Amino acid dipepetide frequency for Batrachochytrium dendrobatidis (strain JAM81 / FGSC 10211) (Frog chytrid fungus)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.004AlaAla: 6.004 ± 0.059
1.056AlaCys: 1.056 ± 0.016
3.612AlaAsp: 3.612 ± 0.033
3.572AlaGlu: 3.572 ± 0.037
2.751AlaPhe: 2.751 ± 0.028
3.679AlaGly: 3.679 ± 0.039
1.689AlaHis: 1.689 ± 0.023
4.708AlaIle: 4.708 ± 0.037
3.927AlaLys: 3.927 ± 0.039
6.668AlaLeu: 6.668 ± 0.051
1.782AlaMet: 1.782 ± 0.023
3.08AlaAsn: 3.08 ± 0.03
2.888AlaPro: 2.888 ± 0.044
2.831AlaGln: 2.831 ± 0.041
3.04AlaArg: 3.04 ± 0.029
6.723AlaSer: 6.723 ± 0.054
4.69AlaThr: 4.69 ± 0.039
4.634AlaVal: 4.634 ± 0.04
0.694AlaTrp: 0.694 ± 0.014
1.88AlaTyr: 1.88 ± 0.024
0.0AlaXaa: 0.0 ± 0.0
Cys
0.859CysAla: 0.859 ± 0.016
0.298CysCys: 0.298 ± 0.012
0.783CysAsp: 0.783 ± 0.015
0.69CysGlu: 0.69 ± 0.014
0.684CysPhe: 0.684 ± 0.014
0.966CysGly: 0.966 ± 0.025
0.409CysHis: 0.409 ± 0.011
1.132CysIle: 1.132 ± 0.015
0.816CysLys: 0.816 ± 0.015
1.391CysLeu: 1.391 ± 0.021
0.395CysMet: 0.395 ± 0.011
0.699CysAsn: 0.699 ± 0.015
0.633CysPro: 0.633 ± 0.014
0.585CysGln: 0.585 ± 0.013
0.712CysArg: 0.712 ± 0.015
1.306CysSer: 1.306 ± 0.022
0.887CysThr: 0.887 ± 0.016
0.931CysVal: 0.931 ± 0.017
0.17CysTrp: 0.17 ± 0.007
0.429CysTyr: 0.429 ± 0.012
0.0CysXaa: 0.0 ± 0.0
Asp
4.147AspAla: 4.147 ± 0.039
0.775AspCys: 0.775 ± 0.017
3.536AspAsp: 3.536 ± 0.041
3.583AspGlu: 3.583 ± 0.037
2.153AspPhe: 2.153 ± 0.028
3.18AspGly: 3.18 ± 0.03
1.407AspHis: 1.407 ± 0.017
3.972AspIle: 3.972 ± 0.036
2.648AspLys: 2.648 ± 0.031
5.265AspLeu: 5.265 ± 0.042
1.613AspMet: 1.613 ± 0.021
2.134AspAsn: 2.134 ± 0.025
2.757AspPro: 2.757 ± 0.026
2.493AspGln: 2.493 ± 0.03
2.625AspArg: 2.625 ± 0.03
5.04AspSer: 5.04 ± 0.045
3.624AspThr: 3.624 ± 0.035
3.37AspVal: 3.37 ± 0.031
0.68AspTrp: 0.68 ± 0.014
1.711AspTyr: 1.711 ± 0.021
0.0AspXaa: 0.0 ± 0.0
Glu
3.566GluAla: 3.566 ± 0.036
0.853GluCys: 0.853 ± 0.017
2.827GluAsp: 2.827 ± 0.032
3.292GluGlu: 3.292 ± 0.04
2.251GluPhe: 2.251 ± 0.023
2.059GluGly: 2.059 ± 0.027
1.46GluHis: 1.46 ± 0.021
3.468GluIle: 3.468 ± 0.031
3.581GluLys: 3.581 ± 0.04
5.493GluLeu: 5.493 ± 0.042
1.528GluMet: 1.528 ± 0.02
2.556GluAsn: 2.556 ± 0.029
2.154GluPro: 2.154 ± 0.03
2.57GluGln: 2.57 ± 0.035
2.681GluArg: 2.681 ± 0.032
5.155GluSer: 5.155 ± 0.038
3.387GluThr: 3.387 ± 0.035
2.631GluVal: 2.631 ± 0.029
0.646GluTrp: 0.646 ± 0.014
1.902GluTyr: 1.902 ± 0.021
0.0GluXaa: 0.0 ± 0.0
Phe
2.554PheAla: 2.554 ± 0.027
0.603PheCys: 0.603 ± 0.012
2.573PheAsp: 2.573 ± 0.028
2.51PheGlu: 2.51 ± 0.03
1.555PhePhe: 1.555 ± 0.024
2.787PheGly: 2.787 ± 0.03
0.951PheHis: 0.951 ± 0.016
2.361PheIle: 2.361 ± 0.028
2.384PheLys: 2.384 ± 0.026
3.384PheLeu: 3.384 ± 0.033
0.937PheMet: 0.937 ± 0.014
1.778PheAsn: 1.778 ± 0.02
1.733PhePro: 1.733 ± 0.022
1.712PheGln: 1.712 ± 0.024
1.614PheArg: 1.614 ± 0.023
3.475PheSer: 3.475 ± 0.033
2.29PheThr: 2.29 ± 0.026
2.599PheVal: 2.599 ± 0.029
0.457PheTrp: 0.457 ± 0.011
1.15PheTyr: 1.15 ± 0.019
0.0PheXaa: 0.0 ± 0.0
Gly
3.255GlyAla: 3.255 ± 0.036
0.825GlyCys: 0.825 ± 0.015
2.569GlyAsp: 2.569 ± 0.027
2.395GlyGlu: 2.395 ± 0.028
2.361GlyPhe: 2.361 ± 0.031
3.342GlyGly: 3.342 ± 0.05
1.413GlyHis: 1.413 ± 0.022
3.681GlyIle: 3.681 ± 0.035
3.149GlyLys: 3.149 ± 0.034
4.847GlyLeu: 4.847 ± 0.033
1.413GlyMet: 1.413 ± 0.022
2.454GlyAsn: 2.454 ± 0.027
2.033GlyPro: 2.033 ± 0.031
2.071GlyGln: 2.071 ± 0.026
2.522GlyArg: 2.522 ± 0.032
5.119GlySer: 5.119 ± 0.05
3.217GlyThr: 3.217 ± 0.034
3.531GlyVal: 3.531 ± 0.034
0.653GlyTrp: 0.653 ± 0.014
1.751GlyTyr: 1.751 ± 0.025
0.0GlyXaa: 0.0 ± 0.0
His
1.867HisAla: 1.867 ± 0.026
0.436HisCys: 0.436 ± 0.011
1.406HisAsp: 1.406 ± 0.022
1.242HisGlu: 1.242 ± 0.019
1.045HisPhe: 1.045 ± 0.017
1.458HisGly: 1.458 ± 0.019
0.991HisHis: 0.991 ± 0.02
1.81HisIle: 1.81 ± 0.023
1.274HisLys: 1.274 ± 0.02
2.445HisLeu: 2.445 ± 0.029
0.627HisMet: 0.627 ± 0.012
1.107HisAsn: 1.107 ± 0.018
1.52HisPro: 1.52 ± 0.019
1.368HisGln: 1.368 ± 0.021
1.343HisArg: 1.343 ± 0.019
2.664HisSer: 2.664 ± 0.027
1.759HisThr: 1.759 ± 0.022
1.541HisVal: 1.541 ± 0.021
0.246HisTrp: 0.246 ± 0.008
0.794HisTyr: 0.794 ± 0.013
0.0HisXaa: 0.0 ± 0.0
Ile
4.483IleAla: 4.483 ± 0.033
1.016IleCys: 1.016 ± 0.017
3.936IleAsp: 3.936 ± 0.038
3.527IleGlu: 3.527 ± 0.034
2.297IlePhe: 2.297 ± 0.031
3.397IleGly: 3.397 ± 0.031
1.736IleHis: 1.736 ± 0.02
3.388IleIle: 3.388 ± 0.034
3.715IleLys: 3.715 ± 0.032
5.762IleLeu: 5.762 ± 0.041
1.401IleMet: 1.401 ± 0.021
2.761IleAsn: 2.761 ± 0.027
3.516IlePro: 3.516 ± 0.037
3.187IleGln: 3.187 ± 0.035
3.003IleArg: 3.003 ± 0.029
5.813IleSer: 5.813 ± 0.039
3.473IleThr: 3.473 ± 0.035
3.995IleVal: 3.995 ± 0.034
0.712IleTrp: 0.712 ± 0.015
1.772IleTyr: 1.772 ± 0.021
0.0IleXaa: 0.0 ± 0.0
Lys
3.694LysAla: 3.694 ± 0.036
0.816LysCys: 0.816 ± 0.018
2.951LysAsp: 2.951 ± 0.035
3.401LysGlu: 3.401 ± 0.035
1.869LysPhe: 1.869 ± 0.025
2.398LysGly: 2.398 ± 0.029
1.696LysHis: 1.696 ± 0.023
3.239LysIle: 3.239 ± 0.03
3.966LysLys: 3.966 ± 0.042
5.656LysLeu: 5.656 ± 0.037
1.39LysMet: 1.39 ± 0.017
2.59LysAsn: 2.59 ± 0.029
2.954LysPro: 2.954 ± 0.035
2.849LysGln: 2.849 ± 0.03
3.347LysArg: 3.347 ± 0.034
5.226LysSer: 5.226 ± 0.046
3.696LysThr: 3.696 ± 0.035
3.017LysVal: 3.017 ± 0.033
0.637LysTrp: 0.637 ± 0.012
1.881LysTyr: 1.881 ± 0.023
0.0LysXaa: 0.0 ± 0.0
Leu
6.973LeuAla: 6.973 ± 0.044
1.465LeuCys: 1.465 ± 0.022
5.907LeuAsp: 5.907 ± 0.038
5.832LeuGlu: 5.832 ± 0.049
3.875LeuPhe: 3.875 ± 0.036
4.849LeuGly: 4.849 ± 0.04
2.464LeuHis: 2.464 ± 0.027
5.029LeuIle: 5.029 ± 0.043
5.672LeuLys: 5.672 ± 0.047
8.653LeuLeu: 8.653 ± 0.069
2.067LeuMet: 2.067 ± 0.026
4.153LeuAsn: 4.153 ± 0.035
4.707LeuPro: 4.707 ± 0.044
4.471LeuGln: 4.471 ± 0.042
4.23LeuArg: 4.23 ± 0.041
8.36LeuSer: 8.36 ± 0.054
5.081LeuThr: 5.081 ± 0.04
5.958LeuVal: 5.958 ± 0.038
0.974LeuTrp: 0.974 ± 0.015
2.69LeuTyr: 2.69 ± 0.031
0.0LeuXaa: 0.0 ± 0.0
Met
1.889MetAla: 1.889 ± 0.024
0.332MetCys: 0.332 ± 0.011
1.684MetAsp: 1.684 ± 0.021
1.329MetGlu: 1.329 ± 0.017
0.983MetPhe: 0.983 ± 0.016
1.277MetGly: 1.277 ± 0.025
0.735MetHis: 0.735 ± 0.016
1.427MetIle: 1.427 ± 0.022
1.202MetLys: 1.202 ± 0.018
2.286MetLeu: 2.286 ± 0.023
0.672MetMet: 0.672 ± 0.016
1.104MetAsn: 1.104 ± 0.018
1.223MetPro: 1.223 ± 0.023
1.154MetGln: 1.154 ± 0.018
1.136MetArg: 1.136 ± 0.017
2.156MetSer: 2.156 ± 0.027
1.534MetThr: 1.534 ± 0.02
1.408MetVal: 1.408 ± 0.018
0.232MetTrp: 0.232 ± 0.009
0.767MetTyr: 0.767 ± 0.014
0.0MetXaa: 0.0 ± 0.0
Asn
3.323AsnAla: 3.323 ± 0.032
0.56AsnCys: 0.56 ± 0.013
2.6AsnAsp: 2.6 ± 0.026
2.394AsnGlu: 2.394 ± 0.03
1.41AsnPhe: 1.41 ± 0.021
2.778AsnGly: 2.778 ± 0.028
1.236AsnHis: 1.236 ± 0.018
3.127AsnIle: 3.127 ± 0.032
2.123AsnLys: 2.123 ± 0.023
4.019AsnLeu: 4.019 ± 0.033
1.165AsnMet: 1.165 ± 0.017
2.033AsnAsn: 2.033 ± 0.027
2.685AsnPro: 2.685 ± 0.033
2.224AsnGln: 2.224 ± 0.029
2.091AsnArg: 2.091 ± 0.024
4.13AsnSer: 4.13 ± 0.038
3.321AsnThr: 3.321 ± 0.033
2.643AsnVal: 2.643 ± 0.028
0.432AsnTrp: 0.432 ± 0.011
1.217AsnTyr: 1.217 ± 0.02
0.0AsnXaa: 0.0 ± 0.0
Pro
3.348ProAla: 3.348 ± 0.044
0.595ProCys: 0.595 ± 0.017
2.55ProAsp: 2.55 ± 0.028
2.635ProGlu: 2.635 ± 0.028
1.996ProPhe: 1.996 ± 0.024
2.294ProGly: 2.294 ± 0.034
1.188ProHis: 1.188 ± 0.023
3.269ProIle: 3.269 ± 0.034
2.668ProLys: 2.668 ± 0.03
4.319ProLeu: 4.319 ± 0.041
1.032ProMet: 1.032 ± 0.022
2.435ProAsn: 2.435 ± 0.027
2.908ProPro: 2.908 ± 0.07
1.994ProGln: 1.994 ± 0.032
1.87ProArg: 1.87 ± 0.024
5.312ProSer: 5.312 ± 0.051
3.729ProThr: 3.729 ± 0.035
3.32ProVal: 3.32 ± 0.041
0.426ProTrp: 0.426 ± 0.01
1.305ProTyr: 1.305 ± 0.02
0.0ProXaa: 0.0 ± 0.0
Gln
2.904GlnAla: 2.904 ± 0.037
0.599GlnCys: 0.599 ± 0.014
2.322GlnAsp: 2.322 ± 0.025
2.381GlnGlu: 2.381 ± 0.031
1.694GlnPhe: 1.694 ± 0.024
1.852GlnGly: 1.852 ± 0.025
1.444GlnHis: 1.444 ± 0.021
2.661GlnIle: 2.661 ± 0.031
2.571GlnLys: 2.571 ± 0.029
4.561GlnLeu: 4.561 ± 0.041
1.109GlnMet: 1.109 ± 0.018
2.012GlnAsn: 2.012 ± 0.025
2.504GlnPro: 2.504 ± 0.036
3.191GlnGln: 3.191 ± 0.061
2.294GlnArg: 2.294 ± 0.024
4.537GlnSer: 4.537 ± 0.034
2.897GlnThr: 2.897 ± 0.032
2.524GlnVal: 2.524 ± 0.024
0.476GlnTrp: 0.476 ± 0.011
1.383GlnTyr: 1.383 ± 0.019
0.0GlnXaa: 0.0 ± 0.0
Arg
2.842ArgAla: 2.842 ± 0.032
0.658ArgCys: 0.658 ± 0.016
2.416ArgAsp: 2.416 ± 0.031
2.406ArgGlu: 2.406 ± 0.028
2.077ArgPhe: 2.077 ± 0.023
2.212ArgGly: 2.212 ± 0.029
1.36ArgHis: 1.36 ± 0.019
3.188ArgIle: 3.188 ± 0.028
3.041ArgLys: 3.041 ± 0.032
4.983ArgLeu: 4.983 ± 0.041
1.21ArgMet: 1.21 ± 0.017
2.134ArgAsn: 2.134 ± 0.026
2.106ArgPro: 2.106 ± 0.026
2.268ArgGln: 2.268 ± 0.027
2.91ArgArg: 2.91 ± 0.035
4.103ArgSer: 4.103 ± 0.037
2.55ArgThr: 2.55 ± 0.027
2.855ArgVal: 2.855 ± 0.027
0.473ArgTrp: 0.473 ± 0.012
1.47ArgTyr: 1.47 ± 0.021
0.0ArgXaa: 0.0 ± 0.0
Ser
6.366SerAla: 6.366 ± 0.05
1.201SerCys: 1.201 ± 0.021
5.166SerAsp: 5.166 ± 0.043
4.284SerGlu: 4.284 ± 0.037
3.5SerPhe: 3.5 ± 0.035
5.035SerGly: 5.035 ± 0.041
2.443SerHis: 2.443 ± 0.029
6.273SerIle: 6.273 ± 0.039
5.709SerLys: 5.709 ± 0.046
8.249SerLeu: 8.249 ± 0.054
2.191SerMet: 2.191 ± 0.03
4.981SerAsn: 4.981 ± 0.041
4.489SerPro: 4.489 ± 0.048
4.004SerGln: 4.004 ± 0.043
4.331SerArg: 4.331 ± 0.036
9.997SerSer: 9.997 ± 0.083
7.474SerThr: 7.474 ± 0.06
5.513SerVal: 5.513 ± 0.035
0.83SerTrp: 0.83 ± 0.017
2.203SerTyr: 2.203 ± 0.028
0.0SerXaa: 0.0 ± 0.0
Thr
4.903ThrAla: 4.903 ± 0.04
0.931ThrCys: 0.931 ± 0.017
3.597ThrAsp: 3.597 ± 0.036
3.074ThrGlu: 3.074 ± 0.033
2.458ThrPhe: 2.458 ± 0.03
3.507ThrGly: 3.507 ± 0.037
1.746ThrHis: 1.746 ± 0.02
4.041ThrIle: 4.041 ± 0.034
3.289ThrLys: 3.289 ± 0.03
6.081ThrLeu: 6.081 ± 0.04
1.448ThrMet: 1.448 ± 0.02
2.898ThrAsn: 2.898 ± 0.033
3.822ThrPro: 3.822 ± 0.045
2.537ThrGln: 2.537 ± 0.03
2.744ThrArg: 2.744 ± 0.027
6.114ThrSer: 6.114 ± 0.048
5.031ThrThr: 5.031 ± 0.068
4.186ThrVal: 4.186 ± 0.036
0.581ThrTrp: 0.581 ± 0.014
1.576ThrTyr: 1.576 ± 0.018
0.0ThrXaa: 0.0 ± 0.0
Val
4.458ValAla: 4.458 ± 0.036
1.066ValCys: 1.066 ± 0.018
3.929ValAsp: 3.929 ± 0.033
3.471ValGlu: 3.471 ± 0.029
2.683ValPhe: 2.683 ± 0.027
3.267ValGly: 3.267 ± 0.035
1.528ValHis: 1.528 ± 0.018
3.432ValIle: 3.432 ± 0.029
3.308ValLys: 3.308 ± 0.031
5.716ValLeu: 5.716 ± 0.046
1.465ValMet: 1.465 ± 0.019
2.577ValAsn: 2.577 ± 0.028
2.846ValPro: 2.846 ± 0.034
2.63ValGln: 2.63 ± 0.03
2.682ValArg: 2.682 ± 0.029
5.653ValSer: 5.653 ± 0.036
3.416ValThr: 3.416 ± 0.03
4.267ValVal: 4.267 ± 0.04
0.703ValTrp: 0.703 ± 0.014
1.97ValTyr: 1.97 ± 0.027
0.0ValXaa: 0.0 ± 0.0
Trp
0.62TrpAla: 0.62 ± 0.014
0.174TrpCys: 0.174 ± 0.008
0.655TrpAsp: 0.655 ± 0.016
0.536TrpGlu: 0.536 ± 0.012
0.432TrpPhe: 0.432 ± 0.01
0.48TrpGly: 0.48 ± 0.012
0.274TrpHis: 0.274 ± 0.009
0.765TrpIle: 0.765 ± 0.015
0.73TrpLys: 0.73 ± 0.013
0.924TrpLeu: 0.924 ± 0.015
0.324TrpMet: 0.324 ± 0.009
0.589TrpAsn: 0.589 ± 0.013
0.358TrpPro: 0.358 ± 0.011
0.42TrpGln: 0.42 ± 0.012
0.563TrpArg: 0.563 ± 0.014
0.901TrpSer: 0.901 ± 0.014
0.704TrpThr: 0.704 ± 0.015
0.622TrpVal: 0.622 ± 0.014
0.176TrpTrp: 0.176 ± 0.006
0.305TrpTyr: 0.305 ± 0.009
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.854TyrAla: 1.854 ± 0.024
0.515TyrCys: 0.515 ± 0.013
1.692TyrAsp: 1.692 ± 0.023
1.505TyrGlu: 1.505 ± 0.02
1.329TyrPhe: 1.329 ± 0.019
1.786TyrGly: 1.786 ± 0.023
0.775TyrHis: 0.775 ± 0.017
1.919TyrIle: 1.919 ± 0.023
1.501TyrLys: 1.501 ± 0.018
2.707TyrLeu: 2.707 ± 0.033
0.762TyrMet: 0.762 ± 0.016
1.436TyrAsn: 1.436 ± 0.02
1.357TyrPro: 1.357 ± 0.018
1.358TyrGln: 1.358 ± 0.021
1.523TyrArg: 1.523 ± 0.022
2.454TyrSer: 2.454 ± 0.029
1.804TyrThr: 1.804 ± 0.025
1.522TyrVal: 1.522 ± 0.021
0.355TyrTrp: 0.355 ± 0.01
1.029TyrTyr: 1.029 ± 0.018
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 8610 proteins (3887913 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski