Amino acid dipepetide frequency for Rhinolophus ferrumequinum (Greater horseshoe bat)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	7.047AlaAla: 7.047 ± 0.033	1.379AlaCys: 1.379 ± 0.012	2.958AlaAsp: 2.958 ± 0.013	4.87AlaGlu: 4.87 ± 0.026	2.576AlaPhe: 2.576 ± 0.016	4.84AlaGly: 4.84 ± 0.026	1.544AlaHis: 1.544 ± 0.009	2.759AlaIle: 2.759 ± 0.013	3.428AlaLys: 3.428 ± 0.022	7.151AlaLeu: 7.151 ± 0.031	1.496AlaMet: 1.496 ± 0.009	2.026AlaAsn: 2.026 ± 0.012	4.355AlaPro: 4.355 ± 0.027	3.284AlaGln: 3.284 ± 0.018	3.773AlaArg: 3.773 ± 0.018	5.824AlaSer: 5.824 ± 0.021	3.6AlaThr: 3.6 ± 0.019	4.756AlaVal: 4.756 ± 0.016	0.79AlaTrp: 0.79 ± 0.007	1.514AlaTyr: 1.514 ± 0.009	0.0AlaXaa: 0.0 ± 0.0
Cys	1.256CysAla: 1.256 ± 0.01	0.625CysCys: 0.625 ± 0.012	0.997CysAsp: 0.997 ± 0.011	1.261CysGlu: 1.261 ± 0.012	0.81CysPhe: 0.81 ± 0.008	1.673CysGly: 1.673 ± 0.018	0.662CysHis: 0.662 ± 0.007	0.92CysIle: 0.92 ± 0.008	1.124CysLys: 1.124 ± 0.01	2.099CysLeu: 2.099 ± 0.013	0.401CysMet: 0.401 ± 0.004	0.783CysAsn: 0.783 ± 0.008	1.376CysPro: 1.376 ± 0.016	1.056CysGln: 1.056 ± 0.01	1.281CysArg: 1.281 ± 0.011	1.945CysSer: 1.945 ± 0.015	1.09CysThr: 1.09 ± 0.008	1.303CysVal: 1.303 ± 0.011	0.286CysTrp: 0.286 ± 0.004	0.568CysTyr: 0.568 ± 0.006	0.0CysXaa: 0.0 ± 0.0
Asp	2.881AspAla: 2.881 ± 0.015	1.031AspCys: 1.031 ± 0.011	2.698AspAsp: 2.698 ± 0.016	3.49AspGlu: 3.49 ± 0.016	2.112AspPhe: 2.112 ± 0.012	3.366AspGly: 3.366 ± 0.024	1.118AspHis: 1.118 ± 0.009	2.597AspIle: 2.597 ± 0.014	2.536AspLys: 2.536 ± 0.014	4.969AspLeu: 4.969 ± 0.017	1.124AspMet: 1.124 ± 0.008	1.683AspAsn: 1.683 ± 0.01	2.922AspPro: 2.922 ± 0.015	1.822AspGln: 1.822 ± 0.012	2.463AspArg: 2.463 ± 0.013	4.232AspSer: 4.232 ± 0.018	2.522AspThr: 2.522 ± 0.013	3.12AspVal: 3.12 ± 0.02	0.614AspTrp: 0.614 ± 0.006	1.469AspTyr: 1.469 ± 0.009	0.0AspXaa: 0.0 ± 0.0
Glu	5.282GluAla: 5.282 ± 0.027	1.388GluCys: 1.388 ± 0.017	4.437GluAsp: 4.437 ± 0.021	7.883GluGlu: 7.883 ± 0.043	2.026GluPhe: 2.026 ± 0.011	4.235GluGly: 4.235 ± 0.023	1.517GluHis: 1.517 ± 0.01	3.145GluIle: 3.145 ± 0.025	5.452GluLys: 5.452 ± 0.032	6.492GluLeu: 6.492 ± 0.033	1.676GluMet: 1.676 ± 0.011	3.135GluAsn: 3.135 ± 0.019	3.36GluPro: 3.36 ± 0.026	3.173GluGln: 3.173 ± 0.021	4.106GluArg: 4.106 ± 0.021	4.416GluSer: 4.416 ± 0.018	3.445GluThr: 3.445 ± 0.016	4.194GluVal: 4.194 ± 0.025	0.699GluTrp: 0.699 ± 0.006	1.612GluTyr: 1.612 ± 0.019	0.0GluXaa: 0.0 ± 0.0
Phe	1.954PheAla: 1.954 ± 0.013	0.89PheCys: 0.89 ± 0.009	1.663PheAsp: 1.663 ± 0.012	1.992PheGlu: 1.992 ± 0.012	1.544PhePhe: 1.544 ± 0.011	2.168PheGly: 2.168 ± 0.015	1.039PheHis: 1.039 ± 0.008	1.789PheIle: 1.789 ± 0.013	1.772PheLys: 1.772 ± 0.013	4.009PheLeu: 4.009 ± 0.023	0.765PheMet: 0.765 ± 0.007	1.317PheAsn: 1.317 ± 0.01	2.0PhePro: 2.0 ± 0.014	1.789PheGln: 1.789 ± 0.012	1.983PheArg: 1.983 ± 0.017	3.37PheSer: 3.37 ± 0.018	2.007PheThr: 2.007 ± 0.012	2.129PheVal: 2.129 ± 0.014	0.489PheTrp: 0.489 ± 0.006	1.149PheTyr: 1.149 ± 0.01	0.0PheXaa: 0.0 ± 0.0
Gly	4.634GlyAla: 4.634 ± 0.029	1.271GlyCys: 1.271 ± 0.013	3.173GlyAsp: 3.173 ± 0.02	4.126GlyGlu: 4.126 ± 0.024	2.371GlyPhe: 2.371 ± 0.018	5.142GlyGly: 5.142 ± 0.034	1.698GlyHis: 1.698 ± 0.012	2.682GlyIle: 2.682 ± 0.013	3.774GlyLys: 3.774 ± 0.02	5.915GlyLeu: 5.915 ± 0.028	1.281GlyMet: 1.281 ± 0.01	2.356GlyAsn: 2.356 ± 0.013	4.439GlyPro: 4.439 ± 0.042	2.753GlyGln: 2.753 ± 0.018	3.852GlyArg: 3.852 ± 0.02	5.899GlySer: 5.899 ± 0.027	3.675GlyThr: 3.675 ± 0.016	3.6GlyVal: 3.6 ± 0.018	0.791GlyTrp: 0.791 ± 0.008	1.722GlyTyr: 1.722 ± 0.013	0.0GlyXaa: 0.0 ± 0.0
His	1.319HisAla: 1.319 ± 0.008	0.708HisCys: 0.708 ± 0.007	0.894HisAsp: 0.894 ± 0.007	1.308HisGlu: 1.308 ± 0.009	1.062HisPhe: 1.062 ± 0.009	1.54HisGly: 1.54 ± 0.011	0.888HisHis: 0.888 ± 0.009	1.221HisIle: 1.221 ± 0.007	1.24HisLys: 1.24 ± 0.009	2.897HisLeu: 2.897 ± 0.017	0.587HisMet: 0.587 ± 0.006	0.857HisAsn: 0.857 ± 0.008	1.663HisPro: 1.663 ± 0.012	1.328HisGln: 1.328 ± 0.011	1.603HisArg: 1.603 ± 0.011	2.289HisSer: 2.289 ± 0.016	1.483HisThr: 1.483 ± 0.014	1.541HisVal: 1.541 ± 0.009	0.337HisTrp: 0.337 ± 0.004	0.794HisTyr: 0.794 ± 0.008	0.0HisXaa: 0.0 ± 0.0
Ile	2.561IleAla: 2.561 ± 0.013	1.027IleCys: 1.027 ± 0.009	1.986IleAsp: 1.986 ± 0.013	2.589IleGlu: 2.589 ± 0.022	1.842IlePhe: 1.842 ± 0.014	2.158IleGly: 2.158 ± 0.011	1.298IleHis: 1.298 ± 0.011	2.305IleIle: 2.305 ± 0.018	2.601IleLys: 2.601 ± 0.023	4.434IleLeu: 4.434 ± 0.022	0.963IleMet: 0.963 ± 0.007	1.801IleAsn: 1.801 ± 0.012	2.573IlePro: 2.573 ± 0.015	2.254IleGln: 2.254 ± 0.012	2.36IleArg: 2.36 ± 0.011	3.638IleSer: 3.638 ± 0.02	2.566IleThr: 2.566 ± 0.023	2.517IleVal: 2.517 ± 0.019	0.494IleTrp: 0.494 ± 0.006	1.356IleTyr: 1.356 ± 0.01	0.0IleXaa: 0.0 ± 0.0
Lys	3.993LysAla: 3.993 ± 0.024	1.114LysCys: 1.114 ± 0.01	3.187LysAsp: 3.187 ± 0.021	5.138LysGlu: 5.138 ± 0.026	1.716LysPhe: 1.716 ± 0.013	3.282LysGly: 3.282 ± 0.027	1.398LysHis: 1.398 ± 0.009	2.706LysIle: 2.706 ± 0.018	4.713LysLys: 4.713 ± 0.03	5.179LysLeu: 5.179 ± 0.022	1.429LysMet: 1.429 ± 0.012	2.394LysAsn: 2.394 ± 0.014	3.137LysPro: 3.137 ± 0.026	2.612LysGln: 2.612 ± 0.017	3.306LysArg: 3.306 ± 0.016	3.917LysSer: 3.917 ± 0.02	3.112LysThr: 3.112 ± 0.018	3.503LysVal: 3.503 ± 0.031	0.615LysTrp: 0.615 ± 0.007	1.547LysTyr: 1.547 ± 0.015	0.0LysXaa: 0.0 ± 0.0
Leu	6.754LeuAla: 6.754 ± 0.032	2.163LeuCys: 2.163 ± 0.017	4.737LeuAsp: 4.737 ± 0.019	7.218LeuGlu: 7.218 ± 0.034	3.34LeuPhe: 3.34 ± 0.021	5.869LeuGly: 5.869 ± 0.029	2.706LeuHis: 2.706 ± 0.016	3.782LeuIle: 3.782 ± 0.019	5.785LeuLys: 5.785 ± 0.027	10.704LeuLeu: 10.704 ± 0.054	1.951LeuMet: 1.951 ± 0.011	3.443LeuAsn: 3.443 ± 0.017	6.033LeuPro: 6.033 ± 0.027	5.786LeuGln: 5.786 ± 0.03	5.959LeuArg: 5.959 ± 0.029	8.03LeuSer: 8.03 ± 0.027	5.099LeuThr: 5.099 ± 0.02	5.486LeuVal: 5.486 ± 0.025	1.114LeuTrp: 1.114 ± 0.008	2.499LeuTyr: 2.499 ± 0.017	0.0LeuXaa: 0.0 ± 0.0
Met	1.939MetAla: 1.939 ± 0.011	0.384MetCys: 0.384 ± 0.005	1.259MetAsp: 1.259 ± 0.01	1.85MetGlu: 1.85 ± 0.012	0.709MetPhe: 0.709 ± 0.007	1.272MetGly: 1.272 ± 0.01	0.451MetHis: 0.451 ± 0.005	0.804MetIle: 0.804 ± 0.008	1.439MetLys: 1.439 ± 0.01	1.936MetLeu: 1.936 ± 0.012	0.55MetMet: 0.55 ± 0.007	0.876MetAsn: 0.876 ± 0.01	1.095MetPro: 1.095 ± 0.013	0.921MetGln: 0.921 ± 0.008	1.029MetArg: 1.029 ± 0.008	1.577MetSer: 1.577 ± 0.011	1.125MetThr: 1.125 ± 0.009	1.376MetVal: 1.376 ± 0.01	0.235MetTrp: 0.235 ± 0.003	0.564MetTyr: 0.564 ± 0.006	0.0MetXaa: 0.0 ± 0.0
Asn	2.04AsnAla: 2.04 ± 0.01	0.807AsnCys: 0.807 ± 0.008	1.512AsnAsp: 1.512 ± 0.01	2.212AsnGlu: 2.212 ± 0.012	1.457AsnPhe: 1.457 ± 0.01	2.464AsnGly: 2.464 ± 0.016	0.933AsnHis: 0.933 ± 0.008	2.054AsnIle: 2.054 ± 0.012	2.189AsnLys: 2.189 ± 0.013	3.656AsnLeu: 3.656 ± 0.018	0.887AsnMet: 0.887 ± 0.008	1.515AsnAsn: 1.515 ± 0.01	2.154AsnPro: 2.154 ± 0.013	1.654AsnGln: 1.654 ± 0.012	1.829AsnArg: 1.829 ± 0.011	3.117AsnSer: 3.117 ± 0.018	1.955AsnThr: 1.955 ± 0.013	2.224AsnVal: 2.224 ± 0.015	0.444AsnTrp: 0.444 ± 0.005	1.101AsnTyr: 1.101 ± 0.008	0.0AsnXaa: 0.0 ± 0.0
Pro	5.084ProAla: 5.084 ± 0.029	1.125ProCys: 1.125 ± 0.012	2.824ProAsp: 2.824 ± 0.015	4.519ProGlu: 4.519 ± 0.028	1.925ProPhe: 1.925 ± 0.012	5.459ProGly: 5.459 ± 0.051	1.47ProHis: 1.47 ± 0.013	1.892ProIle: 1.892 ± 0.018	2.841ProLys: 2.841 ± 0.026	5.295ProLeu: 5.295 ± 0.024	1.035ProMet: 1.035 ± 0.009	1.82ProAsn: 1.82 ± 0.012	6.366ProPro: 6.366 ± 0.051	2.857ProGln: 2.857 ± 0.018	3.443ProArg: 3.443 ± 0.019	5.888ProSer: 5.888 ± 0.029	3.206ProThr: 3.206 ± 0.021	3.908ProVal: 3.908 ± 0.022	0.692ProTrp: 0.692 ± 0.007	1.488ProTyr: 1.488 ± 0.011	0.0ProXaa: 0.0 ± 0.0
Gln	3.533GlnAla: 3.533 ± 0.023	0.915GlnCys: 0.915 ± 0.009	2.36GlnAsp: 2.36 ± 0.012	3.934GlnGlu: 3.934 ± 0.021	1.354GlnPhe: 1.354 ± 0.008	2.849GlnGly: 2.849 ± 0.018	1.297GlnHis: 1.297 ± 0.011	1.953GlnIle: 1.953 ± 0.011	2.943GlnLys: 2.943 ± 0.019	4.758GlnLeu: 4.758 ± 0.027	1.118GlnMet: 1.118 ± 0.008	1.836GlnAsn: 1.836 ± 0.013	2.835GlnPro: 2.835 ± 0.02	3.049GlnGln: 3.049 ± 0.031	2.993GlnArg: 2.993 ± 0.021	3.147GlnSer: 3.147 ± 0.02	2.294GlnThr: 2.294 ± 0.013	2.835GlnVal: 2.835 ± 0.016	0.534GlnTrp: 0.534 ± 0.006	1.145GlnTyr: 1.145 ± 0.009	0.0GlnXaa: 0.0 ± 0.0
Arg	3.953ArgAla: 3.953 ± 0.017	1.201ArgCys: 1.201 ± 0.011	2.769ArgAsp: 2.769 ± 0.015	4.061ArgGlu: 4.061 ± 0.023	1.824ArgPhe: 1.824 ± 0.012	3.674ArgGly: 3.674 ± 0.025	1.534ArgHis: 1.534 ± 0.011	2.388ArgIle: 2.388 ± 0.014	3.692ArgLys: 3.692 ± 0.016	5.483ArgLeu: 5.483 ± 0.024	1.186ArgMet: 1.186 ± 0.008	2.113ArgAsn: 2.113 ± 0.012	3.367ArgPro: 3.367 ± 0.02	2.659ArgGln: 2.659 ± 0.017	4.411ArgArg: 4.411 ± 0.026	4.335ArgSer: 4.335 ± 0.028	2.868ArgThr: 2.868 ± 0.013	3.226ArgVal: 3.226 ± 0.021	0.704ArgTrp: 0.704 ± 0.006	1.443ArgTyr: 1.443 ± 0.01	0.0ArgXaa: 0.0 ± 0.0
Ser	5.46SerAla: 5.46 ± 0.02	1.838SerCys: 1.838 ± 0.014	3.957SerAsp: 3.957 ± 0.022	5.271SerGlu: 5.271 ± 0.023	3.006SerPhe: 3.006 ± 0.014	5.746SerGly: 5.746 ± 0.027	2.097SerHis: 2.097 ± 0.012	3.156SerIle: 3.156 ± 0.016	4.071SerLys: 4.071 ± 0.02	8.208SerLeu: 8.208 ± 0.031	1.592SerMet: 1.592 ± 0.01	2.64SerAsn: 2.64 ± 0.016	6.206SerPro: 6.206 ± 0.036	3.892SerGln: 3.892 ± 0.023	4.604SerArg: 4.604 ± 0.024	9.505SerSer: 9.505 ± 0.049	4.483SerThr: 4.483 ± 0.022	4.965SerVal: 4.965 ± 0.02	1.076SerTrp: 1.076 ± 0.009	2.045SerTyr: 2.045 ± 0.012	0.0SerXaa: 0.0 ± 0.0
Thr	3.831ThrAla: 3.831 ± 0.017	1.298ThrCys: 1.298 ± 0.014	2.495ThrAsp: 2.495 ± 0.014	3.577ThrGlu: 3.577 ± 0.018	2.112ThrPhe: 2.112 ± 0.014	3.589ThrGly: 3.589 ± 0.02	1.292ThrHis: 1.292 ± 0.01	2.356ThrIle: 2.356 ± 0.016	2.687ThrLys: 2.687 ± 0.021	5.287ThrLeu: 5.287 ± 0.02	1.115ThrMet: 1.115 ± 0.008	1.743ThrAsn: 1.743 ± 0.011	3.668ThrPro: 3.668 ± 0.024	2.286ThrGln: 2.286 ± 0.012	2.483ThrArg: 2.483 ± 0.012	4.707ThrSer: 4.707 ± 0.021	2.988ThrThr: 2.988 ± 0.029	3.905ThrVal: 3.905 ± 0.025	0.707ThrTrp: 0.707 ± 0.011	1.432ThrTyr: 1.432 ± 0.009	0.0ThrXaa: 0.0 ± 0.0
Val	4.281ValAla: 4.281 ± 0.019	1.436ValCys: 1.436 ± 0.011	2.95ValAsp: 2.95 ± 0.018	3.855ValGlu: 3.855 ± 0.025	2.379ValPhe: 2.379 ± 0.014	3.452ValGly: 3.452 ± 0.017	1.58ValHis: 1.58 ± 0.011	2.919ValIle: 2.919 ± 0.018	3.426ValLys: 3.426 ± 0.028	6.214ValLeu: 6.214 ± 0.022	1.317ValMet: 1.317 ± 0.009	2.26ValAsn: 2.26 ± 0.015	3.769ValPro: 3.769 ± 0.025	2.735ValGln: 2.735 ± 0.013	3.093ValArg: 3.093 ± 0.014	4.965ValSer: 4.965 ± 0.025	3.892ValThr: 3.892 ± 0.035	4.005ValVal: 4.005 ± 0.021	0.721ValTrp: 0.721 ± 0.007	1.614ValTyr: 1.614 ± 0.011	0.0ValXaa: 0.0 ± 0.0
Trp	0.784TrpAla: 0.784 ± 0.006	0.241TrpCys: 0.241 ± 0.004	0.642TrpAsp: 0.642 ± 0.006	0.809TrpGlu: 0.809 ± 0.006	0.442TrpPhe: 0.442 ± 0.006	0.737TrpGly: 0.737 ± 0.008	0.298TrpHis: 0.298 ± 0.004	0.538TrpIle: 0.538 ± 0.007	0.812TrpLys: 0.812 ± 0.007	1.185TrpLeu: 1.185 ± 0.009	0.318TrpMet: 0.318 ± 0.004	0.533TrpAsn: 0.533 ± 0.006	0.526TrpPro: 0.526 ± 0.006	0.527TrpGln: 0.527 ± 0.006	0.728TrpArg: 0.728 ± 0.007	0.859TrpSer: 0.859 ± 0.007	0.677TrpThr: 0.677 ± 0.008	0.702TrpVal: 0.702 ± 0.006	0.193TrpTrp: 0.193 ± 0.003	0.338TrpTyr: 0.338 ± 0.006	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.383TyrAla: 1.383 ± 0.009	0.674TyrCys: 0.674 ± 0.007	1.27TyrAsp: 1.27 ± 0.009	1.708TyrGlu: 1.708 ± 0.013	1.211TyrPhe: 1.211 ± 0.009	1.64TyrGly: 1.64 ± 0.012	0.738TyrHis: 0.738 ± 0.007	1.358TyrIle: 1.358 ± 0.012	1.476TyrLys: 1.476 ± 0.015	2.587TyrLeu: 2.587 ± 0.014	0.6TyrMet: 0.6 ± 0.006	1.072TyrAsn: 1.072 ± 0.01	1.293TyrPro: 1.293 ± 0.011	1.245TyrGln: 1.245 ± 0.009	1.588TyrArg: 1.588 ± 0.01	2.162TyrSer: 2.162 ± 0.013	1.473TyrThr: 1.473 ± 0.014	1.568TyrVal: 1.568 ± 0.012	0.353TyrTrp: 0.353 ± 0.005	0.933TyrTyr: 0.933 ± 0.008	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 33504 proteins (19587673 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

---