Amino acid dipepetide frequency for Fomitopsis pinicola (strain FP-58527) (Brown rot fungus)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	10.103AlaAla: 10.103 ± 0.063	1.218AlaCys: 1.218 ± 0.016	4.786AlaAsp: 4.786 ± 0.033	5.48AlaGlu: 5.48 ± 0.041	3.32AlaPhe: 3.32 ± 0.028	5.982AlaGly: 5.982 ± 0.039	2.412AlaHis: 2.412 ± 0.019	4.105AlaIle: 4.105 ± 0.025	3.863AlaLys: 3.863 ± 0.034	9.266AlaLeu: 9.266 ± 0.049	2.077AlaMet: 2.077 ± 0.02	2.76AlaAsn: 2.76 ± 0.022	5.948AlaPro: 5.948 ± 0.043	3.769AlaGln: 3.769 ± 0.027	6.43AlaArg: 6.43 ± 0.04	8.104AlaSer: 8.104 ± 0.049	5.655AlaThr: 5.655 ± 0.03	6.14AlaVal: 6.14 ± 0.037	1.345AlaTrp: 1.345 ± 0.017	2.449AlaTyr: 2.449 ± 0.021	0.0AlaXaa: 0.0 ± 0.0
Cys	1.143CysAla: 1.143 ± 0.015	0.259CysCys: 0.259 ± 0.007	0.688CysAsp: 0.688 ± 0.012	0.631CysGlu: 0.631 ± 0.013	0.47CysPhe: 0.47 ± 0.01	0.974CysGly: 0.974 ± 0.015	0.342CysHis: 0.342 ± 0.008	0.661CysIle: 0.661 ± 0.01	0.521CysLys: 0.521 ± 0.013	1.258CysLeu: 1.258 ± 0.019	0.313CysMet: 0.313 ± 0.007	0.408CysAsn: 0.408 ± 0.009	0.784CysPro: 0.784 ± 0.013	0.426CysGln: 0.426 ± 0.01	0.836CysArg: 0.836 ± 0.011	0.936CysSer: 0.936 ± 0.015	0.797CysThr: 0.797 ± 0.011	0.869CysVal: 0.869 ± 0.013	0.207CysTrp: 0.207 ± 0.007	0.354CysTyr: 0.354 ± 0.008	0.0CysXaa: 0.0 ± 0.0
Asp	5.691AspAla: 5.691 ± 0.031	0.65AspCys: 0.65 ± 0.014	4.363AspAsp: 4.363 ± 0.038	4.601AspGlu: 4.601 ± 0.037	2.059AspPhe: 2.059 ± 0.02	4.137AspGly: 4.137 ± 0.031	1.231AspHis: 1.231 ± 0.016	2.865AspIle: 2.865 ± 0.024	2.059AspLys: 2.059 ± 0.021	4.903AspLeu: 4.903 ± 0.034	1.281AspMet: 1.281 ± 0.014	1.575AspAsn: 1.575 ± 0.016	3.493AspPro: 3.493 ± 0.022	1.532AspGln: 1.532 ± 0.017	3.009AspArg: 3.009 ± 0.027	3.802AspSer: 3.802 ± 0.03	3.023AspThr: 3.023 ± 0.025	4.395AspVal: 4.395 ± 0.028	0.946AspTrp: 0.946 ± 0.014	1.506AspTyr: 1.506 ± 0.017	0.0AspXaa: 0.0 ± 0.0
Glu	5.627GluAla: 5.627 ± 0.042	0.662GluCys: 0.662 ± 0.013	4.352GluAsp: 4.352 ± 0.032	5.498GluGlu: 5.498 ± 0.048	1.728GluPhe: 1.728 ± 0.017	3.893GluGly: 3.893 ± 0.03	1.625GluHis: 1.625 ± 0.016	2.504GluIle: 2.504 ± 0.022	2.89GluLys: 2.89 ± 0.028	5.545GluLeu: 5.545 ± 0.036	1.328GluMet: 1.328 ± 0.012	1.684GluAsn: 1.684 ± 0.018	3.002GluPro: 3.002 ± 0.026	2.394GluGln: 2.394 ± 0.023	4.375GluArg: 4.375 ± 0.037	3.765GluSer: 3.765 ± 0.028	3.039GluThr: 3.039 ± 0.025	3.873GluVal: 3.873 ± 0.027	0.964GluTrp: 0.964 ± 0.014	1.593GluTyr: 1.593 ± 0.019	0.0GluXaa: 0.0 ± 0.0
Phe	3.195PheAla: 3.195 ± 0.025	0.524PheCys: 0.524 ± 0.01	2.189PheAsp: 2.189 ± 0.022	1.938PheGlu: 1.938 ± 0.019	1.343PhePhe: 1.343 ± 0.017	2.544PheGly: 2.544 ± 0.028	0.886PheHis: 0.886 ± 0.015	1.552PheIle: 1.552 ± 0.021	1.331PheLys: 1.331 ± 0.016	3.269PheLeu: 3.269 ± 0.027	0.752PheMet: 0.752 ± 0.011	1.172PheAsn: 1.172 ± 0.015	1.943PhePro: 1.943 ± 0.021	1.095PheGln: 1.095 ± 0.014	1.975PheArg: 1.975 ± 0.02	2.737PheSer: 2.737 ± 0.025	2.035PheThr: 2.035 ± 0.02	2.517PheVal: 2.517 ± 0.025	0.587PheTrp: 0.587 ± 0.011	1.012PheTyr: 1.012 ± 0.013	0.0PheXaa: 0.0 ± 0.0
Gly	5.759GlyAla: 5.759 ± 0.035	0.891GlyCys: 0.891 ± 0.015	3.634GlyAsp: 3.634 ± 0.028	3.687GlyGlu: 3.687 ± 0.03	2.419GlyPhe: 2.419 ± 0.022	5.441GlyGly: 5.441 ± 0.059	1.791GlyHis: 1.791 ± 0.02	3.072GlyIle: 3.072 ± 0.027	3.177GlyLys: 3.177 ± 0.027	5.674GlyLeu: 5.674 ± 0.036	1.543GlyMet: 1.543 ± 0.022	2.048GlyAsn: 2.048 ± 0.02	3.526GlyPro: 3.526 ± 0.03	2.322GlyGln: 2.322 ± 0.026	4.353GlyArg: 4.353 ± 0.031	5.424GlySer: 5.424 ± 0.041	4.093GlyThr: 4.093 ± 0.032	4.434GlyVal: 4.434 ± 0.033	1.146GlyTrp: 1.146 ± 0.015	1.899GlyTyr: 1.899 ± 0.021	0.0GlyXaa: 0.0 ± 0.0
His	2.532HisAla: 2.532 ± 0.02	0.38HisCys: 0.38 ± 0.008	1.415HisAsp: 1.415 ± 0.017	1.377HisGlu: 1.377 ± 0.017	0.963HisPhe: 0.963 ± 0.014	1.779HisGly: 1.779 ± 0.021	0.835HisHis: 0.835 ± 0.017	1.309HisIle: 1.309 ± 0.016	0.919HisLys: 0.919 ± 0.013	2.524HisLeu: 2.524 ± 0.024	0.53HisMet: 0.53 ± 0.009	0.776HisAsn: 0.776 ± 0.012	1.954HisPro: 1.954 ± 0.022	0.822HisGln: 0.822 ± 0.013	1.728HisArg: 1.728 ± 0.021	1.951HisSer: 1.951 ± 0.022	1.564HisThr: 1.564 ± 0.016	1.719HisVal: 1.719 ± 0.019	0.375HisTrp: 0.375 ± 0.009	0.716HisTyr: 0.716 ± 0.011	0.0HisXaa: 0.0 ± 0.0
Ile	4.186IleAla: 4.186 ± 0.028	0.683IleCys: 0.683 ± 0.013	2.569IleAsp: 2.569 ± 0.021	2.481IleGlu: 2.481 ± 0.024	1.588IlePhe: 1.588 ± 0.02	2.777IleGly: 2.777 ± 0.026	1.157IleHis: 1.157 ± 0.014	2.121IleIle: 2.121 ± 0.022	1.707IleLys: 1.707 ± 0.018	4.162IleLeu: 4.162 ± 0.03	0.906IleMet: 0.906 ± 0.013	1.345IleAsn: 1.345 ± 0.019	3.021IlePro: 3.021 ± 0.024	1.557IleGln: 1.557 ± 0.018	2.751IleArg: 2.751 ± 0.024	3.224IleSer: 3.224 ± 0.028	2.527IleThr: 2.527 ± 0.022	3.2IleVal: 3.2 ± 0.032	0.702IleTrp: 0.702 ± 0.013	1.219IleTyr: 1.219 ± 0.016	0.0IleXaa: 0.0 ± 0.0
Lys	4.194LysAla: 4.194 ± 0.035	0.463LysCys: 0.463 ± 0.01	2.352LysAsp: 2.352 ± 0.026	2.86LysGlu: 2.86 ± 0.026	1.167LysPhe: 1.167 ± 0.015	2.679LysGly: 2.679 ± 0.027	1.12LysHis: 1.12 ± 0.014	1.706LysIle: 1.706 ± 0.019	2.62LysLys: 2.62 ± 0.037	3.676LysLeu: 3.676 ± 0.027	0.84LysMet: 0.84 ± 0.013	1.179LysAsn: 1.179 ± 0.016	2.445LysPro: 2.445 ± 0.024	1.575LysGln: 1.575 ± 0.018	3.351LysArg: 3.351 ± 0.028	2.681LysSer: 2.681 ± 0.024	2.383LysThr: 2.383 ± 0.022	2.575LysVal: 2.575 ± 0.022	0.643LysTrp: 0.643 ± 0.011	1.175LysTyr: 1.175 ± 0.013	0.0LysXaa: 0.0 ± 0.0
Leu	8.935LeuAla: 8.935 ± 0.041	1.358LeuCys: 1.358 ± 0.018	5.305LeuAsp: 5.305 ± 0.037	5.396LeuGlu: 5.396 ± 0.039	3.238LeuPhe: 3.238 ± 0.025	5.738LeuGly: 5.738 ± 0.037	2.604LeuHis: 2.604 ± 0.025	3.49LeuIle: 3.49 ± 0.031	3.672LeuLys: 3.672 ± 0.028	8.666LeuLeu: 8.666 ± 0.059	1.717LeuMet: 1.717 ± 0.019	2.856LeuAsn: 2.856 ± 0.025	6.245LeuPro: 6.245 ± 0.039	3.706LeuGln: 3.706 ± 0.03	6.703LeuArg: 6.703 ± 0.038	7.532LeuSer: 7.532 ± 0.04	5.211LeuThr: 5.211 ± 0.03	6.027LeuVal: 6.027 ± 0.042	1.297LeuTrp: 1.297 ± 0.015	2.461LeuTyr: 2.461 ± 0.02	0.0LeuXaa: 0.0 ± 0.0
Met	1.931MetAla: 1.931 ± 0.017	0.27MetCys: 0.27 ± 0.007	1.175MetAsp: 1.175 ± 0.014	1.154MetGlu: 1.154 ± 0.015	0.733MetPhe: 0.733 ± 0.011	1.3MetGly: 1.3 ± 0.019	0.582MetHis: 0.582 ± 0.011	0.856MetIle: 0.856 ± 0.014	0.899MetLys: 0.899 ± 0.012	2.014MetLeu: 2.014 ± 0.017	0.502MetMet: 0.502 ± 0.011	0.692MetAsn: 0.692 ± 0.011	1.413MetPro: 1.413 ± 0.019	0.883MetGln: 0.883 ± 0.014	1.441MetArg: 1.441 ± 0.017	1.971MetSer: 1.971 ± 0.018	1.216MetThr: 1.216 ± 0.014	1.207MetVal: 1.207 ± 0.015	0.302MetTrp: 0.302 ± 0.008	0.565MetTyr: 0.565 ± 0.011	0.0MetXaa: 0.0 ± 0.0
Asn	3.065AsnAla: 3.065 ± 0.025	0.364AsnCys: 0.364 ± 0.008	1.583AsnAsp: 1.583 ± 0.016	1.629AsnGlu: 1.629 ± 0.017	1.044AsnPhe: 1.044 ± 0.016	2.416AsnGly: 2.416 ± 0.025	0.729AsnHis: 0.729 ± 0.011	1.643AsnIle: 1.643 ± 0.017	1.169AsnLys: 1.169 ± 0.015	2.762AsnLeu: 2.762 ± 0.021	0.72AsnMet: 0.72 ± 0.012	1.06AsnAsn: 1.06 ± 0.016	2.045AsnPro: 2.045 ± 0.021	0.932AsnGln: 0.932 ± 0.014	1.61AsnArg: 1.61 ± 0.017	2.051AsnSer: 2.051 ± 0.023	1.866AsnThr: 1.866 ± 0.02	2.309AsnVal: 2.309 ± 0.022	0.488AsnTrp: 0.488 ± 0.01	0.852AsnTyr: 0.852 ± 0.014	0.0AsnXaa: 0.0 ± 0.0
Pro	6.308ProAla: 6.308 ± 0.047	0.564ProCys: 0.564 ± 0.013	3.47ProAsp: 3.47 ± 0.025	3.878ProGlu: 3.878 ± 0.029	2.104ProPhe: 2.104 ± 0.02	4.076ProGly: 4.076 ± 0.031	1.646ProHis: 1.646 ± 0.018	2.472ProIle: 2.472 ± 0.022	2.281ProLys: 2.281 ± 0.02	5.389ProLeu: 5.389 ± 0.034	1.154ProMet: 1.154 ± 0.014	1.951ProAsn: 1.951 ± 0.019	6.484ProPro: 6.484 ± 0.075	2.441ProGln: 2.441 ± 0.029	4.045ProArg: 4.045 ± 0.029	6.841ProSer: 6.841 ± 0.054	4.469ProThr: 4.469 ± 0.037	4.045ProVal: 4.045 ± 0.033	0.755ProTrp: 0.755 ± 0.012	1.645ProTyr: 1.645 ± 0.02	0.0ProXaa: 0.0 ± 0.0
Gln	3.556GlnAla: 3.556 ± 0.029	0.49GlnCys: 0.49 ± 0.01	1.92GlnAsp: 1.92 ± 0.018	2.222GlnGlu: 2.222 ± 0.023	1.158GlnPhe: 1.158 ± 0.016	2.258GlnGly: 2.258 ± 0.022	1.063GlnHis: 1.063 ± 0.016	1.491GlnIle: 1.491 ± 0.019	1.5GlnLys: 1.5 ± 0.019	3.532GlnLeu: 3.532 ± 0.026	0.782GlnMet: 0.782 ± 0.012	1.149GlnAsn: 1.149 ± 0.013	2.413GlnPro: 2.413 ± 0.032	1.843GlnGln: 1.843 ± 0.033	2.637GlnArg: 2.637 ± 0.028	2.722GlnSer: 2.722 ± 0.024	2.137GlnThr: 2.137 ± 0.021	2.172GlnVal: 2.172 ± 0.022	0.586GlnTrp: 0.586 ± 0.011	1.128GlnTyr: 1.128 ± 0.014	0.0GlnXaa: 0.0 ± 0.0
Arg	6.198ArgAla: 6.198 ± 0.038	0.87ArgCys: 0.87 ± 0.013	3.573ArgAsp: 3.573 ± 0.029	4.211ArgGlu: 4.211 ± 0.038	2.162ArgPhe: 2.162 ± 0.021	4.014ArgGly: 4.014 ± 0.035	1.768ArgHis: 1.768 ± 0.02	2.938ArgIle: 2.938 ± 0.023	3.345ArgLys: 3.345 ± 0.028	6.055ArgLeu: 6.055 ± 0.035	1.509ArgMet: 1.509 ± 0.019	1.974ArgAsn: 1.974 ± 0.018	4.062ArgPro: 4.062 ± 0.03	2.463ArgGln: 2.463 ± 0.023	5.806ArgArg: 5.806 ± 0.043	5.049ArgSer: 5.049 ± 0.036	3.898ArgThr: 3.898 ± 0.027	4.111ArgVal: 4.111 ± 0.029	1.074ArgTrp: 1.074 ± 0.015	1.703ArgTyr: 1.703 ± 0.018	0.0ArgXaa: 0.0 ± 0.0
Ser	7.543SerAla: 7.543 ± 0.05	0.853SerCys: 0.853 ± 0.014	4.204SerAsp: 4.204 ± 0.029	4.0SerGlu: 4.0 ± 0.032	2.681SerPhe: 2.681 ± 0.026	5.485SerGly: 5.485 ± 0.038	1.91SerHis: 1.91 ± 0.02	3.408SerIle: 3.408 ± 0.028	3.027SerLys: 3.027 ± 0.025	7.291SerLeu: 7.291 ± 0.043	1.689SerMet: 1.689 ± 0.016	2.313SerAsn: 2.313 ± 0.022	6.003SerPro: 6.003 ± 0.059	2.881SerGln: 2.881 ± 0.026	5.1SerArg: 5.1 ± 0.035	8.596SerSer: 8.596 ± 0.073	5.529SerThr: 5.529 ± 0.04	5.035SerVal: 5.035 ± 0.034	1.037SerTrp: 1.037 ± 0.017	1.927SerTyr: 1.927 ± 0.02	0.0SerXaa: 0.0 ± 0.0
Thr	5.531ThrAla: 5.531 ± 0.033	0.78ThrCys: 0.78 ± 0.014	2.836ThrAsp: 2.836 ± 0.024	2.943ThrGlu: 2.943 ± 0.024	2.278ThrPhe: 2.278 ± 0.02	3.89ThrGly: 3.89 ± 0.031	1.551ThrHis: 1.551 ± 0.016	2.767ThrIle: 2.767 ± 0.025	2.201ThrLys: 2.201 ± 0.024	5.822ThrLeu: 5.822 ± 0.037	1.154ThrMet: 1.154 ± 0.013	1.773ThrAsn: 1.773 ± 0.019	4.644ThrPro: 4.644 ± 0.032	2.063ThrGln: 2.063 ± 0.021	3.605ThrArg: 3.605 ± 0.026	5.342ThrSer: 5.342 ± 0.04	4.011ThrThr: 4.011 ± 0.03	3.996ThrVal: 3.996 ± 0.027	0.831ThrTrp: 0.831 ± 0.013	1.65ThrTyr: 1.65 ± 0.018	0.0ThrXaa: 0.0 ± 0.0
Val	6.012ValAla: 6.012 ± 0.035	0.953ValCys: 0.953 ± 0.013	4.055ValAsp: 4.055 ± 0.028	3.986ValGlu: 3.986 ± 0.03	2.572ValPhe: 2.572 ± 0.026	4.08ValGly: 4.08 ± 0.034	1.776ValHis: 1.776 ± 0.019	2.935ValIle: 2.935 ± 0.026	2.747ValLys: 2.747 ± 0.024	6.385ValLeu: 6.385 ± 0.038	1.34ValMet: 1.34 ± 0.016	2.07ValAsn: 2.07 ± 0.021	4.328ValPro: 4.328 ± 0.032	2.556ValGln: 2.556 ± 0.02	4.209ValArg: 4.209 ± 0.031	4.819ValSer: 4.819 ± 0.033	3.663ValThr: 3.663 ± 0.025	4.922ValVal: 4.922 ± 0.034	1.025ValTrp: 1.025 ± 0.015	1.906ValTyr: 1.906 ± 0.019	0.0ValXaa: 0.0 ± 0.0
Trp	1.247TrpAla: 1.247 ± 0.017	0.221TrpCys: 0.221 ± 0.007	0.909TrpAsp: 0.909 ± 0.016	0.877TrpGlu: 0.877 ± 0.013	0.538TrpPhe: 0.538 ± 0.01	0.902TrpGly: 0.902 ± 0.015	0.413TrpHis: 0.413 ± 0.008	0.687TrpIle: 0.687 ± 0.012	0.759TrpLys: 0.759 ± 0.014	1.416TrpLeu: 1.416 ± 0.018	0.377TrpMet: 0.377 ± 0.009	0.568TrpAsn: 0.568 ± 0.011	0.691TrpPro: 0.691 ± 0.012	0.585TrpGln: 0.585 ± 0.01	1.153TrpArg: 1.153 ± 0.016	1.075TrpSer: 1.075 ± 0.014	0.917TrpThr: 0.917 ± 0.014	0.923TrpVal: 0.923 ± 0.016	0.286TrpTrp: 0.286 ± 0.008	0.463TrpTyr: 0.463 ± 0.009	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.457TyrAla: 2.457 ± 0.021	0.423TyrCys: 0.423 ± 0.008	1.744TyrAsp: 1.744 ± 0.019	1.492TyrGlu: 1.492 ± 0.017	1.03TyrPhe: 1.03 ± 0.015	1.97TyrGly: 1.97 ± 0.019	0.727TyrHis: 0.727 ± 0.012	1.299TyrIle: 1.299 ± 0.018	0.995TyrLys: 0.995 ± 0.012	2.546TyrLeu: 2.546 ± 0.022	0.594TyrMet: 0.594 ± 0.009	0.984TyrAsn: 0.984 ± 0.013	1.571TyrPro: 1.571 ± 0.02	0.916TyrGln: 0.916 ± 0.014	1.667TyrArg: 1.667 ± 0.015	1.89TyrSer: 1.89 ± 0.02	1.637TyrThr: 1.637 ± 0.019	1.866TyrVal: 1.866 ± 0.021	0.413TyrTrp: 0.413 ± 0.008	0.88TyrTyr: 0.88 ± 0.015	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 13806 proteins (5596684 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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