Amino acid dipepetide frequency for Wallemia mellicola (strain ATCC MYA-4683 / CBS 633.66) (Wallemia sebi (CBS 633.66))

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	5.788AlaAla: 5.788 ± 0.069	0.77AlaCys: 0.77 ± 0.022	3.467AlaAsp: 3.467 ± 0.043	3.994AlaGlu: 3.994 ± 0.048	3.029AlaPhe: 3.029 ± 0.038	4.26AlaGly: 4.26 ± 0.058	1.553AlaHis: 1.553 ± 0.029	4.604AlaIle: 4.604 ± 0.051	4.239AlaLys: 4.239 ± 0.054	7.086AlaLeu: 7.086 ± 0.067	1.524AlaMet: 1.524 ± 0.028	3.123AlaAsn: 3.123 ± 0.035	3.363AlaPro: 3.363 ± 0.054	3.018AlaGln: 3.018 ± 0.039	3.548AlaArg: 3.548 ± 0.048	5.831AlaSer: 5.831 ± 0.066	4.134AlaThr: 4.134 ± 0.051	4.108AlaVal: 4.108 ± 0.051	0.738AlaTrp: 0.738 ± 0.019	2.13AlaTyr: 2.13 ± 0.032	0.0AlaXaa: 0.0 ± 0.0
Cys	0.71CysAla: 0.71 ± 0.019	0.189CysCys: 0.189 ± 0.01	0.595CysAsp: 0.595 ± 0.017	0.524CysGlu: 0.524 ± 0.018	0.435CysPhe: 0.435 ± 0.02	0.721CysGly: 0.721 ± 0.024	0.259CysHis: 0.259 ± 0.012	0.657CysIle: 0.657 ± 0.019	0.562CysLys: 0.562 ± 0.017	1.109CysLeu: 1.109 ± 0.024	0.217CysMet: 0.217 ± 0.009	0.462CysAsn: 0.462 ± 0.018	0.484CysPro: 0.484 ± 0.017	0.382CysGln: 0.382 ± 0.013	0.539CysArg: 0.539 ± 0.017	0.771CysSer: 0.771 ± 0.019	0.605CysThr: 0.605 ± 0.016	0.682CysVal: 0.682 ± 0.017	0.149CysTrp: 0.149 ± 0.009	0.356CysTyr: 0.356 ± 0.013	0.0CysXaa: 0.0 ± 0.0
Asp	4.144AspAla: 4.144 ± 0.047	0.57AspCys: 0.57 ± 0.018	5.092AspAsp: 5.092 ± 0.07	5.236AspGlu: 5.236 ± 0.06	2.333AspPhe: 2.333 ± 0.031	3.489AspGly: 3.489 ± 0.044	1.129AspHis: 1.129 ± 0.023	4.082AspIle: 4.082 ± 0.051	3.847AspLys: 3.847 ± 0.049	5.503AspLeu: 5.503 ± 0.045	1.174AspMet: 1.174 ± 0.023	3.301AspAsn: 3.301 ± 0.048	2.481AspPro: 2.481 ± 0.035	2.122AspGln: 2.122 ± 0.032	2.679AspArg: 2.679 ± 0.037	4.453AspSer: 4.453 ± 0.051	3.006AspThr: 3.006 ± 0.036	3.98AspVal: 3.98 ± 0.047	0.77AspTrp: 0.77 ± 0.02	2.048AspTyr: 2.048 ± 0.03	0.0AspXaa: 0.0 ± 0.0
Glu	4.531GluAla: 4.531 ± 0.046	0.657GluCys: 0.657 ± 0.018	4.575GluAsp: 4.575 ± 0.054	6.083GluGlu: 6.083 ± 0.093	2.27GluPhe: 2.27 ± 0.036	3.333GluGly: 3.333 ± 0.042	1.424GluHis: 1.424 ± 0.031	3.885GluIle: 3.885 ± 0.049	4.684GluLys: 4.684 ± 0.057	5.875GluLeu: 5.875 ± 0.055	1.456GluMet: 1.456 ± 0.025	3.28GluAsn: 3.28 ± 0.039	2.234GluPro: 2.234 ± 0.035	2.87GluGln: 2.87 ± 0.046	3.838GluArg: 3.838 ± 0.052	4.863GluSer: 4.863 ± 0.052	3.218GluThr: 3.218 ± 0.039	3.418GluVal: 3.418 ± 0.041	0.761GluTrp: 0.761 ± 0.021	1.96GluTyr: 1.96 ± 0.032	0.0GluXaa: 0.0 ± 0.0
Phe	2.717PheAla: 2.717 ± 0.042	0.477PheCys: 0.477 ± 0.015	2.712PheAsp: 2.712 ± 0.039	2.48PheGlu: 2.48 ± 0.033	1.503PhePhe: 1.503 ± 0.032	2.757PheGly: 2.757 ± 0.051	0.77PheHis: 0.77 ± 0.018	2.419PheIle: 2.419 ± 0.038	2.486PheLys: 2.486 ± 0.037	3.173PheLeu: 3.173 ± 0.047	0.765PheMet: 0.765 ± 0.018	2.295PheAsn: 2.295 ± 0.035	1.521PhePro: 1.521 ± 0.027	1.211PheGln: 1.211 ± 0.023	1.678PheArg: 1.678 ± 0.028	3.099PheSer: 3.099 ± 0.041	2.241PheThr: 2.241 ± 0.036	2.4PheVal: 2.4 ± 0.037	0.507PheTrp: 0.507 ± 0.015	1.264PheTyr: 1.264 ± 0.025	0.0PheXaa: 0.0 ± 0.0
Gly	3.776GlyAla: 3.776 ± 0.052	0.742GlyCys: 0.742 ± 0.02	3.135GlyAsp: 3.135 ± 0.043	3.216GlyGlu: 3.216 ± 0.046	2.477GlyPhe: 2.477 ± 0.039	4.191GlyGly: 4.191 ± 0.068	1.385GlyHis: 1.385 ± 0.042	3.486GlyIle: 3.486 ± 0.049	3.515GlyLys: 3.515 ± 0.044	5.439GlyLeu: 5.439 ± 0.054	1.302GlyMet: 1.302 ± 0.03	2.422GlyAsn: 2.422 ± 0.035	2.056GlyPro: 2.056 ± 0.037	2.172GlyGln: 2.172 ± 0.037	2.896GlyArg: 2.896 ± 0.036	4.535GlySer: 4.535 ± 0.055	3.111GlyThr: 3.111 ± 0.04	3.871GlyVal: 3.871 ± 0.049	0.854GlyTrp: 0.854 ± 0.021	1.999GlyTyr: 1.999 ± 0.032	0.0GlyXaa: 0.0 ± 0.0
His	1.434HisAla: 1.434 ± 0.027	0.262HisCys: 0.262 ± 0.011	1.214HisAsp: 1.214 ± 0.022	1.233HisGlu: 1.233 ± 0.026	0.924HisPhe: 0.924 ± 0.02	1.254HisGly: 1.254 ± 0.036	0.735HisHis: 0.735 ± 0.024	1.389HisIle: 1.389 ± 0.026	1.318HisLys: 1.318 ± 0.025	2.38HisLeu: 2.38 ± 0.035	0.415HisMet: 0.415 ± 0.014	1.086HisAsn: 1.086 ± 0.024	1.394HisPro: 1.394 ± 0.026	1.02HisGln: 1.02 ± 0.022	1.156HisArg: 1.156 ± 0.025	2.012HisSer: 2.012 ± 0.038	1.273HisThr: 1.273 ± 0.026	1.251HisVal: 1.251 ± 0.027	0.264HisTrp: 0.264 ± 0.011	0.753HisTyr: 0.753 ± 0.019	0.0HisXaa: 0.0 ± 0.0
Ile	4.39IleAla: 4.39 ± 0.054	0.735IleCys: 0.735 ± 0.019	4.136IleAsp: 4.136 ± 0.046	4.089IleGlu: 4.089 ± 0.045	2.142IlePhe: 2.142 ± 0.033	3.464IleGly: 3.464 ± 0.04	1.386IleHis: 1.386 ± 0.024	3.537IleIle: 3.537 ± 0.047	3.776IleLys: 3.776 ± 0.041	5.361IleLeu: 5.361 ± 0.054	1.101IleMet: 1.101 ± 0.021	3.174IleAsn: 3.174 ± 0.036	3.341IlePro: 3.341 ± 0.045	2.357IleGln: 2.357 ± 0.035	2.922IleArg: 2.922 ± 0.038	4.927IleSer: 4.927 ± 0.05	3.254IleThr: 3.254 ± 0.043	3.554IleVal: 3.554 ± 0.044	0.711IleTrp: 0.711 ± 0.019	1.835IleTyr: 1.835 ± 0.03	0.0IleXaa: 0.0 ± 0.0
Lys	4.561LysAla: 4.561 ± 0.051	0.602LysCys: 0.602 ± 0.019	3.861LysAsp: 3.861 ± 0.044	4.731LysGlu: 4.731 ± 0.061	2.092LysPhe: 2.092 ± 0.038	3.098LysGly: 3.098 ± 0.041	1.529LysHis: 1.529 ± 0.025	3.26LysIle: 3.26 ± 0.038	4.714LysLys: 4.714 ± 0.076	6.054LysLeu: 6.054 ± 0.062	1.287LysMet: 1.287 ± 0.028	2.878LysAsn: 2.878 ± 0.036	3.213LysPro: 3.213 ± 0.053	2.903LysGln: 2.903 ± 0.045	3.933LysArg: 3.933 ± 0.051	5.393LysSer: 5.393 ± 0.056	3.334LysThr: 3.334 ± 0.04	3.545LysVal: 3.545 ± 0.039	0.688LysTrp: 0.688 ± 0.02	1.977LysTyr: 1.977 ± 0.032	0.0LysXaa: 0.0 ± 0.0
Leu	6.804LeuAla: 6.804 ± 0.062	1.012LeuCys: 1.012 ± 0.023	5.89LeuAsp: 5.89 ± 0.048	5.988LeuGlu: 5.988 ± 0.062	3.541LeuPhe: 3.541 ± 0.049	5.191LeuGly: 5.191 ± 0.059	2.172LeuHis: 2.172 ± 0.034	5.414LeuIle: 5.414 ± 0.061	5.868LeuLys: 5.868 ± 0.056	8.773LeuLeu: 8.773 ± 0.069	1.759LeuMet: 1.759 ± 0.029	4.997LeuAsn: 4.997 ± 0.055	4.896LeuPro: 4.896 ± 0.055	3.808LeuGln: 3.808 ± 0.044	5.006LeuArg: 5.006 ± 0.059	8.429LeuSer: 8.429 ± 0.079	5.133LeuThr: 5.133 ± 0.055	5.293LeuVal: 5.293 ± 0.059	0.941LeuTrp: 0.941 ± 0.021	2.611LeuTyr: 2.611 ± 0.04	0.0LeuXaa: 0.0 ± 0.0
Met	1.436MetAla: 1.436 ± 0.029	0.18MetCys: 0.18 ± 0.01	1.138MetAsp: 1.138 ± 0.025	1.165MetGlu: 1.165 ± 0.025	0.757MetPhe: 0.757 ± 0.021	1.108MetGly: 1.108 ± 0.025	0.417MetHis: 0.417 ± 0.014	1.139MetIle: 1.139 ± 0.026	1.29MetLys: 1.29 ± 0.025	1.847MetLeu: 1.847 ± 0.029	0.529MetMet: 0.529 ± 0.016	0.984MetAsn: 0.984 ± 0.023	1.0MetPro: 1.0 ± 0.023	0.885MetGln: 0.885 ± 0.021	1.158MetArg: 1.158 ± 0.026	2.114MetSer: 2.114 ± 0.032	1.273MetThr: 1.273 ± 0.019	1.042MetVal: 1.042 ± 0.022	0.173MetTrp: 0.173 ± 0.008	0.524MetTyr: 0.524 ± 0.017	0.0MetXaa: 0.0 ± 0.0
Asn	3.496AsnAla: 3.496 ± 0.041	0.466AsnCys: 0.466 ± 0.017	3.387AsnAsp: 3.387 ± 0.046	3.385AsnGlu: 3.385 ± 0.04	1.734AsnPhe: 1.734 ± 0.032	2.806AsnGly: 2.806 ± 0.041	1.089AsnHis: 1.089 ± 0.02	3.04AsnIle: 3.04 ± 0.034	3.386AsnLys: 3.386 ± 0.04	4.613AsnLeu: 4.613 ± 0.044	0.974AsnMet: 0.974 ± 0.022	3.036AsnAsn: 3.036 ± 0.041	2.354AsnPro: 2.354 ± 0.03	2.116AsnGln: 2.116 ± 0.037	2.187AsnArg: 2.187 ± 0.024	4.008AsnSer: 4.008 ± 0.046	2.884AsnThr: 2.884 ± 0.035	3.159AsnVal: 3.159 ± 0.048	0.646AsnTrp: 0.646 ± 0.019	1.66AsnTyr: 1.66 ± 0.031	0.0AsnXaa: 0.0 ± 0.0
Pro	3.451ProAla: 3.451 ± 0.06	0.314ProCys: 0.314 ± 0.015	2.474ProAsp: 2.474 ± 0.035	3.163ProGlu: 3.163 ± 0.038	1.915ProPhe: 1.915 ± 0.031	2.401ProGly: 2.401 ± 0.04	1.094ProHis: 1.094 ± 0.025	2.856ProIle: 2.856 ± 0.041	2.769ProLys: 2.769 ± 0.039	4.137ProLeu: 4.137 ± 0.047	0.817ProMet: 0.817 ± 0.021	2.266ProAsn: 2.266 ± 0.037	3.793ProPro: 3.793 ± 0.087	2.285ProGln: 2.285 ± 0.04	2.234ProArg: 2.234 ± 0.039	5.138ProSer: 5.138 ± 0.06	3.429ProThr: 3.429 ± 0.042	2.712ProVal: 2.712 ± 0.044	0.462ProTrp: 0.462 ± 0.015	1.478ProTyr: 1.478 ± 0.027	0.0ProXaa: 0.0 ± 0.0
Gln	3.103GlnAla: 3.103 ± 0.043	0.346GlnCys: 0.346 ± 0.013	2.221GlnAsp: 2.221 ± 0.034	2.564GlnGlu: 2.564 ± 0.038	1.573GlnPhe: 1.573 ± 0.031	1.945GlnGly: 1.945 ± 0.037	1.058GlnHis: 1.058 ± 0.025	2.349GlnIle: 2.349 ± 0.035	2.423GlnLys: 2.423 ± 0.039	4.21GlnLeu: 4.21 ± 0.044	0.935GlnMet: 0.935 ± 0.024	1.922GlnAsn: 1.922 ± 0.035	2.424GlnPro: 2.424 ± 0.045	3.044GlnGln: 3.044 ± 0.088	2.407GlnArg: 2.407 ± 0.037	4.026GlnSer: 4.026 ± 0.053	2.376GlnThr: 2.376 ± 0.034	2.329GlnVal: 2.329 ± 0.035	0.413GlnTrp: 0.413 ± 0.014	1.125GlnTyr: 1.125 ± 0.029	0.0GlnXaa: 0.0 ± 0.0
Arg	3.429ArgAla: 3.429 ± 0.042	0.544ArgCys: 0.544 ± 0.019	2.931ArgAsp: 2.931 ± 0.042	3.285ArgGlu: 3.285 ± 0.056	1.918ArgPhe: 1.918 ± 0.032	2.745ArgGly: 2.745 ± 0.043	1.197ArgHis: 1.197 ± 0.024	2.92ArgIle: 2.92 ± 0.041	3.735ArgLys: 3.735 ± 0.053	4.912ArgLeu: 4.912 ± 0.056	1.194ArgMet: 1.194 ± 0.024	2.463ArgAsn: 2.463 ± 0.036	2.291ArgPro: 2.291 ± 0.033	2.429ArgGln: 2.429 ± 0.035	3.761ArgArg: 3.761 ± 0.058	4.263ArgSer: 4.263 ± 0.052	2.718ArgThr: 2.718 ± 0.035	2.966ArgVal: 2.966 ± 0.041	0.616ArgTrp: 0.616 ± 0.017	1.592ArgTyr: 1.592 ± 0.03	0.0ArgXaa: 0.0 ± 0.0
Ser	5.683SerAla: 5.683 ± 0.063	0.775SerCys: 0.775 ± 0.021	4.849SerAsp: 4.849 ± 0.051	4.582SerGlu: 4.582 ± 0.047	3.332SerPhe: 3.332 ± 0.044	4.521SerGly: 4.521 ± 0.049	1.974SerHis: 1.974 ± 0.031	5.354SerIle: 5.354 ± 0.055	5.315SerLys: 5.315 ± 0.052	7.974SerLeu: 7.974 ± 0.067	1.57SerMet: 1.57 ± 0.026	4.701SerAsn: 4.701 ± 0.046	4.277SerPro: 4.277 ± 0.065	3.828SerGln: 3.828 ± 0.05	4.278SerArg: 4.278 ± 0.048	8.807SerSer: 8.807 ± 0.113	5.84SerThr: 5.84 ± 0.059	4.621SerVal: 4.621 ± 0.047	0.9SerTrp: 0.9 ± 0.022	2.422SerTyr: 2.422 ± 0.037	0.0SerXaa: 0.0 ± 0.0
Thr	3.888ThrAla: 3.888 ± 0.047	0.559ThrCys: 0.559 ± 0.018	2.808ThrAsp: 2.808 ± 0.038	3.013ThrGlu: 3.013 ± 0.033	2.363ThrPhe: 2.363 ± 0.032	3.329ThrGly: 3.329 ± 0.048	1.287ThrHis: 1.287 ± 0.022	3.682ThrIle: 3.682 ± 0.043	3.323ThrLys: 3.323 ± 0.041	5.706ThrLeu: 5.706 ± 0.059	1.019ThrMet: 1.019 ± 0.021	2.803ThrAsn: 2.803 ± 0.038	3.723ThrPro: 3.723 ± 0.051	2.328ThrGln: 2.328 ± 0.033	2.774ThrArg: 2.774 ± 0.04	5.311ThrSer: 5.311 ± 0.059	3.743ThrThr: 3.743 ± 0.049	3.2ThrVal: 3.2 ± 0.041	0.569ThrTrp: 0.569 ± 0.018	1.614ThrTyr: 1.614 ± 0.029	0.0ThrXaa: 0.0 ± 0.0
Val	4.124ValAla: 4.124 ± 0.044	0.688ValCys: 0.688 ± 0.018	4.21ValAsp: 4.21 ± 0.045	4.002ValGlu: 4.002 ± 0.052	2.329ValPhe: 2.329 ± 0.037	3.489ValGly: 3.489 ± 0.042	1.322ValHis: 1.322 ± 0.025	3.555ValIle: 3.555 ± 0.045	3.768ValLys: 3.768 ± 0.048	5.302ValLeu: 5.302 ± 0.054	1.219ValMet: 1.219 ± 0.023	2.87ValAsn: 2.87 ± 0.038	2.625ValPro: 2.625 ± 0.038	2.333ValGln: 2.333 ± 0.038	2.76ValArg: 2.76 ± 0.036	4.311ValSer: 4.311 ± 0.052	2.98ValThr: 2.98 ± 0.043	3.839ValVal: 3.839 ± 0.054	0.674ValTrp: 0.674 ± 0.019	1.881ValTyr: 1.881 ± 0.031	0.0ValXaa: 0.0 ± 0.0
Trp	0.688TrpAla: 0.688 ± 0.017	0.157TrpCys: 0.157 ± 0.009	0.731TrpAsp: 0.731 ± 0.024	0.626TrpGlu: 0.626 ± 0.018	0.493TrpPhe: 0.493 ± 0.015	0.622TrpGly: 0.622 ± 0.018	0.263TrpHis: 0.263 ± 0.011	0.704TrpIle: 0.704 ± 0.018	0.775TrpLys: 0.775 ± 0.02	1.105TrpLeu: 1.105 ± 0.025	0.295TrpMet: 0.295 ± 0.012	0.612TrpAsn: 0.612 ± 0.016	0.399TrpPro: 0.399 ± 0.015	0.433TrpGln: 0.433 ± 0.016	0.641TrpArg: 0.641 ± 0.017	1.017TrpSer: 1.017 ± 0.023	0.671TrpThr: 0.671 ± 0.021	0.598TrpVal: 0.598 ± 0.017	0.188TrpTrp: 0.188 ± 0.01	0.371TrpTyr: 0.371 ± 0.014	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.153TyrAla: 2.153 ± 0.033	0.364TyrCys: 0.364 ± 0.013	2.013TyrAsp: 2.013 ± 0.033	1.855TyrGlu: 1.855 ± 0.029	1.317TyrPhe: 1.317 ± 0.024	1.854TyrGly: 1.854 ± 0.035	0.725TyrHis: 0.725 ± 0.017	1.862TyrIle: 1.862 ± 0.029	1.861TyrLys: 1.861 ± 0.032	2.97TyrLeu: 2.97 ± 0.032	0.607TyrMet: 0.607 ± 0.017	1.752TyrAsn: 1.752 ± 0.031	1.316TyrPro: 1.316 ± 0.025	1.251TyrGln: 1.251 ± 0.024	1.512TyrArg: 1.512 ± 0.029	2.294TyrSer: 2.294 ± 0.032	1.816TyrThr: 1.816 ± 0.029	1.712TyrVal: 1.712 ± 0.027	0.364TyrTrp: 0.364 ± 0.014	1.05TyrTyr: 1.05 ± 0.024	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 5262 proteins (2223108 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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