTyr: 0.759 ± 0.441
0.0GlnXaa: 0.0 ± 0.0
Arg
3.544ArgAla: 3.544 ± 0.922
1.519ArgCys: 1.519 ± 0.645
3.291ArgAsp: 3.291 ± 0.706
3.544ArgGlu: 3.544 ± 0.977
1.519ArgPhe: 1.519 ± 0.265
3.291ArgGly: 3.291 ± 0.733
1.013ArgHis: 1.013 ± 0.285
5.316ArgIle: 5.316 ± 0.617
2.025ArgLys: 2.025 ± 0.835
3.544ArgLeu: 3.544 ± 0.642
0.506ArgMet: 0.506 ± 0.323
2.532ArgAsn: 2.532 ± 0.904
2.532ArgPro: 2.532 ± 0.889
1.772ArgGln: 1.772 ± 0.505
2.785ArgArg: 2.785 ± 0.311
4.557ArgSer: 4.557 ± 2.0
3.797ArgThr: 3.797 ± 0.726
4.81ArgVal: 4.81 ± 0.918
1.519ArgTrp: 1.519 ± 0.755
1.013ArgTyr: 1.013 ± 0.285
0.0ArgXaa: 0.0 ± 0.0
Ser
4.304SerAla: 4.304 ± 1.358
2.785SerCys: 2.785 ± 1.103
5.063SerAsp: 5.063 ± 0.389
6.076SerGlu: 6.076 ± 0.978
4.304SerPhe: 4.304 ± 0.457
7.595SerGly: 7.595 ± 1.155
3.544SerHis: 3.544 ± 1.394
5.57SerIle: 5.57 ± 0.995
7.848SerLys: 7.848 ± 1.632
8.101SerLeu: 8.101 ± 0.93
1.772SerMet: 1.772 ± 0.825
3.291SerAsn: 3.291 ± 0.876
3.291SerPro: 3.291 ± 0.759
1.013SerGln: 1.013 ± 0.757
6.076SerArg: 6.076 ± 0.478
8.354SerSer: 8.354 ± 0.261
5.063SerThr: 5.063 ± 0.917
5.316SerVal: 5.316 ± 0.787
2.785SerTrp: 2.785 ± 0.814
2.025SerTyr: 2.025 ± 1.311
0.0SerXaa: 0.0 ± 0.0
Thr
1.772ThrAla: 1.772 ± 0.463
1.772ThrCys: 1.772 ± 0.947
2.025ThrAsp: 2.025 ± 0.51
4.557ThrGlu: 4.557 ± 0.506
3.038ThrPhe: 3.038 ± 1.131
3.544ThrGly: 3.544 ± 0.502
0.759ThrHis: 0.759 ± 0.441
3.291ThrIle: 3.291 ± 1.223
4.304ThrLys: 4.304 ± 0.521
6.582ThrLeu: 6.582 ± 0.93
1.013ThrMet: 1.013 ± 0.358
1.772ThrAsn: 1.772 ± 0.463
1.772ThrPro: 1.772 ± 0.347
1.266ThrGln: 1.266 ± 0.333
3.038ThrArg: 3.038 ± 1.876
4.304ThrSer: 4.304 ± 1.125
2.278ThrThr: 2.278 ± 1.261
3.797ThrVal: 3.797 ± 0.807
0.506ThrTrp: 0.506 ± 0.143
1.519ThrTyr: 1.519 ± 0.645
0.0ThrXaa: 0.0 ± 0.0
Val
3.038ValAla: 3.038 ± 0.427
1.266ValCys: 1.266 ± 0.622
3.291ValAsp: 3.291 ± 1.376
3.038ValGlu: 3.038 ± 0.577
2.785ValPhe: 2.785 ± 0.736
2.025ValGly: 2.025 ± 0.985
2.025ValHis: 2.025 ± 0.263
3.544ValIle: 3.544 ± 0.482
6.835ValLys: 6.835 ± 0.897
3.544ValLeu: 3.544 ± 0.474
2.532ValMet: 2.532 ± 0.878
2.278ValAsn: 2.278 ± 1.629
1.266ValPro: 1.266 ± 0.341
2.785ValGln: 2.785 ± 1.286
4.051ValArg: 4.051 ± 0.583
6.835ValSer: 6.835 ± 0.78
3.291ValThr: 3.291 ± 0.857
2.532ValVal: 2.532 ± 0.65
0.253ValTrp: 0.253 ± 0.162
1.772ValTyr: 1.772 ± 0.868
0.0ValXaa: 0.0 ± 0.0
Trp
0.253TrpAla: 0.253 ± 0.212
0.253TrpCys: 0.253 ± 0.162
1.013TrpAsp: 1.013 ± 0.773
0.759TrpGlu: 0.759 ± 0.485
0.506TrpPhe: 0.506 ± 0.323
1.013TrpGly: 1.013 ± 0.34
0.0TrpHis: 0.0 ± 0.0
1.013TrpIle: 1.013 ± 0.485
0.506TrpLys: 0.506 ± 0.451
1.013TrpLeu: 1.013 ± 0.285
1.266TrpMet: 1.266 ± 0.354
0.253TrpAsn: 0.253 ± 0.162
0.506TrpPro: 0.506 ± 0.449
0.0TrpGln: 0.0 ± 0.0
0.506TrpArg: 0.506 ± 0.143
0.506TrpSer: 0.506 ± 0.143
1.013TrpThr: 1.013 ± 0.358
1.266TrpVal: 1.266 ± 0.341
0.253TrpTrp: 0.253 ± 0.162
0.253TrpTyr: 0.253 ± 0.162
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.025TyrAla: 2.025 ± 0.379
1.266TyrCys: 1.266 ± 0.356
1.772TyrAsp: 1.772 ± 0.347
2.025TyrGlu: 2.025 ± 0.734
1.519TyrPhe: 1.519 ± 0.667
1.013TyrGly: 1.013 ± 0.358
1.772TyrHis: 1.772 ± 0.333
1.772TyrIle: 1.772 ± 0.571
2.025TyrLys: 2.025 ± 0.379
2.532TyrLeu: 2.532 ± 1.156
0.759TyrMet: 0.759 ± 0.441
1.772TyrAsn: 1.772 ± 0.545
2.278TyrPro: 2.278 ± 0.653
0.253TyrGln: 0.253 ± 0.511
1.519TyrArg: 1.519 ± 1.348
2.532TyrSer: 2.532 ± 0.65
1.266TyrThr: 1.266 ± 0.678
1.013TyrVal: 1.013 ± 0.358
0.253TyrTrp: 0.253 ± 0.212
0.253TyrTyr: 0.253 ± 0.162
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4 proteins (3951 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski