Amino acid dipepetide frequency for Canis familiaris papillomavirus 13

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.17AlaAla: 4.17 ± 0.965
1.137AlaCys: 1.137 ± 0.525
4.549AlaAsp: 4.549 ± 1.278
3.791AlaGlu: 3.791 ± 0.844
1.895AlaPhe: 1.895 ± 0.916
3.033AlaGly: 3.033 ± 0.481
1.895AlaHis: 1.895 ± 0.347
1.137AlaIle: 1.137 ± 0.653
3.033AlaLys: 3.033 ± 1.173
3.412AlaLeu: 3.412 ± 1.084
0.379AlaMet: 0.379 ± 0.344
1.516AlaAsn: 1.516 ± 1.377
5.686AlaPro: 5.686 ± 1.322
1.895AlaGln: 1.895 ± 0.728
3.412AlaArg: 3.412 ± 0.946
2.654AlaSer: 2.654 ± 0.456
3.033AlaThr: 3.033 ± 0.95
4.17AlaVal: 4.17 ± 1.947
0.379AlaTrp: 0.379 ± 0.322
1.516AlaTyr: 1.516 ± 0.881
0.0AlaXaa: 0.0 ± 0.0
Cys
0.758CysAla: 0.758 ± 0.465
1.516CysCys: 1.516 ± 0.992
0.379CysAsp: 0.379 ± 0.344
0.758CysGlu: 0.758 ± 0.465
1.137CysPhe: 1.137 ± 0.685
1.895CysGly: 1.895 ± 0.779
0.758CysHis: 0.758 ± 0.57
1.895CysIle: 1.895 ± 0.847
2.274CysLys: 2.274 ± 0.754
3.412CysLeu: 3.412 ± 1.259
0.0CysMet: 0.0 ± 0.0
0.379CysAsn: 0.379 ± 0.322
0.758CysPro: 0.758 ± 0.689
0.379CysGln: 0.379 ± 0.353
3.412CysArg: 3.412 ± 0.666
1.137CysSer: 1.137 ± 0.708
0.758CysThr: 0.758 ± 0.756
1.137CysVal: 1.137 ± 0.473
1.137CysTrp: 1.137 ± 0.516
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
3.412AspAla: 3.412 ± 0.896
2.654AspCys: 2.654 ± 1.016
4.549AspAsp: 4.549 ± 1.584
4.17AspGlu: 4.17 ± 0.985
3.412AspPhe: 3.412 ± 0.711
5.307AspGly: 5.307 ± 2.104
2.274AspHis: 2.274 ± 0.777
3.033AspIle: 3.033 ± 1.192
2.274AspLys: 2.274 ± 0.696
6.444AspLeu: 6.444 ± 1.386
0.379AspMet: 0.379 ± 0.322
3.412AspAsn: 3.412 ± 0.917
6.823AspPro: 6.823 ± 1.794
0.758AspGln: 0.758 ± 0.394
0.758AspArg: 0.758 ± 0.394
6.065AspSer: 6.065 ± 1.572
3.412AspThr: 3.412 ± 0.988
4.17AspVal: 4.17 ± 1.162
2.274AspTrp: 2.274 ± 0.746
0.758AspTyr: 0.758 ± 0.359
0.0AspXaa: 0.0 ± 0.0
Glu
4.928GluAla: 4.928 ± 1.419
1.137GluCys: 1.137 ± 0.45
6.823GluAsp: 6.823 ± 2.031
9.477GluGlu: 9.477 ± 3.057
2.274GluPhe: 2.274 ± 0.504
5.686GluGly: 5.686 ± 2.249
0.758GluHis: 0.758 ± 0.68
3.033GluIle: 3.033 ± 1.153
2.274GluLys: 2.274 ± 0.754
3.412GluLeu: 3.412 ± 1.29
1.516GluMet: 1.516 ± 0.443
3.033GluAsn: 3.033 ± 0.979
2.654GluPro: 2.654 ± 1.068
2.274GluGln: 2.274 ± 0.486
3.791GluArg: 3.791 ± 1.507
4.549GluSer: 4.549 ± 0.667
1.895GluThr: 1.895 ± 1.188
2.654GluVal: 2.654 ± 0.577
0.379GluTrp: 0.379 ± 0.322
0.758GluTyr: 0.758 ± 0.441
0.0GluXaa: 0.0 ± 0.0
Phe
1.895PheAla: 1.895 ± 0.707
1.895PheCys: 1.895 ± 0.967
5.307PheAsp: 5.307 ± 1.477
4.549PheGlu: 4.549 ± 2.324
3.791PhePhe: 3.791 ± 0.622
3.412PheGly: 3.412 ± 0.748
0.379PheHis: 0.379 ± 0.348
0.758PheIle: 0.758 ± 0.689
2.274PheLys: 2.274 ± 0.852
5.307PheLeu: 5.307 ± 0.728
0.0PheMet: 0.0 ± 0.0
1.137PheAsn: 1.137 ± 0.715
2.274PhePro: 2.274 ± 0.52
3.033PheGln: 3.033 ± 1.238
2.654PheArg: 2.654 ± 0.93
2.654PheSer: 2.654 ± 0.724
2.274PheThr: 2.274 ± 0.86
2.654PheVal: 2.654 ± 0.947
1.137PheTrp: 1.137 ± 0.394
1.516PheTyr: 1.516 ± 0.788
0.0PheXaa: 0.0 ± 0.0
Gly
1.137GlyAla: 1.137 ± 0.68
1.137GlyCys: 1.137 ± 0.45
6.065GlyAsp: 6.065 ± 1.092
6.065GlyGlu: 6.065 ± 1.264
3.791GlyPhe: 3.791 ± 0.748
15.163GlyGly: 15.163 ± 4.188
1.516GlyHis: 1.516 ± 0.574
2.654GlyIle: 2.654 ± 0.456
3.033GlyLys: 3.033 ± 0.905
3.791GlyLeu: 3.791 ± 0.77
1.137GlyMet: 1.137 ± 0.691
4.549GlyAsn: 4.549 ± 0.654
6.065GlyPro: 6.065 ± 2.143
3.033GlyGln: 3.033 ± 1.087
9.098GlyArg: 9.098 ± 3.076
7.582GlySer: 7.582 ± 0.833
6.444GlyThr: 6.444 ± 2.213
4.17GlyVal: 4.17 ± 1.365
1.137GlyTrp: 1.137 ± 0.591
1.137GlyTyr: 1.137 ± 0.404
0.0GlyXaa: 0.0 ± 0.0
His
2.654HisAla: 2.654 ± 0.71
0.379HisCys: 0.379 ± 0.34
0.758HisAsp: 0.758 ± 0.359
1.895HisGlu: 1.895 ± 0.658
1.516HisPhe: 1.516 ± 0.625
1.895HisGly: 1.895 ± 0.935
0.758HisHis: 0.758 ± 0.387
0.379HisIle: 0.379 ± 0.344
0.758HisLys: 0.758 ± 0.412
1.137HisLeu: 1.137 ± 0.588
1.137HisMet: 1.137 ± 0.554
0.379HisAsn: 0.379 ± 0.322
1.895HisPro: 1.895 ± 1.003
1.137HisGln: 1.137 ± 0.502
1.137HisArg: 1.137 ± 0.458
3.033HisSer: 3.033 ± 1.169
2.274HisThr: 2.274 ± 0.674
1.516HisVal: 1.516 ± 0.659
0.379HisTrp: 0.379 ± 0.344
2.274HisTyr: 2.274 ± 1.382
0.0HisXaa: 0.0 ± 0.0
Ile
1.516IleAla: 1.516 ± 0.543
0.0IleCys: 0.0 ± 0.0
1.516IleAsp: 1.516 ± 1.287
1.516IleGlu: 1.516 ± 0.883
1.895IlePhe: 1.895 ± 0.58
3.412IleGly: 3.412 ± 0.748
0.758IleHis: 0.758 ± 0.394
1.137IleIle: 1.137 ± 0.478
1.516IleLys: 1.516 ± 0.748
2.654IleLeu: 2.654 ± 0.877
0.379IleMet: 0.379 ± 0.348
1.137IleAsn: 1.137 ± 0.488
1.895IlePro: 1.895 ± 0.825
0.758IleGln: 0.758 ± 0.644
1.137IleArg: 1.137 ± 0.705
3.033IleSer: 3.033 ± 0.592
1.137IleThr: 1.137 ± 0.653
1.516IleVal: 1.516 ± 0.557
0.0IleTrp: 0.0 ± 0.0
1.137IleTyr: 1.137 ± 0.394
0.0IleXaa: 0.0 ± 0.0
Lys
2.654LysAla: 2.654 ± 0.867
1.516LysCys: 1.516 ± 0.803
1.516LysAsp: 1.516 ± 1.013
3.033LysGlu: 3.033 ± 1.041
2.654LysPhe: 2.654 ± 0.946
1.137LysGly: 1.137 ± 0.68
2.654LysHis: 2.654 ± 1.322
1.895LysIle: 1.895 ± 0.614
3.412LysLys: 3.412 ± 1.32
3.412LysLeu: 3.412 ± 1.012
1.895LysMet: 1.895 ± 0.869
1.516LysAsn: 1.516 ± 0.823
1.137LysPro: 1.137 ± 0.517
2.274LysGln: 2.274 ± 0.51
7.202LysArg: 7.202 ± 1.685
3.791LysSer: 3.791 ± 2.37
1.895LysThr: 1.895 ± 0.546
3.033LysVal: 3.033 ± 1.08
1.137LysTrp: 1.137 ± 0.488
1.137LysTyr: 1.137 ± 0.591
0.0LysXaa: 0.0 ± 0.0
Leu
3.412LeuAla: 3.412 ± 0.641
2.274LeuCys: 2.274 ± 0.833
6.065LeuAsp: 6.065 ± 1.531
5.307LeuGlu: 5.307 ± 1.016
5.307LeuPhe: 5.307 ± 1.503
7.582LeuGly: 7.582 ± 1.897
1.516LeuHis: 1.516 ± 0.528
1.137LeuIle: 1.137 ± 0.965
6.065LeuLys: 6.065 ± 1.0
6.065LeuLeu: 6.065 ± 1.653
3.033LeuMet: 3.033 ± 0.626
1.895LeuAsn: 1.895 ± 0.707
3.412LeuPro: 3.412 ± 0.973
4.17LeuGln: 4.17 ± 0.854
5.307LeuArg: 5.307 ± 1.967
9.477LeuSer: 9.477 ± 1.13
2.274LeuThr: 2.274 ± 0.837
4.17LeuVal: 4.17 ± 1.281
0.379LeuTrp: 0.379 ± 0.353
2.274LeuTyr: 2.274 ± 0.832
0.0LeuXaa: 0.0 ± 0.0
Met
1.137MetAla: 1.137 ± 0.551
0.379MetCys: 0.379 ± 0.344
1.137MetAsp: 1.137 ± 0.666
1.137MetGlu: 1.137 ± 0.468
1.137MetPhe: 1.137 ± 0.68
0.758MetGly: 0.758 ± 0.473
0.0MetHis: 0.0 ± 0.0
1.137MetIle: 1.137 ± 0.652
0.379MetLys: 0.379 ± 0.34
2.274MetLeu: 2.274 ± 0.788
0.0MetMet: 0.0 ± 0.0
0.758MetAsn: 0.758 ± 0.689
1.137MetPro: 1.137 ± 0.502
0.758MetGln: 0.758 ± 0.359
1.516MetArg: 1.516 ± 0.81
1.137MetSer: 1.137 ± 0.591
1.137MetThr: 1.137 ± 0.376
0.379MetVal: 0.379 ± 0.322
0.379MetTrp: 0.379 ± 0.348
0.758MetTyr: 0.758 ± 0.644
0.0MetXaa: 0.0 ± 0.0
Asn
3.033AsnAla: 3.033 ± 0.92
0.379AsnCys: 0.379 ± 0.541
1.516AsnAsp: 1.516 ± 0.615
1.137AsnGlu: 1.137 ± 0.45
1.137AsnPhe: 1.137 ± 0.696
3.033AsnGly: 3.033 ± 0.895
0.758AsnHis: 0.758 ± 0.394
1.137AsnIle: 1.137 ± 0.715
2.274AsnLys: 2.274 ± 0.715
2.654AsnLeu: 2.654 ± 0.567
0.0AsnMet: 0.0 ± 0.0
2.274AsnAsn: 2.274 ± 1.268
3.791AsnPro: 3.791 ± 1.246
0.379AsnGln: 0.379 ± 0.344
1.895AsnArg: 1.895 ± 0.832
1.895AsnSer: 1.895 ± 0.392
2.274AsnThr: 2.274 ± 1.021
1.516AsnVal: 1.516 ± 0.611
0.0AsnTrp: 0.0 ± 0.0
1.895AsnTyr: 1.895 ± 0.63
0.0AsnXaa: 0.0 ± 0.0
Pro
6.444ProAla: 6.444 ± 1.698
0.758ProCys: 0.758 ± 0.431
7.202ProAsp: 7.202 ± 0.781
4.17ProGlu: 4.17 ± 1.019
1.137ProPhe: 1.137 ± 0.495
4.17ProGly: 4.17 ± 1.166
1.516ProHis: 1.516 ± 0.703
0.379ProIle: 0.379 ± 0.353
4.17ProLys: 4.17 ± 1.457
6.444ProLeu: 6.444 ± 1.884
0.758ProMet: 0.758 ± 0.394
1.516ProAsn: 1.516 ± 0.985
12.889ProPro: 12.889 ± 6.094
3.033ProGln: 3.033 ± 1.165
4.17ProArg: 4.17 ± 1.166
6.823ProSer: 6.823 ± 1.467
5.307ProThr: 5.307 ± 1.211
4.549ProVal: 4.549 ± 0.906
0.758ProTrp: 0.758 ± 0.695
1.516ProTyr: 1.516 ± 0.672
0.0ProXaa: 0.0 ± 0.0
Gln
2.274GlnAla: 2.274 ± 1.092
0.758GlnCys: 0.758 ± 0.456
2.274GlnAsp: 2.274 ± 1.264
1.895GlnGlu: 1.895 ± 0.74
2.654GlnPhe: 2.654 ± 0.64
5.307GlnGly: 5.307 ± 1.275
1.516GlnHis: 1.516 ± 0.638
0.379GlnIle: 0.379 ± 0.34
1.895GlnLys: 1.895 ± 1.005
4.17GlnLeu: 4.17 ± 1.748
1.895GlnMet: 1.895 ± 0.595
1.137GlnAsn: 1.137 ± 0.394
1.516GlnPro: 1.516 ± 0.746
1.516GlnGln: 1.516 ± 1.142
1.516GlnArg: 1.516 ± 1.391
2.654GlnSer: 2.654 ± 1.14
1.895GlnThr: 1.895 ± 0.488
1.137GlnVal: 1.137 ± 0.632
0.758GlnTrp: 0.758 ± 0.644
0.758GlnTyr: 0.758 ± 0.644
0.0GlnXaa: 0.0 ± 0.0
Arg
1.895ArgAla: 1.895 ± 0.738
2.654ArgCys: 2.654 ± 1.121
4.928ArgAsp: 4.928 ± 0.902
3.791ArgGlu: 3.791 ± 1.271
1.895ArgPhe: 1.895 ± 0.858
8.34ArgGly: 8.34 ± 3.512
1.895ArgHis: 1.895 ± 0.856
0.758ArgIle: 0.758 ± 0.412
3.791ArgLys: 3.791 ± 0.707
7.582ArgLeu: 7.582 ± 1.163
0.758ArgMet: 0.758 ± 0.706
1.895ArgAsn: 1.895 ± 0.937
4.928ArgPro: 4.928 ± 1.183
2.654ArgGln: 2.654 ± 1.224
6.444ArgArg: 6.444 ± 2.439
6.065ArgSer: 6.065 ± 1.219
3.412ArgThr: 3.412 ± 1.819
3.791ArgVal: 3.791 ± 1.293
0.379ArgTrp: 0.379 ± 0.378
0.758ArgTyr: 0.758 ± 0.695
0.0ArgXaa: 0.0 ± 0.0
Ser
3.033SerAla: 3.033 ± 0.901
1.516SerCys: 1.516 ± 0.662
4.17SerAsp: 4.17 ± 1.291
6.065SerGlu: 6.065 ± 0.966
3.791SerPhe: 3.791 ± 0.752
5.686SerGly: 5.686 ± 1.176
3.791SerHis: 3.791 ± 0.76
1.895SerIle: 1.895 ± 0.347
3.412SerLys: 3.412 ± 1.594
8.34SerLeu: 8.34 ± 1.15
0.758SerMet: 0.758 ± 0.359
1.895SerAsn: 1.895 ± 0.924
6.444SerPro: 6.444 ± 2.122
4.17SerGln: 4.17 ± 0.952
4.928SerArg: 4.928 ± 1.079
9.856SerSer: 9.856 ± 2.027
7.582SerThr: 7.582 ± 2.683
6.065SerVal: 6.065 ± 0.918
0.758SerTrp: 0.758 ± 0.412
0.379SerTyr: 0.379 ± 0.322
0.0SerXaa: 0.0 ± 0.0
Thr
2.274ThrAla: 2.274 ± 1.324
1.516ThrCys: 1.516 ± 0.76
2.274ThrAsp: 2.274 ± 0.435
0.758ThrGlu: 0.758 ± 0.622
5.307ThrPhe: 5.307 ± 1.188
6.065ThrGly: 6.065 ± 1.679
1.895ThrHis: 1.895 ± 0.392
2.274ThrIle: 2.274 ± 1.057
1.895ThrLys: 1.895 ± 0.658
3.412ThrLeu: 3.412 ± 0.831
0.758ThrMet: 0.758 ± 0.359
2.274ThrAsn: 2.274 ± 1.46
7.202ThrPro: 7.202 ± 1.545
1.895ThrGln: 1.895 ± 0.597
2.654ThrArg: 2.654 ± 0.832
4.17ThrSer: 4.17 ± 0.424
3.033ThrThr: 3.033 ± 1.017
4.17ThrVal: 4.17 ± 2.109
0.758ThrTrp: 0.758 ± 0.695
0.758ThrTyr: 0.758 ± 0.689
0.0ThrXaa: 0.0 ± 0.0
Val
4.17ValAla: 4.17 ± 1.13
1.516ValCys: 1.516 ± 0.746
3.412ValAsp: 3.412 ± 1.018
1.516ValGlu: 1.516 ± 0.467
2.274ValPhe: 2.274 ± 1.247
4.17ValGly: 4.17 ± 0.946
2.274ValHis: 2.274 ± 1.281
2.274ValIle: 2.274 ± 0.441
1.895ValLys: 1.895 ± 0.458
4.17ValLeu: 4.17 ± 1.393
1.137ValMet: 1.137 ± 0.45
1.516ValAsn: 1.516 ± 0.523
4.928ValPro: 4.928 ± 1.123
2.654ValGln: 2.654 ± 1.132
3.412ValArg: 3.412 ± 0.888
6.823ValSer: 6.823 ± 1.411
3.791ValThr: 3.791 ± 0.689
6.823ValVal: 6.823 ± 3.304
0.758ValTrp: 0.758 ± 0.466
1.137ValTyr: 1.137 ± 0.376
0.0ValXaa: 0.0 ± 0.0
Trp
0.758TrpAla: 0.758 ± 0.456
0.379TrpCys: 0.379 ± 0.378
0.758TrpAsp: 0.758 ± 0.441
1.137TrpGlu: 1.137 ± 1.043
0.379TrpPhe: 0.379 ± 0.322
0.379TrpGly: 0.379 ± 0.34
0.0TrpHis: 0.0 ± 0.0
0.379TrpIle: 0.379 ± 0.322
0.758TrpLys: 0.758 ± 0.465
1.516TrpLeu: 1.516 ± 0.922
0.0TrpMet: 0.0 ± 0.0
0.758TrpAsn: 0.758 ± 0.689
1.137TrpPro: 1.137 ± 0.685
0.379TrpGln: 0.379 ± 0.344
2.274TrpArg: 2.274 ± 0.892
0.379TrpSer: 0.379 ± 0.348
0.379TrpThr: 0.379 ± 0.353
1.516TrpVal: 1.516 ± 0.63
0.379TrpTrp: 0.379 ± 0.348
0.379TrpTyr: 0.379 ± 0.322
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.137TyrAla: 1.137 ± 0.632
0.379TyrCys: 0.379 ± 0.344
1.137TyrAsp: 1.137 ± 0.394
1.137TyrGlu: 1.137 ± 0.653
1.516TyrPhe: 1.516 ± 0.922
2.274TyrGly: 2.274 ± 0.989
0.379TyrHis: 0.379 ± 0.34
0.379TyrIle: 0.379 ± 0.322
1.516TyrLys: 1.516 ± 0.942
1.895TyrLeu: 1.895 ± 0.665
1.137TyrMet: 1.137 ± 0.965
0.0TyrAsn: 0.0 ± 0.0
1.137TyrPro: 1.137 ± 0.621
0.758TyrGln: 0.758 ± 0.412
1.895TyrArg: 1.895 ± 0.758
0.758TyrSer: 0.758 ± 0.359
1.137TyrThr: 1.137 ± 0.691
1.516TyrVal: 1.516 ± 0.234
0.758TyrTrp: 0.758 ± 0.689
0.758TyrTyr: 0.758 ± 0.695
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 7 proteins (2639 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski