Amino acid dipepetide frequency for Rhynchosia yellow mosaic virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.44AlaAla: 4.44 ± 0.955
1.11AlaCys: 1.11 ± 0.548
1.11AlaAsp: 1.11 ± 0.815
4.994AlaGlu: 4.994 ± 1.657
2.22AlaPhe: 2.22 ± 1.035
1.11AlaGly: 1.11 ± 0.874
0.555AlaHis: 0.555 ± 0.438
2.775AlaIle: 2.775 ± 0.821
4.994AlaLys: 4.994 ± 0.842
6.104AlaLeu: 6.104 ± 1.778
1.11AlaMet: 1.11 ± 0.548
2.22AlaAsn: 2.22 ± 0.945
4.44AlaPro: 4.44 ± 0.938
4.994AlaGln: 4.994 ± 1.304
3.33AlaArg: 3.33 ± 1.216
2.22AlaSer: 2.22 ± 1.183
4.44AlaThr: 4.44 ± 0.993
1.11AlaVal: 1.11 ± 0.72
1.11AlaTrp: 1.11 ± 0.875
2.775AlaTyr: 2.775 ± 1.157
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
1.11CysCys: 1.11 ± 0.862
0.555CysAsp: 0.555 ± 0.51
1.11CysGlu: 1.11 ± 0.548
1.665CysPhe: 1.665 ± 0.94
2.22CysGly: 2.22 ± 0.835
0.555CysHis: 0.555 ± 0.518
2.22CysIle: 2.22 ± 0.929
0.555CysLys: 0.555 ± 0.475
1.11CysLeu: 1.11 ± 0.6
1.11CysMet: 1.11 ± 0.72
2.775CysAsn: 2.775 ± 1.14
1.11CysPro: 1.11 ± 0.653
0.0CysGln: 0.0 ± 0.0
1.11CysArg: 1.11 ± 0.904
3.33CysSer: 3.33 ± 2.114
1.11CysThr: 1.11 ± 0.732
0.555CysVal: 0.555 ± 0.431
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
2.775AspAla: 2.775 ± 1.18
0.555AspCys: 0.555 ± 0.431
2.22AspAsp: 2.22 ± 0.836
1.665AspGlu: 1.665 ± 0.6
2.775AspPhe: 2.775 ± 0.89
3.33AspGly: 3.33 ± 1.3
1.665AspHis: 1.665 ± 0.718
2.22AspIle: 2.22 ± 1.041
1.665AspLys: 1.665 ± 0.928
4.44AspLeu: 4.44 ± 1.423
0.0AspMet: 0.0 ± 0.0
1.665AspAsn: 1.665 ± 0.841
2.775AspPro: 2.775 ± 0.843
1.11AspGln: 1.11 ± 0.74
2.775AspArg: 2.775 ± 1.16
5.549AspSer: 5.549 ± 0.942
1.665AspThr: 1.665 ± 0.665
5.549AspVal: 5.549 ± 1.391
0.555AspTrp: 0.555 ± 0.438
1.11AspTyr: 1.11 ± 0.875
0.0AspXaa: 0.0 ± 0.0
Glu
3.885GluAla: 3.885 ± 1.591
0.0GluCys: 0.0 ± 0.0
1.11GluAsp: 1.11 ± 0.558
3.33GluGlu: 3.33 ± 1.551
1.11GluPhe: 1.11 ± 0.875
3.885GluGly: 3.885 ± 1.252
1.11GluHis: 1.11 ± 0.862
1.11GluIle: 1.11 ± 0.775
1.665GluLys: 1.665 ± 0.934
4.44GluLeu: 4.44 ± 1.572
0.0GluMet: 0.0 ± 0.0
2.22GluAsn: 2.22 ± 1.562
1.11GluPro: 1.11 ± 0.637
2.775GluGln: 2.775 ± 1.062
2.775GluArg: 2.775 ± 1.272
3.33GluSer: 3.33 ± 1.05
4.44GluThr: 4.44 ± 2.132
0.555GluVal: 0.555 ± 0.642
0.555GluTrp: 0.555 ± 0.712
2.775GluTyr: 2.775 ± 1.238
0.0GluXaa: 0.0 ± 0.0
Phe
1.665PheAla: 1.665 ± 0.85
1.665PheCys: 1.665 ± 0.823
1.11PheAsp: 1.11 ± 0.591
1.665PheGlu: 1.665 ± 0.602
1.11PhePhe: 1.11 ± 0.558
2.22PheGly: 2.22 ± 1.054
2.22PheHis: 2.22 ± 0.954
1.11PheIle: 1.11 ± 0.593
3.885PheLys: 3.885 ± 1.219
3.885PheLeu: 3.885 ± 1.421
1.11PheMet: 1.11 ± 0.729
3.885PheAsn: 3.885 ± 0.922
4.44PhePro: 4.44 ± 1.756
1.665PheGln: 1.665 ± 1.05
2.775PheArg: 2.775 ± 1.756
1.665PheSer: 1.665 ± 0.863
2.775PheThr: 2.775 ± 1.097
2.775PheVal: 2.775 ± 2.037
0.555PheTrp: 0.555 ± 0.431
1.665PheTyr: 1.665 ± 0.979
0.0PheXaa: 0.0 ± 0.0
Gly
2.22GlyAla: 2.22 ± 0.982
2.775GlyCys: 2.775 ± 1.079
3.885GlyAsp: 3.885 ± 1.252
2.22GlyGlu: 2.22 ± 1.498
1.665GlyPhe: 1.665 ± 0.983
3.33GlyGly: 3.33 ± 1.459
1.11GlyHis: 1.11 ± 0.558
2.22GlyIle: 2.22 ± 0.702
4.994GlyLys: 4.994 ± 1.961
2.22GlyLeu: 2.22 ± 0.795
1.665GlyMet: 1.665 ± 1.143
2.22GlyAsn: 2.22 ± 1.582
3.885GlyPro: 3.885 ± 1.043
3.33GlyGln: 3.33 ± 1.563
4.44GlyArg: 4.44 ± 1.027
2.22GlySer: 2.22 ± 1.334
2.22GlyThr: 2.22 ± 0.627
3.33GlyVal: 3.33 ± 1.998
0.0GlyTrp: 0.0 ± 0.0
2.22GlyTyr: 2.22 ± 1.339
0.0GlyXaa: 0.0 ± 0.0
His
1.665HisAla: 1.665 ± 1.201
1.11HisCys: 1.11 ± 1.425
1.11HisAsp: 1.11 ± 0.637
2.775HisGlu: 2.775 ± 0.938
0.555HisPhe: 0.555 ± 0.438
2.22HisGly: 2.22 ± 1.243
2.775HisHis: 2.775 ± 1.516
2.22HisIle: 2.22 ± 0.943
2.22HisLys: 2.22 ± 0.975
2.775HisLeu: 2.775 ± 1.14
1.11HisMet: 1.11 ± 0.624
2.22HisAsn: 2.22 ± 0.95
1.11HisPro: 1.11 ± 0.593
2.22HisGln: 2.22 ± 1.649
3.33HisArg: 3.33 ± 1.555
2.22HisSer: 2.22 ± 1.287
2.22HisThr: 2.22 ± 1.444
3.33HisVal: 3.33 ± 0.989
0.0HisTrp: 0.0 ± 0.0
2.22HisTyr: 2.22 ± 0.904
0.0HisXaa: 0.0 ± 0.0
Ile
1.665IleAla: 1.665 ± 0.928
1.11IleCys: 1.11 ± 0.732
2.22IleAsp: 2.22 ± 1.044
2.775IleGlu: 2.775 ± 1.702
1.665IlePhe: 1.665 ± 0.866
0.555IleGly: 0.555 ± 0.431
2.775IleHis: 2.775 ± 2.172
1.11IleIle: 1.11 ± 1.036
5.549IleLys: 5.549 ± 0.988
4.994IleLeu: 4.994 ± 2.085
2.22IleMet: 2.22 ± 1.201
3.33IleAsn: 3.33 ± 0.986
1.11IlePro: 1.11 ± 0.783
1.11IleGln: 1.11 ± 0.775
4.44IleArg: 4.44 ± 1.2
4.994IleSer: 4.994 ± 1.69
4.44IleThr: 4.44 ± 1.434
3.33IleVal: 3.33 ± 1.386
1.11IleTrp: 1.11 ± 0.732
1.665IleTyr: 1.665 ± 0.723
0.0IleXaa: 0.0 ± 0.0
Lys
2.775LysAla: 2.775 ± 0.918
1.665LysCys: 1.665 ± 0.912
3.885LysAsp: 3.885 ± 1.529
3.33LysGlu: 3.33 ± 1.591
1.665LysPhe: 1.665 ± 0.926
2.22LysGly: 2.22 ± 1.374
2.775LysHis: 2.775 ± 1.011
2.22LysIle: 2.22 ± 1.198
3.885LysLys: 3.885 ± 1.627
6.104LysLeu: 6.104 ± 2.667
0.555LysMet: 0.555 ± 0.438
4.44LysAsn: 4.44 ± 1.223
7.214LysPro: 7.214 ± 2.332
2.775LysGln: 2.775 ± 0.964
3.33LysArg: 3.33 ± 1.328
3.885LysSer: 3.885 ± 1.425
3.33LysThr: 3.33 ± 1.08
4.44LysVal: 4.44 ± 1.351
0.0LysTrp: 0.0 ± 0.0
3.885LysTyr: 3.885 ± 0.972
0.0LysXaa: 0.0 ± 0.0
Leu
3.885LeuAla: 3.885 ± 1.189
1.665LeuCys: 1.665 ± 0.866
6.104LeuAsp: 6.104 ± 1.195
1.665LeuGlu: 1.665 ± 0.83
2.22LeuPhe: 2.22 ± 1.085
6.104LeuGly: 6.104 ± 1.862
2.775LeuHis: 2.775 ± 0.944
3.33LeuIle: 3.33 ± 1.852
7.769LeuLys: 7.769 ± 1.201
7.214LeuLeu: 7.214 ± 2.144
2.22LeuMet: 2.22 ± 1.152
5.549LeuAsn: 5.549 ± 1.87
2.775LeuPro: 2.775 ± 1.027
3.33LeuGln: 3.33 ± 1.411
5.549LeuArg: 5.549 ± 1.577
7.769LeuSer: 7.769 ± 1.757
6.104LeuThr: 6.104 ± 1.391
3.33LeuVal: 3.33 ± 0.953
1.11LeuTrp: 1.11 ± 0.801
2.22LeuTyr: 2.22 ± 1.181
0.0LeuXaa: 0.0 ± 0.0
Met
1.11MetAla: 1.11 ± 0.637
0.0MetCys: 0.0 ± 0.0
3.885MetAsp: 3.885 ± 1.066
1.665MetGlu: 1.665 ± 1.283
2.22MetPhe: 2.22 ± 0.905
1.11MetGly: 1.11 ± 0.653
1.11MetHis: 1.11 ± 0.6
0.0MetIle: 0.0 ± 0.0
1.11MetLys: 1.11 ± 0.63
3.33MetLeu: 3.33 ± 1.483
1.11MetMet: 1.11 ± 1.015
0.555MetAsn: 0.555 ± 0.475
1.11MetPro: 1.11 ± 0.782
1.665MetGln: 1.665 ± 0.862
1.665MetArg: 1.665 ± 0.841
1.11MetSer: 1.11 ± 0.651
0.555MetThr: 0.555 ± 0.431
1.11MetVal: 1.11 ± 1.036
1.11MetTrp: 1.11 ± 0.653
1.11MetTyr: 1.11 ± 0.591
0.0MetXaa: 0.0 ± 0.0
Asn
6.104AsnAla: 6.104 ± 1.173
1.665AsnCys: 1.665 ± 0.762
2.775AsnAsp: 2.775 ± 0.838
1.665AsnGlu: 1.665 ± 0.665
1.665AsnPhe: 1.665 ± 0.895
1.665AsnGly: 1.665 ± 0.846
3.33AsnHis: 3.33 ± 1.981
2.22AsnIle: 2.22 ± 0.788
2.775AsnLys: 2.775 ± 1.018
2.775AsnLeu: 2.775 ± 1.466
2.775AsnMet: 2.775 ± 1.079
3.885AsnAsn: 3.885 ± 0.947
3.33AsnPro: 3.33 ± 0.993
3.33AsnGln: 3.33 ± 1.11
3.33AsnArg: 3.33 ± 1.611
2.775AsnSer: 2.775 ± 0.778
1.11AsnThr: 1.11 ± 0.881
8.324AsnVal: 8.324 ± 1.923
0.0AsnTrp: 0.0 ± 0.0
3.885AsnTyr: 3.885 ± 0.992
0.0AsnXaa: 0.0 ± 0.0
Pro
1.665ProAla: 1.665 ± 1.012
1.11ProCys: 1.11 ± 0.651
1.665ProAsp: 1.665 ± 0.841
2.775ProGlu: 2.775 ± 0.776
3.885ProPhe: 3.885 ± 1.418
5.549ProGly: 5.549 ± 1.846
4.994ProHis: 4.994 ± 2.393
3.885ProIle: 3.885 ± 1.743
2.22ProLys: 2.22 ± 1.374
7.214ProLeu: 7.214 ± 2.269
1.665ProMet: 1.665 ± 0.987
2.22ProAsn: 2.22 ± 1.159
2.775ProPro: 2.775 ± 0.897
0.555ProGln: 0.555 ± 0.642
3.885ProArg: 3.885 ± 1.19
4.44ProSer: 4.44 ± 2.753
4.994ProThr: 4.994 ± 1.745
2.775ProVal: 2.775 ± 0.762
0.555ProTrp: 0.555 ± 0.431
1.11ProTyr: 1.11 ± 1.076
0.0ProXaa: 0.0 ± 0.0
Gln
2.775GlnAla: 2.775 ± 0.863
0.0GlnCys: 0.0 ± 0.0
1.11GlnAsp: 1.11 ± 0.79
2.22GlnGlu: 2.22 ± 1.144
2.22GlnPhe: 2.22 ± 0.831
0.555GlnGly: 0.555 ± 0.538
2.775GlnHis: 2.775 ± 1.218
1.665GlnIle: 1.665 ± 0.783
0.555GlnLys: 0.555 ± 0.604
3.885GlnLeu: 3.885 ± 1.3
0.555GlnMet: 0.555 ± 0.642
2.22GlnAsn: 2.22 ± 0.919
2.22GlnPro: 2.22 ± 0.983
1.11GlnGln: 1.11 ± 0.874
3.885GlnArg: 3.885 ± 0.784
4.44GlnSer: 4.44 ± 2.113
3.885GlnThr: 3.885 ± 1.426
3.33GlnVal: 3.33 ± 1.199
0.555GlnTrp: 0.555 ± 0.51
1.11GlnTyr: 1.11 ± 0.591
0.0GlnXaa: 0.0 ± 0.0
Arg
2.775ArgAla: 2.775 ± 1.15
2.775ArgCys: 2.775 ± 1.301
2.775ArgAsp: 2.775 ± 0.906
1.11ArgGlu: 1.11 ± 0.783
6.104ArgPhe: 6.104 ± 1.701
3.33ArgGly: 3.33 ± 1.182
1.665ArgHis: 1.665 ± 0.6
4.994ArgIle: 4.994 ± 1.045
3.33ArgLys: 3.33 ± 1.541
5.549ArgLeu: 5.549 ± 1.596
0.555ArgMet: 0.555 ± 0.431
3.885ArgAsn: 3.885 ± 1.939
4.44ArgPro: 4.44 ± 1.124
1.665ArgGln: 1.665 ± 0.751
5.549ArgArg: 5.549 ± 1.861
6.659ArgSer: 6.659 ± 1.226
3.885ArgThr: 3.885 ± 1.31
2.775ArgVal: 2.775 ± 1.16
0.0ArgTrp: 0.0 ± 0.0
2.22ArgTyr: 2.22 ± 0.978
0.0ArgXaa: 0.0 ± 0.0
Ser
7.214SerAla: 7.214 ± 2.687
1.665SerCys: 1.665 ± 0.803
1.665SerAsp: 1.665 ± 0.681
1.665SerGlu: 1.665 ± 0.718
2.22SerPhe: 2.22 ± 0.788
2.775SerGly: 2.775 ± 1.324
2.22SerHis: 2.22 ± 0.788
2.775SerIle: 2.775 ± 1.387
7.214SerLys: 7.214 ± 1.995
4.994SerLeu: 4.994 ± 1.78
3.33SerMet: 3.33 ± 2.014
6.104SerAsn: 6.104 ± 1.148
4.44SerPro: 4.44 ± 1.42
2.775SerGln: 2.775 ± 1.377
2.22SerArg: 2.22 ± 0.838
7.214SerSer: 7.214 ± 2.387
3.885SerThr: 3.885 ± 1.212
5.549SerVal: 5.549 ± 1.067
1.11SerTrp: 1.11 ± 0.591
2.775SerTyr: 2.775 ± 1.018
0.0SerXaa: 0.0 ± 0.0
Thr
2.22ThrAla: 2.22 ± 1.563
2.22ThrCys: 2.22 ± 1.431
1.11ThrAsp: 1.11 ± 0.72
1.665ThrGlu: 1.665 ± 0.758
3.885ThrPhe: 3.885 ± 1.015
3.885ThrGly: 3.885 ± 0.908
2.22ThrHis: 2.22 ± 1.148
6.659ThrIle: 6.659 ± 2.047
2.775ThrLys: 2.775 ± 1.323
2.775ThrLeu: 2.775 ± 1.534
1.665ThrMet: 1.665 ± 0.932
3.33ThrAsn: 3.33 ± 1.084
6.104ThrPro: 6.104 ± 1.958
2.775ThrGln: 2.775 ± 0.871
4.44ThrArg: 4.44 ± 0.752
2.22ThrSer: 2.22 ± 0.869
4.994ThrThr: 4.994 ± 2.174
3.33ThrVal: 3.33 ± 1.783
1.665ThrTrp: 1.665 ± 1.321
0.555ThrTyr: 0.555 ± 0.438
0.0ThrXaa: 0.0 ± 0.0
Val
0.555ValAla: 0.555 ± 0.51
0.0ValCys: 0.0 ± 0.0
3.885ValAsp: 3.885 ± 1.681
2.775ValGlu: 2.775 ± 1.469
2.775ValPhe: 2.775 ± 1.429
3.33ValGly: 3.33 ± 1.334
1.665ValHis: 1.665 ± 0.937
6.104ValIle: 6.104 ± 1.132
5.549ValLys: 5.549 ± 1.57
5.549ValLeu: 5.549 ± 1.842
1.11ValMet: 1.11 ± 0.685
4.994ValAsn: 4.994 ± 1.318
3.33ValPro: 3.33 ± 1.205
2.775ValGln: 2.775 ± 0.821
3.33ValArg: 3.33 ± 1.102
3.885ValSer: 3.885 ± 1.153
3.33ValThr: 3.33 ± 1.116
2.775ValVal: 2.775 ± 0.982
0.0ValTrp: 0.0 ± 0.0
3.33ValTyr: 3.33 ± 1.501
0.0ValXaa: 0.0 ± 0.0
Trp
3.885TrpAla: 3.885 ± 1.103
0.0TrpCys: 0.0 ± 0.0
1.11TrpAsp: 1.11 ± 0.758
0.555TrpGlu: 0.555 ± 0.431
0.0TrpPhe: 0.0 ± 0.0
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
0.555TrpIle: 0.555 ± 0.51
0.0TrpLys: 0.0 ± 0.0
0.0TrpLeu: 0.0 ± 0.0
0.555TrpMet: 0.555 ± 0.475
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
0.555TrpGln: 0.555 ± 0.438
1.11TrpArg: 1.11 ± 0.862
0.555TrpSer: 0.555 ± 0.431
0.0TrpThr: 0.0 ± 0.0
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
1.11TrpTyr: 1.11 ± 0.782
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.885TyrAla: 3.885 ± 1.433
0.0TyrCys: 0.0 ± 0.0
2.775TyrAsp: 2.775 ± 1.551
0.555TyrGlu: 0.555 ± 0.475
2.22TyrPhe: 2.22 ± 0.825
2.775TyrGly: 2.775 ± 0.843
1.11TyrHis: 1.11 ± 0.593
2.775TyrIle: 2.775 ± 0.613
1.665TyrLys: 1.665 ± 0.59
3.885TyrLeu: 3.885 ± 1.486
1.665TyrMet: 1.665 ± 0.865
1.665TyrAsn: 1.665 ± 0.723
2.22TyrPro: 2.22 ± 0.993
0.555TyrGln: 0.555 ± 0.475
2.775TyrArg: 2.775 ± 1.451
3.33TyrSer: 3.33 ± 1.106
1.11TyrThr: 1.11 ± 0.593
2.775TyrVal: 2.775 ± 1.144
0.0TyrTrp: 0.0 ± 0.0
1.665TyrTyr: 1.665 ± 0.853
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 9 proteins (1803 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski