Amino acid dipepetide frequency for Apaloderma vittatum (Bar-tailed trogon)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.686AlaAla: 5.686 ± 0.066
1.304AlaCys: 1.304 ± 0.025
3.032AlaAsp: 3.032 ± 0.032
4.635AlaGlu: 4.635 ± 0.048
2.674AlaPhe: 2.674 ± 0.03
3.833AlaGly: 3.833 ± 0.045
1.344AlaHis: 1.344 ± 0.02
3.099AlaIle: 3.099 ± 0.032
3.778AlaLys: 3.778 ± 0.039
6.453AlaLeu: 6.453 ± 0.058
1.519AlaMet: 1.519 ± 0.023
2.264AlaAsn: 2.264 ± 0.029
2.864AlaPro: 2.864 ± 0.039
2.74AlaGln: 2.74 ± 0.033
2.939AlaArg: 2.939 ± 0.032
5.152AlaSer: 5.152 ± 0.051
3.345AlaThr: 3.345 ± 0.04
4.908AlaVal: 4.908 ± 0.048
0.708AlaTrp: 0.708 ± 0.014
1.658AlaTyr: 1.658 ± 0.026
0.0AlaXaa: 0.0 ± 0.0
Cys
1.169CysAla: 1.169 ± 0.022
0.662CysCys: 0.662 ± 0.014
1.036CysAsp: 1.036 ± 0.022
1.333CysGlu: 1.333 ± 0.029
0.944CysPhe: 0.944 ± 0.019
1.418CysGly: 1.418 ± 0.026
0.634CysHis: 0.634 ± 0.017
1.144CysIle: 1.144 ± 0.024
1.329CysLys: 1.329 ± 0.026
2.183CysLeu: 2.183 ± 0.032
0.449CysMet: 0.449 ± 0.012
0.911CysAsn: 0.911 ± 0.018
1.233CysPro: 1.233 ± 0.031
1.092CysGln: 1.092 ± 0.025
1.232CysArg: 1.232 ± 0.021
2.012CysSer: 2.012 ± 0.032
1.195CysThr: 1.195 ± 0.025
1.363CysVal: 1.363 ± 0.027
0.306CysTrp: 0.306 ± 0.01
0.688CysTyr: 0.688 ± 0.015
0.0CysXaa: 0.0 ± 0.0
Asp
2.897AspAla: 2.897 ± 0.027
1.096AspCys: 1.096 ± 0.024
2.931AspAsp: 2.931 ± 0.038
3.702AspGlu: 3.702 ± 0.043
2.275AspPhe: 2.275 ± 0.028
3.294AspGly: 3.294 ± 0.041
1.176AspHis: 1.176 ± 0.02
2.995AspIle: 2.995 ± 0.031
2.866AspLys: 2.866 ± 0.033
5.096AspLeu: 5.096 ± 0.045
1.156AspMet: 1.156 ± 0.019
1.984AspAsn: 1.984 ± 0.031
2.629AspPro: 2.629 ± 0.032
1.883AspGln: 1.883 ± 0.026
2.398AspArg: 2.398 ± 0.033
4.126AspSer: 4.126 ± 0.047
2.507AspThr: 2.507 ± 0.029
3.273AspVal: 3.273 ± 0.039
0.676AspTrp: 0.676 ± 0.015
1.688AspTyr: 1.688 ± 0.022
0.001AspXaa: 0.001 ± 0.0
Glu
4.705GluAla: 4.705 ± 0.051
1.346GluCys: 1.346 ± 0.039
4.523GluAsp: 4.523 ± 0.046
7.92GluGlu: 7.92 ± 0.102
2.25GluPhe: 2.25 ± 0.027
3.851GluGly: 3.851 ± 0.038
1.577GluHis: 1.577 ± 0.023
3.616GluIle: 3.616 ± 0.039
5.848GluLys: 5.848 ± 0.075
6.396GluLeu: 6.396 ± 0.064
1.79GluMet: 1.79 ± 0.024
3.521GluAsn: 3.521 ± 0.04
2.54GluPro: 2.54 ± 0.034
3.199GluGln: 3.199 ± 0.045
4.025GluArg: 4.025 ± 0.061
4.511GluSer: 4.511 ± 0.045
3.535GluThr: 3.535 ± 0.032
4.371GluVal: 4.371 ± 0.042
0.758GluTrp: 0.758 ± 0.018
1.875GluTyr: 1.875 ± 0.025
0.001GluXaa: 0.001 ± 0.0
Phe
2.201PheAla: 2.201 ± 0.031
1.002PheCys: 1.002 ± 0.02
1.848PheAsp: 1.848 ± 0.027
2.175PheGlu: 2.175 ± 0.028
1.85PhePhe: 1.85 ± 0.031
2.339PheGly: 2.339 ± 0.036
1.092PheHis: 1.092 ± 0.02
2.151PheIle: 2.151 ± 0.032
2.083PheLys: 2.083 ± 0.028
4.227PheLeu: 4.227 ± 0.05
0.826PheMet: 0.826 ± 0.017
1.564PheAsn: 1.564 ± 0.025
1.943PhePro: 1.943 ± 0.03
1.836PheGln: 1.836 ± 0.021
1.923PheArg: 1.923 ± 0.022
3.555PheSer: 3.555 ± 0.039
2.253PheThr: 2.253 ± 0.028
2.416PheVal: 2.416 ± 0.033
0.528PheTrp: 0.528 ± 0.015
1.377PheTyr: 1.377 ± 0.023
0.0PheXaa: 0.0 ± 0.0
Gly
3.428GlyAla: 3.428 ± 0.042
1.228GlyCys: 1.228 ± 0.022
2.97GlyAsp: 2.97 ± 0.039
3.742GlyGlu: 3.742 ± 0.046
2.491GlyPhe: 2.491 ± 0.035
3.805GlyGly: 3.805 ± 0.059
1.476GlyHis: 1.476 ± 0.025
3.094GlyIle: 3.094 ± 0.033
4.116GlyLys: 4.116 ± 0.048
5.084GlyLeu: 5.084 ± 0.051
1.353GlyMet: 1.353 ± 0.025
2.643GlyAsn: 2.643 ± 0.032
2.617GlyPro: 2.617 ± 0.075
2.473GlyGln: 2.473 ± 0.03
3.117GlyArg: 3.117 ± 0.043
5.048GlySer: 5.048 ± 0.05
3.462GlyThr: 3.462 ± 0.04
3.456GlyVal: 3.456 ± 0.035
0.773GlyTrp: 0.773 ± 0.02
1.907GlyTyr: 1.907 ± 0.027
0.002GlyXaa: 0.002 ± 0.001
His
1.309HisAla: 1.309 ± 0.02
0.706HisCys: 0.706 ± 0.018
0.953HisAsp: 0.953 ± 0.02
1.404HisGlu: 1.404 ± 0.021
1.112HisPhe: 1.112 ± 0.019
1.452HisGly: 1.452 ± 0.021
0.859HisHis: 0.859 ± 0.02
1.36HisIle: 1.36 ± 0.023
1.408HisLys: 1.408 ± 0.022
2.801HisLeu: 2.801 ± 0.034
0.581HisMet: 0.581 ± 0.013
0.97HisAsn: 0.97 ± 0.017
1.483HisPro: 1.483 ± 0.024
1.161HisGln: 1.161 ± 0.021
1.427HisArg: 1.427 ± 0.022
2.146HisSer: 2.146 ± 0.031
1.263HisThr: 1.263 ± 0.021
1.553HisVal: 1.553 ± 0.025
0.361HisTrp: 0.361 ± 0.012
0.867HisTyr: 0.867 ± 0.017
0.0HisXaa: 0.0 ± 0.0
Ile
3.07IleAla: 3.07 ± 0.031
1.234IleCys: 1.234 ± 0.024
2.392IleAsp: 2.392 ± 0.028
2.962IleGlu: 2.962 ± 0.037
2.22IlePhe: 2.22 ± 0.038
2.5IleGly: 2.5 ± 0.03
1.391IleHis: 1.391 ± 0.02
2.795IleIle: 2.795 ± 0.035
3.089IleLys: 3.089 ± 0.038
5.042IleLeu: 5.042 ± 0.038
1.085IleMet: 1.085 ± 0.022
2.212IleAsn: 2.212 ± 0.03
2.881IlePro: 2.881 ± 0.034
2.463IleGln: 2.463 ± 0.031
2.513IleArg: 2.513 ± 0.033
4.171IleSer: 4.171 ± 0.04
2.923IleThr: 2.923 ± 0.035
3.008IleVal: 3.008 ± 0.033
0.601IleTrp: 0.601 ± 0.016
1.679IleTyr: 1.679 ± 0.024
0.001IleXaa: 0.001 ± 0.001
Lys
4.176LysAla: 4.176 ± 0.041
1.245LysCys: 1.245 ± 0.023
3.532LysAsp: 3.532 ± 0.04
5.927LysGlu: 5.927 ± 0.074
1.951LysPhe: 1.951 ± 0.029
3.596LysGly: 3.596 ± 0.058
1.608LysHis: 1.608 ± 0.024
3.286LysIle: 3.286 ± 0.035
5.532LysLys: 5.532 ± 0.071
5.801LysLeu: 5.801 ± 0.045
1.591LysMet: 1.591 ± 0.022
2.831LysAsn: 2.831 ± 0.032
3.081LysPro: 3.081 ± 0.044
3.031LysGln: 3.031 ± 0.04
3.605LysArg: 3.605 ± 0.039
4.354LysSer: 4.354 ± 0.048
3.477LysThr: 3.477 ± 0.037
3.848LysVal: 3.848 ± 0.04
0.696LysTrp: 0.696 ± 0.014
1.936LysTyr: 1.936 ± 0.031
0.0LysXaa: 0.0 ± 0.0
Leu
6.2LeuAla: 6.2 ± 0.05
2.186LeuCys: 2.186 ± 0.03
4.829LeuAsp: 4.829 ± 0.043
7.019LeuGlu: 7.019 ± 0.071
3.602LeuPhe: 3.602 ± 0.045
5.165LeuGly: 5.165 ± 0.048
2.674LeuHis: 2.674 ± 0.036
4.346LeuIle: 4.346 ± 0.043
6.586LeuLys: 6.586 ± 0.057
10.061LeuLeu: 10.061 ± 0.1
2.046LeuMet: 2.046 ± 0.027
3.869LeuAsn: 3.869 ± 0.04
5.33LeuPro: 5.33 ± 0.05
5.631LeuGln: 5.631 ± 0.061
5.132LeuArg: 5.132 ± 0.051
7.819LeuSer: 7.819 ± 0.062
5.028LeuThr: 5.028 ± 0.044
5.471LeuVal: 5.471 ± 0.051
1.11LeuTrp: 1.11 ± 0.02
2.855LeuTyr: 2.855 ± 0.032
0.001LeuXaa: 0.001 ± 0.001
Met
1.61MetAla: 1.61 ± 0.022
0.45MetCys: 0.45 ± 0.013
1.284MetAsp: 1.284 ± 0.021
1.868MetGlu: 1.868 ± 0.024
0.838MetPhe: 0.838 ± 0.017
1.234MetGly: 1.234 ± 0.023
0.498MetHis: 0.498 ± 0.013
0.991MetIle: 0.991 ± 0.019
1.647MetLys: 1.647 ± 0.023
2.082MetLeu: 2.082 ± 0.03
0.627MetMet: 0.627 ± 0.016
1.036MetAsn: 1.036 ± 0.02
1.011MetPro: 1.011 ± 0.021
1.038MetGln: 1.038 ± 0.02
1.038MetArg: 1.038 ± 0.018
1.567MetSer: 1.567 ± 0.021
1.175MetThr: 1.175 ± 0.021
1.424MetVal: 1.424 ± 0.022
0.263MetTrp: 0.263 ± 0.01
0.678MetTyr: 0.678 ± 0.015
0.0MetXaa: 0.0 ± 0.0
Asn
2.379AsnAla: 2.379 ± 0.031
0.981AsnCys: 0.981 ± 0.022
1.753AsnAsp: 1.753 ± 0.027
2.589AsnGlu: 2.589 ± 0.035
1.646AsnPhe: 1.646 ± 0.024
2.763AsnGly: 2.763 ± 0.038
1.018AsnHis: 1.018 ± 0.019
2.565AsnIle: 2.565 ± 0.029
2.632AsnLys: 2.632 ± 0.031
4.143AsnLeu: 4.143 ± 0.047
0.994AsnMet: 0.994 ± 0.017
1.891AsnAsn: 1.891 ± 0.031
2.327AsnPro: 2.327 ± 0.035
1.765AsnGln: 1.765 ± 0.028
2.028AsnArg: 2.028 ± 0.024
3.501AsnSer: 3.501 ± 0.035
2.283AsnThr: 2.283 ± 0.027
2.505AsnVal: 2.505 ± 0.033
0.509AsnTrp: 0.509 ± 0.013
1.304AsnTyr: 1.304 ± 0.021
0.0AsnXaa: 0.0 ± 0.0
Pro
3.644ProAla: 3.644 ± 0.043
1.034ProCys: 1.034 ± 0.025
2.619ProAsp: 2.619 ± 0.028
3.843ProGlu: 3.843 ± 0.036
1.922ProPhe: 1.922 ± 0.031
3.626ProGly: 3.626 ± 0.107
1.253ProHis: 1.253 ± 0.019
1.959ProIle: 1.959 ± 0.031
2.742ProLys: 2.742 ± 0.034
4.611ProLeu: 4.611 ± 0.044
0.917ProMet: 0.917 ± 0.017
1.891ProAsn: 1.891 ± 0.027
4.152ProPro: 4.152 ± 0.081
2.298ProGln: 2.298 ± 0.027
2.466ProArg: 2.466 ± 0.031
4.873ProSer: 4.873 ± 0.056
2.598ProThr: 2.598 ± 0.031
3.698ProVal: 3.698 ± 0.041
0.54ProTrp: 0.54 ± 0.014
1.463ProTyr: 1.463 ± 0.022
0.001ProXaa: 0.001 ± 0.0
Gln
2.992GlnAla: 2.992 ± 0.034
0.965GlnCys: 0.965 ± 0.023
2.241GlnAsp: 2.241 ± 0.027
3.709GlnGlu: 3.709 ± 0.049
1.484GlnPhe: 1.484 ± 0.023
2.436GlnGly: 2.436 ± 0.032
1.292GlnHis: 1.292 ± 0.022
2.26GlnIle: 2.26 ± 0.03
3.215GlnLys: 3.215 ± 0.04
4.609GlnLeu: 4.609 ± 0.049
1.135GlnMet: 1.135 ± 0.021
2.075GlnAsn: 2.075 ± 0.03
2.281GlnPro: 2.281 ± 0.033
3.058GlnGln: 3.058 ± 0.061
2.65GlnArg: 2.65 ± 0.032
3.159GlnSer: 3.159 ± 0.038
2.378GlnThr: 2.378 ± 0.029
2.797GlnVal: 2.797 ± 0.031
0.523GlnTrp: 0.523 ± 0.013
1.284GlnTyr: 1.284 ± 0.023
0.0GlnXaa: 0.0 ± 0.0
Arg
3.026ArgAla: 3.026 ± 0.03
1.109ArgCys: 1.109 ± 0.023
2.659ArgAsp: 2.659 ± 0.035
3.78ArgGlu: 3.78 ± 0.052
1.911ArgPhe: 1.911 ± 0.025
2.815ArgGly: 2.815 ± 0.042
1.396ArgHis: 1.396 ± 0.024
2.631ArgIle: 2.631 ± 0.032
4.043ArgLys: 4.043 ± 0.053
4.776ArgLeu: 4.776 ± 0.044
1.148ArgMet: 1.148 ± 0.017
2.259ArgAsn: 2.259 ± 0.027
2.372ArgPro: 2.372 ± 0.035
2.491ArgGln: 2.491 ± 0.036
3.598ArgArg: 3.598 ± 0.047
3.989ArgSer: 3.989 ± 0.056
2.693ArgThr: 2.693 ± 0.033
2.97ArgVal: 2.97 ± 0.032
0.626ArgTrp: 0.626 ± 0.016
1.619ArgTyr: 1.619 ± 0.021
0.001ArgXaa: 0.001 ± 0.0
Ser
5.242SerAla: 5.242 ± 0.054
1.874SerCys: 1.874 ± 0.031
4.027SerAsp: 4.027 ± 0.045
5.184SerGlu: 5.184 ± 0.049
3.146SerPhe: 3.146 ± 0.031
4.969SerGly: 4.969 ± 0.047
2.03SerHis: 2.03 ± 0.029
3.62SerIle: 3.62 ± 0.036
4.581SerLys: 4.581 ± 0.038
7.898SerLeu: 7.898 ± 0.059
1.6SerMet: 1.6 ± 0.023
3.066SerAsn: 3.066 ± 0.035
5.05SerPro: 5.05 ± 0.056
3.606SerGln: 3.606 ± 0.041
4.095SerArg: 4.095 ± 0.06
9.119SerSer: 9.119 ± 0.117
4.513SerThr: 4.513 ± 0.045
5.227SerVal: 5.227 ± 0.049
0.966SerTrp: 0.966 ± 0.018
2.274SerTyr: 2.274 ± 0.027
0.002SerXaa: 0.002 ± 0.001
Thr
3.858ThrAla: 3.858 ± 0.04
1.333ThrCys: 1.333 ± 0.032
2.738ThrAsp: 2.738 ± 0.031
3.763ThrGlu: 3.763 ± 0.041
2.222ThrPhe: 2.222 ± 0.029
3.419ThrGly: 3.419 ± 0.044
1.148ThrHis: 1.148 ± 0.021
2.617ThrIle: 2.617 ± 0.029
2.989ThrLys: 2.989 ± 0.029
5.164ThrLeu: 5.164 ± 0.042
1.127ThrMet: 1.127 ± 0.022
1.982ThrAsn: 1.982 ± 0.028
3.092ThrPro: 3.092 ± 0.041
2.097ThrGln: 2.097 ± 0.024
2.356ThrArg: 2.356 ± 0.031
4.648ThrSer: 4.648 ± 0.041
3.033ThrThr: 3.033 ± 0.042
4.107ThrVal: 4.107 ± 0.037
0.666ThrTrp: 0.666 ± 0.015
1.586ThrTyr: 1.586 ± 0.025
0.001ThrXaa: 0.001 ± 0.0
Val
4.083ValAla: 4.083 ± 0.042
1.54ValCys: 1.54 ± 0.024
3.094ValAsp: 3.094 ± 0.033
3.968ValGlu: 3.968 ± 0.036
2.75ValPhe: 2.75 ± 0.032
3.298ValGly: 3.298 ± 0.035
1.585ValHis: 1.585 ± 0.025
3.37ValIle: 3.37 ± 0.035
3.921ValLys: 3.921 ± 0.042
6.344ValLeu: 6.344 ± 0.058
1.399ValMet: 1.399 ± 0.022
2.621ValAsn: 2.621 ± 0.034
3.439ValPro: 3.439 ± 0.036
2.786ValGln: 2.786 ± 0.028
2.957ValArg: 2.957 ± 0.032
5.051ValSer: 5.051 ± 0.05
3.964ValThr: 3.964 ± 0.04
4.309ValVal: 4.309 ± 0.043
0.75ValTrp: 0.75 ± 0.017
1.941ValTyr: 1.941 ± 0.028
0.001ValXaa: 0.001 ± 0.0
Trp
0.651TrpAla: 0.651 ± 0.017
0.249TrpCys: 0.249 ± 0.01
0.689TrpAsp: 0.689 ± 0.019
0.776TrpGlu: 0.776 ± 0.015
0.467TrpPhe: 0.467 ± 0.012
0.649TrpGly: 0.649 ± 0.02
0.314TrpHis: 0.314 ± 0.01
0.648TrpIle: 0.648 ± 0.016
0.927TrpLys: 0.927 ± 0.019
1.193TrpLeu: 1.193 ± 0.021
0.323TrpMet: 0.323 ± 0.01
0.633TrpAsn: 0.633 ± 0.015
0.44TrpPro: 0.44 ± 0.011
0.557TrpGln: 0.557 ± 0.015
0.664TrpArg: 0.664 ± 0.016
0.866TrpSer: 0.866 ± 0.019
0.665TrpThr: 0.665 ± 0.018
0.664TrpVal: 0.664 ± 0.016
0.196TrpTrp: 0.196 ± 0.008
0.385TrpTyr: 0.385 ± 0.011
0.001TrpXaa: 0.001 ± 0.0
Tyr
1.607TyrAla: 1.607 ± 0.021
0.789TyrCys: 0.789 ± 0.018
1.5TyrAsp: 1.5 ± 0.022
1.861TyrGlu: 1.861 ± 0.027
1.433TyrPhe: 1.433 ± 0.024
1.823TyrGly: 1.823 ± 0.027
0.813TyrHis: 0.813 ± 0.016
1.686TyrIle: 1.686 ± 0.022
1.775TyrLys: 1.775 ± 0.031
2.995TyrLeu: 2.995 ± 0.034
0.694TyrMet: 0.694 ± 0.016
1.353TyrAsn: 1.353 ± 0.02
1.379TyrPro: 1.379 ± 0.023
1.336TyrGln: 1.336 ± 0.021
1.746TyrArg: 1.746 ± 0.029
2.419TyrSer: 2.419 ± 0.028
1.654TyrThr: 1.654 ± 0.026
1.802TyrVal: 1.802 ± 0.024
0.4TyrTrp: 0.4 ± 0.013
1.148TyrTyr: 1.148 ± 0.019
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.002XaaAla: 0.002 ± 0.001
0.0XaaCys: 0.0 ± 0.0
0.001XaaAsp: 0.001 ± 0.001
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.001XaaGly: 0.001 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.001XaaLys: 0.001 ± 0.001
0.001XaaLeu: 0.001 ± 0.001
0.0XaaMet: 0.0 ± 0.0
0.001XaaAsn: 0.001 ± 0.001
0.002XaaPro: 0.002 ± 0.001
0.001XaaGln: 0.001 ± 0.001
0.001XaaArg: 0.001 ± 0.001
0.001XaaSer: 0.001 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.058XaaXaa: 0.058 ± 0.01
Statistics based on 7903 proteins (3310111 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski