Amino acid dipepetide frequency for Wenzhou shrimp virus 7

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.982AlaAla: 4.982 ± 0.166
1.993AlaCys: 1.993 ± 0.989
2.989AlaAsp: 2.989 ± 0.627
1.993AlaGlu: 1.993 ± 0.066
1.328AlaPhe: 1.328 ± 0.132
5.646AlaGly: 5.646 ± 0.892
1.993AlaHis: 1.993 ± 0.989
3.985AlaIle: 3.985 ± 1.716
4.65AlaLys: 4.65 ± 0.859
5.646AlaLeu: 5.646 ± 1.219
0.996AlaMet: 0.996 ± 0.194
2.989AlaAsn: 2.989 ± 1.155
2.989AlaPro: 2.989 ± 0.627
3.321AlaGln: 3.321 ± 0.463
2.325AlaArg: 2.325 ± 1.154
5.978AlaSer: 5.978 ± 0.328
3.321AlaThr: 3.321 ± 0.065
2.989AlaVal: 2.989 ± 0.1
0.664AlaTrp: 0.664 ± 0.198
1.661AlaTyr: 1.661 ± 0.231
0.0AlaXaa: 0.0 ± 0.0
Cys
0.332CysAla: 0.332 ± 0.165
0.996CysCys: 0.996 ± 0.494
1.661CysAsp: 1.661 ± 0.296
1.661CysGlu: 1.661 ± 0.824
1.328CysPhe: 1.328 ± 0.659
0.996CysGly: 0.996 ± 0.494
0.332CysHis: 0.332 ± 0.165
0.664CysIle: 0.664 ± 0.33
2.325CysLys: 2.325 ± 1.154
1.993CysLeu: 1.993 ± 0.989
0.664CysMet: 0.664 ± 0.33
1.328CysAsn: 1.328 ± 0.659
0.996CysPro: 0.996 ± 0.033
0.0CysGln: 0.0 ± 0.0
2.325CysArg: 2.325 ± 0.626
2.325CysSer: 2.325 ± 1.154
1.328CysThr: 1.328 ± 0.659
3.653CysVal: 3.653 ± 1.813
0.0CysTrp: 0.0 ± 0.0
0.332CysTyr: 0.332 ± 0.165
0.0CysXaa: 0.0 ± 0.0
Asp
3.653AspAla: 3.653 ± 1.285
1.328AspCys: 1.328 ± 0.659
3.985AspAsp: 3.985 ± 0.133
4.65AspGlu: 4.65 ± 1.252
1.993AspPhe: 1.993 ± 0.989
2.657AspGly: 2.657 ± 0.263
1.661AspHis: 1.661 ± 0.231
3.653AspIle: 3.653 ± 1.353
3.321AspLys: 3.321 ± 0.593
4.318AspLeu: 4.318 ± 0.496
1.328AspMet: 1.328 ± 0.659
3.653AspAsn: 3.653 ± 0.23
2.657AspPro: 2.657 ± 0.264
0.664AspGln: 0.664 ± 0.198
1.993AspArg: 1.993 ± 0.461
4.65AspSer: 4.65 ± 1.386
4.65AspThr: 4.65 ± 0.331
6.31AspVal: 6.31 ± 1.549
1.328AspTrp: 1.328 ± 0.659
3.321AspTyr: 3.321 ± 0.463
0.0AspXaa: 0.0 ± 0.0
Glu
2.989GluAla: 2.989 ± 0.428
0.332GluCys: 0.332 ± 0.165
1.661GluAsp: 1.661 ± 0.296
1.328GluGlu: 1.328 ± 0.659
2.325GluPhe: 2.325 ± 0.626
2.657GluGly: 2.657 ± 0.264
0.996GluHis: 0.996 ± 0.033
2.325GluIle: 2.325 ± 0.626
1.993GluLys: 1.993 ± 0.989
4.982GluLeu: 4.982 ± 0.166
0.664GluMet: 0.664 ± 0.198
3.321GluAsn: 3.321 ± 0.99
0.332GluPro: 0.332 ± 0.363
1.661GluGln: 1.661 ± 0.231
0.664GluArg: 0.664 ± 0.33
6.31GluSer: 6.31 ± 0.493
3.653GluThr: 3.653 ± 0.23
2.989GluVal: 2.989 ± 0.428
0.996GluTrp: 0.996 ± 0.033
3.321GluTyr: 3.321 ± 0.065
0.0GluXaa: 0.0 ± 0.0
Phe
2.325PheAla: 2.325 ± 0.626
2.325PheCys: 2.325 ± 1.154
2.325PheAsp: 2.325 ± 0.429
2.657PheGlu: 2.657 ± 0.264
1.328PhePhe: 1.328 ± 0.659
2.325PheGly: 2.325 ± 0.957
1.661PheHis: 1.661 ± 0.231
2.657PheIle: 2.657 ± 0.263
1.328PheLys: 1.328 ± 0.659
3.985PheLeu: 3.985 ± 0.395
1.328PheMet: 1.328 ± 0.659
2.657PheAsn: 2.657 ± 0.791
3.321PhePro: 3.321 ± 1.518
0.996PheGln: 0.996 ± 0.494
0.996PheArg: 0.996 ± 0.494
3.653PheSer: 3.653 ± 0.23
3.321PheThr: 3.321 ± 2.046
3.321PheVal: 3.321 ± 1.121
0.996PheTrp: 0.996 ± 0.033
0.664PheTyr: 0.664 ± 0.198
0.0PheXaa: 0.0 ± 0.0
Gly
3.985GlyAla: 3.985 ± 0.661
1.993GlyCys: 1.993 ± 0.461
4.982GlyAsp: 4.982 ± 1.221
1.661GlyGlu: 1.661 ± 1.287
3.985GlyPhe: 3.985 ± 1.188
1.993GlyGly: 1.993 ± 0.066
0.996GlyHis: 0.996 ± 0.033
2.657GlyIle: 2.657 ± 1.32
1.993GlyLys: 1.993 ± 0.989
5.314GlyLeu: 5.314 ± 1.054
0.332GlyMet: 0.332 ± 0.165
2.325GlyAsn: 2.325 ± 0.429
0.996GlyPro: 0.996 ± 1.089
0.664GlyGln: 0.664 ± 0.198
2.325GlyArg: 2.325 ± 0.098
5.314GlySer: 5.314 ± 1.057
4.318GlyThr: 4.318 ± 0.032
4.65GlyVal: 4.65 ± 0.197
0.332GlyTrp: 0.332 ± 0.165
1.993GlyTyr: 1.993 ± 0.461
0.0GlyXaa: 0.0 ± 0.0
His
1.328HisAla: 1.328 ± 0.396
0.996HisCys: 0.996 ± 0.494
0.996HisAsp: 0.996 ± 0.494
0.664HisGlu: 0.664 ± 0.33
0.664HisPhe: 0.664 ± 0.33
2.989HisGly: 2.989 ± 0.428
0.996HisHis: 0.996 ± 0.494
0.332HisIle: 0.332 ± 0.165
0.332HisLys: 0.332 ± 0.165
0.996HisLeu: 0.996 ± 0.033
0.664HisMet: 0.664 ± 0.33
0.996HisAsn: 0.996 ± 0.494
0.996HisPro: 0.996 ± 0.494
2.657HisGln: 2.657 ± 0.791
0.332HisArg: 0.332 ± 0.165
2.325HisSer: 2.325 ± 0.626
1.993HisThr: 1.993 ± 0.066
3.985HisVal: 3.985 ± 1.45
0.332HisTrp: 0.332 ± 0.165
1.328HisTyr: 1.328 ± 0.132
0.0HisXaa: 0.0 ± 0.0
Ile
4.982IleAla: 4.982 ± 0.166
0.0IleCys: 0.0 ± 0.0
3.985IleAsp: 3.985 ± 0.133
1.993IleGlu: 1.993 ± 0.594
1.993IlePhe: 1.993 ± 0.066
3.321IleGly: 3.321 ± 0.463
0.996IleHis: 0.996 ± 0.494
2.657IleIle: 2.657 ± 0.791
1.993IleLys: 1.993 ± 0.594
3.321IleLeu: 3.321 ± 1.518
0.996IleMet: 0.996 ± 0.033
2.657IleAsn: 2.657 ± 1.32
3.653IlePro: 3.653 ± 0.825
0.996IleGln: 0.996 ± 0.561
0.996IleArg: 0.996 ± 0.033
4.318IleSer: 4.318 ± 3.662
2.325IleThr: 2.325 ± 0.098
6.974IleVal: 6.974 ± 0.232
0.664IleTrp: 0.664 ± 0.33
1.328IleTyr: 1.328 ± 0.659
0.0IleXaa: 0.0 ± 0.0
Lys
2.989LysAla: 2.989 ± 0.956
2.325LysCys: 2.325 ± 1.154
2.989LysAsp: 2.989 ± 0.428
1.661LysGlu: 1.661 ± 0.824
1.661LysPhe: 1.661 ± 0.824
2.989LysGly: 2.989 ± 1.155
0.332LysHis: 0.332 ± 0.165
3.321LysIle: 3.321 ± 0.593
1.661LysLys: 1.661 ± 0.824
3.653LysLeu: 3.653 ± 0.298
0.332LysMet: 0.332 ± 0.363
4.318LysAsn: 4.318 ± 1.087
2.657LysPro: 2.657 ± 0.263
2.657LysGln: 2.657 ± 0.791
1.661LysArg: 1.661 ± 0.824
3.321LysSer: 3.321 ± 1.648
1.993LysThr: 1.993 ± 0.066
4.318LysVal: 4.318 ± 1.087
0.332LysTrp: 0.332 ± 0.363
0.996LysTyr: 0.996 ± 0.494
0.0LysXaa: 0.0 ± 0.0
Leu
8.303LeuAla: 8.303 ± 2.739
1.993LeuCys: 1.993 ± 0.989
4.65LeuAsp: 4.65 ± 0.331
3.321LeuGlu: 3.321 ± 0.463
2.325LeuPhe: 2.325 ± 0.626
2.989LeuGly: 2.989 ± 0.1
2.657LeuHis: 2.657 ± 0.791
3.321LeuIle: 3.321 ± 0.593
4.318LeuLys: 4.318 ± 0.56
6.974LeuLeu: 6.974 ± 0.823
0.996LeuMet: 0.996 ± 0.494
6.642LeuAsn: 6.642 ± 1.98
4.982LeuPro: 4.982 ± 1.221
2.325LeuGln: 2.325 ± 0.957
5.314LeuArg: 5.314 ± 0.529
12.953LeuSer: 12.953 ± 2.015
7.971LeuThr: 7.971 ± 0.793
5.314LeuVal: 5.314 ± 0.526
0.0LeuTrp: 0.0 ± 0.0
3.653LeuTyr: 3.653 ± 0.23
0.0LeuXaa: 0.0 ± 0.0
Met
1.328MetAla: 1.328 ± 0.132
0.996MetCys: 0.996 ± 0.494
0.332MetAsp: 0.332 ± 0.165
0.664MetGlu: 0.664 ± 0.33
0.332MetPhe: 0.332 ± 0.363
0.664MetGly: 0.664 ± 0.198
0.332MetHis: 0.332 ± 0.165
0.664MetIle: 0.664 ± 0.33
0.664MetLys: 0.664 ± 0.33
1.661MetLeu: 1.661 ± 0.296
0.0MetMet: 0.0 ± 0.148
0.664MetAsn: 0.664 ± 0.198
0.996MetPro: 0.996 ± 0.494
0.996MetGln: 0.996 ± 0.561
0.664MetArg: 0.664 ± 0.726
1.993MetSer: 1.993 ± 0.461
0.332MetThr: 0.332 ± 0.165
0.664MetVal: 0.664 ± 0.33
0.332MetTrp: 0.332 ± 0.165
0.996MetTyr: 0.996 ± 0.561
0.0MetXaa: 0.0 ± 0.0
Asn
3.653AsnAla: 3.653 ± 0.298
0.664AsnCys: 0.664 ± 0.33
0.332AsnAsp: 0.332 ± 0.363
1.661AsnGlu: 1.661 ± 0.824
2.325AsnPhe: 2.325 ± 0.626
2.325AsnGly: 2.325 ± 0.098
0.332AsnHis: 0.332 ± 0.165
1.661AsnIle: 1.661 ± 0.231
1.661AsnLys: 1.661 ± 0.231
6.974AsnLeu: 6.974 ± 2.871
0.664AsnMet: 0.664 ± 0.198
1.993AsnAsn: 1.993 ± 0.066
3.985AsnPro: 3.985 ± 0.661
1.993AsnGln: 1.993 ± 0.461
1.993AsnArg: 1.993 ± 0.594
6.974AsnSer: 6.974 ± 0.232
3.985AsnThr: 3.985 ± 0.661
7.307AsnVal: 7.307 ± 1.651
0.664AsnTrp: 0.664 ± 0.198
1.661AsnTyr: 1.661 ± 0.759
0.0AsnXaa: 0.0 ± 0.0
Pro
2.657ProAla: 2.657 ± 1.32
0.332ProCys: 0.332 ± 0.165
3.653ProAsp: 3.653 ± 0.23
2.325ProGlu: 2.325 ± 0.429
1.993ProPhe: 1.993 ± 0.594
3.321ProGly: 3.321 ± 0.463
1.328ProHis: 1.328 ± 0.132
3.985ProIle: 3.985 ± 1.716
1.993ProLys: 1.993 ± 0.989
4.982ProLeu: 4.982 ± 0.694
0.0ProMet: 0.0 ± 0.0
3.321ProAsn: 3.321 ± 0.593
2.325ProPro: 2.325 ± 0.429
0.996ProGln: 0.996 ± 0.561
1.328ProArg: 1.328 ± 0.132
5.314ProSer: 5.314 ± 1.057
1.993ProThr: 1.993 ± 0.594
2.325ProVal: 2.325 ± 0.429
0.0ProTrp: 0.0 ± 0.0
1.993ProTyr: 1.993 ± 0.594
0.0ProXaa: 0.0 ± 0.0
Gln
0.0GlnAla: 0.0 ± 0.0
0.996GlnCys: 0.996 ± 0.033
4.982GlnAsp: 4.982 ± 1.417
1.328GlnGlu: 1.328 ± 0.659
0.996GlnPhe: 0.996 ± 0.033
3.321GlnGly: 3.321 ± 0.463
0.332GlnHis: 0.332 ± 0.165
1.328GlnIle: 1.328 ± 0.396
0.664GlnLys: 0.664 ± 0.33
2.989GlnLeu: 2.989 ± 0.627
0.0GlnMet: 0.0 ± 0.0
0.996GlnAsn: 0.996 ± 0.033
0.996GlnPro: 0.996 ± 0.561
0.664GlnGln: 0.664 ± 0.198
0.996GlnArg: 0.996 ± 0.033
2.657GlnSer: 2.657 ± 0.264
1.993GlnThr: 1.993 ± 0.594
4.318GlnVal: 4.318 ± 0.56
0.332GlnTrp: 0.332 ± 0.165
0.664GlnTyr: 0.664 ± 0.726
0.0GlnXaa: 0.0 ± 0.0
Arg
2.657ArgAla: 2.657 ± 0.263
1.328ArgCys: 1.328 ± 0.132
1.328ArgAsp: 1.328 ± 0.396
2.325ArgGlu: 2.325 ± 1.154
2.657ArgPhe: 2.657 ± 1.32
1.328ArgGly: 1.328 ± 0.396
1.328ArgHis: 1.328 ± 0.659
1.993ArgIle: 1.993 ± 0.461
3.653ArgLys: 3.653 ± 1.813
2.989ArgLeu: 2.989 ± 0.627
0.996ArgMet: 0.996 ± 0.561
1.661ArgAsn: 1.661 ± 0.231
1.993ArgPro: 1.993 ± 0.066
1.993ArgGln: 1.993 ± 0.461
5.314ArgArg: 5.314 ± 1.054
5.978ArgSer: 5.978 ± 1.384
1.661ArgThr: 1.661 ± 0.231
4.982ArgVal: 4.982 ± 1.417
0.332ArgTrp: 0.332 ± 0.165
1.328ArgTyr: 1.328 ± 0.132
0.0ArgXaa: 0.0 ± 0.0
Ser
4.65SerAla: 4.65 ± 1.386
1.661SerCys: 1.661 ± 0.824
6.642SerAsp: 6.642 ± 1.714
5.314SerGlu: 5.314 ± 0.001
5.978SerPhe: 5.978 ± 0.199
4.318SerGly: 4.318 ± 0.032
4.65SerHis: 4.65 ± 2.308
6.31SerIle: 6.31 ± 2.145
3.985SerLys: 3.985 ± 0.395
11.292SerLeu: 11.292 ± 2.839
0.996SerMet: 0.996 ± 0.494
4.65SerAsn: 4.65 ± 0.331
3.653SerPro: 3.653 ± 0.825
3.653SerGln: 3.653 ± 0.23
5.646SerArg: 5.646 ± 0.691
9.631SerSer: 9.631 ± 0.558
4.318SerThr: 4.318 ± 1.551
10.96SerVal: 10.96 ± 3.532
0.996SerTrp: 0.996 ± 0.033
2.989SerTyr: 2.989 ± 0.428
0.0SerXaa: 0.0 ± 0.0
Thr
2.989ThrAla: 2.989 ± 0.1
1.661ThrCys: 1.661 ± 0.824
4.982ThrAsp: 4.982 ± 0.694
3.653ThrGlu: 3.653 ± 0.23
1.661ThrPhe: 1.661 ± 0.231
2.989ThrGly: 2.989 ± 0.1
2.657ThrHis: 2.657 ± 0.264
3.985ThrIle: 3.985 ± 1.716
2.325ThrLys: 2.325 ± 0.098
7.639ThrLeu: 7.639 ± 0.431
1.661ThrMet: 1.661 ± 0.231
3.653ThrAsn: 3.653 ± 2.936
2.657ThrPro: 2.657 ± 0.263
1.993ThrGln: 1.993 ± 0.066
3.653ThrArg: 3.653 ± 1.285
4.65ThrSer: 4.65 ± 1.386
4.65ThrThr: 4.65 ± 1.914
4.65ThrVal: 4.65 ± 0.859
0.996ThrTrp: 0.996 ± 0.033
1.993ThrTyr: 1.993 ± 0.594
0.0ThrXaa: 0.0 ± 0.0
Val
6.31ValAla: 6.31 ± 0.493
2.325ValCys: 2.325 ± 1.154
6.31ValAsp: 6.31 ± 2.076
4.318ValGlu: 4.318 ± 1.087
6.642ValPhe: 6.642 ± 0.13
3.985ValGly: 3.985 ± 0.133
1.993ValHis: 1.993 ± 0.989
3.653ValIle: 3.653 ± 1.881
5.314ValLys: 5.314 ± 1.582
6.31ValLeu: 6.31 ± 0.562
1.328ValMet: 1.328 ± 0.659
3.653ValAsn: 3.653 ± 0.298
3.653ValPro: 3.653 ± 0.298
1.993ValGln: 1.993 ± 0.066
5.978ValArg: 5.978 ± 0.856
9.631ValSer: 9.631 ± 1.025
7.307ValThr: 7.307 ± 0.595
6.31ValVal: 6.31 ± 1.021
0.664ValTrp: 0.664 ± 0.198
2.657ValTyr: 2.657 ± 0.263
0.0ValXaa: 0.0 ± 0.0
Trp
0.332TrpAla: 0.332 ± 0.165
0.332TrpCys: 0.332 ± 0.165
0.332TrpAsp: 0.332 ± 0.165
0.664TrpGlu: 0.664 ± 0.198
0.664TrpPhe: 0.664 ± 0.198
0.332TrpGly: 0.332 ± 0.165
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
0.664TrpLys: 0.664 ± 0.33
1.993TrpLeu: 1.993 ± 0.989
0.332TrpMet: 0.332 ± 0.363
0.332TrpAsn: 0.332 ± 0.363
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
0.332TrpArg: 0.332 ± 0.363
0.996TrpSer: 0.996 ± 0.494
0.996TrpThr: 0.996 ± 0.033
0.996TrpVal: 0.996 ± 0.561
0.332TrpTrp: 0.332 ± 0.363
0.664TrpTyr: 0.664 ± 0.33
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.993TyrAla: 1.993 ± 0.461
0.664TyrCys: 0.664 ± 0.33
2.657TyrAsp: 2.657 ± 0.791
1.661TyrGlu: 1.661 ± 1.814
1.993TyrPhe: 1.993 ± 0.461
1.661TyrGly: 1.661 ± 0.759
0.332TyrHis: 0.332 ± 0.165
0.996TyrIle: 0.996 ± 0.494
1.328TyrLys: 1.328 ± 0.396
2.989TyrLeu: 2.989 ± 0.1
0.996TyrMet: 0.996 ± 0.561
0.996TyrAsn: 0.996 ± 0.033
2.325TyrPro: 2.325 ± 0.626
0.332TyrGln: 0.332 ± 0.165
2.989TyrArg: 2.989 ± 0.627
3.321TyrSer: 3.321 ± 0.463
2.989TyrThr: 2.989 ± 0.627
3.321TyrVal: 3.321 ± 1.121
0.0TyrTrp: 0.0 ± 0.0
0.664TyrTyr: 0.664 ± 0.33
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (3012 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski